Persistent Hyperplastic Primary Vitreous

Eye Abnormalities

Vitreous Body

Posterior Capsulotomy

Hyperplasia

Lens, Crystalline

Cataract

Persistent fetal vasculature

Coats' disease

Axenfeld-Rieger syndrome

Welsh Corgi

Murder of Brittanee Drexel

PHPV12

• Persistent hyperplastic primary vitreous (PHPV) is also referred to as persistent fetal vasculature (PFV) or persistent fetal vasculature syndrome (PFVS), OMIM 611308 (autosomal dominant PHPV) or OMIM 611311 (autosomal recessive PHPV). (institut-vision.org)
• PHPV is a congenital anomaly of the eye that results following failure of embryological primary vitreous and hyaloid vasculature to regress. (institut-vision.org)
• The purely anterior PHPV is also known as persistent tunica vasculosa lentis and persistent posterior fetal fibrovascular sheath of the lens. (institut-vision.org)
• Persistent hyperplastic primary vitreous (PHPV), also known as persistent fetal vasculature, is a rare congenital developmental malformation of the eye, caused by the failure of regression of the primary vitreous. (nih.gov)
• Persistent hyperplastic primary vitreous (PHPV) is a congenital eye disease of children, because its clinical manifestations are nonspecific, it is easy to be misdiagnosed as congenital cataract and the prognosis is poor.There has been more researches on PHPV clinical characteristics than its histopathological feature and immunochemistry. (cjeo-journal.org)
• PHPV is usually misdiagnosed as congenital cataract and shows a poor postoperative BCVA.PHPV occurs mainly due to an incomplete regression of the embryonic vitreous and hyaloid vasculature and eventual abnormality of lens. (cjeo-journal.org)
• Persistent fetal vasculature (PFV), also known as persistent fetal vasculature syndrome (PFSV), and until 1997 known primarily as persistent hyperplastic primary vitreous (PHPV), is a rare congenital anomaly which occurs when blood vessels within the developing eye, known as the embryonic hyaloid vasculature network, fail to regress as they normally would in-utero after the eye is fully developed. (wikipedia.org)
• The situation is also called persistent fetal vasculature (Goldberg 1997 ), which has been coined as a new term and advocated to be used in place of PHPV. (springeropen.com)
• The persistent fetal vasculature or PHPV is classified largely into two types, posterior type and anterior type, based on the clinical pictures. (springeropen.com)
• Dehghan M.H., Mashayekhi A., XX1st meeting of the club Jules Gonin 28 august- 1september 1998, Edinburgh - Scotland 3 - Outcomes of surgical (pars plicata and limbal lensectomy, vitrectomy) and non-surgical management of persistent hyperplastic primary vitreous (PHPV). (drugstorepdfsearch.com)
• Following this, it has been decided by the Working Party that as of 1st January 2020 your breed will no longer be listed under Schedule B of the eye scheme for Multifocal retinal dysplasia (MRD), Persistent hyperplastic primary vitreous (PHPV), Hereditary cataracts (HC) and Persistent pupillary membranes (PPM). (southernfinnishlapphundsociety.co.uk)
• Other features that have been reported in association with HARD Syndrome include coloboma, Persistent Hyperplastic Primary Vitreous (PHPV) also known as Persistent Fetal Vasculature, cataracts, glaucoma, buphthalmos, anterior chamber dysgenesis, optic atrophy, and optic nerve hypoplasia. (mhmedical.com)

Vasculature7

• Persistent fetal vasculature heightens the lifelong risk of glaucoma, cataracts, intraocular hemorrhages, and Retinal detachments, accounting for the visual loss of nearly 5% of the blind community in the developed world. (wikipedia.org)
• The presentation of persistent fetal vasculature is generally classified into three forms: purely anterior, purely posterior, or a mix of both. (wikipedia.org)
• Persistent fetal vasculature manifests exclusively in newborn infants, generally within two weeks of birth, although it may not be diagnosed until much later. (wikipedia.org)
• The spectrum of NDP -related retinopathies appears to be a continuum with considerable overlap, ranging from Norrie disease, NDP -related persistent fetal vasculature, NDP -related familial exudative vitreoretinopathy, NDP -related advanced retinopathy of prematurity, and NDP -related Coats disease. (nih.gov)
• A developmental ocular anomaly in which the primary VITREOUS BODY and its surrounding hyaloid vasculature failed to regress. (nih.gov)
• To describe the incidence of unilateral congenital cataract associated with minimal (ultrasonically undetectable) levels of persistent fetal vasculature in the first 18 months of the life and to report surgical methods for intraocular lens implantation, using 25-gauge vitrectomy system. (springeropen.com)
• Unilateral congenital cataract in the first 12 months of the life has a high incidence for the association with anterior type of persistent fetal vasculature which could not be detected by preoperative ultrasound examinations. (springeropen.com)

Posterior3

• It has previously been called persistent tunica vasculosa lentis, persistent posterior fetal fibrovascular sheath of the lens, congenital retinal septum, and ablatio falciformis congenita. (institut-vision.org)
• The indications included congenital rubella cataract with microphthalmos, traumatic cataract, persistent anterior and posterior hyperplastic primary vitreous, postcataract pupillary membranes, and postcataract vitreous prolapse with cystoid mascular edema. (nih.gov)
• In contrast, 3 children with unilateral cataract at the age younger than 12 months showed white fibrous tissue in the anterior vitreous integrated with the posterior lens capsule while the other 3 children with unilateral cataract at the age from 12 to 18 months did not have vitreous abnormalities. (springeropen.com)

Retinoblastoma2

• Retinoblastoma is the most common primary cancer of the eye occurring in childhood , with a frequency of 1:14,000 to 1:20,000 live births depending on the country, and accounts for 3% of all childhood cancers. (medindia.net)
• These second primary malignancies are the most common cause of death following retinoblastoma in developed countries. (medindia.net)

Abnormalities2

• Abnormalities of the zonular fibers that normally hold the lens in position may occur, resulting in luxation of the lens from its normal position into the anterior chamber or into the vitreous humor. (vin.com)
• No patient showed vitreous abnormalities on ultrasound examinations before the surgery. (springeropen.com)

Glaucoma8

• It is characterized by persistence of various portions of the primary vitreous (embryonic hyaloid vascular system) with hyperplasia of the associated embryonic connective tissue, and associated with microphthalmia, cataract and glaucoma. (institut-vision.org)
• Liang YB, Wang NL, Rong SS, Thomas R. Initial Treatment for Primary Angle-Closure Glaucoma in China. (medscape.com)
• Scanning electron microscopy of the trabecular meshwork: understanding the pathogenesis of primary angle closure glaucoma. (medscape.com)
• This entity is one of a group of pediatric glaucomas known as primary developmental glaucoma. (medscape.com)
• There are two types of inherited glaucoma, Primary Closed Angle Glaucoma (PCAG/PACG) and Primary Open Angle Glaucoma (POAG). (bva.co.uk)
• R V C, S K, Venkatesh R, Shankar L G. Persistent Pupillary Membrane and Secondary Angle Closure Glaucoma: A Case Report. (pediatriconcall.com)
• The prevalence of primary congenital glaucoma (PCG) is one in 3,300 live births and PCG accounts for 4.2% of all childhood blindness in Indian population.5 We report a rare case of unilateral persistent pupillary membrane with secondary glaucoma in a child. (pediatriconcall.com)
• Elevated intraocular pressure (IOP) is the only modifiable risk factor for primary open-angle glaucoma (POAG). (bvsalud.org)

Cataract2

• Primary glaucomas are congenital and can be associated with syndromes whereas secondary glaucomas are associated with other ocular comorbidities like uveitis, congenital cataract surgery. (pediatriconcall.com)
• Ten children with bilateral cataract underwent lensectomy in both eyes with a 25-gauge vitreous cutter under irrigation with a 25-gauge infusion cannula, inserted from two side ports at the corneal limbus. (springeropen.com)

Hereditary1

• The disorder known as persistent hyperplastic primary vitreous is generally not considered hereditary since it usually occurs unilaterally and sporadically. (arizona.edu)

Syndrome1

• Persistent Fetal Vascular Syndrome is also known as Persistent Hyperplastic Primary Vitreous that can cause a traction retinal detachment difficult to differentiate but typically unilateral. (wikidoc.org)

Lens3

• The fluids in the eye are divided by the lens into the vitreous humor (behind the lens) and the aqueous humor (in front of the lens). (mountsinai.org)
• The lens is seated in the patellar fossa, a shallow depression in the vitreous body. (vin.com)
• Anterior segment evaluation showed redness, increased size of the cornea compared to LE, brownish strands of tissue covering the pupil, arranged in a cart wheel manner suggestive of persistent pupillary membrane (PPM), clear lens in RE (Figure 1). (pediatriconcall.com)

Cataracts1

• In contrast, unilateral cataracts are sporadic and sometimes associated with other anomalies such as persistent hyperplastic primary vitreous (Morrison et al. (springeropen.com)

Pupillary membrane2

• On examination he had larger cornea, brownish strands of tissue arranged in a cartwheel pattern suggestive of persistent pupillary membrane (PPM) in pupillary area in RE. (pediatriconcall.com)
• Persistent pupillary membrane (PPM) represents a relatively common congenital ocular anomaly seen in 95% of neonates and 20% of adult population 1 that appears as fine iris strands along the pupil. (pediatriconcall.com)

Cavity1

• Theories suggest a mechanical loss of support to the trabecular meshwork (TM) after a lensectomy, in addition to the chemical alteration of the TM morphology and gene expression due to inflammatory mediators from the vitreous cavity. (eyewiki.org)

Corneal1

• Corneal opacity is observed from birth in Peters anomaly and is the primary cause for reduced visual acuity (VA). The corneal opacity may obstruct the central visual axis, causing sensory deprivation amblyopia. (gene.vision)

Vascular1

• Research undertaken in this lab examined the role of p19Arf in vascular remodeling and development of the disease persistent hyperplastic primary vitreous. (nih.gov)

Dysplasia1

• Persistent hyperplastic main vitreous and recessive oculo-dento-osseous dysplasia. (thequantumdrift.com)

Leukocoria2

• The most common cause of leukocoria is the primary vitreous used in the formation of the eye during fetal development, which in PFV remains in part or in whole within the eye upon birth, and whose tissue is hazy and scarred. (wikipedia.org)
• Some patients in addition have a vascularized hyperplastic vitreous and often present with blindness and a congenital leukocoria. (arizona.edu)

Secondary1

• 4 Paediatric glaucomas can be either primary or secondary. (pediatriconcall.com)

Limbal1

• Mashayekhi A., Ahamdieh H., soheilian M.,Azarmina M., Dehghan M.H. 5th Iranian congress of ophthalmology Thran IR iran 1995 9 - Primary capsulectomy and anterior vitrectomy combined with lensectomy and PCIOL implantation in children: limbal VS pars plana approach. (drugstorepdfsearch.com)

Uveitis1

• DEFINITION Masquerade syndromes comprise a group of disorders - simulating a chronic idiopathic uveitis - having an underlying primary cause that is not immune mediated and that is associated with an apparent clinical picture of intraocular inflammation They are usually poorly, if not at all, responsive to corticosteroid treatment. (kipdf.com)

Angle2

• Peripheral anterior synechia reduce extent of angle widening after laser peripheral iridotomy in eyes with primary angle closure. (medscape.com)
• Phacoemulsification and goniosynechialysis in the management of unresponsive primary angle closure. (medscape.com)

Consult1

• Your experience may be different from others, and you should consult your primary care provider (PCP) for more information. (nih.gov)

Data1

• The second day of the meeting will be devoted to critical assessment of the health effects that can be justifiably attributed to asbestos and vitreous fibers and to identifying critical data gaps and research needs that would further enlighten this subject (Topics #2 and #3). (cdc.gov)

Rare1

• Evidence for autosomal dominant inheritance of persistent hyperplastic primary vitreous comes from rare families with an apparent vertical transmission of the condition. (arizona.edu)

Care2

• An 11 year old boy presented to our primary eye care centre with defective vision in right eye (RE), which he realized accidentally while closing his left eye (LE). (pediatriconcall.com)
• The SBT is currently a popular breed in the UK, recently identified as the second most common purebred in the wider general dog population under primary veterinary care [ 2 ]. (biomedcentral.com)