'Pleural diseases' is a broad term referring to various medical conditions that affect the pleura, the thin, double-layered membrane surrounding the lungs, including inflammation (pleurisy), effusions (excess fluid buildup), thickening, or tumors, which may cause chest pain, coughing, and breathing difficulties.
A form of pneumoconiosis caused by inhalation of asbestos fibers which elicit potent inflammatory responses in the parenchyma of the lung. The disease is characterized by interstitial fibrosis of the lung, varying from scattered sites to extensive scarring of the alveolar interstitium.
The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.
Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms.
Endoscopic examination, therapy or surgery of the pleural cavity.
INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
Endoscopes for examining the pleural cavity.
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.
Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.
Tuberculosis of the serous membrane lining the thoracic cavity and surrounding the lungs.
Pathological processes involving any part of the LUNG.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.
Diseases caused by factors involved in one's employment.

Magnetic resonance appearance of asbestos-related benign and malignant pleural diseases. (1/296)

OBJECTIVES: This study describes the magnetic resonance findings of benign and malignant pleural diseases in asbestos-exposed subjects. METHODS: Thirty patients with a history of asbestos exposure and pleural lesions in chest X-rays and computed tomography scans were examined with a 0.5- and a 1.5-T magnetic resonance unit. The examination protocol included cardiac-gated proton density and T2-weighted images, unenhanced and enhanced (Gd-DTPA; 0.1 mmol/ kg) T1-weighted images in the axial plane and sometimes in another orthogonal plane (sagittal or coronal or both). All the magnetic resonance images were reviewed by 3 experienced observers, who visually evaluated morphologic features, signal intensity, and contrast enhancement of pleural lesions. The diagnosis was established by means of percutaneous biopsy, thoracotomy, and combined clinical and radiological follow-up for at least 3 years. RESULTS: Eighteen patients affected with multiple pleural plaques showed low signal intensity on both unenhanced and enhanced T1-weighted and proton density and T2-weighted images. In 2 of these patients an acute pleural effusion was observed. All the malignant lesions (11 mesotheliomas) and a solitary benign pleural plaque revealed high signal intensity on the proton density and T2-weighted images and inhomogeneous contrast enhancement in the postcontrast T1-weighted images. The sensitivity, specificity, and diagnostic accuracy of the magnetic resonance imaging in classifying a lesion as suggestive of malignancy were 100%, 95% and 97%, respectively. CONCLUSIONS: The results point out 2 magnetic resonance signal intensity patterns for asbestos-related pleural lesions: (i) low-signal intensity on unenhanced and enhanced T1-weighted and proton density and T2-weighted images for benign plaques and (ii) nonhomogeneous hyperintensity in T2-weighted and enhanced T1-weighted images for malignant mesotheliomas.  (+info)

Suction curettage for removal of retained intrathoracic blood clots and pleural lesions. (2/296)

OBJECTIVE: To develop a thoracoscopic technique for correcting and/or removing an intrathoracic disease process using our existing operating room equipment and without a "small thoracotomy." METHODS AND PROCEDURES: Fifty-eight patients from October 1994 to April 1998 were prospectively studied. All were undergoing procedures involving the removal of a suspected benign (or infectious) pleural process or a retained blood clot. Three or four thoracic ports were used in all cases. Straight and curved suction curettage cannulae (with finger valve attachment) ranging from 8 to 16 French were available for use. Intermittent variable suction (between zero and 60 mm Hg) was used in all cases. Dependent upon the size and adherence of the lesion to be removed, the pressure was determined by the surgeon and regulated by the circulating nurse in the room. In each case, a trap system was used for retrieval of the specimen. One lung ventilation was used in every case, and when suction was used one of the ports was kept "open" to allow room air to enter the chest cavity. RESULTS: All patients in our series had their procedures completed without the need for any kind of open thoracotomy. Pre and postoperative diagnosis concurred in all 10 patients, and no complications occurred (specifically, no injury to the lung tissue or chest wall structures). Operative time ranged from 45 minutes to 180 minutes with a mean of 75 minutes. In all cases of a hemothorax, a cell saver system was used for an average of one unit of blood autotransfused per case. CONCLUSIONS: New techniques do not always require the purchase of new equipment. Tight hospital budgets are forcing surgeons to rely on redefining uses of instrumentation already available in solving surgical problems. We believe that the use of this instrumentation will provide another avenue for surgeons to successfully complete a procedure thoracoscopically without the need for a thoracotomy. It is through multidisciplinary conferences such as the Society of Laparoendoscopic Surgeons that ideas such as this are propagated.  (+info)

Increased serum concentrations of growth factor receptors and Neu in workers previously exposed to asbestos. (3/296)

OBJECTIVES: Epidermal growth factor receptor (EGFR) and oncogene Neu belong to a family of growth factor receptors which may play a part in carcinogenesis. Although increased serum concentrations of Neu and EGFR have been shown in several patients with asbestosis who later developed cancer, serum concentrations have not been studied in workers exposed in the past to asbestos but without asbestos related diseases. METHODS: Serum concentrations of secreted growth factor receptors were studied in 300 workers exposed in the past to asbestos and the results were compared with those of 70 controls. RESULTS: In the controls 4.3% (3/70) had EGFR values > 912 units/ml, compared with 39% (117/299) of the exposed group (p < 0.001). The difference in high values was even more pronounced for Neu with 4.3% of controls having Neu values > 2580 fmol/ml compared with 72% (216/299) of the exposed workers (p < 0.001). Pleural plaques predicted lower serum concentrations of EGFR but not lower Neu concentrations, and this finding remained significant after adjustment for age, exposure time, smoking, and time from initial exposure. CONCLUSIONS: Enhanced secretion of EGFR and Neu was found in a large cohort of retired asbestos workers with a wide range of exposure and latency periods. They did not have asbestosis or cancer and their EGFR values were higher in those without plaques. Further studies are needed to confirm our results, to determine the source of the secreted growth factor receptors, and to study their possible value as risk factors in the development of cancer.  (+info)

Carboxyterminal propeptide of type I procollagen in ELF: elevation in asbestosis, but not in pleural plaque disease. (4/296)

Markers of collagen metabolism may possibly be used in the assessment of pulmonary involvement in asbestosis-related pulmonary diseases. In this study the levels of the carboxyterminal propeptide of type I procollagen (PICP) and the aminoterminal propeptide of type III procollagen (PIIINP) were evaluated in bronchoalveolar lavage fluid (BALF), epithelial lining fluid (ELF) and serum from patients with asbestos related pulmonary and pleural involvement. Forty-two consecutive patients with occupational exposure to asbestos fibres, who underwent bronchoscopy and bronchoalveolar lavage (BAL) at the time of the diagnosis were investigated. Five patients were diagnosed as having asbestosis, while 37 showed no parenchymal involvement. Of the latter group, 25 had pleural plaques, while 12 had no detectable changes in chest radiographs. The patients were followed-up for an average of 7 yrs. The PICP in BALF and ELF was detectable in all patients with asbestosis and in 8/37 subjects without parenchymal involvement. The levels of PICP in BALF and ELF were significantly higher in the asbestosis group compared to the patients without asbestosis (9.8+/-1.8 microg x L(-1) versus 0.6+/-1.3 microg x L(-1), p<0.001 and 488.9+/-208.8 microg x L(-1) versus 22.6+/-50.6 microg x L(-1), p<0.001, respectively). Only 1 patient with asbestosis and 3 patients without parenchymal involvement had detectable levels of PIIINP in BALF. The serum levels of PICP and PIIINP did not differ between the patients with asbestosis and those with exposure to asbestos fibres without asbestosis and were within the normal range. None of the 37 patients exposed to asbestos fibres without parenchymal involvement at the baseline developed asbestosis during the follow-up period of 7 yrs. In conclusion, the data show that the carboxyterminal propeptide of procollagen type I, but not the aminoterminal propeptide of type III procollagen is highly elevated in bronchoalveolar lavage fluid and epithelial lining fluid in patients with asbestosis, but not in those without parenchymal involvement. This suggests that the determination of carboxyterminal propeptide of procollagen type I in bronchoalveolar lavage fluid could be used as a marker of parenchymal involvement in patients exposed to asbestos fibres.  (+info)

Familial extensive idiopathic bilateral pleural fibrosis. (5/296)

The authors report three sisters with bilateral isolated apical pleural fibrosis of unknown origin, which did not respond to empirical antituberculosis therapy and oral corticosteroids. The disease evolved in an unrelenting fashion producing pleural fibrosis at the lung bases and leading to the death of two sisters and to lung transplantation in the other one. There was no history of other familial disease or consanguinity. The particular features of these cases and the differences from other reports of apparently cryptogenic pleural fibrosis are outlined.  (+info)

Mortality due to asbestos-related causes among railway carriage construction and repair workers. (6/296)

The objective of this study was to further clarify the cancer risk associated with asbestos exposure in railway carriage construction and repair. The cohort included 734 subjects employed between 1 January 1945 and 31 December 1969. Vital status was ascertained at 31 December 1997. Mortality was investigated in the time span 1970-97. Forty-two subjects (6%) were lost to follow-up and eight causes of death (4%) could not be ascertained. The overall mortality was not above the expected value. Among neoplastic diseases, excesses were observed for lung standardized mortality ratio (SMR) = 124; 90% confidence interval (CI) = 87-172; 26 obs), pleura (SMR = 1,327; CI = 523-2,790; 5 obs), larynx (SMR = 240; CI = 95-505; 5 obs), liver (SMR = 241; CI = 126-420; 9 obs), pancreas (SMR = 224; CI = 98-443; 6 obs) and multiple myeloma (SMR = 429; CI = 117-1,109; 3 obs). The observed excess of lung and pleural neoplasms can be causally related to asbestos exposure in the manufacture of railway carriages. A causal role of asbestos exposure in the raised SMRs from laryngeal and pancreatic neoplasms and multiple myeloma cannot be conclusively proven.  (+info)

High-resolution computed tomography in cases with environmental exposure to asbestos in Turkey. (7/296)

BACKGROUND AND OBJECTIVES: Although all parts of the lung can be affected as a consequence of asbestos exposure, most CT protocols tend to scan only the middle and lower parts of the thorax. The aim of this study was to investigate parenchymal and pleural lesions of persons exposed to environmental asbestos, using a high-resolution computed tomography (HRCT) protocol scanning the whole thorax. METHODS: We analyzed the chest radiographs and HRCT scans of 26 patients who presented bilaterally with multiple pleural plaques related to environmental asbestos exposure. RESULTS: Twenty-four cases (92%) had an abnormal HRCT suggestive of asbestosis. Apart from common HRCT changes related to asbestosis, we detected apical pleural thickening (APT) in 9 cases as well as a coarse honeycomb pattern adjacent to APT in 7 of these cases. Cavitary lesions due to pulmonary tuberculosis were observed on HRCT scans from 4 patients in total. Neither apical pulmonary fibrosis nor cavitary lesions were visible on chest radiographs. CONCLUSIONS: We suggest that the HRCT protocol for examining asbestos-exposed individuals with pleural plaques on chest X-rays should include the whole thorax, since the asbestos-related pathologies may involve all parts of the lung.  (+info)

Pulmonary calcifications: a review. (8/296)

Pulmonary calcification is a common asymptomatic finding, usually discovered on routine chest X-ray or at autopsy. Pulmonary calcifications are caused mainly by two mechanisms: the dystrophic form and the metastatic form (1). Despite the different aetiologies, the pulmonary function and clinical manifestations are quite similar in both forms. We present a review of the clinical and radiology findings of the different aspects of pulmonary calcifications according to its pathogenesis and its anatomic distribution: parenchymal, lymphe node and pleural.  (+info)

Pleural diseases refer to conditions that affect the pleura, which is the thin, double-layered membrane that surrounds the lungs and lines the inside of the chest wall. The space between these two layers contains a small amount of fluid that helps the lungs move smoothly during breathing. Pleural diseases can cause inflammation, infection, or abnormal collections of fluid in the pleural space, leading to symptoms such as chest pain, cough, and difficulty breathing.

Some common examples of pleural diseases include:

1. Pleurisy: Inflammation of the pleura that causes sharp chest pain, often worsened by breathing or coughing.
2. Pleural effusion: An abnormal accumulation of fluid in the pleural space, which can be caused by various underlying conditions such as heart failure, pneumonia, cancer, or autoimmune disorders.
3. Empyema: A collection of pus in the pleural space, usually resulting from a bacterial infection.
4. Pleural thickening: Scarring and hardening of the pleura, which can restrict lung function and cause breathlessness.
5. Mesothelioma: A rare form of cancer that affects the pleura, often caused by exposure to asbestos.
6. Pneumothorax: A collection of air in the pleural space, which can result from trauma or a rupture of the lung tissue.

Proper diagnosis and treatment of pleural diseases require a thorough evaluation by a healthcare professional, often involving imaging tests such as chest X-rays or CT scans, as well as fluid analysis or biopsy if necessary.

Asbestosis is a chronic lung disease that is caused by the inhalation of asbestos fibers. It is characterized by scarring (fibrosis) of the lung tissue, which can lead to symptoms such as shortness of breath, coughing, and chest pain. The severity of the disease can range from mild to severe, and it is often progressive, meaning that it tends to worsen over time. Asbestosis is not a malignant condition, but it can increase the risk of developing lung cancer or mesothelioma, which are forms of cancer that are associated with asbestos exposure. The disease is typically diagnosed through a combination of medical history, physical examination, and imaging tests such as chest X-rays or CT scans. There is no cure for asbestosis, but treatment can help to manage the symptoms and slow the progression of the disease.

The pleura is the medical term for the double-layered serous membrane that surrounds the lungs and lines the inside of the chest cavity. The two layers of the pleura are called the parietal pleura, which lines the chest cavity, and the visceral pleura, which covers the surface of the lungs.

The space between these two layers is called the pleural cavity, which contains a small amount of lubricating fluid that allows the lungs to move smoothly within the chest during breathing. The main function of the pleura is to protect the lungs and facilitate their movement during respiration.

Pleural effusion is a medical condition characterized by the abnormal accumulation of fluid in the pleural space, which is the thin, fluid-filled space that surrounds the lungs and lines the inside of the chest wall. This space typically contains a small amount of fluid to allow for smooth movement of the lungs during breathing. However, when an excessive amount of fluid accumulates, it can cause symptoms such as shortness of breath, coughing, and chest pain.

Pleural effusions can be caused by various underlying medical conditions, including pneumonia, heart failure, cancer, pulmonary embolism, and autoimmune disorders. The fluid that accumulates in the pleural space can be transudative or exudative, depending on the cause of the effusion. Transudative effusions are caused by increased pressure in the blood vessels or decreased protein levels in the blood, while exudative effusions are caused by inflammation, infection, or cancer.

Diagnosis of pleural effusion typically involves a physical examination, chest X-ray, and analysis of the fluid in the pleural space. Treatment depends on the underlying cause of the effusion and may include medications, drainage of the fluid, or surgery.

Pleural neoplasms refer to abnormal growths or tumors that develop in the pleura, which is the thin, double layered membrane that surrounds the lungs and lines the inside of the chest wall. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Malignant pleural neoplasms are often associated with lung cancer, mesothelioma, or metastasis from other types of cancer. They can cause symptoms such as chest pain, cough, shortness of breath, and weight loss. Diagnosis typically involves imaging tests like X-rays or CT scans, followed by biopsy to confirm the type of tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Thoracoscopy is a surgical procedure in which a thoracoscope, a type of endoscope, is inserted through a small incision between the ribs to examine the lungs and pleural space (the space surrounding the lungs). It allows the surgeon to directly view the chest cavity, take biopsies, and perform various operations. This procedure is often used in the diagnosis and treatment of pleural effusions, lung cancer, and other chest conditions.

Pleurisy is a medical condition characterized by inflammation of the pleura, which are the thin membranes that surround the lungs and line the inside of the chest cavity. The pleura normally produce a small amount of lubricating fluid that allows for smooth movement of the lungs during breathing. However, when they become inflamed (a condition known as pleuritis), this can cause pain and difficulty breathing.

The symptoms of pleurisy may include sharp chest pain that worsens with deep breathing or coughing, shortness of breath, cough, fever, and muscle aches. The pain may be localized to one area of the chest or may radiate to other areas such as the shoulders or back.

Pleurisy can have many different causes, including bacterial or viral infections, autoimmune disorders, pulmonary embolism (a blood clot that travels to the lungs), and certain medications or chemicals. Treatment typically involves addressing the underlying cause of the inflammation, as well as managing symptoms such as pain and breathing difficulties with medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) or opioids. In some cases, more invasive treatments such as thoracentesis (removal of fluid from the chest cavity) may be necessary.

A thoracoscope is not a medical condition, but a medical device used in the field of thoracic surgery. It is a type of endoscope that allows surgeons to view the inside of the chest cavity (thorax) through small incisions. The thoracoscope has a light source and a camera at its tip, which transmits images to a video monitor. This enables the surgeon to inspect the lungs, pleura, mediastinum, and diaphragm, take biopsies, and perform various surgical procedures, such as pleurodesis or lung resection, minimizing invasiveness and promoting faster recovery compared to traditional open thoracotomy.

Mesothelioma is a rare and aggressive form of cancer that develops in the mesothelial cells, which are the thin layers of tissue that cover many of the internal organs. The most common site for mesothelioma to occur is in the pleura, the membrane that surrounds the lungs. This type is called pleural mesothelioma. Other types include peritoneal mesothelioma (which occurs in the lining of the abdominal cavity) and pericardial mesothelioma (which occurs in the lining around the heart).

Mesothelioma is almost always caused by exposure to asbestos, a group of naturally occurring minerals that were widely used in construction, insulation, and other industries because of their heat resistance and insulating properties. When asbestos fibers are inhaled or ingested, they can become lodged in the mesothelium, leading to inflammation, scarring, and eventually cancerous changes in the cells.

The symptoms of mesothelioma can take many years to develop after exposure to asbestos, and they may include chest pain, coughing, shortness of breath, fatigue, and weight loss. Treatment options for mesothelioma depend on the stage and location of the cancer, but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Unfortunately, the prognosis for mesothelioma is often poor, with a median survival time of around 12-18 months after diagnosis.

Asbestos is a group of naturally occurring mineral fibers that are resistant to heat, chemical reactions, and electrical currents. There are six types of asbestos, but the most common ones are chrysotile, amosite, and crocidolite. Asbestos has been widely used in various construction materials, such as roofing shingles, ceiling and floor tiles, paper products, and cement products.

Exposure to asbestos can cause serious health problems, including lung cancer, mesothelioma (a rare form of cancer that affects the lining of the lungs, heart, or abdomen), and asbestosis (a chronic lung disease characterized by scarring of the lung tissue). These health risks are related to the inhalation of asbestos fibers, which can become lodged in the lungs and cause inflammation and scarring over time.

As a result, the use of asbestos has been heavily regulated in many countries, and its use is banned in several others. Despite these regulations, asbestos remains a significant public health concern due to the large number of buildings and products that still contain it.

Malignant pleural effusion is a medical condition characterized by the abnormal accumulation of fluid in the pleural space (the area between the lungs and the chest wall) due to the spread of malignant (cancerous) cells from a primary tumor located elsewhere in the body. This type of effusion is typically associated with advanced-stage cancer, and it can cause symptoms such as shortness of breath, coughing, and chest pain. The presence of malignant pleural effusion often indicates a poor prognosis, and treatment is generally focused on palliating symptoms and improving quality of life.

Pleural Tuberculosis is a form of extrapulmonary tuberculosis (EPTB) that involves the infection and inflammation of the pleura, which are the thin membranes that surround the lungs and line the inside of the chest cavity. This condition is caused by the Mycobacterium tuberculosis bacterium, which can spread through the air when an infected person coughs, sneezes, or talks.

In pleural tuberculosis, the bacteria reach the pleura either through direct extension from a nearby lung infection or via bloodstream dissemination. The infection can cause the pleura to become inflamed and produce excess fluid, leading to pleural effusion. This accumulation of fluid in the pleural space can cause chest pain, coughing, and difficulty breathing.

Diagnosis of pleural tuberculosis typically involves a combination of medical history, physical examination, imaging studies such as chest X-rays or CT scans, and laboratory tests such as acid-fast bacilli (AFB) smear microscopy, culture, and nucleic acid amplification tests (NAATs) to detect the presence of M. tuberculosis in the pleural fluid or tissue samples.

Treatment of pleural tuberculosis typically involves a standard course of anti-tuberculosis therapy (ATT), which includes a combination of multiple antibiotics such as isoniazid, rifampin, ethambutol, and pyrazinamide. The duration of treatment may vary depending on the severity of the infection and the patient's response to therapy. In some cases, surgical intervention may be necessary to drain the pleural effusion or remove the infected pleura.

Lung diseases refer to a broad category of disorders that affect the lungs and other structures within the respiratory system. These diseases can impair lung function, leading to symptoms such as coughing, shortness of breath, chest pain, and wheezing. They can be categorized into several types based on the underlying cause and nature of the disease process. Some common examples include:

1. Obstructive lung diseases: These are characterized by narrowing or blockage of the airways, making it difficult to breathe out. Examples include chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, and cystic fibrosis.
2. Restrictive lung diseases: These involve stiffening or scarring of the lungs, which reduces their ability to expand and take in air. Examples include idiopathic pulmonary fibrosis, sarcoidosis, and asbestosis.
3. Infectious lung diseases: These are caused by bacteria, viruses, fungi, or parasites that infect the lungs. Examples include pneumonia, tuberculosis, and influenza.
4. Vascular lung diseases: These affect the blood vessels in the lungs, impairing oxygen exchange. Examples include pulmonary embolism, pulmonary hypertension, and chronic thromboembolic pulmonary hypertension (CTEPH).
5. Neoplastic lung diseases: These involve abnormal growth of cells within the lungs, leading to cancer. Examples include small cell lung cancer, non-small cell lung cancer, and mesothelioma.
6. Other lung diseases: These include interstitial lung diseases, pleural effusions, and rare disorders such as pulmonary alveolar proteinosis and lymphangioleiomyomatosis (LAM).

It is important to note that this list is not exhaustive, and there are many other conditions that can affect the lungs. Proper diagnosis and treatment of lung diseases require consultation with a healthcare professional, such as a pulmonologist or respiratory therapist.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

Occupational exposure refers to the contact of an individual with potentially harmful chemical, physical, or biological agents as a result of their job or occupation. This can include exposure to hazardous substances such as chemicals, heavy metals, or dusts; physical agents such as noise, radiation, or ergonomic stressors; and biological agents such as viruses, bacteria, or fungi.

Occupational exposure can occur through various routes, including inhalation, skin contact, ingestion, or injection. Prolonged or repeated exposure to these hazards can increase the risk of developing acute or chronic health conditions, such as respiratory diseases, skin disorders, neurological damage, or cancer.

Employers have a legal and ethical responsibility to minimize occupational exposures through the implementation of appropriate control measures, including engineering controls, administrative controls, personal protective equipment, and training programs. Regular monitoring and surveillance of workers' health can also help identify and prevent potential health hazards in the workplace.

Occupational diseases are health conditions or illnesses that occur as a result of exposure to hazards in the workplace. These hazards can include physical, chemical, and biological agents, as well as ergonomic factors and work-related psychosocial stressors. Examples of occupational diseases include respiratory illnesses caused by inhaling dust or fumes, hearing loss due to excessive noise exposure, and musculoskeletal disorders caused by repetitive movements or poor ergonomics. The development of an occupational disease is typically related to the nature of the work being performed and the conditions in which it is carried out. It's important to note that these diseases can be prevented or minimized through proper risk assessment, implementation of control measures, and adherence to safety regulations.

Pleural sarcomas Pleural angiosarcoma Pleural desmoplastic small round cell tumor (pleural DSRCT) Pleural synovial sarcoma ... Pleural disease occurs in the pleural space, which is the thin fluid-filled area in between the two pulmonary pleurae in the ... embolism Pleurisy Pneumonia Pleural infections Pleural endometriosis Pleuritis Pleural mesothelial hyperplasia Pleural ... calcified fibrous pseudotumor Pleural thickening, including pleural plaques Pleural cavity "Pleural Tumors - Health ...
There are currently no human or mouse genes associated with this disease in the MGI database. Synonyms: Mesothelioma of Pleura ... Disease Ontology Browser benign pleural mesothelioma (DOID:5157) Alliance: disease page Synonyms: Mesothelioma of Pleura Alt ...
Eosinophilic Pleural Effusion in Gnathostomiasis. Emerging Infectious Diseases. 2004;10(9):1690-1691. doi:10.3201/ ... disclosed only two references to pleural effusion as the main symptom of gnathostomiasis (4,5). The eosinophilic pleural and ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Eosinophilic Pleural Effusion in Gnathostomiasis. Volume 10, Number 9-September 2004. Article Views: 339. Data is collected ...
Pleural disease. Clinical context. Pleural disease remains common, affecting over 3000 people per million population each year ... Value of serum and pleural fluid biomarkers in distinguishing underlying cause of pleural disease reducing the need for ... Pleural disease originates from a wide range of pathologies and a systematic approach to the investigation and management is ... The objective was to produce an evidence-based update of the last pleural disease guidelines published in 2003. It was ...
Introduction and methods: British Thoracic Society pleural disease guideline 2010 Message subject: (Your Name) has forwarded a ...
... ... A total of 20 patients had disease diagnosed correctly, nine had disease diagnosed incorrectly, and two cases were undetermined ... imaging for differentiating benign lesions from malignant pleural disease (MPD) and to retrospectively assess dynamic contrast ... DW imaging helped stage disease correctly in 27 patients and incorrectly in four. The undetermined cases at PET/CT were ...
Treatment of pleural cavity disease varies depending on the underlying etiology. For traumatic pneumothorax, intermittent ... Management of Pleural Effusion. Animals with pleural air or fluid usually exhibit a restrictive respiratory pattern (i.e., ... However, most animals with pleural cavity disease benefit from intermittent positive pressure ventilation and oxygen ... should be performed prior to taking radiographs in severely dyspneic animals with suspected pleural cavity disease. Removal of ...
Asbestos-Related Pleural Disease - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - ... including pleural effusion, pleural plaques, and pleural thickening. Nonmalignant asbestos-related pleural disease is more ... Chest CT can distinguish pleural disease from parenchymal disease and pleural fat. The latency from time of exposure to ... Analysis of the pleural effusion Pleural Effusion Pleural effusions are accumulations of fluid within the pleural space. They ...
Advanced medical interventions in pleural disease Rahul Bhatnagar, John P. Corcoran, Fabien Maldonado, David Feller-Kopman, ... Malignant pleural effusion: from bench to bedside Ioannis Psallidas, Ioannis Kalomenidis, Jose M. Porcel, Bruce W. Robinson, ... The management of benign non-infective pleural effusions Oliver J. Bintcliffe, Gary Y.C. Lee, Najib M. Rahman, Nick A. Maskell ... Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment Anna C. Bibby, Selina Tsim, Nikolaos ...
Asbestos-Related Pleural Disease - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - ... including pleural effusion, pleural plaques, and pleural thickening. Nonmalignant asbestos-related pleural disease is more ... Chest CT can distinguish pleural disease from parenchymal disease and pleural fat. The latency from time of exposure to ... Analysis of the pleural effusion Pleural Effusion Pleural effusions are accumulations of fluid within the pleural space. They ...
The pleura is a double membrane that surrounds the lungs and lines the inside of the thoracic cavity. Disorders of the pleura may be inflammatory, infectious or cancerous.
Pleural disorders include pleurisy, pleural effusion and pneumothorax. Learn more. ... ClinicalTrials.gov: Pleural Diseases (National Institutes of Health) * ClinicalTrials.gov: Pleural Effusion (National ... Pleural Fluid Analysis (National Library of Medicine) Also in Spanish * Tests for Lung Disease (National Heart, Lung, and Blood ... The most common cause of pleural effusion is congestive heart failure. Lung diseases, like COPD, tuberculosis, and acute lung ...
It is the most common manifestation of pleural disease. ... A pleural effusion is an abnormal collection of fluid in the ... pleural space resulting from excess fluid production or decreased absorption. ... 1] It is the most common manifestation of pleural disease. The pleural space is bordered by the parietal and visceral pleurae. ... Management of a malignant pleural effusion: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010 Aug. 65 Suppl ...
"Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases" vol. 18, no. 2, 2012. Export RIS ... 2012). Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases. 18(2). Antao, Vinicius C. ... Title : Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases Personal Author(s) : Antao ... Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases. ...
Pleural Disease. This episode dives into the physiology and pathophysiology of pleural disease, as well as a step-wise approach ... Pleural Disease. This episode dives into the physiology and pathophysiology of pleural disease, as well as a step-wise approach ... Now onto pleural space and fluid…. *Pleural fluid produced from systemic capillaries in parietal pleural surface then absorbed ... CRACKCast E077 - Pleural Disease. In CRACKCast, Podcast by Adam Thomas. May 11, 2017. Leave a Comment ...
Toxic particles can also get into the pleural space and develop into severe diseases. Pleural disease is often a secondary ... and the lasting repercussions this dangerous disease may lead to. Many victims of pleural disease are unable to continue an ... Many victims of pleural disease do not survive more than a few years after an initial diagnosis. It is therefore important to ... The impact of pleural disease will not only impact a workers current situation but will frequently require the worker to quit ...
Pleural Disease and Pneumothorax. July 14, 2011. by CrashMaster for more on hemo/pneumothorax, see the thoracic trauma section ... If disease of pleura, then exudative malignancy or inflammatory.. Increased peritoneal fluid can also cause pleural effusion ... Pleural Effusion. Pleural fluid is secreted by the parietal and absorbed by the visceral pleura capillaries. LHF causes ... Normal hemostasis by vasoconstriction and clot formation may be impeded by lung movement, changes in pleural pressure during ...
This article describes the radiographic and cross-sectional appearances of pleural diseases, which are commonly encountered in ... The conditions covered include benign and malignant pleural thickening, pleural effusions, empyema and pneumothoraces. The ... The presence of a pleural abnormality is usually suggested following a routine chest x-ray, with a number of imaging modalities ... Imaging plays an important role in the diagnosis and subsequent management of patients with pleural disease. ...
Home/Health/What is Pleural Mesothelioma: Understanding the Deadly Disease. What is Pleural Mesothelioma: Understanding the ... In conclusion, pleural mesothelioma is a devastating disease primarily caused by asbestos exposure. Understanding the causes, ... Treatment Options for Pleural Mesothelioma. Surgery. Surgery plays a significant role in the treatment of pleural mesothelioma ... Understanding Pleural Mesothelioma. Causes and Risk Factors. Pleural mesothelioma is primarily caused by prolonged exposure to ...
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Learning Objectives:1.Identify diagnoses and abnormalities of the cardiovascular system, and formulate a treatment plan based on available medical and surgical therapeutic options2. Provide a cross specialty/ multidisciplinary educational approach to play role in patient management.3. Develop teaching and effective presentation skills inform of lectures or discussions of
... J Heart Lung Transplant. 2005 Dec;24(12):2086-90. doi: 10.1016/j. ... The second most common PSP was loculated pleural effusion (21% of PSP). Empyema was uncommon (2 patients, 3% of total patients ... loculated pleural effusions, or empyema in 68 patients for which complete data were available. ... to assess whether size and shape mismatch of the donor organ to the recipient pre-disposes to the development of pleural space ...
Pleural disease. *. You have accessRestricted access. Prospective validation of the RAPID clinical risk prediction score in ... Mild parenchymal lung disease is still lung disease Laurent Godinas, Sergio Harari, Joan A. Barberà, David Montani ... Mild parenchymal lung disease is still lung disease Robin Condliffe, David G. Kiely, Robert A. Lewis ... Pleural diseases and COVID-19: ubi fumus, ibi ignis José M. Porcel ...
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Our pleural disease service provides clinic appointments and procedures at Charing Cross and St Marys hospitals. ... Pleural clinic at St Marys Hospital. Address. Chest and allergy outpatients. Ground floor. Mint Wing. St Marys Hospital. ... Pleural procedures at Charing Cross Hospital. Address. Outpatients department. Fifth floor, north wing. Charing Cross Hospital ... Pleural procedures at St Marys Hospital. Address. Endoscopy. Second floor. Queen Elizabeth the Queen Mother (QEQM) building. ...
Pediatricians should consider the diagnosis of Kawasaki disease in the presence of pneumonia and pleural effusion that is ... It is a multisystem disease; therefore, it may present with non-cardiac findings of disease. Here, we report the case of 7-year ... We also present a literature review on pulmonary involvement due to Kawasaki disease. ... This will prevent delay in diagnosis and the adverse consequences of the disease. ...
General treatment approach Stage I resectable: Patients with operable disease may receive extrapleural pneumonectomy (EPP); if ... Treatment protocols for malignant pleural mesothelioma are provided below, including general approaches and treatment by ... encoded search term (Malignant Pleural Mesothelioma Treatment Protocols) and Malignant Pleural Mesothelioma Treatment Protocols ... Surgery May Worsen Pleural Mesothelioma Survival Outcomes * Court Tosses $223.8 Million Verdict Against J&J in Talc Cancer Case ...
Interstitial Lung Disease (ILD), asthma, and pleural disease are leading causes of morbidity and mortality. We aimed to ... Interstitial Lung Disease (ILD), asthma, and pleural disease are leading causes of morbidity and mortality. We aimed to ... Frailty prevalence and association with clinical outcomes in Interstitial Lung Disease, Asthma, and Pleural Disease.. Alessia ... Frailty prevalence and association with clinical outcomes in Interstitial Lung Disease, Asthma, and Pleural Disease / Verduri, ...
The term lymphoblastic lymphoma (LBL) has been used to describe predominantly lymph node-based disease; however, clinical ... Stage III - Sites on both sides of the diaphragm (mediastinal mass; pleural effusion; unresectable abdominal disease) ... Because radiation is useful both for prophylaxis of CNS disease and treatment of CNS disease, a radiation oncologist should be ... If a pleural effusion is present and aspiration fluid is positive for lymphoma, it may obviate the need for further biopsy. ...

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