Diseases, dysfunctions, or disorders of or located in the iris.
The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.
A plant genus of the family IRIDACEAE that contains IRIP, a type-1 ribosome-inactivating protein, and iridals (TRITERPENES).

Iris cysts in children: classification, incidence, and management. The 1998 Torrence A Makley Jr Lecture. (1/119)

BACKGROUND: Iris cysts in children are uncommon and there is relatively little information on their classification, incidence, and management. METHODS: The records of all children under age 20 years who were diagnosed with iris cyst were reviewed and the types and incidence of iris cysts of childhood determined. Based on these observations recommendations were made regarding management of iris cysts in children. RESULTS: Of 57 iris cysts in children, 53 were primary and four were secondary. There were 44 primary cysts of the iris pigment epithelium, 34 of which were of the peripheral or iridociliary type, accounting for 59% of all childhood iris cysts. It was most commonly diagnosed in the teenage years, more common in girls (68%), was not recognised in infancy, remained stationary or regressed, and required no treatment. The five mid-zonal pigment epithelial cysts were diagnosed at a mean age of 14 years, were more common in boys (83%), remained stationary, and required no treatment. The pupillary type of pigment epithelial cyst was generally recognised in infancy and, despite involvement of the pupillary aperture, also required no treatment. There were nine cases of primary iris stromal cysts, accounting for 16% of all childhood iris cysts. This cyst was usually diagnosed in infancy, was generally progressive, and required treatment in eight of the nine cases, usually by aspiration and cryotherapy or surgical resection. Among the secondary iris cysts, two were post-traumatic epithelial ingrowth cysts and two were tumour induced cysts, one arising from an intraocular lacrimal gland choristoma and one adjacent to a peripheral iris naevus. CONCLUSIONS: Most iris cysts of childhood are primary pigment epithelial cysts and require no treatment. However, the iris stromal cyst, usually recognised in infancy, is generally an aggressive lesion that requires treatment by aspiration or surgical excision.  (+info)

Increase in orthotopic murine corneal transplantation rejection rate with anterior synechiae. (2/119)

PURPOSE: To evaluate the immunologic effect of anterior synechiae (AS) in a murine model of corneal transplantation. METHODS: Orthotopic penetrating keratoplasty with 12 interrupted sutures was performed on C57BL/6 donor mice and BALB/c recipient mice without AS (AS- group). In contrast to suturing in the AS- group, 3 of the 12 sutures were placed to create AS (AS+ group). The average graft opacity scores and rejection rates of both groups were compared. Cytotoxic T-lymphocyte (CTL) reactions and delayed hypersensitivity (DH) were evaluated 3 weeks after transplantation. Corneal cytokine expression was evaluated. RESULTS: The opacity scores of the AS+ group were consistently greater than those of the AS- group, and the rejection rate of the AS+ group was significantly greater than that of the AS- group (86% versus 54%, P = 0.03). The AS+ group had significantly higher CTL activity compared with the AS- group. There was no significant difference in DH between the two groups. The cytokine expression pattern in the AS+ group became similar to that of the AS- group in which the grafts were rejected. CONCLUSIONS: These findings indicate that AS impairs ocular immune privilege by mediating CTL activity, but without intensifying the DH response. Therefore, AS is a critical risk factor in allograft rejection in a murine model of corneal transplantation.  (+info)

Intraocular gnathostomiasis. (3/119)

We report a rare case of intraocular Gnathostomiasis, where a live worm, intracameral in location, was successfully removed. Its identity was confirmed by microscopy.  (+info)

Meta-analysis of randomised controlled trials comparing latanoprost with timolol in the treatment of patients with open angle glaucoma or ocular hypertension. (4/119)

AIM: To evaluate the comparative efficacy and tolerance of latanoprost versus timolol through a meta-analysis of randomised controlled trials (RCTs). METHODS: Systematic retrieval of RCTs of latanoprost versus timolol to allow pooling of results from head to head comparison studies. Quality of trials was assessed based on randomisation, masking, and withdrawal. Sensitivity analyses were used to estimate the effects of quality of study on outcomes. The data sources were Medline, Embase, Scientific Citation Index, Merck Glaucoma, and Pharmacia and Upjohn ophthalmology databases. There were 1256 patients with open angle glaucoma or ocular hypertension reported in 11 trials of latanoprost versus timolol. The main outcome measures were (i) percentage intraocular pressure (IOP) reduction for efficacy; (ii) relative risk, risk difference, and number needed to harm for side effects such as hyperaemia, conjunctivitis, increased pigmentation, hypotension, and bradycardia expressed as dichotomous outcomes; and (iii) reduction in systemic blood pressure and heart rate as side effects. RESULTS: Both 0.005% latanoprost once daily and 0.5% timolol twice daily reduced IOP. The percentage reductions in IOP from baseline (mean (SE)) produced by latanoprost and timolol were 30.2 (2.3) and 26.9 (3.4) at 3 months. The difference in IOP reduction between the two treatments were 5.0 (95% confidence intervals 2.8, 7.3). However, latanoprost caused iris pigmentation in more patients than timolol (relative risk = 8.01, 95% confidence intervals 1.87, 34.30). The 2 year risk with latanoprost reached 18% (51/277). Hyperaemia was also more often observed with latanoprost (relative risk =2.20, 95% confidence intervals 1.33, 3.64). Timolol caused a significant reduction in heart rate of 4 beats/minute (95% confidence interval 2, 6). CONCLUSION: This meta-analysis suggests that latanoprost is more effective than timolol in lowering IOP. However, it often causes iris pigmentation. While current evidence suggests that this pigmentation is benign, careful lifetime evaluation of patients is still justified.  (+info)

Deletion in the OA1 gene in a family with congenital X linked nystagmus. (5/119)

AIMS: To elucidate the molecular genetic defect of X linked congenital nystagmus associated with macular hypoplasia in three white males of a three generation family with clear features of ocular albinism in only one of them. METHODS: A three generation family with congenital nystagmus following X linked inheritance, and associated with macular hypoplasia was clinically examined (three males and two obligate carriers). Flash VEP was performed to look for albino misrouting. DNA samples were subjected to PCR and subsequent analysis using SSCP for all exons of the OA1 gene. RT-PCR was performed on a mRNA preparation from a naevus from one patient. PCR products presenting divergent banding patterns in SSCP and from the RT-PCR were sequenced directly using cycle sequencing with fluorescent chain termination nucleotides and electrophoresis in a capillary sequencer. RESULTS: The index case (patient 1, IV.1) was diagnosed with X linked OA1 at the age of 3 months because of typical clinical features: congenital nystagmus, iris translucency, macular hypoplasia, fundus hypopigmentation, normal pigmentation of skin and hair, and typical carrier signs of OA1 in his mother and maternal grandmother. Pigmentation of the iris and fundus had increased at the last examination at age 4 years. Albino misrouting was present at this age. In the maternal uncle (III.3, 51 years) who also suffered from congenital nystagmus there was clear macular hypoplasia and stromal focal hypopigmentation of the iris but no iris translucency or fundus hypopigmentation. Patient 3 (II.3, 79 years, maternal uncle of patient III.3) had congenital nystagmus and was highly myopic. The fundus appearance was typical for excessive myopia including macular changes. The iris did not show any translucency. Molecular genetic analysis revealed a novel 14 bp deletion of the OA1 gene at nt816 in exon 6. The mutation abolishes four amino acids (Leu 253-Ile-Ile-Cys) and covers the splice site. Nucleotides 814/815 are used as a new splice donor thus producing a frame shift in codon 252 and a new stop codon at codon 259. CONCLUSIONS: Macular hypoplasia without clinically detectable hypopigmentation as the only sign of X linked OA1 has been reported occasionally in African-American, Japanese, and white patients. The present family shows absent hypopigmentation in two patients of a white family with a deletion in the OA1 gene. We propose a model of OA1 that allows increase of pigmentation with age. We hypothesise that macular hypoplasia in all forms of albinism depends on the extracellular DOPA level during embryogenesis, and that in OA1 postnatal normalisation of the extracellular DOPA level due to delayed distribution and membrane budding/fusion of melanosomes in melanocytes results in increasing pigmentation.  (+info)

Fibrous congenital iris membranes with pupillary distortion. (6/119)

BACKGROUND: In 1986 Cibis and associates described 2 children with a new type of congenital pupillary-iris-lens membrane with goniodysgenesis that was unilateral, sporadic, and progressive. These membranes were different from the common congenital pupillary strands that extend from 1 portion of the iris collarette to another or from the iris collarette to a focal opacity on the anterior lens surface. They also differed from the stationary congenital hypertrophic pupillary membranes that partially occlude the pupil, originating from multiple sites on the iris collarette, but not attaching directly to the lens. CASE MATERIAL: The present report is an account of 7 additional infants with congenital iris membranes, similar to those reported by Cibis and associates, which caused pupillary distortion and were variably associated with adhesions to the lens, goniodysgenesis, and progressive occlusion or seclusion of the pupil. Six of the 7 patients required surgery to open their pupils for visual purposes or to abort angle closure glaucoma. A remarkable finding was that the lenses in the area of the newly created pupils were clear, allowing an unobstructed view of normal fundi. CONCLUSION: This type of fibrous congenital iris membrane is important to recognize because of its impact on vision and its tendency to progress toward pupillary occlusion. Timely surgical intervention can abort this progressive course and allow vision to be preserved.  (+info)

Ocular manifestations of congenital rubella syndrome in a developing country. (7/119)

PURPOSE: To describe the ocular manifestations of congenital rubella syndrome (CRS), a common cause of congenital cataracts in developing countries. METHODS: Retrospective analysis of case records of 46 sero-positive infants under 12 months of age who presented at Aravind Eye Hospital, Madurai between July 1993 and February 2001. The ocular and systemic examination details were recorded. RESULTS: Both eyes were affected in 41 (89%) patients. Cataract was present in 81 (93.1%) eyes; most of them were nuclear cataract (79, 97.5%). Other common ocular presentations included microphthalmos in 74 (85.1%) eyes, iris abnormalities in 51 (58.6%) eyes, and pigmentary retinopathy in 33 (37.9%) eyes. Cataract, microphthalmos and iris hypoplasia was a common combination present in 49 (56.3%) eyes. Systemic manifestations included cardiac anomalies in 23 (50%) and neurological anomalies in 16 (34%) children. Multi-system involvement was present in 32 (70%) children. Low birth weight (below 2 kg) was seen in 30% infants. CONCLUSION: CRS may present with a wide spectrum of ocular and systemic findings and requires a high index of suspicion for diagnosis. Any sick infant with unilateral or bilateral congenital cataract should be investigated thoroughly for CRS.  (+info)

Surgical approaches to the management of epithelial cysts. (8/119)

PURPOSE: The purpose of this study was to review management strategies for treatment of epithelial cysts. STUDY DESIGN: Retrospective consecutive interventional case series. METHODS: Charts of patients treated for epithelial ingrowth over a 10-year period by a single surgeon (J.A.H.) were reviewed. Cases of epithelial cysts were identified and the following data were recorded: details of ocular history, preoperative and postoperative visual acuity, intraocular pressure (IOP), ocular examination findings, type of surgical intervention, and details of subsequent procedures performed. RESULTS: Seven eyes with epithelial cysts were identified. Patients ranged in age from 1 1/2 years to 53 years at presentation. Three patients were children. Four cysts were due to trauma, one was presumably congenital, one developed after corneal perforation in an eye with Terrien's marginal degeneration, and one developed after penetrating keratoplasty. Three patients were treated with vitrectomy, en bloc resection of the cyst and associated tissue, fluid-air exchange, and cryotherapy. Four patients were treated with conservative strategy consisting of cyst aspiration (three cases) or local excision (one "keratin pearl" cyst) and endolaser photocoagulation of the collapsed cyst wall or base. In all cases, the epithelial tissue was successfully eradicated; one case required a second excision (follow-up, 9 months to 78 months; mean, 45 months). Two eyes required subsequent surgery for elevated IOP, two for cataract extraction, and one for a second penetrating keratoplasty. Final visual acuity ranged from 20/20 to hand motions, depending on associated ocular damage. Best visual results were obtained in the more conservatively managed eyes. CONCLUSION: Epithelial cysts can be managed conservatively in selected patients with good results. This strategy may be particularly useful in children, in whom preservation of the lens, iris, and other structures may facilitate amblyopia management.  (+info)

Iris diseases refer to a variety of conditions that affect the iris, which is the colored part of the eye that regulates the amount of light reaching the retina by adjusting the size of the pupil. Some common iris diseases include:

1. Iritis: This is an inflammation of the iris and the adjacent tissues in the eye. It can cause pain, redness, photophobia (sensitivity to light), and blurred vision.
2. Aniridia: A congenital condition characterized by the absence or underdevelopment of the iris. This can lead to decreased visual acuity, sensitivity to light, and an increased risk of glaucoma.
3. Iris cysts: These are fluid-filled sacs that form on the iris. They are usually benign but can cause vision problems if they grow too large or interfere with the function of the eye.
4. Iris melanoma: A rare type of eye cancer that develops in the pigmented cells of the iris. It can cause symptoms such as blurred vision, floaters, and changes in the appearance of the iris.
5. Iridocorneal endothelial syndrome (ICE): A group of rare eye conditions that affect the cornea and the iris. They are characterized by the growth of abnormal tissue on the back surface of the cornea and can lead to vision loss.

It is important to seek medical attention if you experience any symptoms of iris diseases, as early diagnosis and treatment can help prevent complications and preserve your vision.

In medical terms, the iris refers to the colored portion of the eye that surrounds the pupil. It is a circular structure composed of thin, contractile muscle fibers (radial and circumferential) arranged in a regular pattern. These muscles are controlled by the autonomic nervous system and can adjust the size of the pupil in response to changes in light intensity or emotional arousal. By constricting or dilating the iris, the amount of light entering the eye can be regulated, which helps maintain optimal visual acuity under various lighting conditions.

The color of the iris is determined by the concentration and distribution of melanin pigments within the iris stroma. The iris also contains blood vessels, nerves, and connective tissue that support its structure and function. Anatomically, the iris is continuous with the ciliary body and the choroid, forming part of the uveal tract in the eye.

I am not aware of a specific medical definition for "Iris Plant." The term "iris" in a medical context usually refers to the colored part of the eye that regulates the size of the pupil and controls the amount of light that enters the eye.

However, the "Iris Plant" (Iris spp.) is a type of perennial flowering plant that belongs to the family Iridaceae. It is native to temperate regions of the Northern Hemisphere, although there are also some species found in tropical and subtropical areas. The iris plant has long, sword-shaped leaves and showy flowers that come in various colors, including blue, purple, yellow, white, and red.

If you have any further questions or need information related to a medical topic, please let me know!

  • Bearded irises grow from rhizomes and true roots grow from the lower surface of the rhizome and penetrate the ground to quite a considerable depth. (cdn-iris.ca)
  • This will minimize chances of disease invading the rhizomes. (cdn-iris.ca)
  • Cultivate the soil between the irises frequently during the summer to prevent weed growth, being careful not to injure the rhizomes. (cdn-iris.ca)
  • Your new permanent iris bed should be deeply prepared and well enriched with organic matter prior to planting, and the iris should be planted very shallowly to avoid rotting the rhizomes. (garden.org)
  • Named after the distinctive fuzzy beards upon their lower petals, or falls, Bearded Iris grow from modified stems called rhizomes, which extend horizontally in the soil and send out roots and shoots from nodes. (whiteflowerfarm.com)
  • Rhizomatous irises have rhizomes as rootstocks, close to or on the surface, or just below ground-level, which produce linear to sword-shaped leaves, nearly always in basal fans, and simple or branched flower stems. (backyardgardener.com)
  • According to the Centers for Disease Control and Prevention (CDC) , two decades ago the rates of gonorrhea and syphilis had dropped significantly, and new diagnostic techniques made diagnosis of chlamydia easier. (wildirismedicaleducation.com)
  • By Dotson GS, Maier A, Parker A, Haber L. Cincinnati, OH: US Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupa- tional Safety and Health, DHHS (NIOSH) Publication 2016-171. (cdc.gov)
  • Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
  • The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • Details for: Global action plan for the prevention and control of noncommunicable diseases 2013-2020. (who.int)
  • 2 Noncommunicable diseases progress monitor 2020 [website]. (who.int)
  • Resolution AFR/RC67/12, Regional framework for integrating essential noncommunicable disease services in primary health care. (who.int)
  • 6 Assessing national capacity for the prevention and control of noncommunicable diseases: report of the 2019 global survey [website]. (who.int)
  • Irises will normally bloom the year after planting. (cdn-iris.ca)
  • Iris grow/expand outward from the leaf end of the rhizome (bulb), so keep this in mind when arranging and planting them. (oldhousegardens.com)
  • Though iris are drought-tolerant and will rot in soil that's too wet, they'll need regular moisture the first few months after planting as they reestablish themselves. (oldhousegardens.com)
  • After a few years of vigorous growth, your iris may get so crowded that their bloom and health begin to suffer. (oldhousegardens.com)
  • African iris will bloom best on rich, moist soil but will tolerate moderately dry soil conditions, growing in full sun to partial shade. (ufl.edu)
  • Siberian irises bloom from midspring to early summer. (backyardgardener.com)
  • The last novel written by author Iris Murdoch before she died reveals signs of the first stages of Alzheimer's disease, according to a study published in the latest online issue of Brain. (ucl.ac.uk)
  • As part of their on-going research into the effects of Alzheimer's disease on language, scientists at University College London and Medical Research Council's Cognition and Brain Sciences Unit decided to compare three of Dame Iris Murdoch's works, including her final novel written just before she was diagnosed with the disease. (ucl.ac.uk)
  • Under the Net, Murdoch's first published work, The Sea, The Sea which was written during the prime of her creative life and her final novel, Jackson's Dilemma, written just before Murdoch was diagnosed with Alzheimer's disease, were all converted to digital format and analysed using specialised software. (ucl.ac.uk)
  • Her manuscripts thus offer a unique opportunity to explore the effects of the early stages of Alzheimer's disease on spontaneous writing, and raises the possibility of enhancing cognitive tests used to diagnose the disease, for example by comparing correspondence or diary entries collected over someone's life. (ucl.ac.uk)
  • Dame Iris Murdoch was diagnosed with Alzheimer's disease at the age of 76, shortly after the publication of her final novel in 1995. (ucl.ac.uk)
  • A brain scan performed in June 1997 showed profound shrinkage in the part of her brain associated with memory, the hippocampus - a finding typical of Alzheimer's disease. (ucl.ac.uk)
  • John Bayley, Iris Murdoch's husband, says: "Iris donated her brain to medical science to help in the search for a cure for Alzheimer's disease. (ucl.ac.uk)
  • Parkinson's disease (PD) was first described by Dr. James Parkinson in 1817 as a "shaking palsy" [1] is the second most common neurodegenerative disorder after Alzheimer's disease (AD). (irispublishers.com)
  • We performed a 24-week, randomized, placebo-controlled, and blinded study of curcumin for Alzheimer's disease in which there was a 24-week open-label extension. (irispublishers.com)
  • In a trial of curcumin for Alzheimer's disease, we serendipitously observed a dose-dependent trend for decreased complaints of joint pain. (irispublishers.com)
  • Curcumin is a polyphenolic compound derived from the plant Curcuma Long Lin that has been demonstrated to have anti-inflammatory and antioxidant properties as well as efficacy against the pathology of Alzheimer's disease (AD) in animal models [2-4]. (irispublishers.com)
  • Here we report evidence for efficacy of Curcumin in the treatment of joint pain observed serendipitously in a randomized placebo-controlled trial for Alzheimer's disease (AD). (irispublishers.com)
  • With a name like 'Whale's Tale,' this dramatic bicolor Tall Bearded Iris ( Iris germanica ) elicits images of a dark, moody sea and a mysterious whale splashing in its midst. (whiteflowerfarm.com)
  • The iris species as a whole is a remarkably resilient group of plants with few natural insect enemies or diseases. (cdn-iris.ca)
  • Unlike most sources, we ship our iris as bare-root plants in the spring . (oldhousegardens.com)
  • Iris plants are fairly indestructible. (whiteflowerfarm.com)
  • Hemstitched German iris has white, ruffled petals with a blue rim. (dutchbulbs.com)
  • Learn more about growing and enjoying iris at our Iris Newsletter Archives and Bulbs as Cut-Flowers page . (oldhousegardens.com)
  • On March 13, 2020, the United States declared a national emergency to combat coronavirus disease 2019 (COVID-19). (cdc.gov)
  • The 2019 Gordon Research Conference on Tropical Infectious Diseases will present cutting edge research on the most prevalent and medically important tropical infectious and emerging diseases (TIEDs). (grc.org)
  • The 2019 GRC will include disease-focused sessions from Innovation to Global Health Impact for tropical bacterial infections and antibiotic resistance, emerging and re-merging TIEDs with an emphasis in new advances related to host-parasite relationships, novel technologies leading to global impact and lessons learned from the bench to the clinic. (grc.org)
  • The HIV community and response have much to offer to the coronavirus disease 2019 (COVID-19) preparedness and resiliency. (bvsalud.org)
  • Glaucoma is a disease of the eye that develops when the pressure within the eye increases. (petplace.com)
  • Because the ciliary body is located behind the iris, the disease can grow undetected for a longer time than choroidal melanoma or iris melanoma. (cancer.net)
  • Ciliary body melanoma is more likely to spread outside the eye than iris and choroidal melanomas. (cancer.net)
  • Parkinson's disease (PD) is a common neurodegenerative disorder with the pathological hallmark of progressive loss of dopamine neurons in affected brains. (irispublishers.com)
  • More than 40 mutations of LRRK2 have been found in both familial and sporadic forms of PD [8,9], among which, a missense mutation, G2019S, is frequently found in not only familial but also sporadic Parkinson's disease cases [10]. (irispublishers.com)
  • The G2019S mutation enhances kinase activity, suggesting that small molecule LRRK2 kinase inhibitors may be able to block aberrant LRRK2-dependent signaling in Parkinson's disease [11,12]. (irispublishers.com)
  • Bearded irises require well drained soil and a sunny location (6-7 hours plus of direct sunlight per day) . (cdn-iris.ca)
  • Diseases are very likely to occur if the location is shaded or if the soil is wet and poorly drained. (cdn-iris.ca)
  • Irises grow best in a well prepared soil with the ground dug deeply and a fertilizer such as 4-10-12 worked into the bed. (cdn-iris.ca)
  • Generally, bearded iris require a sunny and well drained spot and do best with a soil pH near neutral. (garden.org)
  • Dr Peter Garrard of UCL's Institute of Cognitive Neuroscience says: "Iris Murdoch was known to write only in longhand, with few revisions of passages, sending the completed longhand manuscripts to her publishers with little allowance for editorial interference. (ucl.ac.uk)
  • Iris atrophy in sickle cell disease. (medscape.com)
  • A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. (bvsalud.org)
  • The American Iris Society has classified them into six groups differentiated mainly by height, from the Miniature Dwarf Bearded Iris (up to 8" tall) to the Tall Bearded Iris (27½" tall or more). (whiteflowerfarm.com)
  • The best time to plant new bearded irises or to divide and replant overgrown clumps is in mid to late July and through the month of August . (cdn-iris.ca)
  • Peer reviewers for Emerging Infectious Diseases evaluate manuscripts on EID Manuscript Central , which is a manuscript tracking system that allows authors to submit manuscripts and reviewers to evaluate manuscripts electronically. (cdc.gov)
  • Emerging Infectious Diseases has partnered with Publons to make it easier for peer reviewers to track their contributions. (cdc.gov)
  • Emerging Infectious Diseases thanks the following reviewers for their support through thoughtful, thorough, and timely reviews in 2023. (cdc.gov)
  • This GRC will be held in conjunction with the "Tropical Infectious Diseases" Gordon Research Seminar (GRS). (grc.org)
  • Severe IRIS may threaten a patient's functional status or cause permanent disability or death. (hivguidelines.org)
  • Although many hemoglobinopathies exist, those resulting in proliferative retinopathy are limited to sickle cell disease. (medscape.com)
  • Homozygous sickle cell disease (SS disease), sickle cell C disease (SC disease), and sickle cell-thalassemia disease (S-Thal disease) are common hemoglobinopathies that can present with mild-to-severe proliferative retinal findings. (medscape.com)
  • In 1930, ocular changes associated with sickle cell disease were noted. (medscape.com)
  • In 1959, Lieb and coworkers associated angioid streaks with sickle cell disease. (medscape.com)
  • In 1966, Welch and Goldberg introduced and described much of the modern terminology associated with sickle cell disease with respect to ocular changes. (medscape.com)
  • Patients with sickle cell disease should be well informed of their current and potential long-term complications. (medscape.com)
  • Pathogenesis and treatment of sickle cell disease. (medscape.com)
  • Between 2018 and 2022, EMR countries responded to 166 disease outbreaks, averaging 33 outbreaks annually, and in 2022 alone, some 127 million people needed humanitarian aid, accounting for 38% of the global humanitarian burden (2). (who.int)
  • The wave of legislation adoption in or chronic respiratory disease) by 2025. (who.int)
  • This is the only way to detect lagophthalmos, which accounts for much of the corneal disease in brachycephalic breeds. (vin.com)
  • The Schirmer's tear test should be done to any eye in which there is discharge, signs of inflammation, or corneal disease (there is no contraindication for this procedure). (vin.com)
  • Las características más comunes de este síndrome son el movimiento de las células endoteliales fuera de la córnea hacia el iris que provoca inflamación corneal, distorsión del iris y grados variables de distorsión de la pupila. (bvsalud.org)
  • The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. (bvsalud.org)
  • Clinical and laboratory factors associated with the severity of proliferative sickle cell retinopathy in patients with sickle cell hemoglobin C (SC) and homozygous sickle cell (SS) disease. (medscape.com)
  • German iris are quite hardy and are resistant to drought, disease, and insects. (dutchbulbs.com)
  • Like most bearded irises, it's quite hardy and resistant to drought, disease, and insects. (brecks.com)
  • The discovery deepens our understanding of m6A biology and stress granule formation, with implications for neurodegenerative diseases. (medindia.net)
  • The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)
  • Diabetes mellitus is a disease of the pancreas related to insufficient amounts of insulin production. (petplace.com)
  • Dogs affected with this condition will exhibit some combination of the following: Microphthalmia, eccentric pupils, coloboma or other irregularities of the iris, lens luxation, cataract, retinal dysplasia or detachment, persistent pupillary membrane, equatorial staphyloma and lack of a tapetum. (workingaussiesource.com)
  • The metaphor is evidently drawn from the solid opaque look of the iris, when affected by cataract or some similar disease. (studylight.org)
  • If you have a large enough garden possibly you may want to create flower beds exclusively for irises so that they are treated to their optimum growing conditions. (cdn-iris.ca)
  • Alphabetical iris check list, 1949. (upenn.edu)
  • Apart from that, there isn't too much to do for iris with the possible exception of checking them for frost heaving during the winter. (garden.org)
  • The potential cure for aniridia, a rare eye disease that limits vision in humans, has now been developed by a team of Canadian scientists. (medindia.net)
  • Chronic Kidney Disease (CKD): IRIS Stages 3, 4. (viovet.co.uk)
  • Patients suffering from the disease do not have an iris (the coloured ring around the pupil), and suffer many other eye abnormalities. (medindia.net)
  • iris) and a pupil that is not in the center of the eye. (medlineplus.gov)
  • Agrupación de tres afecciones estrechamente vinculadas: iris nevus o Síndrome de Cogan-Reese, Síndrome de Chandler y atrofia del iris esencial (progresiva). (bvsalud.org)
  • Sebaceous Adenitis is a skin disease that is genetically inherited The exact cause is unknown, but it may be caused by an attack of the immune system against the sebaceous glands. (petplace.com)
  • It tended toward greater genetic diversity within individual dogs and therefore lessened the likelihood that bad genes for things like eye disease would match up. (workingaussiesource.com)
  • Left ventricular acquired apical aneurysms are the result of chronic damage of the myocardium and are associated with many disease conditions in people, including coronary artery disease and cardiomyopathy. (bvsalud.org)
  • COL4A1 -related brain small-vessel disease is part of a group of conditions called the COL4A1 -related disorders. (medlineplus.gov)
  • Charache S. Eye disease in sickling disorders. (medscape.com)
  • Remove any browning leaves this summer and clean out and destroy all the iris debris this fall to minimize disease problems. (garden.org)
  • For helpful advice on the most common ones - iris borer (which is only a problem east of the Rockies), leaf spot, and root rot - see the excellent Iris Garden website sponsored by the iris societies of New England. (oldhousegardens.com)
  • One of the most common causes of death in domesticated felines is chronic kidney disease (CKD). (slu.se)
  • Iris melanoma is the least common type of uveal melanoma. (cancer.net)
  • Of the non-merle related diseases, cataracts and iris coloboma are most common, followed by CEA (Collie Eye Anomaly). (workingaussiesource.com)
  • This guideline was developed by the New York State Department of Health AIDS Institute (NYSDOH AI) for primary care providers and other practitioners who manage immune reconstitution inflammatory syndrome (IRIS) in patients with HIV. (hivguidelines.org)
  • Emphasize that antiretroviral therapy (ART) should not be interrupted in patients with IRIS except in life-threatening cases. (hivguidelines.org)
  • and 3) The ability of primary care providers and other clinicians in New York State to manage IRIS is key to the successful treatment of patients with HIV. (hivguidelines.org)
  • This early complication is seen most often within the first 8 weeks of therapy in patients with advanced HIV disease. (hivguidelines.org)
  • Mild IRIS resolves over time in most patients, and symptomatic treatment is often sufficient. (hivguidelines.org)
  • IRIS, which is also known as immune restoration disease, refers to a disease- or pathogen-specific inflammatory response that may be triggered after ART initiation in treatment-naive patients, after re-initiation of ART, or after a change to a more effective ART regimen in patients who fail to achieve viral suppression. (hivguidelines.org)
  • International randomized study of interferon vs STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase treated with imatinib [abstract]. (medscape.org)
  • STI refers to infection with a pathogen that is transmitted through sexual contact, while STD refers to the recognizable disease that develops as a result of the STI. (wildirismedicaleducation.com)
  • Refers to the worsening of a previously diagnosed disease after ART initiation. (hivguidelines.org)
  • SEA POWER (Keppel 1999) A Tall Bearded (TB) iris, 38 inches height, Awards: Dykes Medal winner 2006, Wister Medal 2005, AM 2003, HM 2001. (cdn-iris.ca)
  • Progressive Retinal Degeneration is a disease that causes nerve cells at the back of the eye to degenerate. (petplace.com)
  • Stage 1 kidney disease is early, and stage 4 is late. (pethealthnetwork.com)
  • The proportion of infectious disease-related visits was four times higher during the early pandemic period. (cdc.gov)
  • Finch NC, Geddes RF, Syme HM, Elliott J. Fibroblast Growth Factor 23 (FGF-23) Concentrations in Cats with Early Nonazotemic Chronic Kidney Disease (CKD) and in Health Geriatric Cats. (idexx.com)
  • Traditionally, bearded iris are divided in early to mid summer and replanted immediately. (garden.org)
  • Iris recognition was developed in the early 1990s by John Daugman at the University of Cambridge. (fidis.net)
  • Dietary therapy is the mainstay of management of chronic kidney disease (CKD) is cats. (vin.com)
  • Cats were enrolled if they were in IRIS stage 1-2 CKD. (vin.com)
  • 4 cats on control food were dismissed for loss of body condition, loss of appetite, and/or progressive renal disease. (vin.com)
  • A new method for managing and monitoring phosphorous overload in chronic kidney disease-now included in IRIS treatment recommendations for CKD in cats. (idexx.com)
  • Relationship between Plasma Fibroblast Growth Factor-23 concentration and Survival Time in Cats with Chronic Kidney Disease. (idexx.com)
  • Bearded irises: how to grow. (cdn-iris.ca)
  • Bearded irises will usually grow adequately with very minimal attention, however with a little attention and assistance they can become outstanding centers of attention in your garden. (cdn-iris.ca)
  • As bearded irises grow vigorously during the first two months of the season, now is the time to apply a complete fertilizer such as 4-10-12. (cdn-iris.ca)
  • The resolution recommends that Member States take steps towards achieving effective, efficient and integrated national disease surveillance systems as an integral part of their national health information systems, and be connected to the global disease surveillance systems by the end of 2025. (who.int)
  • COL4A1 -related brain small-vessel disease is a rare condition, although the exact prevalence is unknown. (medlineplus.gov)
  • Allergic dermatitis or Atopy is an itchy skin disease of animals that is caused by an allergy to substances in the environment. (petplace.com)
  • As it says on the IRIS website , "SDMA concentrations in blood (plasma or serum) may be a more sensitive biomarker of renal function than blood creatinine concentrations. (pethealthnetwork.com)
  • ed. note: C.A.Sharp is the president of the Australian Shepherd Genetics Institute , an organization 'dedicated to the increase and diffusion of knowledge of genetics in the Australian Shepherd, and the inherited diseases from which it sometimes suffers. (workingaussiesource.com)
  • She is a science writer and an internationally recognized lay expert on canine genetics and hereditary diseases. (workingaussiesource.com)
  • On tall, strong stems, its primrose-and-cream standards over old-rose, almost-pink falls make it an iris that our garden visitors always notice and admire. (oldhousegardens.com)
  • Iris range from timid and inconspicuous wildlings to the splendid and extravagant Tall Bearded Iris, which create striking vertical highlights in the late spring border. (whiteflowerfarm.com)
  • Hypertrophic Osteodystrophy (HOD) - is a disease of young, large- and giant-breed dogs causing lameness due to bone inflammation. (petplace.com)
  • At first the idea sounds no different, and no less ridiculous, than treating liver disease by rubbing the foot, or diagnosing heart disease by the pattern of colors in the iris. (theness.com)
  • The chosen habitats of Iris range from standing water to formal borders, and there is scarcely a color or combination of colors that can't be found. (whiteflowerfarm.com)