Infections with viruses of the genus PNEUMOVIRUS, family PARAMYXOVIRIDAE. This includes RESPIRATORY SYNCYTIAL VIRUS INFECTIONS, an important cause of respiratory disease in humans.
A genus of the family PARAMYXOVIRIDAE (subfamily PNEUMOVIRINAE) where the human and bovine virions have neither hemagglutinin nor neuraminidase activity. RESPIRATORY SYNCYTIAL VIRUS, HUMAN is the type species.
A species of the genus PNEUMOVIRUS causing pneumonia in mice.
Large woodland game BIRDS in the subfamily Meleagridinae, family Phasianidae, order GALLIFORMES. Formerly they were considered a distinct family, Melegrididae.
A genus of the subfamily PNEUMOVIRINAE, containing two members: Turkey rhinotracheitis virus and a human Metapneumovirus. Virions lack HEMAGGLUTININ and NEURAMINIDASE.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Infections with viruses of the family PARAMYXOVIRIDAE. This includes MORBILLIVIRUS INFECTIONS; RESPIROVIRUS INFECTIONS; PNEUMOVIRUS INFECTIONS; HENIPAVIRUS INFECTIONS; AVULAVIRUS INFECTIONS; and RUBULAVIRUS INFECTIONS.
Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.
Inflammation of the lung parenchyma that is caused by a viral infection.
Infection of the lung often accompanied by inflammation.
Inflammation of the lung parenchyma that is caused by bacterial infections.
A species of RESPIROVIRUS also called hemadsorption virus 2 (HA2), which causes laryngotracheitis in humans, especially children.
An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.

Isolation of avian pneumovirus from an outbreak of respiratory illness in Minnesota turkeys. (1/59)

Antibodies to avian pneumovirus (APV) were first detected in Minnesota turkeys in 1997. Virus isolation was attempted on 32 samples (28 tracheal swabs, 4 pools of trachea and turbinates) that were positive for APV by reverse transcriptase polymerase chain reaction (RT-PCR). The cell cultures used were chicken embryo fibroblast (CEF), Vero cells, and QT-35 cells. Five virus isolates were obtained from these samples, and the identity of the isolates was confirmed by RT-PCR. Four isolates were obtained by inoculation of CEF cells, and 1 isolate was obtained in QT-35 cells after 3-7 blind passages in cell cultures. Vero cells did not yield any isolate on primary isolation; however, all 5 isolates could be adapted to grow in Vero cells following primary isolation in CEF or QT-35 cells. This is the first report of isolation of APV in Minnesota and also the first report of primary isolation of APV in QT-35 cells.  (+info)

A modified enzyme-linked immunosorbent assay for the detection of avian pneumovirus antibodies. (2/59)

Avian pneumovirus (APV) infection of turkeys in Minnesota was first confirmed in March 1997. Serum samples (n = 5,194) from 539 submissions to Minnesota Veterinary Diagnostic Laboratory were tested by a modified enzyme-linked immunosorbent assay (ELISA). Of these, 2,528 (48.7%) samples from 269 submissions were positive and 2,666 (51.3%) samples from 270 submissions were negative for APV antibodies. Most positive samples were from Kandiyohi, Stearns, Morrison, and Meeker counties in Minnesota. In addition, 10 samples from South Dakota were positive. The sensitivity and specificity of the ELISA test with anti-chicken and anti-turkey conjugates were compared by testing field and experimental sera. The ELISA test with anti-turkey conjugate was more sensitive than that with anti-chicken conjugate. The ELISA tests with antigens prepared with APV strains isolated from Colorado and Minnesota were also compared. No difference was detectable. Currently, the Minnesota Veterinary Diagnostic Laboratory uses an antigen prepared from the Colorado isolate of APV and a goat anti-turkey conjugate in the ELISA test.  (+info)

The chemokine macrophage-inflammatory protein-1 alpha and its receptor CCR1 control pulmonary inflammation and antiviral host defense in paramyxovirus infection. (3/59)

In this work, we explore the responses of specific gene-deleted mice to infection with the paramyxovirus pneumonia virus of mice (PVM). We have shown previously that infection of wild type mice with PVM results in pulmonary neutrophilia and eosinophilia accompanied by local production of macrophage-inflammatory protein-1 alpha (MIP-1 alpha). Here we examine the role of MIP-1 alpha in the pathogenesis of this disease using mice deficient in MIP-1 alpha or its receptor, CCR1. The inflammatory response to PVM in MIP-1 alpha-deficient mice was minimal, with approximately 10-60 neutrophils/ml and no eosinophils detected in bronchoalveolar lavage fluid. Higher levels of infectious virus were recovered from lung tissue excised from MIP-1 alpha-deficient than from fully competent mice, suggesting that the inflammatory response limits the rate of virus replication in vivo. PVM infection of CCR1-deficient mice was also associated with attenuated inflammation, with enhanced recovery of infectious virus, and with accelerated mortality. These results suggest that the MIP-1 alpha/CCR1-mediated acute inflammatory response protects mice by delaying the lethal sequelae of infection.  (+info)

Development of a highly sensitive and specific enzyme-linked immunosorbent assay based on recombinant matrix protein for detection of avian pneumovirus antibodies. (4/59)

The matrix (M) protein of avian pneumovirus (APV) was evaluated for its antigenicity and reliability in an enzyme-linked immunosorbent assay (ELISA) for diagnosis of APV infection, a newly emergent disease of turkeys in United States. Sera from APV-infected turkeys consistently contained antibodies to a 30-kDa protein (M protein). An ELISA based on recombinant M protein generated in Escherichia coli was compared with the routine APV ELISA that utilizes inactivated virus as antigen. Of 34 experimentally infected turkeys, 33 (97.1%) were positive by M protein ELISA whereas only 18 (52.9%) were positive by routine APV ELISA 28 days after infection. None of the serum samples from 41 uninfected experimental turkeys were positive by M protein ELISA. Of 184 field sera from turkey flocks suspected of having APV infection, 133 (72.3%) were positive by M protein ELISA whereas only 99 (53.8%) were positive by routine APV ELISA. Twelve serum samples, which were negative by M protein ELISA but positive by routine APV ELISA, were not reactive with either recombinant M protein or denatured purified APV proteins by Western analysis. This indicates that the samples had given false-positive results by routine APV ELISA. The M protein ELISA was over six times more sensitive than virus isolation (11.5%) in detecting infections from samples obtained from birds showing clinical signs of APV infection. Taken together, these results show that ELISA based on recombinant M protein is a highly sensitive and specific test for detecting antibodies to APV.  (+info)

Avian pneumovirus (APV) RNA from wild and sentinel birds in the United States has genetic homology with RNA from APV isolates from domestic turkeys. (5/59)

Nasal turbinates or swabs were collected from wild ducks, geese, owls, sparrows, swallows, and starlings and from sentinel ducks placed next to turkey farms experiencing avian pneumovirus (APV) infections and were analyzed for APV genome and infectious particles. APV RNA was detected in samples examined from geese, sparrows, and starlings. APV RNA and antibodies were also detected in two different groups of sentinel ducks. Infectious APV was recovered from sentinel duck samples. The APV M gene isolated from the wild birds had over 96% predicted amino acid identity with APV/Minnesota 2A, which was isolated earlier from domestic turkeys showing respiratory illness, suggesting that wild birds may be involved in spreading APV infection.  (+info)

Immunohistochemical detection of avian pneumovirus in formalin-fixed tissues. (6/59)

An immunohistochemical staining technique (IHC) was developed to detect avian pneumovirus (APV) antigen in formalin-fixed, paraffin-embedded tissue sections using streptavidin-biotin immunoperoxidase staining. Samples of nasal turbinates and infraorbital sinuses were collected from 4-week-old poults experimentally inoculated with APV and from older turkeys infected during naturally occurring outbreaks of avian pneumovirus. Tissue was fixed in 10% buffered neutral formalin, embedded in paraffin, sectioned and stained. Inflammatory changes were observed microscopically in the mucosa and submucosa of the nasal turbinates and infraorbital sinuses of both experimentally inoculated poults and naturally infected birds. Viral antigen was detected by IHC in the ciliated epithelial cells of nasal turbinates and infraorbital sinuses.  (+info)

Detection of antibodies to U.S. isolates of avian pneumovirus by a recombinant nucleocapsid protein-based sandwich enzyme-linked immunosorbent assay. (7/59)

The nucleocapsid (N) protein of subgroup C (United States-specific) avian pneumovirus (APV/US) was expressed in Escherichia coli, and antibodies to the recombinant N protein were shown to specifically recognize the approximately 47-kDa N protein of APV/US by Western immunoblot analysis. The recombinant APV/US N protein was used in a sandwich-capture enzyme-linked immunosorbent assay (ELISA), and the resulting assay was found to be more sensitive and specific than the routine indirect ELISA for the detection of APV/US antibodies in turkey sera.  (+info)

PCR-based detection of an emerging avian pneumovirus in US turkey flocks. (8/59)

Avian pneumovirus (APV) or turkey rhinotracheitis virus (TRTV) is an important respiratory pathogen of domesticated poultry in many countries in Europe, Africa, and Asia. Until recently, the United States was considered free of APV. In late 1996, an atypical upper respiratory tract infection appeared in turkey flocks in Colorado and shortly thereafter in turkey flocks in Minnesota. An avian pneumovirus (APV-US) that was serologically distinct from the previously described TRTV was isolated as the primary cause of the new syndrome. The nucleotide sequence of a fragment of the APV-US fusion gene was determined and used to develop a polymerase chain reaction-based assay that specifically detects APV-US viral nucleic acid sequences in RNA extracts of tracheal swabs and turbinate homogenates. The assay is highly sensitive in that it can detect <0.01 TCID50 of APV. The availability of this assay enables the rapid and accurate determination of APV-US in infected poultry flocks.  (+info)

Pneumovirus infections refer to respiratory illnesses caused by viruses belonging to the Pneumoviridae family, specifically human respirovirus (hRSV) and human metapneumovirus (hMPV). These viruses primarily infect the respiratory tract and can cause a wide range of symptoms, from mild upper respiratory tract infections to severe lower respiratory tract illnesses such as bronchiolitis and pneumonia.

Human respirovirus (hRSV) is a leading cause of bronchiolitis and pneumonia in infants and young children, while human metapneumovirus (hMPV) tends to infect older children and adults, causing similar respiratory symptoms. Both viruses can also cause more severe disease in immunocompromised individuals, the elderly, and those with underlying medical conditions.

Transmission of these viruses typically occurs through close contact with infected individuals or contaminated surfaces, and they are highly contagious. Preventive measures include good hygiene practices, such as frequent handwashing and avoiding close contact with sick individuals. Currently, there are no vaccines available to prevent pneumovirus infections, but antiviral treatments and supportive care can help manage the symptoms and reduce the risk of complications.

Pneumovirus is a genus of viruses in the family Pneumoviridae, order Mononegavirales. It includes several species that can cause respiratory infections in humans and animals. The most well-known species that infect humans is Human Respiratory Syncytial Virus (HRSV), which is a major cause of bronchiolitis and pneumonia in young children, the elderly, and immunocompromised individuals. Other human pneumoviruses include Human Metapneumovirus (HMPV) and Avian Metapneumovirus subtype C (AMPV-C). These viruses can cause similar respiratory symptoms, ranging from mild to severe.

Pneumoviruses are enveloped, negative-sense, single-stranded RNA viruses that replicate in the cytoplasm of infected cells. They have a nonsegmented genome and encode several structural proteins, including an attachment protein, fusion protein, matrix protein, and nucleocapsid protein. The virions are typically pleomorphic, with a diameter of 150-250 nm.

Transmission of pneumoviruses occurs through respiratory droplets or direct contact with contaminated surfaces. Preventive measures include good hygiene practices, such as hand washing and covering the mouth and nose when coughing or sneezing. There are currently no vaccines available for human pneumoviruses, but several candidates are in development. Treatment is primarily supportive and may include oxygen therapy, mechanical ventilation, and antiviral medications in severe cases.

Murine pneumonia virus (MPV) is not a widely recognized or officially established medical term. However, it may refer to the Pneumonia Virus of Mice (PVM), which is a pathogen that affects mice and can cause interstitial pneumonia.

PVM is an enveloped, single-stranded, negative-sense RNA virus belonging to the family Paramyxoviridae and the genus Pneumovirus. It primarily infects laboratory mice but has also been found in wild mouse populations. The virus replicates in the respiratory epithelium, leading to interstitial pneumonia and inflammation of the airways.

It is essential to note that Murine Pneumonia Virus should not be confused with Hantavirus Pulmonary Syndrome (HPS), which is also known as "mouse-related pulmonary syndrome." HPS is a severe, sometimes fatal, respiratory disease in humans caused by exposure to hantaviruses, which are found in rodents.

I'm not aware of any recognized medical term or condition specifically referred to as "turkeys." The term "turkey" is most commonly used in a non-medical context to refer to the large, bird-like domesticated fowl native to North America, scientifically known as Meleagris gallopavo.

However, if you are referring to a medical condition called "turkey neck," it is a colloquial term used to describe sagging or loose skin around the neck area, which can resemble a turkey's wattle. This condition is not a formal medical diagnosis but rather a descriptive term for an aesthetic concern some people may have about their appearance.

If you meant something else by "turkeys," please provide more context so I can give you a more accurate answer.

Metapneumovirus is a type of virus that can cause respiratory infections in humans and animals. The human metapneumovirus (HMPV) is a leading cause of acute respiratory infection (ARI), particularly in young children, the elderly, and people with weakened immune systems. It is associated with a wide range of clinical manifestations, ranging from mild upper respiratory symptoms to severe bronchiolitis and pneumonia.

HMPV is an enveloped, single-stranded RNA virus that belongs to the Pneumoviridae family, subfamily Pneumovirinae, and genus Metapneumovirus. It was first identified in 2001, although it is believed to have been circulating in humans for at least 50 years before its discovery. HMPV is transmitted through respiratory droplets and direct contact with infected individuals or contaminated surfaces.

The incubation period of HMPV ranges from 3 to 6 days, after which symptoms such as cough, fever, nasal congestion, sore throat, and difficulty breathing may appear. In severe cases, HMPV can lead to bronchitis, bronchiolitis, or pneumonia, requiring hospitalization, especially in high-risk populations. Currently, there is no specific antiviral treatment for HMPV infections, and management typically involves supportive care, such as oxygen therapy, hydration, and respiratory support if necessary. Prevention measures include good hand hygiene, wearing masks, and avoiding close contact with infected individuals.

A lung is a pair of spongy, elastic organs in the chest that work together to enable breathing. They are responsible for taking in oxygen and expelling carbon dioxide through the process of respiration. The left lung has two lobes, while the right lung has three lobes. The lungs are protected by the ribcage and are covered by a double-layered membrane called the pleura. The trachea divides into two bronchi, which further divide into smaller bronchioles, leading to millions of tiny air sacs called alveoli, where the exchange of gases occurs.

Paramyxoviridae is a family of viruses that includes several important pathogens causing respiratory infections in humans and animals. According to the medical perspective, Paramyxoviridae infections refer to the diseases caused by these viruses.

Some notable human paramyxovirus infections include:

1. Respiratory Syncytial Virus (RSV) Infection: RSV is a common cause of respiratory tract infections, particularly in young children and older adults. It can lead to bronchiolitis and pneumonia, especially in infants and patients with compromised immune systems.
2. Measles (Rubeola): Measles is a highly contagious viral disease characterized by fever, cough, coryza (runny nose), conjunctivitis, and a maculopapular rash. It can lead to severe complications such as pneumonia, encephalitis, and even death, particularly in malnourished children and individuals with weakened immune systems.
3. Parainfluenza Virus Infection: Parainfluenza viruses are responsible for upper and lower respiratory tract infections, including croup, bronchitis, and pneumonia. They mainly affect young children but can also infect adults, causing mild to severe illnesses.
4. Mumps: Mumps is a contagious viral infection that primarily affects the salivary glands, causing painful swelling. It can lead to complications such as meningitis, encephalitis, deafness, and orchitis (inflammation of the testicles) in rare cases.
5. Human Metapneumovirus (HMPV) Infection: HMPV is a respiratory virus that can cause upper and lower respiratory tract infections, similar to RSV and parainfluenza viruses. It mainly affects young children and older adults, leading to bronchitis, pneumonia, and exacerbations of chronic lung diseases.

Prevention strategies for Paramyxoviridae infections include vaccination programs, practicing good personal hygiene, and implementing infection control measures in healthcare settings.

Poultry diseases refer to a wide range of infectious and non-infectious disorders that affect domesticated birds, particularly those raised for meat, egg, or feather production. These diseases can be caused by various factors including viruses, bacteria, fungi, parasites, genetic predisposition, environmental conditions, and management practices.

Infectious poultry diseases are often highly contagious and can lead to significant economic losses in the poultry industry due to decreased production, increased mortality, and reduced quality of products. Some examples of infectious poultry diseases include avian influenza, Newcastle disease, salmonellosis, colibacillosis, mycoplasmosis, aspergillosis, and coccidiosis.

Non-infectious poultry diseases can be caused by factors such as poor nutrition, environmental stressors, and management issues. Examples of non-infectious poultry diseases include ascites, fatty liver syndrome, sudden death syndrome, and various nutritional deficiencies.

Prevention and control of poultry diseases typically involve a combination of biosecurity measures, vaccination programs, proper nutrition, good management practices, and monitoring for early detection and intervention. Rapid and accurate diagnosis of poultry diseases is crucial to implementing effective treatment and prevention strategies, and can help minimize the impact of disease outbreaks on both individual flocks and the broader poultry industry.

Viral pneumonia is a type of pneumonia caused by viral infection. It primarily affects the upper and lower respiratory tract, leading to inflammation of the alveoli (air sacs) in the lungs. This results in symptoms such as cough, difficulty breathing, fever, fatigue, and chest pain. Common viruses that can cause pneumonia include influenza virus, respiratory syncytial virus (RSV), and adenovirus. Viral pneumonia is often milder than bacterial pneumonia but can still be serious, especially in young children, older adults, and people with weakened immune systems. Treatment typically involves supportive care, such as rest, hydration, and fever reduction, while the body fights off the virus. In some cases, antiviral medications may be used to help manage symptoms and prevent complications.

Pneumonia is an infection or inflammation of the alveoli (tiny air sacs) in one or both lungs. It's often caused by bacteria, viruses, or fungi. Accumulated pus and fluid in these air sacs make it difficult to breathe, which can lead to coughing, chest pain, fever, and difficulty breathing. The severity of symptoms can vary from mild to life-threatening, depending on the underlying cause, the patient's overall health, and age. Pneumonia is typically diagnosed through a combination of physical examination, medical history, and diagnostic tests such as chest X-rays or blood tests. Treatment usually involves antibiotics for bacterial pneumonia, antivirals for viral pneumonia, and supportive care like oxygen therapy, hydration, and rest.

Bacterial pneumonia is a type of lung infection that's caused by bacteria. It can affect people of any age, but it's more common in older adults, young children, and people with certain health conditions or weakened immune systems. The symptoms of bacterial pneumonia can vary, but they often include cough, chest pain, fever, chills, and difficulty breathing.

The most common type of bacteria that causes pneumonia is Streptococcus pneumoniae (pneumococcus). Other types of bacteria that can cause pneumonia include Haemophilus influenzae, Staphylococcus aureus, and Mycoplasma pneumoniae.

Bacterial pneumonia is usually treated with antibiotics, which are medications that kill bacteria. The specific type of antibiotic used will depend on the type of bacteria causing the infection. It's important to take all of the prescribed medication as directed, even if you start feeling better, to ensure that the infection is completely cleared and to prevent the development of antibiotic resistance.

In severe cases of bacterial pneumonia, hospitalization may be necessary for close monitoring and treatment with intravenous antibiotics and other supportive care.

Parainfluenza Virus 1, Human (HPIV-1) is a type of respiratory virus that belongs to the family Paramyxoviridae and genus Respirovirus. It is one of the four serotypes of human parainfluenza viruses (HPIVs), which are important causes of acute respiratory infections in children, immunocompromised individuals, and the elderly.

HPIV-1 primarily infects the upper respiratory tract, causing symptoms such as cough, runny nose, sore throat, and fever. However, it can also cause lower respiratory tract infections, including bronchitis, bronchiolitis, and pneumonia, particularly in young children and infants.

HPIV-1 is transmitted through respiratory droplets or direct contact with infected individuals. The incubation period for HPIV-1 infection ranges from 2 to 7 days, after which symptoms can last for up to 10 days. There is no specific antiviral treatment available for HPIV-1 infections, and management typically involves supportive care such as hydration, fever reduction, and respiratory support if necessary.

Prevention measures include good hand hygiene, avoiding close contact with infected individuals, and practicing cough etiquette. Vaccines are not currently available for HPIV-1 infections, but research is ongoing to develop effective vaccines against these viruses.

Influenza, also known as the flu, is a highly contagious viral infection that attacks the respiratory system of humans. It is caused by influenza viruses A, B, or C and is characterized by the sudden onset of fever, chills, headache, muscle pain, sore throat, cough, runny nose, and fatigue. Influenza can lead to complications such as pneumonia, bronchitis, and ear infections, and can be particularly dangerous for young children, older adults, pregnant women, and people with weakened immune systems or chronic medical conditions. The virus is spread through respiratory droplets produced when an infected person coughs, sneezes, or talks, and can also survive on surfaces for a period of time. Influenza viruses are constantly changing, which makes it necessary to get vaccinated annually to protect against the most recent and prevalent strains.

'Influenza A Virus, H1N1 Subtype' is a specific subtype of the influenza A virus that causes flu in humans and animals. It contains certain proteins called hemagglutinin (H) and neuraminidase (N) on its surface, with this subtype specifically having H1 and N1 antigens. The H1N1 strain is well-known for causing the 2009 swine flu pandemic, which was a global outbreak of flu that resulted in significant morbidity and mortality. This subtype can also cause seasonal flu, although the severity and symptoms may vary. It is important to note that influenza viruses are constantly changing, and new strains or subtypes can emerge over time, requiring regular updates to vaccines to protect against them.

"Respiratory Syncytial Virus Infection (RSV)". Centers for Disease Control and Prevention. Retrieved 2019-06-03. McIntosh, K. M ... Isolating animals and humans that have a pneumovirus is the best way to prevent the virus from spreading. Molecular studies ... Other viruses in this taxon include canine pneumovirus. The genus Orthopneumovirus is included in the family Pneumoviridae. ... The best methods of prevention of orthopneumovirus infection are covering cough and sneezing to prevent transmission of ...
Human metapneumovirus infection is very similar to the common cold; it is an upper respiratory infection. It will typically ... A unique feature of the genome is the M2 gene, which encodes proteins M2-1 and M2-2. The pneumovirus M2-1 protein is ... This specific infection is most common in children, especially under the age of five. Common symptoms include runny nose, ... Respiratory tract infections are associated with member viruses such as human respiratory syncytial virus. There are five ...
... influenza-based defective interfering virus provides protection against pneumovirus infection in vivo" (PDF). Vaccine. 29 (15 ... It is thought that because of their specificity, DIPs will be targeted to sites of infection. In one example, scientists have ... Research has been conducted by virologists to learn more about the interference in infection of host cells and how DI genomes ... Stauffer Thompson KA, Rempala GA, Yin J (April 2009). "Multiple-hit inhibition of infection by defective interfering particles ...
... et al., "Respiratory Syncytial Virus and Human Metapneumovirus in Children with Acute Respiratory Infections ... Tripp, Ralph A. (2010-03-15), "Pneumovirus and Metapneumovirus: Respiratory Syncytial Virus and Human Metapneumovirus", Topley ... 2006 Respiratory Syncytial Virus and Human Metapneumovirus in Children with Acute Respiratory Infections in Yemen - Sept. 2005 ... Andrew Kirby et al., "Rotavirus and Norovirus Infections in Children in Sana'a, Yemen," Tropical Medicine & International ...
So far, peak infection from hMPV in the northern hemisphere is in late winter and early spring, but it can be found globally ... "A newly discovered human pneumovirus isolated from young children with respiratory tract disease". Nature Medicine. 7 (6): 719- ... Hospital-acquired infections with human metapneumovirus have been reported. HMPV has been shown to circulate during fall and ... Despite near universal infection during early life, reinfections are common in older children and adults. Human metapneumovirus ...
In the case of a secondary bacterial infection, antimicrobials may be given. In contrast to human RSV, commercial BRSV vaccines ... Bovine respiratory syncytial virus (BRSV) is pneumovirus closely related to human respiratory syncytial virus (RSV) that is a ... infection with BRSV results in secondary bacterial pneumonia due to interference with the host's immune system and enhancement ... Similarly to other viral infections, treatment of BRSV is typically supportive. Anti-inflammatory drugs may be required to ...
Flocks become quiet after infection. If there is no secondary infection and the flock is in good condition, birds can recover ... Md Zulfekar Ali (2017). Avian Pneumovirus (APV) (Report). doi:10.13140/RG.2.2.22102.65602. Lee, Eun ho; Song, Min-Suk; Shin, ... Even though there is a great homology between hMPV and aMPV-C, no infections of the aMPV-C in humans have been noticed. Also ... Infection with the virus is associated with swollen head syndrome, with swelling peri- and infraorbital sinuses, foamy eyes, ...
... pneumovirus infections MeSH C02.782.580.600.620.750 - respiratory syncytial virus infections MeSH C02.782.580.600.680 - ... cardiovirus infections MeSH C02.782.687.207 - common cold MeSH C02.782.687.359 - enterovirus infections MeSH C02.782.687.359. ... deltaretrovirus infections MeSH C02.782.815.200.260 - enzootic bovine leukosis MeSH C02.782.815.200.470 - htlv-i infections ... avulavirus infections MeSH C02.782.580.600.080.600 - newcastle disease MeSH C02.782.580.600.400 - henipavirus infections MeSH ...
Treatment of bronchiolitis is usually focused on the hydration and symptoms instead of the infection itself since the infection ... This is most commonly caused by respiratory syncytial virus (RSV, also known as human pneumovirus). Other agents that cause ... Respiratory infections were shown to be significantly less common among breastfed infants and fully breastfed RSV-positive ... Infants with bronchiolitis between the age of two and three months have a second infection by bacteria (usually a urinary tract ...
Avian pneumovirus) is a common problem in broiler breeders and occasionally in broilers and layers in Europe and South Africa. ... Avian pneumovirus infections (swollen head syndrome). Occurrence: Europe, South Africa, Middle East, Asia.. Species affected: ... Causes: Pneumovirus is a single-stranded, 80-200nm RNA virus.. Effects: Sneezing and nasal discharge, foamy conjunctivitis, ... Avian pneumovirus is a non-hemagglutinating, nonsegmented, enveloped single stranded RNA virus of the family Paramyxoviridae ...
Avian pneumovirus infection: questions still unanswered. Avian Pathol. 1996;25:639-48. DOIPubMedGoogle Scholar ... We identified infection with subgroup C aMPV infection in local meat-type commercial chickens with variable severe respiratory ... Hamelin ME, Yim K, Kuhn KH, Cragin RP, Boukhvalova M, Blanco JCG, Pathogenesis of human metapneumovirus lung infection in BALB/ ... These observations are similar to those made with hMPV infection in animal models (11,12). However, the exact mechanism needs ...
"Respiratory Syncytial Virus Infection (RSV)". Centers for Disease Control and Prevention. Retrieved 2019-06-03. McIntosh, K. M ... Isolating animals and humans that have a pneumovirus is the best way to prevent the virus from spreading. Molecular studies ... Other viruses in this taxon include canine pneumovirus. The genus Orthopneumovirus is included in the family Pneumoviridae. ... The best methods of prevention of orthopneumovirus infection are covering cough and sneezing to prevent transmission of ...
Infection by influenza virus leads to cell death, especially in the upper airway. When direct viral infection of lung ... A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001 Jun. 7(6):719- ... The infections vary from a mild illness to life-threatening croup, bronchiolitis, or pneumonia. Infection in immunocompromised ... and virus-specific IgE in RSV infection and bradykinin, interleukin (IL)-1, IL-6, and IL-8 in rhinovirus infections. RSV ...
Respiratory Tract Infections - Antibiotic Prescribing. - NICE , 2008. Respiratory tract infection (RTI) is defined as any ... This volume focuses on the biology of pneumovirus and metapneumovirus respiratory virus pathogens. These are all enveloped ... It is intended for use as a reference manual for clinicians caring for persons with or at high risk for TB disease or infection ... Although the most common cause of cough is acute self-limited viral infections, chronic cough has a significant impact on ...
Canine Pneumovirus is a virus that is highly contagious to dogs. The shelter said there are no preventative vaccines for the ... According to the shelter, Strep Zoo is an upper respiratory infection that is prevalent even in healthy animals, and symptoms ... The shelter said extreme overcrowding allowed multiple infections spread through the shelter. It was forced to close for a week ... 30, test results for the dog came back positive for pathogens including Strep Zoo and Canine Pneumovirus. ...
17 Viera MH, Amini S, Huo R, Konda S, Block S, Berman B. Herpes simplex virus and human papillomavirus genital infections: new ... streptococcus pneumovirus, influenza A/B, respiratory syncytial virus (RSV), parainfluenza, legionella, chlamydia, gonorrhea, ... 17 Viera MH, Amini S, Huo R, Konda S, Block S, Berman B. Herpes simplex virus and human papillomavirus genital infections: new ... Disseminated herpesvirus infection. Association with primary genital herpes in pregnancy. JAMA 1976; 235: 2731-2733 ...
Respiratory syncytial virus infection in adults. Clin Microbiol Rev. 2000 Jul. 13(3):371-84. [QxMD MEDLINE Link]. [Full Text]. ... A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001 Jun. 7(6):719- ... Human metapneumovirus infections in young and elderly adults. J Infect Dis. 2003 Mar 1. 187(5):785-90. [QxMD MEDLINE Link]. ... Management of infections caused by respiratory syncytial virus. Scand J Infect Dis. 2001. 33(5):323-8. [QxMD MEDLINE Link]. ...
... human parainfluenza viruses 1-3 and human meta pneumovirus (13). An aliquot of each specimen was stored in liquid nitrogen and ... Incidence of influenza virus-associated severe acute respiratory infection in Damanhour district, Egypt, 2013 ... The International Emerging Infections Program (IEIP) of the United States Centers for Disease Control and Prevention (US-CDC) ... Participants with a history of lower respiratory infection were asked if they had sought medical care for themselves or their ...
... and Human Metapneumovirus Infections - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals ... RSV is an RNA virus, classified as a pneumovirus. Subgroups A and B have been identified. ... Respiratory Syncytial Virus (RSV) and Human Metapneumovirus Infections By Brenda L. Tesini , MD, University of Rochester School ... The most recognizable clinical syndromes are bronchiolitis Bronchiolitis Bronchiolitis is an acute viral infection of the lower ...
infection = PNEUMOVIRUS INFECTIONS. Scope Note. A genus of the family PARAMYXOVIRIDAE (subfamily PNEUMOVIRINAE) where the human ... Pneumovirus Preferred Term Term UI T054196. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1994). ... Pneumovirus Preferred Concept UI. M0027313. Registry Number. txid11245. Scope Note. A genus of the family PARAMYXOVIRIDAE ( ... Pneumovirus [B04.820.480.937.600.670.600] * Murine pneumonia virus [B04.820.480.937.600.670.600.550] ...
Heikkinen T, Österback R, Peltola V, Jartti T, Vainionpää R. Human metapneumovirus infections in children. Emerg Infect Dis [ ... A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001;7(6):719-24. ... Clinical symptoms of HMPV infection may progress to bronchitis or pneumonia and are similar to other viruses that cause upper ... Notes from the Field: Severe Human Metapneumovirus Infections - North Dakota, 2016. MMWR. 2017;66(28):486-8. ...
paramyxoviruses, and pneumovirus infections.. In: Diseases of Poultry. Saif, Y.M., Barnes, ...
Department of Infection and Immunity. Research output: Contribution to journal › Article › Research › peer-review ... title = "Seroprevalence of avian influenza virus, infectious bronchitis virus, reovirus, avian pneumovirus, infectious ... T1 - Seroprevalence of avian influenza virus, infectious bronchitis virus, reovirus, avian pneumovirus, infectious ... Seroprevalence of avian influenza virus, infectious bronchitis virus, reovirus, avian pneumovirus, infectious laryngotracheitis ...
... expression in AECs during murine pneumovirus (PVM) infection and IECs during dextran sulfate sodium (DSS)-induced chronic ... Fourthly, to assess IL-22s function during infection, Moniruzzaman and colleagues treated mice with 20 or 100 ng/g rIL-22 2 d ... Direct evidence linking IL-22s impact on colitis and infection to its effects on EC MHC II expression would be valuable. ... treatment with rIL-22 in the model of pulmonary infection increased the mortality rates and lung pathogenic scores in ...
Infection o Coinfection: infection with HBV and HDV at the same time ▪ Greater likelihood of a more severe acute infection ... Pneumovirus • Rubulavirus o Parainfluenza 2 and 4 • Surface receptors o HN: hemagglutinin-neuraminidase ▪ Specificity of entry ... Neonatal infection • Vaccine is available • Serologic Markers for the Diagnosis of HBV Infection o HBsAg - hepatitis B surface ... CORONAVIRIDAE • Cause 15% of coldlike infections in adults • Higher in children o Some pediatric diarrhea o Targets the GI ...
Avian pneumovirus infection in broiler chicks inoculated with Escherichia coli at different time intervals. Avian Pathology, 30 ... Avian pneumovirus Infections of Turkeys and Chickens. The Veterinary Journal, 160:118-125. https://dx.doi.org/10.1053/tvjl. ... Pathogenesis of avian pneumovirus infection in turkeys. Veterinary Pathology, 39:300-310. https://dx.doi.org/10.1354/vp.39-3- ... Co-infections of chickens with avian influenza virus H9N2 and Moroccan Italy 02 infectious bronchitis virus: Effect on ...
Alexander D (2003). Newcastle disease, other avian paramyxoviruses, and pneumovirus infections. In: Saif Y.M., Barnes H.J., ... Newcastle disease viruses (NDV) are by far the most important pathogen for birds of all types and in most countries infection ... Frequency of Hepatitis D Viral Infection in Chronic Hepatitis B Patients in Pakistan. Samia Afzal, Jahanzaib Ahmad, Iram Amin, ... In most countries, use of live vaccines is almost universal exacerbation of infections with viruses of low virulence may mimic ...
Newcastle disease, other avian paramyxoviruses, and pneumovirus infections. In: Saif YM (ed) Disease of Poultry, 7th ed. Iowa ...
Paramyxoviridae Infections(2). * Pneumovirus Infections(2). * Respiratory Syncytial Virus (rsv) Infections (2) ... This report provides top line data relating to the clinical trials on Respiratory Syncytial Virus (RSV) Infections. Report ... Respiratory Syncytial Virus (RSV) Infections Clinical Trial Analysis by Phase, Trial Status, End Point, Sponsor Type and Region ... GlobalDatas clinical trial report, "Respiratory Syncytial Virus (RSV) Infections Clinical Trial Analysis by Trial Phase, Trial ...
Therefore, we evaluated the effect of protease inhibitors on RSV infection. To measure the sensitivity of RSV infection to ... RSV infection can be inhibited by broad serine protease inhibitors, AEBSF and TPCK. We confirmed that AEBSF inhibition is ... Of all the inhibitors tested, AEBSF and TPCK significantly decreased RSV infection. To ascertain that the observed effect of ... To gain insight into the mechanism of this inhibition, AEBSF treatment was applied during different phases of an infection ...
Three animal viruses; transmissible gastroenteritis virus (TGEV), avian pneumovirus (APV), and fowlpox virus were chosen as ... Bacterial-infections; Biological-effects; Cell-biology; Demographic-characteristics; Engineering; Engineering-controls; ...
Human metapneumovirus (HMPV) is a pneumovirus that may cause severe respiratory disease in humans. HMPV infection has been ... RESULTS: HMPV infection (13.3%) was the most predominant infection among the different viral infections in children with ARIs ... After excluding cases of co-infection, we found that PIV-2 infection was associated with upper respiratory tract infections, ... Severe infections were associated with pre-existing underlying diseases and co-infections, but not with PIV serotype. ...
HMPV can independently cause acute lower respiratory tract infection in young children, while all patients showed mild clinical ... All results presented here improve our understanding of clinical characteristics and molecular epidemiology of HMPV infection ... collected respiratory tract samples from children who were hospitalized with acute lower respiratory tract infection in six ... infection is one of the leading causes of hospitalization in young children with acute respiratory illness. In this study, we ...
... transient infections and even death due to NDV infection. These differences may in part result from the host innate immune ... To better understand the host innate immune response to NDV infection in avian species, by using the quantitative real-time ... However, whereas ducks are generally asymptomatic or exhibit only mild symptoms following NDV infection and are thus regarded ... were also greater in CEFs than in DEFs in response to infection to both viruses or treatment with poly(I:C). However, unlike ...
... to initiate infection. The interaction of RSV with ... Lower respiratory tract infections, Pneumonia, Pneumovirus, ... The interaction of RSV with HSPGs thus presents an attractive target for the development of novel inhibitors of RSV infection. ... SB105-A10 prevented RSV infection when added before the viral inoculum, in line with its proposed HSPG-binding mechanism of ... Respiratory syncytial virus (RSV) interacts with cell surface heparan sulphate proteoglycans (HSPGs) to initiate infection. ...
... heterologous immunity and protection against lethal pneumovirus infection. As the defendants would not be able to have a fair ... There are different ways in which microbicides act to prevent infection with genital pathogens. Criteria Individuals authorized ... infections halo infinite script free dry sockets. This was his fourth Arctic expedition, his third as commander. Jamie was ...
Infection by influenza virus leads to cell death, especially in the upper airway. When direct viral infection of lung ... A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001 Jun. 7(6):719- ... The infections vary from a mild illness to life-threatening croup, bronchiolitis, or pneumonia. Infection in immunocompromised ... and measles virus are reported as etiologic agents in severe lower respiratory tract infection. The infection may result in ...
... in Human pneumovirus infections. Pathogens 2 (2013). ... During infection it primarily localizes to the lipid-raft ... Protective immunity against hRSV re-infection is usually suboptimal, however, and recurrent infections are common throughout ... During the course of hRSV infection, the expansion of CD8+ T cells is greater than that of CD4+ T cells and is accompanied by ... In a murine model of hRSV infection, CD4+ T cell production of IL-9, IL-13, and IL-17 contribute to hRSV-induced disease [33]. ...
Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection. J. Immunol. 2019;202:871-882. doi: 10.4049/jimmunol.1800927. [ ... Evidence for gastrointestinal infection of SARS-CoV-2. medRxiv. 2020 doi: 10.1053/j.gastro.2020.02.055. [PMC free article] [ ... Hemilä H. Vitamin C and Infections. Nutrients. 2017;9:339. doi: 10.3390/nu9040339. [PMC free article] [PubMed] [CrossRef] [ ... Hemilä H., Douglas R.M. Vitamin C and acute respiratory infections. Int. J. Tuberc. Lung Dis. 1999;3:756-761. [PubMed] [Google ...

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