Signs and symptoms of higher cortical dysfunction caused by organic conditions. These include certain behavioral alterations and impairments of skills involved in the acquisition, processing, and utilization of knowledge or information.

Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors. (1/6)

We have examined neuroanatomical, biochemical and endocrine parameters and spatial learning in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor (nAChR) during ageing. Aged beta2(-/-) mutant mice showed region-specific alterations in cortical regions, including neocortical hypotrophy, loss of hippocampal pyramidal neurons, astro- and microgliosis and elevation of serum corticosterone levels. Whereas adult mutant and control animals performed well in the Morris maze, 22- to 24-month-old beta2(-/-) mice were significantly impaired in spatial learning. These data show that beta2 subunit-containing nAChRs can contribute to both neuronal survival and maintenance of cognitive performance during ageing. beta2(-/-) mice may thus serve as one possible animal model for some of the cognitive deficits and degenerative processes which take place during physiological ageing and in Alzheimer's disease, particularly those associated with dysfunction of the cholinergic system.  (+info)

Schizotypal personality disorder and MRI abnormalities of temporal lobe gray matter. (2/6)

BACKGROUND: Structural MRI data indicate schizophrenics have reduced left-sided temporal lobe gray matter volumes, especially in the superior temporal gyrus (STG) and medial temporal lobe. Our data further suggest a specificity to schizophrenia spectrum disorders of STG volume reduction. Interpretation of research studies involving schizophrenics may be complicated by the effects of exposure to neuroleptics and chronic illness. Sharing the same genetic diathesis of schizophrenics, subjects with schizotypal personality disorder (SPD) offer a unique opportunity to evaluate commonalities between schizophrenia and SPD, particularly as SPD subjects are characterized by cognitive and perceptual distortions, an inability to tolerate close friendships, and odd behavior, but they are not psychotic and so have generally not been prescribed neuroleptics nor hospitalized. Evaluation of brain structure in SPD may thus offer insight into the "endophenotype" common to both disorders. In addition, differences between groups may suggest which are the brain structures of schizophrenics that contribute to the development of psychosis. METHODS: To test the hypothesis of whether SPD subjects might show similar STG abnormalities, STG and medial temporal lobe regions of interest (ROI) were manually drawn on high resolution coronal MRI 1.5 mm thick slices. Images were derived from 16 right-handed male SPD subjects, without regard to family history, and 14 healthy, right-handed, comparison males who did not differ from the SPD group on parental socio-economic status, age, or verbal IQ. RESULTS: As predicted, SPD subjects showed a reduction in left STG gray matter volume compared with age and gender matched comparison subjects. SPD subjects also showed reduced parahippocampal left/right asymmetry and a high degree of disordered thinking. Comparisons with chronic schizophrenics previously studied by us showed the SPD group had a similarity of left STG gray matter volume reduction, but fewer medial temporal lobe abnormalities. CONCLUSIONS: These abnormalities strengthen the hypothesis of a temporal lobe abnormality in SPD, and the similarity of STG findings in schizophrenia and SPD suggest that STG abnormalities may be part of the spectrum "endophenotype." It is also possible that presence of medial temporal lobe abnormalities may help to differentiate who will develop schizophrenia and who will develop the less severe schizophrenia spectrum disorder, SPD.  (+info)

Controlled human exposure to methyl tertiary butyl ether in gasoline: symptoms, psychophysiologic and neurobehavioral responses of self-reported sensitive persons. (3/6)

The 1990 Clean Air Act mandated oxygenation of gasoline in regions where carbon monoxide standards were not met. To achieve this standard, methyl tertiary butyl ether (MTBE) was increased to 15% by volume during winter months in many locations. Subsequent to the increase of MTBE in gasoline, commuters reported increases in symptoms such as headache, nausea, and eye, nose, and throat irritation. The present study compared 12 individuals selected based on self-report of symptoms (self-reported sensitives; SRSs) associated with MTBE to 19 controls without self-reported sensitivities. In a double-blind, repeated measures, controlled exposure, subjects were exposed for 15 min to clean air, gasoline, gasoline with 11% MTBE, and gasoline with 15% MTBE. Symptoms, odor ratings, neurobehavioral performance on a task of driving simulation, and psychophysiologic responses (heart and respiration rate, end-tidal CO(2), finger pulse volume, electromyograph, finger temperature) were measured before, during, and immediately after exposure. Relative to controls, SRSs reported significantly more total symptoms when exposed to gasoline with 15% MTBE than when exposed to gasoline with 11% MTBE or to clean air. However, these differences in symptoms were not accompanied by significant differences in neurobehavioral performance or psychophysiologic responses. No significant differences in symptoms or neurobehavioral or psychophysiologic responses were observed when exposure to gasoline with 11% MTBE was compared to clean air or to gasoline. Thus, the present study, although showing increased total symptoms among SRSs when exposed to gasoline with 15% MTBE, did not support a dose-response relationship for MTBE exposure nor the symptom specificity associated with MTBE in epidemiologic studies.  (+info)

"Cognitive dysmetria" as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical-cerebellar circuitry? (4/6)

Earlier efforts to localize the symptoms of schizophrenia in a single brain region have been replaced by models that postulate a disruption in parallel distributed or dynamic circuits. Based on empirical data derived from both magnetic resonance and positron emission tomography, we have developed a model that implicates connectivity among nodes located in prefrontal regions, the thalamic nuclei, and the cerebellum. A disruption in this circuitry produces "cognitive dysmetria," difficulty in prioritizing, processing, coordinating, and responding to information. This "poor mental coordination" is a fundamental cognitive deficit in schizophrenia and can account for its broad diversity of symptoms.  (+info)

Integrating schizophrenia. (5/6)

A neuropsychological theory of the positive symptoms of schizophrenia proposed by J.A. Gray et al. is reviewed in light of subsequent evidence from studies of latent inhibition in clinical populations, healthy volunteers, and rats. It is clear that disrupted latent inhibition is associated with psychosis, but it is uncertain whether this is a state or a trait marker. Much evidence indicates that a similar disruption in latent inhibition can be provoked in rats by excess release of dopamine in the nucleus accumbens, and conversely, that potentiation of latent inhibition occurs when dopaminergic transmission is blocked in this structure. The projection from the hippocampal system to the nucleus accumbens also plays a role in latent inhibition. The theory, therefore, is broadly supported by recent findings. The resulting model of schizophrenia is discussed in relation to the contents of consciousness, positive psychotic symptoms, and alternative theories.  (+info)

Dysfunctions in multiple interrelated systems as the neurobiological bases of schizophrenic symptom clusters. (6/6)

The absence of an animal model that accurately approximates schizophrenia limits current research into the pathophysiology of this disorder. Obviously, the cognitive disturbances associated with schizophrenia are difficult to evaluate in laboratory animals. Nonetheless, animal studies have provided insight into the anatomy and physiology of the brain systems that have been implicated in schizophrenia. These studies also suggest how brain systems may be involved in information processing in normal and pathological conditions. Thus, a careful assessment of the properties and functions of the brain regions suggested to be involved in schizophrenic symptoms has been a primary objective in several laboratories. In this review, we discuss the interactions among the brain regions implicated in schizophrenia--the ventral striatum, prefrontal cortex, hippocampus, and dopamine systems--and provide an integrative model linking altered function in these regions with specific clusters of symptoms of schizophrenia.  (+info)

Neurobehavioral manifestations refer to the observable behaviors and symptoms that result from an underlying neurological disorder or injury. These manifestations can include cognitive, emotional, and motor impairments, such as difficulties with attention, memory, mood regulation, communication, and coordination. The specific neurobehavioral manifestations exhibited can vary widely depending on the location and extent of the neurological damage or dysfunction. They are often assessed and diagnosed by healthcare professionals trained in neuropsychology, neurology, or related fields.

Neurobehavioral Manifestations of Neurological Diseases: Diagnosis and Treatment. Neurologic Clinics. Volume 34, February 2016 ... Along with his co-investigators, he has helped to understand the pathophysiology of many neurobehavioral disorders such as ...
Non musculoskeletal manifestations of DMD occur. There is a higher risk of neurobehavioral disorders (e.g., ADHD), learning ...
Fallon BA, Nields JA, Parsons B, Liebowitz MR, Klein DF (July 1993). "Psychiatric manifestations of Lyme borreliosis". The ... Pituitary Macroadenomas eMedicine Meyers CA (1998). "Neurobehavioral functioning of adults with pituitary disease". ... Bohrer T, Krannich JH (2007). "Depression as a manifestation of latent chronic hypoparathyroidism". World Journal of Biological ... that is largely unrecognized in clinical settings and thus often untreated due to ignorance of the clinical manifestations of ...
... neurobehavioral manifestations MeSH C23.888.592.604.080 - apraxias MeSH C23.888.592.604.115 - catatonia MeSH C23.888.592.604. ... neuromuscular manifestations MeSH C23.888.592.608.250 - fasciculation MeSH C23.888.592.608.500 - muscle cramp MeSH C23.888. ...
... in the present study we demonstrated that all polygraphic and neurobehavioral manifestation of SWS, including SWA, can be ...
... in the present study we demonstrated that all polygraphic and neurobehavioral manifestation of SWS, including SWA, can be ...
... in the present study we demonstrated that all polygraphic and neurobehavioral manifestation of SWS, including SWA, can be ...
Other reasons for the manifestation of Bell's Mania, points at the use of stimulant drugs in excessive amounts and also ... Bell's mania, also known as delirious mania, refers to an acute neurobehavioral syndrome. This is usually characterized by an ... Psychostimulant users as well as individuals experiencing severe manic episodes are more prone to the manifestation of this ...
Zis P, Hadjivassiliou M (26 February 2019). "Treatment of Neurological Manifestations of Gluten Sensitivity and Coeliac Disease ... Neurobehavioral Function, and Neuroinflammation. International Review of Neurobiology. Vol. 148. pp. 101-168. doi:10.1016/bs. ...
Losurdo G, Principi M, Iannone A, Amoruso A, Ierardi E, Di Leo A, Barone M (April 2018). "Extra-intestinal manifestations of ... Alasmari F (April 2020). "Caffeine induces neurobehavioral effects through modulating neurotransmitters". Saudi Pharmaceutical ... There are two primary manifestations of catatonic behavior. The classic presentation is a person who does not move or interact ... but they are now the most common manifestation of schizophrenia, although rates vary between cultures and regions. Auditory ...
Kleeblattschädel is a feature of several conditions and can also be seen in nonsyndromic manifestations. True pansynostosis can ... a review of neurobehavioral research and theory". Journal of Pediatric Psychology. 29 (8): 651-68. doi:10.1093/jpepsy/jsh068. ... abnormalities in the skull base and neurobehavioral impairment. When the ICP is elevated the following symptomes may occur: ...
... neurological disease characteristics and the contribution of neurological manifestations to outcome. While discussing the ... brain stimulation with weak direct currents as a promising tool in the context of human neuroscience and neurobehavioral ... "An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID)". ...
Spear, L.P. (June 2000). "The adolescent brain and age-related behavioral manifestations". Neuroscience & Biobehavioral Reviews ... Wahlstrom, Dustin; White, Tonya; Luciana, Monica (April 2010). "Neurobehavioral evidence for changes in dopamine system ...
A paper by Feldman and colleagues described neurobehavioral effects in a 57-year-old house painter with regular exposure to ... nonspecific manifestations, relative infrequency as individual entities, and frequent lack of specific diagnostic testing. Yet ... Neurobehavioral Toxicology. In: Ramachandran V.S. (ed); Encyclopedia of the Human Brain. New York, Elsevier Science, Vol. 3, pp ... treatment of the common clinical manifestation of depression if present, and counselling for the provision of life strategies ...
... on neurobehavioral abnormalities in mice found, that the inhibition of DNA methylation by 5-AzaC treatment causes ... activity of 5-azacytidine during treatment of a HTLV-1 positive myelodysplastic syndrome with autoimmune manifestations". ... "A single day of 5-azacytidine exposure during development induces neurodegeneration in neonatal mice and neurobehavioral ...
Of non-autonomic manifestations, deviation of eyes to the right or left occurred before or after vomiting without any apparent ... Children with pre-existing neurobehavioral disorders tend to be pharmacoresistant and have frequent seizures though these also ... The first clinical manifestation which appeared long (1-10 minutes) after the electrical onset, usually consisted of opening of ... Other autonomic manifestations include pallor (or, less often, flushing or cyanosis), mydriasis (or, less often, miosis), ...
Mariani, Laura (2007). "The Renal Manifestations of Thyroid Disease". Journal of the American Society of Nephrology. 23 (1): 22 ... Concussive brain trauma neurobehavioral impairment and maladaptation (Second ed.). Boca Raton, FL: CRC Press. p. 322. ISBN 978- ...
ISBN 0-679-76183-7. Depue, R.A., & Morrone-Strupinsky, J.V. (2005). A neurobehavioral model of affiliative bonding: ... and Psychological Manifestations. New York: Springer. ISBN 0-7923-7478-9 Ben-Amos, I.K. (1997). "Human Bonding: Parents and ...
Initial manifestations of bradykinesia are problems when performing daily life tasks requiring fine motor control such as ... Non-motor symptoms, which include dysautonomia, cognitive and neurobehavioral problems, and sensory and sleep difficulties, are ... Rigidity may be associated with joint pain, with such pain being a frequent initial manifestation of the disease. When limbs of ... Gait freezing, also called motor blocks, is a manifestation of akinesia. Gait freezing is characterized by a sudden inability ...
Epilepsy is a neuronal disorder with multifactorial manifestations. It is a noncontagious illness and is usually associated ... Psychogenic non-epileptic seizures (PNES) are described as neurobehavioral conditions or "psychogenic illnesses" which occur ...
Surgery can resolve psychiatric manifestations in selected cases. Arachnoid cysts are seen in up to 1.1% of the population with ... Cullum CM, Heaton RK, Harris MJ, Jeste DV (October 1994). "Neurobehavioral and neurodiagnostic aspects of late-onset psychosis ...
Gehring WJ, Coles MG, Meyer DE, Donchin E (1995). "A brain potential manifestation of error-related processing.". In Karmos G, ... "A Neurobehavioral Mechanism Linking Behaviorally Inhibited Temperament and Later Adolescent Social Anxiety". Journal of the ...
... appears to be capable of precipitating the acute manifestations of cardio-vascular diseases (atherothrombosis) ... Learning difficulties, developmental delays, executive function problems, and neurobehavioral effects. Animal models suggest a ...
In: Neurobehavioral Problems in Epilepsy, SmithD., TreimanD. and Trimble M. R. (Eds.). New York: Raven Press. pp. 127-42. Russo ... In this instance, the pattern of episodic disorder remission and abrupt manifestation of psychiatric behaviors that are present ...
FBLN1 is responsible for synpolydactyly as well as its contribution to the neurological manifestations (OMIM 608180). Table of ... "Neurobehavioral Profile and Brain Imaging Study of the 22q13.3 Deletion Syndrome in Childhood". Pediatrics. 122 (2): e376-e382 ... Any abnormal genetic variation in the q13 region that presents with significant manifestations (phenotype) typical of a ... Affected individuals present with a broad array of medical and behavioral manifestations (tables 1 and 2). Patients are ...
... a not-unusual manifestation of PCP toxicity. PCP is well known for its primary action on the NMDA receptor, an ionotropic ... Neurobehavioral Pharmacology. New York: Plenum Publishing Corporation. pp. 579-587. ISBN 978-1-4757-2913-9. "NIDA InfoFacts: ...
Jurewicz J, Hanke W (2008). "Prenatal and childhood exposure to pesticides and neurobehavioral development: review of ... as windows of varying susceptibility dictate disease manifestation. Several studies suggest that higher levels of pesticides in ...
Often reproductive disorders are the only manifestation of undiagnosed celiac disease and most cases are not recognized. ... Short-term neonatal outcomes in methamphetamine babies show small deficits in infant neurobehavioral function and growth ...
The most common manifestation of neonatal strokes are seizures, but other manifestations include lethargy, hypotonia, apnoea, ... and neurobehavioral parameters can be tested. Some animals that meet these criteria are sheep, non-human primates, rabbits, ...
Children born to mothers with undertreated HG have a fourfold increase in neurobehavioral diagnoses. Though the exact cause of ... a manifestation of a subconscious desire to terminate the pregnancy, or being an attention-seeking behavior. These erroneous ...
"Neurobehavioral Manifestations" by people in this website by year, and whether "Neurobehavioral Manifestations" was a major or ... "Neurobehavioral Manifestations" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Neurobehavioral Manifestations" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Neurobehavioral Manifestations". ...
Update on the Clinical, Radiographic, and Neurobehavioral Manifestations in FXTAS and FMR1 Premutation Carriers. In: Cerebellum ... Update on the Clinical, Radiographic, and Neurobehavioral Manifestations in FXTAS and FMR1 Premutation Carriers. Cerebellum. ... Dive into the research topics of Update on the Clinical, Radiographic, and Neurobehavioral Manifestations in FXTAS and FMR1 ... Update on the Clinical, Radiographic, and Neurobehavioral Manifestations in FXTAS and FMR1 Premutation Carriers. / Hall, ...
Intellectual disability and neurobehavioral manifestations. It is estimated that as many as 50% of individuals with OFD1 have ... Manifestation/Concern. Treatment. Considerations/Other. Oral manifestations *. Reconstructive surgery for clefts of lip &/or ... Treatment of Manifestations. Table 6. Oral-Facial-Digital Syndrome Type I: Treatment of Manifestations ... Kidney manifestations. Renal cysts can develop from both tubules and glomeruli. The age of onset is most often in adulthood, ...
Neurobehavioral Manifestations of Neurological Diseases: Diagnosis and Treatment. Neurologic Clinics. Volume 34, February 2016 ... Along with his co-investigators, he has helped to understand the pathophysiology of many neurobehavioral disorders such as ...
Categories: Neurobehavioral Manifestations Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
The recognition of the adolescent period as a time of increased drug use and potential vulnerability to the neurobehavioral ... Spear LP (2000) The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24(4):417-463 ... Impact of Amphetamine Exposure During Adolescence on Neurobehavioral Endpoints. *Steven R. Boomhower. 3,4 ... The recognition of the adolescent period as a time of increased drug use and potential vulnerability to the neurobehavioral ...
Other neurobehavioral manifestations include attention-deficit-hyperactivity disorder, obsessive-compulsive disorder, poor ... These include the lack of a definitive diagnosis of TS; the variable manifestations of the syndrome; the methods employed in ...
Neurobehavioral Manifestations [F01.700]. *Polydipsia, Psychogenic [F01.700.812]. Below are MeSH descriptors whose meaning is ...
Neurobehavioral and imaging studies have revealed that there are significant differences in clinical manifestations and ...
The typical manifestations of ADHD, attention difficulties and hyperactivity, cause impairment in social and academic ... Attention-deficit hyperactivity disorder (ADHD) is a neurobehavioral development disorder affecting an estimated 6% to 9% of ...
Although neurobehavioral development may be impaired in children with BLLs as low as 10 ug/dL (6-8), overt manifestations of ... The child had no apparent clinical manifestations, and his mother was unaware of obvious sources of lead exposure, including ...
Neurobehavioral effects have been noted experimentally following MP exposure in experimental animals; it is logical that this ... to acute cholinergic crisis with severe manifestations of the above symptoms. Direct experience in locations where indoor ... These symptoms can range from subtle neurobehavioral disturbances to nonspecific symptoms such as nausea; diarrhea; dizziness; ... blood ChE inhibition correlates with nervous system AChE inhibition or how much AChE depression is required for neurobehavioral ...
Although neurobehavioral development may be impaired in children with BLLs as low as 10 ug/dL (6-8), overt manifestations of ... The child had no apparent clinical manifestations, and his mother was unaware of obvious sources of lead exposure, including ...
Neurobehavioral deficits and Parkinsonism in occupations with manganese exposure: a review of methodological issues in the ... The effects of sustained low-concentration exposures to Mn are consistent with the manifestations of early manganism, i.e., ... Exposure to manganese (Mn) is associated with neurobehavioral effects. There is disagreement on whether commonly occurring ... Twenty-eight studies show an exposure-response relationship between Mn and neurobehavioral effects, including 11 with ...
Neurobehavioral Manifestations 100% * Migraine Disorders 83% * Headache 59% * Health Care Outcome Assessment 54% ...
Neurobehavioral Manifestations 69% * Symptom Flare Up 32% * Is maternal psychopathology related to obesigenic feeding practices ...
Fellows learn how to comprehensively evaluate and treat patients with complex neurobehavioral problems associated with a range ... Fellows are trained in neurobiological bases and treatment of cognitive, behavioral, and neuropsychiatric manifestations of ... neurobehavioral disorders, multiple sclerosis and other degenerative conditions. Fellows will receive training in both ...
Neurobehavioral Manifestations Medicine & Life Sciences 100% * Amyloid Medicine & Life Sciences 78% * Cognitive Dysfunction ...
A neurobehavioral syndrome associated with bilateral medial temporal lobe dysfunction. Clinical manifestations include oral ... A neurobehavioral syndrome associated with bilateral medial temporal lobe dysfunction. Clinical manifestations include oral ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
Physiological manifestations; Memory; Emotions; Neurobehavioral manifestations; Nervous system; Autonomic. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
NEUROBEHAVIORAL MANIFESTATIONS. CONVULSIONS, FEBRILE. SEIZURES, FEBRILE. CYSTEINE PROTEINASES. CYSTEINE ENDOPEPTIDASES. ...
  • Neurobehavioral and imaging studies have revealed that there are significant differences in clinical manifestations and neurological symptoms between MCS and VS ( Istace, 2022 ). (frontiersin.org)
  • Investigations with adequate study design and exposure assessment revealed consistent neurobehavioral effects and attributable subclinical and clinical signs and symptoms of impairment. (cdc.gov)
  • Along with his co-investigators, he has helped to understand the pathophysiology of many neurobehavioral disorders such as spatial neglect, apraxia, disorders of emotional communication, aphasia and amnestic disorders. (wikipedia.org)
  • Fellows learn how to comprehensively evaluate and treat patients with complex neurobehavioral problems associated with a range of disorders, including neuropsychological and biological aspects of dementia, especially Alzheimer's disease. (brighamandwomens.org)
  • Clinical experience in the joint Brigham and Mass General Neuropsychology Fellowship will consist of adult neurological cases, including dementia, epilepsy, brain tumor, developmental syndromes, neurobehavioral disorders, multiple sclerosis and other degenerative conditions. (brighamandwomens.org)
  • In addition, Spann is interested in non-cognitive manifestations of dementia such as behavioral changes and sleep disorders. (rxwiki.com)
  • He completed his residency at Cleveland Clinic followed by fellowship training in both movement and neurobehavioral disorders. (rxwiki.com)
  • She hopes her research can contribute to further understanding of ASLD and other neurobehavioral disorders. (psu.edu)
  • The child had no apparent clinical manifestations, and his mother was unaware of obvious sources of lead exposure, including traditional ethnic remedies. (cdc.gov)
  • Neuropsychological evaluation included a neurobehavioral status examination, face-to-face neurocognitive testing, and computer-administered measures. (cambridge.org)
  • Sandifer syndrome, named after neurologist Paul Sandifer, was first reported by Marcel Kinsbourne in 1962, who noted an upper gastrointestinal disorder that occurs in children and adolescents with neurological manifestations. (asploro.com)
  • Assess developmental progress, educational needs, and behavioral manifestations at each visit. (nih.gov)
  • Serotonin influences the growth and development of the nervous system, as well as its behavioral manifestations. (scite.ai)
  • A neurobehavioral syndrome associated with bilateral medial temporal lobe dysfunction. (bvsalud.org)
  • Children with ND-PAE have neurodevelopmental, neurobehavioral, or mental health effects of prenatal alcohol exposure with or without cardinal facial dysmorphia and/or significant growth problems (height, weight, smaller head circumference of less than 10th percentile) associated with Fetal Alcohol Syndrome (FAS) physical features. (aap.org)
  • Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE), Alcohol-Related Neurodevelopmental Disorder (ARND), Fetal Alcohol Syndrome (FAS) and Partial Fetal Alcohol Syndrome (PFAS), and Alcohol-Related Birth Defects (ARBD). (aap.org)
  • Tourette syndrome is a neurobehavioral disorder chiefly manifested by motor and phonic tics. (medlink.com)
  • 201 ). Once considered a rare psychiatric curiosity, Tourette syndrome is now recognized as a relatively common neurobehavioral disorder. (medlink.com)
  • Sandifer syndrome is a neurobehavioral disorder that causes a series of paroxysmal dystonic movements in association with gastroesophageal reflux and, in some cases, with hiatal hernia. (asploro.com)
  • The diagnosis of Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE) was introduced in the 5th edition of the Diagnostic and Statistical Manual (DSM) of the American Psychiatric Association in 2013. (aap.org)
  • Other neurobehavioral manifestations include attention-deficit-hyperactivity disorder, obsessive-compulsive disorder, poor impulse control, and other behavioral problems. (medscape.com)
  • Neurobehavioral Manifestations" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
  • The recognition of the adolescent period as a time of increased drug use and potential vulnerability to the neurobehavioral effects of repeated drug use has existed for many years. (springer.com)
  • Exposure to manganese (Mn) is associated with neurobehavioral effects. (cdc.gov)
  • Twenty-eight studies show an exposure-response relationship between Mn and neurobehavioral effects, including 11 with continuous exposure metrics and six with three or four levels of contrasted exposure. (cdc.gov)
  • The effects of sustained low-concentration exposures to Mn are consistent with the manifestations of early manganism, i.e., consistent with parkinsonism. (cdc.gov)
  • The topics discussed include phenotype-genotype relationships, neurobehavioral function, and updates on FXTAS genetics and imaging. (northwestern.edu)
  • Corinna's research uses C. elegans with a reduced adenylosuccinate lyase activity to study neurobehavioral manifestations associated with the human disease adenylosuccinate lyase deficiency (ASLD). (psu.edu)
  • Using this model, seeks to understand the connection between cellular and metabolic changes seen in this disease and the neurobehavioral phenotypes observed. (psu.edu)
  • Neurobehavioral checks, hematoma volume, and brain water content were evaluated after ICH. (biotech2012.org)
  • Investigations with adequate study design and exposure assessment revealed consistent neurobehavioral effects and attributable subclinical and clinical signs and symptoms of impairment. (cdc.gov)
  • July 13, 2011 - Secondhand smoke exposure in the home is associated with an increased risk for neurobehavioral disorders among children younger than 12 years of age, according to new research. (medscape.com)
  • To examine common pediatric neurobehavioral disorders, including attention-deficit/hyperactivity disorder, learning disabilities, and conduct disorders, in children exposed to secondhand smoke in the home, the investigators accessed the National Survey of Children's Health conducted between April 2007 and July 2008 and analyzed 55,358 children younger than 12 years of age. (medscape.com)
  • The researchers estimate that 274,000 cases of neurobehavioral disorders might have been prevented, had those households been smoke-free. (medscape.com)
  • He added that it is important to highlight that these neurobehavioral disorders are very preventable. (medscape.com)
  • Along with his co-investigators, he has helped to understand the pathophysiology of many neurobehavioral disorders such as spatial neglect, apraxia, disorders of emotional communication, aphasia and amnestic disorders. (wikipedia.org)
  • This PA, Viral Load in Brain and Neurobehavioral Correlates, is related to the priority areas of mental health and mental disorders. (nih.gov)
  • Twenty-two patients have been described with overlapping neurobehavioral disturbances including developmental delay, intellectual disability of variable degree, seizures, motor coordination disorder, behavioral/emotional disturbances, and autism spectrum disorders. (blogspot.com)
  • However, occasionally, the expert responsible for cognitive rehabilitation is a clinical psychologist, due to his/her expertise and long-term clinical training in cognitive, behavioral and psychopathological manifestations seen in brain injuries or mental disorders. (hnps.gr)
  • This new number is indented under WL 340 Neurologic manifestations (General or not elsewhere classified). (nih.gov)
  • One is the appearance of neurobehavioral deficits. (nih.gov)
  • Neurobehavioral deficits and Parkinsonism in occupations with manganese exposure: a review of methodological issues in the epidemiological literature. (cdc.gov)
  • Brain tumours are commonly associated with neurological deficits but rarely psychiatric manifestations may be seen. (nerdyseal.com)
  • PURPOSE The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) invites applications for research on the pathogenesis of neuropsychiatric manifestations of systemic lupus erythematosus (NP-SLE) and on the development of innovative therapeutic approaches and diagnostics for this form of lupus. (nih.gov)
  • This RFA is based in part on the scientific opportunities identified in the conference "CNS Manifestations of Systemic Lupus Erythematosus. (nih.gov)
  • Pai S, Kramer N, Rosenstein ED. Malignant Catatonia as the Presenting Manifestation of Systemic Lupus Erythematosus. (jefferson.edu)
  • That research led to a recently completed study of the use of an mTOR inhibitor to improve neurobehavioral and cognitive function in TSC. (tandconsortium.org)
  • Cognitive rehabilitation refers to a non-pharmaceutical neurobehavioral treatment of cognitive functioning, behavior and mood, which might have been disrupted due to brain injury or brain disease. (hnps.gr)
  • Only 20 patients with deletions of 18q12.2 have been reported in the literature and the associated phenotype includes borderline intellectual disability, behavioral problems, seizures, obesity, and eye manifestations. (blogspot.com)
  • Seizures are the other common non-specific manifestation of any brain tumor, seen in ~20% cases of GBM at presentation. (medscape.com)
  • A rare, genetic, syndromic intellectual disability disorder characterized by craniofacial features, global developmental delay, intellectual disability and variable neurobehavioral abnormalities (autism spectrum disorder, aggressiveness, and self-injury). (sjelden.no)
  • This study, representing a first, prospective, detailed characterization of DDX3X syndrome, extends our understanding of the neurobehavioral phenotype. (biomedcentral.com)
  • Some studies suggest that NPS phenotype may be more extensive than previously recognized, including neurologic and neurobehavioral aspects. (medscape.com)
  • Neuropsychiatric manifestations in these patients have great bearing on the quality of life which has now become a major concern in the management of the brain tumors. (nerdyseal.com)
  • Our study illustrates the utility of high-resolution genome-wide techniques in identifying neurodevelopmental and neurobehavioral genes, and it adds to the growing evidence, including a transgenic mouse model, that CELF4 is important for human brain development. (blogspot.com)
  • I mused that perhaps the same genetic vulnerability that leads to ADHD in childhood could lead to the manifestation of psychosis in teenage/adulthood. (the-mouse-trap.com)
  • Dr. Harris is currently the director of the Epigenetics Clinic at Kennedy Krieger Institute and a Neurology/Medical consultant to the Neurobehavioral Unit at Kennedy Krieger Institute. (beckfahrner.org)
  • Psychotic manifestations are usually not seen in primary brain tumor patients. (nerdyseal.com)
  • These manifestations may be prominent, but at times subtle, thus they are often not reported by patients or physicians as related to the diabetes. (biu.ac.il)
  • In a significant percentage of patients, sudden cardiac arrest is the first manifestation of heart disease. (merckmanuals.com)
  • The degree to which organic causes are responsible for psychiatric manifestations is difficult to determine hence accurate diagnosis in these cases can be a diagnostic challenge. (nerdyseal.com)
  • As a result of this analysis, a new class number WL 340.1 was created for Neurobehavioral Manifestations. (nih.gov)
  • The direct link between the presence of virus in the brain and the resulting neurobehavioral impairments is not clear. (nih.gov)
  • Psychotic manifestation as an initial presentation of brain tumor is a rare manifestation of the primary disease. (nerdyseal.com)
  • Following surgical removal of the brain tumor, psychotic manifestations disappeared. (nerdyseal.com)
  • Furthermore, the metabolic mechanism for such manifestations has been inconsistent and difficult to interpret in practical clinical care, as reported in several reviews on the topic of brain and T1DM. (biu.ac.il)
  • However, new technological methods for brain assessment, as well as the introduction of continuous glucose monitoring, provide new insights and information regarding brain related manifestations and glycemic variability and control parameters, which may impact the clinical care of children and youth with T1DM. (biu.ac.il)
  • The primary objective of this evaluation is to undertake a scoping review of existing human, animal, and in vitro studies and identify the literature relevant to paraquat exposure and neurobehavioral and neuropathological endpoints associated with Parkinson's disease. (nih.gov)
  • Manifestations of lower level exposures can take two forms. (nih.gov)
  • There is disagreement on whether commonly occurring exposures in welding , ferroalloy, and other industrial processes produce neurologically significant neurobehavioral changes representing parkinsonism. (cdc.gov)
  • The effects of sustained low-concentration exposures to Mn are consistent with the manifestations of early manganism, i.e., consistent with parkinsonism. (cdc.gov)
  • During the renewal period, we propose to examine the persistence of and/or the novel manifestation of beneficial neurobehavioral effects of the prenatal multimicronutrient intervention trial, to examine the role of postnatal child nutrition in FASD, an to explore genetic and epigenetic factors as biomarkers of maternal exposure and risk modification among alcohol consuming pregnant women. (nih.gov)
  • Pediatric out-of-hospital cardiac arrest characteristics and their association with survival and neurobehavioral outcome. (merckmanuals.com)
  • Secondhand smoke is not the only causative factor of neurobehavioral disease in children," Dr. Alpert said. (medscape.com)
  • Her early work focused on structural MRI findings and their correlation with neurobehavioral findings in children with TSC. (tandconsortium.org)
  • With MeSH 2021, Mania is a new term treed under Neurobehavioral Manifestations (classed at WL 340). (nih.gov)
  • A review of all the terms classed under Neurobehavioral Manifestations was conducted to see if there was enough literary warrant to create a new class number for this parent term. (nih.gov)
  • Cite this: Secondhand Smoke Boosts Neurobehavioral Problems in Kids - Medscape - Jul 13, 2011. (medscape.com)