Meningioma
Meningeal Neoplasms
Arachnoid
Skull Base Neoplasms
Brain Neoplasms
Dura Mater
Genes, Neurofibromatosis 2
Magnetic Resonance Imaging
Neuroma, Acoustic
Optic Nerve Neoplasms
Hemangiopericytoma
Ear Neoplasms
Neurofibromatosis 2
Cerebral Ventricle Neoplasms
Neurilemmoma
Tomography, X-Ray Computed
Meninges
Chromosomes, Human, Pair 22
Neurofibromin 2
Encyclopedias as Topic
Fibroma, Desmoplastic
Hemangioendothelioma
Radiosurgery
Treatment Outcome
Trigeminal Neuralgia
SPARC: a potential diagnostic marker of invasive meningiomas. (1/1193)
SPARC, a secreted, extracellular matrix-associated protein implicated in the modulation of cell adhesion and migration, was evaluated as a marker for invasive meningiomas. Although the majority of meningiomas are clinically and morphologically benign, approximately 10% progress into atypical and malignant tumors, according to the standard criteria. However, a subset of meningiomas presents as histomorphologically benign tumors (WHO grade I), but they are clinically invasive. It has been suggested that these tumors should be classified as malignant, and that the patients may require adjuvant therapy and closer follow up. Unfortunately, a significant number of these tumors may not be recognized because the surgical specimen used to assess the grade of a tumor lacks the infiltrative interface with the brain, which is currently necessary to determine its invasive character. Therefore, a marker of heightened invasiveness would greatly facilitate the identification of this subset of patients. In this study, the immunohistochemical expression of SPARC in benign, noninvasive primary meningiomas was compared with its expression in invasive, aggressive, primary and recurrent meningiomas. SPARC was not expressed in the 9 benign, noninvasive tumors, but was highly expressed in the 20 invasive tumors, regardless of the grade. The findings suggest that SPARC is a potential diagnostic marker of invasive meningiomas and is capable of distinguishing the histomorphologically benign noninvasive from the histomorphologically benign but invasive meningiomas, in the absence of the infiltrative interface. (+info)Hemangioblastoma mimicking tentorial meningioma: preoperative embolization of the meningeal arterial blood supply--case report. (2/1193)
A 72-year-old male presented with a primary hemangioblastoma of the posterior fossa with unusual dural attachment and meningeal arterial blood supply from the external carotid artery and marginal tentorial artery. Preoperative embolization facilitated complete resection of the tumor with no resultant neurological deficit. Hemangioblastoma must be included in the differential diagnosis of tumors with dural involvement. Preoperative embolization is very useful in such tumors. (+info)Cerebral veins: comparative study of CT venography with intraarterial digital subtraction angiography. (3/1193)
BACKGROUND AND PURPOSE: Our objective was to compare the reliability of CT venography with intraarterial digital subtraction angiography (DSA) in imaging cerebral venous anatomy and pathology. METHODS: In 25 consecutive patients, 426 venous structures were determined as present, partially present, or absent by three observers evaluating CT multiplanar reformatted (MPR) and maximum intensity projection (MIP) images. These results were compared with the results from intraarterial DSA and, in a second step, with the results of an intraobserver consensus. In addition, pathologic conditions were described. RESULTS: Using DSA as the standard of reference, MPR images had an overall sensitivity of 95% (specificity, 19%) and MIP images a sensitivity of 80% (specificity, 44%) in depicting the cerebral venous anatomy. On the basis of an intraobserver consensus including DSA, MPR, and MIP images (415 vessels present), the sensitivity/specificity was 95%/91% for MPR, 90%/100% for DSA, and 79%/91% for MIP images. MPR images were superior to DSA images in showing the cavernous sinus, the inferior sagittal sinus, and the basal vein of Rosenthal. Venous occlusive diseases were correctly recognized on both MPR and MIP images. Only DSA images provided reliable information of invasion of a sinus by an adjacent meningioma. CONCLUSION: CT venography proved to be a reliable method to depict the cerebral venous structures. MPR images were superior to MIP images. (+info)A new technique of surface anatomy MR scanning of the brain: its application to scalp incision planning. (4/1193)
BACKGROUND AND PURPOSE: Surface anatomy scanning (SAS) is an established technique for demonstrating the brain's surface. We describe our experience in applying SAS with superposition of MR venograms to preoperative scalp incision planning. METHODS: In 16 patients, scalp incision planning was done by placing a water-filled plastic tube at the intended incision site when we performed SAS using half-Fourier single-shot fast spin-echo sequences. Two-dimensional phase-contrast MR angiograms were obtained to demonstrate the cortical veins and then superimposed upon the SAS images. The added images were compared with surgical findings using a four-point grading scale (0 to 3, poor to excellent). RESULTS: In each case, neurosurgeons could easily reach the lesion. Surgical findings correlated well with MR angiogram-added SAS images, with an average score of 2.56. CONCLUSION: Our simple technique is a useful means of preoperatively determining brain surface anatomy and can be used to plan a scalp incision site. (+info)In vivo hydrogen-1 magnetic resonance spectroscopy study of human intracranial tumors. (5/1193)
OBJECTIVE: To investigate the metabolic changes, pathological state and histological types of intracranial tumors with hydrogen-1 magnetic resonance spectroscopy (H-1 MRS). METHODS: Thirteen patients with intracranial tumors were studied with localized proton magnetic resonance spectroscopy (H-1MRS), in vivo. All spectra were obtained with a 2.0 T whole body MR imaging system. RESULTS: All the spectra of these tumors exhibited high ratios of choline (Cho)/creatine (Cr) and Cho/N-acetyl aspartate (NAA), and histologically different tumors showed obvious variations in the metabolite ratios. Significant differences of Cho/Cr ratio were found between meningiomas and astrocytomas by statistical evaluation. The spectra obtained after operation were remarkably different from those before operation. CONCLUSION: H-1 MRS can serve as a non-invasive clinical test for therapeutic and prognostic uses for intracranial tumors. (+info)NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas. (6/1193)
Formation of meningiomas and their progression to malignancy may be a multi-step process, implying accumulation of genetic mutations at specific loci. To determine the relationship between early NF2 gene inactivation and the molecular mechanisms that may contribute to meningioma tumor progression, we have performed deletion mapping analysis at chromosomes 1, 14 and 22 in a series of 81 sporadic meningiomas (54 grade I (typical), 25 grade II (atypical) and two grade III (anaplastic)), which were also studied for NF2 gene mutations. Single-strand conformational polymorphism analysis was used to identify 11 mutations in five of the eight exons of the NF2 gene studied. All 11 tumors displayed loss of heterozygosity (LOH) for chromosome 22 markers; this anomaly was also detected in 33 additional tumors. Twenty-nine and 23 cases were characterized by LOH at 1p and 14q, respectively, mostly corresponding to aggressive tumors that also generally displayed LOH 22. All three alterations were detected in association in seven grade II and two grade III meningiomas, corroborating the hypothesis that the formation of aggressive meningiomas follows a multi-step tumor progression model. (+info)Clinical features and outcomes in patients with non-acoustic cerebellopontine angle tumours. (7/1193)
OBJECTIVES: Non-acoustic tumours of the cerebellopontine angle differ from vestibular schwannomas in their prevalence, clinical features, operative management, and surgical outcome. These features were studied in patients presenting to the regional neuro-otological unit. METHODS: A retrospective analysis of clinical notes identified 42 patients with non-acoustic tumours of the cerebellopontine angle. Data were extracted regarding presenting clinical features, histopathological data after surgical resection, surgical morbidity and mortality, and clinical outcome (mean 32 months follow up). RESULTS: The study group comprised 25 meningiomas (60%), 12 epidermoid cysts/cholesteatomata (28%), and five other tumours. In patients with meningiomas, symptoms differed considerably from patients presenting with vestibular schwannomas. Cerebellar signs were present in 52% and hearing loss in only 68%. Twenty per cent of patients had hydrocephalus at the time of diagnosis. After surgical resection, normal facial nerve function was preserved in 75% of cases. In the epidermoid group, fifth, seventh, and eighth nerve deficits were present in 42%, 33%, and 66% respectively. There were no new postoperative facial palsies. There were two recurrences (17%) requiring reoperation. Overall, there were two perioperative deaths from pneumonia and meningitis. CONCLUSIONS: Patients with non-acoustic lesions of the cerebellopontine angle often present with different symptoms and signs from those found in patients with schwannomas. Hearing loss is less prevalent and cerebellar signs and facial paresis are more common as presenting features. Hydrocephalus is often present in patients presenting with cerebellopontine angle meningiomas. Non-acoustic tumours can usually be resected with facial nerve preservation. (+info)Role of p53 gene mutation in tumor aggressiveness of intracranial meningiomas. (8/1193)
The mutations that occur in the p53 tumor suppressor gene have been studied in various human malignant tumors. However, little is known about this gene in meningiomas. To investigate the relationship and frequency of p53 gene mutations, the p53 polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and immunohistochemical study were performed on the 41 intracranial meningiomas (21 benign, 11 atypical, and 9 malignant). The higher the p53 protein expression rate, the poorer the histologic grade (9.5%, 72.7%, and 88.9% in benign, atypical and malignant meningioma, respectively) (p=0.000). The p53 protein expression rate was higher in recurrent meningioma (71.4%) than in nonrecurrent meningioma (10.5%) (p=0.002). PCR-SSCP method was performed in positive p53 protein immunoreactivity cases. p53 gene mutation rate was higher in the atypical (62.5%) and malignant (25%) meningiomas than in the benign meningioma (0%) (p=0.232). Also, the rate was higher in recurrent menigioma (20%) than in nonrecurrent meningioma (0%) (o=0.495). Among five to eight exons of the p53 gene, the mutation was observed on exon 7 more frequently. In conclusion, p53 immunoreactivity and p53 gene mutation are closely correlated with histologic grade and histologic atypia of intracranial meningiomas. p53 gene mutation would be considered as a useful marker to detect the progression of intracranial meningiomas. (+info)A meningioma is a type of slow-growing tumor that forms on the membranes (meninges) surrounding the brain and spinal cord. It's usually benign, meaning it doesn't spread to other parts of the body, but it can still cause serious problems if it grows and presses on nearby tissues.
Meningiomas most commonly occur in adults, and are more common in women than men. They can cause various symptoms depending on their location and size, including headaches, seizures, vision or hearing problems, memory loss, and changes in personality or behavior. In some cases, they may not cause any symptoms at all and are discovered only during imaging tests for other conditions.
Treatment options for meningiomas include monitoring with regular imaging scans, surgery to remove the tumor, and radiation therapy to shrink or kill the tumor cells. The best treatment approach depends on factors such as the size and location of the tumor, the patient's age and overall health, and their personal preferences.
Meningeal neoplasms, also known as malignant meningitis or leptomeningeal carcinomatosis, refer to cancerous tumors that originate in the meninges, which are the membranes covering the brain and spinal cord. These tumors can arise primarily from the meningeal cells themselves, although they more commonly result from the spread (metastasis) of cancer cells from other parts of the body, such as breast, lung, or melanoma.
Meningeal neoplasms can cause a variety of symptoms, including headaches, nausea and vomiting, mental status changes, seizures, and focal neurological deficits. Diagnosis typically involves imaging studies (such as MRI) and analysis of cerebrospinal fluid obtained through a spinal tap. Treatment options may include radiation therapy, chemotherapy, or surgery, depending on the type and extent of the tumor. The prognosis for patients with meningeal neoplasms is generally poor, with a median survival time of several months to a year.
The arachnoid is one of the three membranes that cover the brain and the spinal cord, known as the meninges. It is located between the dura mater (the outermost layer) and the pia mater (the innermost layer). The arachnoid is a thin, delicate membrane that is filled with cerebrospinal fluid, which provides protection and nutrition to the central nervous system.
The arachnoid has a spider-web like appearance, hence its name, and it is composed of several layers of collagen fibers and elastic tissue. It is highly vascularized, meaning that it contains many blood vessels, and it plays an important role in regulating the flow of cerebrospinal fluid around the brain and spinal cord.
In some cases, the arachnoid can become inflamed or irritated, leading to a condition called arachnoiditis. This can cause a range of symptoms, including pain, muscle weakness, and sensory changes, and it may require medical treatment to manage.
Skull neoplasms refer to abnormal growths or tumors that develop within the skull. These growths can be benign (non-cancerous) or malignant (cancerous). They can originate from various types of cells, such as bone cells, nerve cells, or soft tissues. Skull neoplasms can cause various symptoms depending on their size and location, including headaches, seizures, vision problems, hearing loss, and neurological deficits. Treatment options include surgery, radiation therapy, and chemotherapy. It is important to note that a neoplasm in the skull can also refer to metastatic cancer, which has spread from another part of the body to the skull.
Hyperostosis is a medical term that refers to an excessive growth or abnormal thickening of bone tissue. It can occur as a result of various conditions, such as inflammation, injury, or genetic disorders. The extra bone growth can cause pain, stiffness, and limited mobility in the affected area. In some cases, hyperostosis can also lead to deformities and other complications.
There are several types of hyperostosis, including:
1. Diffuse idiopathic skeletal hyperostosis (DISH): This is a condition that affects the spine, causing calcification and stiffening of the ligaments and bone spurs to form along the edges of the vertebrae. It is often asymptomatic but can cause pain and stiffness in some cases.
2. Flat bone hyperostosis: This type of hyperostosis affects the flat bones of the body, such as the skull, ribs, and pelvis. It can be caused by various conditions, including Paget's disease, fibrous dysplasia, and certain types of cancer.
3. Focal hyperostosis: This refers to localized areas of bone overgrowth that can occur in response to injury, infection, or inflammation. Examples include heterotopic ossification (the formation of bone in soft tissues) and Freiberg's infarction (a condition that affects the joint surface of the metatarsal bones in the foot).
4. Hyperostosis frontalis interna: This is a benign condition that causes thickening of the inner table of the frontal bone in the skull. It is more common in women and often asymptomatic but can cause headaches and other symptoms in some cases.
Treatment for hyperostosis depends on the underlying cause and severity of the condition. In some cases, no treatment may be necessary. However, if the condition causes pain or limits mobility, various treatments may be recommended, such as medication, physical therapy, or surgery.
Skull base neoplasms refer to abnormal growths or tumors located in the skull base, which is the region where the skull meets the spine and where the brain connects with the blood vessels and nerves that supply the head and neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells in this area, including bone, nerve, glandular, and vascular tissue.
Skull base neoplasms can cause a range of symptoms depending on their size, location, and growth rate. Some common symptoms include headaches, vision changes, hearing loss, facial numbness or weakness, difficulty swallowing, and balance problems. Treatment options for skull base neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The specific treatment plan will depend on the type, size, location, and stage of the tumor, as well as the patient's overall health and medical history.
The cerebellopontine angle (CPA) is a narrow space located at the junction of the brainstem and the cerebellum, where the pons and cerebellum meet. This region is filled with several important nerves, blood vessels, and membranous coverings called meninges. The CPA is a common site for various neurological disorders because it contains critical structures such as:
1. Cerebellum: A part of the brain responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
2. Pons: A portion of the brainstem that plays a role in several vital functions, including facial movements, taste sensation, sleep regulation, and respiration.
3. Cranial nerves: The CPA is home to the following cranial nerves:
* Vestibulocochlear nerve (CN VIII): This nerve has two components - cochlear and vestibular. The cochlear part is responsible for hearing, while the vestibular part contributes to balance and eye movement.
* Facial nerve (CN VII): This nerve controls facial expressions, taste sensation in the anterior two-thirds of the tongue, salivary gland function, and lacrimation (tear production).
4. Blood vessels: The CPA contains critical blood vessels like the anterior inferior cerebellar artery (AICA), which supplies blood to various parts of the brainstem, cerebellum, and cranial nerves.
5. Meninges: These are protective membranes surrounding the brain and spinal cord. In the CPA, the meninges include the dura mater, arachnoid mater, and pia mater.
Disorders that can affect the structures in the cerebellopontine angle include acoustic neuromas (vestibular schwannomas), meningiomas, epidermoids, and arteriovenous malformations. These conditions may cause symptoms such as hearing loss, tinnitus (ringing in the ears), vertigo (dizziness), facial weakness or numbness, difficulty swallowing, and imbalance.
Brain neoplasms, also known as brain tumors, are abnormal growths of cells within the brain. These growths can be benign (non-cancerous) or malignant (cancerous). Benign brain tumors typically grow slowly and do not spread to other parts of the body. However, they can still cause serious problems if they press on sensitive areas of the brain. Malignant brain tumors, on the other hand, are cancerous and can grow quickly, invading surrounding brain tissue and spreading to other parts of the brain or spinal cord.
Brain neoplasms can arise from various types of cells within the brain, including glial cells (which provide support and insulation for nerve cells), neurons (nerve cells that transmit signals in the brain), and meninges (the membranes that cover the brain and spinal cord). They can also result from the spread of cancer cells from other parts of the body, known as metastatic brain tumors.
Symptoms of brain neoplasms may vary depending on their size, location, and growth rate. Common symptoms include headaches, seizures, weakness or paralysis in the limbs, difficulty with balance and coordination, changes in speech or vision, confusion, memory loss, and changes in behavior or personality.
Treatment for brain neoplasms depends on several factors, including the type, size, location, and grade of the tumor, as well as the patient's age and overall health. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.
Dura Mater is the thickest and outermost of the three membranes (meninges) that cover the brain and spinal cord. It provides protection and support to these delicate structures. The other two layers are called the Arachnoid Mater and the Pia Mater, which are thinner and more delicate than the Dura Mater. Together, these three layers form a protective barrier around the central nervous system.
Neurofibromatosis 2 (NF2) is a genetic disorder characterized by the development of non-cancerous tumors in the nervous system. It is caused by mutations in the NF2 gene, which provides instructions for making a protein called merlin or schwannomin. This protein helps regulate cell growth and plays a role in suppressing tumor formation.
In NF2, the lack of functional merlin protein leads to an increased risk of developing tumors on the nerves related to hearing and balance (vestibular schwannomas or acoustic neuromas), on the spine (schwannomas), and on the brain (meningiomas). These tumors can cause various symptoms, such as hearing loss, ringing in the ears, balance problems, numbness or weakness in the limbs, and visual changes.
NF2 is an autosomal dominant disorder, meaning that a person has a 50% chance of inheriting the mutated gene from an affected parent and developing the condition. However, about half of all NF2 cases result from new mutations in the NF2 gene, with no family history of the disorder.
Medical Definition:
Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.
An acoustic neuroma, also known as vestibular schwannoma, is not actually a neuroma but rather a benign (noncancerous) tumor that develops on the vestibular nerve. This nerve is one of the two nerves that transmit sound and balance information from the inner ear to the brain. The tumor arises from an overproduction of Schwann cells, which normally provide a protective covering for the nerve fibers. As the tumor grows, it can press against the hearing and balance nerves, causing symptoms such as hearing loss, ringing in the ear (tinnitus), unsteadiness, and disequilibrium. In some cases, acoustic neuromas can become quite large and cause additional symptoms by pressing on nearby cranial nerves. Treatment options include observation, radiation therapy, or surgical removal of the tumor.
Optic nerve neoplasms refer to abnormal growths or tumors that develop within or near the optic nerve. These tumors can be benign (non-cancerous) or malignant (cancerous).
Benign optic nerve neoplasms include optic nerve meningiomas and schwannomas, which originate from the sheaths surrounding the optic nerve. They usually grow slowly and may not cause significant vision loss, but they can lead to compression of the optic nerve, resulting in visual field defects or optic disc swelling (papilledema).
Malignant optic nerve neoplasms are rare but more aggressive. The most common type is optic nerve glioma, which arises from the glial cells within the optic nerve. These tumors can quickly damage the optic nerve and cause severe vision loss.
It's important to note that any optic nerve neoplasm requires prompt medical evaluation and treatment, as they can potentially lead to significant visual impairment or even blindness if left untreated.
Hemangiopericytoma is a rare type of soft tissue sarcoma, which is a cancer that develops from the cells that surround blood vessels. It specifically arises from the pericytes, which are cells that help regulate blood flow in capillaries. Hemangiopericytomas typically form in the membranes surrounding the brain and spinal cord (meninges), but they can also occur in other parts of the body such as the lungs, abdomen, or extremities.
These tumors usually grow slowly, but they can become aggressive and spread to other parts of the body (metastasize). Symptoms depend on the location of the tumor, but may include headaches, seizures, weakness, or numbness in the arms or legs. Diagnosis typically involves imaging tests like MRI or CT scans, followed by a biopsy to confirm the presence of cancer cells. Treatment usually consists of surgical removal of the tumor, often accompanied by radiation therapy and/or chemotherapy to help prevent recurrence or spread of the disease.
Neurosurgical procedures are operations that are performed on the brain, spinal cord, and peripheral nerves. These procedures are typically carried out by neurosurgeons, who are medical doctors with specialized training in the diagnosis and treatment of disorders of the nervous system. Neurosurgical procedures can be used to treat a wide range of conditions, including traumatic injuries, tumors, aneurysms, vascular malformations, infections, degenerative diseases, and congenital abnormalities.
Some common types of neurosurgical procedures include:
* Craniotomy: A procedure in which a bone flap is temporarily removed from the skull to gain access to the brain. This type of procedure may be performed to remove a tumor, repair a blood vessel, or relieve pressure on the brain.
* Spinal fusion: A procedure in which two or more vertebrae in the spine are fused together using bone grafts and metal hardware. This is often done to stabilize the spine and alleviate pain caused by degenerative conditions or spinal deformities.
* Microvascular decompression: A procedure in which a blood vessel that is causing pressure on a nerve is repositioned or removed. This type of procedure is often used to treat trigeminal neuralgia, a condition that causes severe facial pain.
* Deep brain stimulation: A procedure in which electrodes are implanted in specific areas of the brain and connected to a battery-operated device called a neurostimulator. The neurostimulator sends electrical impulses to the brain to help alleviate symptoms of movement disorders such as Parkinson's disease or dystonia.
* Stereotactic radiosurgery: A non-invasive procedure that uses focused beams of radiation to treat tumors, vascular malformations, and other abnormalities in the brain or spine. This type of procedure is often used for patients who are not good candidates for traditional surgery due to age, health status, or location of the lesion.
Neurosurgical procedures can be complex and require a high degree of skill and expertise. Patients considering neurosurgical treatment should consult with a qualified neurosurgeon to discuss their options and determine the best course of action for their individual situation.
Ear neoplasms refer to abnormal growths or tumors that occur in the ear. These growths can be benign (non-cancerous) or malignant (cancerous) and can affect any part of the ear, including the outer ear, middle ear, inner ear, and the ear canal.
Benign ear neoplasms are typically slow-growing and do not spread to other parts of the body. Examples include exostoses, osteomas, and ceruminous adenomas. These types of growths are usually removed surgically for cosmetic reasons or if they cause discomfort or hearing problems.
Malignant ear neoplasms, on the other hand, can be aggressive and may spread to other parts of the body. Examples include squamous cell carcinoma, basal cell carcinoma, and adenoid cystic carcinoma. These types of tumors often require more extensive treatment, such as surgery, radiation therapy, and chemotherapy.
It is important to note that any new growth or change in the ear should be evaluated by a healthcare professional to determine the nature of the growth and develop an appropriate treatment plan.
Neurofibromatosis 2 (NF2) is a genetic disorder characterized by the development of non-cancerous tumors in the nervous system, particularly on the nerves related to hearing and balance. It's also known as central neurofibromatosis or bilateral acoustic neuroma syndrome.
The primary feature of NF2 is the growth of schwannomas, which are tumors that develop from the cells surrounding nerve fibers. These typically grow on the vestibular nerve, leading to hearing loss, ringing in the ears (tinnitus), and balance problems. Bilateral acoustic neuromas (schwannomas affecting both vestibular nerves) are a hallmark of this condition.
Other common features include:
1. Meningiomas: These are tumors that grow in the meninges, the protective layers surrounding the brain and spinal cord.
2. Ependymomas: These are tumors that develop from the ependymal cells lining the ventricles (fluid-filled spaces) in the brain or the spinal cord canal.
3. Neurofibromas: Unlike in Neurofibromatosis type 1, these are less common and typically don't become cancerous.
4. Skin changes: While not as prevalent as in NF1, some people with NF2 may have skin freckles, café-au-lait spots, or skin tumors.
5. Eye problems: Some individuals may experience cataracts, retinal abnormalities, or optic nerve tumors (optic gliomas).
6. Other potential symptoms: Headaches, facial weakness or numbness, and difficulty swallowing or speaking.
NF2 is an autosomal dominant disorder, meaning that a person has a 50% chance of inheriting the condition if one of their parents has it. However, about half of all NF2 cases result from spontaneous genetic mutations with no family history of the disorder.
A craniotomy is a surgical procedure where a bone flap is temporarily removed from the skull to access the brain. This procedure is typically performed to treat various neurological conditions, such as brain tumors, aneurysms, arteriovenous malformations, or traumatic brain injuries. After the underlying brain condition is addressed, the bone flap is usually replaced and secured back in place with plates and screws. The purpose of a craniotomy is to provide access to the brain for diagnostic or therapeutic interventions while minimizing potential damage to surrounding tissues.
Cerebral ventricle neoplasms refer to tumors that develop within the cerebral ventricles, which are fluid-filled spaces in the brain. These tumors can arise from various types of cells within the ventricular system, including the ependymal cells that line the ventricles, choroid plexus cells that produce cerebrospinal fluid, or other surrounding tissues.
Cerebral ventricle neoplasms can cause a variety of symptoms depending on their size and location, such as headaches, nausea, vomiting, vision changes, imbalance, weakness, or difficulty with mental tasks. The treatment options for these tumors may include surgical resection, radiation therapy, and chemotherapy, depending on the type and extent of the tumor. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.
A neurilemmoma, also known as schwannoma or peripheral nerve sheath tumor, is a benign, slow-growing tumor that arises from the Schwann cells, which produce the myelin sheath that surrounds and insulates peripheral nerves. These tumors can occur anywhere along the course of a peripheral nerve, but they most commonly affect the acoustic nerve (vestibulocochlear nerve), leading to a type of tumor called vestibular schwannoma or acoustic neuroma. Neurilemmomas are typically encapsulated and do not invade the surrounding tissue, although larger ones may cause pressure-related symptoms due to compression of nearby structures. Rarely, these tumors can undergo malignant transformation, leading to a condition called malignant peripheral nerve sheath tumor or neurofibrosarcoma.
X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.
The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.
CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.
In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.
CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.
In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.
The meninges are the protective membranes that cover the brain and spinal cord. They consist of three layers: the dura mater (the outermost, toughest layer), the arachnoid mater (middle layer), and the pia mater (the innermost, delicate layer). These membranes provide protection and support to the central nervous system, and contain blood vessels that supply nutrients and remove waste products. Inflammation or infection of the meninges is called meningitis, which can be a serious medical condition requiring prompt treatment.
The foramen magnum is the largest opening in the human skull, located at the base of the skull, through which the spinal cord connects to the brain. It is a crucial structure for the transmission of nerve impulses between the brain and the rest of the body. The foramen magnum also provides passage for blood vessels that supply the brainstem and upper spinal cord.
Human chromosome pair 22 consists of two rod-shaped structures present in the nucleus of each cell in the human body. Each chromosome is made up of DNA tightly coiled around histone proteins, forming a complex structure called a chromatin.
Chromosome pair 22 is one of the 22 autosomal pairs of human chromosomes, meaning they are not sex chromosomes (X or Y). Chromosome 22 is the second smallest human chromosome, with each arm of the chromosome designated as p and q. The short arm is labeled "p," and the long arm is labeled "q."
Chromosome 22 contains several genes that are associated with various genetic disorders, including DiGeorge syndrome, velocardiofacial syndrome, and cat-eye syndrome, which result from deletions or duplications of specific regions on the chromosome. Additionally, chromosome 22 is the location of the NRXN1 gene, which has been associated with an increased risk for autism spectrum disorder (ASD) and schizophrenia when deleted or disrupted.
Understanding the genetic makeup of human chromosome pair 22 can provide valuable insights into human genetics, evolution, and disease susceptibility, as well as inform medical diagnoses, treatments, and research.
Neurofibromin 2 is not a medical term itself, but Neurofibromin 1 and Neurofibromin 2 are related to a genetic disorder called Neurofibromatosis. Neurofibromin 1 is the correct term, which is a protein encoded by the NF1 gene in humans.
Neurofibromin 1 is a tumor suppressor protein that plays a crucial role in regulating cell growth and differentiation. Mutations in the NF1 gene can lead to Neurofibromatosis type 1 (NF1), a genetic disorder characterized by the development of benign tumors on the nerves, skin, and other parts of the body.
Neurofibromin 2, on the other hand, is not a recognized term in medical literature. It is possible that there is some confusion with Neurofibromatosis type 2 (NF2), which is a separate genetic disorder caused by mutations in the NF2 gene. The NF2 gene encodes a protein called Merlin, which also functions as a tumor suppressor and helps regulate cell growth and division.
Therefore, it is essential to clarify whether you are asking about Neurofibromin 1 or Neurofibromatosis type 2 when using the term "Neurofibromin 2."
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Desmoplastic fibroma is a very rare benign (non-cancerous) tumor of the connective tissue. It typically develops in the bones, but can also occur in soft tissues. The tumor is characterized by the overgrowth of collagen-producing cells (fibroblasts), leading to the formation of a firm, fibrous mass. Desmoplastic fibromas are slow-growing and typically do not spread to other parts of the body (metastasize). However, they can cause significant damage to the affected bone or tissue as they grow, potentially leading to fractures or deformities. Treatment usually involves surgical removal of the tumor.
Hemangioendothelioma is a rare type of vascular tumor, which means it arises from the endothelial cells that line the blood vessels. It can occur in various parts of the body, but it most commonly involves the soft tissues and bones. Hemangioendotheliomas are often classified as borderline malignant tumors because they can behave either indolently (like a benign tumor) or aggressively (like a malignant tumor), depending on their specific type and location.
There are several subtypes of hemangioendothelioma, including:
1. Epithelioid hemangioendothelioma: This subtype typically affects young adults and can involve various organs, such as the liver, lungs, or soft tissues. It tends to have a more indolent course but can metastasize in some cases.
2. Kaposiform hemangioendothelioma: This is an aggressive subtype that usually occurs in infants and children. It often involves the skin and soft tissues, causing local invasion and consumptive coagulopathy (Kasabach-Merritt phenomenon).
3. Retiform hemangioendothelioma: A rare and low-grade malignant tumor that typically affects the skin and subcutaneous tissue of adults. It has a favorable prognosis with a low risk of metastasis.
4. Papillary intralymphatic angioendothelioma (PILA): This is a rare, slow-growing tumor that usually occurs in the head and neck region of children and young adults. It has an excellent prognosis with no reported cases of metastasis or recurrence after complete surgical resection.
Treatment for hemangioendotheliomas typically involves surgical excision when possible. Other treatment options, such as radiation therapy, chemotherapy, or targeted therapies, may be considered depending on the tumor's location, size, and behavior. Regular follow-up is essential to monitor for potential recurrence or metastasis.
Radiosurgery is a non-invasive surgical procedure that uses precisely focused beams of radiation to treat various medical conditions, primarily in the field of neurosurgery and oncology. It allows for the destruction of targeted tissue while minimizing damage to surrounding healthy structures. Unlike traditional surgery, radiosurgery does not require any incisions, as it delivers radiation through the skin to reach the intended target.
The term "stereotactic" is often associated with radiosurgery, which refers to the use of a three-dimensional coordinate system to precisely locate and target the affected area. This technique enables high doses of radiation to be delivered accurately and efficiently, maximizing therapeutic effectiveness while minimizing side effects.
Radiosurgery can be used to treat various conditions such as brain tumors (both malignant and benign), arteriovenous malformations (AVMs), trigeminal neuralgia, acoustic neuromas, pituitary adenomas, and spinal cord tumors. Common radiosurgery platforms include the Gamma Knife, CyberKnife, and linear accelerator-based systems like Novalis Tx or TrueBeam.
It is essential to note that although it is called "surgery," radiosurgery does not involve any physical incisions or removal of tissue. Instead, it relies on the destructive effects of high-dose radiation to ablate or damage targeted cells over time, leading to their eventual death and resolution of symptoms or tumor control.
Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.
In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.
For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.
Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.
Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.
Trigeminal neuralgia is a chronic pain condition that affects the trigeminal nerve, which is one of the largest nerves in the head. It carries sensations from the face to the brain.
Medically, trigeminal neuralgia is defined as a neuropathic disorder characterized by episodes of intense, stabbing, electric shock-like pain in the areas of the face supplied by the trigeminal nerve (the ophthalmic, maxillary, and mandibular divisions). The pain can be triggered by simple activities such as talking, eating, brushing teeth, or even touching the face lightly.
The condition is more common in women over 50, but it can occur at any age and in either gender. While the exact cause of trigeminal neuralgia is not always known, it can sometimes be related to pressure on the trigeminal nerve from a nearby blood vessel or other causes such as multiple sclerosis. Treatment typically involves medications, surgery, or a combination of both.
The Sella Turcica, also known as the Turkish saddle, is a depression or fossa in the sphenoid bone located at the base of the skull. It forms a housing for the pituitary gland, which is a small endocrine gland often referred to as the "master gland" because it controls other glands and makes several essential hormones. The Sella Turcica has a saddle-like shape, with its anterior and posterior clinoids forming the front and back of the saddle, respectively. This region is of significant interest in neuroimaging and clinical settings, as various conditions such as pituitary tumors or other abnormalities may affect the size, shape, and integrity of the Sella Turcica.
Meningioma
Malignant meningioma
Cutaneous meningioma
Sphenoid wing meningioma
Optic nerve sheath meningioma
List of OMIM disorder codes
Brain tumor
Robert Schumann
Steinheim skull
Melanocytoma
TBX3
Hemangiopericytoma
Inferior hypophysial artery
Pia mater
Foramen spinosum
Gabriel Zada
Foramen lacerum
Posterior ethmoidal nerve
Differential diagnoses of depression
Dural tail sign
Trabectedin
Side effects of cyproterone acetate
AP1B1
Vladimir Cerrón
Mary Tyler Moore filmography and awards
Monostotic fibrous dysplasia
Mary Tyler Moore
PDGFB
Leonard Wood
William Couldwell
Meningioma - Wikipedia
Meningioma in Cats
Optic Nerve Sheath Meningioma: Background, Pathophysiology, Epidemiology
What to Expect After Benign Meningioma Surgery
Updates in Glioma and Meningioma… | College of American Pathologists
Leksell Top 25 - Meningioma Journals
Spinal Meningioma Tumor Symptoms and Surgical Treatment | UPMC
Meningioma at 20x Magnification | Nikon's MicroscopyU
Optic Nerve Sheath Meningioma Follow-up: Further Outpatient Care, Complications, Prognosis
CNV-Adjusted Analysis Points to Prognostically Informative Meningioma Methylation Groups | GenomeWeb
Meningiomas - Classifications, Risk Factors, Diagnosis and Treatment
Meningioma pathophysiology - wikidoc
Microcystic Variant of an Intraosseous Meningioma in the Frontal Area: A Case Report
Evaluation of Magnetic Resonance Imaging for Microsurgical Efficacy and Relapse of Rolandic Meningioma
Visualisation application leads to meningioma discovery | Scientific Computing World
meningioma | SD Entertainer Magazine
Angioblastic meningioma with hepatic metastasis | Journal of Neurology, Neurosurgery & Psychiatry
Use of high dose cyproterone acetate and risk of intracranial meningioma in women: cohort study | The BMJ
Meningioma: Practice Essentials, Background, Pathophysiology
Meningioma Market Size, Trends and Forecast 2023-2033
Earning Doctorate After Studying Clinical Aspect of Meningioma - Universitas Gadjah Mada
Crush Cytology of a Primary Intraspinal Rhabdoid Papillary Meningioma: A Case Report | Acta Cytologica | Karger Publishers
Living well with a meningioma - Brainstrust, brain tumour charity
Meningioma Stem Cells - Brain Science Foundation
Convexity meningioma | Radiology Case | Radiopaedia.org
Kinome and phosphoproteome of high-grade meningiomas reveal AKAP12 as a central regulator of aggressiveness and its possible...
Computed Tomography Use in Canine Meningioma: Case Report - WSAVA2009 - VIN
Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma
Observation or Radiation Therapy in Treating Patients with Newly Diagnosed Grade II Meningioma that has been Completely Removed...
Neuromas and meningiomas: evaluation of early enhancement with dynamic MR imaging. | American Journal of Neuroradiology
Recurrence9
- Studies indicate that up to 20% of people have meningioma recurrence within 10 years. (healthline.com)
- Higher-grade meningiomas have a higher recurrence rate, ranging from 50%-94% for grade 3, while grade 1 and grade 2 meningiomas have lower rates of 7%-25% and 29%-52%, respectively. (healthline.com)
- Atypical meningiomas have a higher likelihood of recurrence than benign meningiomas (WHO grade I). (aans.org)
- NDRG2 (N-Myc downstream-regulated gene 2): Down regulation of this gene expression at the mRNA level is associated with the malignant progression and predisposition to recurrence of meningiomas. (wikidoc.org)
- Dr Bárbara Meléndez and her colleagues in the Unidad de Investigación de Patología Molecular (Molecular Pathology Research Unit) at Hospital Virgen de la Salud in Toledo, Spain, are using Qlucore Omics Explorer to investigate how generally benign meningiomas can start to exhibit the sort of histology and recurrence usually associated with more aggressive tumours. (scientific-computing.com)
- Dr. Johnson's work offers the promise of specifically studying the small proportion of meningioma cells that are responsible for meningioma growth and recurrence. (brainsciencefoundation.org)
- The recurrence of intracranial meningiomas after surgical treatment. (scienceopen.com)
- 18F-FDG PET in the assessment of tumor grade and prediction of tumor recurrence in intracranial meningioma. (medscape.com)
- Only 1 patient harboring a left cavernous sinus meningioma had tumor recurrence and underwent repeat resection. (medscape.com)
Diagnosis of meningioma3
- The diagnosis of meningioma involves a combination of clinical evaluation, imaging studies, and pathological examination. (imarcgroup.com)
- Pathologic analysis confirmed the diagnosis of meningioma in all cases. (ajnr.org)
- BACKGROUND: The concurrent diagnosis of meningioma with increased intracranial pressure has not been reported previously in a patient who meets diagnostic criteria for multiple chemical sensitivities (MCS). (cdc.gov)
Resection15
- One study found that 5.7% of people undergoing microsurgical resection for intracranial meningiomas developed venous thromboembolism . (healthline.com)
- While surgical resection can lead to seizure freedom in 60%-90% of people with meningioma, approximately 12%-19% still experience seizures after surgery. (healthline.com)
- Resection can be undertaken for posterior fossa meningiomas, but residual or recurrent tumor is frequent. (thejns.org)
- 65 y) to younger patients, Black et al evaluated 114 patients undergoing meningioma resection divided into 2 groups, as follows: 57 patients aged 65-87 years and a control group of 57 patients aged 25-64 years matched by the American Society of Anesthesiology (ASA) status and tumor site. (medscape.com)
- Surgical resection and postoperative radiotherapy and chemotherapy are the main methods for the treatment of meningioma, but surgical resection can only control the tumor locally. (hindawi.com)
- Main outcome measure Surgery (resection or decompression) or radiotherapy for one or more intracranial meningiomas. (bmj.com)
- In general, the ideal treatment of a benign meningioma is surgical resection if possible. (medscape.com)
- Over 40% of atypical meningiomas will reoccur after gross resection. (nature.com)
- Preoperative embolization of meningiomas can reduce surgical blood loss, shorten operation length, reduce the risk of damage to surrounding structures, and increase the likelihood of complete tumor resection. (ajnr.org)
- Preoperative embolization for intracranial meningiomas offers potential advantages for safer and more effective subsequent resection. (cns.org)
- Retrospective review of patients undergoing intracranial meningioma resection at UVA Hospital 01/2009-12/2012. (cns.org)
- The aim of surgery for skull base meningiomas is maximal resection with minimal damage to the involved cranial nerves and cerebral vessels. (uni-marburg.de)
- Compared to non-skull base meningiomas, these lesions show a reduced rate of gross total resection (GTR). (uni-marburg.de)
- Skull-base location represents 20-30% of all intracranial meningiomas, being considered as a challenging region in terms of clinical symptoms, surgical accessibility, and complete resection achievement. (cns.org)
- A retrospective clinical records review of patients who underwent first-time surgical resection of meningioma (WHO grade 1) at Johns Hopkins Hospital between 2003 and 2015. (cns.org)
Atypical11
- Coke CC, Corn BW, Werner-Wasik M, Xie Y, Curran WJ Jr. Atypical and malignant meningiomas: an outcome report of seventeen cases. (medscape.com)
- Long-term survival is possible for patients with atypical and malignant meningiomas treated with surgery and postoperative radiation. (medscape.com)
- The series by Milosevic et al included the records of 59 patients who were treated at the Princess Margaret Hospital from 1966-1990 with histologically confirmed intracranial atypical or malignant meningiomas. (medscape.com)
- Young age, modern imaging and treatment planning techniques, and postoperative radiation dose of at least 50 Gy contribute to improved outcome in patients with atypical or malignant meningiomas. (medscape.com)
- Atypical meningiomas (WHO grade II, which account for 18% of meningioma cases) exhibit increased tissue and cell abnormalities. (aans.org)
- Malignant meningiomas (WHO grade III) show increased cellular abnormalities and grow at a faster rate than benign and atypical meningiomas. (aans.org)
- The majority of meningiomas are benign (90%), about 6% are atypical, and 2% are malignant . (wikidoc.org)
- Rhabdoid papillary meningiomas, encountered less often, should be distinguished from metastatic tumors of rhabdoid or papillary configuration, astrocytomas, ependymomas and atypical teratoid/rhabdoid tumor. (karger.com)
- In the present work, we introduce a combination of mass spectrometry-based phosphoproteomics and peptide array kinomics to profile atypical and anaplastic (high-grade) meningiomas. (nature.com)
- Although most meningiomas are benign, 15-35% represents atypical or anaplastic forms 3 . (nature.com)
- In contrast, meningiomas with mutant NF2 and/or chromosome 22 loss were more likely to be atypical, showing genomic instability, and localizing to the cerebral and cerebellar hemispheres. (scienceopen.com)
Malignant meningiomas3
- The less common malignant meningiomas are faster growing and may grow in the surrounding tissue. (upmc.com)
- Malignant meningiomas are surgically removed whenever possible, while benign meningiomas are removed if they are large and/or causing problems. (upmc.com)
- Long-term experience with World Health Organization grade III (malignant) meningiomas at a single institution. (medscape.com)
Neurosurgery4
- According to the records of the Department of Neurosurgery in Bielsko-Biała, 133 patients diagnosed with an intracranial meningioma confirmed by a histopathological test were operated in the last 10 years (2004-2014). (hindawi.com)
- According to our own records, out of 14 cases of the bone tumours of the calvaria operated in the period from January 2004 to February 2014 at our Department of Neurosurgery, meningiomas constituted 21% of the cases. (hindawi.com)
- Consequently, MR imaging technology has been widely applied in the evaluation of postoperative tumor relapse in patients who receive neurosurgery operations such as meningioma. (hindawi.com)
- In neurosurgery field, there have been many treatments of meningioma tumor which has progesterone receptor and it is often associated with hyperostosis in calvaria bone as a proof of progesterone receptor role in making the bone matrix, thus causing hyperostosis in the calvaria bone. (ugm.ac.id)
Symptoms17
- Symptoms of meningiomas are caused by pressure from the growing tumor on the surrounding tissue. (upmc.com)
- If a meningioma is small and does not cause symptoms, doctors may observe it over time rather than treating it immediately. (upmc.com)
- The symptoms of meningioma can be flared by water retention, engorgement of blood vessels , and the presence of sex hormone receptors on tumor cells. (wikidoc.org)
- Meningiomas produce their symptoms by several mechanisms. (medscape.com)
- A systematic review of the literature regarding the clinical behavior of small, untreated meningiomas suggests that most meningiomas 2.5 cm or less in diameter do not proceed to cause symptoms in the 5 years following their discovery. (medscape.com)
- Videos had a significantly higher DISCERN scores if they included information about the symptoms of meningioma, risk factors during treatment, prognosis or included animations and diagrams. (physiciansweekly.com)
- Symptoms of Meningiomas by. (msdmanuals.com)
- The meningioma may not be your issue, given other symptoms you're having. (mayoclinic.org)
- Although most meningiomas are slow growing, they can still cause symptoms by exerting pressure on the brain and spinal cord. (targetingcancer.com.au)
- What are the symptoms of a Meningioma? (targetingcancer.com.au)
- Small meningiomas do not usually cause symptoms and are found incidentally when a scan of the brain or spine is performed for an unrelated reason. (targetingcancer.com.au)
- Large meningiomas can exert pressure on the normal brain or spinal cord which can result in symptoms. (targetingcancer.com.au)
- Meningiomas may cause seizures or focal neurological symptoms such as visual changes, loss of hearing or smell, or limb weakness. (targetingcancer.com.au)
- The recommended treatment for a meningioma will depend on the location and grade, whether it is causing symptoms and the age and general health of the patient. (targetingcancer.com.au)
- For small low grade meningiomas that are not causing symptoms close observation with repeat imaging may be recommended. (targetingcancer.com.au)
- If the meningioma increases in size quickly or starts causing symptoms, treatment would then be recommended. (targetingcancer.com.au)
- Removal of the meningioma had little effect on the patient's symptoms. (cdc.gov)
Anaplastic3
- In particular most WHO grade I meningiomas are benign, while grade III (anaplastic) are aggressive. (scientific-computing.com)
- AKAP12 knockdown in benign meningioma cells SF4433 increases proliferation, cell cycle, migration, invasion, and confers an anaplastic profile. (nature.com)
- Anaplastic meningiomas lead to fatal outcomes despite surgery, radiation, and experimental medications. (nature.com)
Underwent3
- A Swedish registry-based study analyzed 2,324 people who underwent surgery for intracranial meningioma, with 14.1% being asymptomatic before surgery. (healthline.com)
- The following study presents the case of a microcystic meningioma found in a 59-year-old woman who underwent a successful surgical treatment. (hindawi.com)
- From February 2008 to January 2010, 5 patients with untreated intracranial meningiomas fed mainly by OPH branches underwent preoperative embolization with Onyx-18 at our institution. (ajnr.org)
Skull14
- Skull base meningiomas greater than 8 cm 3 in volume have been found to have worse outcomes following SRS. (thejns.org)
- In this study, the authors review the SRS outcomes of skull base meningiomas greater than 8 cm 3 in volume, which corresponds to a lesion with an approximate diameter of 2.5 cm. (thejns.org)
- The authors reviewed the data in a prospectively compiled database documenting the outcomes of 469 patients with skull base meningiomas treated with single-session Gamma Knife radiosurgery (GKRS). (thejns.org)
- Some meningiomas are found along the dural lining in the venous sinuses of the brain and skull base - locations where arachnoid cap cells are most abundant. (aans.org)
- Meningiomas are commonly found in the base of the skull and perivenous sinuses due to the abundance of arachnoid cap cells in these sites. (wikidoc.org)
- Meningiomas located in the anterior skull base and middle skull base, particularly the medial third of the middle skull base, involving the spheno-orbital region, appeared to be specific to cyproterone acetate. (bmj.com)
- Meningiomas commonly are found at the surface of the brain, either over the convexity or at the skull base. (medscape.com)
- 1 - 11 Embolization becomes especially important when meningiomas are located at the skull base, because of the difficulties of bleeding management in this region. (ajnr.org)
- 2 , 11 , 12 The blood supply of meningiomas usually arises from branches of the external carotid artery, except in cases of anterior and middle skull base tumors. (ajnr.org)
- Clinical Features and Neuroimaging Volumetrics in a Cohort of Patients with Skull Base Meningiomas: Retraction vs. Non-retraction? (cns.org)
- Meningiomas, which are usually benign, can develop wherever there is dura, most commonly over the convexities near the venous sinuses, along the base of the skull, and in the posterior fossa and rarely within ventricles. (msdmanuals.com)
- These non-NF2 meningiomas were clinically distinctive-nearly always benign, with chromosomal stability, and originating from the medial skull base. (scienceopen.com)
- Abdel Kerim A, Bonneville F, Jean B, Cornu P, LeJean L, Chiras J. Balloon-assisted embolization of skull base meningioma with liquid embolic agent. (medscape.com)
- It occurs in a wide variety of anterior skull base meningiomas and it can be bilateral. (medscape.com)
Surgical5
- A study of 69 people with meningioma found that larger tumors showed higher rates of headache improvement after surgery, providing promising results for the surgical treatment. (healthline.com)
- They attributed the lower morbidity and mortality rates after meningioma surgery in elderly patients to better patient selection and surgical techniques and to better preoperative and postoperative care by health care providers. (medscape.com)
- According to some explorations, the relapse rate of patients with meningioma after surgical treatment is over 20% [ 5 ]. (hindawi.com)
- In the surgical treatment of patients with Rolandic meningioma, the functional area cortex and central sulcus vein need to be protected. (hindawi.com)
- Majchrzak K, Tymowski M. Surgical treatment of the tentorial and falco-tentorial junction meningiomas. (medscape.com)
Histologically2
- citation needed] Histologically, meningioma cells are relatively uniform, with a tendency to encircle one another, forming whorls and psammoma bodies (laminated calcific concretions). (wikipedia.org)
- Have a newly diagnosed unifocal intracranial meningioma, gross totally resected, and histologically confirmed as WHO grade II based upon pathology findings at the enrolling institution. (rush.edu)
Symptomatic4
- Symptomatic meningiomas require some form of treatment. (upmc.com)
- The annual incidence of symptomatic meningiomas is approximately 2 cases per 100,000 individuals. (medscape.com)
- This is strengthened by several case reports which stated that meningioma tumor gets bigger quickly and becomes symptomatic during hormonal fluctuation, particularly during pregnancy and luteal phase of menstruation cycle. (ugm.ac.id)
- Symptomatic or enlarging meningiomas should be excised if possible. (msdmanuals.com)
High grade meningiomas4
- Meléndez explained: 'World Health Organisation (WHO) low grade meningiomas (grade I) and WHO high grade meningiomas (grades II and III) are different in their histopathlogy and prognosis. (scientific-computing.com)
- Differentially regulated pathways were characteristic of high-grade meningiomas. (nature.com)
- High-grade meningiomas (II and III) do not respond well to surgery and lead to decreased survival. (nature.com)
- Understanding pathways of oncogenesis that drive high-grade meningiomas is important to improve current diagnosis and treatment. (nature.com)
Posterior fossa meningioma1
- At 7 medical centers participating in the North American Gamma Knife Consortium, 675 patients undergoing SRS for a posterior fossa meningioma were identified, and clinical and radiological data were obtained for these cases. (thejns.org)
Clinical10
- Posterior fossa meningiomas represent a common yet challenging clinical entity. (thejns.org)
- Integrating genetic, epigenetic, transcriptomic, biochemical, proteomic, and single-cell approaches, we find meningiomas are composed of three DNA methylation groups with distinct clinical outcomes and biological drivers. (genomeweb.com)
- U]sing bioinformatic pipelines that account for the impact of CNVs on beta methylation detection, we identify three robust DNA methylation groups of meningiomas with distinct clinical outcomes, biological drivers, and therapeutic vulnerabilities," Raleigh wrote, adding that "ours is the first meningioma epigenetic study to validate all the bioinformatic groups we report using mechanistic and functional approaches across meningioma cells, organoids, xenografts, and patients. (genomeweb.com)
- In contrast to meningiomas arising in neurofibromatosis type 2 patients missing an NF2 gene coding for the Merlin tumor suppressor protein, the researchers found that more than one-third of the meningiomas fell into a Merlin-intact group with the most favorable clinical outcomes and vulnerability to cytotoxic therapy. (genomeweb.com)
- These findings underscore the importance of DNA methylation profiling for meningioma patients, which (we anticipate) will ultimately allow for selection or enrollment of clinical trials of cell cycle inhibitors or other molecular therapies," Raleigh explained. (genomeweb.com)
- Objective To assess the risk of meningioma associated with use of high dose cyproterone acetate, a progestogen indicated for clinical hyperandrogenism. (bmj.com)
- Al-Habib A, Lach B, Al Khani A: Intracerebral rhabdoid and papillary meningioma with leptomeningeal spread and rapid clinical progression. (karger.com)
- Ibebuike K, Ouma J, Gopal R. Meningiomas among intracranial neoplasms in Johannesburg, South Africa: prevalence, clinical observations and review of the literature. (medscape.com)
- Papillary meningioma: clinical and histopathological observations. (medscape.com)
- Meningioma as a rare cause of underlying clinical stroke. (bvsalud.org)
Glioma and meningioma2
Majority of meningiomas2
- Although the majority of meningiomas are benign , these tumors can grow slowly until they are very large, if left undiscovered, and, in some locations, can be severely disabling and life-threatening. (aans.org)
- The majority of meningiomas are benign . (wikidoc.org)
Frequency of meningiomas2
- The frequency of meningiomas has been the topic of relatively few reports. (medscape.com)
- The frequency of meningiomas in Africa is nearly 30% of all primary intracranial tumors. (medscape.com)
Neurofibromatosis4
- Multiple endocrine neoplasia 1 , cowden syndrome , werner syndrome and neurofibromatosis 2 are some of the conditions that may be associated with meningioma. (wikidoc.org)
- Meningiomas are multiple in 5-40% of cases, particularly when they associated with neurofibromatosis type 2 (NF2). (medscape.com)
- People with certain mutations in the neurofibromatosis gene (NF2) have a very substantial increased risk for meningioma. (scienceopen.com)
- Genetic factors: Patients with genetic disorders such as Neurofibromatosis type 2, Schwannomatosis and Multiple Endocrine Neoplasia type 1 (MEN1) have an increased risk of developing meningiomas. (targetingcancer.com.au)
Rhabdoid9
- Both rhabdoid and papillary meningioma are rare variants of meningioma categorized as WHO grade III. (karger.com)
- Here, we report a rare case of combined rhabdoid papillary meningioma with discussion of its differential intraoperative cytologic diagnoses. (karger.com)
- We also emphasize that the present case is the first case of rhabdoid papillary meningioma with primary manifestation in the spinal cord. (karger.com)
- Kepes JJ, Moral LA, Wilkinson SB, Abdullah A, Llena JF: Rhabdoid transformation of tumor cells in meningiomas: a histologic indication of increased proliferative activity: report of four cases. (karger.com)
- Hojo H, Abe M: Rhabdoid papillary meningioma. (karger.com)
- Wakabayashi K, Suzuki N, Mori F, Kamada M, Hatanaka M: Rhabdoid cystic papillary meningioma with diffuse subarachnoid dissemination. (karger.com)
- Eom KS, Kim DW, Kim TY: Diffuse craniospinal metastases of intraventricular rhabdoid papillary meningioma with glial fibrillary acidic protein expression: a case report. (karger.com)
- Wu YT, Ho JT, Lin YJ, Lin JW: Rhabdoid papillary meningioma: a clinicopathologic case series study. (karger.com)
- Intracerebral cystic rhabdoid meningioma. (medscape.com)
ONSM4
- The term optic nerve sheath meningioma (ONSM) does not indicate a definite site of origin. (medscape.com)
- Secondary ONSM are extensions of intracranial meningioma into the orbit. (medscape.com)
- Secondary ONSMs are much more common than primary ONSMs, but the unqualified term "optic nerve sheath meningioma" ordinarily refers to primary ONSM. (medscape.com)
- Outpatient follow-up care of patients with optic nerve sheath meningioma (ONSM) includes visual acuity testing and field testing, in addition to an imaging study in the form of MRI with gadolinium, preferably every year to check for recurrent disease. (medscape.com)
Subtypes3
- These variations are called meningioma subtypes - the technical term for these cell variations is histological subtypes. (aans.org)
- The research has led to a discovery, as Meléndez explained: 'Expression analyses allowed us to identify that meningiomas can be classified into an aggressive and a non-aggressive group - despite WHO classification criteria establishing three malignancy groups and about 15 histopathological subtypes. (scientific-computing.com)
- Collectively, these findings identify distinct meningioma subtypes, suggesting avenues for targeted therapeutics. (scienceopen.com)
Meninges10
- Meningioma, also known as meningeal tumor, is typically a slow-growing tumor that forms from the meninges, the membranous layers surrounding the brain and spinal cord. (wikipedia.org)
- Meningioma is a benign brain tumor that originates from your meninges, the protective layers surrounding your brain and spinal cord. (healthline.com)
- A meningioma is a tumor that grows in the protective lining of the brain and spinal cord, called the meninges. (upmc.com)
- Meningioma arises from the arachnoid "cap" cells, which are normally involved in the protection of the central nervous system by forming a thick envelope of meninges around the brain and spinal cord . (wikidoc.org)
- Therefore, meningioma in the Rolandic area is more closely attached to meninges or veins. (hindawi.com)
- Meningioma refers to a set of tumors that arise contiguously to the meninges (see the image below). (medscape.com)
- Meningioma is a type of tumor that arises from the meninges, which are the protective membranes that surround the brain and spinal cord. (imarcgroup.com)
- Meningiomas are tumors of the meninges that can compress adjacent brain tissue. (msdmanuals.com)
- Meningiomas are tumors of the meninges that are usually but not always benign. (msdmanuals.com)
- A Meningioma is a common type of brain tumour arising from the tissue lining the brain and spinal cord (meninges). (targetingcancer.com.au)
Treat meningiomas2
- Stereotactic radiosurgery (SRS) has been used to treat meningiomas, and this study evaluates the outcome of this approach for those located in the posterior fossa. (thejns.org)
- UPMC neurosurgeons may also treat meningiomas with stereotactic spine radiosurgery , which is a minimally invasive technique that uses highly focused beams of radiation to target spinal tumors. (upmc.com)
Small meningiomas2
- For asymptomatic small meningiomas, particularly in older adults, monitoring with serial neuroimaging is sufficient. (msdmanuals.com)
- Treatment decision making based on the published natural history and growth rate of small meningiomas. (medscape.com)
Multiple meningiomas4
- Predisposes to multiple meningiomas preferentially in the falx cerebri . (wikidoc.org)
- With multiple meningiomas, there's also the possibility of stereotactic radiosurgery . (thebraintumourcharity.org)
- Multiple meningiomas may develop. (msdmanuals.com)
- Multiple meningiomas in a patient with Rubinstein-Taybi syndrome. (medscape.com)
Histological4
- Some meningiomas may be positive for progesterone receptors on histological examination. (wikidoc.org)
- The characteristics of a meningioma can be determined based on histopathological variables like tumor gradient, histological subtype, proliferative index, and invasiveness of a tumor to the brain . (wikidoc.org)
- Seen in meningiomas undergoing malignant histological progression. (wikidoc.org)
- The histological diagnosis was meningioma. (bmj.com)
Tumors that arise1
- Another rare group of meningiomas consists of tumors that arise from ectopic arachnoid cells within the orbital cavity, either in the muscle cone or in the walls of the orbit. (medscape.com)
Patients21
- In one series of 517 patients with meningiomas at Brigham and Women's Hospital, the female-to-male ratio was 24:1. (medscape.com)
- In one retrospective series at the King Faisal Hospital from 1980-1993 that included a total of 318 patients with meningiomas, only 2.8% of patients were children aged 16 years or younger. (medscape.com)
- Stereotactic radiosurgery affords a high rate of tumor control and neurological preservation for patients with posterior fossa meningiomas. (thejns.org)
- Of these, 36 patients died of meningioma, and 3 patients were alive after further surgery. (medscape.com)
- The data presented here demonstrate a need for DNA methylation profiling to stratify meningioma patients for molecular therapy," co-senior and co-corresponding author David Raleigh, a radiation oncology and neurological surgery researcher at UCSF, and his colleagues wrote. (genomeweb.com)
- He and his coauthors emphasized the need for "careful consideration of meningioma DNA methylation groups in the context of available preclinical data, and WHO grade, when stratifying meningioma patients for new treatments," though they cautioned that the current results suggest that "DNA methylation grouping does not obviate the importance of meningioma grading. (genomeweb.com)
- In this study, magnetic resonance imaging (MRI) was used to evaluate the relapse features of patients with Rolandic meningioma after the microsurgery. (hindawi.com)
- 53 patients with Rolandic meningioma were selected as the research objects, and they were divided into the relapse group ( n = 16) and nonrelapse group ( n = 37) according to whether patients had a relapse during the follow-up period. (hindawi.com)
- To sum up, the microsurgical treatment helped improve the quality of life of patients with Rolandic meningioma, and MR imaging could be used to determine the relapse of Rolandic meningioma after microsurgical treatment. (hindawi.com)
- The relapse rate and disability rate of patients with Rolandic meningioma are much higher than those of patients with convex meningioma [ 6 ]. (hindawi.com)
- In order to investigate the value of MRI in evaluating the efficacy of microsurgical treatment of patients with meningioma, patients with Rolandic meningioma treated by microsurgery were selected as the study subjects. (hindawi.com)
- Therefore, some patients die with meningioma and not from it. (medscape.com)
- We will be looking carefully at the 3-year results, and expect surgery with complete removal alone to control a WHO grade II meningioma in around 70% of patients at that interval. (froedtert.com)
- The impact of inaccurate YouTube videos on patients' understanding of meningioma treatment must be recognized by healthcare professionals. (physiciansweekly.com)
- This randomized phase III trial studies how well radiation therapy works compared with observation in treating patients with newly diagnosed grade II meningioma that has been completely removed by surgery. (rush.edu)
- Meningiomas may take more than 20 years to develop after exposure to ionising radiation, so this risk is thought to be highest for patients exposed to radiation at a young age. (targetingcancer.com.au)
- Methods The authors performed a retrospective analysis of 45 patients with anterior and middle fossa meningiomas with involvement of the optic pathway in whom surgery was performed by the senior author (O.A.M.) during the period from 1993 to 2007. (medscape.com)
- Visual disturbance due to optic nerve compression is the initial presentation for many patients with anterior and middle fossa meningiomas. (medscape.com)
- In this study we review 45 patients with meningiomas extending into the optic canal, and we discuss the pattern of involvement of the canal and implications for method of decompression as well as the outcome. (medscape.com)
- Those who evaluate patients with MCS are reminded that meningiomas and other intracranial mass lesions can affect olfaction, and that patients with MCS can have treatable intracranial abnormalities. (cdc.gov)
- In patients with gliomas and meningiomas, faster exchange was tentatively associated with higher tumor grade. (lu.se)
Asymptomatic1
- However, the true prevalence is likely higher than this because autopsy studies reveal that 2.3% of individuals have undiagnosed asymptomatic meningiomas. (medscape.com)
Intraventricular2
- In rare cases, meningiomas occur in an intraventricular or intraosseous location. (medscape.com)
- Intraventricular chordoid meningioma presenting with Castleman disease due to overproduction of interleukin-6. (medscape.com)
Prognosis1
- This strategy was used to better understand the underlying mechanisms of meningioma malignancy, aid in the development of novel therapies and markers of poor prognosis. (nature.com)
Intracranial tumor2
- Meningiomas are the most common benign intracranial tumor . (aans.org)
- Meningioma is a very common intracranial tumor that originates from arachnoid cells and is only less common than glioma [ 1 ]. (hindawi.com)
Conclusions2
Neoplasms2
- The current trend is to separate unequivocal meningiomas from other less well-defined neoplasms. (medscape.com)
- Meningiomas account for approximately 20% of all primary intracranial neoplasms. (medscape.com)
Optic nerve4
- Meningiomas near your optic nerve or visual pathways can lead to lingering visual disturbances or changes in your vision. (healthline.com)
- These ectopic, extradural meningiomas do not appear to have a connection to the optic nerve sheath or the optic canal and do not appear to originate intracranially. (medscape.com)
- Background/aims To review the long-term results of treatment of optic nerve sheath meningiomas (ONSMs) with conformal radiotherapy. (bmj.com)
- Optic nerve and cavernous sinus meningiomas are uncommon pathologies, and so far there have not been previously reported to occur in the same patient. (bvsalud.org)
Cases per 100,0002
- The incidence of meningiomas increases with age, 2-7 cases per 100,000 in women and 1-5 cases per 100,000 in men. (medscape.com)
- Meningioma is an intracranial benign tumor which is often found with the number of incidents varies depending on the research in each country with the average of 0.61-2.42% cases per 100,000 people. (ugm.ac.id)
Liquid embolic agent1
- This study assesses the safety and efficacy of preoperative embolization of meningiomas fed by the OPH by using Onyx liquid embolic agent. (ajnr.org)
Treatment16
- Stereotactic radiosurgery (SRS) has become a common treatment modality for intracranial meningiomas. (thejns.org)
- UPMC offers several treatment options for meningioma, including minimally invasive surgery and stereotactic radiosurgery, offering benefits such as minimal scarring, fewer side effects, and faster recovery. (upmc.com)
- In addition to this, the rising demand for targeted therapies, such as somatostatin receptor analogs, tyrosine kinase inhibitors, mTOR inhibitors, etc., which aim to disrupt signaling pathways specific to meningiomas, thereby potentially improving treatment outcomes, is also bolstering the market growth. (imarcgroup.com)
- According to the report the United States has the largest patient pool for meningioma and also represents the largest market for its treatment. (imarcgroup.com)
- A better understanding of what makes these cells different from other meningioma cells may help us to find new therapies for the treatment of meningiomas. (brainsciencefoundation.org)
- Quality of YouTube videos on meningioma treatment using the DISCERN instrument. (physiciansweekly.com)
- To assess the quality of YouTube videos on meningioma treatment. (physiciansweekly.com)
- The information content on meningioma treatment in YouTube videos was generally poor. (physiciansweekly.com)
- Your medical team will consider a range of factors about your meningioma when deciding the most appropriate treatment. (thebraintumourcharity.org)
- However, treatment for more than one meningioma may be different as the tumours may be of different grades and have different growth rates. (thebraintumourcharity.org)
- What treatment do people diagnosed with a meningioma usually have first? (thebraintumourcharity.org)
- If you've just been diagnosed with a meningioma and are about to have treatment, you may want to see what other people's first treatment was. (thebraintumourcharity.org)
- Active monitoring (also known as watch and wait) is frequently the treatment approach used for grade 1 meningiomas. (thebraintumourcharity.org)
- In accordance with the treatment of cow urine, some herbs can rejuvenate body defects (Vata, Pitta,and Cough) and if the body is unevenly distributed, it can cause Meningioma. (cowurine.com)
- If a meningioma is large, higher grade, increasing in size quickly and/or causing swelling in the surrounding brain then treatment is recommended. (targetingcancer.com.au)
- See Brain Lesions: 9 Cases to Test Your Management Skills , a Critical Images slideshow, to review cases including meningiomas, glioblastomas and craniopharyngiomas, and to determine the best treatment options based on the case history and the associated images. (medscape.com)
Stereotactic3
- Moreover, the ongoing advancements in stereotactic radiosurgery procedures, such as the introduction of gamma knife and linear accelerator-based systems, which provide enhanced dose planning algorithms, real-time tumor tracking, and better patient immobilization techniques, are expected to drive the meningioma market in the coming years. (imarcgroup.com)
- Stereotactic radiosurgery is used for surgically inaccessible meningiomas and electively for other meningiomas. (msdmanuals.com)
- If stereotactic radiosurgery is impossible or if a meningioma recurs, radiation therapy may be useful. (msdmanuals.com)
Blood vessels1
- In some cases it is not possible to remove the entire meningioma due to the location of the tumour, resulting in a high risk of causing damage to the surrounding brain/spinal cord or blood vessels. (targetingcancer.com.au)
Spine1
- Its is commonly seen in meningiomas with clear cell histology and those located in the spine . (wikidoc.org)
Commonly3
- Spinal meningioma are tumors that most commonly appear in the mid-back (thoracic) region. (upmc.com)
- Thus far, only radiation has been shown to be related to the formation of meningiomas, but trauma or viruses may also play a role in their growth, though no proof has yet been found for these commonly suggested origins. (microscopyu.com)
- In Los Angeles County, meningioma is reported more commonly in African Americans than in others. (medscape.com)
Risk Factors1
- Background Little is known about occupational risk factors for meningioma. (bmj.com)
Benign brain1
- Participants had at least one reimbursement for high dose cyproterone acetate and no history of meningioma or benign brain tumour, or long term disease status. (bmj.com)
Tuberculum sellae1
- Validation of the superior interhemispheric approach for tuberculum sellae meningioma. (bvsalud.org)
Grade4
- Meningiomas are normally treated according to their grade. (thebraintumourcharity.org)
- Most meningiomas are grade 1 and grow silent. (mayoclinic.org)
- Whether radiation therapy is recommended after surgery depends on how much of the meningioma remains after surgery and the grade of the meningioma. (targetingcancer.com.au)
- The technique used will depend on the size and grade of the meningioma and how close it lies to sensitive structures within the brain or spinal cord. (targetingcancer.com.au)
Brain20
- Meningioma in cats is a type of brain tumor. (vetinfo.com)
- These tumors grow at a faster rate than benign meningiomas and are often characterized by brain invasion. (aans.org)
- On microscopic pathology, some of the characteristic findings of a meningioma include mitotic figures, necrosis , interdigitating processes, and brain invasion. (wikidoc.org)
- Meningiomas are the most common benign tumors of the brain . (wikidoc.org)
- Meningioma can occur anywhere in the brain. (hindawi.com)
- At present, the main method of imaging assessment of meningioma invasion of brain tissue is also MRI. (hindawi.com)
- The dura is opened, and the meningioma can be seen extending en plaque over the surface of the brain. (medscape.com)
- The Meningioma in my Brain is Growing, Now What? (drdiane.com)
- In October of 2013 I went for my routine annual MRI scan to assess the meningioma in my brain. (drdiane.com)
- In recognition of brain injury awareness month, while researching whether a meningioma is an acquired brain injury, I found a place questionably describing brain surgery as a traumatic brain injury, which is of even greater interest to me. (drdiane.com)
- We provide support and valuable resources to all those affected by meningioma brain tumors. (meningiomamommas.org)
- This case demonstrates an uncommon presentation of meningioma, the most common primary brain tumour. (bmj.com)
- Due to meningioma, there is pressure on the nerves of the brain, by which the person has to face many minor problems related to the nervous system. (cowurine.com)
- Meningiomas are the only brain tumor more common among women. (msdmanuals.com)
- Meningiomas compress but do not invade brain parenchyma. (msdmanuals.com)
- Diagnosis of meningiomas is similar to that of other brain tumors, usually by MRI with a paramagnetic contrast agent. (msdmanuals.com)
- They also had me get a MRI where they found a small Meningioma Brain Tumor. (mayoclinic.org)
- We report genomic analysis of 300 meningiomas, the most common primary brain tumors, leading to the discovery of mutations in TRAF7, a proapoptotic E3 ubiquitin ligase, in nearly one-fourth of all meningiomas. (scienceopen.com)
- Growing emphasis on brain tumor research coupled with the advent of new genetic and molecular epidemiologic tools in genetic and molecular epidemiology promise hope for advancing knowledge about the causes of intra-cranial meningioma. (scienceopen.com)
- Radiation therapy may be recommended as an alternative to surgery in certain circumstances, especially if the meningioma is in a high-risk area of the brain or spinal cord which makes an operation difficult. (targetingcancer.com.au)
Radiation3
- The purpose of this study is to compare any good and bad effects of using radiation to treat a meningioma that has been completely removed compared with the more common approach of observing the tumor and treating it with radiation if it returns. (froedtert.com)
- High dose ionizing radiation exposure is an established risk factor for meningioma, and lower doses may also increase risk, but which types and doses are controversial or understudied. (scienceopen.com)
- If a meningioma is not completely removed with surgery, radiation therapy may be recommended after surgery to stop the residual meningioma from growing. (targetingcancer.com.au)
20231
- The 7 major meningioma markets are expected to exhibit a CAGR of 7.2% during 2023-2033. (imarcgroup.com)
Embolization4
- The preoperative embolization of meningiomas supplied by the OPH requires superselective catheterization and the most distal placement of the microcatheter as possible, aiming to protect the central retinal artery of any reflux. (ajnr.org)
- 3 , 14 - 18 This article reports our experiences with the preoperative embolization of meningiomas fed by OPH branches by using Onyx (ev3, Irvine, California). (ajnr.org)
- Preoperative embolization is a safe option for some intracranial meningiomas. (cns.org)
- Characterize the risks and benefits of preoperative embolization for meningiomas. (cns.org)