Neurocytoma
Cerebral Ventricle Neoplasms
Brain Neoplasms
Extraventricular neurocytoma with ganglionic differentiation associated with complex partial seizures. (1/46)
We report an unusual case of extraventricular ("cerebral") neurocytoma with ganglion cells located in the right temporal lobe in a 9-year-old girl with complex partial seizures and precocious puberty. CT showed a calcified mass with central cystic zones. MR imaging showed a markedly hyperintense predominately solid tumor on both T1- and T2-weighted images, without appreciable contrast enhancement. Cerebral neurocytomas are histologically benign and radical surgery is curative; they should be included in the differential diagnosis of temporal lobe tumors in children. (+info)Central neurocytoma with malignant course. Neuronal and glial differentiation and craniospinal dissemination. (2/46)
Central neurocytoma is a benign neuronal tumor of young adults in the lateral cerebral ventricles with characteristic X ray and light microscopic findings. In many respects typical central neurocytoma is reported below, with recurrence in the third month requiring reoperation. Death ensued in the fifth postoperative month. Subsequent histology proved progressive vascular proliferation and increasing, unusual glial differentiation of the neuronal tumor. At autopsy tumorous seeding blocked the liquor circulation. A thin tumorous layer covered the surface of all ventricles, the cerebellum and medulla oblongata. The GFAP positive cells out-numbered the synaptophysin positive ones. Increase of GFAP positivity and vascular proliferation of the central neurocytoma may be alarming signs suggesting a malignant course in addition to the other atypical features. (+info)Gamma knife radiosurgery of recurrent central neurocytomas: a preliminary report. (3/46)
OBJECTIVES: A series of three recurrent central neurocytomas treated by gamma knife radiosurgery (GKRS), which were initially totally resected, are described. Up to now, no reports exist on this treatment modality for this rare tumour entity. METHODS: Three male patients, aged between 20 and 25 years, presented with large intraventricular tumours. Total tumour removal was achieved by a single surgical procedure (one patient) or two operations (two patients). Neuropathological investigation showed a central neurocytoma, immunohistochemically all three tumours expressed a neuronal antigenic profile typical for neurocytomas, and the MIB-1 proliferation index ranged from 2.4% to 8.7%. Each patient experienced a tumour recurrence after 5 to 6 years. The recurrence was multifocal in two and a singular tumour mass in one patient. Gamma knife radiosurgery was performed. The tumours were enclosed within the 30% to 60% isodoseline, and delivered a tumour marginal dose of 9.6 to 16 Gy. During the follow up period, the patients were tested clinically and the volume of the tumours was measured on MRI. RESULTS: Within follow up periods of 1 to 5 years, control MRI showed a significant decrease of the tumour mass in all cases. None of the patients developed new neurological symptoms after GKRS. Two patients returned to work in their previous employment, whereas one patient remained permanently disabled due to a pre-existing visual impairment and abducens palsy. CONCLUSION: GKRS proved to be a useful tool in the treatment of recurrent central neurocytomas. Tumour control and even tumour shrinkage can be achieved with a single procedure and a low risk of morbidity. (+info)MR imaging and histopathologic findings of a case of cerebral ganglioneurocytoma. (4/46)
We report a case of ganglioneurocytoma manifesting as a complex partial seizure in a young adult male. MR images depicted a well-marginated cystic mass with a heterogeneous solid portion abutting the dura in the parietal lobe. The solid portion showed minimal heterogeneous enhancement, and pressure erosion of the overlying calvarium had occurred. Following gross total resection, the clinical outcome was satisfactory, with no further seizures, and during the five-year follow-up period, the tumor did not recur. (+info)Cerebellar liponeurocytoma: a newly recognized clinico-pathological entity. (5/46)
The term "cerebellar liponeurocytoma", recently adopted by the World Health Organization Working Group (WHO), replaced many other different terms used up to now to give name to this rare tumor. To our knowledge, less than 20 cases have been related up to now under different names like as "lipomatous medulloblastoma, lipidized medulloblastoma, neurolipocytoma, medullocytoma and lipomatous glioneurocytoma". The new nomenclature eliminates the word "medulloblastoma", reinforces its benign character, and includes it in the category of glioneuronal tumors. We describe an addictional case of this distinct clinico-pathological entity removed from the right cerebellar hemisphere of a 53-year-old woman. With the present case report, we hope to contribute to the knowledge on the diagnostic and prognostic implications derived from the finding of mature adipose-like tissue within a medulloblastomatous tumour. (+info)Angiographic characteristics of central neurocytoma suggest the origin of tumor. (6/46)
The authors retrospectively analyzed the angiographic findings performed in 17 cases with central neurocytoma to document the angiographic characteristics and suggested the origin of tumor based on the angiographic findings. Their medical records and radiological investigations were reviewed and cerebral angiographies were thoroughly examined in arterial, capillary, and venous phases. In ten cases, marked or moderate tumor staining was found whereas the staining was either scanty or absent in seven cases. In the ten cases showing marked or moderate tumor staining, the feeding vessels were originated from the ipsilateral carotid and/or vertebro-basilar system. In the venous phase, the ipsilateral thalamostriate vein, tortuous and enlarged, was elevated, and the internal cerebral vein was depressed. Thus, the venous angle of the ipsilateral side was widened at an irregular contour. Based on the characteristic displacement and the increased size of the associated venous system, it is suggested that the central neurocytoma might originate from a neuronal cell mass of the subependymal zone located on the floor of the lateral ventricle around the foramen of Monro rather than from the septum pellucidum. (+info)Liponeurocytoma of the cerebellum--a case report. (7/46)
We report the characteristic neuropathological features of a rare case of cerebellar liponeurocytoma in a 62-year-old female. The tumor has a low proliferative potential and carries a favorable prognosis. (+info)Peritoneal dissemination from central neurocytoma: case report. (8/46)
OBJECTIVE: Central neurocytoma is a low grade tumor of neuroglial origin and a relatively new histological entity. Only a few cases have been reported and its biological behavior is still uncertain. Some cases have shown an aggressive behavior (local recurrence, malignant dedifferentiation or CSF dissemination) and challenged the initial view of its relative benignity. A case of central neurocytoma with peritoneal dissemination is presented. CASE: A six years-old boy with recurrent neurocytoma of III ventricle and left thalamus showed fast growth of tumor rest and ascites three and a half years after subtotal removal of the lesion. Tumor cells were identified in the ascitic fluid and implanted in the peritoneum. Chemotherapy was initiated immediately after diagnosis of peritoneal dissemination (etoposide, carboplatin, doxorubicin and cyclophosphamide). The patient developed metabolic imbalance and respiratory failure due to rapid formation of ascitic fluid and died 3 days after the diagnosis of peritoneal dissemination was established. CONCLUSION: Central neurocytoma is a low grade tumor with low values of the proliferative index in the majority of cases. In spite of that, some tumors may present a very aggressive behavior and extraneural dissemination. Evaluation of proliferative index may be a guideline parameter for planning adjuvant therapies after surgical treatment in selected cases. Extraneural dissemination may occur in some cases specially in patients with ventriculoperitoneal shunt. (+info)Neurocytoma is a rare, typically benign (non-cancerous) intraventricular brain tumor originating from the ventricles of the brain. It mainly affects adults in their third to fifth decade of life and accounts for less than 1% of all primary brain tumors. Histologically, neurocytomas are characterized by uniform round cells with salt-and-pepper chromatin and scant cytoplasm, resembling neurons. They usually arise in the lateral ventricles, particularly around the foramen of Monro, and can cause obstructive hydrocephalus due to their location. Neurocytomas are generally slow-growing tumors, but they can sometimes display more aggressive behavior. Complete surgical resection is the treatment of choice when feasible, although radiation therapy and chemotherapy may also be considered in specific cases.
Cerebral ventricle neoplasms refer to tumors that develop within the cerebral ventricles, which are fluid-filled spaces in the brain. These tumors can arise from various types of cells within the ventricular system, including the ependymal cells that line the ventricles, choroid plexus cells that produce cerebrospinal fluid, or other surrounding tissues.
Cerebral ventricle neoplasms can cause a variety of symptoms depending on their size and location, such as headaches, nausea, vomiting, vision changes, imbalance, weakness, or difficulty with mental tasks. The treatment options for these tumors may include surgical resection, radiation therapy, and chemotherapy, depending on the type and extent of the tumor. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.
Brain neoplasms, also known as brain tumors, are abnormal growths of cells within the brain. These growths can be benign (non-cancerous) or malignant (cancerous). Benign brain tumors typically grow slowly and do not spread to other parts of the body. However, they can still cause serious problems if they press on sensitive areas of the brain. Malignant brain tumors, on the other hand, are cancerous and can grow quickly, invading surrounding brain tissue and spreading to other parts of the brain or spinal cord.
Brain neoplasms can arise from various types of cells within the brain, including glial cells (which provide support and insulation for nerve cells), neurons (nerve cells that transmit signals in the brain), and meninges (the membranes that cover the brain and spinal cord). They can also result from the spread of cancer cells from other parts of the body, known as metastatic brain tumors.
Symptoms of brain neoplasms may vary depending on their size, location, and growth rate. Common symptoms include headaches, seizures, weakness or paralysis in the limbs, difficulty with balance and coordination, changes in speech or vision, confusion, memory loss, and changes in behavior or personality.
Treatment for brain neoplasms depends on several factors, including the type, size, location, and grade of the tumor, as well as the patient's age and overall health. Treatment options may include surgery, radiation therapy, chemotherapy, targeted therapy, or a combination of these approaches. Regular follow-up care is essential to monitor for recurrence and manage any long-term effects of treatment.
Neurocytoma
Central neurocytoma
Diffuse leptomeningeal glioneuronal tumor
TMEM81
List of MeSH codes (C04)
WHO classification of tumours of the central nervous system
Choroid plexus papilloma
List of MeSH codes (C10)
International Classification of Diseases for Oncology
Brain tumor
Oligodendroglioma
Palisade (pathology)
Neurocytoma - Wikipedia
Central Neurocytoma Imaging: Practice Essentials, Computed Tomography, Magnetic Resonance Imaging
A neurocytoma and an associated lenticulostriate artery aneurysm presenting with intraventricular hemorrhage: case report
Olfactory neurocytoma as a unique cause of chronic SIADH | BMJ Case Reports
Extraventricular neurocytoma - Global Genes
Central Neurocytoma Archives - Aunty M Brain Tumours
Central Neurocytoma Imaging: Overview, Computed Tomography, Magnetic Resonance Imaging
Neurocytoma arising from a mature ovary teratoma: a case report | Diagnostic Pathology | Full Text
Neuronal and mixed neuronal-glial - Brain Tumour Research
Rate of shunting and outcome after 2 years following excision of ventricular central neurocytoma Soliman WS - Egypt J Neurol...
Brain Tumors | Boston Children's Hospital
SJ901: Phase 1/2 Study of Mirdametinib for Low-Grade Glioma - St. Jude Children's Research Hospital
Cytologic Features of Central Neurocytomas of the Brain | Acta Cytologica | Karger Publishers
neuropathology blog: November 2018
Volume 4 Issue 1 - Dr. Julian Kenyon | CANCERactive
Brain Cancer Staging: Grading of Central Nervous System Tumors
94767002 - Neoplasm of uncertain behavior of brain - SNOMED CT
Choroid plexus papilloma | Radiology Reference Article | Radiopaedia.org
Buchbeschreibung: Robert Kraft : Spannungsabhängige Ionenkanäle in humanen Hirntumorzellen
David Raleigh | UCSF Profiles
Writer looking for participants to share stories - HER2 Support Group Forums
JPMA - Journal Of Pakistan Medical Association
Htt Mouse Gene Details | huntingtin | International Mouse Phenotyping Consortium
ALL CASES Archives - Page 4 of 4 - PULSE MD
Lipomatous glioneurocytoma of the posterior fossa with divergent differentiation: Case report<...
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Tumor12
- Neurocytoma is a type of nervous system benign tumor which is primarily derived from nervous tissue. (wikipedia.org)
- First described in 1982 by Hassoun et al, central neurocytoma (CN) is a rare tumor of neuroglial origin. (medscape.com)
- According to the World Health Organization classification, central neurocytoma is a benign grade II tumor with a good prognosis. (medscape.com)
- We present the first reported case of a central neurocytoma in a patient with intraventricular hemorrhage caused by rupture of an aneurysm on a lenticulostriate artery that supplied the tumor. (nih.gov)
- Pathological review demonstrated that the tumor was a neurocytoma. (nih.gov)
- Previous reports have demonstrated that intraventricular neurocytoma may present with tumor hemorrhage. (nih.gov)
- Central neurocytoma/extraventricular neurocytoma is a central nervous system (CNS) tumor composed of uniform round cells with neuronal differentiation. (biomedcentral.com)
- Central neurocytoma/extraventricular neurocytoma is a low-grade tumor with neuronal differentiation that occurs in the central nervous system (CNS), and histologically corresponds to WHO grade II. (biomedcentral.com)
- Background Central neurocytoma (CN) is an intraventricular tumor that affects young adults. (eg.net)
- Voltage-gated Na+-channels were also found in cells of a neurocytoma, a dysembryoblastic neuroepithelial tumor (DNT) and a medulloblastoma. (logos-verlag.de)
- Slow growing tumor cells - astrocytoma cells during serum deprivation and neuronal tumor cells of the neurocytoma and the DNT - showed the highest density of Na+-currents. (logos-verlag.de)
- The six cases comprised one rhabdoid tumor of the kidney, one ependymoma, two medulloblastomas, one neuroblastoma, and a type II neurocytoma of the spine. (metronomics.org)
Extraventricular neurocytoma4
- Extraventricular neurocytoma (EVN) a variant of central neurocytoma (see this term) is a rare neuronal neoplasm composed of round cells with neuronal differentiation which is located outside of the ventricular system usually within the spinal cord or cerebral hemispheres and that manifests with headache nausea vomiting complex partial seizures or focal neurological deficits. (globalgenes.org)
- Newly diagnosed with Extraventricular neurocytoma? (globalgenes.org)
- The typical lesions of central neurocytoma/extraventricular neurocytoma are at the interventricular foramen of the lateral ventricles (central neurocytoma) or brain parenchyma (extraventricular neurocytoma). (biomedcentral.com)
- Central neurocytoma usually occurs at the lateral ventricles, while extraventricular neurocytoma could occur at any extraventricular regions in the CNS. (biomedcentral.com)
Differentiation1
- Histologically, a central neurocytoma is characterized by a small, uniform neoplastic cell population with features of neuronal differentiation. (medscape.com)
Benign1
- Central neurocytoma is histologically benign and has an excellent prognosis. (medscape.com)
Resection1
- Organic bipolar disorder secondary to central neurocytoma resection: a case report. (bvsalud.org)
Lateral ventricles1
- Central neurocytoma is typically located in the lateral ventricles, near the foramen of Monro, with a characteristic attachment to the septum pellucidum. (medscape.com)
Case report1
- This is the fourth case report of neurocytoma outside the CNS to date. (biomedcentral.com)
Rare1
- Central neurocytoma is a rare tumour. (canceractive.com)
Cells1
- Studies have shown that neurocytoma cells exhibit both neural and glial phenotypes and have the properties reminiscent of precursor cells derived from the periventricular matrix. (medscape.com)
Woman1
- Based on these findings, the woman was diagnosed with neurocytoma arising from mature ovary teratoma, with microscopic foci of immature cartilage tissues. (biomedcentral.com)
Association1
- Hemorrhage associated with central neurocytoma has been described previously, but never in association with an aneurysm originating from a feeding artery. (nih.gov)
Atypical3
- Case Description: We describe a patient with a vasopressin-secreting atypical neurocytoma of the sellar and cavernous sinus region. (providence.org)
- 7. Tetraventricular Atypical Central Neurocytoma. (nih.gov)
- Differential diagnoses: arachnoid cyst, atypical choroid plexus papilloma, central neurocytoma or oligodendroglioma. (appliedradiology.com)
Intraventricular3
- 4. Intraventricular neurocytoma: case report. (nih.gov)
- 17. Central neurocytoma presenting with intraventricular hemorrhage: case report and review of literature. (nih.gov)
- Goergen SK, Gonzales MF, McLean CA (1992) Intraventricular neurocytoma: radiologic features and review of the literature. (springer.com)
Central21
- First described in 1982 by Hassoun et al, central neurocytoma (CN) is a rare tumor of neuroglial origin. (medscape.com)
- Central neurocytoma is typically located in the lateral ventricles, near the foramen of Monro, with a characteristic attachment to the septum pellucidum. (medscape.com)
- According to the World Health Organization classification, central neurocytoma is a benign grade II tumor with a good prognosis. (medscape.com)
- See the central neurocytoma images below. (medscape.com)
- Histologically, a central neurocytoma is characterized by a small, uniform neoplastic cell population with features of neuronal differentiation. (medscape.com)
- Like pineoblastoma, central neurocytoma also expresses synaptophysin but is usually negative for neurofilament, demonstrates a low mitotic rate, and is comprised of monomorphic tumor cells, often with an oligodendroglial appearance. (cap.org)
- 1. Giant central neurocytoma with tetraventricular and extra-axial extension. (nih.gov)
- 2. Central neurocytoma. (nih.gov)
- 3. Central neurocytoma: 2 case reports and review of the literature. (nih.gov)
- 5. Central neurocytoma: a clinico-pathological study of five cases. (nih.gov)
- 8. Central neurocytoma presenting with intratumoral hemorrhage. (nih.gov)
- 9. Central neurocytoma in third and fourth ventricles with aqueductal involvement. (nih.gov)
- 10. Central neurocytoma presenting with intratumoral hemorrhage 15 years after initial treatment by partial removal and irradiation. (nih.gov)
- 12. Central neurocytoma with lipofuscin granules--case report. (nih.gov)
- 14. Central neurocytoma with clinically malignant behavior. (nih.gov)
- 15. [Central neurocytoma: case report]. (nih.gov)
- 18. Central neurocytoma: two case reports and review of the literature. (nih.gov)
- Gracie was diagnosed with Central Neurocytoma. (community-news.com)
- I am a 27 year old woman, who had a central neurocytoma removed in July of 2000. (cancer.org)
- A variant of central neurocytoma, a rare neuronal neoplasm, composed of round cells with neuronal differentiation, which is located outside of the ventricular system, usually within the spinal cord or cerebral hemispheres and that manifests with headache, nausea, vomiting, complex partial seizures or focal neurological deficits. (cdc.gov)
- Organic bipolar disorder secondary to central neurocytoma resection: a case report. (bvsalud.org)
Neuroblastoma1
- Neurocytoma or neuroblastoma, a kind of tumor not generally recognized. (nih.gov)
Glioma1
- Other Malignant Tumors 79 (1) Myeloma 79 (2) Endothelioma 81 (3) Glioma 82 (4) Neurocytoma 84 (5) Hypernephroma 84 (6) Adamantinoma 85 (7) Chorioma 87 (8) Mixed Tumors 88 (9) Teratoma 90 VII. (nih.gov)
Fourth1
- 16. Fourth ventricular neurocytoma: case report and review of the literature. (nih.gov)