Strychnos nux-vomica
Infection Control
Relationship between skeletal muscle-specific calpain and tenderness of conditioned porcine longissimus muscle. (1/559)
Tenderization of skeletal muscle in meat animals has been closely linked to the postmortem activity of the calpain proteolytic enzyme system, which includes the specific inhibitor calpastatin. Increased understanding of the skeletal muscle-specific calpain isoform p94 has prompted suggestions as to whether it too could have a role in the tenderization process. In this study, two groups of pigs were identified in which shear force measurements after 8 d of conditioning indicated a large variation in the tenderness of longissimus muscle. The quantity of p94 in the muscle was monitored by immunoblotting, using a porcine-specific polyclonal antibody raised against a recombinant peptide fragment generated as a fusion protein. The antiserum recognized a 94-kDa protein associated with myofibrils in skeletal but not cardiac muscle, as expected for this calpain isoform, although it could not be tested with the native protein because of the extreme instability of p94. In the first experiment, the mean shear force for the tough group was 6.71 +/- .28 kg (n = 12, SEM) and that of the tender group was 3.87 +/- .12 kg (n = 12), but there was no difference in the normalized absorbance of the immunopositive 94 kDa band on Western blots from samples collected at approximately 40 min postmortem. In the second experiment, the stability of p94 in chilled carcasses was investigated over 24 h, using a further two groups of 10 tough and 10 tender pigs of mean shear force values 5.36 +/- .14 kg and 2.81 +/- .15 kg, respectively. In tough and tender animals, there was a decline (P < .05) in the 94-kDa immunostaining material of mean half-lives of 13.8 and 12.9 h, respectively, although there was considerable variability. Despite this variability in half lives and shear force values, no correlation was seen between these factors. Thus, in porcine longissimus muscle, the variability in tenderness after 8 d of conditioning cannot be attributed to an underlying variability in p94. (+info)Immunoblot analysis of calpastatin degradation: evidence for cleavage by calpain in postmortem muscle. (2/559)
A negative correlation exists between calpastatin activity and meat tenderness. Therefore, it is important to determine the mechanism of calpastatin inactivation in postmortem skeletal muscle. Western immunoblot analysis was performed to determine the protease(s) responsible for degradation of muscle calpastatin during postmortem storage. To accomplish this, purified calpastatin was digested with different proteases in vitro, and their pattern of calpastatin degradation was compared with that of calpastatin degradation in postmortem muscle. Polyclonal antibodies raised in mice against recombinant bovine skeletal muscle calpastatin were used to monitor calpastatin degradation. Lamb longissimus was stored at 4 degrees C and sampled at 0, 6, 12, 24, 72, 168, and 336 h postmortem. Postmortem storage produced a discrete pattern of calpastatin degradation products that included immunoreactive bands at approximately 100, 80, 65, 54, 32, and 29 kDa. Undegraded calpastatin (130 kDa) was barely detectable after 72 h of postmortem storage at 4 degrees C, and no immunoreactive calpastatin was observed by 336 h postmortem. For in vitro proteolysis, lamb longissimus calpastatin (0 h postmortem) was purified using Affi-Gel Blue chromatography. Calpastatin was digested with m-calpain, mu-calpain, cathepsin B, proteasome, trypsin, or chymotrypsin. Each of these enzymes degraded calpastatin. Immunoreactive fragments resulting from digestion of calpastatin with m- and mu-calpain were similar to each other and closely resembled those observed during postmortem aging of lamb longissimus at 4 degrees C. Digestion of calpastatin with mu-calpain reduced calpastatin activity. Degradation of calpastatin by other proteases resulted in unique patterns of immunoreactive fragments, distinct from that observed in longissimus. Thus, m- and(or) mu-calpain seem to be responsible for calpastatin degradation during postmortem storage of meat. (+info)Postmortem proteolysis and calpain/calpastatin activity in callipyge and normal lamb biceps femoris during extended postmortem storage. (3/559)
The present experiment was conducted to determine whether calpastatin inhibits only the rate, or both the rate and extent, of calpain-induced postmortem proteolysis. Biceps femoris from normal (n = 6) and callipyge (n = 6) lamb was stored for 56 d at 4 degrees C. Calpastatin activity was higher (P < .05) in the callipyge muscle at 0 and 14 d postmortem, but not at 56 d postmortem. The activity of mu-calpain did not differ between normal and callipyge biceps femoris at 0 and 56 d postmortem (P > .05), but was higher at 14 d postmortem in the callipyge muscle (P < 0.05). The activity of m-calpain was higher in the callipyge muscle (P < 0.05). Western blot analyses of titin, nebulin, dystrophin, myosin heavy chain, vinculin, alpha-actinin, desmin, and troponin-T indicated that postmortem proteolysis was less extensive in callipyge than in normal biceps femoris at all postmortem times. The results of this experiment indicate that calpastatin inhibits both the rate and extent of postmortem proteolysis. (+info)Angiotensin-converting enzyme in non-neoplastic kidney diseases. (4/559)
BACKGROUND: The angiotensin I-converting enzyme (ACE, CD143, kininase II) plays a critical role in controlling the level of vasoactive peptides such as angiotensins and kinins in the local circulations and tissue interstitium. Because recent work has documented a vessel-, organ-, and species-specific pattern of endothelial ACE expression in the vascular system, we have analyzed whether or not changes of this pattern occur in vessels, tubules, and interstitium of the human kidney that is affected by different non-neoplastic diseases. METHODS: Using a set of well-characterized monoclonal antibodies (mAbs), ACE was assessed on renal tissue of 135 patients by immunohistochemistry, including an additional analysis at the ultrastructural level. A semiquantitative evaluation allowed the estimation and comparison of ACE content in different renal compartments. These data were compared with several clinical findings, diagnosis, therapeutic modalities, and histological features. RESULTS: In contrast to the normal human kidney, where ACE is abundant in the brush border of the proximal tubule but is usually absent in endothelial cells of any vessel type, an endothelial neoexpression of ACE was observed in different diseases. In general, this neoexpression was associated with histological sites of interstitial fibrosis and showed some selectivity for glomerular endothelial cells in diabetes mellitus and chronic arterial hypertension. There was also a loss of epithelial ACE in the proximal tubule in certain pathological conditions, for example, in chronic fibroplastic processes, acute pyelonephritis, and different stages of acute renal failure. CONCLUSIONS: Neoexpression of ACE by renal endothelial cells, as well as changes of the tubular ACE content, is a common finding in diseased human kidneys. As associated with certain tissue sites, clinical and/or morphological features, these changes may be involved in parenchymal remodeling and renal pathophysiology. (+info)Effect of calpastatin on degradation of myofibrillar proteins by mu-calpain under postmortem conditions. (5/559)
To improve our understanding of the regulation of mu-calpain activity in situ during postmortem storage of muscle, the effect of different calpastatin levels on proteolysis of myofibrillar proteins by mu-calpain in a system closely mimicking postmortem conditions was studied. Increasing the amount of calpastatin in the incubations limited both the rate and extent of proteolysis of myofibrillar proteins and autolysis of mu-calpain. Excess calpastatin (i.e., a mu-calpain:calpastatin ratio of 1:4) did not inhibit proteolysis completely. Western blot analysis revealed that proteolysis of myofibrillar proteins virtually ceased after 7 d of incubation, despite the presence of partly autolyzed, therefore seemingly active, mu-calpain. A series of incubations of autolyzed mu-calpain revealed that the autolyzed form of this enzyme is unstable at an ionic strength observed in postmortem muscle. The possible significance of these results in terms of the regulation of mu-calpain activity in postmortem muscle is discussed. (+info)Evaluation of calpastatin activity measures in ante- and postmortem muscle from half-sib bulls and steers. (6/559)
Calpastatin activity measured at 24 h postmortem in bovine longissimus muscle (PMLD24) is correlated with Warner-Bratzler shear force (WBS) measurements, an objective measure of tenderness. A live-animal measurement of calpastatin activity that correlates with 24-h postmortem activity would provide information for selection programs without the expense of progeny testing. The purpose of this study was to evaluate the effectiveness of calpastatin activity measurements obtained on tissue samples from live animals and to determine the relationship among various calpastatin activity measures and tenderness determined by WBS and sensory panel. Biopsies (approximately 10 g) were obtained surgically 2 d before slaughter from the supraspinatus muscle on the anterior surface of the scapula (LISH0) from contemporary purebred Angus bulls (n = 12) and steers (n = 17). Biopsies from a subset of these cattle (n = 12) were refrigerated at 4 degrees C to simulate the postmortem cooling process for 24 h (LISH24) prior to extraction. A rib section anterior to the 12 and 13th rib interface was collected from all animals at the commercial abattoir between 22 and 23 h postmortem for PMLD24, sensory panel, and WBS measurements. A postmortem shoulder muscle sample (PMSH24) was collected at the same time. Calpastatin was extracted from all muscle samples using a heated calpastatin activity protocol. Sensory panel tenderness, WBS, LISH0, LISH24, and PMSH24 were not different between bulls and steers. However, PMLD24 values were significantly different. Significant partial correlations were found between WBS and sensory panel tenderness (-.55), between WBS and PMLD24 (-.43), and between LISH24 and PMLD24 (.78). Therefore, similar calpastatin activity values are possible with ante- and postmortem tissue samples, suggesting the possibility of using measurements from live-tissue biopsies from other than the longissimus muscle to predict end product tenderness. (+info)Visualization of the basilar artery by transcranial color-coded duplex sonography : comparison with postmortem results. (7/559)
BACKGROUND AND PURPOSE: Transcranial color-coded sonography (TCCS) via the suboccipital approach allows direct and continuous visualization of the basilar artery (BA). In this study, we intended to evaluate the ability of native TCCS in visualizing the length of the BA by means of a comparison with postmortem measurements. METHODS: The BA was prospectively studied by TCCS shortly before death (median 3 days) in 46 moribund neurological patients (mean+/-SD age 71.1+/-13.1 years). The length of the BA was determined by measuring the distance between the vertebrobasilar junction and the deepest available flow signal in the top of the BA. During autopsy, photos of the vertebrobasilar system were taken to evaluate the true anatomic length and variations of the course of BA in situ, eg, straight, curved, or S-shaped. RESULTS: Comparison of the in vivo ultrasound measurements of BA length and postmortem data was possible in 44 of 46 cases. In the 2 remaining patients, the BA was occluded. The mean insonation depth of the vertebrobasilar junction was found at 66.9+/-7.1 mm. The mean BA length was 21.5+/-6. 8 mm by color-coded duplex and 32.9+/-6 mm anatomically (P<0.0001). The mean difference between color mode and anatomic findings was 11. 3+/-6.4 mm in the case of a straight BA (35 cases) and 16.3+/-4.8 mm in an anatomically tortuous course of the BA (9 cases). CONCLUSIONS: Color duplex imaging enables correct visualization of the proximal two thirds of the BA, but only exceptionally of its distal one third. A tortuous course of the BA leads to an underestimation of its anatomic length. (+info)Estimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution. (8/559)
AIMS: To compare blood drug concentrations during life with postmortem drug concentrations measured from a peripheral site and a central site. METHODS: Coroner's cases from October 1990 to July 1997 were reviewed. Six cases had data on both antemortem and postmortem blood drug concentrations. The postmortem to antemortem ratio was compared with the postmortem central to peripheral ratio, using cardiac blood as a central site and femoral blood as a peripheral site. RESULTS: Drugs that have a high postmortem central to peripheral ratio; that is, drugs that exhibit considerable postmortem redistribution, also have high postmortem to antemortem ratios. CONCLUSIONS: A large degree of error can arise from attempting to estimate antemortem drug concentrations and the ingested dose from postmortem measurements. The chosen site and technique for postmortem blood sampling can greatly influence the concentration of drug measured. (+info)"Postmortem changes," also known as "autolysis" or "decomposition," refer to the natural biological processes that occur in a deceased body after death. These changes include various chemical, physical, and biological alterations such as livor mortis (pooling of blood), algor mortis (drop in body temperature), rigor mortis (stiffening of muscles), putrefaction (breakdown by microorganisms), and decomposition by insects and other animals. These changes help forensic experts estimate the time since death, known as the postmortem interval.
An autopsy, also known as a post-mortem examination or obduction, is a medical procedure in which a qualified professional (usually a pathologist) examines a deceased person's body to determine the cause and manner of death. This process may involve various investigative techniques, such as incisions to study internal organs, tissue sampling, microscopic examination, toxicology testing, and other laboratory analyses. The primary purpose of an autopsy is to gather objective evidence about the medical conditions and factors contributing to the individual's demise, which can be essential for legal, insurance, or public health purposes. Additionally, autopsies can provide valuable insights into disease processes and aid in advancing medical knowledge.
Forensic dentistry, also known as forensic odontology, is a specialty in forensic science that involves the examination, identification, and evaluation of dental evidence for legal purposes. It encompasses various aspects such as:
1. Identification of deceased individuals through dental records comparison (e.g., during mass disasters or unidentified human remains).
2. Analysis of bite marks found on victims or objects related to criminal investigations.
3. Assessment of age, sex, ancestry, and other personal characteristics based on dental features.
4. Examination of cases of abuse, neglect, or malpractice in dentistry.
5. Evaluation of occupational dental injuries and diseases.
Forensic dentists often work closely with law enforcement agencies, medical examiners, and other legal professionals to provide expert testimony in court proceedings.
'Strychnos nux-vomica' is a plant species also known as the poison nut tree or strychnine tree. Its seeds, known as nux vomica, contain several alkaloids including strychnine and brucine, which have been used in medicine for their stimulant and convulsant properties. However, due to the high toxicity and narrow therapeutic index of these compounds, the use of 'Strychnos nux-vomica' in modern medicine is very limited and generally not recommended.
It's important to note that while some alkaloids found in 'Strychnos nux-vomica' have been used in homeopathy, there is a lack of scientific evidence supporting their efficacy, and they should only be used under the guidance of a qualified healthcare professional.
'Infection Control' is a set of practices, procedures, and protocols designed to prevent the spread of infectious agents in healthcare settings. It includes measures to minimize the risk of transmission of pathogens from both recognized and unrecognized sources, such as patients, healthcare workers, visitors, and the environment.
Infection control strategies may include:
* Hand hygiene (handwashing and use of alcohol-based hand sanitizers)
* Use of personal protective equipment (PPE), such as gloves, masks, gowns, and eye protection
* Respiratory etiquette, including covering the mouth and nose when coughing or sneezing
* Environmental cleaning and disinfection
* Isolation precautions for patients with known or suspected infectious diseases
* Immunization of healthcare workers
* Safe injection practices
* Surveillance and reporting of infections and outbreaks
The goal of infection control is to protect patients, healthcare workers, and visitors from acquiring and transmitting infections.
Forensic Toxicology is a branch of toxicology that applies scientific methods and techniques to investigate and provide information about the presence, identity, concentration, and effects of drugs, poisons, or other chemicals in biological specimens (such as blood, urine, tissues) within a legal context. It is often used in criminal investigations, medical examinations, and workplace drug testing to determine the cause of death, poisoning, impairment, or other health effects related to exposure to toxic substances. Forensic toxicologists may also provide expert testimony in court based on their findings.
Forensic medicine, also known as legal medicine or medical jurisprudence, is a branch of medicine that deals with the application of medical knowledge to legal issues and questions. It involves the examination, interpretation, and analysis of medical evidence for use in courts of law. This may include determining the cause and manner of death, identifying injuries or diseases, assessing the effects of substances or treatments, and evaluating the competency or capacity of individuals. Forensic medicine is often used in criminal investigations and court cases, but it can also be applied to civil matters such as personal injury claims or medical malpractice suits.
Postmortem studies
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Postmortem (novel)
Post-mortem interval
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Postmortem studies - Wikipedia
COVID-19 Guidance Postmortem Specimens | CDC
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TPP: A Post-Mortem | Electronic Frontier Foundation
Postmortem Changes: Overview, Definitions, Scene Findings
Post Mortem
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Firefox/Channels/Postmortem/91 - MozillaWiki
Postmortem
PostgreSQL: Re: gitlab post-mortem: pg basebackup waiting for checkpoint
An Incident Post-Mortem - Speaker Deck
Serie: Post mortem » Bokkilden
Post mortem ?
Releases:Release Post Mortem:2014-07-15
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A Painful Post Mortem by Mel Menzies
the preselection post-mortem Archives - New Matilda
VP Debate Postmortem: Unflappable Pence Won Against Smug Kaine 10/05/2016
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GRAMMY POST-MORTEM : HITS Daily Double
Differences in Morphological Age-Related Dental Changes Depending on Postmortem Interval
Postmortem profiling for Call Count and Function Instrumentation profiling
Estimate the postmortem interval2
- [ 1 ] Understanding common postmortem changes and the variables that affect them allows the forensic pathologist to more accurately estimate the postmortem interval (PMI) and to provide a time frame during which death occurred. (medscape.com)
- Forensic anthropologists often rely on the state of decomposition to estimate the postmortem interval (PMI) in a human remains case. (astm.org)
Autopsy7
- Recommendations about the type of postmortem specimens to collect vary based on whether the case of COVID-19 is suspected or confirmed, as well as whether an autopsy is performed. (cdc.gov)
- Further, an awareness of common postmortem artifacts limits the risk of misdiagnosis at the time of autopsy. (medscape.com)
- These alterations may eventually produce great distortion of the body after death, hampering the interpretation of the postmortem findings but not ameliorating the value of the autopsy. (medscape.com)
- [ 1 , 6 ] Despite the degradation the body undergoes during the postmortem period, a complete autopsy of a decomposing body often yields abundant information. (medscape.com)
- 3) The coroner, the medical examiner, or the attending physician shall, upon request, meet with the family of the decedent to discuss the findings of the autopsy or postmortem. (wa.gov)
- Conclusions: The detection of SARS-CoV-2 in postmortem examination can be an incidental or contributory finding which highlights the value of autopsy examination to determine the exact cause of death in controversial cases. (lu.se)
- This study was conducted to determine stature and sex according to mandibular dimensions in postmortem autopsy samples. (bvsalud.org)
20161
- Tetsuya Mizuguchi, the remarkable designer best known as the creator behind critically-acclaimed games like Space Channel 5, Lumines and Child of Eden will be delivering a Classic Game Postmortem on his groundbreaking rhythm game Rez at GDC 2016! (gdcvault.com)
Interval6
- We found vere acute respiratory syndrome coronavirus 2 is highly no correlation between the postmortem interval (time transmissive. (cdc.gov)
- The median postmortem interval through droplet and contact-transmitted viral spread- was 5.7 (range 2.9-32.0 [IQR 6.9]) hours. (cdc.gov)
- A) Correlation of SARS-CoV-2 RNA loads of the pharynx (at corpse admission to the Department of Legal Medicine) with the postmortem interval (time of death until cooling at 4°C) in 79 matched datasets. (cdc.gov)
- Morphological methods for age estimation from teeth have been developed and applied to samples without taking the postmortem interval into consideration. (astm.org)
- Forty-three permanent teeth from dental patients were compared to 37 teeth obtained from human skeletal remains with a postmortem interval from 21 to 37 years. (astm.org)
- The postmortem interval affects age-related morphological changes, and therefore different methods should be used for teeth of unknown postmortem interval. (astm.org)
Examination1
- Hydronephrosis is found at postmortem examination in 2 to 4% of patients. (msdmanuals.com)
Swab1
- Updates to postmortem swab and fixed tissue specimen collection and submission procedures. (cdc.gov)
Antemortem1
- Postmortem changes may partially obscure antemortem trauma and disease or mimic their presence. (medscape.com)
Antigen2
Donor2
- We identified West Nile Virus RNA in spleen/lymph node homogenate, skin, fat, muscle, tendon, and bone marrow samples obtained postmortem from a donor associated with transmission of West Nile Virus through solid organ transplantation. (cdc.gov)
- Postmortem evaluation of the donor showed only evidence of previous Epstein-Barr virus infection. (medscape.com)
Viral2
- Because subsequent samples a study of postmortem viral RNA stability. (cdc.gov)
- Title : Collection and submission of postmortem specimens from deceased persons with known or suspectd COVID-19 : interim guidance Corporate Authors(s) : National Center for Immunization and Respiratory Diseases (U.S.). Division of Viral Diseases. (cdc.gov)
Tissue3
- When tissue from a postmortem study is obtained it is imperative that the researcher ensures the quality is adequate to study. (wikipedia.org)
- Another benefit to postmortem studies is that researchers have the ability to make a wide range of discoveries, because of the many different techniques used to obtain tissue samples. (wikipedia.org)
- Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mechanisms. (lu.se)
Researchers6
- Postmortem studies are a type of neurobiological research, which provides information to researchers and individuals who will have to make medical decisions in the future. (wikipedia.org)
- Postmortem researchers conduct a longitudinal study of the brain of an individual, who has some sort of phenomenological condition (i.e. cannot speak, trouble moving left side of body, Alzheimer's, etc.) that is examined after death. (wikipedia.org)
- Postmortem studies provide a unique opportunity for researchers to study different brain attributes that would be unable to be studied on a living person. (wikipedia.org)
- Postmortem studies allow researchers to determine causes and cure for certain diseases and functions. (wikipedia.org)
- Postmortem studies allows for researchers to give information that is relevant to individuals by explaining the causes of particular diseases and behaviors. (wikipedia.org)
- The researchers also accessed postmortem brain samples from participants in the Religious Orders Study (ROS) and the Rush Memory and Aging Project (MAP). (medscape.com)
Samples1
- Postmortem brain samples are limited resources, because it is extremely difficult for a researcher to get a hold of an individual's brain. (wikipedia.org)
Study2
- Another limitation to postmortem studies is the continuous funding and the time it takes to conduct a longitudinal study. (wikipedia.org)
- Morphometric measurements of mandible to determine stature and sex: A postmortem study. (bvsalud.org)
Brain4
- Postmortem studies have been used to further the understanding of the brain for centuries. (wikipedia.org)
- Paul Broca used postmortem studies to link a specific area of the brain with speech production. (wikipedia.org)
- Karl Wernicke also used postmortem studies to link specific areas of the brain with speech production. (wikipedia.org)
- Postmortem studies also improve medical knowledge and help to determine whether changes happen in the brain itself or in the actual disorder. (wikipedia.org)
Time3
- Postmortem longitudinal studies usually take place at the time of assessment until the time of death about 20-30 years. (wikipedia.org)
- Although there is quite a lot of variability in the time schedule of common postmortem changes, all bodies eventually decompose to some degree. (medscape.com)
- Time for my usual postmortem. (pyweek.org)
Case1
- A case of aphasia with postmortem verification. (bvsalud.org)
Reports2
Good1
- But one secret to good postmortems is not blaming others. (avc.com)
Read1
- I look forward to read the ECC postmortem. (wadjeteyegames.com)
Years1
- The session is a postmortem on 8 years of Mafia II development from inception to release in 2010 and also focuses on how the local development team Illusion Softworks has changed into a premium international development house 2K Czech. (gdcvault.com)
Death1
- All bodies undergo some degree of postmortem change after death. (medscape.com)
Medical1
- Medical examiners, coroners, and other healthcare professionals should use professional judgment to determine if a decedent had signs and symptoms compatible with COVID-19 during life and whether postmortem testing is necessary. (cdc.gov)
Decisions1
- One of the best ways to get smarter and better at something is to do frequent postmortems after bad decisions. (avc.com)
Median postmortem1
- The median postmortem interval through droplet and contact-transmitted viral spread- was 5.7 (range 2.9-32.0 [IQR 6.9]) hours. (cdc.gov)
Skip1
- You may be tempted to skip a formal incident postmortem meeting and write-up, especially if you are certain of what caused the incident, and you're pretty sure you've fixed the issue. (atlassian.com)
Findings1
- The findings from your postmortem should feed right back into your planning process. (atlassian.com)
Specimens1
- Range and ratios of concentrations reported in traditional and non-traditional postmortem specimens, blood, urine, vitreous humor, liver and brain, are summarized in tables. (nih.gov)
Decomposition1
- The Forensic Anthropology Center, at the University of Tennessee, Knoxville, conducts research into the postmortem decomposition of the human body. (nih.gov)
Examinations2
- Doctors have conducted postmortem examinations since, at least, the Renaissance. (medscape.com)
- Novel postmortem examinations. (cdc.gov)
Metabolism2
- pHu variation is often associated with postmortem muscle glycogen content and metabolism, which is affected by many factors including psychological stress, animal diet, season, transport, and lairage times, thus affecting initial meat shear force values and rate of tenderization [ 7 ]. (hindawi.com)
- These factors include key chemical properties, essential pharmacokinetics parameters (metabolism), postmortem redistribution and stability data in postmortem samples. (nih.gov)
Neurobiological2
- Postmortem studies are a type of neurobiological research, which provides information to researchers and individuals who will have to make medical decisions in the future. (wikipedia.org)
- ADMINISTRATIVE SUPPLEMENTS FOR HUMAN POSTMORTEM BRAIN RESEARCH IN MENTAL ILLNESSES Release Date: October 30, 2001 NOTICE: NOT-MH-01-010 National Institute of Mental Health ( http://www.nimh.nih.gov/ ) Receipt Date: January 15, 2002 PURPOSE The National Institute of Mental Health (NIMH) seeks to support supplements for the utilization of human postmortem brain tissue in neurobiological studies of mental illnesses such as schizophrenia and depression. (nih.gov)
Stability2
- To analyze postmortem stability of SARS-CoV-2 etailed analyses of severe acute respiratory syn- RNA, we selected 11 corpses with short postmortem drome coronavirus 2 (SARS-CoV-2) transmis- intervals for a detailed observation over 7 days (168 sion have shown the virus to be highly transmissible hours) (Table). (cdc.gov)
- Because subsequent samples a study of postmortem viral RNA stability. (cdc.gov)
Interpretation2
- The analytical identification of these opioids in postmortem samples and the correct toxicological data interpretation is critical to identify and implement preventive strategies. (nih.gov)
- This article reviews the current knowledge of postmortem toxicology of synthetic opioids and the chemical and pharmacological factors that may affect drug concentrations in the different postmortem matrices and therefore, their interpretation. (nih.gov)
Characteristics1
- Therefore, pHu may be used to predict beef tenderness and other quality characteristics during postmortem ageing. (hindawi.com)
Data3
- o Efforts to compare postmortem data across different studies and protocols. (nih.gov)
- As a result, this case has two major implications: 1) data hosts (e.g., website hosts and social media platforms) may need to revise their Terms of Service Agreements to further address how they will protect customer data, and 2) estate planners should carefully consider their clients' postmortem data privacy interests. (hklaw.com)
- RATs has been evaluated extensively in clinics (2-4), pathogenic avian influenza A(H5N8) virus in wild migratory data on postmortem testing are still lacking (5). (cdc.gov)
Life1
- Medical examiners, coroners, and other healthcare professionals should use professional judgment to determine if a decedent had signs and symptoms compatible with COVID-19 during life and whether postmortem testing is necessary. (cdc.gov)
Service1
- A postmortem is an important step in the lifecycle of an always-on service. (atlassian.com)
Review2
- The best way to work through what happened during an incident and capture any lessons learned is by conducting an incident postmortem, also known as a post-incident review. (atlassian.com)
- They conducted a literature review on postmortem genetic testing and evaluated the financial impact of such testing on downstream costs for families. (mit.edu)
Studies2
- Postmortem studies allow researchers to determine causes and cure for certain diseases and functions. (wikipedia.org)
- Postmortem studies allows for researchers to give information that is relevant to individuals by explaining the causes of particular diseases and behaviors. (wikipedia.org)
Place1
- This ensures that the critical remediation work identified in the postmortem finds a place in upcoming work and is balanced against other upcoming work and priorities. (atlassian.com)
Quality1
- This paper describes the complex effects of postmortem ultimate pH (pHu) on Chinese Yellow crossbreed cattle quality during postmortem ageing and provides an explanation of how pHu affects beef tenderness. (hindawi.com)
Procedures1
- These clips from training films show some of the procedures of postmortem examination. (nih.gov)
Impact1
- An incident postmortem brings people together to discuss the details of an incident: why it happened, its impact, what actions were taken to mitigate it and resolve it, and what should be done to prevent it from happening again. (atlassian.com)
Important1
- Perinatal postmortems: What is important to parents and how do they decide? (wikipedia.org)
Lead1
- The work revealed strong financial incentive for payers to cover the cost of postmortem genetic testing in the United States, since postmortem genetic testing after SCD can lead to meaningful cost savings in most cases. (mit.edu)
Virus1
- Maintained infectivity is supported by virus iso- indicated by Spearman correlation of 79 matched da- lation up to 35 hours postmortem. (cdc.gov)
Greater1
- Greater stress should be placed on the postmortem examination in selected cases rather than in a fixed percentage of deaths. (nih.gov)