Lipoblastoma
Neoplasms, Adipose Tissue
Lipoma
Liposarcoma
Paediatric lipoblastoma in the head and neck: three cases and review of literature. (1/4)
(+info)Giant omental lipoblastoma and CD56 expression. (2/4)
(+info)Cervical hibernoma and lipoblastomatosis. (3/4)
(+info)Myxoid lipoblastoma. (4/4)
A rapidly growing soft tissue mass in the axilla of an infant raises the suspicion of a lipoblastoma or a liposarcoma. Excisional/incisional biopsy is vital in confirming the diagnosis and hence avoiding aggressive extirpation. This case report highlights the role of histopathology and immunohistochemistry as the gold standard in differentiating a lipoblastoma from a liposarcoma. In some cases where the histopathology is inconclusive, genetic rearrangement of the PLAG1 (pleomorphic adenoma gene 1) oncogene on chromosome 8q12 helps in confirming the diagnosis of lipoblastoma. (+info)Lipoblastoma is a relatively rare, benign tumor that originates from fetal fat tissue. It typically occurs in children under the age of 3, with around 90% of cases diagnosed before the age of 7. These tumors usually grow in the soft tissues of the extremities, trunk, or head and neck region. Lipoblastomas are well-circumscribed, meaning they have a clear border, and they do not typically invade surrounding tissues.
The tumor is composed of immature fat cells called lipoblasts, which are normally found during fetal development but disappear after birth. The presence of these cells in a lipoblastoma suggests that the tumor represents a type of abnormal fat tissue growth.
Lipoblastomas can be classified into two types:
1. Lipoblastoma simplex: This is the more common form, accounting for around 75% of cases. It is a localized tumor that does not spread to other parts of the body.
2. Lipoblastomatosis: This type is less common and tends to be more invasive. It consists of multiple, interconnected lipoblastomas that can grow and infiltrate surrounding tissues.
Treatment for lipoblastoma typically involves surgical removal of the tumor. Recurrence after surgery is possible but relatively uncommon, especially if wide margins are achieved during resection. Malignant transformation of a lipoblastoma into a liposarcoma, a type of cancerous fat tissue tumor, is extremely rare.
Neoplasms in adipose tissue refer to abnormal and excessive growths of cells that form tumors within the fatty connective tissue. These neoplasms can be benign or malignant (cancerous). Benign neoplasms, such as lipomas, are slow-growing and typically do not spread to other parts of the body. Malignant neoplasms, on the other hand, are cancerous and can invade surrounding tissues and spread to distant sites in the body (metastasis). An example of a malignant neoplasm in adipose tissue is liposarcoma. It's important to note that while some neoplasms may not cause any symptoms, others can cause pain, swelling or other uncomfortable sensations, and therefore should be evaluated by a medical professional for proper diagnosis and treatment.
A lipoma is a common, benign (non-cancerous) soft tissue growth. It is composed of adipose or fatty tissue and typically found just beneath the skin, but they can also occur deeper within the body. Lipomas are usually round, moveable, and painless, although they may cause discomfort if they grow large enough to put pressure on nearby nerves or if they're located in a sensitive area. They generally grow slowly over time. Surgical removal is an option if the lipoma becomes bothersome or grows significantly in size. It's important to note that while lipomas are typically harmless, any new lumps or bumps should be evaluated by a healthcare professional to confirm the diagnosis and rule out other more serious conditions.
Liposarcoma, myxoid type, is a specific subtype of liposarcoma, which is a malignant (cancerous) tumor that develops from fat cells. Myxoid liposarcoma is characterized by the presence of a gel-like substance in the tumor tissue. It usually occurs in deep soft tissues, such as muscles, tendons, and ligaments, and can be found in various parts of the body, but it most commonly affects the thigh.
Myxoid liposarcoma tends to grow slowly and has a better prognosis compared to other subtypes of liposarcoma. However, it can still metastasize (spread) to other parts of the body, such as the lungs, bones, and lymph nodes. Treatment typically involves surgical removal of the tumor, with radiation therapy and/or chemotherapy used in some cases to help reduce the risk of recurrence or spread.
It's important to note that while I strive to provide accurate information, my responses should not be used as a substitute for professional medical advice, diagnosis, or treatment.
Liposarcoma is a type of soft tissue sarcoma, which is a cancer that develops in the soft tissues of the body, such as fat, muscle, nerves, blood vessels, and fibrous tissues. Specifically, liposarcoma arises from fat cells (adipocytes) or their precursors.
There are several subtypes of liposarcoma, which differ in their appearance under the microscope, genetic features, and clinical behavior. These include well-differentiated, dedifferentiated, myxoid, round cell, and pleomorphic liposarcomas. The most common sites for liposarcoma are the thigh, retroperitoneum (the area behind the abdominal cavity), and the buttock.
Liposarcomas can grow slowly or rapidly, and they may spread to other parts of the body (metastasize) through the bloodstream or lymphatic system. Treatment typically involves surgical removal of the tumor, often followed by radiation therapy and/or chemotherapy. The prognosis for liposarcoma depends on several factors, including the type and grade of the tumor, its size and location, and whether it has spread to other parts of the body.
Lipoblastoma
Myxoid lipoblastoma
Lipoblastomatosis
Adipocyte
PLAG1
HAS2
Lipoblast
List of skin conditions
Myxoid tumor
International Classification of Diseases for Oncology
Lipoblastoma - Wikipedia
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Lipoblastomatosis4
- A localized, superficial, singular, well circumscribed or encapsulated variant is designated as lipoblastoma whereas diffuse, multi-centric, non-encapsulated, infiltrative variant is nomenclated as lipoblastomatosis [2]. (lupinepublishers.com)
- Demography and characteristics of lipoblastomatosis is essentially similar to lipoblastoma [1,2]. (lupinepublishers.com)
- Lipoblastoma and lipoblastomatosis are commonly discerned in infants or young children beneath (lupinepublishers.com)
- Lipoblastoma (also called lipoblastomatosis) develops in babies and young children. (cancer.ca)
Tumor9
- Lipoblastoma is a rare benign tumor of the soft tissue occurring predominantly during the first two years of life. (elsevierpure.com)
- Our patient's lipoblastoma did not demonstrate the signal characteristics of a fatty tumor on MRI. (elsevierpure.com)
- Lipoblastoma is a rare benign tumor of adipose tissue seen almost always in infanthood and early childhood. (erdogan.edu.tr)
- Lipoblastoma is a tumor with good prognosis despite its potential for local invasion and rapid growth. (erdogan.edu.tr)
- Lipoblastoma is a rare benign tumor with 80â€"90% occurring in children less than 3 years of age and 40% occurring in children less than 1 year of age. (koreamed.org)
- Lipoblastoma is a rare mesenchymal tumor occurring primarily in pediatric patients and formed by lipoblasts that proliferate after the postnatal period. (rbcp.org.br)
- O lipoblastoma é um tumor mesenquimal raro, composto de lipoblastos que continuam sua proliferação após o período pós-natal e que acometem, predominantemente, a população pediátrica. (rbcp.org.br)
- The term "lipoblastoma" is used to describe a tumor of this cell type. (ipfs.io)
- Our presentation will include imaging examples utilizing multiple modalities demonstrating examples of pancreaticoblastoma , immature lipoblastoma, neuroblastoma, hepatoblastoma, a case of biopsy confirmed small cell undifferentiated renal rhabdoid tumor, and a unique case of pleuropulmonary blastoma. (abstractarchives.com)
Benign lipoblastoma4
- Malignant metamorphoses or distant metastasis of benign lipoblastoma is unknown [3,4]. (lupinepublishers.com)
- The excised mass was diagnosed pathologically as a benign lipoblastoma. (erdogan.edu.tr)
- In the literature, 4 types of thoracic wall lipoblastomas have been reported, but thoracic wall resection has not been applied in any benign lipoblastoma case. (erdogan.edu.tr)
- To the best of our knowledge, the only benign lipoblastoma case in which a thoracic wall resection was carried out, with its clinical and histopathologic specifications alongside that in the literature, is presented here for the first time. (erdogan.edu.tr)
Myxoid3
- Myxoid lipoblastoma, a cutaneous condition characterized by excess mucin Grossly, it has a pale yellow, myxoid cut surface with small cystic foci. (wikipedia.org)
- Lipoblastoma can simulate foetal adipose tissue aggregates or a myxoid liposarcoma. (lupinepublishers.com)
- FNA biopsies of a lipoblastoma contain multivacuolated lipoblasts, myxoid areas, and a plexiform capillary network. (medscape.com)
Lipoblasts2
- Lipoblastoma is an exceptional, benign, lobulated, mesenchymal neoplasm arising from embryonal adipose tissue cells or lipoblasts or immature adipocytes. (lupinepublishers.com)
- Jaffe described lipoblastoma as an atypical lipoma with cellular constituents simulating embryonic fat or lipoblasts, in 1926. (lupinepublishers.com)
Adipose6
- As lipoblastoma arises from embryonic adipose tissue, it is additionally nomenclated as "embryonic lipoma or foetal or embryonal lipoblastoma" [1]. (lupinepublishers.com)
- A predominantly lobulated, well circumscribed, encapsulated tumefaction simulating foetal adipose tissue, lipoblastoma is commonly situated within subcutaneous tissue. (lupinepublishers.com)
- Essentially comprised of immature, persistent, embryonic adipose tissue which proliferates rapidly within the post natal period, lipoblastoma can configure an enlarged tumefaction wherein the variable tumour magnitude can extend up to 25 centimetres [3,4]. (lupinepublishers.com)
- As a lobulated, mesenchymal neoplasm comprised of embryonal or foetal adipose tissue, lipoblastoma, characteristically demonstrates a benign biological behaviour, preliminary discernment, male predominance and brisk tumour evolution. (lupinepublishers.com)
- Lipoblastoma is commonly observed within sites of persistent immature adipose tissue. (lupinepublishers.com)
- Lipoblastoma is the least known of adipose tumours. (web.app)
Lipoma1
- Non-resected lipoblastoma generally matures into lipoma with prominent fibrous tissue septa [4]. (lupinepublishers.com)
Prognosis1
- Nevertheless, despite rapid progression and localized tumour infiltration of abutting anatomic structures, lipoblastoma delineates a superior prognosis [3,4]. (lupinepublishers.com)
Subcutaneous1
- Lipoblastoma arises as a gradually progressive, painless, superficial, subcutaneous, soft tissue nodule or a well circumscribed mass wherein an estimated 75% tumefaction appear upon the left side. (lupinepublishers.com)
Neck1
- Lipoblastoma arises upon the trunk in nearly 10% to 60% subjects or extremities in roughly 40% to 45% individuals whereas tumefaction of the head and neck is exceptional. (lupinepublishers.com)
Chest2
- Lipoblastoma situated within the chest wall can exhibit cough, dyspnoea, airway obstruction with impaired airway clearance and predisposition to respiratory infections. (lupinepublishers.com)
- Chest wall lipoblastoma in a seven-month. (erdogan.edu.tr)
Soft1
- We report here the application of MRI and ultrasound to the detection of a soft tissue lipoblastoma. (elsevierpure.com)
Literature1
- However, cases of pleural, thoracic wall, and pulmonary lipoblastoma have also been reported in the literature. (erdogan.edu.tr)
Mesenteric lipoblastoma3
- We present a case of giant mesenteric lipoblastoma in a girl, reviewing and discussing pertinent literature. (hindawi.com)
- Scientific databases (PubMed, Medline, Cochrane Collaboration, and Scopus) were screened looking for studies reporting on mesenteric lipoblastoma in children. (hindawi.com)
- 10. Giant mesenteric lipoblastoma in a 4-year-old child. (nih.gov)
Benign1
- title={Toraks duvarında benign lipoblastoma olgusu}, congress name={2. (erdogan.edu.tr)
Clinicopathologic1
- Coffin CM, Lowichik A, Putnam A. Lipoblastoma (LPB): a clinicopathologic and immunohistochemical analysis of 59 cases. (indexedjournals.info)
Diagnosis1
- 7. Cervical lipoblastoma: an uncommon diagnosis of neck mass. (nih.gov)
Rare3
- We present a case of a rare giant lipoblastoma arising from the mesentery of a 6-year-old girl, with a history of postprandial abdominal pain. (hindawi.com)
- 3. Lipoblastoma in head and neck--a rare childhood tumour. (nih.gov)
- 13. Lipoblastoma: a rare cervical mass in childhood. (nih.gov)
Review6
- 4. Lipoblastoma of the neck: a case report and literature review. (nih.gov)
- 5. Cervical lipoblastoma: case report, review of literature, and genetic analysis. (nih.gov)
- 15. Pediatric lipoblastoma in the head and neck: a systematic review of 48 reported cases. (nih.gov)
- 16. Two young girls with lipoblastoma and a review of the literature. (nih.gov)
- 18. A thoracic wall lipoblastoma in a 3-month-old infant: A case report and review of the literature. (nih.gov)
- Varied Presentations of Pediatric Lipoblastoma: Case Series and Review of the Literature. (bu.edu)