Hemarthrosis
Joint Diseases
The locked patella. An unusual complication of haemophilia. (1/86)
Mechanical derangements of the knee are an uncommon complication of chronic haemophiliac arthropathy. Two patients with locking of the patella were treated by manipulation. The mechanism of the injury was forced flexion of the knee joint beyond the limit of its restricted range. The injury is a serious one and may take six months to recover. (+info)An acutely painful elbow as a first presentation of von Willebrand's disease. (2/86)
A 26 year old woman presented to the accident and emergency department with a painful right elbow. There had been no history of trauma. Clinical examination suggested an effusion, which was confirmed on radiological examination. Her elbow was aspirated and revealed a haemarthrosis. Subsequent investigations revealed a diagnosis of von Willebrand's disease (vWD). A spontaneously occurring effusion of the elbow may be due to a haemarthrosis. Aspiration of blood in the absence of trauma may lead to a diagnosis of an occult coagulopathy in addition to relieving pain. The diagnosis and treatment of vWD is discussed. (+info)Blood-induced joint damage: a human in vitro study. (3/86)
OBJECTIVE: To investigate mechanisms underlying cartilage damage caused by brief exposure of cartilage to blood, such as that occurring during intraarticular bleeding. METHODS: Human articular cartilage was cultured for 4 days in the presence of blood (components; 7.5-50% volume/volume). The synthesis of cartilage matrix, as determined by proteoglycan synthesis (incorporation of 35SO4(2-)), was measured directly after exposure and after a recovery period of 20 days, during which the cartilage was cultured in the absence of blood or blood components. The production of the cytokines interleukin-1 (IL-1) and tumor necrosis factor a (TNFalpha), which have a destructive effect on cartilage, was determined by enzyme-linked immunosorbent assay, and the viability of chondrocytes was determined by measuring lactate dehydrogenase release and with electron microscopy. The involvement of oxygen metabolites was evaluated by using N-acetylcysteine. RESULTS: Brief exposure to blood resulted in dose-dependent inhibition of proteoglycan synthesis. The combination of mononuclear cells and red blood cells was responsible for this effect. The effect was irreversible, independent of IL-1 and TNFalpha production, and was accompanied by chondrocyte death. These effects were partially prevented by N-acetylcysteine. CONCLUSION: Brief exposure of cartilage to blood, as occurs after a single episode or a limited number of bleeding episodes, results in lasting cartilage damage in vitro, in which cytotoxic oxygen metabolites play a role. (+info)Blood-induced joint damage: a canine in vivo study. (4/86)
OBJECTIVE: To investigate the direct and indirect (via synovial inflammation) effects of intraarticular bleeding on cartilage in vivo. METHODS: Right knees of 14 beagle dogs were injected with autologous blood on days 0 and 2. Cartilage matrix proteoglycan turnover, collagen damage, and synovial inflammation of these knees, including the cartilage-destructive properties of the synovial tissue, were determined and compared with those of the left control knees on day 4 (short-term effects; n = 7) and day 16 (long-term effects; n = 7). RESULTS: Injected knees had a diminished content of proteoglycans in the cartilage matrix, and release of proteoglycans was enhanced (days 4 and 16). The synthesis of proteoglycans was significantly inhibited on day 4 but was enhanced on day 16. On day 4 more collagen was denatured in the injected joint than in the control joint; this effect was no longer detectable on day 16. Synovial tissue showed signs of inflammation on day 4 and day 16 but had cartilage-destructive properties only on day 16. CONCLUSION: In vivo exposure of articular cartilage to blood for a relatively short time results in lasting changes in chondrocyte activity and in cartilage matrix integrity, changes that may predict lasting joint damage over time. Interestingly, the direct effect of blood on cartilage precedes the indirect effect via synovial inflammation. (+info)Characteristics of patients with antiphospholipid syndrome with major bleeding after oral anticoagulant treatment. (5/86)
OBJECTIVE: To study the demographic and clinical characteristics of patients with antiphospholipid syndrome (APS) with serious haemorrhagic complications of anticoagulant treatment in an attempt to establish risk factors for bleeding. METHODS: Patients with APS who were attending our lupus unit and who presented with severe bleeding while receiving oral anticoagulation were studied retrospectively. Severe bleeding was defined by the need for admission to hospital. Demographic data, clinical features, concomitant diseases and drugs, warfarin doses, duration of anticoagulation, and International Normalised Ratios (INR) at the time of bleeding were collected. RESULTS: Fifteen patients were included in the study (12 with systemic lupus erythematosus (SLE) plus APS and 3 with primary APS). The median age was 41.7 (range 27-66) and the median duration of the disease was 12.9 years (range 3-22). Duration of anticoagulation was between 10 days and 17 years. The INR at the time of bleeding was under 3 in 4 patients, between 3 and 4 in 5 patients and above 4 in 6 patients. There were 4 episodes of subdural haematoma, 4 episodes of renal haematoma (two after renal biopsy), 2 episodes of ovarian haemorrhage, 2 episodes of rectal haemorrhage, 1 episode of menorrhagia, 1 episode of haemarthrosis, and 1 episode of spinal haematoma. Concomitant drugs were aspirin in 9 patients, antibiotics in 2 patients, and azathioprine in 3 patients. In 6 patients hypertension was present as a concomitant disease. There were no deaths due to bleeding. Anticoagulant treatment was restarted in all patients and 3 of them had a new episode of bleeding. CONCLUSION: No relation was established between age, duration of oral anticoagulant treatment, and bleeding. Concomitant drugs, mainly aspirin, and high blood pressure were present at the time of bleeding in a large number of patients. (+info)Arthrocentesis of the knee in acute hemophilic arthropathy. (6/86)
In 27 children and young adults with hemophilia presenting acutely painful distended intra-articular hemorrhages of the knee, aspiration was carried out and the patients were followed for a minimum of 24 months. Seventeen patients with classical hemophilia were found to have less than 1 percent of normal plasmal level of antihemophilic factor (AHF). Of the remainder, five were Factor IX, plasma thromboplastin component (PTG), deficient, whereas two patients had Von Willebrand's disease. Aspiration was routinely done in an outpatient clinic, followed by immediate discharge with return to regular activity levels within 48 hours. There were no infections nor rehemorrhages attributable to aspiration technique. (+info)Hemarthrosis: an unusual complication of type 1 neurofibromatosis. (7/86)
Type 1 neurofibromatosis is one of the most common autosomal-dominant disorders and often includes orthopedic manifestations. We report the case of a 48-year-old woman with hemarthrosis caused by a popliteal cyst infiltrated by a diffuse neurofibroma associated with angiodysplasia. Surgical resection of this tumor was followed by postoperative hemorrhagic complications. (+info)Late presentation of congenital factor V deficiency--a case report. (8/86)
Congenital factor deficiency is a rare coagulation disorder, which is inherited in an autosomal recessive manner. The severity of bleeding symptoms in general is only partially related to the degree of factor V deficiency in plasma. In this report, a boy presenting with hemarthrosis in his late adolescence due to congenital factor V deficiency is reported. (+info)Hemarthrosis is a medical term that refers to the presence of blood in a joint space. This condition usually occurs as a result of trauma or injury that causes bleeding into the joint, such as a fracture or dislocation. Certain medical conditions like hemophilia and other bleeding disorders can also make a person more prone to hemarthrosis.
The accumulation of blood in the joint space can cause pain, swelling, warmth, and stiffness, making it difficult for the individual to move the affected joint. In some cases, hemarthrosis may require medical intervention, such as draining the excess blood from the joint or administering clotting factors to help stop the bleeding. If left untreated, hemarthrosis can lead to complications like joint damage and chronic pain.
Joint diseases is a broad term that refers to various conditions affecting the joints, including but not limited to:
1. Osteoarthritis (OA): A degenerative joint disease characterized by the breakdown of cartilage and underlying bone, leading to pain, stiffness, and potential loss of function.
2. Rheumatoid Arthritis (RA): An autoimmune disorder causing inflammation in the synovial membrane lining the joints, resulting in swelling, pain, and joint damage if left untreated.
3. Infectious Arthritis: Joint inflammation caused by bacterial, viral, or fungal infections that spread through the bloodstream or directly enter the joint space.
4. Gout: A type of arthritis resulting from the buildup of uric acid crystals in the joints, typically affecting the big toe and characterized by sudden attacks of severe pain, redness, and swelling.
5. Psoriatic Arthritis (PsA): An inflammatory joint disease associated with psoriasis, causing symptoms such as pain, stiffness, and swelling in the joints and surrounding tissues.
6. Juvenile Idiopathic Arthritis (JIA): A group of chronic arthritis conditions affecting children, characterized by joint inflammation, pain, and stiffness.
7. Ankylosing Spondylitis: A form of arthritis primarily affecting the spine, causing inflammation, pain, and potential fusion of spinal vertebrae.
8. Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion joints, leading to pain and swelling.
9. Tendinitis: Inflammation or degeneration of tendons, which connect muscles to bones, often resulting in pain and stiffness near joints.
These conditions can impact the function and mobility of affected joints, causing discomfort and limiting daily activities. Proper diagnosis and treatment are essential for managing joint diseases and preserving joint health.
Hemarthrosis
Hypoprothrombinemia
Joint effusion
Dysfibrinogenemia
List of ICD-9 codes 710-739: diseases of the musculoskeletal system and connective tissue
Alexei Nikolaevich, Tsarevich of Russia
Factor XIII deficiency
Acquired haemophilia
Post-traumatic arthritis
Tibial plateau fracture
Arthrocentesis
Patella
Cycas revoluta
Posterolateral corner injuries
Jeanne Lusher
Factor X
Blood
Haemophilia
Osteochondritis dissecans
Septic arthritis
Arthritis
List of MeSH codes (C23)
Internal bleeding
Knee pain
Index of trauma and orthopaedics articles
Arthropathy
Hemarthrosis - Wikipedia
Hemarthrosis Definition, Treatment with Causes & Symptoms
The diagnostic validity of magnetic resonance imaging in acute knee injuries with hemarthrosis. A single-blinded evaluation in...
Knee Hemarthrosis and Osteoarthritis
Blood in the joint: effects of hemarthrosis on meniscus health and repair techniques.
Techniques of Embolization for OA and Hemarthrosis - GEST
Knee hemarthrosis after arthroscopic surgery in an athlete with low factor XIII activity | BMC Sports Science, Medicine and...
Feiba Vh Medication: Hemophilia Treatment Side Effects & Dosage
Pediatric Factor VII Deficiency: Practice Essentials, Pathophysiology, Epidemiology
Innohep (Tinzaparin): Uses, Dosage, Side Effects, Interactions, Warning
Geniculate artery embolization for the treatment of refractory hemarthrosis following meniscal repair - American Journal of...
Hemophilia B (Factor IX Deficiency) Treatment & Management: Approach Considerations, Prehospital Care, Emergency Department Care
Factor X deficiency: MedlinePlus Genetics
Distal Femoral Physeal Fractures : Wheeless' Textbook of Orthopaedics
Platelet Disorders: Overview of Platelet Disorders, Pathophysiology of Platelet Disorders, Autoimmune Thrombocytopenias
Calquence: Package Insert - Drugs.com
Thieme E-Journals - The Journal of Knee Surgery / Abstract
Fibrinolytic Disorders | Choose the Right Test
Pathology
Pediatric Factor VII Deficiency: Practice Essentials, Pathophysiology, Epidemiology
RX List database - use generic or medication brand name - GlobalRPH
Why Do My Joints Hurt?
May Chien's Profile | Stanford Profiles
Radial head fracture-dislocation | Radiology Case | Radiopaedia.org
FEIBA Dosage & Rx Info | Uses, Side Effects
Pachydermoperiostosis syndrome
Cytology - Clinical Pathology and Procedures - Merck Veterinary Manual
Haemophilic arthropathy | Radiology Reference Article | Radiopaedia.org
Effusion2
- There is joint effusion (hemarthrosis). (radiopaedia.org)
- The patient is typically unable to return to the ongoing sporting activity, and presents with joint instability, and rapid development of an effusion (hemarthrosis). (bmj.com)
Hemophilia4
- In hemophilia it may occur spontaneously, and recurrent hemarthroses are a major cause of disability in that patient group due to hemophilic arthropathy, requiring synovectomy, joint replacement and increased medical therapy to prevent further bleeding episodes. (wikipedia.org)
- Haemophilic arthropathy refers to permanent joint disease occurring in hemophilia sufferers as a long-term consequence of repeated hemarthrosis . (radiopaedia.org)
- Prophylactic clotting factor regimen not only prevents hemarthrosis that is associated with hemophilia A but also avoids chronic microhemorrhage into joints. (technavio.com)
- For people without hemophilia, hemarthrosis often occurs after an injury. (hemaware.org)
Traumatic1
- Sixty-nine patients with traumatic knee hemarthrosis were evaluated an average of 3 days after trauma by high field (1.5T) magnetic resonance imaging (MRI) using sagittal T1, T2-weighted and coronal 3D-gradient echo images. (nih.gov)
Recurrent hemarthrosis1
- Chronic arthropathy is a late complication of recurrent hemarthrosis in a target joint. (medscape.com)
Intra-articular1
- Fractures are usually intra-articular, causing hemarthrosis. (msdmanuals.com)
Hematomas1
- As physical activity increases in children, hemarthrosis and hematomas occur. (medscape.com)
Symptoms1
- We'll cover hemarthrosis definitions, hemarthrosis causes, and hemarthrosis symptoms, as well as treatment options. (doctorshealthpress.com)
Arthropathy1
- Genetic biomarkers related to hemarthrosis, inflammation, and cartilage structure in pediatric patients with hemophilic arthropathy. (cdc.gov)
Acute1
- The diagnostic validity of magnetic resonance imaging in acute knee injuries with hemarthrosis. (nih.gov)
Hematoma1
- The AirCast Cryo/Cuff gravity cooler system combines the therapeutic benefits of controlled compression with cold therapy to minimize hemarthrosis, edema hematoma, swelling, and pain. (healthproductsforyou.com)
Arthroscopy2
- We should keep in mind of low factor XIII activity case in case of unexplained postoperative hemarthrosis after arthroscopy because consumption of the factor might promote this condition. (biomedcentral.com)
- Hemarthrosis is one of the most common complications after knee arthroscopy [ 1 ]. (biomedcentral.com)
Cartilage2
- Up to a quarter of all severe ligament or capsular knee injuries leading to a hemarthrosis are associated with cartilage damage that can lead to progressive degenerative arthritis. (wikipedia.org)
- Although numerous studies have revealed the harmful effects of blood on cartilage and synovium, there is currently a gap in knowledge regarding the effects of hemarthrosis on meniscus tissue homeostasis, healing, and the development of PTOA following meniscus injury. (duke.edu)
Osteoarthritis4
- How are hemarthrosis and osteoarthritis of the knee diagnosed and treated? (beachwellnessmd.com)
- A physician may also use imaging tests, such as X-rays or MRIs to diagnose knee hemarthrosis or osteoarthritis. (beachwellnessmd.com)
- Both hemarthrosis and osteoarthritis may be treated conservatively with rest, ice, and elevation. (beachwellnessmd.com)
- An innovative and minimally invasive treatment that can be used for both knee hemarthrosis and knee osteoarthritis is geniculate artery embolization . (beachwellnessmd.com)
Inflammation1
- Hemarthrosis is a condition that causes inflammation and pain because of bleeding into the joint. (beachwellnessmd.com)
Diagnosis2
- Hemarthrosis diagnosis begins much the same way as most diagnoses. (doctorshealthpress.com)
- Once a diagnosis has been made, the doctor will then recommend an appropriate treatment for your particular hemarthrosis issues. (doctorshealthpress.com)
Severe3
- The following are usually recommended, depending on how severe the hemarthrosis is. (doctorshealthpress.com)
- Resection of suprapatellar plica and washing out blood clot were performed, and severe postoperative hemarthrosis was progressively occurred. (biomedcentral.com)
- Hemarthrosis is generally not severe except in coagulation factor deficiency. (biomedcentral.com)
Articular1
- Hemarthrosis , or articular bleeding, means bleeding into the joint cavity. (hemaware.org)
Knee joint1
- Allowing for more spontaneity 11, a medicine may cause some unwanted effects 12 degree hemarthrosis of the knee joint. (wbrs.org)
MRIs1
- MRIs low diagnostic validity for intraarticular pathology with hemarthrosis may be attributed to the shifting paramagnetic properties of the blood remains and catabolic processes in meniscal and chondral tissues during the hemoglobin degradation process. (nih.gov)
Mild1
- Arthrocentesis may reveal mild cellular increases and hemarthrosis. (msdvetmanual.com)
Elbow1
- A bleeding into or the presence of blood in a joint: The hemarthrosis in his elbow connection was painful and so Peter was looking forward to having the blood drained. (wordinfo.info)
Diagnose1
- Synovial fluid analysis is another method to diagnose Hemarthrosis. (wikipedia.org)
Occurs1
- Bleeding into joint spaces (hemarthrosis) occasionally occurs. (medlineplus.gov)
Ligament1
- Also, an injury like a torn ligament or knee fracture can cause bleeding into a joint (hemarthrosis). (webmd.com)
Increases1
- Reducing hemarthroses events using intravenous administration of blood clotting factor concentrate on a regular basis starting in early childhood, reduces joint deterioration and increases the person's quality of life compared to "on demand" treatment (treating after a bleed). (wikipedia.org)
Treatment1
- Oddly enough, many of your doctor's recommendations for hemarthrosis treatment may be pretty easy to follow. (doctorshealthpress.com)
Joint pain1
- Hemarthrosis is a condition that can cause joint pain and other issues, and it's a problem that is more common than you might think. (doctorshealthpress.com)
Condition2
- This condition is called hemarthrosis and warrants urgent medical care. (arthritis-health.com)
- In some cases, blood may accumulate around the damaged joint, a condition called hemarthrosis. (cuanschutz.edu)
Blood3
- Simply put, hemarthrosis is when the blood vessels within your joints begin to bleed. (doctorshealthpress.com)
- For hemarthrosis, a physician may recommend draining the blood from the joint. (beachwellnessmd.com)
- Scholars@Duke publication: Blood in the joint: effects of hemarthrosis on meniscus health and repair techniques. (duke.edu)
Pain1
- Home » Pain » What Is Hemarthrosis? (doctorshealthpress.com)
Children1
- children with hemarthrosis. (intramed.net)
Patient2
- Hemarthrosis is diagnosed through the methods listed below: A physical examination is the first step, with the joints of the patient moved and bent to study possible loss of functioning. (wikipedia.org)
- For example, the tutor may hand out the first sheet that describes a patient presenting with hemarthrosis. (bcmj.org)
Lead1
- If left untreated, hemarthrosis can lead to permanent joint damage, as well as damage to the tendons, ligaments, and soft tissues around the joints. (beachwellnessmd.com)
Factor2
- We report a thirteen-year-old tennis player with knee hemarthrosis caused by low factor XIII activity. (biomedcentral.com)
- We here present a case of postoperative hemarthrosis caused by low activity level of this factor. (biomedcentral.com)