Parotid Gland
Parotid neoplasms: a report of 250 cases and review of the literature. (1/312)
A 25-year experience with parotid tumors was reviewed. From a total of 250 neoplasms, 173 were histologically benign and 77 were malignant. Benign mixed tumors accounted for 59% of all lesions. Clinical parameters used to diagnose parotid neoplasms were found to be unreliable in determining whether a given tumor was benign or malignant. The mean age for malignant lesions was 10 years greater than for benign lesions. The phenomenon of malignant transformation of a benign tumor was considered in four patients. Complete surgical excision is the safest and preferred method for diagnosis. Preoperative needle or incisional biopsy are associated with a high degree of local recurrence. The appropriate management of any parotid tumor is predicated on special histological type. Local excision or enucleation no longer have a place in the surgical management of benign parotid tumors. Postoperative tumor recurrence and morbidity are directly related to awareness of surgical anatomy and pursuit of correct surgical techniques for adequate resection. The five-year recurrence rate for 102 benign mixed tumors was 6%. Recurrence in malignant tumors varied with specific histological types but was generally high. Five-year survival for all malignant parotid tumors was 48%. (+info)Clinico-pathological and treatment-related factors influencing survival in parotid cancer. (2/312)
One hundred and three patients with primary parotid cancer treated surgically at the Christie Hospital, Manchester (1952-1992), were analysed to assess the influence on survival of prognostic and treatment-related factors. Thirty-seven patients were treated by surgery alone (SG), 66 received post-operative radiation (SG+RT). Median follow-up was 12 years, minimum 5 years. The 10-year disease-specific survival rates for stage I, II and III/IV were 96%, 61% and 17% respectively (P < 0.0001). The various histological types segregated into three survival patterns: low-, intermediate-and high-grade with 10-year survival rates of 93%, 41% and 50% respectively (P < 0.0001). On multivariate analysis, the factors influencing risk of cancer death in order of importance were: tumour size > 4 cm (P < 0.001), presence of nodes (P = 0.001), histology of adenoid cystic carcinoma (P = 0.01), high-tumour grade (P = 0.02) and perineural involvement (P = 0.01). Neither the extent of surgery nor the operator influenced outcome. Overall, adjuvant RT significantly reduced locoregional recurrence (SG+RT 15% vs SG 43%; P = 0.002) but not survival, although on subanalysis, there was a trend to improved survival with large cancers and high-grade tumours. Long-term survival is determined primarily by tumour characteristics, namely clinical stage and grade. Post-operative RT contributes significantly to locoregional control and probably confers some survival advantage in high-risk patients. (+info)Simultaneous phenotypically distinct but clonally identical mucosa-associated lymphoid tissue and follicular lymphoma in a patient with Sjogren's syndrome. (3/312)
A 44-year-old woman with a 12-year history of Sjogren's syndrome (SS) developed a low-grade mucosa-associated lymphoid tissue (MALT) lymphoma in the parotid gland. Two years later, she presented with generalized lymphadenopathy and hepatosplenomegaly and a follicular lymphoma was diagnosed. To investigate the relationship of the two histologically distinct lymphomas, we re-examined their histology and immunophenotype and studied the lymphomatous tissue from the parotid, cervical lymph node, and spleen using molecular genetic methods. Histologic and immunophenotypic studies confirmed the previous diagnoses and also identified a previously unnoticed focus of follicular lymphoma in the second parotid gland biopsy. Polymerase chain reaction (PCR) amplification of the rearranged Ig heavy-chain gene showed the same sized dominant product in the MALT lymphoma and the follicular lymphoma. Similarly, PCR analysis of the t(14:18) translocation yielded an identical sized band from both MALT and follicular lymphoma. Cloning and sequencing of the Ig PCR products showed an identical CDR3 sequence from each lesion, indicating a common clonal lineage. The follicular lymphoma of the parotid gland lymph node and the follicular lymphoma of the spleen showed an identical mutation signature to that of the salivary gland MALT lymphoma. We propose that follicular lymphoma in the parotid gland lymph node may have resulted from colonization of lymphoid follicles by MALT lymphoma cells, following which the tumor cells were induced to express a follicular lymphoma phenotype, due to Bcl-2 overexpression caused by t(14;18), leading to a change in clinical behavior resulting in rapid widespread dissemination of disease. These observations suggest that the distinct phenotypes of low-grade B-cell lymphomas may be the consequence of interplay between genetic and local microenvironmental factors. (+info)Perioperative frozen section examination in parotid gland tumors. (4/312)
CONTEXT: The minimal recommended surgical approach to parotid tumors is partial parotidectomy with resection of the superficial lobe of the gland. Histologic diagnosis prior to surgery is not possible, as incisional biopsies are contraindicated due to the possibility of facial nerve injury or incomplete tumor resection. Thus, the biopsies tend to be perioperative. OBJECTIVE: To compare the results of frozen section examination with the definitive pathological diagnosis. DESIGN: Accuracy study by retrospective analysis. SETTING: Head and Neck Surgery Service of Heliopolis Hospital, Sao Paulo, Brazil. SAMPLE: 153 cases of parotid gland tumors treated between 1977 and 1994. DIAGNOSTIC TEST: Frozen section and pathological diagnosis. MAIN MEASUREMENTS: Sensibility and specificity of the frozen section examination. RESULTS: Frozen section study diagnosed 19 (12.4%) malignant and 127 (83.7%) benign tumors. Sensitivity of the frozen sections for malignancy was 61.5% (95% CI 54 to 69%) and specificity was 98% (95% CI 94 to 100%), and this result is comparable to the literature. CONCLUSIONS: We consider that frozen section examination for salivary gland tumors is not sufficient on its own for deciding on the best management. Their interpretation must be correlated with clinical and intraoperative findings, in association with the surgeon's experience. (+info)Follicle center lymphoma and Warthin tumor involving the same anatomic site. Report of two cases and review of the literature. (5/312)
We report 2 cases of follicle center non-Hodgkin lymphoma (NHL) and Warthin tumor involving the same site. Case 1 is a 68-year-old woman with Warthin tumor and grade 1 follicular NHL involving a periparotid lymph node. She had localized NHL and was treated with radiation therapy; dissemination developed 54 months later. Case 2 is a 55-year-old man with a 17-year history of a parotid mass with gradual enlargement during the last 5 years. Surgical excision revealed Warthin tumor and grade 1 follicular NHL involving the right parotid gland and surrounding lymph nodes. Immunohistochemical studies supported the diagnosis of NHL in both cases; the neoplasms were positive for CD20 and BCL-2 and negative for CD3. Polymerase chain reaction analysis done on paraffinembedded tissue of case 1 revealed monoclonal immunoglobulin heavy chain gene rearrangement and bcl-2/JH fusion DNA sequences diagnostic of the t(14;18)(q32;q21). The small size of the Warthin tumor in case 1, clearly arising in lymph node, supports the hypothesis that Warthin tumor arises from heterotopic salivary gland ducts within lymph nodes. The localized NHL in both patients suggests that the NHL initially arose in the lymph node involved by Warthin tumor, and, thus, the Warthin tumor may have provided a source of long-term antigenic stimulation from which a monoclonal B-cell population subsequently arose. (+info)Clinically benign parotid tumours: local dissection as an alternative to superficial parotidectomy in selected cases. (6/312)
In a personal series of 162 tumours, 101 were pleomorphic adenomas 28 of which were removed by elective local extra capsular dissection and 73 by a conventional nerve dissection. There were no recurrences in either group after a mean follow-up 10.3 years, range 3-21 years for local dissection and 8.3 years, range 3-22 years for nerve dissection. Frey's syndrome did not occur after local dissection but was present in 25% of patients after a nerve dissection. Of the 162 parotid lumps, 17 proved to be a carcinoma but only one was deemed suitable for a local removal, a low grade muco epidermoid carcinoma of the accessory lobe and no recurrence has occurred after 8 years. In benign disease, local dissection gives similar results to conventional nerve dissection with less morbidity and confirms that tumour recurrence cannot be ascribed to any properties of the tumour but lies in the hands of the surgeon and depends on the care with which the tumour is removed. (+info)The place of magnetic resonance and ultrasonographic examinations of the parotid gland in the diagnosis and follow-up of primary Sjogren's syndrome. (7/312)
OBJECTIVE: The aim was to determine the place of magnetic resonance imaging (MRI) and ultrasonographic (US) examination in the diagnosis and follow-up of Sjogren's syndrome (SS). METHODS: Parotid MRI and US examinations were carried out on 44 primary SS patients and 52 controls of similar age. RESULTS: The most important structural changes in SS were different degrees of parenchymal inhomogeneity, which could be detected by both methods, and were found more frequently in the SS patients than in the controls (MRI: 95.4 vs 17. 3%; US: 88.6 vs 7.7%; P<0.001). There was good agreement between the MRI and US findings both in the SS cases (93.2%) and in the controls (86.5%). In one SS patient who developed parotid lymphoma, the US examination showed a hypoechoic 'cobblestones'-like inhomogeneous internal pattern which was coupled with an almost homogeneous MRI pattern. CONCLUSIONS: MRI appears unnecessary as a routine method in the diagnosis of SS; US examination is suitable both for the diagnosis and follow-up of SS. The above combination of the seemingly contradictory US and MRI findings is highly characteristic of lymphoma which has developed in the course of the disease. (+info)Hemangioendothelioma of the parotid gland in infants: sonography and correlative MR imaging. (8/312)
BACKGROUND AND PURPOSE: Hemangioendothelioma is the most common parotid gland tumor of childhood, and is diagnosed on clinical grounds, supported by imaging findings. Previous work has suggested that MR is the best imaging technique for assessment of parotid hemangioendothelioma. Demonstration of a reliable sonographic appearance would reduce the need for MR imaging in infants with this lesion. METHODS: We performed high-frequency sonography (including color Doppler and power Doppler imaging) in three patients, each with a diagnosis of parotid hemangioendothelioma confirmed by clinical follow-up. Two patients were also examined with MR imaging and labeled red cell scintigraphy. RESULTS: All sonographic studies showed a homogeneous mass enlarging and replacing most or all of the visualized parotid gland, with a lobular internal structure, fine echogenic internal septations, and a mildly lobulated contour. Color Doppler and power Doppler imaging showed extremely high vascularity within the mass. Correlative MR images in two infants showed a well-defined lesion with uniform intense contrast enhancement. Labeled red cell scintigraphy showed a well-defined area of intense activity. CONCLUSION: In the presence of a typical clinical history, sonography and clinical follow-up alone may prove to be sufficient for safe management of parotid hemangioendothelioma. MR imaging or labeled red cell scintigraphy may only be required if the sonographic features are atypical. These findings require confirmation in a larger series of patients. (+info)Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).
Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.
Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.
The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.
The parotid gland is the largest of the major salivary glands. It is a bilobed, accessory digestive organ that secretes serous saliva into the mouth via the parotid duct (Stensen's duct), located near the upper second molar tooth. The parotid gland is primarily responsible for moistening and lubricating food to aid in swallowing and digestion.
Anatomically, the parotid gland is located in the preauricular region, extending from the zygomatic arch superiorly to the angle of the mandible inferiorly, and from the masseter muscle anteriorly to the sternocleidomastoid muscle posteriorly. It is enclosed within a fascial capsule and has a rich blood supply from the external carotid artery and a complex innervation pattern involving both parasympathetic and sympathetic fibers.
Parotid gland disorders can include salivary gland stones (sialolithiasis), infections, inflammatory conditions, benign or malignant tumors, and autoimmune diseases such as Sjögren's syndrome.
Parotid diseases refer to conditions that affect the parotid glands, which are the largest of the salivary glands and are located in front of each ear. These glands produce saliva that helps in digestion and keeps the mouth moist. Parotid diseases can cause swelling, pain, dry mouth, or difficulty swallowing, among other symptoms. Some common parotid diseases include:
1. Parotid gland infection (also called parotitis) - an inflammation of the parotid gland due to bacterial or viral infections.
2. Salivary gland stones (also called sialolithiasis) - calcified deposits that form in the salivary ducts and can block the flow of saliva.
3. Salivary gland tumors - abnormal growths that can be benign or malignant, and may require surgical removal.
4. Parotid gland inflammation (also called sialadenitis) - an inflammation of the parotid gland due to autoimmune disorders, radiation therapy, or dehydration.
5. Parotid gland cysts (also called ranula or mucocele) - fluid-filled sacs that form in the salivary gland or duct.
Proper diagnosis and treatment of parotid diseases require a thorough evaluation by a healthcare professional, often involving imaging studies, laboratory tests, and biopsies.
Parotid gland
Sarah Stewart (cancer researcher)
Salivary gland disease
Sebaceous lymphadenoma
Parotidectomy
Warthin's tumor
Smile surgery
Masseter muscle
Facial nerve paralysis
Salivary gland tumour
Facial nerve decompression
Sialadenitis
Pleomorphic adenoma
Facial muscles
Oncocytoma
Basal cell adenoma
Salivary gland-like carcinoma of the lung
Sialoblastoma
C7
Ectopic salivary gland tissue
Secretory carcinoma
Oral medicine
Saliva testing
Carcinosarcoma
Carcinoma ex pleomorphic adenoma
Polymorphous low-grade adenocarcinoma
Odontogenic cyst
Epithelial-myoepithelial carcinoma
Chronic sclerosing sialadenitis
Sclerosing polycystic adenosis
Parotid gland - Wikipedia
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Tumors30
- Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
- Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
- [ 4 , 5 ] ) Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
- Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
- in 1953, he reported parotid tumors in these mice. (cdc.gov)
- So in 1956, when Stewart approached Eddy for assistance growing the agent causing parotid tumors in mice, Eddy readily agreed and the 2 women rapidly worked out the characteristics of the agent that was not referred to as a virus in their publications until 1959. (cdc.gov)
- The purpose of this study was to document the delayed CT enhancement characteristics of parotid pleomorphic adenomas and to preliminarily compare these results with the enhancement characteristics of other parotid gland tumors. (ajnr.org)
- This feature may be useful in selecting an appropriate contrast delay when scanning possible pleomorphic adenomas to improve lesion conspicuity and, potentially, to better distinguish these tumors from other parotid abnormalities. (ajnr.org)
- Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
- Rare: 2.3% of benign salivary tumors 6 th decade M:F = 1:1 Parotid: 78% Submandibular gland: 9% Minor salivary glands: palate, buccal mucosa, tongue. (slideserve.com)
- This theory more logically explains neoplasms that contain multiple discrete cell types, such as pleomorphic adenomas and Warthin tumors. (medscape.com)
- Epithelial tumors of the parotid gland comprise 3% of head and neck tumors, and 70%-80% of those are benign. (tau.ac.il)
- Purpose: To assess the usefulness of amide proton transfer (APT) imaging in differentiating parotid tumors. (elsevierpure.com)
- Material and methods: We retrospectively analyzed 43 histopathologically proven parotid solid tumors with diameters ≥2 cm. (elsevierpure.com)
- Conclusion: The mean APT SI of the malignant parotid tumors was significantly higher than that of the benign parotid tumors. (elsevierpure.com)
- Most of the tumors that develop this way are seen in parotid gland. (entcase.org)
- While WT is described as the most common neoplasm among synchronous parotid gland tumors, WT in conjunction with PA is described as the most frequent synchronous parotid tumor combination [7]. (entcase.org)
- Oct 19, 2022 Warthin tumors are the 2 nd most common benign parotid tumor (after pleomorphic adenoma) and represent up to 10 of all parotid tumors. (stubensaenger.de)
- Parotid gland tumors are very common and often benign. (drsaeedi.com)
- Adults and children are likely to be at risk of having parotid gland tumors. (drsaeedi.com)
- Salivary glands (especially the parotid glands) can be infected by viruses and tumors. (drsaeedi.com)
- For many people with parotid gland tumors, parotidectomy is necessary. (quick-advices.com)
- Recurrent parotid tumors unfortunately regrow after initial treatment, requiring further surgery. (quick-advices.com)
- For many people with parotid gland tumors, surgery performed by a head and neck surgeon is the main treatment. (quick-advices.com)
- What type of tumors can develop in the parotid gland? (quick-advices.com)
- Parotid tumors are abnormal growths of tissue in the parotid gland, which is the largest of the three pairs of salivary glands. (quick-advices.com)
- Parotid tumors that spread to the lymph nodes may require the lymph nodes to be removed. (quick-advices.com)
- 80% of neoplasms are benign, although their tendency to recur or develop into malignant tumors varies. (medtigo.com)
- With a male-to-female ratio of 1:2 overall and 1:3 for benign tumors, salivary gland neoplasms more frequently affect women. (medtigo.com)
- The equitable distribution of benign and malignant neoplasms makes up 10 to 15% of all salivary gland tumors in the submandibular gland. (medtigo.com)
Recurrence4
- Those located in the minor salivary glands had a lower recurrence risk than did pleomorphic adenomas in the parotid glands. (medscape.com)
- To analyze the patterns of local-regional recurrence in patients with head and neck cancer treated with parotid-sparing conformal and segmental intensity-modulated radiotherapy (IMRT). (nih.gov)
- BCA carries a favorable prognosis in comparison with other salivary gland neoplasms, especially since recurrence is not common. (e-acfs.org)
- According to this algorithm, 118 parotid gland surgeries were performed without recurrence except in one case. (stubensaenger.de)
Tumor18
- The most common tumor of the parotid gland is the pleomorphic adenoma , which represents about 60% of all parotid neoplasms, as seen in the table below. (medscape.com)
- The tumor was confirmed as a high-grade EOS in the parotid gland. (researchsquare.com)
- During the operation, the size of the tumor was about 4 × 3cm, which base involved the left parotid gland and masseter area. (researchsquare.com)
- Site of the primary tumor was the parotid (7), sublingual (2), and submandibular (1) glands. (icr.ac.uk)
- Journal of Neoplasms focuses on both experimental and clinical studies related to neoplasms, such as cancer and tumor biology, carcinogenesis, and metastasis. (openaccesspub.org)
- Pleomorphic adenoma is the most common tumor of the parotid gland. (tau.ac.il)
- Sebaceous lymphadenoma is a benign rare tumor of the salivary glands, with reported cases accounting for less than 0.2% of all salivary gland neoplasms. (remedypublications.com)
- In this study, the diagnosis and treatment process of a patient with an unrelated synchronous warthin tumor and basal cell adenoma combination in the ipsilateral parotid gland was described. (entcase.org)
- Warthin tumor (WT) is predominantly seen in parotid gland. (entcase.org)
- You may need this surgery if a tumor forms in your parotid gland. (stubensaenger.de)
- Initially described in 1929, Warthin's tumor is a benign neoplasm predominantly found in the parotid gland of the salivary glands. (stubensaenger.de)
- Parotidectomy surgery is a resection of the parotid glands due to the existence of a tumor within. (drsaeedi.com)
- It is called superficial because the surgeon resects only the exterior part of the gland for parotid tumor removal. (drsaeedi.com)
- The facial nerve and the surrounding tissues are also removed with the parotid gland if they are affected by the tumor, which will affect or change the facial motions. (drsaeedi.com)
- In some cases, the facial nerve may be temporarily or, very rarely, permanently weakened due to removal of a parotid gland tumor. (quick-advices.com)
- The risk of facial nerve weakness is directly related to the size, extent, and type of parotid gland tumor. (quick-advices.com)
- A pathologist looks at the aspiration sample from a parotid tumor under a microscope to determine if there is cancer present. (quick-advices.com)
- This patient has a large right-sided parotid salivary gland tumor. (msdmanuals.com)
Glands21
- In humans, the two parotid glands are present on either side of the mouth and in front of both ears. (wikipedia.org)
- Sometimes accessory parotid glands are found close to the main parotid glands. (wikipedia.org)
- The parotid glands are a pair of mainly serous salivary glands located below and in front of each ear canal, draining their secretions into the vestibule of the mouth through the parotid duct. (wikipedia.org)
- From lateral to medial, these are: Facial nerve Retromandibular vein External carotid artery Superficial temporal artery Branches of the great auricular nerve Maxillary artery Sometimes accessory parotid glands are found as an anatomic variation. (wikipedia.org)
- Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
- The major salivary glands consist of the following 3 pairs of glands: the parotid glands, the submandibular glands, and the sublingual glands. (medscape.com)
- Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
- Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
- Acinic cell carcinoma (ACC) makes up about 6.5% of all salivary gland neoplasms and roughly 18% of all malignant neoplasms of the salivary glands . (webpathology.com)
- Materials and method: Stimulated parotid saliva was collected simultaneously from both glands in 50 healthy volunteers whose MPH use was on a dominant side of the head. (huji.ac.il)
- Conclusions: Parotid glands adjacent to handheld MPH in use respond by elevated salivary rates and decreased protein secretion reflecting the continuous insult to the glands. (huji.ac.il)
- The parotid glands are one pair of the salivary glands. (drsaeedi.com)
- Parotid is the largest main pair out of three paired salivary glands. (drsaeedi.com)
- Parotid glands are situated on each side of the face below and in the front of the ear. (drsaeedi.com)
- Parotid glands excrete saliva, which eases chewing and ingestion. (drsaeedi.com)
- After that, the surgeon either partially removes the superficial part of the parotid glands or eradicates the parotid glands completely. (drsaeedi.com)
- A parotidectomy is the surgical excision (removal) of the parotid gland, the major and largest of the salivary glands. (quick-advices.com)
- There are two parotid glands, one on each side of the face. (quick-advices.com)
- Salivary gland neoplasms are abnormal cells growing in the salivary gland or in the ducts that drain the glands. (medtigo.com)
- They can be present in different locations and have different histologies, including the sublingual, parotid, minor salivary glands and submandibular. (medtigo.com)
- They often present as painless enlarging masses, mostly located in parotid glands and mostly benign. (surgeryscience.com)
Left parotid gland3
- A 60 years old female tobacco smoker patient presented to our institution with a slowly enlarging, painless mass for three years in left parotid gland. (entcase.org)
- Ultrasonography of the left neck demonstrated two cystic spheric lesions of 13 mm and 8 mm in diameter at left parotid gland. (entcase.org)
- Computed tomography (CT) revealed a homogeneous and well-enhanced 1.5-cm sized nodule in the tail of the left parotid gland ( Fig. 1 , left). (e-acfs.org)
Growths of tissue2
- Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
- Neoplasms are abnormal, uncontrolled growths of tissue that have the potential to spread and cause serious health issues. (openaccesspub.org)
Pleomorphic adenomas3
- Parotid pleomorphic adenomas: delayed CT enhancement. (ajnr.org)
- BACKGROUND AND PURPOSE Weak or absent CT enhancement in pleomorphic adenomas of the parotid gland has been observed immediately after i.v. contrast administration. (ajnr.org)
- CONCLUSION Delayed CT contrast enhancement is observed in parotid pleomorphic adenomas, increasing in both degree and homogeneity with time. (ajnr.org)
Affecting the parotid gland1
- We herein describe 3 new cases (all affecting the parotid gland) in 2 women (39- and 55-y old) and 1 man (35-y old). (icr.ac.uk)
Deep lobe6
- We describe an unusual case of sebaceous lymphadenoma in a patient with previous breast cancer, identified as an incidental finding of a parotid deep lobe lesion on computerized tomography, and treated with surgical excision. (remedypublications.com)
- In addition, magnetic resonance (MR) of the neck revealed two lesions, measured 8.5x8.8 mm in superficial lobe of the parotid gland and 13.3x10.2 mm in deep lobe of the gland which were well-circumscribed, hypodense in T1A series and slightly hyperdense in T2A series (Figure 1). (entcase.org)
- The superficial mass was diagnosed as salivary gland neoplasm in tubular pattern (though it is not the final diagnosis, BCA and low grade adenoid cystic carcinoma were considered as differential diagnosis) and the mass in the deep lobe was resulted with findings relevant to WT. (entcase.org)
- The patient underwent total parotidectomy because the mass involved the deep lobe of the parotid gland ( Fig. 2 ). (e-acfs.org)
- It means eradicating the parotid gland completely, including the deep lobe and the superficial lobe, while keeping the facial nerve intact. (drsaeedi.com)
- The parotid gland consists of two lobes: the superficial lobe and the deep lobe. (quick-advices.com)
Lobe2
- The stylomandibular ligament separates parotid gland from the superficial lobe of the submandibular gland. (wikipedia.org)
- Intraoperatively, the mass was found in the left parotid region, the pedicle was located in front of the left ear, and the base of the mass was located in the superficial lobe of the parotid gland and masseter muscle. (researchsquare.com)
Recurrent3
- It is a myoepithelial or epithelial neoplasm that arises from pleomorphic adenoma, whether primary or recurrent. (org.pk)
- We present a case of a 35 years old male with recurrent Dermatofibrosarcoma Protuberans of right parotid gland. (aku.edu)
- Higher disease activity, recurrent parotid gland swelling, presence of cryoglobulins, and hypocomplementemia at baseline indicate a higher likelihood of developing lymphoma. (medscape.com)
Submandibular gland2
Carcinoma3
- Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. (nih.gov)
- Carcinoma ex pleomorphic adenoma is a neoplasm of the salivary gland that causes 3.6% of salivary gland tumours and 12% of salivary gland malignancies. (org.pk)
- The report is of a 45-year-old female patient with a history of high blood pressure and multiple surgeries for cancer, including thyroid cancer, parotid carcinoma, breast cancer, and endometrial cancer. (bvsalud.org)
20211
- Jan 21, 2021 Parotid neoplasms account for 80 of salivary neoplasms. (stubensaenger.de)
Uninvolved parotid gland1
- The mean normalized Hounsfield unit (HU) attenuation of each lesion was computed by drawing a region of interest around the entire mass and dividing the resulting HU value by that of the contralateral uninvolved parotid gland. (ajnr.org)
Second most common benign1
- Warthin tumour is the second most common benign neoplasm of the parotid gland. (stubensaenger.de)
Saliva5
- Each parotid is wrapped around the mandibular ramus, and secretes serous saliva through the parotid duct into the mouth, to facilitate mastication and swallowing and to begin the digestion of starches. (wikipedia.org)
- Objective: To evaluate whether MPH induces physiologic changes in the adjacent parotid gland, located on the dominant side, in terms of secretion rates and protein levels in the secreted saliva. (huji.ac.il)
- CA130 was determined in parotid saliva from 8 rats fed different diets, with or without autonomic denervation. (umn.edu)
- CA130 could be determined in parotid saliva of rats, irrespective of diet and/or autonomic denervation. (umn.edu)
- The parotid gland is a salivary gland, responsible for making saliva. (quick-advices.com)
Neck4
- Fifty-eight patients with head and neck cancer were treated with bilateral neck radiation (RT) using conformal or segmental IMRT techniques, while sparing a substantial portion of one parotid gland. (nih.gov)
- Planning goals included coverage of all PTVs (with a minimum of 95% of the prescribed dose) and sparing of a substantial portion of the parotid gland in the side of the neck at less risk. (nih.gov)
- In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men. (nih.gov)
- SGT's are more common in women than in men which represents 2%-3% of head and neck neoplasms. (surgeryscience.com)
Adenoma3
- Literature suggests about 6.2% of pleomorphic adenoma harbour malignancy, 2 and most of these cases involve the parotid gland. (org.pk)
- Pleomorphic adenoma of parotid gland, is a relatively common injury, with prevalence of approximately 70% of confirmed cases. (bvsalud.org)
- Pleomorphic adenoma is the most common intraoral benign neoplasm. (msdmanuals.com)
Superficial3
- The parotid duct, a long excretory duct, emerges from the front of each gland, superficial to the masseter muscle. (wikipedia.org)
- Arterial supply The external carotid artery and its terminal branches within the gland, namely, the superficial temporal and the maxillary artery, also the posterior auricular artery supply the parotid gland. (wikipedia.org)
- What is the experience in using a superficial muscoloaponeurotic system (SMAS)-platysma flap in facial-aesthetic parotid surgery for benign parotid neoplasms? (enttoday.org)
Lesion2
Epidemiology1
- JN is pleased to publish research that covers topics related to neoplasms, ranging from epidemiology to pathology, carcinogenesis, etiopathogenesis, and clinical management. (openaccesspub.org)
Etiology3
- The etiology of salivary gland neoplasms is not fully understood. (medscape.com)
- Recent evidence suggests that the bicellular stem cell theory is the more probable etiology of salivary gland neoplasms. (medscape.com)
- While the vast majority of soft tissue lesions in the oral cavity represent infectious, traumatic, or reactive processes rather than neoplasms, the precise etiology can often be determined through a careful history and clinical examination. (medscape.com)
Pathology1
- Parotid gland is salivary gland most affected by pathology. (bvsalud.org)
Tissue3
- The parotid papilla is a small elevation of tissue that marks the opening of the parotid duct on the inner surface of the cheek. (wikipedia.org)
- Extraskeletal osteosarcoma (EOS) is a rare malignant soft tissue neoplasm. (researchsquare.com)
- Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)
Prognosis1
- It also covers advances in immunotherapy, genetics, and genomics of neoplasms, novel biomarkers, and advances in imaging in neoplasm diagnosis and prognosis. (openaccesspub.org)
Major salivary1
- The parotid gland is a major salivary gland in many animals. (wikipedia.org)
Surgical1
- The diagnosis is usually confirmed with a fine needle aspiration biopsy, and surgical excision is the main treatment of this malignant neoplasm. (nih.gov)
Radiotherapy1
- We seek to provide comprehensive data, analyses, and evidence-based research including tumorigenesis and metastasis, immunology and immunotherapy, stem cell transplantation, radiotherapy and oncological drug therapy, artificial intelligence and big data in neoplasms, and much more. (openaccesspub.org)
Oncocytoma1
- We report on a case where strong PSA immunoreactivity of a parotid oncocytoma led to its confusion with metastatic prostate cancer. (johnshopkins.edu)
Gland located1
- Where is the parotid gland located? (drsaeedi.com)
Methods2
- METHODS Preoperative CT scans from 18 pathologically proved parotid gland neoplasms were reviewed retrospectively. (ajnr.org)
- Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. (lookformedical.com)
Primary3
- Notably, there are few reports on primary EOS in parotid gland and we report the highly malignant one. (researchsquare.com)
- Herein, we report one case of primary parotid EOS with pulmonary metastasis and discuss its clinical findings in view of the cases previously reported in the literature. (researchsquare.com)
- Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
Metastasis1
- Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
Lymph nodes1
- citation needed] Lymphatic drainage The gland is mainly drained into the preauricular or parotid lymph nodes which ultimately drain to the deep cervical chain. (wikipedia.org)