Sterol Esterase
Lipolysis
The metabolic process of breaking down LIPIDS to release FREE FATTY ACIDS, the major oxidative fuel for the body. Lipolysis may involve dietary lipids in the DIGESTIVE TRACT, circulating lipids in the BLOOD, and stored lipids in the ADIPOSE TISSUE or the LIVER. A number of enzymes are involved in such lipid hydrolysis, such as LIPASE and LIPOPROTEIN LIPASE from various tissues.
Cyclic AMP-Dependent Protein Kinases
IL-1 polymorphism and periimplantitis. A literature review. (1/24)
The most important factor leading to periimplantitis with bone loss appears to be an inflammatory process due to plaque accumulation. The object of this article was to present a review of the literature on a possible correlation between IL-1 polymorphism and periimplantitis. Research was carried out in the PUBMED and WEB OF KNOWLEDGE literature databases and 27 relevant articles were found. Of these articles, 4 groups of authors came to the conclusion that no correlation exists between IL-1 polymorphism and periimplantitis. In 5 articles by 4 groups of authors, the influence of IL-1 polymorphism on periimplantitis is unclear. 9 studies prove a correlation between IL-1 polymorphism and periimplantitis, and 6 studies also document a direct linkage between gene polymorphism and periimplantitis, if certain cofactors are present. IL-1 polymorphism is frequently connected with "noninfectious periimplant bone loss". Other studies prove that the inflammatory mediators and IL-1beta were significantly elevated in the gingival crevicular fluid (GCF) of infected implants. Many studies document that IL-1 polymorphism alone cannot be considered a risk factor for bone loss, but in combination with smoking, it is closely associated with periimplant bone loss. More studies are needed to discover possible correlations between IL-1 polymorphism and periimplantitis. (+info)Unusual presentation of active implant periapical lesions: a report of two cases. (2/24)
Active implant periapical lesion (IPL) is a rare lesion which has been reported as one of the causes of dental implant failures. Usually, an affected implant shows radiolucency in the apical area, while remaining clinically stable. IPL is often accompanied by symptoms of pain, swelling, tenderness, and fistulation. In this paper, we describe two cases of IPL with very unusual findings which led to implant failure. A large IPL associated with an inflammatory cyst in the anterior maxilla, and a mandibular IPL resulting in an extra-oral fistula are presented. The etiology and treatment approaches for IPL are discussed. (+info)Interleukins IL-6, IL-8, IL-10, IL-12 and periimplant disease. An update. (3/24)
INTRODUCTION: A study is made of the usefulness of cytokines (such as interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10) and interleukin-12 (IL-12)) as markers of periimplant disease (mucositis and periimplantitis). An increase in the levels of these cytokines in dental implant crevicular fluid may give rise to a lack of osteointegration, bone loss or implant failure. OBJECTIVE: To review the literature relating IL-6, IL-8, IL-10 and IL-12 levels to dental implant surgery and periimplantitis. MATERIAL AND METHOD: A PubMed literature search was made of articles in English and Spanish, using the key words "cytokine and dental implants", cytokine and periimplantitis", "IL-6, IL-8, IL-10, IL-12 and dental implants", "IL-6, IL-8, IL-10, IL-12 and periimplantitis". Fourteen articles were found and classified into two groups relating interleukin levels to: a) periimplant disease; and b) their influence upon dental implant osteointegration without periimplant disease. CONCLUSIONS: An increase in interleukin levels is observed in patients with periimplant disease, though there is controversy over the effect of interleukins in crevicular fluid and periimplantitis in relation to implant failure or the development of periimplant disease. (+info)Development of an animal model for Aggregatibacter actinomycetemcomitans biofilm-mediated oral osteolytic infection: a preliminary study. (4/24)
(+info)Electrochemical disinfection of dental implants--a proof of concept. (5/24)
(+info)Peri-implantitis: associated microbiota and treatment. (6/24)
INTRODUCTION: Peri-implantitis is a late complication of dental implant treatment, induced by microbiological changes. Since the disorder is frequent, a review is indicated of the microorganisms that influence it and of the existing treatment options. OBJECTIVE: To conduct a literature review of the microbiota associated to peri-implantitis and the existing treatment options. MATERIAL AND METHOD: A PubMed literature search was made of the studies on the microbiota associated to dental implants in healthy patients and patients with peri-implantitis, as well as of the latest treatment developments, using the following key words: "peri-implantitis AND microbiota", "periimplantitis AND microbiota", "peri-implantitis AND treatment", and "periimplantitis AND treatment". Only clinical studies in humans were considered. The following criteria were applied for including articles in the analysis: a) for the peri-implant microbiota, the search limits were human studies after the year 2000; and b) for the treatment of peri-implantitis, the search limits were randomized and controlled clinical trials (RCTs) in humans, with a minimum follow-up of 4 months, and publication after the year 2000. RESULTS: A total of 18 articles were selected in relation to peri-implant microbiota, and 13 in relation to the treatment of peri-implantitis (8 involving nonsurgical mechanical treatments and 5 surgical procedures). CONCLUSIONS: Evaluation of the literature has shown the microbiota associated to peri-implantitis to be more complex than that found under healthy peri-implant conditions - the main flora consisting of anaerobic gramnegative bacteria. No clear criteria have been identified for the diagnosis and treatment of peri-implantitis. (+info)Failures in implants. (7/24)
(+info)Pyrosequencing reveals unique microbial signatures associated with healthy and failing dental implants. (8/24)
(+info)Sterol esterase is an enzyme that catalyzes the hydrolysis of sterol esters into free sterols and fatty acids, playing a crucial role in intracellular lipid metabolism and homeostasis.
A sterol esterase is an enzyme that catalyzes the hydrolysis of sterol esters, which are fatty acid esters of sterols (such as cholesterol) that are commonly found in lipoproteins and cell membranes. Sterol esterases play a crucial role in the metabolism of lipids by breaking down sterol esters into free sterols and free fatty acids, which can then be used in various biochemical processes.
There are several types of sterol esterases that have been identified, including:
1. Cholesteryl esterase (CE): This enzyme is responsible for hydrolyzing cholesteryl esters in the intestine and liver. It plays a critical role in the absorption and metabolism of dietary cholesterol.
2. Hormone-sensitive lipase (HSL): This enzyme is involved in the hydrolysis of sterol esters in adipose tissue, as well as other lipids such as triacylglycerols. It is regulated by hormones such as insulin and catecholamines.
3. Carboxylesterase (CES): This enzyme is a broad-specificity esterase that can hydrolyze various types of esters, including sterol esters. It is found in many tissues throughout the body.
Sterol esterases are important targets for drug development, as inhibiting these enzymes can have therapeutic effects in a variety of diseases, such as obesity, diabetes, and cardiovascular disease.
Lipolysis is the process of breaking down stored triglycerides into glycerol and free fatty acids within lipid droplets in adipocytes, facilitated by enzymes such as hormone-sensitive lipase, triggered primarily by catecholamines and inhibited by insulin.
Lipolysis is the process by which fat cells (adipocytes) break down stored triglycerides into glycerol and free fatty acids. This process occurs when the body needs to use stored fat as a source of energy, such as during fasting, exercise, or in response to certain hormonal signals. The breakdown products of lipolysis can be used directly by cells for energy production or can be released into the bloodstream and transported to other tissues for use. Lipolysis is regulated by several hormones, including adrenaline (epinephrine), noradrenaline (norepinephrine), cortisol, glucagon, and growth hormone, which act on lipases, enzymes that mediate the breakdown of triglycerides.
Cyclic AMP-dependent protein kinases (PKA) are a family of enzymes that catalyze the phosphorylation of serine and threonine residues on target proteins, activated by binding of cyclic AMP (cAMP) to their regulatory subunits, resulting in the release and activation of the catalytic subunits.
Cyclic AMP (cAMP)-dependent protein kinases, also known as protein kinase A (PKA), are a family of enzymes that play a crucial role in intracellular signaling pathways. These enzymes are responsible for the regulation of various cellular processes, including metabolism, gene expression, and cell growth and differentiation.
PKA is composed of two regulatory subunits and two catalytic subunits. When cAMP binds to the regulatory subunits, it causes a conformational change that leads to the dissociation of the catalytic subunits. The freed catalytic subunits then phosphorylate specific serine and threonine residues on target proteins, thereby modulating their activity.
The cAMP-dependent protein kinases are activated in response to a variety of extracellular signals, such as hormones and neurotransmitters, that bind to G protein-coupled receptors (GPCRs) or receptor tyrosine kinases (RTKs). These signals lead to the activation of adenylyl cyclase, which catalyzes the conversion of ATP to cAMP. The resulting increase in intracellular cAMP levels triggers the activation of PKA and the downstream phosphorylation of target proteins.
Overall, cAMP-dependent protein kinases are essential regulators of many fundamental cellular processes and play a critical role in maintaining normal physiology and homeostasis. Dysregulation of these enzymes has been implicated in various diseases, including cancer, diabetes, and neurological disorders.
Peri-implantitis - Wikipedia
To find the pathology of peri-implantitis, experiments were compared to peri-mucositis, and found that in peri-implantitis, ... Peri-implant mucositis has the ability to transform into peri-implantitis if no action is taken to reverse signs of peri- ... Peri-implant disease is an umbrella term for inflammatory diseases of tissues including both peri-implantitis and peri-implant ... Without evidence of bone loss, the diagnosis is restricted to peri-mucositis (see comparison between peri-implantitis and peri- ...
Risk factors for periodontitis & peri-implantitis
For dental practitioners this includes periodontitis or peri-implantitis, the focus of this issue. Many risk factors are ... Risk factors for periodontitis & peri-implantitis Periodontol 2000. 2022 Oct;90(1):9-12. doi: 10.1111/prd.12447. Epub 2022 Aug ... For dental practitioners this includes periodontitis or peri-implantitis, the focus of this issue. Many risk factors are ... some of which will be the same for both periodontitis and peri-implantitis. The most recent classification of periodontal ...
Factors influencing severity of peri-implantitis
... while concomitant presence of these two risk factors did not further increase the severity of peri-implantitis, as compared to ... study indicated that smoking and a prior history of periodontitis were important risk factors for increased severity of peri- ... on the severity of peri-implantitis in patients referred for treatment of peri-implantitis. ... Factors influencing severity of peri-implantitis Clin Oral Implants Res. 2016 Jan;27(1):7-12. doi: 10.1111/clr.12505. Epub 2014 ...
Unveiling a new electrolytic treatment for peri-implantitis | FDI
Brodbeck WDC Speaker on Therapy of Peri-implantitis and Aesthetic Dentistry Tell us about the new electrolytic approach to ... What could be contributing to increasing rates of peri-implantitis?. The literature shows that the rates of peri-implantitis ... WDC Speaker on Therapy of Peri-implantitis and Aesthetic Dentistry. Tell us about the new electrolytic approach to cleaning ... The aim of my lecture is to present an overview of the different treatment options for peri-implantitis. Ill outline a ...
Association of Cytokine Gene Polymorphism with Peri-implantitis Risk - PubMed
The findings suggest that smoking and the presence of TNFα-308 GA/AA genotypes may increase the risk for peri-implantitis, ... Primary prevention of peri-implantitis: managing peri-implant mucositis. Jepsen S, Berglundh T, Genco R, Aass AM, Demirel K, ... divided into peri-implantitis (34) and healthy peri-implant tissue (64) groups. The percentage distribution of smokers was ... A positive history of periodontitis was more frequent in the peri-implantitis group (62%) than in the healthy peri-implant ...
Periodontal and Peri-Implantitis Osseous Tissue Regeneration: A GBR Protocol by Dr. Bob Convissar - Online Dental Education -...
... fully backed up by the peer-reviewed literature to achieve guided bone regeneration for periodontitis and peri-implantitis. ... Periodontal and Peri-Implantitis Osseous Tissue Regeneration: A GBR Protocol. Home > Continuing Education > Periodontal and ... This technique is also applicable to peri-implantitis treatment. Though lasers have been used in dentistry for over 30 years, ... Understand a technique for regenerating bone and fibroblast mediated soft tissue when treating peri-implantitis ...
Peri-implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid: A narrative review<...
Peri-implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid: A narrative review. Diagnostics. ... Peri-implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid: A narrative review. / Alassy, Hatem ... Peri-implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid : A narrative review. In: ... Dental implant diseases, peri-implantitis (PI) and peri-implant mucositis (PIM), have shown wide prevalence in recent studies. ...
Peri-Implantitis
Preventing and reducing risk of peri-implantitis - key topics at Perio Master Clinic 2017 - European Federation of...
How to prevent peri-implant disease and techniques that may reduce the risk that patients with implants will suffer from it ... considered to be the precursor of peri-implantitis - is a key measure for preventing the onset of peri-implantitis. ... Peri-implantitis, the main cause of such failure, has "become a public-health issue due to the huge increase in prevalence and ... Preventing and reducing risk of peri-implantitis - key topics at Perio Master Clinic 2017. Categories: Clinical Practice, ...
peri implantitis - Pictoores
Treatment for Peri-implantitis
Peri implantitis mucositis symptoms
Warning Signs of Peri-Implantitis Peri-implantitis is always preceded by a much milder condition called peri-implant mucositis ... implants affected by peri-implant mucositis and peri-implantitis. 3 Sep 2014 Mucositis and moderate forms of peri-implantitis ... Etiology: Bacterial Infection Peri implantitis (like gum disease) progresses in stages. In the early peri implantitis stages, a ... For Peri-Implantitis, gum infections, receding gums, bleeding gums, spongy gums, loose teeth sockets* Purchase Peri-Implantitis ...
Peri-implantitis Archieven - Medical Bone
Understanding the interaction of graphene-based coating on dental implants and peri-implantitis bacteria
Bacterial etiology and treatment of peri-implantitis
CERBASI, Kátia Petrasunas. Bacterial etiology and treatment of peri-implantitis. Innov. Implant. J., Biomater. Esthet. (Online) ... Whether the susceptibility for periodontitis is related to that for peri-implantitis may vary according to the implant type and ... It appears reasonable to attempt interception of destructive peri-implantitis as early as possible and to stop progression by ... The longevity of osseointegrated implants can be compromissed by occlusal overload and/or plaque-induced peri-implantitis, ...
Peri-Implantitis: What Causes Implant Failure? | 3Sixty
Learn about peri-implantitis causes, symptoms, and treatment. Improve implant procedures with advanced dental software. ... Peri-implantitis Definition of Peri-Implantitis. As the name suggests, peri-implantitis or peri-implant inflammation, is a ... Treatment of Peri-Implantitis. The vast majority of treatment strategies for peri-implantitis are similar to those used in ... Peri-Implantitis. In addition to gingival inflammation, peri-implantitis also affects the surrounding bony tissues. Since its ...
Regeneration Expert: The microbiology of peri-implantitis
What microbes trigger an especially severe course of peri-implant infection? And are microbiological tests worthwhile? An int ... Mombelli, are peri-implantitis bacteria the same as periodontitis bacteria?. Prof. Mombelli: The anaerobic mixed flora is ... Peri-implantitis does not develop due to an infection originating from an external specific highly pathogenic trigger. You can ... Do all patients have the same peri-implantitis bacteria?. Prof. Mombelli: The infection is typically a mix of bacteria that the ...
Item Detail - Don't Get Screwed by Peri-implantitis
... the importance of preventive maintenance to reduce the risk of peri-implantitis and peri-implant mucositis, and methods to ... customized supportive therapy to reduce rates of peri-implant mucositis and peri-implantitis in patients with dental implants. ... Dont Get Screwed by Peri-implantitis SAVE MONEY AND BUNDLE! This course is also offered for a discounted rate as part of a 3- ... Assess risk factors for peri-implantitis and identify high and low-risk patients before, during, and after implant placement ...
LAPIP® Laser Peri-Implantitis Treatment - Ft. Lauderdale, FL
SAVING DENTAL IMPLANTS WITH THE LASER ASSISTED PERI-IMPLANTITIS PROCEDURE (LAPIP®). Laser assisted peri-implantitis can removes ... WHAT IS PERI-IMPLANTITIS?. Many patients who come to Drs. Tom and Mark McCawley for dental implants in the Fort Lauderdale, FL ... Peri-implantitis, just like periodontal disease, develops as a result of poor oral hygiene or as a complication from certain ... Peri-implantitis is an oral infection that affects the bone and soft tissue surrounding dental implants. It is an accumulation ...
Peri-Implantitis | Lutherville-Timonium, MD | 410-252-0871
Restore your implant health and protect your oral health with our expert peri-implantitis treatment. We use the latest ... Peri-implantitis is a condition that can affect dental implant patients. It is a type of gum disease that develops around the ... If peri-implantitis is detected, our team will develop a personalized treatment plan tailored to your specific needs. Treatment ... If left untreated, peri-implantitis can lead to the need for implant removal and replacement. ...
Dental Implant Failure | Chino Hills, CA | Avion Dental | Peri-Implantitis
But in most cases, if the implant hasnt improved with peri-implantitis treatment and bone grafts, this is the best option to ... Peri-implantitis is an inflammatory condition caused by bacteria that build up around a dental implant. Similar to ... peri-implantitis treatment often includes antibiotics, surgery, and implant removal. The good news is that its treatable! We ...
Peri-implantitis in my clinic?... Ann-Marie Roos-Jansaker - EverTechnology
Peri-implantitis is difficult to treat and it is important to detect early signs of inflammation before progressive bone loss ... Peri-implantitis in my clinic?… Ann-Marie Roos-Jansaker. $13.00. - $25.00. Peri-implantitis is difficult to treat and it is ... Describe how to diagnose mucositis and peri-implantitis. • Analyze risk factors associated with peri-implant disease. • Discuss ... Home / CONFERENCE RECORDINGS / ADA2017 / Peri-implantitis in my clinic?… Ann-Marie Roos-Jansaker ...
Incidence of Peri- Implantitis among known population
| Pakistan Heart Journal
It was seen that out of 100 subjects, peri-implantitis was observed in 45 subjects. The study also found that peri-implantitis ... is associated with an increased risk of getting peri-implantitis.. Keywords: peri-implantitis, smoking, periodontal, incidence. ... Peri-implantitis is more significant in heavy smokers (7 patients) than in those who dont smoke at all (29 participants). ... Background: This study was conducted to assess the Incidence of Peri-Implantitis. ...
Subcutaneous facial emphysema following open-flap air-powder abrasive debridement for peri-implantitis: a case report and an...
... only six cases have been reported arising from peri-implant cleaning or nonsurgical peri-implantitis treatment. Therefore, the ... only six cases have been reported arising from peri-implant cleaning or nonsurgical peri-implantitis treatment. Therefore, the ... Subcutaneous facial emphysema following open-flap air-powder abrasive debridement for peri-implantitis: a case report and an ... Subcutaneous facial emphysema following open-flap air-powder abrasive debridement for peri-implantitis: a case report and an ...
What Is Peri-Implantitis? - Las Vegas Cosmetic Dentist Marielaina Perrone DDS
Peri-Implantitis Treatment Options. The course and success of treatment revolves around when the peri-implantitis is diagnosed ... or peri-implantitis. Peri-implantitis becomes a factor in patients with poor oral hygiene, diabetes, smoking, and when there is ... Peri-implantitis is a unique complication when dealing with dental implants. Dental implants have a very high success rate but ... Peri-implantitis will cause the destruction of bone and gum tissue exposing part of the dental implant to the outside. This ...
4 Effective Ways To Save Your Dental Implants From Peri-Implantitis
... 28 July 2022 Categories: Dentist, Blog ... Experts recommend reporting infections to a dentist immediately to prevent them from developing into severe peri-implantitis. ... and low bone density might increase the risks of peri-implantitis. If you experience pain, swelling, a loose implant, or ...
Peri-implantitis 1/3: anatomo-hiostological reminder and definitions. - HYGITECH Academy
Peri-implantitis. Peri-implantitis is a pathological condition of the peri-implant tissues associated with dental plaque, ... Also known as peri-implant mucosa. The peri-implant mucosa forms a barrier between the oral environment and the peri-implant ... Peri-implant tissues. Peri-implant tissues are the tissues surrounding the dental implants:. Peri-implant hard tissue and ... Periodontal tissues and peri-implantitis. The gum. The gum is one of the soft tissues lining the oral cavity. It is a ...
Evaluation of IL-4, MIP-1α, and MMP-9 gene expression levels in peri-implant tissues in peri-implantitis | Braz. dent. j...
Evaluation of IL-4, MIP-1α, and MMP-9 gene expression levels in peri-implant tissues in peri-implantitis ... factors involved in the formation of giant cells in healthy peri-implant tissue and peri-implantitis. Thirty-five subjects (15 ... Within the limitations of this study, the results showed that in tissues affected by peri-implantitis, only levels of Il-4 were ... IL-4 gene expression showed higher (18-fold) values in the Peri-Implantitis Group of Patients when compared with the Healthy ( ...
Peri-implantitis - adjunctive measures to non-surgical peri-implant therapy - National Elf Service
... were included in this review of the effectiveness of patient-performed or administered adjunctive measures to non-surgical peri ... Peri-implantitis - adjunctive measures to non-surgical peri-implant therapy. No Responses » ... Tagged with: antimicrobials, bleeding, chlorhexidine, dental implants, peri-implant disease, peri-implantitis, periodontal ... Peri-implantitis is a common problem following dental implant placement with a recent review (Dental Elf - 24th Oct 2022) ...