A plant genus of the family FABACEAE that is a source of psoralen (FICUSIN).
An oil-resistant synthetic rubber made by the polymerization of chloroprene.
A type of COUMARINS with added pyran ring(s).
An occupational discipline founded by D.D. Palmer in the 1890's based on the relationship of the spine to health and disease.
Procedures used by chiropractors to treat neuromusculoskeletal complaints.
Cooperation among hospitals for the purpose of sharing various departmental services, e.g., pharmacy, laundry, data processing, etc.
Adjustment and manipulation of the vertebral column.
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.

The presence of three isoflavonoid compounds in Psoralea corylifolia. (1/12)

The optimization of a high-performance liquid chromatographic method to determine three isoflavonoids (daidzein, genistein, and biochanin A) in the fruit of Psoralea corylifolia is developed and validated. Dried psoralea fruit powder is extracted with aqueous methanol followed by the hydrolysis of the analytes' conjugated glycosides with hydrochloric acid. The HPLC assay is performed on a reverse-phase C18 column with gradient elution using acetonitrile and 10% acetic acid as the mobile phase at a flow rate of 0.8 mL/min. Flavone is used as the internal standard and the substances are detected at 260 nm. Calibrations are linear (correlation coefficient > or = 0.995) for all three analytes. The limits of detection are 0.01 microg/mL for daidzein and genistein and 0.1 microg/mL for biochanin A. The overall intra- and interassay precision range from 2.5% to 4.9% and from 0.5% to 4.7%, respectively. The method proved to be sensitive, specific, accurate, and precise for the determination of daidzein, genistein, and biochanin A in Psoralea corylifolia.  (+info)

Gonadal toxicity of an ethanol extract of Psoralea corylifolia in a rat 90-day repeated dose study. (2/12)

Ethanol extracts of seeds of Psoralea corylifolia are proposed as food additives for processed food preservation. An extract was administered by admixing into diet at concentrations of 0, 0.375, 0.75, 1.5 or 3.0% to 10 male and 10 female F344 rats each for 90 days to evaluate its toxicity. Body weight gain, food consumption and food conversion efficiency (body weight gain per food consumption) were lower in the extract-treated animals, except for the 0.375% males, as compared to the control animals. Absolute and/or relative testes weights in the 1.5 and 3.0% groups and those of ovaries in the 3.0% group were significantly (p < 0.01) lower than in the control group. On histopathological examination, seminiferous tubular atrophy and Leydig cell atrophy in the testes, and epithelial cell atrophy in the seminal vesicles and prostate were observed in the 1.5 and 3.0% males. Decrease in the number of corpora lutea associated with frequent necrotic follicles in the ovaries in the 1.5 and 3.0% females and less frequent endometrial glands in the uterus in the 3.0% females were also detected. These results might suggest disruption of the hypothalamus-pituitary-gonadal axis in Psoralea corylifolia-treated rats as possible mechanisms underlying this gonadal toxicity.  (+info)

Analysis of Psoralea corylifolia L. fruits in different regions. (3/12)

Application of multivariate data analysis has become a popular method in the last decades, mainly because it can provide information not otherwise accessible. The information includes classification, searching similarities, finding relationships, finding physical significance to principal components, etc. Twenty-two Chinese medicinal herbs containing twelve constituents were collected and determined by HPLC. The results were studied by hierarchical cluster analysis (HCA) and principal components analysis (PCA). It was shown that the samples could be clustered reasonably into three groups, hence corresponding with the typical habitats of Psoralea corylifolia L.  (+info)

Prenylflavones from Psoralea corylifolia inhibit nitric oxide synthase expression through the inhibition of I-kappaB-alpha degradation in activated microglial cells. (4/12)

The overproduction of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) switches the function of NO from a physiological neuromodulator to a neurotoxic effector in central nervous system (CNS) after brain injury. From the methanol extracts of Psoralea corylifolia, we purified two inhibitors of NO production in lipopolysaccharide (LPS)-activated microglia by activity guided purification along with two inactive compounds. The active compounds were identified as a chromenoflavanone [7,8-dihydro-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo-(1,2-b:5,4-b')dipyran-6 -one] (1) and 4-hydroxylonchocarpin (2). And the inactive two compounds were identified as bavachinin (3) and bavachalcone (4) by spectral analysis. The compound 2 was isolated first time from this plant. Compounds 1 and 2 inhibited the production of NO in LPS-activated microglia in a dose dependent manner (IC(50)'s were 11.4, 10.2 microM, respectively). They also suppressed the expression of protein and mRNA of iNOS in LPS-activated microglial cells at 10 muM as observed in Western blot analysis and RT-PCR experiment. Furthermore they inhibited the degradation of I-kappaB-alpha in activated microglia. These results imply that compounds 1 and 2 can be lead compounds for the development of neuroprotective drug with the inhibitory activity of NO overproduction by activated microglial cells.  (+info)

Psoralenoside and isopsoralenoside, two new benzofuran glycosides from Psoralea corylifolia. (5/12)

Two new benzofuran glycosides, called psoralenoside and isopsoralenoside, were isolated from the fruits of Psoralea corylifolia, together with nine known compounds. Their structures were elucidated by detailed spectral analyses including extensive two dimensional (2D) NMR spectra.  (+info)

Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia. (6/12)

The ethyl acetate-soluble fraction of the methanolic extract from the seeds of Psoralea corylifolia was found to inhibit the release of beta-hexosaminidase, as a marker of antigen-IgE-induced degranulation in RBL-2H3 cells. Sixteen constituents were isolated from the ethyl acetate-soluble fraction and several constituents, Delta(1),3-hydroxybakuchiol (IC(50) = 49 microM), Delta(3),2-hydroxybakuchiol (69 microM, bavachin (58 microM), and psoralidin (ca. 100 microM), showed inhibitory activities against the antigen-induced degranulation.  (+info)

Antidepressant-like effects of psoralen isolated from the seeds of Psoralea corylifolia in the mouse forced swimming test. (7/12)

The forced swimming test (FST) is suggested to produce abnormalities in the serotonergic and hypothalamic-pituitary-adrenal (HPA) axis systems. Therefore, compounds that attenuate these neurobiological alterations may have potential as antidepressants. The behavioral and biochemical effects of psoralen, a major furocoumarin isolated from Psoralea corylifolia, were investigated in the FST model of depression in male mice. Psoralen significantly reduced immobility and increased swimming without altering climbing in the mouse FST. Psoralen remarkably reversed FST-induced alterations in serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) levels in frontal cortex and hippocampus in mice. Furthermore, psoralen attenuated FST-induced elevations in serum corticotropin-releasing factor (CRF) and corticosterone concentrations to normalize the HPA axis activity. These results suggested that psoralen possessed potent antidepressant-like properties which were at least in part mediated by improving the abnormalities in the serotonergic and the HPA axis systems.  (+info)

Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia. (8/12)

Numerous compounds detected in medical plants and dietary components or supplements possess chemopreventive, antitumor and immunomodulatory properties. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an important endogenous anticancer factor that induces apoptosis selectively in cancer cells. However, some tumor cells are resistant to TRAIL-mediated apoptosis. Naturally occurring agents could sensitize TRAIL-resistant cancer cells and augment their apoptotic activity.We examined the cytotoxic and apoptotic effects of neobavaisoflavone and psoralidin in combination with TRAIL on LNCaP prostate cancer cells. The cytotoxicity was evaluated by MTT and LDH assays. The apoptosis was detected using Annexin V-FITC by flow cytometry and fluorescence microscopy. The LNCaP cells were shown to be resistant to TRAIL-induced apoptosis. Our study demonstrated that neobavaisoflavone and psoralidin sensitized TRAIL-resistant cells and markedly augmented TRAIL-mediated apoptosis and cytotoxicity in prostate cancer cells. Cotreatment of LNCaP cells with 100 ng/ml TRAIL and 50 muM neobavaisoflavone or 50 muM psoralidin increased the percentage of the apoptotic cells to 77.5+/-0.5% or 64.4+/-0.5%, respectively. The data indicate the potential role of the bioactive compounds isolated from the medicinal plant Psoralea corylifolia (neobavaisoflavone and psoralidin) in prostate cancer chemoprevention through enhancement of TRAIL-mediated apoptosis.  (+info)

Psoralea is a genus of plants in the legume family, Fabaceae. However, in a medical context, Psoralea seeds or fruits are sometimes referred to as a traditional herbal remedy in certain cultures. The seeds contain compounds with potential medicinal properties, such as psoralen, which can increase skin sensitivity to sunlight and have been used in the treatment of vitiligo, a condition that causes depigmentation of the skin.

It's important to note that the use of Psoralea seeds as a medical treatment is not widely accepted or studied in modern medicine, and they can have side effects, including nausea, vomiting, and increased risk of skin cancer with excessive sun exposure. Therefore, it should only be used under the guidance of a healthcare professional.

Neoprene is not a medical term, but it is a material that is used in some medical applications. Neoprene is a type of synthetic rubber that is known for its flexibility, durability, and resistance to heat, water, and chemicals. It is often used in the manufacture of medical devices such as braces, supports, and protective gear.

In medical terms, neoprene may be referred to as a component of a device or material used in medical applications. For example, a neoprene sleeve may be used as a compression garment for venous insufficiency or lymphedema management. Neoprene is also sometimes used in the manufacture of medical gloves and other protective equipment due to its resistance to chemicals and other substances.

However, it's important to note that some people may have allergic reactions to neoprene, causing skin irritation or other symptoms. Therefore, healthcare providers should consider patients' individual needs and potential allergies when selecting medical devices made of neoprene or other materials.

Pyranocoumarins are a type of chemical compound that are found in various plants. They are characterized by a furanocoumarin structure, which is a combination of a furan ring (a five-membered aromatic ring containing four carbon atoms and one oxygen atom) and a coumarin ring (a six-membered aromatic ring containing two carbonyl groups).

Pyranocoumarins are known to have various biological activities, including phototoxic, antimicrobial, and anti-inflammatory effects. They can also inhibit certain enzymes, such as cytochrome P450 enzymes, which are involved in drug metabolism. Some pyranocoumarins have been studied for their potential use in cancer therapy, although more research is needed to fully understand their mechanisms of action and safety profiles.

Chiropractic is a health care profession that focuses on the diagnosis, treatment, and prevention of disorders of the neuromusculoskeletal system, with an emphasis on the spine. Chiropractors use manual therapies, including spinal manipulation and adjustment, to realign the spine and improve function, reduce pain, and promote overall health and well-being.

The primary goal of chiropractic care is to correct subluxations, or misalignments of the vertebrae in the spine, which can cause nerve interference and affect the body's natural ability to heal itself. Chiropractors may also use other therapies such as exercise, nutrition counseling, and lifestyle modifications to help patients achieve optimal health and wellness.

Chiropractic is a drug-free and non-surgical approach to healthcare that is recognized by major regulatory bodies around the world. It has been shown to be effective for a wide range of conditions, including back pain, neck pain, headaches, and other musculoskeletal disorders.

Chiropractic manipulation, also known as spinal manipulative therapy, is a technique used by chiropractors to realign misaligned vertebrae in the spine (subluxations) with the goal of improving function, reducing nerve irritation, and alleviating pain. This technique involves using controlled force, direction, amplitude, and velocity to move joints beyond their passive range of motion but within their physiological limits. The purpose is to restore normal joint motion and function, which can help reduce pain and improve overall health and well-being. It is commonly used to treat musculoskeletal conditions such as low back pain, neck pain, and headaches.

I couldn't find a medical definition for "Hospital Shared Services" as it is more related to hospital administration and management. Here's a definition from a healthcare management perspective:

Hospital Shared Services refer to centralized support services that are shared between different departments or hospitals within a healthcare system. These services can include areas such as:

1. Clinical engineering: Management of medical equipment, maintenance, and repair services.
2. Laboratory services: Centralized laboratory testing and analysis.
3. Radiology and imaging services: Consolidation of radiology and imaging services for improved efficiency and quality.
4. Sterile processing services: Centralization of sterilization and decontamination of medical instruments and supplies.
5. Food and nutrition services: Shared kitchen, meal planning, and delivery services.
6. Environmental services: Shared housekeeping, laundry, and waste management services.
7. Biomedical waste management: Handling, treatment, and disposal of hazardous medical waste.
8. Information technology (IT) services: Centralized IT infrastructure, support, and data management.
9. Human resources: Shared HR functions such as recruitment, training, and benefits administration.
10. Financial services: Shared accounting, billing, and revenue cycle management.

The goal of Hospital Shared Services is to improve operational efficiency, reduce costs, enhance quality, and standardize processes across the healthcare system.

Spinal manipulation is a manual therapy technique often used in the practice of chiropractic, osteopathic medicine, and physical therapy. It involves applying controlled force to the spinal joints, usually through quick and precise thrusting movements. The goal of this technique is to improve mobility and range of motion in the spine, reduce pain and muscle tension, and promote overall function of the nervous system. Spinal manipulation may also be used to treat various conditions such as low back pain, neck pain, headaches, and other musculoskeletal disorders. It is important to note that spinal manipulation should only be performed by licensed healthcare professionals with proper training and expertise in this technique.

Medical Definition of Vitamin A:

Vitamin A is a fat-soluble vitamin that is essential for normal vision, immune function, and cell growth. It is also an antioxidant that helps protect the body's cells from damage caused by free radicals. Vitamin A can be found in two main forms: preformed vitamin A, which is found in animal products such as dairy, fish, and meat, particularly liver; and provitamin A carotenoids, which are found in plant-based foods such as fruits, vegetables, and vegetable oils.

The most active form of vitamin A is retinoic acid, which plays a critical role in the development and maintenance of the heart, lungs, kidneys, and other organs. Vitamin A deficiency can lead to night blindness, dry skin, and increased susceptibility to infections. Chronic vitamin A toxicity can cause nausea, dizziness, headaches, coma, and even death.

Research, in the context of medicine, is a systematic and rigorous process of collecting, analyzing, and interpreting information in order to increase our understanding, develop new knowledge, or evaluate current practices and interventions. It can involve various methodologies such as observational studies, experiments, surveys, or literature reviews. The goal of medical research is to advance health care by identifying new treatments, improving diagnostic techniques, and developing prevention strategies. Medical research is typically conducted by teams of researchers including clinicians, scientists, and other healthcare professionals. It is subject to ethical guidelines and regulations to ensure that it is conducted responsibly and with the best interests of patients in mind.

Vitamin D is a fat-soluble secosteroid that is crucial for the regulation of calcium and phosphate levels in the body, which are essential for maintaining healthy bones and teeth. It can be synthesized by the human body when skin is exposed to ultraviolet-B (UVB) rays from sunlight, or it can be obtained through dietary sources such as fatty fish, fortified dairy products, and supplements. There are two major forms of vitamin D: vitamin D2 (ergocalciferol), which is found in some plants and fungi, and vitamin D3 (cholecalciferol), which is produced in the skin or obtained from animal-derived foods. Both forms need to undergo two hydroxylations in the body to become biologically active as calcitriol (1,25-dihydroxyvitamin D3), the hormonally active form of vitamin D. This activated form exerts its effects by binding to the vitamin D receptor (VDR) found in various tissues, including the small intestine, bone, kidney, and immune cells, thereby influencing numerous physiological processes such as calcium homeostasis, bone metabolism, cell growth, and immune function.

Psoralea glaucina Harv. Psoralea gueinzii Harv. Psoralea hamata Harv. Psoralea heterosepala Fourc. Psoralea hirta L. Psoralea ... Psoralea semota C.H.Stirt. Psoralea sericea Poir. Psoralea sordida C.H.Stirt. & Muasya Psoralea speciosa Eckl. & Zeyh. Psoralea ... Psoralea aphylla L. Psoralea arborea Sims Psoralea arborescens (C.H.Stirt.) C.H.Stirt. Psoralea argentea Thunb. Psoralea ... Psoralea pinnata L. Psoralea platyphylla C.H.Stirt. Psoralea plauta C.H.Stirt. Psoralea polyphylla Eckl. & Zeyh. Psoralea ...
Psoralea argophylla is a PERENNIAL growing to 0.6 m (2ft). The species is hermaphrodite (has both male and female organs) and ... Psoralea mephitica. Perennial. 0.0. - LMH. N. DM. 2. 0. 2. Psoralea orbicularis. Roundleaf Leather Root. Perennial. 0.1. 5-9 ... Psoralea canescens. Buckroot. Perennial. 0.0. - LM. N. DM. 2. 1. 2. Psoralea castorea. Beaver Indian breadroot. Perennial. 0.5 ... Psoralea pedunculata. Sampsons Snakeroot. Perennial. 1.0. - LMH. N. DM. 0. 1. Psoralea subacaulis. Whiterim scurfpea. ...
Key words: Psoralea cinerea / Psoralea plumosa / Bradyrhizobium / germination / vegetative growth / yield / furocoumarin Mots ... Psoralea cinerea and Psoralea plumosa. The germination method was shown to be very efficient (germination rate about 90%). The ... Psoralea cinerea et Psoralea plumosa. Les semences présentent une double inhibition de germination. La première est dordre ... Study of two pharmaceutically useful Psoralea (Leguminosae) species : influence of inoculation on growth, grain and dry matter ...
Gk. psoraleos = scabby. The plants are covered with rough warty-looking glandular dots ...
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Bakučiolis yra meroterpeno fenolis*, kurio gausu augalų Psoralea corylifolia (Linn) sėklose (babchi) ir lapuose.*Meroterpenas ... Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review https://onlinelibrary.wiley.com/doi/full/ ...
Psoralea Corylifolia seeds Oil. Psoralea corylifolia (Babchi) is a plant utilized in Indian and Chinese conventional medication ...
Symptoms for Psoralea Corylifolia It has a powerful action on the skin, as it causes dilatation of arterioles. It is useful in ... Psoralea Corylifolia(Mother Tincture) Common Name: Babachi Causes & ... Psoralea Corylifolia(Mother Tincture). Common Name: Babachi. Causes & Symptoms for Psoralea Corylifolia. *It has a powerful ... Complaints of ulcer, are relieved with Psoralea Corylifolia.. Side effects of Psoralea Corylifolia. There are no such side ...
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Bu Gu Zhi - Psoralea fruit - "Tonify Bone Resin". May22. by Peter Borten ...
PSORALEA CORYLIFOLIA OIL & BASIL OIL Manufacturer from Delhi, India ...
Psoralea corylifolia L. found in tropical and subtropical region of the world is one of the medicinal herbs used in Unani ... Abstract: Psoralea corylifolia L. found in tropical and subtropical region of the world is one of the medicinal herbs used in ... Psoralea corylifolia Babchi: A popular herb of Unani, Ayurvedic and Chinese system of medicine for Vitiligo. Int J Herb Med ... Psoralea corylifolia Babchi: A popular herb of Unani, Ayurvedic and Chinese system of medicine for Vitiligo. ...
Psoralea jamesii Torrey. Dalea jamesii has bright yellow flowers in clusters that turn reddish brown as they age. The leaves ...
Psoralea corylifolia) is commonly known as Purple Flames, which has many medicinal properties. Bakuchi is well known for its ... Bakuchi (Psoralea corylifolia) is commonly known as Purple Flames, which has many medicinal properties. Bakuchi is helpful in ... Phytoconstituents Of Bakuchi- Psoralea Corylifolia. Bakuchi has a vast variety of plant-based Antioxidants which are anti- ... Practical Uses Of Bakuchi (Psoralea Corylifolia). *This has various medicinal properties and is known in the family Kusthghan ...
Phytophotodermatitis (PPD) is a cutaneous phototoxic inflammatory eruption resulting from contact with light-sensitizing botanical substances and long-wave ultraviolet (UV-A 320-380 nm) radiation. The eruption usually begins approximately 24 hours after exposure and peaks at 48-72 hours.
Psoralea corylifolia. Bu Gu Zhi. 1. 4. Ribes americanum. American Blackcurrant. 2. 1. ...
Psoralea tenuiflora. 7. 24. Medicago sativa. 2. 14. 41. Malvaceae. Sphaeralcea coccinea. 5. 4. 11. ...
Critical note on pretreatment (Shodhana) of Bakuchi (Psoralea corylifolia L.). Sarika Makwana, Nikhil Mehere, Prashant Bedarkar ... Bakuchi (Psoralea corylifolia L.) is an herb mainly indicated for the treatment of skin diseases in the classical text of ...
Psoralea physodes Douglas. Copyright © 2017 Regents of the University of California - Updated 02 June 2017. ...
Indigofera mexicana L.f. is a synonym of Psoralea mexicana (L.f.) Vail This name is a synonym of Psoralea mexicana (L.f.) Vail. ...
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Psoralea floribunda Nutt. ex Torr. & A. Gray, morePsoralea obtusifolia Torr. & A. Gray, Psoralea tenuiflora Pursh, Psoralea ... bigelovii (Rydb.) J.F. Macbr., Psoralea tenuiflora var. floribunda (Nutt. ex Torr. & A. Gray) Rydb., Psoralea tenuiflora var. ... Psoralea t.; Psoralea floribunda). Gleason, Henry A. & Cronquist, Arthur J. 1991. Manual of vascular plants of northeastern ... Etymology: Psoralidium is a diminutive of Psoralea, while tenuiflorum means with fine or delicate flowers. Synonyms: Psoralea ...
Psoralea onobrychis Dennis Kramb*Psoralea onobrychis AW*Psoralea onobrychis Dennis Kramb*psoralea Johannes-Ulrich Urban*tall ...
Psoralea (bu gu zhi). Pueraria (ge gen). Pulsatilla (bai tou weng). Pumice (fu hai shi). Pumpkin Seed (nan gua zi). Purslane ( ...
Psoralea (bu gu zhi). Pueraria (ge gen). Pulsatilla (bai tou weng). Pumice (fu hai shi). Pumpkin Seed (nan gua zi). Purslane ( ...
They have been observed on species of Cullen (=Psoralea): Cullen australasicum (tall verbine), C. badocanum, C. balsamicum, C. ...
Psoralea (bu gu zhi). Pueraria (ge gen). Pulsatilla (bai tou weng). Pumice (fu hai shi). Pumpkin Seed (nan gua zi). Purslane ( ...

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