Infections with bacteria of the genus PSEUDOMONAS.
A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in nature. Some species are pathogenic for humans, animals, and plants.
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Substances that reduce the growth or reproduction of BACTERIA.
A species of gram-negative, aerobic bacteria isolated from soil and water as well as clinical specimens. Occasionally it is an opportunistic pathogen.
A species of nonpathogenic fluorescent bacteria found in feces, sewage, soil, and water, and which liquefy gelatin.
A species of gram-negative, fluorescent, phytopathogenic bacteria in the genus PSEUDOMONAS. It is differentiated into approximately 50 pathovars with different plant pathogenicities and host specificities.
Viruses whose host is Pseudomonas. A frequently encountered Pseudomonas phage is BACTERIOPHAGE PHI 6.
A species of gram-negative bacteria in the genus PSEUDOMONAS, containing multiple genomovars. It is distinguishable from other pseudomonad species by its ability to use MALTOSE and STARCH as sole carbon and energy sources. It can degrade ENVIRONMENTAL POLLUTANTS and has been used as a model organism to study denitrification.
Proteins found in any species of bacterium.

Clindamycin plus gentamicin as expectant therapy for presumed mixed infections. (1/3200)

The prevalence of obligate anaerobes was studied prospectively in 60 patients with severe sepsis of intra-abdominal, soft tissue, female genital or oropulmonary origin. In addition, the efficacy of clindamycin (for anaerobes) plus gentamicin (for aerobic bacteria, especially coliforms) as initial empiric therapy in these patients was evaluated. Among 54 patients with cultural proof of infection, anaerobic pathogens were recovered from 52%. Nineteen patients had bacteremia; Bacteroides fragilis and Klebsiella pneumoniae were the most prevalent pathogens, being isolated in five patients each. Infection was eradicated in 56 of the 60 patients (93%). Mortality related to sepsis was 7% in the entire group, 16% in patients with bacteremia and 2% in patients without bacteremia. Eighty-five percent of aerobic isolates tested were susceptible in vitro to either gentamicin or clindamycin; 97% of anaerobic isolates were inhibited by 5 mug/ml of clindamycin.  (+info)

Route and type of nutrition influence mucosal immunity to bacterial pneumonia. (2/3200)

OBJECTIVE: To develop a model of established respiratory immunity against Pseudomonas aeruginosa pneumonia and to investigate the effects of route and type of nutrition on this immunity. SUMMARY BACKGROUND DATA: Diet influences the ability of gut-associated lymphoid tissue (GALT) to maintain mucosal immunity. Complex enteral diets and chow maintain normal GALT populations against established IgA-mediated antiviral respiratory immunity. Both intravenous and intragastric total parenteral nutrition (TPN) produce GALT atrophy, but only intragastric TPN preserves established antiviral immunity. The authors hypothesized that both GALT-depleting diets (intragastric and intravenous TPN) would impair immunity against bacterial pneumonia. METHODS: P. aeruginosa was administered intratracheally to determine the mortality rate at increasing doses, and liposomes containing P. aeruginosa antigens were used to generate effective respiratory immunization. In the final experiment, mice received liposomes containing P. aeruginosa antigens to establish immunity and then were randomized to chow, complex enteral diets, intragastric TPN, or intravenous TPN. After 5 days of diet, mice received live intratracheal P. aeruginosa, and the death rate was recorded at 24 and 48 hours. RESULTS: The LD50 and LD100 were 9 x 10(7) and 12 x 10(7), respectively. Immunization reduced the mortality rate from 66% to 12%. This immunization was maintained in mice fed chow or a complex enteral diet and was lost in animals receiving intravenous TPN. Intragastric TPN partially preserved this respiratory immunity. CONCLUSIONS: Protection against bacterial pneumonia can be induced by prior antigenic immunization. This protection is lost with intravenous TPN, partially preserved with a chemically defined enteral diet, and completely preserved with chow or complex enteral diets. Both route and type of nutrition influence antibacterial respiratory tract immunity.  (+info)

Cystic fibrosis transmembrane conductance regulator-mediated corneal epithelial cell ingestion of Pseudomonas aeruginosa is a key component in the pathogenesis of experimental murine keratitis. (3/3200)

Previous findings indicate that the cystic fibrosis transmembrane conductance regulator (CFTR) is a ligand for Pseudomonas aeruginosa ingestion into respiratory epithelial cells. In experimental murine keratitis, P. aeruginosa enters corneal epithelial cells. We determined the importance of CFTR-mediated uptake of P. aeruginosa by corneal cells in experimental eye infections. Entry of noncytotoxic (exoU) P. aeruginosa into human and rabbit corneal cell cultures was inhibited with monoclonal antibodies and peptides specific to CFTR amino acids 108 to 117. Immunofluorescence microscopy and flow cytometry demonstrated CFTR in the intact murine corneal epithelium, and electron microscopy showed that CFTR binds to P. aeruginosa following corneal cell ingestion. In experimental murine eye infections, multiple additions of 5 nM CFTR peptide 103-117 to inocula of either cytotoxic (exoU+) or noncytotoxic P. aeruginosa resulted in large reductions in bacteria in the eye and markedly lessened eye pathology. Compared with wild-type C57BL/6 mice, heterozygous DeltaF508 Cftr mice infected with P. aeruginosa had an approximately 10-fold reduction in bacterial levels in the eye and consequent reductions in eye pathology. Homozygous DeltaF508 Cftr mice were nearly completely resistant to P. aeruginosa corneal infection. CFTR-mediated internalization of P. aeruginosa by buried corneal epithelial cells is critical to the pathogenesis of experimental eye infection, while in the lung, P. aeruginosa uptake by surface epithelial cells enhances P. aeruginosa clearance from this tissue.  (+info)

The sialylation of bronchial mucins secreted by patients suffering from cystic fibrosis or from chronic bronchitis is related to the severity of airway infection. (4/3200)

Bronchial mucins were purified from the sputum of 14 patients suffering from cystic fibrosis and 24 patients suffering from chronic bronchitis, using two CsBr density-gradient centrifugations. The presence of DNA in each secretion was used as an index to estimate the severity of infection and allowed to subdivide the mucins into four groups corresponding to infected or noninfected patients with cystic fibrosis, and to infected or noninfected patients with chronic bronchitis. All infected patients suffering from cystic fibrosis were colonized by Pseudomonas aeruginosa. As already observed, the mucins from the patients with cystic fibrosis had a higher sulfate content than the mucins from the patients with chronic bronchitis. However, there was a striking increase in the sialic acid content of the mucins secreted by severely infected patients as compared to noninfected patients. Thirty-six bronchial mucins out of 38 contained the sialyl-Lewis x epitope which was even expressed by subjects phenotyped as Lewis negative, indicating that at least one alpha1,3 fucosyltransferase different from the Lewis enzyme was involved in the biosynthesis of this epitope. Finally, the sialyl-Lewis x determinant was also overexpressed in the mucins from severely infected patients. Altogether these differences in the glycosylation process of mucins from infected and noninfected patients suggest that bacterial infection influences the expression of sialyltransferases and alpha1,3 fucosyltransferases in the human bronchial mucosa.  (+info)

Cellular fatty acids and metabolic products of Pseudomonas species obtained from clinical specimens. (5/3200)

The cellular fatty acid composition of 112 reference strains and clinical isolates of Pseudomonas species was determined by gas-liquid chromatography (GLC). The presence and relative amounts of cyclopropane, hydroxy, and branched-chain fatty acids were distinguishing features of these strains. Determination of short-chain fatty acids extracted from spent growth media provided an additional means for identifying some strains. Our results show that clinical isolates of pseudomonads can be divided into eight distinct GLC groups. The procedures were especially useful for distinguishing glucose-nonoxidizing pseudomonads, which are difficult to identify by conventional criteria. Since the GLC procedures are simple, rapid, and highly reproducible, they are useful in diagnostic laboratories that process large numbers of cultures. Coupled with selected conventional tests, the analysis of short-chain and cellular fatty acids can be very useful for rapid screening of clinical isolates of Pseudomonas species.  (+info)

Pathogenesis of experimental Pseudomonas keratitis in the guinea pig: bacteriologic, clinical, and microscopic observations. (6/3200)

Uniformly severe corneal infections were produced in guinea pigs by intracorneal injection of about 10 viable Pseudomonas aeruginosa. After a brief lag period, multiplication of bacteria was rapid, reaching geometric means of 280,000 after 24 hr and of 5 million after 48 hr. Within 8 hr after inoculation, polymorphonuclear leukocytes (PMNs) began to infiltrate the anterior two thirds of the stroma. Stromal cells adjacent to the injection site became necrotic and appeared to be engulfed by PMNs. By 14 to 16 hr, an abscess containing a dense aggregate of PMNs and multiplying bacteria developed in the central stroma. By 16 to 24 hr, collagen breakdown was apparent within and around the abscess. Ultrastructural evidence of collagen breakdown included loss of intact collagen fibrils, tactoid formation, and accumulation of amorphous electron-dense material. The area of liquefactive necrosis gradually enlarged, and many corneas perforated after 3 to 4 days. Because the course of infection is highly reproducible, this model should prove useful for many studies of experimental Pseudomonas keratitis.  (+info)

Bacteriologic cure of experimental Pseudomonas keratitis. (7/3200)

Two long-term therapy trials with high concentrations of antibiotic were carried out to determine the duration of therapy required to achieve bacteriologic cure of experimental Pseudomonas keratitis in guinea pigs. In the first study, corneas still contained Pseudomonas after 4 days of continual topical therapy with either tobramycin 400 mg/ml, amikacin 250 mg/ml, ticarcillin 400 mg/ml, or carbenicillin 400 mg/ml. In an 11-day trial of topical therapy with tobramycin 20 mg/ml, 34 of 36 corneas grew no Pseudomonas after 6 or more days of therapy. The bacteriologic response to therapy in this model occurred in two phases. About 99.9% or more of the organisms in the cornea were killed in the first 24 hr of therapy. The numbers of bacteria remaining in the cornea declined gradually over the next several days until the corneas were sterile. Optimal antibiotic therapy may include two stages: initial intensive therapy with high concentrations of antibiotic applied frequently to achieve a large rapid decrease in numbers of organisms in the cornea, followed by prolonged, less intensive therapy to eradicate organisms and prevent relapse.  (+info)

Comparison of flagellin genes from clinical and environmental Pseudomonas aeruginosa isolates. (8/3200)

Pseudomonas aeruginosa, an important opportunistic pathogen, was isolated from environmental samples and compared to clinically derived strains. While P. aeruginosa was isolated readily from an experimental mushroom-growing unit, it was found only rarely in other environmental samples. A flagellin gene PCR-restriction fragment length polymorphism analysis of the isolates revealed that environmental and clinical P. aeruginosa strains are not readily distinguishable. The variation in the central regions of the flagellin genes of seven of the isolates was investigated further. The strains used included two strains with type a genes (998 bp), four strains with type b genes (1,258 bp), and one strain, K979, with a novel flagellin gene (2,199 bp). The route by which flagellin gene variation has occurred in P. aeruginosa is discussed.  (+info)

Pseudomonas infections are infections caused by the bacterium Pseudomonas aeruginosa or other species of the Pseudomonas genus. These bacteria are gram-negative, opportunistic pathogens that can cause various types of infections, including respiratory, urinary tract, gastrointestinal, dermatological, and bloodstream infections.

Pseudomonas aeruginosa is a common cause of healthcare-associated infections, particularly in patients with weakened immune systems, chronic lung diseases, or those who are hospitalized for extended periods. The bacteria can also infect wounds, burns, and medical devices such as catheters and ventilators.

Pseudomonas infections can be difficult to treat due to the bacteria's resistance to many antibiotics. Treatment typically involves the use of multiple antibiotics that are effective against Pseudomonas aeruginosa. In severe cases, intravenous antibiotics or even hospitalization may be necessary.

Prevention measures include good hand hygiene, contact precautions for patients with known Pseudomonas infections, and proper cleaning and maintenance of medical equipment.

"Pseudomonas aeruginosa" is a medically important, gram-negative, rod-shaped bacterium that is widely found in the environment, such as in soil, water, and on plants. It's an opportunistic pathogen, meaning it usually doesn't cause infection in healthy individuals but can cause severe and sometimes life-threatening infections in people with weakened immune systems, burns, or chronic lung diseases like cystic fibrosis.

P. aeruginosa is known for its remarkable ability to resist many antibiotics and disinfectants due to its intrinsic resistance mechanisms and the acquisition of additional resistance determinants. It can cause various types of infections, including respiratory tract infections, urinary tract infections, gastrointestinal infections, dermatitis, and severe bloodstream infections known as sepsis.

The bacterium produces a variety of virulence factors that contribute to its pathogenicity, such as exotoxins, proteases, and pigments like pyocyanin and pyoverdine, which aid in iron acquisition and help the organism evade host immune responses. Effective infection control measures, appropriate use of antibiotics, and close monitoring of high-risk patients are crucial for managing P. aeruginosa infections.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to form a cell wall, which is necessary for their survival. This causes the bacterial cells to become unstable and eventually die. Carbenicillin is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, and is often used to treat serious infections caused by these organisms. It is administered orally or intravenously, depending on the type and severity of the infection being treated.

Carbenicillin is a type of antibiotic known as a penicillin. It works by interfering with the ability of bacteria to

"Pseudomonas" is a genus of Gram-negative, rod-shaped bacteria that are widely found in soil, water, and plants. Some species of Pseudomonas can cause disease in animals and humans, with P. aeruginosa being the most clinically relevant as it's an opportunistic pathogen capable of causing various types of infections, particularly in individuals with weakened immune systems.

P. aeruginosa is known for its remarkable ability to resist many antibiotics and disinfectants, making infections caused by this bacterium difficult to treat. It can cause a range of healthcare-associated infections, such as pneumonia, bloodstream infections, urinary tract infections, and surgical site infections. In addition, it can also cause external ear infections and eye infections.

Prompt identification and appropriate antimicrobial therapy are crucial for managing Pseudomonas infections, although the increasing antibiotic resistance poses a significant challenge in treatment.

Cystic fibrosis (CF) is a genetic disorder that primarily affects the lungs and digestive system. It is caused by mutations in the CFTR gene, which regulates the movement of salt and water in and out of cells. When this gene is not functioning properly, thick, sticky mucus builds up in various organs, leading to a range of symptoms.

In the lungs, this mucus can clog the airways, making it difficult to breathe and increasing the risk of lung infections. Over time, lung damage can occur, which may lead to respiratory failure. In the digestive system, the thick mucus can prevent the release of digestive enzymes from the pancreas, impairing nutrient absorption and leading to malnutrition. CF can also affect the reproductive system, liver, and other organs.

Symptoms of cystic fibrosis may include persistent coughing, wheezing, lung infections, difficulty gaining weight, greasy stools, and frequent greasy diarrhea. The severity of the disease can vary significantly among individuals, depending on the specific genetic mutations they have inherited.

Currently, there is no cure for cystic fibrosis, but treatments are available to help manage symptoms and slow the progression of the disease. These may include airway clearance techniques, medications to thin mucus, antibiotics to treat infections, enzyme replacement therapy, and a high-calorie, high-fat diet. Lung transplantation is an option for some individuals with advanced lung disease.

Gentamicin is an antibiotic that belongs to the class of aminoglycosides. It is used to treat various types of bacterial infections, including:

* Gram-negative bacterial infections, such as those caused by Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis
* Certain Gram-positive bacterial infections, such as those caused by Staphylococcus aureus and Streptococcus pyogenes

Gentamicin works by binding to the 30S subunit of the bacterial ribosome, which inhibits protein synthesis and ultimately leads to bacterial cell death. It is typically given via injection (intramuscularly or intravenously) and is often used in combination with other antibiotics to treat serious infections.

Like all aminoglycosides, gentamicin can cause kidney damage and hearing loss, especially when used for long periods of time or at high doses. Therefore, monitoring of drug levels and renal function is recommended during treatment.

Anti-bacterial agents, also known as antibiotics, are a type of medication used to treat infections caused by bacteria. These agents work by either killing the bacteria or inhibiting their growth and reproduction. There are several different classes of anti-bacterial agents, including penicillins, cephalosporins, fluoroquinolones, macrolides, and tetracyclines, among others. Each class of antibiotic has a specific mechanism of action and is used to treat certain types of bacterial infections. It's important to note that anti-bacterial agents are not effective against viral infections, such as the common cold or flu. Misuse and overuse of antibiotics can lead to antibiotic resistance, which is a significant global health concern.

"Pseudomonas putida" is a species of gram-negative, rod-shaped bacteria that is commonly found in soil and water environments. It is a non-pathogenic, opportunistic microorganism that is known for its versatile metabolism and ability to degrade various organic compounds. This bacterium has been widely studied for its potential applications in bioremediation and industrial biotechnology due to its ability to break down pollutants such as toluene, xylene, and other aromatic hydrocarbons. It is also known for its resistance to heavy metals and antibiotics, making it a valuable tool in the study of bacterial survival mechanisms and potential applications in bioremediation and waste treatment.

"Pseudomonas fluorescens" is a gram-negative, rod-shaped bacterium found in various environments such as soil, water, and some plants. It is a non-pathogenic species of the Pseudomonas genus, which means it does not typically cause disease in humans. The name "fluorescens" comes from its ability to produce a yellow-green pigment that fluoresces under ultraviolet light. This bacterium is known for its versatility and adaptability, as well as its ability to break down various organic compounds, making it useful in bioremediation and other industrial applications.

"Pseudomonas syringae" is a gram-negative, aerobic bacterium that is widely found in various environments, including water, soil, and plant surfaces. It is known to be a plant pathogen, causing diseases in a wide range of plants such as beans, peas, tomatoes, and other crops. The bacteria can infect plants through wounds or natural openings, leading to symptoms like spots on leaves, wilting, and dieback. Some strains of "P. syringae" are also associated with frost damage on plants, as they produce a protein that facilitates ice crystal formation at higher temperatures.

It's important to note that while "Pseudomonas syringae" can cause disease in plants, it is not typically considered a human pathogen and does not usually cause illness in humans.

Pseudomonas phages are viruses that infect and replicate within bacteria of the genus Pseudomonas. These phages are important in the study of Pseudomonas species, which include several significant human pathogens such as P. aeruginosa. Phages can be used for therapeutic purposes to treat bacterial infections, including those caused by Pseudomonas. Additionally, they are also useful tools in molecular biology and genetic research.

It's worth noting that while "Pseudomonas phages" refers specifically to phages that infect Pseudomonas bacteria, the term "phage" on its own is used to describe any virus that infects and replicates within a bacterial host.

"Pseudomonas stutzeri" is a gram-negative, rod-shaped bacterium that is widely found in various environments such as soil, water, and plants. It is a non-fermentative, motile bacterium that can survive in diverse conditions due to its metabolic versatility. While it is not typically considered a human pathogen, there have been reports of P. stutzeri causing infections in immunocompromised individuals or those with underlying medical conditions. These infections can include respiratory tract infections, urinary tract infections, and bacteremia. However, such cases are relatively rare, and the bacterium is generally considered to have low pathogenic potential for humans.

Bacterial proteins are a type of protein that are produced by bacteria as part of their structural or functional components. These proteins can be involved in various cellular processes, such as metabolism, DNA replication, transcription, and translation. They can also play a role in bacterial pathogenesis, helping the bacteria to evade the host's immune system, acquire nutrients, and multiply within the host.

Bacterial proteins can be classified into different categories based on their function, such as:

1. Enzymes: Proteins that catalyze chemical reactions in the bacterial cell.
2. Structural proteins: Proteins that provide structural support and maintain the shape of the bacterial cell.
3. Signaling proteins: Proteins that help bacteria to communicate with each other and coordinate their behavior.
4. Transport proteins: Proteins that facilitate the movement of molecules across the bacterial cell membrane.
5. Toxins: Proteins that are produced by pathogenic bacteria to damage host cells and promote infection.
6. Surface proteins: Proteins that are located on the surface of the bacterial cell and interact with the environment or host cells.

Understanding the structure and function of bacterial proteins is important for developing new antibiotics, vaccines, and other therapeutic strategies to combat bacterial infections.

... refers to a disease caused by one of the species of the genus Pseudomonas. P. aeruginosa is a germ found ... Wikimedia Commons has media related to Pseudomonas infections. Elkin S, Geddes D (2003). "Pseudomonal infection in cystic ... Infection can affect many parts of the body, but infections typically target the respiratory tract, the renal system, the ... Obritsch; Fish; MacLauren; Jung (2005). "Nosocomial Infections Due to Multidrug-Resistant Pseudomonas aeruginosa: Epidemiology ...
"What Is a Pseudomonas Infection?". MedicineNet. Retrieved 8 December 2020. "Pseudomonas aeruginosa in Healthcare Settings". ... On the rare occasions where infection is superficial and limited (for example, ear infections or nail infections), topical ... Pseudomonas is also a common cause of postoperative infection in radial keratotomy surgery patients. The organism is also ... "Pseudomonas aeruginosa in Healthcare Settings". Healthcare-associated Infections (HAI): Diseases and Organisms. Centers for ...
It can be caused by infection, particularly from Pseudomonas species, such as Pseudomonas aeruginosa, Clostridium species, ... Bodey, G. P.; Bolivar, R.; Fainstein, V.; Jadeja, L. (1983). "Infections Caused by Pseudomonas aeruginosa". Clinical Infectious ... and ecthyma gangrenosum in an immunocompromised host with pseudomonas septicemia". American Journal of Ophthalmology. 137 (1): ...
Spernovasilis N, Psichogiou M, Poulakou G (April 2021). "Skin manifestations of Pseudomonas aeruginosa infections". Curr Opin ... Qureshi S, Bronze MS (March 3, 2023). "Pseudomonas aeruginosa Infections: Clinical Presentation". eMedicine. (Use mdy dates ... Nail scrapings can be performed to rule out fungal infections. Green nails may also be seen with Proteus mirabilis infection, ... Chronic fungal infection (onychomycosis) may also be present. Green nail syndrome is caused when the nail is exposed to a ...
Gilardi GL, Mankin HJ (December 1973). "Infection due to Pseudomonas stutzeri". New York State Journal of Medicine. 73 (23): ... Since that initial infection, P. stutzeri has been able to cause infections within individuals that have a variety of illnesses ... All Pseudomonas bacteria were originally thought to be incapable of fixing nitrogen. Several Pseudomonas species, including P. ... among the Pseudomonas Major Evolutionary Groups Reveals Species-Specific Adaptations for Pseudomonas aeruginosa and Pseudomonas ...
Pseudomonas aeruginosa is an unusual agent to cause a urinary tract infection which appeared to have caused the sepsis. Later ... "Brazilian Model Dies of Pseudomonas Infection". Newsarticle. medHeadlines.com. 2009-01-24. Archived from the original on 2013- ... she was diagnosed with a urinary tract infection that worsened to become septic shock caused by a bacterial infection, probably ... The cause of death according to the hospital certificate was a severe sepsis, urinary infection and abdominal bleeding which ...
HACEK Group Infections at eMedicine "Pseudomonas aeruginosa". Topics in Infectious Diseases Newsletter. August 2001. Archived ... The cause is typically a bacterial infection and less commonly a fungal infection. Risk factors include valvular heart disease ... Pseudomonas species, which are very resilient organisms that thrive in water, may contaminate street drugs that have been ... In rheumatic heart disease, infection occurs on the aortic and the mitral valves on the left side of the heart.[citation needed ...
Harrison F, Browning LE, Vos M, Buckling A (July 2006). "Cooperation and virulence in acute Pseudomonas aeruginosa infections ... Infection leads to inflammation and the release of interleukin-6 (IL-6 ) which stimulates hepcidin expression. In humans, IL-6 ... In a recent study, the production of pyoverdine (PVD), a type of siderophore, in the bacterium Pseudomonas aeruginosa has been ... With bacterial vascular diseases, the infection is spread within the plants through the xylem. Once within the plant, the ...
Nosocomial infection MRSA VRE Pseudomonas aeruginosa Butler, M; Olson, A; Drekonja, D; Shaukat, A; Schwehr, N; Shippee, N; Wilt ... used in healthcare environments to control the spread of infections. Nosocomial infections claim approximately 90,000 lives in ... When patients are hospitalized and identified as having methicillin-resistant Staphylococcus aureus or infections that can be ... cite journal}}: Cite journal requires ,journal= (help) "Cleaning & disinfection". The Northern Ireland Regional Infection ...
Lau G, Hassett D, Ran H, Kong F (2004). "The role of pyocyanin in Pseudomonas aeruginosa infection". Trends in Molecular ... Pseudomonas aeruginosa Pyoverdine Cystic fibrosis Pyocyanin at Sigma-Aldrich Hassan H, Fridovich I (1980). "Mechanism of the ... Hassett D, Woodruff W, Wozniak D, Vasil M, Cohen S, Ohman D (1993). "Cloning and characterization of the Pseudomonas aeruginosa ... Kerr J, Taylor G, Rutman A, Hoiby N, Cole P, Wilson R (1998). "Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine inhbit ...
January 2013). "Multifunctional Role of Human SPLUNC1 in Pseudomonas aeruginosa Infection". Infection and Immunity. 81 (1): 285 ... May 2013). "SPLUNC1/BPIFA1 Contributes to Pulmonary Host Defense against Klebsiella pneumoniae Respiratory Infection". The ... makes bacteria like Pseudomonas more permeable, and attracts macrophages and neutrophils for a bactericidal effect. As such, ... "Effect of SPLUNC1 protein on the Pseudomonas aeruginosa and Epstein-Barr virus". Molecular and Cellular Biochemistry. 309 (1-2 ...
Davies leads the Strategic Research Centre for Pseudomonas Infection in Cystic Fibrosis at Imperial College London, one of few ... "Strategic Research Centre for Pseudomonas Infection in Cystic Fibrosis". Imperial College London. Retrieved 2019-02-25. " ... The centre looks to identify new ways to detect pseudomonas aeruginosa. Davies is part of the European CF Society Clinical ... "Strategic Research Centre: Pseudomonas". cysticfibrosis.org.uk. Retrieved 2019-02-25. "Professor Jane Davies recognised with ...
Lau GW; Hassett DJ; Ran H; Kong F (2004). "The role of pyocyanin in Pseudomonas aeruginosa infection". Trends in Molecular ... Pseudomonas at origin of world's rain and snow Pseudomonas survive in nuclear reactor Pseudomonas genome database Pseudomonas ... Pseudomonas phage Φ6 Pseudomonas phage ΦCTX Pseudomonas aeruginosa phage EL Pseudomonas aeruginosa phage ΦKMV (a Phikmvvirus) ... Pseudomonas aeruginosa phage LUZ19 (a Phikmvvirus) Pseudomonas aeruginosa phage ΦKZ Pseudomonas putida phage gh-1 Culture ...
"Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection". Nature Microbiology. 4 (12): 2146-2154. doi: ... Ribbeck's work has also demonstrated the role of mucus in protecting against fungal infections. Her studies have shown that ... She has shown that mucins prevent bacteria such as Pseudomonas aeruginosa and Streptococcus mutans, the bacteria that cause ... Ribbeck demonstrated that mucin glycans can reduce the virulence of pathogens such as Pseudomonas aeruginosa, a bacterium that ...
Koike, K (Dec 1976). "Protective effect of schizophyllan on Pseudomonas aeruginosa infection of mouse". Japanese Journal of ... Itoh, W (1997). "Augemtnation of protective immune responses against viral infection by oral administration of schizophyllan". ... "Augemtnation of protective immune responses against Sendai virus infection by fungal polysaccharide schizophyllan". ...
Pseudomonas aeruginosa is a bacterium that can cause respiratory infections. It is frequently associated with cystic fibrosis ... An opportunistic infection is an infection caused by pathogens (bacteria, fungi, parasites or viruses) that take advantage of ... Since opportunistic infections can cause severe disease, much emphasis is placed on measures to prevent infection. Such a ... Opportunistic infections caused by feline leukemia virus and feline immunodeficiency virus retroviral infections can be treated ...
One specific research topic of interest is how microbes such as Pseudomonas aeruginosa invade the eye and cause infection. ... This might partly explain why Pseudomonas infections are the most predominant. However, another study conducted with worn and ... Other lenses need regular cleaning and disinfecting to prevent surface coating and infections. There are many ways to clean and ... Corneal abrasions can increase the chances of infection. When combined with improper cleaning and disinfection of the lens, a ...
"Role of Iron Uptake Systems in Pseudomonas aeruginosa Virulence and Airway Infection". Infection and Immunity. 84 (8): 2324- ... "Impact of siderophore production on Pseudomonas aeruginosa infections in immunosuppressed mice". Infection and Immunity. 68 (4 ... 1882: Pseudomonas aeruginosa grown for first time in pure culture by Carle Gessard, reported in "On the Blue and Green ... In Pseudomonas aeruginosa PAO1 there are 14 pvd genes involved in the biosynthesis of pyoverdine. Pyoverdine biosynthesis seems ...
Rybtke M, Hultqvist LD, Givskov M, Tolker-Nielsen T (November 2015). "Pseudomonas aeruginosa Biofilm Infections: Community ... urinary tract infections, catheter infections, middle-ear infections, formation of dental plaque, gingivitis, coating contact ... Examples of such infections include chronic wounds, chronic otitis media, chronic prostatitis and chronic lung infections in ... Biofilms of fungal origin are important aspects of human infection and fungal pathogenicity, as the fungal infection is more ...
"Murine ocular heparanase expression before and during infection with Pseudomonas aeruginosa". Invest Ophthalmol Vis Sci. 45 (4 ... Tear lacritin monomer is barely detectable in the initial stage of infection by Fusarium solani in fungal keratitis. Also down ...
"Pseudomonas Aeruginosa Bloodstream Infection at A Tertiary Referral Hospital For Children". www.researchsquare.com. 10 July ...
"Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species". Proceedings of the National Academy ... Tzou, Phoebe; De Gregorio, Ennio; Lemaitre, Bruno (2002-02-01). "How Drosophila combats microbial infection: a model to study ... uses genetic screens as tools to identify novel factors involved in the immune response following microbial infection. His team ...
"Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa infection". Nature Protocols. 4 (9): 1285-94. doi: ... Using plants as a model host to study Pseudomonas aeruginosa pathogenicity led her and her colleagues to develop multi-host ... Rahme is best known for her pioneering work on Pseudomonas aeruginosa, demonstrating for the first time that this bacterium ... Her work in host-pathogen interactions continues to inspire researchers in developing novel ways to fight infections. Her group ...
Gallium compounds are active against infection-related biofilms, particularly those caused by Pseudomonas aeruginosa. In ... "Gallium maltolate treatment eradicates Pseudomonas aeruginosa infection in thermally injured mice". Antimicrobial Agents and ... "The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity". J ... "Characterization of gallium resistance induced in a Pseudomonas aeruginosa cystic fibrosis isolate". Archives of Microbiology. ...
"Surfactant protein-A-deficient mice are susceptible to Pseudomonas aeruginosa infection". American Journal of Respiratory Cell ... This research has shown that mice deficient in SP-A are more susceptible to infections from group B Streptoccoal organisms, ... Pseudomonas aeruginosa, and likely other organisms. The immune functions of SP-A are time, temperature, and concentration ... "Surfactant protein A-deficient mice are susceptible to group B streptococcal infection". Journal of Immunology. 158 (9): 4336- ...
"Evolution of antibiotic tolerance shapes resistance development in chronic Pseudomonas aeruginosa infections". mBio. 12 (1). ... most recent work has investigated the importance of signalling and metabolism for chronic lung infections caused by Pseudomonas ... "LadS is a calcium-responsive kinase that induces acute-to-chronic virulence switch in Pseudomonas aeruginosa". Nature ... "A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa". Cell Host & Microbe. 25 (1): 140- ...
Green, foul-smelling pus is found in certain infections of Pseudomonas aeruginosa. The greenish color is a result of the ... During infection, T helper cells release cytokines, which trigger neutrophils to seek the site of infection by chemotaxis. ... Oral and maxillofacial infections (4 ed.). Philadelphia: W.B. Saunders. ISBN 978-0721692715. "Infections Caused by Common ... Barer, M.R. (2012). "The natural history of infection". Medical Microbiology. Elsevier. pp. 168-173. doi:10.1016/b978-0-7020- ...
Ong DS, Wang L, Zhu Y, Ho B, Ding JL (2005). "The response of ferritin to LPS and acute phase of Pseudomonas infection". ... However it is less sensitive, since its levels are increased in the blood by infection or any type of chronic inflammation, and ... For example, ferritins may be high in infection without signaling body iron overload. Ferritin is also used as a marker for ... Ferritin concentrations increase drastically in the presence of an infection or cancer. Endotoxins are an up-regulator of the ...
McVay CS, Velásquez M, Fralick JA (June 2007). "Phage therapy of Pseudomonas aeruginosa infection in a mouse burn wound model ... Phages were used successfully at Yale University by Benjamin Chan to treat a Pseudomonas infection in 2016. Intravenous phage ... Phage therapy is being used to great effect in the treatment of biofilm infections, especially Pseudomonas aeruginosa and ... March 2017). "Synergistic Interaction Between Phage Therapy and Antibiotics Clears Pseudomonas Aeruginosa Infection in ...
Liong, Edgard; Hammond, D. D.; Vedros, Neylan A. (1985). "Pseudomonas pseudomallei infection in a dolphin (Tursiops gilli): A ...
She is known for her research on bacterial infections caused by Pseudomonas aeruginosa. Kalai Mathee was born into a working- ... Since 1993, the major focus of Mathee's research has been the pathobiology of Pseudomonas aeruginosa chronic infections with ... Mathee has examined the role of quorum sensing molecules in Pseudomonas aeruginosa infections, and demonstrated that alginate ... "Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection". Microbiology ...
... used against certain life-threatening infections, such as those caused by Pseudomonas; carries risk of kidney and nerve damage ... used as a drug of last resort for a variety of different bacterial infections; Ceftobiprole and ceftaroline - fifth-generation ... a cephalosporin used to treat complicated urinary tract infections (cUTI) caused by multi-drug resistant Gram-negative bacteria ... used for life-threatening fungal infections and primary amoebic meningoencephalitis; its side effects are often severe or ...
"Pf Bacteriophage and Their Impact on Pseudomonas Virulence, Mammalian Immunity, and Chronic Infections". Frontiers in ... of ICTV's species Pseudomonas virus Pf1 of genus Primolicivirus), and perhaps also Pf3 (of ICTV's species Pseudomonas virus Pf3 ... species Pseudomonas virus Pf1 Pf1 phage genus Tertilicivirus) species Pseudomonas virus Pf3 - bacteriophages that infect ... The two ends of the phage are capped by a few copies of proteins that are important for infection of the host bacteria, and ...
Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas. P. aeruginosa is a germ found ... Wikimedia Commons has media related to Pseudomonas infections. Elkin S, Geddes D (2003). "Pseudomonal infection in cystic ... Infection can affect many parts of the body, but infections typically target the respiratory tract, the renal system, the ... Obritsch; Fish; MacLauren; Jung (2005). "Nosocomial Infections Due to Multidrug-Resistant Pseudomonas aeruginosa: Epidemiology ...
Gessard first discovered Pseudomonas, a strictly aerobic, gram-negative bacterium of relatively low virulence. The organism is ... encoded search term (Pseudomonas Infection) and Pseudomonas Infection What to Read Next on Medscape ... Life-threatening Pseudomonas aeruginosa infections in patients with human immunodeficiency virus infection. Clin Infect Dis. ... Pseudomonas Infections in Children with Human Immunodeficiency Virus Infection. Pediatric Infect Dis J. 1992. 11:547-53. ...
... from Pseudomonas aeruginosa on polymorphonuclear leucocytes (PMNLs) were studied in a mouse model and in vitro. P. aeruginosa ... Role of exotoxin A in inducing severe Pseudomonas aeruginosa infections in mice J Med Microbiol. 1995 Sep;43(3):169-75. doi: ... The effects of exotoxin A (EXA) from Pseudomonas aeruginosa on polymorphonuclear leucocytes (PMNLs) were studied in a mouse ... infection with strain PA103. The number of PMNLs in murine blood decreased by 50% within 30 min of intravenous injection of EXA ...
Nosocomial Infections with IMP-19−Producing Pseudomonas aeruginosa Linked to Contaminated Sinks, France Lucie Amoureux, Karena ... Nosocomial Infections with IMP-19−Producing Pseudomonas aeruginosa Linked to Contaminated Sinks, France. ... Characteristics of bacterial isolates from patients with nosocomial infections linked to contaminated sinks, France* ...
Our results with Arikace may contribute to novel utilisation of topical antibiotics to treat Pseudomonas infection in CF ... Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic ... Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection ... Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection ...
Chronic Pseudomonas aeruginosa infection in the current paediatric patients is low and agrees with the low Pseudomonas ... Høiby N. Pseudomonas aeruginosa infection in cystic fibrosis. Relationship between mucoid strains of pseudomonas aeruginosa and ... Pseudomonas aeruginosa infection in cystic fibrosis. Diagnostic and prognostic significance of Pseudomonas aeruginosa ... IgG subclass antibodies to Pseudomonas aeruginosa in sera from patients with chronic Pseudomonas aeruginosa infection ...
The effect of high soil nitrogen on gene expression in tomato during infection by Pseudomonas syringae pv. tomato DC3000 by ... Response of rice genotypes to rice rootknot nematode (Meloidogyne graminicola) infection under varying temperature regimes. ...
Antimicrobial susceptibility patterns of clinical isolates of Pseudomonas aeruginosa isolated from patients of respiratory ... tract infections in a Tertiary Care Hospital, Peshawar ...
... explains the limitations of the current drugs for the treatment of Pseudomonas aeruginosa infections. ... What are the Limitations of Current Drugs to Treat Pseudomonas Infections?. July 8, 2017. Contagion Editorial Staff ... CoronavirusAntimicrobial StewardshipBlood-Borne DiseasesFood-Borne InfectionsGastrointestinal InfectionsHealthcare-Associated ... explains the limitations of the current drugs for the treatment of Pseudomonas aeruginosa infections. ...
Pseudomonas Infections - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer ... Pseudomonas aeruginosa infections range from minor external infections to serious, life-threatening disorders. Infections occur ... Serious infections due to Pseudomonas aeruginosa are difficult to treat. Malignant external otitis, internal infections (such ... In people with HIV infection, Pseudomonas bacteria commonly cause pneumonia or sinus infections. ...
Phage infection experiments under simulated chronic lung infection conditions showed that alginate production reduces phage ... We used an artificial sputum medium to study phage infection under conditions similar to a chronic lung infection. Alginate ... However, little is known about the factors which influence phage infection of P. aeruginosa under infection conditions and ... Phage therapy is an alternative to treat these chronic P. aeruginosa infections. ...
... L. E. Tatterson1. , J. F. Poschet1. , A. Firoved1. , J. Skidmore1. , V. ... CFTR and pseudomonas infections in cystic fibrosis. Front. Biosci. (Landmark Ed) 2001, 6(3), 890-897. https://doi.org/10.2741/ ... Pseudomonas aeruginosa is a significant threat to human health as it is frequently recalcitrant to conventional antibacterial ... aeruginosa infections in CF. A major emphasis will be placed on the factors predisposing CF patients to colonization with P. ...
... is medication for infections caused by Pseudomonas aeruginosa, and other infections. ... is indicated for the treatment of infections caused by Pseudomonas aeruginosa, and also infections due to other susceptible ... In life-threatening infections particularly caused by Klebsiella spp. or Pseudomonas:. VIGOCID should be given in a dose of not ... Gynaecological infections including postpartum endometritis and pelvic inflammatory disease (PID). *Intra-abdominal infections ...
Causes and Symptoms of Pseudomonas Infections. Herbal treatment of Pseudomonas Infections by natural herbs is given in ... Most effective herbal treatment for Pseudomonas Infections and herbs for Pseudomonas Infections. ... Note: Pseudomonas Aeruginosa is the most common species that causes Pseudomonas Infections.. Causes of Pseudomonas Infections ... Pseudomonas Infections Symptoms Pseudomonas Infections Fever Chills. Discharge of Pus from the Wounds. Infection of the Ears. ...
Bacteriophages as a potential treatment for Pseudomonas aeruginosa mediated chest infections in cystic fibrosis patients.. File ... Bacteriophages as a potential treatment for Pseudomonas aeruginosa mediated chest infections in cystic fibrosis patients. ... Bacteriophages as a potential treatment for Pseudomonas aeruginosa mediated chest infections in cystic fibrosis patients. ... aeruginosa lung infection on which bacteriophage could be assessed for their efficacy as a therapeutic agent.. Date of Award. ...
Susceptibility Testing for Pseu domonas in Urinary Tract Infections. Most strains of Pseudomonas aeruginosa are moderately ... Because of the serious nature of some urinary tract infections due to P. aeruginosa and because many strains of Pseudomonas ... Because of the serious nature of urinary tract infections due to P. aeruginosa and because many strains of Pseudomonas species ... They do not treat viral infections (e.g., the common cold). When Cefizox is prescribed to treat a bacterial infection, patients ...
Interestingly, P. aeruginosa infection induced a similar level of IL-1β, IL-6 and TNF production in wild-type and AIM2- ... Lung infection with P. aeruginosa is often associated with production of various inflammatory cytokines including IL-1β. ... A role of AIM2 in P. aeruginosa infection has not been reported previously. In this study, we found that P. aeruginosa ... Our data suggest that AIM2 inflammasome is dispensable for the host defense against P. aeruginosa infection. ...
Pseudomonas Infections. 500 mg IV q6hr; higher dosages may be administered, depending on organism sensitivity ... Intra-abdominal Infections. Mild to moderate: 250-500 mg IV q6hr. Severe: 500 mg IV q6hr or 1 g q8hr for 4-7 days, provided ... Moderate infections. *IV: Fully susceptible organisms: 500 mg IV q6-8hr. *Moderately susceptible organisms: 500 mg IV q6hr or 1 ... Severe infections. *Fully susceptible organisms: 500 mg IV q6hr. *Moderately susceptible organisms: 1 g IV q6-8hr; not to ...
... which was isolated from a patient with a respiratory tract infection in Chongqing, Peoples Republic of China. Whole-genome ... We report the 6,498,072-bp complete genome sequence of Pseudomonas aeruginosa PA1, ... Complete genome sequence of Pseudomonas aeruginosa PA1, isolated from a patient with a respiratory tract infection. Authors: Lu ... We report the 6,498,072-bp complete genome sequence of Pseudomonas aeruginosa PA1, which was isolated from a patient with a ...
P. aeruginosa bacteremia is a common and severe infection carrying high mortality in older adults. We aimed to evaluate ... Pseudomonas aeruginosa Estudos de Coortes Nonagenários Octogenários Infecções por Pseudomonas/tratamento farmacológico ... Bacteriemia Infecções por Pseudomonas Masculino Idoso de 80 Anos ou mais Humanos Idoso Feminino Antibacterianos/uso terapêutico ... Outcomes of octogenarians and nonagenarians with Pseudomonas aeruginosa bacteremia: a multicenter retrospective study.. Atamna ...
Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic ... of extreme phenotypes to identify genetic variants that modify the risk for chronic Pseudomonas aeruginosa airway infection in ...
The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. In: ... The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. Plant ... The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato. / Ward ... The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato.. ...
Request a Free Sample of Pseudomonas Aeruginosa Infection Treatment Market Report: ... china Pseudomonas Aeruginosa Infection Treatment Market Pseudomonas Aeruginosa Infection Treatment Industry Pseudomonas ... Pseudomonas Aeruginosa Infection Treatment Market : Opportunities For The Industry By 2029. Pseudomonas Aeruginosa Infection ... Infection Treatment Market Pseudomonas Aeruginosa Infection Treatment Market Forecast Pseudomonas Aeruginosa Infection ...
Drosophila melanogaster as an animal model for the study of Pseudomonas aeruginosa biofilm infections in Vivo. ... Drosophila melanogaster as an animal model for the study of Pseudomonas aeruginosa biofilm infections in Vivo. Together they ...
The IL-17A/IL-17RA axis during chronic airway infection by Pseudomonas aeruginosa: Implications for host resistance and ... Recent reports prompt the hypothesis that chronic lung disease associated to persistent infections, such as Pseudomonas ... Recent reports prompt the hypothesis that chronic lung disease associated to persistent infections, such as Pseudomonas ... Blockade of IL-17 activity, by an anti-IL-17A mAb starting from ten days post-infection did not affect host resistance in terms ...
... between ceftolozane-tazobactam exposure and selection for Pseudomonas aeruginosa resistance in a hollow-fiber infection model. ... between ceftolozane-tazobactam exposure and selection for Pseudomonas aeruginosa resistance in a hollow-fiber infection model. ...
We examined this in the context of Pseudomonas aeruginosa macrophage infection, which triggers NLRC4 inflammasome activation. P ... Preventing TRIF cleavage by caspase-1 in an in vivo model of P. aeruginosa infection resulted in enhanced bacterial autophagy, ... Expression of a caspase-1 resistant TRIF mutant enhanced autophagy and type I interferon production following infection. ... NLRC4 and caspase-1 activation following infection attenuated autophagy. Caspase-1 directly cleaved TRIF to diminish TRIF- ...
  • In a surveillance study between 1986 and 1989, P. aeruginosa was the third leading cause of all nosocomial infections, and specifically the number one leading cause of hospital-acquired pneumonia and third leading cause of hospital-acquired UTI. (wikipedia.org)
  • Major trends in the microbial etiology of nosocomial infection" (PDF). (wikipedia.org)
  • Pseudomonas is a clinically significant and opportunistic pathogen, often causing nosocomial infections. (medscape.com)
  • These properties contribute to its prominence as a leading source of opportunistic nosocomial (hospital acquired) and a less appreciated, but significant cause of community acquired infections. (imrpress.com)
  • The opportunistic human pathogen Pseudomonas aeruginosa is frequently associated with nosocomial infections, and can be life threatening in immunosuppressed, cancer and cystic fibrosis patients. (nih.gov)
  • Environmental testing for IMP-19 producers in investigation of nosocomial infections linked to contaminated sinks, France. (blogspot.com)
  • Pseudomonas aeruginosa and Staphylococcus aureus causes severe infections, especially in nosocomial environments. (sasm.org.za)
  • Hospital-acquired pneumonia (HAP), or nosocomial pneumonia, is a lower respiratory infection that was not incubating at the time of hospital admission and that presents clinically 2 or more days after hospitalization. (medscape.com)
  • HAP is a common nosocomial bacterial infection and is most prevalent in medical and surgical intensive care units (ICUs). (medscape.com)
  • Because aerobic gram-negative bacilli (eg, Pseudomonas aeruginosa) are the major pathogens associated with HAP, the pathophysiology of nosocomial pneumonia relates to the destructive effect on lung tissue. (medscape.com)
  • 2] In recent years, klebsiellae have become important pathogens in nosocomial infections. (medscape.com)
  • The urinary tract is the most common site of nosocomial infection, accounting for more than 40% of the total number reported by acute-care hospitals and affecting an estimated 600,000 patients per year (1). (cdc.gov)
  • Pseudomonas aeruginosa is an opportunistic pathogen often causing nosocomial infections that are resilient to treatment due to an extensive repertoire of intrinsic and acquired resistance mechanisms. (who.int)
  • Four separate categories of chronic Pseudomonas aeruginosa ( Pa ) infection in children with cystic fibrosis (CF) have been previously defined, based on airway cultures taken over the previous year. (ersjournals.com)
  • In cystic fibrosis (CF), Pseudomonas aeruginosa ( Pa ) is the most important lung pathogen causing progressive lung infection and shortened survival 1 . (ersjournals.com)
  • Pseudomonas aeruginosa causes lung infections in patients suffering from the genetic disorder Cystic Fibrosis (CF). Once a chronic lung infection is established, P. aeruginosa cannot be eradicated by antibiotic treatment. (biomedcentral.com)
  • P. aeruginosa remains a considerable problem for patients with burns, neutropenic individuals, and cystic fibrosis patients (CF). In this review, we will address the current issues in P. aeruginosa infections in CF. A major emphasis will be placed on the factors predisposing CF patients to colonization with P. aeruginosa . (imrpress.com)
  • Bacteriophages as a potential treatment for Pseudomonas aeruginosa mediated chest infections in cystic fibrosis patients. (brighton.ac.uk)
  • Pseudomonas aeruginosa biofilm colonization is associated with declining lung function in cystic fibrosis (CF) patients. (edu.au)
  • IMPORTANCE Pseudomonas aeruginosa is a key opportunistic respiratory pathogen in patients with cystic fibrosis and non-cystic fibrosis bronchiectasis. (ncl.ac.uk)
  • image: Pseudomonas aeruginosa clumps grown in synthetic cystic fibrosis sputum. (eurekalert.org)
  • Pseudomonas aeruginosa , a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime - a common occurrence in people with cystic fibrosis. (eurekalert.org)
  • Furthermore, the ability of the pathogen to build biofilms and to persist e.g. in the lungs of cystic fibrosis (CF) patients facilitates the establishment of chronic infections, which are largely recalcitrant to antimicrobial therapies. (elifesciences.org)
  • In healthy children, disease is primarily limited to the first 2 stages (as in diseases such as otitis externa , urinary tract infections (UTIs) , dermatitis, cellulitis, and osteomyelitis ), although recent case reports describe bacteremia , sepsis , and GI infections in previously healthy children. (medscape.com)
  • It is a biofilm-forming opportunistic pathogen causing life-threatening chronic infections in immunocompromised individuals with diseases like burn wounds, urinary tract infections, and respiratory infections ( Gellatly and Hancock, 2013 ). (frontiersin.org)
  • Although not all catheter-associated urinary tract infections can be prevented, it is believed that a large number could be avoided by the proper management of the indwelling catheter. (cdc.gov)
  • Host factors which appear to increase the risk of acquiring catheter-associated urinary tract infections include advanced age, debilitation, and the postpartum state (7,8). (cdc.gov)
  • Catheter-associated urinary tract infections are generally assumed to be benign. (cdc.gov)
  • The natural history of catheter associated urinary tract infections has been largely unstudied. (cdc.gov)
  • abstract = "The outcome of bacterial infection in plants is determined by the ability of the pathogen to successfully occupy the apoplastic space and deliver a constellation of effectors that collectively suppress basal and effector-triggered immune responses. (aber.ac.uk)
  • ABSTRACT Pseudomonas aeruginosa is an important agent of opportunistic infection in aquatic environments. (who.int)
  • Jason Pogue, PharmD, BCPS-ID, explains the limitations of the current drugs for the treatment of Pseudomonas aeruginosa infections. (contagionlive.com)
  • The limitation of the current drugs for the treatment of Pseudomonas [ aeruginosa ] is simple. (contagionlive.com)
  • Overall, the IL-17A cytokine represents a potential host-based intervention to ameliorate lung physiology without compromising host resistance against pathogens during chronic airway infection. (unicam.it)
  • As antibiotic resistance in microbial pathogens embodies a global threat to public health, it demands the development of novel strategies for managing microbial infections. (nature.com)
  • Over the last decade, research on antimicrobials has shifted towards an alternative approach to combat pathogens using anti-infective drugs that selectively interrupt virulence pathways to help prevent or cure bacterial infections. (nature.com)
  • What are the Limitations of Current Drugs to Treat Pseudomonas Infections? (contagionlive.com)
  • Bacteria like P. aeruginosa are able to colonize this mucus and cause chronic infections, which cannot be eradicated by antibiotic treatment [ 4 ]. (biomedcentral.com)
  • Pseudomonas bacteria, including Pseudomonas aeruginosa , are present throughout the world in soil and water. (msdmanuals.com)
  • Ear Canal Infection (Swimmer's Ear) Bacteria and sometimes fungi can cause acute infection of the skin of the ear canal. (msdmanuals.com)
  • Ear canal infection is caused by bacteria or, less commonly, fungi. (msdmanuals.com)
  • Pseudomonas bacteria live in soil, water and plants. (herbpathy.com)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefizox and other antibacterial drugs, Cefizox should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
  • Pseudomonas is a type of bacteria found commonly in the environment in soil and in water. (prgazette.com)
  • It is a serious health issue worldwide with a mortality rate ranging from 18% to 61%, Pseudomonas Aeruginosa Infection is treated by a combination of medicines and antibiotics.Pseudomonas aeruginosa is commonly found in the environment and can spread to people in healthcare settings when they are exposed to water or soil that is contaminated with these bacteria. (prgazette.com)
  • What Is Pseudomonas Aeruginosa Bacteria? (personalinjurylawcal.com)
  • Pseudomonas aeruginosa is a type of bacteria. (personalinjurylawcal.com)
  • It was the beginning of a national outbreak caused by an extremely worrisome bacteria - one that some say heralds an era in which antibiotics no longer work and seemingly routine infections get horribly out of hand. (woodtv.com)
  • The hospital that reported the first infection determined it was caused by a bacteria called Pseudomonas aeruginosa. (woodtv.com)
  • Drug-resistant strains of the bacteria cause more than 30,000 infections annually among hospitalized patients in the U.S. and more than 2,500 deaths, the CDC said. (woodtv.com)
  • But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. (eurekalert.org)
  • A person with a chronic infection might be fine one day, but environmental changes in the body can cause bacteria to change their behavior. (eurekalert.org)
  • This is a common environmental characteristic of bacterial infections, as bacteria frequently encounter oxygen deprivation during chronic infections. (eurekalert.org)
  • They observed that when SicX wasn't present, the bacteria easily disseminated from chronic infections throughout the body, causing systemic infection. (eurekalert.org)
  • The most common type of bacteria that causes perichondritis infection is Pseudomonas aeruginosa . (medlineplus.gov)
  • Bacteria have evolved multiple strategies for causing infections that include producing virulence factors, undertaking motility, developing biofilms and invading host cells. (nature.com)
  • Healthcare providers treating VIM-GES-CRPA infections should consult with a specialist knowledgeable in the treatment of antibiotic-resistant bacteria to determine the best treatment option. (cdc.gov)
  • Empirical combination therapy is recommended for patients with known or suspected Pseudomonas aeruginosa (PA) infections as a means to decrease the likelihood of administering inadequate antimicrobial treatment, to prevent the emergence of resistance, and to achieve a possible additive or even synergistic effect. (wustl.edu)
  • MBLs have been reported worldwide among Pseudomonas aeruginosa isolates ( 2 ). (blogspot.com)
  • During 2009-2016, infections with IMP-19-producing P. aeruginosa isolates were detected in 7 patients in the Hematology Department of University Hospital François Mitterrand, a 1,600-bed hospital in Dijon, France. (blogspot.com)
  • Methods: Consecutive non-replicate P. aeruginosa clinical isolates (935) from bloodstream infections and lower respiratory tract infections were collected from 20 centres distributed across Italy from September 2013 to November 2014. (torvergata.it)
  • The infectivity phenotype of each temperate phage lysate was evaluated by performing a cross-infection screen against all bacterial isolates and tested for associations with clinical variables. (ncl.ac.uk)
  • Intravesical BCG prescribing information states that antimicrobial therapy for other infections may interfere with the effectiveness of BCG intravesical. (medscape.com)
  • Effect of adequate single-drug versus combination antimicrobial therapy on mortality in Pseudomonas aeruginosa bloodstream infections. (wustl.edu)
  • These results suggests that treatment with combination antimicrobial therapy did not reduce the mortality risk compared with single-drug therapy in PA bloodstream infections. (wustl.edu)
  • This study was designed to identify the diverse communities of mobile P. aeruginosa phages by employing novel metagenomic methods, to determine cross infectivity, and to demonstrate the influence of phage infection on antimicrobial susceptibility. (ncl.ac.uk)
  • Temperate phage infection altered the antimicrobial susceptibility of PAO1 at subinhibitory concentrations of antibiotics, suggesting they may be precursory to antimicrobial resistance. (ncl.ac.uk)
  • P. aeruginosa bacteremia is a common and severe infection carrying high mortality in older adults . (bvsalud.org)
  • Objectives: Pseudomonas aeruginosa is a major cause of severe healthcare-associated infections and often shows MDR phenotypes. (torvergata.it)
  • Lawsuits claim it has caused severe infections in those who used contaminated products. (personalinjurylawcal.com)
  • These infections can cause severe damage, including blindness. (medicalxpress.com)
  • Coronavirus Disease 2019 (COVID-19) is a fatal lung infection caused by the novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which has influenced millions of people globally since its onset. (frontiersin.org)
  • P. oryzihabitans can also be a human pathogen, although infections are rare. (wikipedia.org)
  • Pseudomonas aeruginosa is well known as an opportunistic human pathogen characterized by a high intrinsic antibiotic tolerance [ 1 , 2 ]. (biomedcentral.com)
  • The effect of high soil nitrogen on gene expression in tomato during infection by Pseudomonas syringae pv. (bspp.org.uk)
  • The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. (aber.ac.uk)
  • Dive into the research topics of 'The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. (aber.ac.uk)
  • However, clearance of an infection is not only dependent on the ability of the host to induce an immune response following pathogen recognition, but also on the strategies of the pathogen to evade immune defense mechanisms and to express pathogenicity factors allowing them to establish a niche in the host. (elifesciences.org)
  • CP-CRPA infections tilation during 3 of 5 weeks of hospitalization in an intensive are highly transmissible in health care settings because they care unit (ICU) room (room X). Carbapenemase-producing can spread from person to person and from environmental carbapenem-resistant Pseudomonas aeruginosa (CP-CRPA) was sources such as sink drains and toilets. (cdc.gov)
  • 2021-January 2022, an Idaho hospital (hospital A) isolated hospital-acquired infection. (cdc.gov)
  • Pseudomonas Aeruginosa Infection Treatment Market size was valued at USD 1.23 Billion in 2021 and is projected to reach USD 1.85 Billion by 2028, growing at a CAGR of 6% from 2022 to 2028. (prgazette.com)
  • The latest research on the Pseudomonas Aeruginosa Infection Treatment market provides a comprehensive overview of the market for the years 2022 to 2028. (prgazette.com)
  • Since eradication of chronic P. aeruginosa infections by antibiotics fails, phage therapy is a possibility to treat bacterial infections. (biomedcentral.com)
  • Treatment of such infections can be difficult due to multiple antibiotic resistance, and in the United States, there was an increase in MDRPA (Multidrug-resistant Pseudomonas aeruginosa) resistant to ceftazidime, ciprofloxacin, and aminoglycosides, from 0.9% in 1994 to 5.6% in 2002. (wikipedia.org)
  • On September 17, 2021, an Idaho hospital (hospital A) Treatment of carbapenemase-producing carbapenem-resis- collected sputum by endotracheal tube aspiration of a woman tant Pseudomonas aeruginosa (CP-CRPA) infections is chal- aged 50-65 years (patient 1), who received mechanical ven- lenging because of antibiotic resistance. (cdc.gov)
  • We used an artificial sputum medium to study phage infection under conditions similar to a chronic lung infection. (biomedcentral.com)
  • Phage infection experiments under simulated chronic lung infection conditions showed that alginate production reduces phage infection efficiency. (biomedcentral.com)
  • aeruginosa lung infection on which bacteriophage could be assessed for their efficacy as a therapeutic agent. (brighton.ac.uk)
  • Lung infection with P. aeruginosa is often associated with production of various inflammatory cytokines including IL-1β. (cellmolbiol.org)
  • Similarly, no significant differences in bacterial clearance, neutrophil infiltration and NF-κB activation were observed between wild-type and AIM2-deficient mice following P. aeruginosa lung infection. (cellmolbiol.org)
  • While the temperate phages of the Liverpool epidemic strain have been shown to be active in the human lung and enhance fitness in a rat lung infection model, little is known about their mobilization more broadly across P. aeruginosa in chronic respiratory infection. (ncl.ac.uk)
  • The 3 stages of Pseudomonas infections are (1) bacterial attachment and colonization, (2) local infection, and (3) bloodstream dissemination and systemic disease. (medscape.com)
  • Pseudomonal infection, as described by Pollack, occurs in 3 stages: (1) bacterial attachment and colonization, followed by (2) local invasion and (3) dissemination and systemic disease. (medscape.com)
  • The skin lesions are a localized septic vasculitis with subsequent skin infarction that is highly associated with systemic Pseudomonas aeruginosa infection. (aafp.org)
  • Patient outcomes include permanent vision loss resulting from cornea infection, hospitalization, and one death due to systemic infection. (cdc.gov)
  • 2014. 2,3-Dihydroxybenzoic acid-containing nanofiber wound dressings inhibits biofilm formation by Pseudomonas aeruginosa . (sasm.org.za)
  • Pseudomonas aeruginosa is a biofilm-forming opportunistic pathogen which causes chronic infections in immunocompromised patients and leads to high mortality rate. (frontiersin.org)
  • In 1882, Gessard first discovered Pseudomonas , a strictly aerobic, gram-negative bacterium of relatively low virulence. (medscape.com)
  • CF is a multi-organ disease, however the cause of death is most often due to respiratory failure caused by infection of the airway epithelia with the bacterium Pseudomonas aeruginosa. (brighton.ac.uk)
  • N -acylhomoserine lactone (AHL)-mediated quorum sensing (QS) tightly regulates the expression of multiple virulence factors in the opportunistic pathogenic bacterium Pseudomonas aeruginosa . (nature.com)
  • Availability of iron increases host susceptibility to K pneumoniae infection. (medscape.com)
  • The risk of acquiring a urinary tract infection depends on the method and duration of catheterization, the quality of catheter care, and host susceptibility. (cdc.gov)
  • Antibiotics are applied externally for external infections or given intravenously for more serious, internal infections. (msdmanuals.com)
  • Pseudomonas strains were never resistant to wide spectrum antibiotics. (who.int)
  • Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas. (wikipedia.org)
  • The current classification of the genus Pseudomonas is divided into 5 groups based on ribosomal RNA (rRNA)/DNA homology. (medscape.com)
  • K pneumoniae and K oxytoca are the 2 members of this genus responsible for most human infections. (medscape.com)
  • Respiratory tract infection with Pseudomonas aeruginosa is a major cause of hospital-acquired pneumonia in immune-compromised individuals. (cellmolbiol.org)
  • Contagious ecthyma (also known as orf) is a zoonotic, mucocutaneous infection caused by a parapoxvirus (i.e., orf virus). (aafp.org)
  • Pseudomonas aeruginosa colonization reportedly occurs in more than 50% of humans, and P aeruginosa is the most common pseudomonal species. (medscape.com)
  • Review of common exposures revealed that most patients, including most patients with eye infections, used artificial tears prior to identification of VIM-GES-CRPA infection or colonization. (cdc.gov)
  • Relationship between ceftolozane-tazobactam exposure and selection for Pseudomonas aeruginosa resistance in a hollow-fiber infection model. (jmilabs.com)
  • Conclusions: Ceftolozane/tazobactam exhibited potent in vitro activity against P. aeruginosa causing invasive infections in Italy. (torvergata.it)
  • Outcomes of octogenarians and nonagenarians with Pseudomonas aeruginosa bacteremia: a multicenter retrospective study. (bvsalud.org)
  • Recent reports prompt the hypothesis that chronic lung disease associated to persistent infections, such as Pseudomonas aeruginosa, may be mediated by IL-17 immunity. (unicam.it)
  • The effects of exotoxin A (EXA) from Pseudomonas aeruginosa on polymorphonuclear leucocytes (PMNLs) were studied in a mouse model and in vitro. (nih.gov)
  • However, little is known about the factors which influence phage infection of P. aeruginosa under infection conditions and suitable broad host range phages. (biomedcentral.com)
  • Human Immunodeficiency Virus (HIV) Infection Human immunodeficiency virus (HIV) infection is a viral infection that progressively destroys certain white blood cells and is treated with antiretroviral medications. (msdmanuals.com)
  • The CDC said the virus is particularly susceptible to bacterial and viral infections, including the common coronavirus Pseudomonas aeruginosa. (opinionators.com)
  • Upon SARS-CoV-2 infection, viral RNA is released in target cells and immediately translated to produce viral polyprotein including the 3CL protease (NSP5). (invivogen.com)
  • Due to their hemolytic activity, even non-pathogenic species of Pseudomonas can occasionally become a problem in clinical settings, where they have been known to infect blood transfusions. (wikipedia.org)
  • In conclusion, the current authors confirmed an agreement between Pseudomonas aeruginosa status according to the new definition and clinical status, as well as with the level of Pseudomonas aeruginosa antibodies. (ersjournals.com)
  • Health Laboratory (UPHL), and CDC was undertaken to No patients were placed in room X after the second clinical identify the etiology of the infection. (cdc.gov)
  • Although the diagnosis is often clinical, because this infection is similar in appearance to cutaneous anthrax, definitive diagnosis may be needed. (aafp.org)
  • The study provides answers to the long-standing questions about how and why chronic infections become acute. (eurekalert.org)
  • Pseudomonas aeruginosa AIM2 inflammasome respiratory infection macrophage. (cellmolbiol.org)
  • We examined this in the context of Pseudomonas aeruginosa macrophage infection, which triggers NLRC4 inflammasome activation. (ox.ac.uk)
  • Fennel honey, propolis and bee venom significantly improve the immune response of rats to staphylococcal infection. (greenmedinfo.com)
  • Similar symptoms although also very rare can be seen by infections of P. luteola. (wikipedia.org)
  • What Are The Symptoms Of A Pseudomonas Aeruginosa Eye Infection? (personalinjurylawcal.com)
  • Advise patients who used EzriCare Artificial Tears to monitor for signs and symptoms of infection. (cdc.gov)
  • A monoclonal antibody (MAb) against EXA prevented the death of the mice if it was given simultaneously with, or 2 h before, infection with strain PA103. (nih.gov)
  • In this study, we found that P. aeruginosa infection induced degradation of AIM2 protein in macrophages and induction of AIM2 mRNA expression in macrophages and in the lung of mice. (cellmolbiol.org)
  • Interestingly, P. aeruginosa infection induced a similar level of IL-1β, IL-6 and TNF production in wild-type and AIM2-deficient mice. (cellmolbiol.org)
  • Investigators showed higher rates of infection in experimental mice deficient in the genes that control expression of these 2 agents. (medscape.com)
  • Subsequently, the organism has been found in numerous catheter-associated UTIs, wound infections, and IV catheter-associated bacteremias. (medscape.com)
  • Adoption of the closed method of urinary drainage has markedly reduced the risk of acquiring a catheter-associated infection, but the risk is still substantial. (cdc.gov)
  • Bacterial infection can trigger autophagy and inflammasome activation, but the effects of inflammasome activation on autophagy are unknown. (ox.ac.uk)
  • This can lead to acute infection, and a person could develop sepsis that requires immediate treatment. (eurekalert.org)
  • The Bacterial Infection that attacks a person who is either ill or having a Weak Immune System is called Pseudomonas Infection. (herbpathy.com)
  • This undermines the effectiveness of the available treatment options and thus contributes to the persistence of microbial infections. (who.int)
  • We performed a post-hoc analysis of patients with PA bloodstream infections from a published prospective cohort. (wustl.edu)
  • Conclusions Once-daily Arikace demonstrated acute tolerability, safety, biologic activity and efficacy in patients with CF with P aeruginosa infection. (bmj.com)
  • Since most CF centres do not see the patients monthly and do not have access to regular Pa antibody measurement, the European consensus definition for chronic Pa infection is more commonly used, i.e. at least three positive cultures over ≥6 months with at least a 1-month interval between the samples 4 . (ersjournals.com)
  • Intermittent infection refers to patients with ≤50% of Pa positive cultures. (ersjournals.com)
  • The infections were found in different parts of the body - in the blood of some patients, in the lungs of others. (woodtv.com)
  • The problematic opportunistic pathogen Pseudomonas aeruginosa is a major cause of infection in patients with underlying or immunocompromising conditions. (elifesciences.org)
  • Reported infection rates vary widely, ranging from 1%-5%, after a single brief catheterization (3) to virtually 100% for patients with indwelling urethral catheters draining into an open system for longer than 4 days (4). (cdc.gov)
  • In these studies, errors in maintaining sterile closed drainage were common and predisposed patients to infection. (cdc.gov)
  • Such infection in otherwise healthy patients is often asymptomatic and is likely to resolve spontaneously with the removal of the catheter. (cdc.gov)
  • these bottles were collected from patients with and without eye infections in two states. (cdc.gov)