A disorder of the buccal mucosa resembling early leukoplakia, characterized by the presence of filmy opalescence of the mucosa in the early stages to a whitish gray cast with a coarsely wrinkled surface in the later stages, associated with intracellular edema of the spinous or malpighian layer. (Dorland, 27th ed)

Leukoedema: a review of the literature. (1/1)

Leukoedema, a grayish-white lesion of the oral mucosa in humans, was once thought to be a probable precursor to leukoplakia. Clinical examination differentiates leukoedema from leukoplakia, lichen planus, white sponge nevus, and pathomimia morsicatio buccarum. Prevalence rates vary greatly in different countries and in different ethnic groups. For many years, leukoedema was alleged to occur only in adult populations until Martin and Crump found this lesion in children and youth. There is a definite predilection for this lesion in black Americans. Although the etiology is unknown, it has been suggested that leukoedema develops in areas of local irritation. This article reviews the literature related to the prevalence of leukoedema and correlates the independent findings, which might pertain to its etiology.  (+info)

Oral leukoedema, also known as leukoedema diffusa, is a benign and common condition that affects the oral mucosa. It is characterized by a symmetrical, milky white or opalescent appearance of the buccal mucosa (the lining of the inner cheeks) due to the accumulation of fluid in the connective tissue beneath the epithelium.

The exact cause of oral leukoedema remains unclear, but it is not associated with any systemic diseases or harmful habits such as smoking. It is more prevalent in African Americans and Asians compared to Caucasians. The condition typically presents as a symmetrical, diffuse, and bilateral involvement of the buccal mucosa, although other areas of the oral cavity can also be affected.

Oral leukoedema does not cause any symptoms or discomfort, and it is usually an incidental finding during routine dental or medical examinations. The condition may occasionally be mistaken for other oral conditions such as oral candidiasis (thrush) or lichen planus; however, these conditions can be differentiated through clinical examination and diagnostic tests if necessary. No specific treatment is required for oral leukoedema, and the condition does not pose any health risks or lead to malignant changes.

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