An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)
A species of ENTEROVIRUS which is the causal agent of POLIOMYELITIS in humans. Three serotypes (strains) exist. Transmission is by the fecal-oral route, pharyngeal secretions, or mechanical vector (flies). Vaccines with both inactivated and live attenuated virus have proven effective in immunizing against the infection.
A suspension of formalin-inactivated poliovirus grown in monkey kidney cell tissue culture and used to prevent POLIOMYELITIS.
Vaccines used to prevent POLIOMYELITIS. They include inactivated (POLIOVIRUS VACCINE, INACTIVATED) and oral vaccines (POLIOVIRUS VACCINE, ORAL).
A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80)
A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.
Organized services to administer immunization procedures in the prevention of various diseases. The programs are made available over a wide range of sites: schools, hospitals, public health agencies, voluntary health agencies, etc. They are administered to an equally wide range of population groups or on various administrative levels: community, municipal, state, national, international.
I'm sorry for any confusion, but "Afghanistan" is not a medical term and does not have a medical definition. It is a country located in South-Central Asia. If you have any questions related to medical terminology or health concerns, I would be happy to help answer those!
A republic in southern Africa, southwest of DEMOCRATIC REPUBLIC OF THE CONGO and west of ZAMBIA. Its capital is Luanda.
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.
Termination of all transmission of infection by global extermination of the infectious agent through surveillance and containment (From Porta, A Dictionary of Epidemiology, 5th ed).
Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
Schedule giving optimum times usually for primary and/or secondary immunization.
A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.
The geographical area of Asia comprising KAZAKHSTAN; KYRGYZSTAN; TAJIKISTAN; TURKMENISTAN; and UZBEKISTAN. The desert region of Kara Kum (Qara Qum) is largely in Turkmenistan and the desert region of Kyzyl Kum (Kizil Kum or Qizil Qum), is in Uzbekistan and Kazakhstan. (From Webster's New Geographical Dictionary, 1988, p233, 590, 636)
Sudden increase in the incidence of a disease. The concept includes EPIDEMICS and PANDEMICS.
The MEDITERRANEAN SEA, the MEDITERRANEAN ISLANDS, and the countries bordering on the sea collectively.
A genus of the family PICORNAVIRIDAE whose members preferentially inhabit the intestinal tract of a variety of hosts. The genus contains many species. Newly described members of human enteroviruses are assigned continuous numbers with the species designated "human enterovirus".
A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.
A form of paralytic poliomyelitis affecting neurons of the MEDULLA OBLONGATA of the brain stem. Clinical features include impaired respiration, HYPERTENSION, alterations of vasomotor control, and dysphagia. Weakness and atrophy of the limbs and trunk due to spinal cord involvement is usually associated. (From Adams et al., Principles of Neurology, 6th ed, p765)
The formaldehyde-inactivated toxin of Corynebacterium diphtheriae. It is generally used in mixtures with TETANUS TOXOID and PERTUSSIS VACCINE; (DTP); or with tetanus toxoid alone (DT for pediatric use and Td, which contains 5- to 10-fold less diphtheria toxoid, for other use). Diphtheria toxoid is used for the prevention of diphtheria; DIPHTHERIA ANTITOXIN is for treatment.
The general name for NORTH AMERICA; CENTRAL AMERICA; and SOUTH AMERICA unspecified or combined.
The concept pertaining to the health status of inhabitants of the world.
I'm sorry for any confusion, but "Albania" is not a medical term and does not have a medical definition. It is a country located in Southeastern Europe, known for its rich history, diverse culture, and beautiful landscapes. If you have any questions related to medical terminology or health-related topics, I would be happy to help answer them!
I'm sorry for any confusion, but "Pakistan" is a country located in South Asia and it does not have a medical definition. If you have any medical question or term that you would like me to define, please provide it and I will be happy to help.
I'm sorry for any confusion, but "Tajikistan" is not a medical term and does not have a medical definition; it is the name of a country located in Central Asia, officially known as the Republic of Tajikistan.
I'm sorry for any confusion, but "India" is not a medical term that can be defined in a medical context. It is a geographical location, referring to the Republic of India, a country in South Asia. If you have any questions related to medical topics or definitions, I would be happy to help with those!
The geographical area of Asia comprising BORNEO; BRUNEI; CAMBODIA; INDONESIA; LAOS; MALAYSIA; the MEKONG VALLEY; MYANMAR (formerly Burma), the PHILIPPINES; SINGAPORE; THAILAND; and VIETNAM.
A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.
Somalia is located on the east coast of Africa on and north of the Equator and, with Ethiopia, Eritrea, Djibouti, and Kenya, is often referred to as the Horn of Africa. It comprises Italy's former Trust Territory of Somalia and the former British Protectorate of Somaliland. The capital is Mogadishu.
Wooden or metal staffs designed to aid a person in walking. (UMDNS,1999)
A species ARTERIVIRUS, occurring in a number of transplantable mouse tumors. Infected mice have permanently elevated serum levels of lactate dehydrogenase.
A species of ENTEROVIRUS infecting humans and containing 11 serotypes, all coxsackieviruses.
WHO regional office for the Americas acting as a coordinating agency for the improvement of health conditions in the hemisphere. The four main functions are: control or eradication of communicable diseases, strengthening of national and local health services, education and training, and research.
Created as a republic in 1918 by Czechs and Slovaks from territories formerly part of the Austro-Hungarian Empire. The country split into the Czech Republic and Slovakia 1 January 1993.
A vaccine consisting of DIPHTHERIA TOXOID; TETANUS TOXOID; and whole-cell PERTUSSIS VACCINE. The vaccine protects against diphtheria, tetanus, and whooping cough.
Immunoglobulins produced in response to VIRAL ANTIGENS.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
A country in northeastern Africa. The capital is Khartoum.
The geographical area of Africa comprising ANGOLA; BOTSWANA; LESOTHO; MALAWI; MOZAMBIQUE; NAMIBIA; SOUTH AFRICA; SWAZILAND; ZAMBIA; and ZIMBABWE.

ENTEROVIRAL SYNDROMES IN TORONTO, 1964. (1/2)

Virological or serological investigations of 72 children in Toronto and environs, who were hospitalized between January and October 1964 with a variety of syndromes, revealed evidence of enteroviral infection in 29 subjects. Coxsackie B2 was the dominant enterovirus, being isolated from feces and/or cerebrospinal fluid (CSF) of three children with aseptic meningitis, three with pleurodynia, one with myalgia and one with pericarditis; four additional patients showed rising antibody titres to this virus. Coxsackie B1 virus, which has not been isolated in Toronto since 1950, was recovered from feces of three patients with pleurodynia, CSF of one patient with myalgia, and peritoneal fluid of a child with primary peritonitis; one patient with pericarditis showed a rising antibody titre to Coxsackie B1 virus. Coxsackie B3, B4 and Echo 23 viruses were associated with one case each of pleurodynia. Coxsackie B5 virus infected five patients with aseptic meningitis, and one each with pericarditis and myocarditis.  (+info)

Dysphagia in patients with the post-polio syndrome. (2/2)

BACKGROUND AND METHODS: Dysphagia may develop in some patients many years after an attack of acute paralytic poliomyelitis. To identify clinical or subclinical signs of oropharyngeal dysfunction, we examined 32 patients (mean age, 48.9 years) with the post-polio syndrome (defined by new weakness in the limbs). Of the 32 patients, 14 had symptoms of new swallowing difficulties, and 18 were asymptomatic in this respect; 12 had a history of bulbar involvement during acute poliomyelitis. Swallowing function was assessed objectively by ultrasonography, videofluoroscopy, and an oral motor index score for 10 components of oral function. RESULTS: All but 1 of the 32 patients, regardless of whether they had new symptoms or previous bulbar involvement, had some abnormality on detailed testing of oropharyngeal function; only 2 patients had any signs of aspiration. The mean oral motor index score (a quantitative measure of oral sensorimotor function) in the patients was higher than that in age-matched normal subjects (P less than 0.001). Videofluoroscopy showed abnormalities of varying severity, including unilateral bolus transport through the pharynx, pooling in the valleculae or pyriform sinuses, delayed pharyngeal constriction, and impaired tongue movements. On ultrasonography, the mean (+/- SD) duration of wet swallows was significantly longer in the symptomatic patients than in the asymptomatic patients (2.67 +/- 0.70 vs. 1.65 +/- 0.42 seconds). The four patients who were reexamined two years later had objective signs of worsening oropharyngeal function and corresponding new symptoms. CONCLUSIONS: In patients with the post-polio syndrome, the bulbar muscles often have clinical or subclinical signs of dysfunction. These abnormalities suggest that in bulbar neurons there is a slowly progressive deterioration similar to that in the muscles of the limbs.  (+info)

Poliomyelitis, also known as polio, is a highly infectious disease caused by a virus that invades the body through the mouth, usually from contaminated water or food. The virus multiplies in the intestine and can invade the nervous system, causing paralysis.

The medical definition of Poliomyelitis includes:

1. An acute viral infection caused by the poliovirus.
2. Characterized by inflammation of the gray matter of the spinal cord (poliomyelitis), leading to muscle weakness, and in some cases, paralysis.
3. The disease primarily affects children under 5 years of age.
4. Transmission occurs through the fecal-oral route or, less frequently, by respiratory droplets.
5. The virus enters the body via the mouth, multiplies in the intestines, and can invade the nervous system.
6. There are three types of poliovirus (types 1, 2, and 3), each capable of causing paralytic polio.
7. Infection with one type does not provide immunity to the other two types.
8. The disease has no cure, but vaccination can prevent it.
9. Two types of vaccines are available: inactivated poliovirus vaccine (IPV) and oral poliovirus vaccine (OPV).
10. Rare complications of OPV include vaccine-associated paralytic polio (VAPP) and circulating vaccine-derived polioviruses (cVDPVs).

Poliovirus Vaccine, Oral (OPV) is a vaccine used to prevent poliomyelitis (polio). It contains live attenuated (weakened) polioviruses, which stimulate an immune response in the body and provide protection against all three types of wild, infectious polioviruses. OPV is given by mouth, usually in drops, and it replicates in the gastrointestinal tract, where it induces a strong immune response. This response not only protects the individual who receives the vaccine but also helps to stop the spread of poliovirus in the community, providing indirect protection (herd immunity) to those who are not vaccinated. OPV is safe, effective, and easy to administer, making it an important tool for global polio eradication efforts. However, due to the risk of vaccine-associated paralytic polio (VAPP), inactivated poliovirus vaccine (IPV) is recommended for routine immunization in some countries.

Poliovirus is a human enterovirus, specifically a type of picornavirus, that is the causative agent of poliomyelitis (polio). It is a small, non-enveloped, single-stranded, positive-sense RNA virus. There are three serotypes of Poliovirus (types 1, 2 and 3) which can cause different degrees of severity in the disease. The virus primarily spreads through the fecal-oral route and infects the gastrointestinal tract, from where it can invade the nervous system and cause paralysis.

The Poliovirus has an icosahedral symmetry, with a diameter of about 30 nanometers. It contains a single stranded RNA genome which is encapsidated in a protein shell called capsid. The capsid is made up of 60 units of four different proteins (VP1, VP2, VP3 and VP4).

Poliovirus has been eradicated from most countries of the world through widespread vaccination with inactivated poliovirus vaccine (IPV) or oral poliovirus vaccine (OPV). However, it still remains endemic in a few countries and is considered a major public health concern.

Poliovirus Vaccine, Inactivated (IPV) is a vaccine used to prevent poliomyelitis (polio), a highly infectious disease caused by the poliovirus. IPV contains inactivated (killed) polioviruses of all three poliovirus types. It works by stimulating an immune response in the body, but because the viruses are inactivated, they cannot cause polio. After vaccination, the immune system recognizes and responds to the inactivated viruses, producing antibodies that protect against future infection with wild, or naturally occurring, polioviruses. IPV is typically given as an injection in the leg or arm, and a series of doses are required for full protection. It is a safe and effective way to prevent polio and its complications.

Poliovirus vaccines are preparations used for active immunization against poliomyelitis, a highly infectious disease caused by the poliovirus. The two types of poliovirus vaccines available are:

1. Inactivated Poliovirus Vaccine (IPV): This vaccine contains inactivated (killed) poliovirus strains of all three serotypes. IPV is typically administered through an injection, usually in combination with other vaccines. It provides a strong immune response and does not carry the risk of vaccine-associated paralytic polio (VAPP), which is a rare but serious adverse event associated with the oral poliovirus vaccine (OPV).

2. Oral Poliovirus Vaccine (OPV): This vaccine contains live attenuated (weakened) poliovirus strains of all three serotypes. OPV is administered orally and induces both humoral and intestinal immunity, which helps prevent the spread of the virus in a community. However, there is a small risk of VAPP associated with this vaccine, especially after multiple doses. In rare cases, the weakened virus can revert to its virulent form and cause paralytic polio in the vaccinated individual or their close contacts.

Both IPV and OPV have been instrumental in global efforts to eradicate polio. The World Health Organization (WHO) recommends using IPV in routine immunization programs, while using OPV during supplementary immunization activities in areas with a high risk of poliovirus transmission.

Post-poliomyelitis syndrome (PPS) is a condition that affects polio survivors years after recovery from the initial acute poliomyelitis infection. The symptoms of PPS include new onset weakness, fatigue, and pain in the muscles that were previously affected by the poliovirus. These symptoms can occur gradually or suddenly, and they may be worsened by exercise or other physical stressors.

PPS is thought to be caused by ongoing degeneration of the enlarged motor neurons that survived the initial polio infection. It is estimated that up to 50% of polio survivors may experience symptoms of PPS. While there is no cure for PPS, treatment typically focuses on managing symptoms and maintaining function through physical therapy, assistive devices, and pain management strategies.

Paralysis is a loss of muscle function in part or all of your body. It can be localized, affecting only one specific area, or generalized, impacting multiple areas or even the entire body. Paralysis often occurs when something goes wrong with the way messages pass between your brain and muscles. In most cases, paralysis is caused by damage to the nervous system, especially the spinal cord. Other causes include stroke, trauma, infections, and various neurological disorders.

It's important to note that paralysis doesn't always mean a total loss of movement or feeling. Sometimes, it may just cause weakness or numbness in the affected area. The severity and extent of paralysis depend on the underlying cause and the location of the damage in the nervous system.

Muscle hypotonia, also known as decreased muscle tone, refers to a condition where the muscles appear to be flaccid or lacking in tension and stiffness. This results in reduced resistance to passive movements, making the limbs feel "floppy" or "like a rag doll." It can affect any muscle group in the body and can be caused by various medical conditions, including neurological disorders, genetic diseases, and injuries to the nervous system. Hypotonia should not be confused with muscle weakness, which refers to the inability to generate normal muscle strength.

Immunization programs, also known as vaccination programs, are organized efforts to administer vaccines to populations or communities in order to protect individuals from vaccine-preventable diseases. These programs are typically implemented by public health agencies and involve the planning, coordination, and delivery of immunizations to ensure that a high percentage of people are protected against specific infectious diseases.

Immunization programs may target specific age groups, such as infants and young children, or populations at higher risk of certain diseases, such as travelers, healthcare workers, or individuals with weakened immune systems. The goals of immunization programs include controlling and eliminating vaccine-preventable diseases, reducing the morbidity and mortality associated with these diseases, and protecting vulnerable populations from outbreaks and epidemics.

Immunization programs may be delivered through a variety of settings, including healthcare facilities, schools, community centers, and mobile clinics. They often involve partnerships between government agencies, healthcare providers, non-governmental organizations, and communities to ensure that vaccines are accessible, affordable, and acceptable to the populations they serve. Effective immunization programs require strong leadership, adequate funding, robust data systems, and ongoing monitoring and evaluation to assess their impact and identify areas for improvement.

'Afghanistan' is a country and not a medical term or condition. It is located in Central Asia and is bordered by Pakistan, Iran, Turkmenistan, Uzbekistan, Tajikistan, China, and the Arabian Sea. The country has a complex history with ongoing political and security challenges. If you are looking for information related to medical tourism or healthcare in Afghanistan, I can provide some general insights. However, please note that the medical facilities and services in Afghanistan may not be comparable to those in developed countries due to various factors such as infrastructure, resources, and expertise.

I'm not aware of any medical definitions associated with the term "Angola." Angola is a country located in Southern Africa, known officially as the Republic of Angola. It does not have any specific relevance to medical terminology or healthcare. If you have more context or information about why you are looking for a medical definition of Angola, I may be able to provide a more helpful response.

Vaccination is a simple, safe, and effective way to protect people against harmful diseases, before they come into contact with them. It uses your body's natural defenses to build protection to specific infections and makes your immune system stronger.

A vaccination usually contains a small, harmless piece of a virus or bacteria (or toxins produced by these germs) that has been made inactive or weakened so it won't cause the disease itself. This piece of the germ is known as an antigen. When the vaccine is introduced into the body, the immune system recognizes the antigen as foreign and produces antibodies to fight it.

If a person then comes into contact with the actual disease-causing germ, their immune system will recognize it and immediately produce antibodies to destroy it. The person is therefore protected against that disease. This is known as active immunity.

Vaccinations are important for both individual and public health. They prevent the spread of contagious diseases and protect vulnerable members of the population, such as young children, the elderly, and people with weakened immune systems who cannot be vaccinated or for whom vaccination is not effective.

Disease eradication is the complete and permanent elimination of a specific disease from all humans or animals worldwide. This is achieved through various methods, including vaccination programs, improved sanitation, and public health measures. The disease is no longer present in any form, and there is no risk of it re-emerging. Smallpox is the only human disease to have been successfully eradicated so far. Efforts are currently underway to eradicate polio, with significant progress made but still ongoing.

Population surveillance in a public health and medical context refers to the ongoing, systematic collection, analysis, interpretation, and dissemination of health-related data for a defined population over time. It aims to monitor the health status, identify emerging health threats or trends, and evaluate the impact of interventions within that population. This information is used to inform public health policy, prioritize healthcare resources, and guide disease prevention and control efforts. Population surveillance can involve various data sources, such as vital records, disease registries, surveys, and electronic health records.

An immunization schedule is a series of planned dates when a person, usually a child, should receive specific vaccines in order to be fully protected against certain preventable diseases. The schedule is developed based on scientific research and recommendations from health organizations such as the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC).

The immunization schedule outlines which vaccines are recommended, the number of doses required, the age at which each dose should be given, and the minimum amount of time that must pass between doses. The schedule may vary depending on factors such as the individual's age, health status, and travel plans.

Immunization schedules are important for ensuring that individuals receive timely protection against vaccine-preventable diseases, and for maintaining high levels of immunity in populations, which helps to prevent the spread of disease. It is important to follow the recommended immunization schedule as closely as possible to ensure optimal protection.

Tetanus is a serious bacterial infection caused by the bacterium Clostridium tetani. The bacteria are found in soil, dust and manure and can enter the body through wounds, cuts or abrasions, particularly if they're not cleaned properly. The bacterium produces a toxin that affects the nervous system, causing muscle stiffness and spasms, often beginning in the jaw and face (lockjaw) and then spreading to the rest of the body.

Tetanus can be prevented through vaccination, and it's important to get vaccinated if you haven't already or if your immunization status is not up-to-date. If tetanus is suspected, medical attention should be sought immediately, as it can be a life-threatening condition if left untreated. Treatment typically involves administering tetanus immune globulin (TIG) to neutralize the toxin and antibiotics to kill the bacteria, as well as supportive care such as wound cleaning and management, and in some cases, mechanical ventilation may be necessary to assist with breathing.

Central Asia is a geographical region in Asia that stretches from the Caspian Sea in the west to China in the east, and from Russia in the north to Afghanistan in the south. It includes the former Soviet republics of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan.

The medical definition of Central Asia may refer to the epidemiology, healthcare systems, or health issues specific to this region. For example, Central Asia has a high prevalence of infectious diseases such as tuberculosis, hepatitis, and HIV/AIDS, due to various factors including poverty, lack of access to healthcare, and mobility of populations. In addition, non-communicable diseases such as cardiovascular disease, cancer, and diabetes are also becoming more prevalent in Central Asia, partly due to lifestyle changes such as unhealthy diets, physical inactivity, and tobacco use.

Overall, the medical definition of Central Asia encompasses the unique health challenges and healthcare systems that exist within this geographical region.

A disease outbreak is defined as the occurrence of cases of a disease in excess of what would normally be expected in a given time and place. It may affect a small and localized group or a large number of people spread over a wide area, even internationally. An outbreak may be caused by a new agent, a change in the agent's virulence or host susceptibility, or an increase in the size or density of the host population.

Outbreaks can have significant public health and economic impacts, and require prompt investigation and control measures to prevent further spread of the disease. The investigation typically involves identifying the source of the outbreak, determining the mode of transmission, and implementing measures to interrupt the chain of infection. This may include vaccination, isolation or quarantine, and education of the public about the risks and prevention strategies.

Examples of disease outbreaks include foodborne illnesses linked to contaminated food or water, respiratory infections spread through coughing and sneezing, and mosquito-borne diseases such as Zika virus and West Nile virus. Outbreaks can also occur in healthcare settings, such as hospitals and nursing homes, where vulnerable populations may be at increased risk of infection.

I'm sorry for any confusion, but "Mediterranean Region" is not a term with a specific medical definition. The Mediterranean Region typically refers to the geographical area surrounding the Mediterranean Sea, including countries in Southern Europe, North Africa, and Western Asia. However, in a medical context, it might refer to the study of diseases or health characteristics typical of certain populations in this region. For example, the "Mediterranean diet" is a popular term in nutrition and medicine, referring to the traditional eating habits in Mediterranean countries, which are associated with numerous health benefits. If you're looking for medical information related to a specific aspect of the Mediterranean Region or its population, please provide more context so I can give you a more accurate response.

An enterovirus is a type of virus that primarily infects the gastrointestinal tract. There are over 100 different types of enteroviruses, including polioviruses, coxsackieviruses, echoviruses, and newer enteroviruses such as EV-D68 and EV-A71. These viruses are typically spread through close contact with an infected person, or by consuming food or water contaminated with the virus.

While many people infected with enteroviruses may not experience any symptoms, some may develop mild to severe illnesses such as hand, foot and mouth disease, herpangina, meningitis, encephalitis, myocarditis, and paralysis (in case of poliovirus). Infection can occur in people of all ages, but young children are more susceptible to infection and severe illness.

Prevention measures include practicing good hygiene, such as washing hands frequently with soap and water, avoiding close contact with sick individuals, and not sharing food or drinks with someone who is ill. There are also vaccines available to prevent poliovirus infection.

Diphtheria is a serious bacterial infection caused by Corynebacterium diphtheriae. It typically affects the respiratory system, including the nose, throat, and windpipe (trachea), causing a thick gray or white membrane to form over the lining of these areas. This can lead to breathing difficulties, heart complications, and neurological problems if left untreated.

The bacteria can also produce a powerful toxin that can cause damage to other organs in the body. Diphtheria is usually spread through respiratory droplets from an infected person's cough or sneeze, or by contact with contaminated objects or surfaces. The disease is preventable through vaccination.

Poliomyelitis, bulbar: A form of poliomyelitis (polio) caused by the poliovirus, which affects the bulbar region of the brain. The bulbar region is responsible for controlling vital functions such as breathing, swallowing, and speaking. In bulbar polio, the virus attacks the nerves in this area, leading to inflammation and damage. This can result in severe symptoms, including paralysis of the muscles used for breathing, swallowing, and talking. In some cases, bulbar polio can be fatal due to respiratory failure or other complications. Fortunately, polio is now a vaccine-preventable disease, and widespread vaccination campaigns have led to its near-eradication in many parts of the world.

Diphtheria toxoid is a modified form of the diphtheria toxin that has been made harmless but still stimulates an immune response. It is used in vaccines to provide immunity against diphtheria, a serious bacterial infection that can cause breathing difficulties, heart failure, and paralysis. The toxoid is typically combined with other components in a vaccine, such as tetanus toxoid and pertussis vaccine, to form a combination vaccine that protects against multiple diseases.

The diphtheria toxoid is made by treating the diphtheria toxin with formaldehyde, which modifies the toxin's structure and makes it nontoxic while still retaining its ability to stimulate an immune response. When the toxoid is introduced into the body through vaccination, the immune system recognizes it as a foreign substance and produces antibodies against it. These antibodies then provide protection against future infections with the diphtheria bacteria.

The diphtheria toxoid vaccine is usually given as part of a routine childhood immunization schedule, starting at 2 months of age. Booster shots are recommended throughout childhood and adolescence, and adults may also need booster shots if they have not received them previously or if their immune status has changed.

The "Americas" is a term used to refer to the combined landmasses of North America and South America, which are separated by the Isthmus of Panama. The Americas also include numerous islands in the Caribbean Sea, Atlantic Ocean, and Pacific Ocean. This region is home to a diverse range of cultures, ecosystems, and historical sites. It is named after the Italian explorer Amerigo Vespucci, who was one of the first Europeans to explore and map parts of South America in the late 15th century.

"World Health" is not a term that has a specific medical definition. However, it is often used in the context of global health, which can be defined as:

"The area of study, research and practice that places a priority on improving health and achieving equity in health for all people worldwide. It emphasizes trans-national health issues, determinants, and solutions; involves many disciplines within and beyond the health sciences and engages stakeholders from across sectors and societies." (World Health Organization)

Therefore, "world health" could refer to the overall health status and health challenges faced by populations around the world. It encompasses a broad range of factors that affect the health of individuals and communities, including social, economic, environmental, and political determinants. The World Health Organization (WHO) plays a key role in monitoring and promoting global health, setting international standards and guidelines, and coordinating responses to global health emergencies.

I'm sorry for any confusion, but the term "Albania" does not have a medical definition. Albania is a country located in southeastern Europe, known officially as the Republic of Albania. It is bordered by Montenegro to the northwest, Kosovo to the northeast, North Macedonia to the east, and Greece to the south and southeast. Its capital and largest city is Tirana. If you have any questions about medical topics or definitions, I'd be happy to try to help answer them for you!

I'm sorry for any confusion, but "Pakistan" is a country in South Asia and not a medical term or condition. If you have any medical questions or terms you would like defined, I would be happy to help!

I'm sorry for any confusion, but "Tajikistan" is not a medical term. It is the name of a country located in Central Asia. Tajikistan is a sovereign state, bordered by Afghanistan to the south, Uzbekistan to the west, Kyrgyzstan to the north, and China to the east. The capital city of Tajikistan is Dushanbe. If you have any questions about medical topics or terminology, I would be happy to help answer those for you.

I'm sorry for any confusion, but "India" is not a medical term or concept. It is a country in South Asia, the second-most populous country in the world, known for its rich history, diverse culture, and numerous contributions to various fields including medicine. If you have any questions related to medical topics, I would be happy to help answer them!

Southeast Asia is a geographical region that consists of the countries that are located at the southeastern part of the Asian continent. The definition of which countries comprise Southeast Asia may vary, but it generally includes the following 11 countries:

* Brunei
* Cambodia
* East Timor (Timor-Leste)
* Indonesia
* Laos
* Malaysia
* Myanmar (Burma)
* Philippines
* Singapore
* Thailand
* Vietnam

Southeast Asia is known for its rich cultural diversity, with influences from Hinduism, Buddhism, Islam, and Christianity. The region is also home to a diverse range of ecosystems, including rainforests, coral reefs, and mountain ranges. In recent years, Southeast Asia has experienced significant economic growth and development, but the region still faces challenges related to poverty, political instability, and environmental degradation.

The World Health Organization (WHO) is not a medical condition or term, but rather a specialized agency of the United Nations responsible for international public health. Here's a brief description:

The World Health Organization (WHO) is a specialized agency of the United Nations that acts as the global authority on public health issues. Established in 1948, WHO's primary role is to coordinate and collaborate with its member states to promote health, prevent diseases, and ensure universal access to healthcare services. WHO is headquartered in Geneva, Switzerland, and has regional offices around the world. It plays a crucial role in setting global health standards, monitoring disease outbreaks, and providing guidance on various public health concerns, including infectious diseases, non-communicable diseases, mental health, environmental health, and maternal, newborn, child, and adolescent health.

I'm sorry for any confusion, but "Somalia" is not a medical term. It is a country located in the Horn of Africa. If you have any questions about medical terms or health-related topics, I would be happy to try and help answer them for you.

Crutches are medical devices that provide support and assistance for mobility, typically used by individuals who have difficulty walking or standing due to injury, illness, or disability. They help to reduce weight-bearing stress on the affected limb, improve balance, and increase stability during ambulation. Crutches can be either manually operated or designed with special features such as springs or shock absorbers to enhance comfort and functionality. Proper fit, adjustment, and usage of crutches are crucial for ensuring safety, preventing further injury, and promoting rehabilitation.

Lactate dehydrogenase-elevating virus (LDV) is an RNA virus that primarily infects mice. It is a member of the family Arteriviridae and is unique to murine species. LDV infection results in a persistent, chronic viremia without causing any overt signs of disease in the host. However, it is associated with a significant increase in serum lactate dehydrogenase (LDH) activity due to virus-induced damage to infected cells.

The virus infects various tissues and cell types, including macrophages and hepatocytes, and establishes a persistent infection by evading the host's immune response. LDV has been widely used as a model system for studying viral pathogenesis, persistence, and immunosuppression in mice.

It is important to note that Lactate dehydrogenase-elevating virus is not known to infect humans or other primates, and it is primarily studied in the context of basic research on viral infections and the immune response.

Enterovirus C, Human (HEV-C) is a type of enterovirus that infects humans. Enteroviruses are small viruses that belong to the Picornaviridae family and consist of a single strand of RNA enclosed in a protein shell. They are named "enteroviruses" because they are typically found in the gastrointestinal tract and are transmitted through the fecal-oral route.

HEV-C includes several serotypes, such as Coxsackievirus A21, A24, B3, B5, and Echovirus 9, 11, 16, 30. These viruses can cause a range of illnesses, from mild symptoms like fever, rash, and sore throat to more severe diseases such as meningitis, encephalitis, myocarditis, and paralysis.

HEV-C infections are common worldwide, and they often occur in children and young adults. The viruses can be spread through respiratory droplets, contaminated food or water, and direct contact with infected individuals. In many cases, HEV-C infections may not cause any symptoms or only mild ones, but some people may develop severe illnesses that require hospitalization.

Prevention measures include practicing good hygiene, such as washing hands frequently, avoiding close contact with sick individuals, and avoiding sharing food, drinks, or utensils with infected persons. There is no specific treatment for HEV-C infections, but supportive care can help manage symptoms and prevent complications.

The Pan American Health Organization (PAHO) is the specialized international health agency for the Americas. It is an integral part of the United Nations system and functions as the regional office for the Americas of the World Health Organization (WHO). PAHO's mission is to promote equity in health, to combat disease, and to improve the quality of, and length of, life among the peoples of the Americas. It aims to provide technical cooperation and mobilize partnerships to help countries improve their health systems and services, with an emphasis on those most in need. The organization also works to strengthen national and local health institutions and mobilize partnerships for the implementation of effective public policies and actions to combat diseases and injuries.

Czechoslovakia was a sovereign state in Central Europe that existed from October 28, 1918, when it declared its independence from the Austro-Hungarian Empire, until January 1, 1993. On that date, Czechoslovakia underwent a "velvet divorce" into two separate countries, the Czech Republic and Slovakia.

The medical definition of 'Czechoslovakia' is not applicable as it was a country and not a medical term or condition.

The Diphtheria-Tetanus-Pertussis (DTaP) vaccine is a combination immunization that protects against three bacterial diseases: diphtheria, tetanus (lockjaw), and pertussis (whooping cough).

Diphtheria is an upper respiratory infection that can lead to breathing difficulties, heart failure, paralysis, or even death. Tetanus is a bacterial infection that affects the nervous system and causes muscle stiffness and spasms, leading to "lockjaw." Pertussis is a highly contagious respiratory infection characterized by severe coughing fits, which can make it difficult to breathe and may lead to pneumonia, seizures, or brain damage.

The DTaP vaccine contains inactivated toxins (toxoids) from the bacteria that cause these diseases. It is typically given as a series of five shots, with doses administered at 2 months, 4 months, 6 months, 15-18 months, and 4-6 years of age. The vaccine helps the immune system develop protection against the diseases without causing the actual illness.

It is important to note that there are other combination vaccines available that protect against these same diseases, such as DT (diphtheria and tetanus toxoids) and Tdap (tetanus, diphtheria, and acellular pertussis), which contain higher doses of the diphtheria and pertussis components. These vaccines are recommended for different age groups and may be used as booster shots to maintain immunity throughout adulthood.

Antibodies, viral are proteins produced by the immune system in response to an infection with a virus. These antibodies are capable of recognizing and binding to specific antigens on the surface of the virus, which helps to neutralize or destroy the virus and prevent its replication. Once produced, these antibodies can provide immunity against future infections with the same virus.

Viral antibodies are typically composed of four polypeptide chains - two heavy chains and two light chains - that are held together by disulfide bonds. The binding site for the antigen is located at the tip of the Y-shaped structure, formed by the variable regions of the heavy and light chains.

There are five classes of antibodies in humans: IgA, IgD, IgE, IgG, and IgM. Each class has a different function and is distributed differently throughout the body. For example, IgG is the most common type of antibody found in the bloodstream and provides long-term immunity against viruses, while IgA is found primarily in mucous membranes and helps to protect against respiratory and gastrointestinal infections.

In addition to their role in the immune response, viral antibodies can also be used as diagnostic tools to detect the presence of a specific virus in a patient's blood or other bodily fluids.

Feces are the solid or semisolid remains of food that could not be digested or absorbed in the small intestine, along with bacteria and other waste products. After being stored in the colon, feces are eliminated from the body through the rectum and anus during defecation. Feces can vary in color, consistency, and odor depending on a person's diet, health status, and other factors.

I'm sorry for any confusion, but "Sudan" is not a medical term. It is a country located in Northeast Africa, known as the Sudan or Sudan proper, and the southern region that seceded to become South Sudan in 2011. If you have any medical terms you would like me to define, please let me know!

"Southern Africa" is a geographical region that includes several countries located in the southernmost part of the African continent. The specific countries that are included in this region can vary depending on the source, but it generally consists of Angola, Botswana, Eswatini (Swaziland), Lesotho, Malawi, Mozambique, Namibia, South Africa, Zambia, and Zimbabwe.

In medical terms, "Southern Africa" may be used to describe the epidemiology, distribution, or prevalence of various diseases or health conditions in this specific region. For example, a study might examine the burden of HIV/AIDS in Southern Africa, which has been disproportionately affected by this epidemic compared to other parts of the world. Similarly, researchers might investigate the prevalence of malaria or tuberculosis in Southern Africa, as these diseases are also significant public health challenges in this region.

It's worth noting that while "Southern Africa" is a useful geographical and medical designation, it does not encompass all of the countries on the African continent, and there can be significant variation in disease patterns and health outcomes within this region as well.

Depending on the site of paralysis, paralytic poliomyelitis is classified as spinal, bulbar, or bulbospinal. In those who ... bulbar polio occurs when poliovirus invades and destroys nerves within the bulbar region of the brain stem. The bulbar region ... This leads to the development of paralytic poliomyelitis, the various forms of which (spinal, bulbar, and bulbospinal) vary ... Miller AH, Buck LS (January 1950). "Tracheotomy in bulbar poliomyelitis". California Medicine. 72 (1): 34-36. PMC 1520308. PMID ...
Inflammatory/infective: Guillain-Barré syndrome, poliomyelitis, Lyme disease. Cancer: brainstem glioma, malignant meningitis. ... Bulbar palsy refers to a range of different signs and symptoms linked to impairment of function of the glossopharyngeal nerve ( ... Bulbar palsy involves problems with function of the glossopharyngeal nerve (CN IX), the vagus nerve (CN X), the accessory nerve ... In contrast, pseudobulbar palsy is a clinical syndrome similar to bulbar palsy but in which the damage is located in upper ...
In 1956, Watts contracted chronic bulbar poliomyelitis which left him with paraplegia. Having been unable to re-enter the ...
In the 1940s tonsillectomy became controversial as several studies linked it to bulbar poliomyelitis. From the 1940s to 1970s, ... further studies found an association between tonsillectomy and bulbar poliomyelitis with recommendations not to do the ... Kohanzadeh, Avraham; Somogyi, Dafna Z.; Kravitz, Meryl B. (19 August 2022). "Tonsillectomy and poliomyelitis: Development of ... "The Immunological Basis for Immunization Series Module 6: Poliomyelitis" (PDF). Retrieved 20 June 2019. "Polio , LCI ...
Bell's palsy, bulbar palsy, poliomyelitis and amyotrophic lateral sclerosis (ALS) are all pathologies associated with lower ...
Polio vaccination programs have virtually eradicated new cases of poliomyelitis in the developed world. Because of this, and ... with bulbar polio and bulbospinal polio. A polio patient with a paralyzed diaphragm would typically spend two weeks inside an ... The Both respirator, a negative pressure ventilator, was invented in 1937 when Australia's epidemic of poliomyelitis created an ... who had poliomyelitis. Despite this success, Henderson was reprimanded for secretly using hospital facilities to build the ...
... poliomyelitis MeSH C10.228.228.210.650 - poliomyelitis MeSH C10.228.228.210.650.600 - poliomyelitis, bulbar MeSH C10.228. ... poliomyelitis MeSH C10.228.854.641 - poliomyelitis MeSH C10.228.854.641.650 - postpoliomyelitis syndrome MeSH C10.228.854.761 ... bulbar palsy, progressive MeSH C10.574.562.500 - muscular atrophy, spinal MeSH C10.574.562.500.750 - spinal muscular atrophies ... bulbar palsy, progressive MeSH C10.668.460.500 - muscular atrophy, spinal MeSH C10.668.460.500.750 - spinal muscular atrophies ...
... poliomyelitis, and West Nile virus. The anterior grey column is the target for some spasmolytic medications. Norepinephrine ... spinal and bulbar muscular atrophy, Charcot-Marie-Tooth disease, progressive muscular atrophy, all spinal muscular atrophies, ...
... poliomyelitis MeSH C02.182.600.700.600 - poliomyelitis, bulbar MeSH C02.182.600.700.800 - postpoliomyelitis syndrome MeSH ... poliomyelitis MeSH C02.782.687.359.764.614 - poliomyelitis, bulbar MeSH C02.782.687.359.764.650 - postpoliomyelitis syndrome ...
Engstrom found that the iron lungs did not adequately ventilate patients with severe poliomyelitis. This problem solved ... with bulbar polio and bulbospinal polio. A polio patient with a paralyzed diaphragm would typically spend two weeks inside an ... West, John B. (2005). "The physiological challenges of the 1952 Copenhagen poliomyelitis epidemic and a renaissance in clinical ... Engström, C.-G. (1963). "Chapter III: Experience of Prolonged Controlled Ventilation in Poliomyelitis". Acta Anaesthesiologica ...
The symptoms of poliomyelitis have been described by many names. In the early nineteenth century the disease was known ... Even with an iron lung, the fatality rate for patients with bulbar polio exceeded 90%. These drawbacks led to the development ... Melnick JL (1990). Poliomyelitis. In: Tropical and Geographical Medicine (2nd ed.). McGraw-Hill. pp. 558-76. ISBN 0-07-068328-X ... Perhaps the earliest recorded case of poliomyelitis is that of Sir Walter Scott. In 1773, Scott was said to have developed "a ...
ISBN 978-0-470-02386-0. OCLC 124160564.[page needed] Acute Poliomyelitis at eMedicine Pediatric Poliomyelitis at eMedicine Yang ... In addition, these mice are capable of developing the bulbar form of polio after intranasal inoculation. The development of the ... Poliomyelitis is a disease of the central nervous system. However, CD155 is believed to be present on the surface of most or ... Paralytic poliomyelitis occurs in less than 1% of poliovirus infections. Paralytic disease occurs when the virus enters the ...
By 2004, cases of poliomyelitis in Africa had been reduced to just a small number of isolated regions in the western portion of ... thus eliminating the risk of bulbar polio and post-polio syndrome. In the United States, vaccine is administered along with the ... "Poliomyelitis". World Health Organization (WHO). Archived from the original on 18 April 2017. Retrieved 25 April 2017. "GPEI- ... 2021). "Chapter 18: Poliomyelitis". Epidemiology and Prevention of Vaccine-Preventable Diseases (14th ed.). Washington D.C.: U. ...
Stern suspected encephalitis lethargica to be close to poliomyelitis, without evidence. Nevertheless, he experimented with the ... bulbar paralysis, hystero-epilepsy, acute dementia, and sometimes just "an obscure disease with cerebral symptoms". Just 10 ...
Reincke, H; Nelson K R (January 1990). "Duchenne de Boulogne: electrodiagnosis of poliomyelitis" (PDF). Muscle Nerve. 13 (1): ... Progressive bulbar palsy). He was the first clinician to practise muscle biopsy, with an invention he called "l'emporte-pièce ...
Depending on the site of paralysis, paralytic poliomyelitis is classified as spinal, bulbar, or bulbospinal. In those who ... bulbar polio occurs when poliovirus invades and destroys nerves within the bulbar region of the brain stem. The bulbar region ... This leads to the development of paralytic poliomyelitis, the various forms of which (spinal, bulbar, and bulbospinal) vary ... Miller AH, Buck LS (January 1950). "Tracheotomy in bulbar poliomyelitis". California Medicine. 72 (1): 34-36. PMC 1520308. PMID ...
Bulbar palsy, poliomyelitis, myasthenia gravis. Spastic. Strained/harsh voice quality, hypernasal, slow rate, monopitch ...
Acute paralytic poliomyelitis specified as bulbar (045.0). 44 (0.3). Other specified nonarthropodborne viral diseases of ...
... : Introduction of A Sequential Vaccination Schedule of Inactivated Poliovirus ... Depending on the sites of paralysis, poliomyelitis can be classified as spinal, bulbar, or spino-bulbar disease. Progression to ... CHARACTERISTICS OF POLIOMYELITIS Acute Poliomyelitis Poliomyelitis is a highly contagious infectious disease caused by ... Bulbar paralysis may compromise respiration and swallowing. Paralytic poliomyelitis is fatal in 2%-10% of cases. After the ...
Categories: Poliomyelitis, Bulbar Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
By 1953, poliomyelitis was generally considered to be the most urgent disease problem in the nation, as mothers and fathers and ... to patient homes and regional hospital centers where severe cases with bulbar paralytic disease were gathered for respirator ( ... The EIS/CDC study of "Gamma Globulin for the Prevention of Poliomyelitis" did not reveal definitive utility, but it did help to ... "National Program for the Evaluation of Gamma Globulin for the Prevention of Poliomyelitis" during the last half of 1953. This ...
If the nerve cells of the brain are attacked (a condition known as bulbar poliomyelitis), the muscles controlling swallowing, ... Incidents of poliomyelitis can be traced back to ancient Egypt. The first recorded poliomyelitis epidemic (a rapidly spreading ... Poliomyelitis is infectious, meaning it is spread primarily through contact with someone who already has the disease. The virus ... Poliomyelitis, or polio, is a serious infectious disease that attacks muscle-controlling nerves and can eventually cause ...
Bulbar poliomyelitis. Giant cell arteritis Giant Cell Arteritis Giant cell arteritis involves predominantly the thoracic aorta ... bulbar motor nuclei... read more , progressive bulbar palsy, pseudobulbar palsy) ... bulbar motor nuclei... read more , multiple sclerosis Multiple Sclerosis (MS) Multiple sclerosis (MS) is characterized by ...
Bulbar poliomyelitis * Intracranial hypertension Drugs and toxins that cause hypertension include the following:. * Alcohol ...
Poliomyelitis, commonly known as polio, is an infectious viral disease caused by the genus Enterovirus from the Picornaviridae ... Bulbar polio: The virus affects the neurons responsible for sight, taste, swallowing, and breathing. ... Symptoms of Poliomyelitis. Non-paralytic polio symptoms. Non-paralytic polio, also called abortive poliomyelitis, leads to flu- ... Diagnosis of Poliomyelitis. Medical history. Medical history of the patient includes enquiry about exposure to a case of polio ...
Acute paralytic poliomyelitis specified as bulbar, poliovirus type I. ICD9CM. MGI. 324. Other CNS infection and poliomyelitis. ... Acute paralytic poliomyelitis specified as bulbar, poliovirus type II. ICD9CM. MGI. 324. Other CNS infection and poliomyelitis ... Acute paralytic poliomyelitis specified as bulbar, poliovirus type III. ICD9CM. MGI. 324. Other CNS infection and poliomyelitis ... Acute paralytic poliomyelitis specified as bulbar, poliovirus, unspecified type. ICD9CM. MGI. 324. Other CNS infection and ...
... and is used to provide respiration or breathing for patients who have been paralyzed by an acute bulbar poliomyelitis (a severe ...
Bulbospinal polio is a combination of bulbar and spinal paralysis.. Poliomyelitis was first recognized as a distinct condition ... Poliomyelitis, often called polio or infantile paralysis, is an acute viral infectious disease spread from person to person, ... Though not as devastating as the plague or influenza, poliomyelitis was a highly contagious disease that emerged in terrifying ... Following the widespread use of poliovirus vaccine in the mid-1950s, the incidence of poliomyelitis declined dramatically in ...
Bulbar involvement affects swallowing, speech, and cardiorespiratory function and accounts for most deaths ... "Poliomyelitis." Quick Medical Diagnosis & Treatment Pediatrics Hay, Jr WW, Levin MJ, Deterding RR, Abzug MJ. Hay, Jr W.W., & ... Poliomyelitis. In: Hay, Jr WW, Levin MJ, Deterding RR, Abzug MJ. Hay, Jr W.W., & Levin M.J., & Deterding R.R., & Abzug M.J.(Eds ... Poliomyelitis. Hay, Jr WW, Levin MJ, Deterding RR, Abzug MJ. Hay, Jr W.W., & Levin M.J., & Deterding R.R., & Abzug M.J.(Eds.), ...
Poliomyelitis. Health and Medicine Reference Covering Thousands of Diseases and Prescription Drugs. ... The three strains of poliovirus result in non-paralytic polio, paralytic polio, and bulbar polio. In all forms of polio, the ... Poliomyelitis. Poliomyelitis ("polio"), or infantile paralysis, is a viral paralytic disease. The causative agent, a virus ... Poliomyelitis in West Africa. According to the World Health Organization (WHO), a single case of paralytic poliomyelitis, with ...
Post-poliomyelitis syndrome (PPS) is characterized by the delayed appearance of new neuromuscular symptoms in patients several ... Clinical features of PPS include fatigue, joint and muscle pain, new muscular weakness and bulbar symptoms. The diagnosis is ... Palavras-chave : diagnosis differential; post-poliomyelitis syndrome; temporomandibular disorders. · texto em Inglês · pdf em ...
However, these "previously unaffected" muscles had subclinical involvement at the time of the acute poliomyelitis. About 50% of ... debilidad muscular bulbar (dificultad al tragar, para inhalar, pérdida de la voz) y apnea del sueño. Otros síntomas resultantes ... Excerpt from the "Handbook on the Late Effects of Poliomyelitis for Physicians and Survivors" ©1999 ... bulbar muscle weakness (swallowing difficulties, aspiration, loss of voice) (Sonies & Dalakas, 1995), and sleep apnea. Other ...
2018-04-05 · Bulbar Polio is a form of Paralytic Poliomyelitis in which the brainstem gets attacked by the poliovirus. Due to ... 2018-04-05 · Bulbar Polio is a form of Paralytic Poliomyelitis in which the brainstem gets attacked by the poliovirus. Due to ... Myasthenia gravis (MG) classically presents with ocular, bulbar, and predominantly proximal muscle weakness. Isolated bulbar ... Bulbar ALS disease is associated with muscle loss caused by degeneration of motor neurons in the medulla oblongata of the brain ...
Fox, M.J.; Chamberlain, J. 1953: Four fatal cases of bulbar poliomyelitis in one family. Journal of the American Medical ...
In 1949, Frederik Klenner first reported the successful treatment of bulbar poliomyelitis, with high doses of Vitamin C ... Frederick Klenner reported the successful treatment of 60 cases of bulbar poliomyelitis [14], with high doses of Vitamin C ... Klenner FR (1949) The treatment of poliomyelitis and other virus diseases with vitamin C. South Med Surg 111: 209-214. ... Klenner FR (1949) The treatment of poliomyelitis and other virus diseases with vitamin C. South Med Surg 111: 209-214. ...
Poliomyelitis is a contagious disease that spreads through person-to-person contact, mainly via the… ... poliomyelitis. It is a contagious disease that spreads by in person contact ... Poliovirus is the etiologic agent of the paralytic disease known as poliomyelitis. ... and bulbar. Accordingly, the nature of paralysis varies (e.g., respiratory insufficiency or dysphagia are common in bulbar ...
Poliomyelitis, Bulbar C2.182.600.700.600 C10.228.228.618.750.500 C10.228.228.210.650.600 C10.228.854.525.850.500 C10.668. ... Poliomyelitis C2.182.600.700 C10.228.228.618.750 C2.182.700 C10.228.228.210.575.750 C10.228.228.210.650 C10.228.228.618.850 ...
Acute paralytic poliomyelitis specified as bulbar 104510=Acute poliomyelitis with other paralysis 104520=Acute nonparalytic ... Osteopathy resulting from poliomyelitis of pelvic region/thigh 173076=Osteopathy resulting from poliomyelitis of lower leg ... Osteopathy resulting from poliomyelitis of shoulder region 173072=Osteopathy resulting from poliomyelitis of upper arm ... Osteopathy resulting from poliomyelitis of oth specified sites 173079=Osteopathy resulting from poliomyelitis of multiple ...
Poliomyelitis, Bulbar C2.182.600.700.600 C10.228.228.618.750.500 C10.228.228.210.650.600 C10.228.854.525.850.500 C10.668. ... Poliomyelitis C2.182.600.700 C10.228.228.618.750 C2.182.700 C10.228.228.210.575.750 C10.228.228.210.650 C10.228.228.618.850 ...
Poliomyelitis, Bulbar C2.182.600.700.600 C10.228.228.618.750.500 C10.228.228.210.650.600 C10.228.854.525.850.500 C10.668. ... Poliomyelitis C2.182.600.700 C10.228.228.618.750 C2.182.700 C10.228.228.210.575.750 C10.228.228.210.650 C10.228.228.618.850 ...
Poliomyelitis, Bulbar C2.182.600.700.600 C10.228.228.618.750.500 C10.228.228.210.650.600 C10.228.854.525.850.500 C10.668. ... Poliomyelitis C2.182.600.700 C10.228.228.618.750 C2.182.700 C10.228.228.210.575.750 C10.228.228.210.650 C10.228.228.618.850 ...
CD4 Deficiency Causes Poliomyelitis and Axonal Blebbing in Murine Coronavirus-Induced Neuroinflammation. ... Depletion of CD4+ T cells showed unique pathological bulbar vacuolation in the brain parenchyma of infected mice with ... Our study highlights the importance of CD4+ T cells in safeguarding neurons against axonal blebbing and poliomyelitis from ... the current study suggests that CD4+ T cells are critical for controlling acute-stage poliomyelitis (gray matter inflammation ...
Poliomyelitis, Bulbar C2.182.600.700.600 C10.228.228.618.750.500 C10.228.228.210.650.600 C10.228.854.525.850.500 C10.668. ... Poliomyelitis C2.182.600.700 C10.228.228.618.750 C2.182.700 C10.228.228.210.575.750 C10.228.228.210.650 C10.228.228.618.850 ...
  • Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. (wikipedia.org)
  • Two basic patterns of polio infection are described: a minor illness which does not involve the central nervous system (CNS), sometimes called abortive poliomyelitis, and a major illness involving the CNS, which may be paralytic or nonparalytic. (wikipedia.org)
  • Implementation of these recommendations should reduce the risk for vaccine-associated paralytic poliomyelitis and facilitate a transition to exclusive use of IPV following further progress in global polio eradication. (cdc.gov)
  • Poliomyelitis, or polio, is a serious infectious disease that attacks muscle-controlling nerves and can eventually cause paralysis. (scienceclarified.com)
  • Poliomyelitis, commonly known as polio, is an infectious viral disease caused by the genus Enterovirus from the Picornaviridae family. (diseasesdic.com)
  • The virus causes symptoms of both spinal and bulbar polio. (diseasesdic.com)
  • Poliomyelitis ("polio"), or infantile paralysis , is a viral paralytic disease. (the-medical-dictionary.com)
  • The three strains of poliovirus result in non-paralytic polio, paralytic polio, and bulbar polio. (the-medical-dictionary.com)
  • Cierta cantidad de nueva debilidad muscular es probable que ocurre en cerca de la mitad de los sobrevivientes de polio. (post-polio.org)
  • Esta nueva debilidad progresiva tiene muchas de las características de debilidad observadas durante el ataque agudo de la polio, es decir, es usualmente asimétrica, puede ser próximal[1] o distal[2], y es a menudo desigual (la debilidad puede afectar uno o dos músculos en una extremidad y saltarse los otros músculos). (post-polio.org)
  • 2018-04-05 · Bulbar Polio is a form of Paralytic Poliomyelitis in which the brainstem gets attacked by the poliovirus. (web.app)
  • Due to the respiratory system being involved in Bulbar Polio, it becomes a potentially serious condition which requires emergent treatment. (web.app)
  • No one could follow all those rules, but parents had no other way to try to safeguard children from the scourge of poliomyelitis, a viral disease then called infantile paralysis, and now known as polio. (historynet.com)
  • Bulbar polio struck the muscles employed to swallow and to breathe, killing by respiratory failure. (historynet.com)
  • Previously this listing used the term "Anterior Poliomyelitis, " but it is now titled "Post-Polio Syndrome. (disabilitysecrets.com)
  • The arms and legs are most often affected, but the muscles that control swallowing and breathing can also be weakened or paralyzed, this type of "bulbar" polio putting the patient's life in danger. (doclounge.net)
  • Polio vaccines are vaccines used to prevent poliomyelitis (polio). (wikipedia.org)
  • [2] Oral polio vaccines cause about three cases of vaccine-associated paralytic poliomyelitis per million doses given. (wikipedia.org)
  • [2] However, the emergence of circulating vaccine-derived poliovirus (cVDPV), a form of the vaccine virus that has reverted to causing poliomyelitis, has led to the development of novel oral polio vaccine type 2 (nOPV2) which aims to make the vaccine safer and thus stop further outbreaks of cVDPV2. (wikipedia.org)
  • Polio (poliomyelitis) is an infectious disease that affects the nervous system and can cause paralysis, usually in the legs and arms. (remodelormove.com)
  • Generally speaking, individuals who survived poliomyelitis are living active and full lives up to and beyond 70-80 years of age, with few post-polio sequelae. (remodelormove.com)
  • The prognosis for survivors of poliomyelitis may also be affected by the quality and duration of post-polio rehabilitative, medical, and supportive care, as well as the survivor's age at the onset of the disease. (remodelormove.com)
  • University of Michigan Medical School alumnus and bulbar polio survivor. (umich.edu)
  • Kommel-who also worked as a male nurse at the University Hospital-fell ill with bulbar polio in 1953. (umich.edu)
  • Post-polio syndrome (PPS) is a condition that can develop several decades after a person has had polio (poliomyelitis). (uky.edu)
  • Depending on the site of paralysis, paralytic poliomyelitis is classified as spinal, bulbar, or bulbospinal. (wikipedia.org)
  • Poliomyelitis, sometimes called infantile paralysis, is caused by one of three related viruses, and it primarily affects children. (scienceclarified.com)
  • Poliomyelitis is a paralytic disease resulting from the destruction of motor neurons in the central nervous system and can lead to partial or full paralysis. (diseasesdic.com)
  • Post-poliomyelitis syndrome (PPS) is characterized by the delayed appearance of new neuromuscular symptoms in patients several years after their acute poliomyelitis paralysis. (bvsalud.org)
  • N. Yesilot, Z. Matur Clinical signs and symptoms and physical examination findings alone cannot distinguish S pneumoniae Respiratory and bulbar paralysis is life-threatening. (web.app)
  • Diseases, symptoms or conditions for which acupuncture has been proved-through Paralysis, progressive bulbar and pseudobulbar. (web.app)
  • Accordingly, the nature of paralysis varies (e.g., respiratory insufficiency or dysphagia are common in bulbar involvement). (microbeonline.com)
  • Conditions which may present as AFP include wild and vaccine-acquired poliomyelitis, Guillain-Barr syndrome or transverse myelitis or traumatic paralysis. (health.gov.au)
  • acute onset of bulbar paralysis. (health.gov.au)
  • A higher percentage of affected sufferers need intubation due to decreased degree of awareness significantly, bulbar weakness, and intercostal and diaphragmatic muscle tissue paralysis (4,10). (bioshockinfinitereleasedate.com)
  • Poliovirus is the etiologic agent of the paralytic disease known as poliomyelitis. (microbeonline.com)
  • Clinical features of PPS include fatigue, joint and muscle pain, new muscular weakness and bulbar symptoms. (bvsalud.org)
  • Muscle weakness is most likely to occur in muscles previously affected during the acute poliomyelitis followed by a partial or full recovery (Cashman et al. (post-polio.org)
  • New muscle weakness can involve specific muscle groups and can result in respiratory insufficiency (Bach, 1995), bulbar muscle weakness (swallowing difficulties, aspiration, loss of voice) (Sonies & Dalakas, 1995), and sleep apnea. (post-polio.org)
  • Myasthenia gravis (MG) classically presents with ocular, bulbar, and predominantly proximal muscle weakness. (web.app)
  • This bulbar weakness - named for the nerves that originate from the bulblike part of the brainstem - can cause difficulty with talking (dysarthria), chewing, swallowing (dysphagia), and holding up the head. (web.app)
  • Weakness in the bulbar muscles resulting in the inability to breathe without mechanical ventilation or the need for enteral or parenteral nutrition. (disabilitysecrets.com)
  • Approximately 75% of patients with classic ALS also develop weakness and wasting of the bulbar muscles, which control speech, swallowing and chewing. (advancedpsy.com)
  • Weakness includes swallowing and other bulbar features. (abcmedicalnotes.com)
  • The term "poliomyelitis" is used to identify the disease caused by any of the three serotypes of poliovirus. (wikipedia.org)
  • These revised recommendations of the Advisory Committee on Immunization Practices (ACIP) replace recommendations on poliomyelitis issued in 1982 and 1987, and present a new ACIP poliovirus vaccination policy that increases reliance on inactivated poliovirus vaccine (IPV). (cdc.gov)
  • In particular, the relative benefits of OPV to the U.S. population have diminished because of the elimination of wild-virus-associated poliomyelitis in the Western Hemisphere and the reduced threat of poliovirus importation into the United States. (cdc.gov)
  • Since the introduction of poliovirus vaccines in the 1950s and 1960s, poliomyelitis control has been achieved in the United States, the Americas, and elsewhere (1,2). (cdc.gov)
  • In the United States, the last indigenously acquired cases of poliomyelitis caused by wild poliovirus were detected in 1979 (3). (cdc.gov)
  • In 1985, the countries of the Americas established a goal of regional elimination of wild poliovirus by the year 1990 (4), and in 1988, the World Health Assembly adopted the goal of global poliomyelitis eradication by the year 2000 (5). (cdc.gov)
  • In the Americas, the last case of poliomyelitis associated with isolation of wild poliovirus was detected in Peru in 1991 (6). (cdc.gov)
  • The United States can remain free of poliomyelitis only by reducing or eliminating the risk for poliovirus importation. (cdc.gov)
  • Poliomyelitis prevention in the United States: introduction of a sequential vaccination schedule of inactivated poliovirus vaccine followed by oral poliovirus vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). (cdc.gov)
  • Replication of poliovirus in motor neurons of the anterior horn and brain stem results in cell destruction and causes the typical manifestations of poliomyelitis. (diseasesdic.com)
  • Poliomyelitis is a disease caused by infection with the poliovirus. (diseasesdic.com)
  • Collecting at least two stool specimens 24 hours apart from suspected poliomyelitis patients is recommended to increase the probability of isolating poliovirus. (microbeonline.com)
  • If the nerve cells of the brain are attacked (a condition known as bulbar poliomyelitis), the muscles controlling swallowing, heartbeat, and breathing are paralyzed. (scienceclarified.com)
  • To help those people infected with poliomyelitis whose respiratory (breathing) muscles had been paralyzed, American physiologist Philip Drinker (1893-1977) invented the Drinker tank respirator (commonly known as the iron lung) in 1928. (scienceclarified.com)
  • However, these "previously unaffected" muscles had subclinical involvement at the time of the acute poliomyelitis. (post-polio.org)
  • In the most severe form, the bulbar, the virus paralyzes the muscles innervated by the cranial nerves, reducing the respiratory capacity, ingestion and speech. (breakinglatest.news)
  • The disorder progresses gradually over years and usually affects the legs first, followed by the trunk, arms and hands and finally the bulbar muscles. (advancedpsy.com)
  • Daube J.R. Statistical estimates of number of motor units in thenar and foot muscles in patients with amyotrophic lateral sclerosis or the residue of poliomyelitis. (annaly-nevrologii.com)
  • fem former: ALS (amyotrofisk lateral skleros), PLS (primär lateral skleros), PMA (progressiv muskulär atrofi), pseudobulbar pares och progressiv bulbar pares. (web.app)
  • Pseudobulbar Palsy shares many of the symptoms of progressive bulbar palsy and is characterized by upper motor neuron degeneration and progressive loss of the ability to speak, chew and swallow. (advancedpsy.com)
  • It includes a number of overlapping syndromes, such as pseudobulbar palsy, progressive bulbar palsy, progressive muscular atrophy, and primary lateral sclerosis. (unboundmedicine.com)
  • The risk for vaccine-associated poliomyelitis caused by OPV is now judged less acceptable because of the diminished risk for wild-virus-associated disease (indigenous or imported). (cdc.gov)
  • Vaccine-associated paralytic poliomyelitis (VAPP) has been the only indigenous form of the disease in the United States since 1979. (cdc.gov)
  • Progressive Bulbar Palsy (PBP) involves the bulb shaped brainstem that controls lower motor neurons needed for swallowing, speaking, chewing and other functions. (advancedpsy.com)
  • La debilidad muscular es más probable que aparezca en músculos previamente afectados durante el ataque agudo de poliomielitis, seguida de una recuperación total o parcial. (post-polio.org)
  • La nueva debilidad muscular puede involucrar grupos específicos de músculos y puede dar como resultado una insuficiencia respiratoria, debilidad muscular bulbar (dificultad al tragar, para inhalar, pérdida de la voz) y apnea del sueño. (post-polio.org)
  • Otros síntomas resultantes de esta nueva disfunción neruromuscular son el incremento en la fatigabilidad muscular, descrita como un rápido debilitamiento de un músculo en ejercicio que luego se recobra rápidamente (desde minutos hasta horas) dependiendo de la cantidad de sobreuso, y el dolor y la delicadeza musculares. (post-polio.org)
  • The World Health Organization (WHO) aims to eradicate poliomyelitis from the Western Pacific Region by the year 2000. (health.gov.au)
  • 1. The electrical stimulation of the phrenic nerve, and is used to provide respiration or breathing for patients who have been paralyzed by an acute bulbar poliomyelitis (a severe form of viral disease affecting the medulla oblongata, which may result in a dysfunction of the swallowing mechanism, normal breathing, and circulatory distress). (wordinfo.info)
  • The Hospital became a specialist centre for the treatment of bulbar poliomyelitis, a severe form of the infection which affects the nerve cells in the medulla oblongata, resulting in dysfunction of the swallowing mechanism, respiratory embarrassment and circulatory distress. (myzen.co.uk)
  • Admission to the intensive care unit (ICU) should be considered for all patients with labile dysautonomia, a forced vital capacity of less than 20 mL/kg, or severe bulbar palsy. (medscape.com)
  • 1 At clinical onset, manifestations appear rather focal, resulting in bulbar, cervical or lumbar phenotypes. (bmj.com)
  • People with ALS now have more options to deal with a distressing set of symptoms called bulbar signs. (web.app)
  • Isolated bulbar symptoms occur in less than There are many symptoms associated with brain cancer and tumors, which is why it is important to see a doctor if you experience them frequently. (web.app)
  • För andra observerade symptomgrupper, inklusive beteendemässiga, kognitiva eller motoriska / bulbar symtom, fanns det ingen signifikant Tell me of any other symptoms you may be having as these can help also. (web.app)
  • The bulbar region of the brain is responsible for controlling the Till exempel visar hans undersökningar att bulbär varianterna av MND Studien "Säkerhet och effekt av nabiximoler pÃ¥ spasticitets symptom Forskarna kommer titta om C-vitamin kan förebygga lÃ¥ngsiktiga symptom, om de in patients with ALS, especially in those with existing bulbar symptoms. (web.app)
  • The global poliomyelitis eradication initiative (PEI) has reduced the number of reported poliomyelitis cases worldwide by more than 80% since the mid-1980s, and worldwide eradication of the disease by the year 2000 appears feasible (8). (cdc.gov)
  • Nonparalytic poliomyelitis is seen in 1% of patients who presented with aseptic meningitis. (microbeonline.com)
  • Bulbar ALS disease is associated with muscle loss caused by degeneration of motor neurons in the medulla oblongata of the brain. (web.app)
  • Do not run anything What do we mean by bulbar and neuromuscular dysfunction? (web.app)
  • 3 This method has the benefit of avoiding the need for a firm mouth seal in patients with bulbar dysfunction. (rcjournal.com)
  • Many poliomyelitis patients were kept alive in such a manner, but it was not a cure for the disease. (scienceclarified.com)
  • Bulbar form of ALS is characterized by breathing difficulty and problems with swallowing. (web.app)
  • That the tonsil elaborates immunoglobulins, participates in cell-mediated immunity which apparently aborts certain kinds of malignancy, and contributes to the general resistance of the body such as in averting Hodgkin's disease, multiple sclerosis, bowel infections, and bulbar poliomyelitis, has been established. (lml.com.ly)
  • Stool testing also has the additional advantage of identifying other viruses which can cause poliomyelitis-like illness. (health.gov.au)
  • Amyotrophic Lateral Sclerosis (ALS) and Other Motor Neuron Diseases (MNDs) Amyotrophic lateral sclerosis and other motor neuron diseases are characterized by steady, relentless, progressive degeneration of corticospinal tracts, anterior horn cells, bulbar motor nuclei. (msdmanuals.com)
  • Since 1980, an average of eight to nine cases of paralytic poliomyelitis associated with OPV has been reported annually in the United States. (cdc.gov)
  • Poliomyelitis - Description, Causes, and Treatment. (diseasesdic.com)
  • Referral for swallowing evaluation and treatment is very important for those with impaired bulbar function. (rcjournal.com)
  • Poliomyelitis occurred worldwide, but is not limited to Asia and African continents. (diseasesdic.com)
  • Poliomyelitis has existed for thousands of years, with depictions of the disease in ancient art. (wikipedia.org)