An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.
A reflex found in normal infants consisting of dorsiflexion of the HALLUX and abduction of the other TOES in response to cutaneous stimulation of the plantar surface of the FOOT. In adults, it is used as a diagnostic criterion, and if present is a NEUROLOGIC MANIFESTATION of dysfunction in the CENTRAL NERVOUS SYSTEM.
An abnormal response to a stimulus applied to the sensory components of the nervous system. This may take the form of increased, decreased, or absent reflexes.
A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.
Time period from 1801 through 1900 of the common era.
Eponyms in medicine are terms that are named after a person, typically the physician or scientist who first described the disease, condition, or procedure, such as Alzheimer's disease or Parkinson's disease.
Any one of five terminal digits of the vertebrate FOOT.
Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.
Reflex contraction of a muscle in response to stretching, which stimulates muscle proprioceptors.
Time period from 1901 through 2000 of the common era.
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
Intra-aural contraction of tensor tympani and stapedius in response to sound.
A reflex wherein impulses are conveyed from the cupulas of the SEMICIRCULAR CANALS and from the OTOLITHIC MEMBRANE of the SACCULE AND UTRICLE via the VESTIBULAR NUCLEI of the BRAIN STEM and the median longitudinal fasciculus to the OCULOMOTOR NERVE nuclei. It functions to maintain a stable retinal image during head rotation by generating appropriate compensatory EYE MOVEMENTS.
Constriction of the pupil in response to light stimulation of the retina. It refers also to any reflex involving the iris, with resultant alteration of the diameter of the pupil. (Cline et al., Dictionary of Visual Science, 4th ed)
Recording of the changes in electric potential of muscle by means of surface or needle electrodes.
A condition characterized by abnormal posturing of the limbs that is associated with injury to the brainstem. This may occur as a clinical manifestation or induced experimentally in animals. The extensor reflexes are exaggerated leading to rigid extension of the limbs accompanied by hyperreflexia and opisthotonus. This condition is usually caused by lesions which occur in the region of the brainstem that lies between the red nuclei and the vestibular nuclei. In contrast, decorticate rigidity is characterized by flexion of the elbows and wrists with extension of the legs and feet. The causative lesion for this condition is located above the red nuclei and usually consists of diffuse cerebral damage. (From Adams et al., Principles of Neurology, 6th ed, p358)
A monosynaptic reflex elicited by stimulating a nerve, particularly the tibial nerve, with an electric shock.
The instinctive tendency (or ability) to assume a normal position of the body in space when it has been displaced.
Change of heartbeat induced by pressure on the eyeball, manipulation of extraocular muscles, or pressure upon the tissue remaining in the orbital apex after enucleation.
Receptors in the vascular system, particularly the aorta and carotid sinus, which are sensitive to stretch of the vessel walls.
Brief closing of the eyelids by involuntary normal periodic closing, as a protective measure, or by voluntary action.
Contractions of the abdominal muscles upon stimulation of the skin (superficial abdominal reflex) or tapping neighboring bony structures (deep abdominal reflex). The superficial reflex may be weak or absent, for example, after a stroke, a sign of upper (suprasegmental) motor neuron lesions. (Stedman, 25th ed & Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p1073)
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Use of electric potential or currents to elicit biological responses.
Contraction of the muscle of the PHARYNX caused by stimulation of sensory receptors on the SOFT PALATE, by psychic stimuli, or systemically by drugs.
A subtype of epilepsy characterized by seizures that are consistently provoked by a certain specific stimulus. Auditory, visual, and somatosensory stimuli as well as the acts of writing, reading, eating, and decision making are examples of events or activities that may induce seizure activity in affected individuals. (From Neurol Clin 1994 Feb;12(1):57-8)
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.
Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.
Neurons which activate MUSCLE CELLS.
A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)
A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.
Act of eliciting a response from a person or organism through physical contact.
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Neurons which send impulses peripherally to activate muscles or secretory cells.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
The dilated portion of the common carotid artery at its bifurcation into external and internal carotids. It contains baroreceptors which, when stimulated, cause slowing of the heart, vasodilatation, and a fall in blood pressure.
The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
The medial terminal branch of the sciatic nerve. The tibial nerve fibers originate in lumbar and sacral spinal segments (L4 to S2). They supply motor and sensory innervation to parts of the calf and foot.
Discharge of URINE, liquid waste processed by the KIDNEY, from the body.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The interruption or removal of any part of the vagus (10th cranial) nerve. Vagotomy may be performed for research or for therapeutic purposes.
An oval, bony chamber of the inner ear, part of the bony labyrinth. It is continuous with bony COCHLEA anteriorly, and SEMICIRCULAR CANALS posteriorly. The vestibule contains two communicating sacs (utricle and saccule) of the balancing apparatus. The oval window on its lateral wall is occupied by the base of the STAPES of the MIDDLE EAR.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
Cells specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptor cells may monitor external stimuli, as in TASTE and OLFACTION, or internal stimuli, such as the concentrations of OXYGEN and CARBON DIOXIDE in the blood.
Branches of the VAGUS NERVE. The superior laryngeal nerves originate near the nodose ganglion and separate into external branches, which supply motor fibers to the cricothyroid muscles, and internal branches, which carry sensory fibers. The RECURRENT LARYNGEAL NERVE originates more caudally and carries efferents to all muscles of the larynx except the cricothyroid. The laryngeal nerves and their various branches also carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.
An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
Biguanides are a class of oral hypoglycemic agents, including metformin, which primarily reduce blood glucose levels by decreasing hepatic gluconeogenesis and increasing insulin sensitivity, but not by stimulating insulin secretion, and they are commonly used in the treatment of type 2 diabetes.
A branch of the tibial nerve which supplies sensory innervation to parts of the lower leg and foot.
Skeletal muscle structures that function as the MECHANORECEPTORS responsible for the stretch or myotactic reflex (REFLEX, STRETCH). They are composed of a bundle of encapsulated SKELETAL MUSCLE FIBERS, i.e., the intrafusal fibers (nuclear bag 1 fibers, nuclear bag 2 fibers, and nuclear chain fibers) innervated by SENSORY NEURONS.
A complex involuntary response to an unexpected strong stimulus usually auditory in nature.
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
The position or attitude of the body.
The resection or removal of the nerve to an organ or part. (Dorland, 28th ed)
The time from the onset of a stimulus until a response is observed.
The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.
A movement, caused by sequential muscle contraction, that pushes the contents of the intestines or other tubular organs in one direction.
Contractile tissue that produces movement in animals.
Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
The lateral of the two terminal branches of the sciatic nerve. The peroneal (or fibular) nerve provides motor and sensory innervation to parts of the leg and foot.
Any operation on the spinal cord. (Stedman, 26th ed)
Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)
A gelatinous membrane overlying the acoustic maculae of SACCULE AND UTRICLE. It contains minute crystalline particles (otoliths) of CALCIUM CARBONATE and protein on its outer surface. In response to head movement, the otoliths shift causing distortion of the vestibular hair cells which transduce nerve signals to the BRAIN for interpretation of equilibrium.
GRAY MATTER located in the dorsomedial part of the MEDULLA OBLONGATA associated with the solitary tract. The solitary nucleus receives inputs from most organ systems including the terminations of the facial, glossopharyngeal, and vagus nerves. It is a major coordinator of AUTONOMIC NERVOUS SYSTEM regulation of cardiovascular, respiratory, gustatory, gastrointestinal, and chemoreceptive aspects of HOMEOSTASIS. The solitary nucleus is also notable for the large number of NEUROTRANSMITTERS which are found therein.
The function of opposing or restraining the excitation of neurons or their target excitable cells.
The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.
Voluntary or involuntary motion of head that may be relative to or independent of body; includes animals and humans.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. Such impulses are conducted via efferent neurons (NEURONS, EFFERENT), such as MOTOR NEURONS, autonomic neurons, and hypophyseal neurons.
Motion of an object in which either one or more points on a line are fixed. It is also the motion of a particle about a fixed point. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Voluntary or reflex-controlled movements of the eye.
Involuntary rhythmical movements of the eyes in the normal person. These can be naturally occurring as in end-position (end-point, end-stage, or deviational) nystagmus or induced by the optokinetic drum (NYSTAGMUS, OPTOKINETIC), caloric test, or a rotating chair.
Sensory functions that transduce stimuli received by proprioceptive receptors in joints, tendons, muscles, and the INNER EAR into neural impulses to be transmitted to the CENTRAL NERVOUS SYSTEM. Proprioception provides sense of stationary positions and movements of one's body parts, and is important in maintaining KINESTHESIA and POSTURAL BALANCE.
The lower portion of the BRAIN STEM. It is inferior to the PONS and anterior to the CEREBELLUM. Medulla oblongata serves as a relay station between the brain and the spinal cord, and contains centers for regulating respiratory, vasomotor, cardiac, and reflex activities.
A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.
The act of taking solids and liquids into the GASTROINTESTINAL TRACT through the mouth and throat.
A continuing periodic change in displacement with respect to a fixed reference. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Stretch receptors found in the bronchi and bronchioles. Pulmonary stretch receptors are sensors for a reflex which stops inspiration. In humans, the reflex is protective and is probably not activated during normal respiration.
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
A masticatory muscle whose action is closing the jaws.
The vestibular part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The vestibular nerve fibers arise from neurons of Scarpa's ganglion and project peripherally to vestibular hair cells and centrally to the VESTIBULAR NUCLEI of the BRAIN STEM. These fibers mediate the sense of balance and head position.
A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.
The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (VESTIBULAR LABYRINTH). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the SEMICIRCULAR DUCTS.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
The disappearance of responsiveness to a repeated stimulation. It does not include drug habituation.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Each of the upper and lower folds of SKIN which cover the EYE when closed.
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.
A derivative of CHLORAL HYDRATE that was used as a sedative but has been replaced by safer and more effective drugs. Its most common use is as a general anesthetic in animal experiments.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
An alkaloid, originally from Atropa belladonna, but found in other plants, mainly SOLANACEAE. Hyoscyamine is the 3(S)-endo isomer of atropine.
The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.
A tubular organ of VOICE production. It is located in the anterior neck, superior to the TRACHEA and inferior to the tongue and HYOID BONE.
Muscles arising in the zygomatic arch that close the jaw. Their nerve supply is masseteric from the mandibular division of the trigeminal nerve. (From Stedman, 25th ed)
Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
Elements of limited time intervals, contributing to particular results or situations.
The inferior part of the lower extremity between the KNEE and the ANKLE.
Neural tracts connecting one part of the nervous system with another.
Expulsion of milk from the mammary alveolar lumen, which is surrounded by a layer of milk-secreting EPITHELIAL CELLS and a network of myoepithelial cells. Contraction of the myoepithelial cells is regulated by neuroendocrine signals.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
The HEART and the BLOOD VESSELS by which BLOOD is pumped and circulated through the body.
The aperture in the iris through which light passes.
Bony structure of the mouth that holds the teeth. It consists of the MANDIBLE and the MAXILLA.
The four cellular masses in the floor of the fourth ventricle giving rise to a widely dispersed special sensory system. Included is the superior, medial, inferior, and LATERAL VESTIBULAR NUCLEUS. (From Dorland, 27th ed)
Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
The functions of the skin in the human and animal body. It includes the pigmentation of the skin.
Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.
The region of the lower limb between the FOOT and the LEG.
Physiological processes and properties of the RESPIRATORY SYSTEM as a whole or of any of its parts.
The neural systems which act on VASCULAR SMOOTH MUSCLE to control blood vessel diameter. The major neural control is through the sympathetic nervous system.
The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.
Nerves and plexuses of the autonomic nervous system. The central nervous system structures which regulate the autonomic nervous system are not included.
The superior part of the upper extremity between the SHOULDER and the ELBOW.
Sudden occurrence of BRADYCARDIA or HEART ARREST induced by manipulations of the MAXILLARY NERVE AND MANDIBULAR NERVE during a craniomaxillofacial or oral surgery. It is the maxillary and mandibular variants of OCULOCARDIAC REFLEX.
The muscles of the PHARYNX are voluntary muscles arranged in two layers. The external circular layer consists of three constrictors (superior, middle, and inferior). The internal longitudinal layer consists of the palatopharyngeus, the salpingopharyngeus, and the stylopharyngeus. During swallowing, the outer layer constricts the pharyngeal wall and the inner layer elevates pharynx and LARYNX.
Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3).
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
The rotational force about an axis that is equal to the product of a force times the distance from the axis where the force is applied.
The upper part of the human body, or the front or upper part of the body of an animal, typically separated from the rest of the body by a neck, and containing the brain, mouth, and sense organs.
A class of nerve fibers as defined by their nerve sheath arrangement. The AXONS of the unmyelinated nerve fibers are small in diameter and usually several are surrounded by a single MYELIN SHEATH. They conduct low-velocity impulses, and represent the majority of peripheral sensory and autonomic fibers, but are also found in the BRAIN and SPINAL CORD.
The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.
Introduction of therapeutic agents into the spinal region using a needle and syringe.

Babinski response: stimulus and effector. (1/20)

This is an electromyographic study of the activity in flexor and extensor muscles of the big toe in 22 patients with a Babinski sign and 49 controls, after mechanical or electrical stimulation of the sole. The results indicate: (1) the Babinski sign is mediated by the extensor hallucis longus (EHL), and not by the extensor hallucis brevis; (2) electrical stimuli may fail to activate the EHL in these patients, and conversely may evoke EHL reflexes in control subjects; (3) in skin reflexes, electrical and mechanical stimuli are not freely interchangeable.  (+info)

Mechanism of the inverted supinator reflex. A clinical and neurophysiological study. (2/20)

The inverted supinator reflex sign was analysed in two patients by recording the response of the finger flexor muscles of the forearm to tapping of the styloid process of the radius before and after procain infiltration of these muscles. It was found that the response persisted despite the block. The findings support the concept that the underlying mechanism is increased alpha motoneurone excitability below the level of the lesion; however, a possible contribution of the dynamic muscle spindles could not be excluded.  (+info)

The Babinski sign--a reappraisal. (3/20)

In 1896, Joseph Babinski, a French neurologist, first described the best known neurologic eponym 'the Babinski sign'. This sign is characterised by dorsiflexion of the big toe and recruitment of the extensor hallucis longus muscle, on stimulating the sole of the foot. He has emphasised from the outset, the intimate relationship between this sign and the shortening movement in other leg muscles, which form the flexion synergy of the lower limb. The Babinski sign is not a new reflex, rather it is released as a result of breakdown of the harmonious integration of the flexion and extension components of the normal defence reflex mechanism, due to pyramidal tract dysfunction. A pathological Babinski sign should be clearly distinguished from upgoing toes that may not always be a part of the flexion synergy. This article reviews the Babinski sign in detail, focusing on the historical perspectives, role of pyramidal tract dysfunction and art of elicitation and interpretation. The significance of assessing this phenomenon in the entire leg, and the clinical clues that will help to dispel the myths regarding the Babinski sign, have been emphasised.  (+info)

The Babinski sign. (4/20)

Babinski's life and the story of the Babinski sign are summarised. The physiological basis of the sign is discussed.  (+info)

The articles of Babinski on his sign and the paper of 1898. (5/20)

In 1896 Joseph Francois Felix Babinski described for the first time the phenomenon of the toes; nevertheless in this first paper he simply described extension of all toes with pricking of the sole of the foot. It was not until the second paper of 1898 that he specifically described the extension of the hallux with strong tactile stimulation (stroking) of the lateral border of the sole. Babinski probably discovered his sign by a combination of chance observation and careful re-observation and replication. He also had in mind practical applications of the sign, particularly in the differential diagnosis with hysteria and in medico-legal areas. Several of the observations and physiopathological mechanisms proposed by Babinski are still valid today, e.g, he realized since 1896 that the reflex was part of the flexor reflex synergy and observed that several patients during the first hours of an acute cerebral or spinal insult had absent extensor responses. He also found that most patients with the abnormal reflex had weakness of dorsiflexion of the toes and ankles and observed a lack of correlation between hyperactive myotatic reflexes and the presence of an upgoing hallux. He discovered that not all patients with hemiplegia or paraplegia had the sign but thought erroneously that some normal subjects could have an upgoing toe. Between 1896 and 1903 Babinski continued to think on the sign that bears his name and enrich its semiological and physiopathological value.  (+info)

Two Babinski signs in seropositive (HAM) and seronegative tropical spastic paraparesis. (6/20)

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Migraine-like headache and status migrainosus as attacks of multiple sclerosis in a child. (7/20)

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How many Babinski's signs are there? (8/20)

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A reflex is an automatic, involuntary and rapid response to a stimulus that occurs without conscious intention. In the context of physiology and neurology, it's a basic mechanism that involves the transmission of nerve impulses between neurons, resulting in a muscle contraction or glandular secretion.

Reflexes are important for maintaining homeostasis, protecting the body from harm, and coordinating movements. They can be tested clinically to assess the integrity of the nervous system, such as the knee-j jerk reflex, which tests the function of the L3-L4 spinal nerve roots and the sensitivity of the stretch reflex arc.

The Babinski reflex, also known as the plantar reflex, is a physiological response that originates from the spinal cord when the sole of the foot is stimulated. It is named after Joseph François Felix Babinski, a French neurologist who described it in 1896.

In a normal, healthy adult, this stimulation typically results in the downward flexion of the big toe and the fanning out of the other toes. However, in infants and young children, as well as in some individuals with certain neurological conditions, the opposite response may occur - the big toe extends upward (dorsiflexes) while the other toes fan out. This is known as the Babinski reflex and can be a sign of damage to the brain or spinal cord, particularly to the nerve pathways that run from the cortex to the spinal cord.

It's important to note that the presence of an extensor plantar response (Babinski reflex) in adults is considered abnormal and may indicate a neurological disorder such as a brain injury, spinal cord injury, multiple sclerosis, or motor neuron disease. However, it's worth mentioning that certain medications, intoxication, or temporary conditions like sleep deprivation can also cause an abnormal plantar response, so further evaluation is necessary to confirm any diagnosis.

An abnormal reflex in a medical context refers to an involuntary and exaggerated response or lack of response to a stimulus that is not expected in the normal physiological range. These responses can be indicative of underlying neurological disorders or damage to the nervous system. Examples include hyperreflexia (overactive reflexes) and hyporeflexia (underactive reflexes). The assessment of reflexes is an important part of a physical examination, as it can provide valuable information about the functioning of the nervous system.

Neurology is a branch of medicine that deals with the study and treatment of diseases and disorders of the nervous system, which includes the brain, spinal cord, peripheral nerves, muscles, and autonomic nervous system. Neurologists are medical doctors who specialize in this field, diagnosing and treating conditions such as stroke, Alzheimer's disease, epilepsy, Parkinson's disease, multiple sclerosis, and various types of headaches and pain disorders. They use a variety of diagnostic tests, including imaging studies like MRI and CT scans, electrophysiological tests like EEG and EMG, and laboratory tests to evaluate nerve function and identify any underlying conditions or abnormalities. Treatment options may include medication, surgery, rehabilitation, or lifestyle modifications.

"History, 19th Century" is not a medical term or concept. It refers to the historical events, developments, and figures related to the 1800s in various fields, including politics, culture, science, and technology. However, if you are looking for medical advancements during the 19th century, here's a brief overview:

The 19th century was a period of significant progress in medicine, with numerous discoveries and innovations that shaped modern medical practices. Some notable developments include:

1. Edward Jenner's smallpox vaccine (1796): Although not strictly within the 19th century, Jenner's discovery laid the foundation for vaccination as a preventive measure against infectious diseases.
2. Germ theory of disease: The work of Louis Pasteur, Robert Koch, and others established that many diseases were caused by microorganisms, leading to the development of antiseptic practices and vaccines.
3. Anesthesia: In 1842, Crawford Long first used ether as an anesthetic during surgery, followed by the introduction of chloroform in 1847 by James Simpson.
4. Antisepsis and asepsis: Joseph Lister introduced antiseptic practices in surgery, significantly reducing postoperative infections. Later, the concept of asepsis (sterilization) was developed to prevent contamination during surgical procedures.
5. Microbiology: The development of techniques for culturing and staining bacteria allowed for better understanding and identification of pathogens.
6. Physiology: Claude Bernard's work on the regulation of internal body functions, or homeostasis, contributed significantly to our understanding of human physiology.
7. Neurology: Jean-Martin Charcot made significant contributions to the study of neurological disorders, including multiple sclerosis and Parkinson's disease.
8. Psychiatry: Sigmund Freud developed psychoanalysis, a new approach to understanding mental illnesses.
9. Public health: The 19th century saw the establishment of public health organizations and initiatives aimed at improving sanitation, water quality, and vaccination programs.
10. Medical education reforms: The Flexner Report in 1910 led to significant improvements in medical education standards and practices.

An eponym is a name derived from a person, usually the person who first described a medical condition or invention. In medicine, eponyms are often used to describe specific signs, symptoms, conditions, or diagnostic tests. For example, Alzheimer's disease is named after Alois Alzheimer, who first described the condition in 1906. Similarly, Parkinson's disease is named after James Parkinson, who first described it in 1817.

Eponyms can be helpful in medical communication because they provide a quick and easy way to refer to specific medical concepts. However, they can also be confusing or misleading, especially when the eponym's origin is not well-known or when different eponyms are used for the same concept. Therefore, it is essential to use eponyms appropriately and understand their underlying medical concepts.

In medical terms, toes are the digits located at the end of the foot. Humans typically have five toes on each foot, consisting of the big toe (hallux), second toe, third toe, fourth toe, and little toe (fifth toe). The bones of the toes are called phalanges, with the exception of the big toe, which has a different bone structure and is composed of a proximal phalanx, distal phalanx, and sometimes a sesamoid bone.

Toes play an essential role in maintaining balance and assisting in locomotion by helping to push off the ground during walking or running. They also contribute to the overall stability and posture of the body. Various medical conditions can affect toes, such as ingrown toenails, bunions, hammertoes, and neuromas, which may require specific treatments or interventions to alleviate pain, restore function, or improve appearance.

The pyramidal tracts, also known as the corticospinal tracts, are bundles of nerve fibers that run through the brainstem and spinal cord, originating from the cerebral cortex. These tracts are responsible for transmitting motor signals from the brain to the muscles, enabling voluntary movement and control of the body.

The pyramidal tracts originate from the primary motor cortex in the frontal lobe of the brain and decussate (cross over) in the lower medulla oblongata before continuing down the spinal cord. The left pyramidal tract controls muscles on the right side of the body, while the right pyramidal tract controls muscles on the left side of the body.

Damage to the pyramidal tracts can result in various motor impairments, such as weakness or paralysis, spasticity, and loss of fine motor control, depending on the location and extent of the damage.

A stretch reflex, also known as myotatic reflex, is a rapid muscle contraction in response to stretching within the muscle itself. It is a type of reflex that helps to maintain muscle tone, protect muscles and tendons from injury, and assists in coordinating movements.

The stretch reflex is mediated by the stretch (or length) receptors called muscle spindles, which are located within the muscle fibers. When a muscle is stretched suddenly or rapidly, the muscle spindles detect the change in muscle length and activate a rapid motor neuron response, leading to muscle contraction. This reflex helps to stabilize the joint and prevent further stretching or injury.

The most common example of a stretch reflex is the knee-jerk reflex (also known as the patellar reflex), which is elicited by tapping the patellar tendon just below the knee, causing the quadriceps muscle to stretch and contract. This results in a quick extension of the lower leg. Other examples of stretch reflexes include the ankle jerk reflex (Achilles reflex) and the biceps reflex.

I'm sorry for any confusion, but "History, 20th Century" is a broad and complex topic that refers to the events, developments, and transformations that occurred throughout the world during the 1900s. It is not a medical term or concept. If you're interested in learning more about this historical period, I would recommend consulting a history textbook, reputable online resources, or speaking with a historian. They can provide detailed information about the political, social, economic, and cultural changes that took place during the 20th century.

Nervous system diseases, also known as neurological disorders, refer to a group of conditions that affect the nervous system, which includes the brain, spinal cord, nerves, and muscles. These diseases can affect various functions of the body, such as movement, sensation, cognition, and behavior. They can be caused by genetics, infections, injuries, degeneration, or tumors. Examples of nervous system diseases include Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, migraine, stroke, and neuroinfections like meningitis and encephalitis. The symptoms and severity of these disorders can vary widely, ranging from mild to severe and debilitating.

A "reflex, acoustic" is not a standard medical term. However, it seems like you might be looking for a definition of the "acoustic reflex." The acoustic reflex is an involuntary muscle contraction that occurs in the middle ear in response to loud sounds. This reflex helps protect the inner ear from damage caused by high-intensity sounds.

When a loud sound reaches the ear, it stimulates the stapedius muscle in the middle ear, which then contracts and causes the stapes bone (one of the three bones in the middle ear) to become stiffer. This stiffening reduces the amount of sound that is transmitted to the inner ear, thus protecting it from potential harm.

The acoustic reflex can be measured using a device called an impedance audiometer, which measures changes in the pressure within the ear canal caused by muscle contraction during the reflex. This measurement provides valuable information for diagnosing and monitoring various hearing and balance disorders.

A vestibulo-ocular reflex (VOR) is a automatic motion of the eyes that helps to stabilize images on the retina during head movement. It is mediated by the vestibular system, which includes the semicircular canals and otolith organs in the inner ear.

When the head moves, the movement is detected by the vestibular system, which sends signals to the oculomotor nuclei in the brainstem. These nuclei then generate an eye movement that is equal and opposite to the head movement, allowing the eyes to remain fixed on a target while the head is moving. This reflex helps to maintain visual stability during head movements and is essential for activities such as reading, walking, and driving.

The VOR can be tested clinically by having the patient follow a target with their eyes while their head is moved passively. If the VOR is functioning properly, the eyes should remain fixed on the target despite the head movement. Abnormalities in the VOR can indicate problems with the vestibular system or the brainstem.

A pupillary reflex is a type of reflex that involves the constriction or dilation of the pupils in response to changes in light or near vision. It is mediated by the optic and oculomotor nerves. The pupillary reflex helps regulate the amount of light that enters the eye, improving visual acuity and protecting the retina from excessive light exposure.

In a clinical setting, the pupillary reflex is often assessed as part of a neurological examination. A normal pupillary reflex consists of both direct and consensual responses. The direct response occurs when light is shone into one eye and the pupil of that same eye constricts. The consensual response occurs when light is shone into one eye, causing the pupil of the other eye to also constrict.

Abnormalities in the pupillary reflex can indicate various neurological conditions, such as brainstem injuries or diseases affecting the optic or oculomotor nerves.

Electromyography (EMG) is a medical diagnostic procedure that measures the electrical activity of skeletal muscles during contraction and at rest. It involves inserting a thin needle electrode into the muscle to record the electrical signals generated by the muscle fibers. These signals are then displayed on an oscilloscope and may be heard through a speaker.

EMG can help diagnose various neuromuscular disorders, such as muscle weakness, numbness, or pain, and can distinguish between muscle and nerve disorders. It is often used in conjunction with other diagnostic tests, such as nerve conduction studies, to provide a comprehensive evaluation of the nervous system.

EMG is typically performed by a neurologist or a physiatrist, and the procedure may cause some discomfort or pain, although this is usually minimal. The results of an EMG can help guide treatment decisions and monitor the progression of neuromuscular conditions over time.

A decerebrate state is a medical condition that results from severe damage to the brainstem, specifically to the midbrain and above. This type of injury can cause motor responses characterized by rigid extension of the arms and legs, with the arms rotated outward and the wrists and fingers extended. The legs are also extended and the toes pointed downward. These postures are often referred to as "decerebrate rigidity" or "posturing."

The decerebrate state is typically seen in patients who have experienced severe trauma, such as a car accident or gunshot wound, or who have suffered from a large stroke or other type of brain hemorrhage. It can also occur in some cases of severe hypoxia (lack of oxygen) to the brain, such as during cardiac arrest or drowning.

The decerebrate state is a serious medical emergency that requires immediate treatment. If left untreated, it can lead to further brain damage and even death. Treatment typically involves providing supportive care, such as mechanical ventilation to help with breathing, medications to control blood pressure and prevent seizures, and surgery to repair any underlying injuries or bleeding. In some cases, patients may require long-term rehabilitation to regain lost function and improve their quality of life.

The H-reflex, or Hoffmann reflex, is a monosynaptic reflex that tests the integrity of the Ia afferent nerve fibers and the corresponding alpha motor neurons in the spinal cord. It's often used in clinical and research settings to assess the function of the lower motor neuron and the sensitivity of the stretch reflex.

The H-reflex is elicited by applying an electrical stimulus to a sensory nerve, typically the tibial nerve at the popliteal fossa or the median nerve at the wrist. This stimulation activates Ia afferent fibers, which then synapse directly onto alpha motor neurons in the spinal cord, causing a muscle contraction in the corresponding agonist muscle (e.g., soleus or flexor carpi radialis). The latency of the H-reflex provides information about the conduction velocity of Ia afferent fibers and the excitability of alpha motor neurons.

It's important to note that the H-reflex is influenced by various factors, such as muscle length, contraction state, and the overall excitability of the nervous system. Therefore, interpreting H-reflex results requires a thorough understanding of these influencing factors and careful consideration of the clinical context.

A righting reflex is a type of involuntary response that helps to maintain the body's position and orientation in space. These reflexes are critical for maintaining balance and preventing falls, especially during movement.

Righting reflexes involve a complex network of sensory receptors, including those in the inner ear, muscles, joints, and skin, which detect changes in the body's position or orientation. When these receptors detect a change, they send signals to the brainstem, which rapidly activates specific muscle groups to restore balance and maintain an upright posture.

Examples of righting reflexes include:

* The labyrinthine righting reflex, which helps to keep the head in a stable position relative to the body, even when the body is moving or changing position.
* The tonic neck reflex, which causes the arms and legs to extend when the head is turned to one side.
* The asymmetrical tonic neck reflex, which causes the arm and leg on the same side as the head turn to bend, while the opposite limbs extend.

Righting reflexes are present from birth and are critical for normal motor development. However, they can also be affected by brainstem or cerebellar injuries, leading to balance and coordination problems.

An oculocardiac reflex is a medical term that refers to a reflexive response that involves the eye and the heart. This reflex is elicited when there is pressure or traction applied to the eye or its surrounding structures, which can result in a decrease in heart rate.

The oculocardiac reflex is mediated by the ophthalmic division of the trigeminal nerve (cranial nerve V) and the vagus nerve (cranial nerve X). When the eye or its surrounding structures are stimulated, the impulses travel through the ophthalmic branch of the trigeminal nerve to the brainstem, where they synapse with neurons in the vagus nerve. The vagus nerve then carries these impulses to the sinoatrial node of the heart, which results in a decrease in heart rate.

The oculocardiac reflex is commonly seen during ophthalmic surgical procedures, particularly those that involve manipulation of the eye or its surrounding structures. It can also occur in response to other forms of stimulation, such as coughing, sneezing, or vomiting. In some cases, the oculocardiac reflex can lead to a significant decrease in heart rate, which may require medical intervention to prevent serious complications.

Pressoreceptors are specialized sensory nerve endings found in the walls of blood vessels, particularly in the carotid sinus and aortic arch. They respond to changes in blood pressure by converting the mechanical stimulus into electrical signals that are transmitted to the brain. This information helps regulate cardiovascular function and maintain blood pressure homeostasis.

Blinking is the rapid and repetitive closing and reopening of the eyelids. It is a normal physiological process that helps to keep the eyes moist, protected and comfortable by spreading tears over the surface of the eye and removing any foreign particles or irritants that may have accumulated on the eyelid or the conjunctiva (the mucous membrane that covers the front of the eye and lines the inside of the eyelids).

Blinking is controlled by the facial nerve (cranial nerve VII), which sends signals to the muscles that control the movement of the eyelids. On average, people blink about 15-20 times per minute, but this rate can vary depending on factors such as mood, level of attention, and visual tasks. For example, people tend to blink less frequently when they are concentrating on a visual task or looking at a screen, which can lead to dry eye symptoms.

An abdominal reflex is a withdrawal response that occurs when the skin in the lower abdomen is stimulated, leading to contraction of the muscles in the same side of the abdomen. This reflex is mediated by the T10-L1 spinal cord segments and is typically tested during a physical examination to assess the integrity of the nervous system. A decreased or absent abdominal reflex may indicate damage to the peripheral nerves, spinal cord, or brain.

"Cat" is a common name that refers to various species of small carnivorous mammals that belong to the family Felidae. The domestic cat, also known as Felis catus or Felis silvestris catus, is a popular pet and companion animal. It is a subspecies of the wildcat, which is found in Europe, Africa, and Asia.

Domestic cats are often kept as pets because of their companionship, playful behavior, and ability to hunt vermin. They are also valued for their ability to provide emotional support and therapy to people. Cats are obligate carnivores, which means that they require a diet that consists mainly of meat to meet their nutritional needs.

Cats are known for their agility, sharp senses, and predatory instincts. They have retractable claws, which they use for hunting and self-defense. Cats also have a keen sense of smell, hearing, and vision, which allow them to detect prey and navigate their environment.

In medical terms, cats can be hosts to various parasites and diseases that can affect humans and other animals. Some common feline diseases include rabies, feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and toxoplasmosis. It is important for cat owners to keep their pets healthy and up-to-date on vaccinations and preventative treatments to protect both the cats and their human companions.

Electric stimulation, also known as electrical nerve stimulation or neuromuscular electrical stimulation, is a therapeutic treatment that uses low-voltage electrical currents to stimulate nerves and muscles. It is often used to help manage pain, promote healing, and improve muscle strength and mobility. The electrical impulses can be delivered through electrodes placed on the skin or directly implanted into the body.

In a medical context, electric stimulation may be used for various purposes such as:

1. Pain management: Electric stimulation can help to block pain signals from reaching the brain and promote the release of endorphins, which are natural painkillers produced by the body.
2. Muscle rehabilitation: Electric stimulation can help to strengthen muscles that have become weak due to injury, illness, or surgery. It can also help to prevent muscle atrophy and improve range of motion.
3. Wound healing: Electric stimulation can promote tissue growth and help to speed up the healing process in wounds, ulcers, and other types of injuries.
4. Urinary incontinence: Electric stimulation can be used to strengthen the muscles that control urination and reduce symptoms of urinary incontinence.
5. Migraine prevention: Electric stimulation can be used as a preventive treatment for migraines by applying electrical impulses to specific nerves in the head and neck.

It is important to note that electric stimulation should only be administered under the guidance of a qualified healthcare professional, as improper use can cause harm or discomfort.

"Gagging" is a reflexive response to an irritation or stimulation of the back of the throat, which involves involuntary contraction of the muscles at the back of the throat and sometimes accompanied by vomiting. It is a protective mechanism to prevent foreign objects from entering the lungs during swallowing. In a medical context, gagging may also refer to the use of a device or maneuver to temporarily block the upper airway as part of certain medical procedures.

Reflex epilepsy is a type of epilepsy in which seizures are consistently triggered by specific, recurring sensory stimuli. These triggers can vary widely and may include visual patterns, flashes of light, touch, sound, or even emotional experiences. When the brain receives input from these triggers, it responds with an abnormal electrical discharge that can lead to a seizure.

Reflex epilepsy is relatively rare, accounting for only about 5-10% of all epilepsy cases. It's important to note that not everyone who experiences seizures in response to these triggers has reflex epilepsy; the defining characteristic of this condition is the consistent and reproducible nature of the seizure response to a specific stimulus.

There are several different types of reflex epilepsy, each characterized by its own unique set of triggers. For example, some people with this condition may experience seizures in response to visual patterns or flashes of light (known as photosensitive epilepsy), while others may have seizures triggered by certain sounds or tactile sensations.

Treatment for reflex epilepsy typically involves identifying and avoiding triggers whenever possible, as well as using medication to control seizures. In some cases, surgery may be recommended to remove the specific area of the brain that is responsible for the abnormal electrical activity. With proper treatment and management, many people with reflex epilepsy are able to lead full and active lives.

The vagus nerve, also known as the 10th cranial nerve (CN X), is the longest of the cranial nerves and extends from the brainstem to the abdomen. It has both sensory and motor functions and plays a crucial role in regulating various bodily functions such as heart rate, digestion, respiratory rate, speech, and sweating, among others.

The vagus nerve is responsible for carrying sensory information from the internal organs to the brain, and it also sends motor signals from the brain to the muscles of the throat and voice box, as well as to the heart, lungs, and digestive tract. The vagus nerve helps regulate the body's involuntary responses, such as controlling heart rate and blood pressure, promoting relaxation, and reducing inflammation.

Dysfunction in the vagus nerve can lead to various medical conditions, including gastroparesis, chronic pain, and autonomic nervous system disorders. Vagus nerve stimulation (VNS) is a therapeutic intervention that involves delivering electrical impulses to the vagus nerve to treat conditions such as epilepsy, depression, and migraine headaches.

Afferent neurons, also known as sensory neurons, are a type of nerve cell that conducts impulses or signals from peripheral receptors towards the central nervous system (CNS), which includes the brain and spinal cord. These neurons are responsible for transmitting sensory information such as touch, temperature, pain, sound, and light to the CNS for processing and interpretation. Afferent neurons have specialized receptor endings that detect changes in the environment and convert them into electrical signals, which are then transmitted to the CNS via synapses with other neurons. Once the signals reach the CNS, they are processed and integrated with other information to produce a response or reaction to the stimulus.

Afferent pathways, also known as sensory pathways, refer to the neural connections that transmit sensory information from the peripheral nervous system to the central nervous system (CNS), specifically to the brain and spinal cord. These pathways are responsible for carrying various types of sensory information, such as touch, temperature, pain, pressure, vibration, hearing, vision, and taste, to the CNS for processing and interpretation.

The afferent pathways begin with sensory receptors located throughout the body, which detect changes in the environment and convert them into electrical signals. These signals are then transmitted via afferent neurons, also known as sensory neurons, to the spinal cord or brainstem. Within the CNS, the information is further processed and integrated with other neural inputs before being relayed to higher cognitive centers for conscious awareness and response.

Understanding the anatomy and physiology of afferent pathways is essential for diagnosing and treating various neurological conditions that affect sensory function, such as neuropathies, spinal cord injuries, and brain disorders.

Mechanoreceptors are specialized sensory receptor cells that convert mechanical stimuli such as pressure, tension, or deformation into electrical signals that can be processed and interpreted by the nervous system. They are found in various tissues throughout the body, including the skin, muscles, tendons, joints, and internal organs. Mechanoreceptors can detect different types of mechanical stimuli depending on their specific structure and location. For example, Pacinian corpuscles in the skin respond to vibrations, while Ruffini endings in the joints detect changes in joint angle and pressure. Overall, mechanoreceptors play a crucial role in our ability to perceive and interact with our environment through touch, proprioception (the sense of the position and movement of body parts), and visceral sensation (awareness of internal organ activity).

Motor neurons are specialized nerve cells in the brain and spinal cord that play a crucial role in controlling voluntary muscle movements. They transmit electrical signals from the brain to the muscles, enabling us to perform actions such as walking, talking, and swallowing. There are two types of motor neurons: upper motor neurons, which originate in the brain's motor cortex and travel down to the brainstem and spinal cord; and lower motor neurons, which extend from the brainstem and spinal cord to the muscles. Damage or degeneration of these motor neurons can lead to various neurological disorders, such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).

Reflex Sympathetic Dystrophy (RSD), also known as Complex Regional Pain Syndrome (CRPS), is a chronic pain condition that most often affects a limb after an injury or trauma. It is characterized by prolonged or excessive pain and sensitivity, along with changes in skin color, temperature, and swelling.

The symptoms of RSD/CRPS are thought to be caused by an overactive sympathetic nervous system, which controls involuntary bodily functions such as heart rate, blood pressure, and sweating. In RSD/CRPS, the sympathetic nerves are believed to send incorrect signals to the brain, causing it to perceive intense pain even in the absence of any actual tissue damage.

RSD/CRPS can be classified into two types: Type 1, which occurs after an injury or trauma that did not directly damage the nerves, and Type 2, which occurs after a distinct nerve injury. The symptoms of both types are similar, but Type 2 is typically more severe and may involve more widespread nerve damage.

Treatment for RSD/CRPS usually involves a combination of medications, physical therapy, and other therapies such as spinal cord stimulation or sympathetic nerve blocks. Early diagnosis and treatment can help improve outcomes and reduce the risk of long-term complications.

The baroreflex is a physiological mechanism that helps regulate blood pressure and heart rate in response to changes in stretch of the arterial walls. It is mediated by baroreceptors, which are specialized sensory nerve endings located in the carotid sinus and aortic arch. These receptors detect changes in blood pressure and send signals to the brainstem via the glossopharyngeal (cranial nerve IX) and vagus nerves (cranial nerve X), respectively.

In response to an increase in arterial pressure, the baroreceptors are stimulated, leading to increased firing of afferent neurons that signal the brainstem. This results in a reflexive decrease in heart rate and cardiac output, as well as vasodilation of peripheral blood vessels, which collectively work to reduce blood pressure back towards its normal level. Conversely, if arterial pressure decreases, the baroreceptors are less stimulated, leading to an increase in heart rate and cardiac output, as well as vasoconstriction of peripheral blood vessels, which helps restore blood pressure.

Overall, the baroreflex is a crucial homeostatic mechanism that helps maintain stable blood pressure and ensure adequate perfusion of vital organs.

Physical stimulation, in a medical context, refers to the application of external forces or agents to the body or its tissues to elicit a response. This can include various forms of touch, pressure, temperature, vibration, or electrical currents. The purpose of physical stimulation may be therapeutic, as in the case of massage or physical therapy, or diagnostic, as in the use of reflex tests. It is also used in research settings to study physiological responses and mechanisms.

In a broader sense, physical stimulation can also refer to the body's exposure to physical activity or exercise, which can have numerous health benefits, including improving cardiovascular function, increasing muscle strength and flexibility, and reducing the risk of chronic diseases.

Muscle contraction is the physiological process in which muscle fibers shorten and generate force, leading to movement or stability of a body part. This process involves the sliding filament theory where thick and thin filaments within the sarcomeres (the functional units of muscles) slide past each other, facilitated by the interaction between myosin heads and actin filaments. The energy required for this action is provided by the hydrolysis of adenosine triphosphate (ATP). Muscle contractions can be voluntary or involuntary, and they play a crucial role in various bodily functions such as locomotion, circulation, respiration, and posture maintenance.

Efferent neurons are specialized nerve cells that transmit signals from the central nervous system (CNS), which includes the brain and spinal cord, to effector organs such as muscles or glands. These signals typically result in a response or action, hence the term "efferent," derived from the Latin word "efferre" meaning "to carry away."

Efferent neurons are part of the motor pathway and can be further classified into two types:

1. Somatic efferent neurons: These neurons transmit signals to skeletal muscles, enabling voluntary movements and posture maintenance. They have their cell bodies located in the ventral horn of the spinal cord and send their axons through the ventral roots to innervate specific muscle fibers.
2. Autonomic efferent neurons: These neurons are responsible for controlling involuntary functions, such as heart rate, digestion, respiration, and pupil dilation. They have a two-neuron chain arrangement, with the preganglionic neuron having its cell body in the CNS (brainstem or spinal cord) and synapsing with the postganglionic neuron in an autonomic ganglion near the effector organ. Autonomic efferent neurons can be further divided into sympathetic, parasympathetic, and enteric subdivisions based on their functions and innervation patterns.

In summary, efferent neurons are a critical component of the nervous system, responsible for transmitting signals from the CNS to various effector organs, ultimately controlling and coordinating numerous bodily functions and responses.

Heart rate is the number of heartbeats per unit of time, often expressed as beats per minute (bpm). It can vary significantly depending on factors such as age, physical fitness, emotions, and overall health status. A resting heart rate between 60-100 bpm is generally considered normal for adults, but athletes and individuals with high levels of physical fitness may have a resting heart rate below 60 bpm due to their enhanced cardiovascular efficiency. Monitoring heart rate can provide valuable insights into an individual's health status, exercise intensity, and response to various treatments or interventions.

The sympathetic nervous system (SNS) is a part of the autonomic nervous system that operates largely below the level of consciousness, and it functions to produce appropriate physiological responses to perceived danger. It's often associated with the "fight or flight" response. The SNS uses nerve impulses to stimulate target organs, causing them to speed up (e.g., increased heart rate), prepare for action, or otherwise respond to stressful situations.

The sympathetic nervous system is activated due to stressful emotional or physical situations and it prepares the body for immediate actions. It dilates the pupils, increases heart rate and blood pressure, accelerates breathing, and slows down digestion. The primary neurotransmitter involved in this system is norepinephrine (also known as noradrenaline).

The carotid sinus is a small, dilated area located at the bifurcation (or fork) of the common carotid artery into the internal and external carotid arteries. It is a baroreceptor region, which means it contains specialized sensory nerve endings that can detect changes in blood pressure. When the blood pressure increases, the walls of the carotid sinus stretch, activating these nerve endings and sending signals to the brain. The brain then responds by reducing the heart rate and relaxing the blood vessels, which helps to lower the blood pressure back to normal.

The carotid sinus is an important part of the body's autonomic nervous system, which regulates various involuntary functions such as heart rate, blood pressure, and digestion. It plays a crucial role in maintaining cardiovascular homeostasis and preventing excessive increases in blood pressure that could potentially damage vital organs.

The trigeminal nerve, also known as the fifth cranial nerve or CNV, is a paired nerve that carries both sensory and motor information. It has three major branches: ophthalmic (V1), maxillary (V2), and mandibular (V3). The ophthalmic branch provides sensation to the forehead, eyes, and upper portion of the nose; the maxillary branch supplies sensation to the lower eyelid, cheek, nasal cavity, and upper lip; and the mandibular branch is responsible for sensation in the lower lip, chin, and parts of the oral cavity, as well as motor function to the muscles involved in chewing. The trigeminal nerve plays a crucial role in sensations of touch, pain, temperature, and pressure in the face and mouth, and it also contributes to biting, chewing, and swallowing functions.

The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.

The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.

The spinal cord is responsible for several vital functions, including:

1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.

Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.

The Tibial nerve is a major branch of the sciatic nerve that originates in the lower back and runs through the buttock and leg. It provides motor (nerve impulses that control muscle movement) and sensory (nerve impulses that convey information about touch, temperature, and pain) innervation to several muscles and skin regions in the lower limb.

More specifically, the Tibial nerve supplies the following structures:

1. Motor Innervation: The Tibial nerve provides motor innervation to the muscles in the back of the leg (posterior compartment), including the calf muscles (gastrocnemius and soleus) and the small muscles in the foot (intrinsic muscles). These muscles are responsible for plantarflexion (pointing the foot downward) and inversion (turning the foot inward) of the foot.
2. Sensory Innervation: The Tibial nerve provides sensory innervation to the skin on the sole of the foot, as well as the heel and some parts of the lower leg.

The Tibial nerve travels down the leg, passing behind the knee and through the calf, where it eventually joins with the common fibular (peroneal) nerve to form the tibial-fibular trunk. This trunk then divides into several smaller nerves that innervate the foot's intrinsic muscles and skin.

Damage or injury to the Tibial nerve can result in various symptoms, such as weakness or paralysis of the calf and foot muscles, numbness or tingling sensations in the sole of the foot, and difficulty walking or standing on tiptoes.

Urination, also known as micturition, is the physiological process of excreting urine from the urinary bladder through the urethra. It is a complex process that involves several systems in the body, including the urinary system, nervous system, and muscular system.

In medical terms, urination is defined as the voluntary or involuntary discharge of urine from the urethra, which is the final pathway for the elimination of waste products from the body. The process is regulated by a complex interplay between the detrusor muscle of the bladder, the internal and external sphincters of the urethra, and the nervous system.

During urination, the detrusor muscle contracts, causing the bladder to empty, while the sphincters relax to allow the urine to flow through the urethra and out of the body. The nervous system plays a crucial role in coordinating these actions, with sensory receptors in the bladder sending signals to the brain when it is time to urinate.

Urination is essential for maintaining the balance of fluids and electrolytes in the body, as well as eliminating waste products such as urea, creatinine, and other metabolic byproducts. Abnormalities in urination can indicate underlying medical conditions, such as urinary tract infections, bladder dysfunction, or neurological disorders.

Blood pressure is the force exerted by circulating blood on the walls of the blood vessels. It is measured in millimeters of mercury (mmHg) and is given as two figures:

1. Systolic pressure: This is the pressure when the heart pushes blood out into the arteries.
2. Diastolic pressure: This is the pressure when the heart rests between beats, allowing it to fill with blood.

Normal blood pressure for adults is typically around 120/80 mmHg, although this can vary slightly depending on age, sex, and other factors. High blood pressure (hypertension) is generally considered to be a reading of 130/80 mmHg or higher, while low blood pressure (hypotension) is usually defined as a reading below 90/60 mmHg. It's important to note that blood pressure can fluctuate throughout the day and may be affected by factors such as stress, physical activity, and medication use.

A vagotomy is a surgical procedure that involves cutting or blocking the vagus nerve, which is a parasympathetic nerve that runs from the brainstem to the abdomen and helps regulate many bodily functions such as heart rate, gastrointestinal motility, and digestion. In particular, vagotomy is often performed as a treatment for peptic ulcers, as it can help reduce gastric acid secretion.

There are several types of vagotomy procedures, including:

1. Truncal vagotomy: This involves cutting the main trunks of the vagus nerve as they enter the abdomen. It is a more extensive procedure that reduces gastric acid secretion significantly but can also lead to side effects such as delayed gastric emptying and diarrhea.
2. Selective vagotomy: This involves cutting only the branches of the vagus nerve that supply the stomach, leaving the rest of the nerve intact. It is a less extensive procedure that reduces gastric acid secretion while minimizing side effects.
3. Highly selective vagotomy (HSV): Also known as parietal cell vagotomy, this involves cutting only the branches of the vagus nerve that supply the acid-secreting cells in the stomach. It is a highly targeted procedure that reduces gastric acid secretion while minimizing side effects such as delayed gastric emptying and diarrhea.

Vagotomy is typically performed using laparoscopic or open surgical techniques, depending on the patient's individual needs and the surgeon's preference. While vagotomy can be effective in treating peptic ulcers, it is not commonly performed today due to the development of less invasive treatments such as proton pump inhibitors (PPIs) that reduce gastric acid secretion without surgery.

The vestibular system is a part of the inner ear that contributes to our sense of balance and spatial orientation. It is made up of two main components: the vestibule and the labyrinth.

The vestibule is a bony chamber in the inner ear that contains two important structures called the utricle and saccule. These structures contain hair cells and fluid-filled sacs that help detect changes in head position and movement, allowing us to maintain our balance and orientation in space.

The labyrinth, on the other hand, is a more complex structure that includes the vestibule as well as three semicircular canals. These canals are also filled with fluid and contain hair cells that detect rotational movements of the head. Together, the vestibule and labyrinth work together to provide us with information about our body's position and movement in space.

Overall, the vestibular system plays a crucial role in maintaining our balance, coordinating our movements, and helping us navigate through our environment.

Skeletal muscle, also known as striated or voluntary muscle, is a type of muscle that is attached to bones by tendons or aponeuroses and functions to produce movements and support the posture of the body. It is composed of long, multinucleated fibers that are arranged in parallel bundles and are characterized by alternating light and dark bands, giving them a striped appearance under a microscope. Skeletal muscle is under voluntary control, meaning that it is consciously activated through signals from the nervous system. It is responsible for activities such as walking, running, jumping, and lifting objects.

Chemoreceptor cells are specialized sensory neurons that detect and respond to chemical changes in the internal or external environment. They play a crucial role in maintaining homeostasis within the body by converting chemical signals into electrical impulses, which are then transmitted to the central nervous system for further processing and response.

There are two main types of chemoreceptor cells:

1. Oxygen Chemoreceptors: These cells are located in the carotid bodies near the bifurcation of the common carotid artery and in the aortic bodies close to the aortic arch. They monitor the levels of oxygen, carbon dioxide, and pH in the blood and respond to decreases in oxygen concentration or increases in carbon dioxide and hydrogen ions (indicating acidity) by increasing their firing rate. This signals the brain to increase respiratory rate and depth, thereby restoring normal oxygen levels.

2. Taste Cells: These chemoreceptor cells are found within the taste buds of the tongue and other areas of the oral cavity. They detect specific tastes (salty, sour, sweet, bitter, and umami) by interacting with molecules from food. When a tastant binds to receptors on the surface of a taste cell, it triggers a series of intracellular signaling events that ultimately lead to the generation of an action potential. This information is then relayed to the brain, where it is interpreted as taste sensation.

In summary, chemoreceptor cells are essential for maintaining physiological balance by detecting and responding to chemical stimuli in the body. They play a critical role in regulating vital functions such as respiration and digestion.

The laryngeal nerves are a pair of nerves that originate from the vagus nerve (cranial nerve X) and provide motor and sensory innervation to the larynx. There are two branches of the laryngeal nerves: the superior laryngeal nerve and the recurrent laryngeal nerve.

The superior laryngeal nerve has two branches: the external branch, which provides motor innervation to the cricothyroid muscle and sensation to the mucous membrane of the laryngeal vestibule; and the internal branch, which provides sensory innervation to the mucous membrane of the laryngeal vestibule.

The recurrent laryngeal nerve provides motor innervation to all the intrinsic muscles of the larynx, except for the cricothyroid muscle, and sensation to the mucous membrane below the vocal folds. The right recurrent laryngeal nerve has a longer course than the left one, as it hooks around the subclavian artery before ascending to the larynx.

Damage to the laryngeal nerves can result in voice changes, difficulty swallowing, and respiratory distress.

Capsaicin is defined in medical terms as the active component of chili peppers (genus Capsicum) that produces a burning sensation when it comes into contact with mucous membranes or skin. It is a potent irritant and is used topically as a counterirritant in some creams and patches to relieve pain. Capsaicin works by depleting substance P, a neurotransmitter that relays pain signals to the brain, from nerve endings.

Here is the medical definition of capsaicin from the Merriam-Webster's Medical Dictionary:

caпсаісіn : an alkaloid (C18H27NO3) that is the active principle of red peppers and is used in topical preparations as a counterirritant and analgesic.

Muscle spasticity is a motor disorder characterized by an involuntary increase in muscle tone, leading to stiffness and difficulty in moving muscles. It is often seen in people with damage to the brain or spinal cord, such as those with cerebral palsy, multiple sclerosis, or spinal cord injuries.

In muscle spasticity, the muscles may contract excessively, causing rigid limbs, awkward movements, and abnormal postures. The severity of muscle spasticity can vary from mild stiffness to severe contractures that limit mobility and function.

Muscle spasticity is caused by an imbalance between excitatory and inhibitory signals in the central nervous system, leading to overactivity of the alpha motor neurons that control muscle contraction. This can result in hyperreflexia (overactive reflexes), clonus (rapid, rhythmic muscle contractions), and flexor or extensor spasms.

Effective management of muscle spasticity may involve a combination of physical therapy, medication, surgery, or other interventions to improve function, reduce pain, and prevent complications such as contractures and pressure sores.

Biguanides are a class of oral hypoglycemic agents used in the treatment of type 2 diabetes. The primary mechanism of action of biguanides is to decrease hepatic glucose production and increase insulin sensitivity, which leads to reduced fasting glucose levels and improved glycemic control.

The most commonly prescribed biguanide is metformin, which has been widely used for several decades due to its efficacy and low risk of hypoglycemia. Other biguanides include phenformin and buformin, but these are rarely used due to their association with a higher risk of lactic acidosis, a potentially life-threatening complication.

In addition to their glucose-lowering effects, biguanides have also been shown to have potential benefits on cardiovascular health and weight management, making them a valuable treatment option for many individuals with type 2 diabetes. However, they should be used with caution in patients with impaired renal function or other underlying medical conditions that may increase the risk of lactic acidosis.

The sural nerve is a purely sensory peripheral nerve in the lower leg and foot. It provides sensation to the outer ( lateral) aspect of the little toe and the adjacent side of the fourth toe, as well as a small portion of the skin on the back of the leg between the ankle and knee joints.

The sural nerve is formed by the union of branches from the tibial and common fibular nerves (branches of the sciatic nerve) in the lower leg. It runs down the calf, behind the lateral malleolus (the bony prominence on the outside of the ankle), and into the foot.

The sural nerve is often used as a donor nerve during nerve grafting procedures due to its consistent anatomy and relatively low risk for morbidity at the donor site.

Muscle spindles are specialized sensory organs found within the muscle belly, which primarily function as proprioceptors, providing information about the length and rate of change in muscle length. They consist of small, encapsulated bundles of intrafusal muscle fibers that are interspersed among the extrafusal muscle fibers (the ones responsible for force generation).

Muscle spindles have two types of sensory receptors called primary and secondary endings. Primary endings are located near the equatorial region of the intrafusal fiber, while secondary endings are situated more distally. These endings detect changes in muscle length and transmit this information to the central nervous system (CNS) through afferent nerve fibers.

The activation of muscle spindles plays a crucial role in reflexive responses, such as the stretch reflex (myotatic reflex), which helps maintain muscle tone and joint stability. Additionally, they contribute to our sense of body position and movement awareness, known as kinesthesia.

A startle reaction is a natural, defensive response to an unexpected stimulus that is characterized by a sudden contraction of muscles, typically in the face, neck, and arms. It's a reflexive action that occurs involuntarily and is mediated by the brainstem. The startle reaction can be observed in many different species, including humans, and is thought to have evolved as a protective mechanism to help organisms respond quickly to potential threats. In addition to the muscle contraction, the startle response may also include other physiological changes such as an increase in heart rate and blood pressure.

A cough is a reflex action that helps to clear the airways of irritants, foreign particles, or excess mucus or phlegm. It is characterized by a sudden, forceful expulsion of air from the lungs through the mouth and nose. A cough can be acute (short-term) or chronic (long-term), and it can be accompanied by other symptoms such as chest pain, shortness of breath, or fever. Coughing can be caused by various factors, including respiratory infections, allergies, asthma, environmental pollutants, gastroesophageal reflux disease (GERD), and chronic lung diseases such as chronic obstructive pulmonary disease (COPD) and bronchitis. In some cases, a cough may be a symptom of a more serious underlying condition, such as heart failure or lung cancer.

Posture is the position or alignment of body parts supported by the muscles, especially the spine and head in relation to the vertebral column. It can be described as static (related to a stationary position) or dynamic (related to movement). Good posture involves training your body to stand, walk, sit, and lie in positions where the least strain is placed on supporting muscles and ligaments during movement or weight-bearing activities. Poor posture can lead to various health issues such as back pain, neck pain, headaches, and respiratory problems.

Denervation is a medical term that refers to the loss or removal of nerve supply to an organ or body part. This can occur as a result of surgical intervention, injury, or disease processes that damage the nerves leading to the affected area. The consequences of denervation depend on the specific organ or tissue involved, but generally, it can lead to changes in function, sensation, and muscle tone. For example, denervation of a skeletal muscle can cause weakness, atrophy, and altered reflexes. Similarly, denervation of an organ such as the heart can lead to abnormalities in heart rate and rhythm. In some cases, denervation may be intentional, such as during surgical procedures aimed at treating chronic pain or spasticity.

Reaction time, in the context of medicine and physiology, refers to the time period between the presentation of a stimulus and the subsequent initiation of a response. This complex process involves the central nervous system, particularly the brain, which perceives the stimulus, processes it, and then sends signals to the appropriate muscles or glands to react.

There are different types of reaction times, including simple reaction time (responding to a single, expected stimulus) and choice reaction time (choosing an appropriate response from multiple possibilities). These measures can be used in clinical settings to assess various aspects of neurological function, such as cognitive processing speed, motor control, and alertness.

However, it is important to note that reaction times can be influenced by several factors, including age, fatigue, attention, and the use of certain medications or substances.

In the context of medicine and healthcare, "movement" refers to the act or process of changing physical location or position. It involves the contraction and relaxation of muscles, which allows for the joints to move and the body to be in motion. Movement can also refer to the ability of a patient to move a specific body part or limb, which is assessed during physical examinations. Additionally, "movement" can describe the progression or spread of a disease within the body.

Peristalsis is an involuntary muscular movement that occurs in the digestive tract, including the esophagus, stomach, and intestines. It is characterized by alternate contraction and relaxation of the smooth muscles in the walls of these organs, which creates a wave-like motion that helps propel food, fluids, and waste through the digestive system.

The process of peristalsis begins with a narrowing or constriction of the muscle in one area of the digestive tract, followed by a relaxation of the muscle in the adjacent area. This creates a localized contraction that moves along the length of the organ, pushing its contents forward. The wave of contractions continues to move along the digestive tract until it reaches the anus, where waste is eliminated from the body.

Peristalsis plays a crucial role in maintaining proper digestion and absorption of nutrients, as well as in the elimination of waste products from the body. Disorders that affect peristalsis, such as gastrointestinal motility disorders, can lead to symptoms such as abdominal pain, bloating, constipation, or diarrhea.

A muscle is a soft tissue in our body that contracts to produce force and motion. It is composed mainly of specialized cells called muscle fibers, which are bound together by connective tissue. There are three types of muscles: skeletal (voluntary), smooth (involuntary), and cardiac. Skeletal muscles attach to bones and help in movement, while smooth muscles are found within the walls of organs and blood vessels, helping with functions like digestion and circulation. Cardiac muscle is the specific type that makes up the heart, allowing it to pump blood throughout the body.

Muscle rigidity is a term used to describe an increased resistance to passive movement or muscle tone that is present at rest, which cannot be overcome by the person. It is a common finding in various neurological conditions such as Parkinson's disease, stiff-person syndrome, and tetanus. In these conditions, muscle rigidity can result from hyperexcitability of the stretch reflex arc or abnormalities in the basal ganglia circuitry.

Muscle rigidity should be distinguished from spasticity, which is a velocity-dependent increase in muscle tone that occurs during voluntary movement or passive stretching. Spasticity is often seen in upper motor neuron lesions such as stroke or spinal cord injury.

It's important to note that the assessment of muscle rigidity requires a careful physical examination and may need to be evaluated in conjunction with other signs and symptoms to determine an underlying cause.

Bradycardia is a medical term that refers to an abnormally slow heart rate, typically defined as a resting heart rate of less than 60 beats per minute in adults. While some people, particularly well-trained athletes, may have a naturally low resting heart rate, bradycardia can also be a sign of an underlying health problem.

There are several potential causes of bradycardia, including:

* Damage to the heart's electrical conduction system, such as from heart disease or aging
* Certain medications, including beta blockers, calcium channel blockers, and digoxin
* Hypothyroidism (underactive thyroid gland)
* Sleep apnea
* Infection of the heart (endocarditis or myocarditis)
* Infiltrative diseases such as amyloidosis or sarcoidosis

Symptoms of bradycardia can vary depending on the severity and underlying cause. Some people with bradycardia may not experience any symptoms, while others may feel weak, fatigued, dizzy, or short of breath. In severe cases, bradycardia can lead to fainting, confusion, or even cardiac arrest.

Treatment for bradycardia depends on the underlying cause. If a medication is causing the slow heart rate, adjusting the dosage or switching to a different medication may help. In other cases, a pacemaker may be necessary to regulate the heart's rhythm. It is important to seek medical attention if you experience symptoms of bradycardia, as it can be a sign of a serious underlying condition.

The Peroneal nerve, also known as the common fibular nerve, is a branch of the sciatic nerve that supplies the muscles of the lower leg and provides sensation to the skin on the outer part of the lower leg and the top of the foot. It winds around the neck of the fibula (calf bone) and can be vulnerable to injury in this area, leading to symptoms such as weakness or numbness in the foot and leg.

Cordotomy is a surgical procedure that involves selectively cutting the spinothalamic tract, which carries pain and temperature signals from the body to the brain. This procedure is typically performed in the cervical (neck) region of the spinal cord and is used to treat chronic, severe pain that has not responded to other forms of treatment.

During a cordotomy, a neurosurgeon uses a specialized needle or electrode to locate and destroy the specific nerve fibers responsible for transmitting painful sensations from a particular part of the body. The procedure can be performed under local anesthesia with sedation or general anesthesia, depending on the patient's preferences and medical condition.

While cordotomy can provide significant pain relief in the short term, it is not a permanent solution, as the nerve fibers may eventually regenerate over time. Additionally, there are risks associated with the procedure, including weakness or numbness in the affected limbs, difficulty swallowing, and in rare cases, respiratory failure. Therefore, cordotomy is typically reserved for patients with severe pain who have exhausted other treatment options and have a limited life expectancy due to their underlying medical condition.

A hindlimb, also known as a posterior limb, is one of the pair of extremities that are located distally to the trunk in tetrapods (four-legged vertebrates) and include mammals, birds, reptiles, and amphibians. In humans and other primates, hindlimbs are equivalent to the lower limbs, which consist of the thigh, leg, foot, and toes.

The primary function of hindlimbs is locomotion, allowing animals to move from one place to another. However, they also play a role in other activities such as balance, support, and communication. In humans, the hindlimbs are responsible for weight-bearing, standing, walking, running, and jumping.

In medical terminology, the term "hindlimb" is not commonly used to describe human anatomy. Instead, healthcare professionals use terms like lower limbs or lower extremities to refer to the same region of the body. However, in comparative anatomy and veterinary medicine, the term hindlimb is still widely used to describe the corresponding structures in non-human animals.

The otolithic membrane is a part of the inner ear's vestibular system, which contributes to our sense of balance and spatial orientation. It is composed of a gelatinous material containing tiny calcium carbonate crystals called otoconia or otoliths. These crystals provide weight to the membrane, allowing it to detect linear acceleration and gravity-induced head movements.

There are two otolithic membranes in each inner ear, located within the utricle and saccule, two of the three main vestibular organs. The utricle is primarily responsible for detecting horizontal movement and head tilts, while the saccule senses vertical motion and linear acceleration.

Damage to the otolithic membrane can result in balance disorders, vertigo, or dizziness.

The solitary nucleus, also known as the nucleus solitarius, is a collection of neurons located in the medulla oblongata region of the brainstem. It plays a crucial role in the processing and integration of sensory information, particularly taste and visceral afferent fibers from internal organs. The solitary nucleus receives inputs from various cranial nerves, including the glossopharyngeal (cranial nerve IX) and vagus nerves (cranial nerve X), and is involved in reflex responses related to swallowing, vomiting, and cardiovascular regulation.

Neural inhibition is a process in the nervous system that decreases or prevents the activity of neurons (nerve cells) in order to regulate and control communication within the nervous system. It is a fundamental mechanism that allows for the balance of excitation and inhibition necessary for normal neural function. Inhibitory neurotransmitters, such as GABA (gamma-aminobutyric acid) and glycine, are released from the presynaptic neuron and bind to receptors on the postsynaptic neuron, reducing its likelihood of firing an action potential. This results in a decrease in neural activity and can have various effects depending on the specific neurons and brain regions involved. Neural inhibition is crucial for many functions including motor control, sensory processing, attention, memory, and emotional regulation.

In medical terms, the foot is the part of the lower limb that is distal to the leg and below the ankle, extending from the tarsus to the toes. It is primarily responsible for supporting body weight and facilitating movement through push-off during walking or running. The foot is a complex structure made up of 26 bones, 33 joints, and numerous muscles, tendons, ligaments, and nerves that work together to provide stability, balance, and flexibility. It can be divided into three main parts: the hindfoot, which contains the talus and calcaneus (heel) bones; the midfoot, which includes the navicular, cuboid, and cuneiform bones; and the forefoot, which consists of the metatarsals and phalanges that form the toes.

Head movements refer to the voluntary or involuntary motion of the head in various directions. These movements can occur in different planes, including flexion (moving the head forward), extension (moving the head backward), rotation (turning the head to the side), and lateral bending (leaning the head to one side).

Head movements can be a result of normal physiological processes, such as when nodding in agreement or shaking the head to indicate disagreement. They can also be caused by neurological conditions, such as abnormal head movements in patients with Parkinson's disease or cerebellar disorders. Additionally, head movements may occur in response to sensory stimuli, such as turning the head toward a sound.

In a medical context, an examination of head movements can provide important clues about a person's neurological function and help diagnose various conditions affecting the brain and nervous system.

Medical Definition of Respiration:

Respiration, in physiology, is the process by which an organism takes in oxygen and gives out carbon dioxide. It's also known as breathing. This process is essential for most forms of life because it provides the necessary oxygen for cellular respiration, where the cells convert biochemical energy from nutrients into adenosine triphosphate (ATP), and releases waste products, primarily carbon dioxide.

In humans and other mammals, respiration is a two-stage process:

1. Breathing (or external respiration): This involves the exchange of gases with the environment. Air enters the lungs through the mouth or nose, then passes through the pharynx, larynx, trachea, and bronchi, finally reaching the alveoli where the actual gas exchange occurs. Oxygen from the inhaled air diffuses into the blood, while carbon dioxide, a waste product of metabolism, diffuses from the blood into the alveoli to be exhaled.

2. Cellular respiration (or internal respiration): This is the process by which cells convert glucose and other nutrients into ATP, water, and carbon dioxide in the presence of oxygen. The carbon dioxide produced during this process then diffuses out of the cells and into the bloodstream to be exhaled during breathing.

In summary, respiration is a vital physiological function that enables organisms to obtain the necessary oxygen for cellular metabolism while eliminating waste products like carbon dioxide.

Efferent pathways refer to the neural connections that carry signals from the central nervous system (CNS), which includes the brain and spinal cord, to the peripheral effectors such as muscles and glands. These pathways are responsible for the initiation and control of motor responses, as well as regulating various autonomic functions.

Efferent pathways can be divided into two main types:

1. Somatic efferent pathways: These pathways carry signals from the CNS to the skeletal muscles, enabling voluntary movements and postural control. The final common pathway for somatic motor innervation is the alpha-motor neuron, which synapses directly onto skeletal muscle fibers.
2. Autonomic efferent pathways: These pathways regulate the function of internal organs, smooth muscles, and glands. They are further divided into two subtypes: sympathetic and parasympathetic. The sympathetic system is responsible for the 'fight or flight' response, while the parasympathetic system promotes rest and digestion. Both systems use a two-neuron chain to transmit signals from the CNS to the effector organs. The preganglionic neuron has its cell body in the CNS and synapses with the postganglionic neuron in an autonomic ganglion located near the effector organ. The postganglionic neuron then innervates the target organ or tissue.

In summary, efferent pathways are the neural connections that carry signals from the CNS to peripheral effectors, enabling motor responses and regulating various autonomic functions. They can be divided into somatic and autonomic efferent pathways, with further subdivisions within the autonomic system.

In the context of medicine, particularly in anatomy and physiology, "rotation" refers to the movement of a body part around its own axis or the long axis of another structure. This type of motion is three-dimensional and can occur in various planes. A common example of rotation is the movement of the forearm bones (radius and ulna) around each other during pronation and supination, which allows the hand to be turned palm up or down. Another example is the rotation of the head during mastication (chewing), where the mandible moves in a circular motion around the temporomandibular joint.

Eye movements, also known as ocular motility, refer to the voluntary or involuntary motion of the eyes that allows for visual exploration of our environment. There are several types of eye movements, including:

1. Saccades: rapid, ballistic movements that quickly shift the gaze from one point to another.
2. Pursuits: smooth, slow movements that allow the eyes to follow a moving object.
3. Vergences: coordinated movements of both eyes in opposite directions, usually in response to a three-dimensional stimulus.
4. Vestibulo-ocular reflex (VOR): automatic eye movements that help stabilize the gaze during head movement.
5. Optokinetic nystagmus (OKN): rhythmic eye movements that occur in response to large moving visual patterns, such as when looking out of a moving vehicle.

Abnormalities in eye movements can indicate neurological or ophthalmological disorders and are often assessed during clinical examinations.

Physiologic nystagmus is a type of normal, involuntary eye movement that occurs in certain situations. It is characterized by rhythmical to-and-fro movements of the eyes, which can be horizontal, vertical, or rotatory. The most common form of physiologic nystagmus is called "optokinetic nystagmus," which occurs when a person looks at a moving pattern, such as stripes on a rotating drum or scenery passing by a car window.

Optokinetic nystagmus helps to stabilize the image of the environment on the retina and allows the brain to perceive motion accurately. Another form of physiologic nystagmus is "pursuit nystagmus," which occurs when the eyes attempt to follow a slowly moving target. In this case, the eyes may overshoot the target and then make a corrective movement in the opposite direction.

Physiologic nystagmus is different from pathological nystagmus, which can be caused by various medical conditions such as brain damage, inner ear disorders, or medications that affect the nervous system. Pathological nystagmus may indicate a serious underlying condition and should be evaluated by a healthcare professional.

Proprioception is the unconscious perception of movement and spatial orientation arising from stimuli within the body itself. It is sometimes described as the "sixth sense" and it's all about knowing where your body parts are, how they are moving, and the effort being used to move them. This information is crucial for motor control, balance, and coordination.

The proprioceptive system includes sensory receptors called proprioreceptors located in muscles, tendons, and joints that send messages to the brain through nerves regarding body position and movement. These messages are then integrated with information from other senses, such as vision and vestibular sense (related to balance), to create a complete understanding of the body's position and motion in space.

Deficits in proprioception can lead to problems with coordination, balance, and fine motor skills.

The medulla oblongata is a part of the brainstem that is located in the posterior portion of the brainstem and continues with the spinal cord. It plays a vital role in controlling several critical bodily functions, such as breathing, heart rate, and blood pressure. The medulla oblongata also contains nerve pathways that transmit sensory information from the body to the brain and motor commands from the brain to the muscles. Additionally, it is responsible for reflexes such as vomiting, swallowing, coughing, and sneezing.

The urinary bladder is a muscular, hollow organ in the pelvis that stores urine before it is released from the body. It expands as it fills with urine and contracts when emptying. The typical adult bladder can hold between 400 to 600 milliliters of urine for about 2-5 hours before the urge to urinate occurs. The wall of the bladder contains several layers, including a mucous membrane, a layer of smooth muscle (detrusor muscle), and an outer fibrous adventitia. The muscles of the bladder neck and urethra remain contracted to prevent leakage of urine during filling, and they relax during voiding to allow the urine to flow out through the urethra.

Deglutition is the medical term for swallowing. It refers to the process by which food or liquid is transferred from the mouth to the stomach through a series of coordinated muscle movements and neural responses. The deglutition process involves several stages, including oral preparatory, oral transit, pharyngeal, and esophageal phases, each of which plays a critical role in ensuring safe and efficient swallowing.

Dysphagia is the medical term for difficulty with swallowing, which can result from various underlying conditions such as neurological disorders, structural abnormalities, or muscular weakness. Proper evaluation and management of deglutition disorders are essential to prevent complications such as aspiration pneumonia, malnutrition, and dehydration.

In the context of medicine and physiology, vibration refers to the mechanical oscillation of a physical body or substance with a periodic back-and-forth motion around an equilibrium point. This motion can be produced by external forces or internal processes within the body.

Vibration is often measured in terms of frequency (the number of cycles per second) and amplitude (the maximum displacement from the equilibrium position). In clinical settings, vibration perception tests are used to assess peripheral nerve function and diagnose conditions such as neuropathy.

Prolonged exposure to whole-body vibration or hand-transmitted vibration in certain occupational settings can also have adverse health effects, including hearing loss, musculoskeletal disorders, and vascular damage.

Pulmonary stretch receptors are nerve endings (receptors) located in the smooth muscle of the airways, specifically within the bronchi and bronchioles of the lungs. They are also known as irritant receptors or slowly adapting receptors. These receptors respond to mechanical deformation caused by lung inflation during breathing. When the lungs stretch, these receptors send signals to the brain via the vagus nerve, which helps regulate breathing patterns and depth. This reflex is known as the Hering-Breuer reflex, which can inhibit inspiration and promote expiration, preventing overinflation of the lungs and helping maintain lung volume within normal ranges.

Nociceptors are specialized peripheral sensory neurons that detect and transmit signals indicating potentially harmful stimuli in the form of pain. They are activated by various noxious stimuli such as extreme temperatures, intense pressure, or chemical irritants. Once activated, nociceptors transmit these signals to the central nervous system (spinal cord and brain) where they are interpreted as painful sensations, leading to protective responses like withdrawing from the harmful stimulus or seeking medical attention. Nociceptors play a crucial role in our perception of pain and help protect the body from further harm.

The masseter muscle is a strong chewing muscle in the jaw. It is a broad, thick, quadrilateral muscle that extends from the zygomatic arch (cheekbone) to the lower jaw (mandible). The masseter muscle has two distinct parts: the superficial part and the deep part.

The superficial part of the masseter muscle originates from the lower border of the zygomatic process of the maxilla and the anterior two-thirds of the inferior border of the zygomatic arch. The fibers of this part run almost vertically downward to insert on the lateral surface of the ramus of the mandible and the coronoid process.

The deep part of the masseter muscle originates from the deep surface of the zygomatic arch and inserts on the medial surface of the ramus of the mandible, blending with the temporalis tendon.

The primary function of the masseter muscle is to elevate the mandible, helping to close the mouth and clench the teeth together during mastication (chewing). It also plays a role in stabilizing the jaw during biting and speaking. The masseter muscle is one of the most powerful muscles in the human body relative to its size.

The vestibular nerve, also known as the vestibulocochlear nerve or cranial nerve VIII, is a pair of nerves that transmit sensory information from the balance-sensing structures in the inner ear (the utricle, saccule, and semicircular canals) to the brain. This information helps the brain maintain balance and orientation of the head in space. The vestibular nerve also plays a role in hearing by transmitting sound signals from the cochlea to the brain.

Anesthesia is a medical term that refers to the loss of sensation or awareness, usually induced by the administration of various drugs. It is commonly used during surgical procedures to prevent pain and discomfort. There are several types of anesthesia, including:

1. General anesthesia: This type of anesthesia causes a complete loss of consciousness and is typically used for major surgeries.
2. Regional anesthesia: This type of anesthesia numbs a specific area of the body, such as an arm or leg, while the patient remains conscious.
3. Local anesthesia: This type of anesthesia numbs a small area of the body, such as a cut or wound, and is typically used for minor procedures.

Anesthesia can be administered through various routes, including injection, inhalation, or topical application. The choice of anesthesia depends on several factors, including the type and duration of the procedure, the patient's medical history, and their overall health. Anesthesiologists are medical professionals who specialize in administering anesthesia and monitoring patients during surgical procedures to ensure their safety and comfort.

A spasm is a sudden, involuntary contraction or tightening of a muscle, group of muscles, or a hollow organ such as the ureter or bronchi. Spasms can occur as a result of various factors including muscle fatigue, injury, irritation, or abnormal nerve activity. They can cause pain and discomfort, and in some cases, interfere with normal bodily functions. For example, a spasm in the bronchi can cause difficulty breathing, while a spasm in the ureter can cause severe pain and may lead to a kidney stone blockage. The treatment for spasms depends on the underlying cause and may include medication, physical therapy, or lifestyle changes.

The anal canal is the terminal portion of the digestive tract, located between the rectum and the anus. It is a short tube-like structure that is about 1 to 1.5 inches long in adults. The main function of the anal canal is to provide a seal for the elimination of feces from the body while also preventing the leakage of intestinal contents.

The inner lining of the anal canal is called the mucosa, which is kept moist by the production of mucus. The walls of the anal canal contain specialized muscles that help control the passage of stool during bowel movements. These muscles include the internal and external sphincters, which work together to maintain continence and allow for the voluntary release of feces.

The anal canal is an important part of the digestive system and plays a critical role in maintaining bowel function and overall health.

The brainstem is the lower part of the brain that connects to the spinal cord. It consists of the midbrain, pons, and medulla oblongata. The brainstem controls many vital functions such as heart rate, breathing, and blood pressure. It also serves as a relay center for sensory and motor information between the cerebral cortex and the rest of the body. Additionally, several cranial nerves originate from the brainstem, including those that control eye movements, facial movements, and hearing.

In medical terms, pressure is defined as the force applied per unit area on an object or body surface. It is often measured in millimeters of mercury (mmHg) in clinical settings. For example, blood pressure is the force exerted by circulating blood on the walls of the arteries and is recorded as two numbers: systolic pressure (when the heart beats and pushes blood out) and diastolic pressure (when the heart rests between beats).

Pressure can also refer to the pressure exerted on a wound or incision to help control bleeding, or the pressure inside the skull or spinal canal. High or low pressure in different body systems can indicate various medical conditions and require appropriate treatment.

The semicircular canals are part of the vestibular system in the inner ear that contributes to the sense of balance and spatial orientation. They are composed of three fluid-filled tubes, each located in a different plane (anterior, posterior, and horizontal) and arranged at approximately right angles to each other. The semicircular canals detect rotational movements of the head, enabling us to maintain our equilibrium during movement.

When the head moves, the fluid within the semicircular canals moves in response to that motion. At the end of each canal is a structure called the ampulla, which contains hair cells with hair-like projections (stereocilia) embedded in a gelatinous substance. As the fluid moves, it bends the stereocilia, stimulating the hair cells and sending signals to the brain via the vestibular nerve. The brain then interprets these signals to determine the direction and speed of head movement, allowing us to maintain our balance and orientation in space.

Sprague-Dawley rats are a strain of albino laboratory rats that are widely used in scientific research. They were first developed by researchers H.H. Sprague and R.C. Dawley in the early 20th century, and have since become one of the most commonly used rat strains in biomedical research due to their relatively large size, ease of handling, and consistent genetic background.

Sprague-Dawley rats are outbred, which means that they are genetically diverse and do not suffer from the same limitations as inbred strains, which can have reduced fertility and increased susceptibility to certain diseases. They are also characterized by their docile nature and low levels of aggression, making them easier to handle and study than some other rat strains.

These rats are used in a wide variety of research areas, including toxicology, pharmacology, nutrition, cancer, and behavioral studies. Because they are genetically diverse, Sprague-Dawley rats can be used to model a range of human diseases and conditions, making them an important tool in the development of new drugs and therapies.

Habituation, psychophysiologic, refers to the decrease in autonomic nervous system response to repeated exposure to a stimulus. It is a form of learning that occurs when an individual is exposed to a stimulus repeatedly over time, leading to a reduced reaction or no reaction at all. This process involves the decreased responsiveness of both the sympathetic and parasympathetic branches of the autonomic nervous system.

Examples of psychophysiologic habituation include the decreased heart rate and skin conductance response that occurs with repeated exposure to a startling stimulus, such as a loud noise. This form of habituation is thought to be an adaptive mechanism that allows individuals to respond appropriately to novel or important stimuli while reducing the response to non-significant or irrelevant stimuli.

It's worth noting that habituation can also occur in other systems and contexts, such as sensory habituation (decreased response to repeated sensory stimulation) or cognitive habituation (reduced attention or memory for repeated exposure to a stimulus). However, the term "psychophysiologic habituation" specifically refers to the decreased autonomic nervous system response that occurs with repeated exposure to a stimulus.

Spinal cord injuries (SCI) refer to damage to the spinal cord that results in a loss of function, such as mobility or feeling. This injury can be caused by direct trauma to the spine or by indirect damage resulting from disease or degeneration of surrounding bones, tissues, or blood vessels. The location and severity of the injury on the spinal cord will determine which parts of the body are affected and to what extent.

The effects of SCI can range from mild sensory changes to severe paralysis, including loss of motor function, autonomic dysfunction, and possible changes in sensation, strength, and reflexes below the level of injury. These injuries are typically classified as complete or incomplete, depending on whether there is any remaining function below the level of injury.

Immediate medical attention is crucial for spinal cord injuries to prevent further damage and improve the chances of recovery. Treatment usually involves immobilization of the spine, medications to reduce swelling and pressure, surgery to stabilize the spine, and rehabilitation to help regain lost function. Despite advances in treatment, SCI can have a significant impact on a person's quality of life and ability to perform daily activities.

Eyelids are the thin folds of skin that cover and protect the front surface (cornea) of the eye when closed. They are composed of several layers, including the skin, muscle, connective tissue, and a mucous membrane called the conjunctiva. The upper and lower eyelids meet at the outer corner of the eye (lateral canthus) and the inner corner of the eye (medial canthus).

The main function of the eyelids is to protect the eye from foreign particles, light, and trauma. They also help to distribute tears evenly over the surface of the eye through blinking, which helps to keep the eye moist and healthy. Additionally, the eyelids play a role in facial expressions and non-verbal communication.

Central muscle relaxants are a class of pharmaceutical agents that act on the central nervous system (CNS) to reduce skeletal muscle tone and spasticity. These medications do not directly act on the muscles themselves but rather work by altering the messages sent between the brain and the muscles, thereby reducing excessive muscle contraction and promoting relaxation.

Central muscle relaxants are often prescribed for the management of various neuromuscular disorders, such as multiple sclerosis, spinal cord injuries, cerebral palsy, and stroke-induced spasticity. They may also be used to treat acute musculoskeletal conditions like strains, sprains, or other muscle injuries.

Examples of central muscle relaxants include baclofen, tizanidine, cyclobenzaprine, methocarbamol, and diazepam. It is important to note that these medications can have side effects such as drowsiness, dizziness, and impaired cognitive function, so they should be used with caution and under the guidance of a healthcare professional.

The urethra is the tube that carries urine from the bladder out of the body. In males, it also serves as the conduit for semen during ejaculation. The male urethra is longer than the female urethra and is divided into sections: the prostatic, membranous, and spongy (or penile) urethra. The female urethra extends from the bladder to the external urethral orifice, which is located just above the vaginal opening.

Chloralose is not a medical term commonly used in modern medicine. However, historically, it is a chemical compound that has been used in research and veterinary medicine as an sedative and hypnotic agent. It is a combination of chloral hydrate and sodium pentobarbital.

Chloralose has been used in research to study the effects of sedation on various physiological processes, such as respiration and circulation. In veterinary medicine, it has been used as an anesthetic for small animals during surgical procedures. However, due to its potential for serious side effects, including respiratory depression and cardiac arrest, chloralose is not commonly used in clinical practice today.

I believe there might be a misunderstanding in your question. "Dogs" is not a medical term or condition. It is the common name for a domesticated carnivore of the family Canidae, specifically the genus Canis, which includes wolves, foxes, and other extant and extinct species of mammals. Dogs are often kept as pets and companions, and they have been bred in a wide variety of forms and sizes for different purposes, such as hunting, herding, guarding, assisting police and military forces, and providing companionship and emotional support.

If you meant to ask about a specific medical condition or term related to dogs, please provide more context so I can give you an accurate answer.

Evoked potentials (EPs) are medical tests that measure the electrical activity in the brain or spinal cord in response to specific sensory stimuli, such as sight, sound, or touch. These tests are often used to help diagnose and monitor conditions that affect the nervous system, such as multiple sclerosis, brainstem tumors, and spinal cord injuries.

There are several types of EPs, including:

1. Visual Evoked Potentials (VEPs): These are used to assess the function of the visual pathway from the eyes to the back of the brain. A patient is typically asked to look at a patterned image or flashing light while electrodes placed on the scalp record the electrical responses.
2. Brainstem Auditory Evoked Potentials (BAEPs): These are used to evaluate the function of the auditory nerve and brainstem. Clicking sounds are presented to one or both ears, and electrodes placed on the scalp measure the response.
3. Somatosensory Evoked Potentials (SSEPs): These are used to assess the function of the peripheral nerves and spinal cord. Small electrical shocks are applied to a nerve at the wrist or ankle, and electrodes placed on the scalp record the response as it travels up the spinal cord to the brain.
4. Motor Evoked Potentials (MEPs): These are used to assess the function of the motor pathways in the brain and spinal cord. A magnetic or electrical stimulus is applied to the brain or spinal cord, and electrodes placed on a muscle measure the response as it travels down the motor pathway.

EPs can help identify abnormalities in the nervous system that may not be apparent through other diagnostic tests, such as imaging studies or clinical examinations. They are generally safe, non-invasive procedures with few risks or side effects.

Atropine is an anticholinergic drug that blocks the action of the neurotransmitter acetylcholine in the central and peripheral nervous system. It is derived from the belladonna alkaloids, which are found in plants such as deadly nightshade (Atropa belladonna), Jimson weed (Datura stramonium), and Duboisia spp.

In clinical medicine, atropine is used to reduce secretions, increase heart rate, and dilate the pupils. It is often used before surgery to dry up secretions in the mouth, throat, and lungs, and to reduce salivation during the procedure. Atropine is also used to treat certain types of nerve agent and pesticide poisoning, as well as to manage bradycardia (slow heart rate) and hypotension (low blood pressure) caused by beta-blockers or calcium channel blockers.

Atropine can have several side effects, including dry mouth, blurred vision, dizziness, confusion, and difficulty urinating. In high doses, it can cause delirium, hallucinations, and seizures. Atropine should be used with caution in patients with glaucoma, prostatic hypertrophy, or other conditions that may be exacerbated by its anticholinergic effects.

Neural conduction is the process by which electrical signals, known as action potentials, are transmitted along the axon of a neuron (nerve cell) to transmit information between different parts of the nervous system. This electrical impulse is generated by the movement of ions across the neuronal membrane, and it propagates down the length of the axon until it reaches the synapse, where it can then stimulate the release of neurotransmitters to communicate with other neurons or target cells. The speed of neural conduction can vary depending on factors such as the diameter of the axon, the presence of myelin sheaths (which act as insulation and allow for faster conduction), and the temperature of the environment.

The larynx, also known as the voice box, is a complex structure in the neck that plays a crucial role in protection of the lower respiratory tract and in phonation. It is composed of cartilaginous, muscular, and soft tissue structures. The primary functions of the larynx include:

1. Airway protection: During swallowing, the larynx moves upward and forward to close the opening of the trachea (the glottis) and prevent food or liquids from entering the lungs. This action is known as the swallowing reflex.
2. Phonation: The vocal cords within the larynx vibrate when air passes through them, producing sound that forms the basis of human speech and voice production.
3. Respiration: The larynx serves as a conduit for airflow between the upper and lower respiratory tracts during breathing.

The larynx is located at the level of the C3-C6 vertebrae in the neck, just above the trachea. It consists of several important structures:

1. Cartilages: The laryngeal cartilages include the thyroid, cricoid, and arytenoid cartilages, as well as the corniculate and cuneiform cartilages. These form a framework for the larynx and provide attachment points for various muscles.
2. Vocal cords: The vocal cords are thin bands of mucous membrane that stretch across the glottis (the opening between the arytenoid cartilages). They vibrate when air passes through them, producing sound.
3. Muscles: There are several intrinsic and extrinsic muscles associated with the larynx. The intrinsic muscles control the tension and position of the vocal cords, while the extrinsic muscles adjust the position and movement of the larynx within the neck.
4. Nerves: The larynx is innervated by both sensory and motor nerves. The recurrent laryngeal nerve provides motor innervation to all intrinsic laryngeal muscles, except for one muscle called the cricothyroid, which is innervated by the external branch of the superior laryngeal nerve. Sensory innervation is provided by the internal branch of the superior laryngeal nerve and the recurrent laryngeal nerve.

The larynx plays a crucial role in several essential functions, including breathing, speaking, and protecting the airway during swallowing. Dysfunction or damage to the larynx can result in various symptoms, such as hoarseness, difficulty swallowing, shortness of breath, or stridor (a high-pitched sound heard during inspiration).

Masticatory muscles are a group of skeletal muscles responsible for the mastication (chewing) process in humans and other animals. They include:

1. Masseter muscle: This is the primary muscle for chewing and is located on the sides of the face, running from the lower jawbone (mandible) to the cheekbone (zygomatic arch). It helps close the mouth and elevate the mandible during chewing.

2. Temporalis muscle: This muscle is situated in the temporal region of the skull, covering the temple area. It assists in closing the jaw, retracting the mandible, and moving it sideways during chewing.

3. Medial pterygoid muscle: Located deep within the cheek, near the angle of the lower jaw, this muscle helps move the mandible forward and grind food during chewing. It also contributes to closing the mouth.

4. Lateral pterygoid muscle: Found inside the ramus (the vertical part) of the mandible, this muscle has two heads - superior and inferior. The superior head helps open the mouth by pulling the temporomandibular joint (TMJ) downwards, while the inferior head assists in moving the mandible sideways during chewing.

These muscles work together to enable efficient chewing and food breakdown, preparing it for swallowing and digestion.

An action potential is a brief electrical signal that travels along the membrane of a nerve cell (neuron) or muscle cell. It is initiated by a rapid, localized change in the permeability of the cell membrane to specific ions, such as sodium and potassium, resulting in a rapid influx of sodium ions and a subsequent efflux of potassium ions. This ion movement causes a brief reversal of the electrical potential across the membrane, which is known as depolarization. The action potential then propagates along the cell membrane as a wave, allowing the electrical signal to be transmitted over long distances within the body. Action potentials play a crucial role in the communication and functioning of the nervous system and muscle tissue.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

In medical terms, the leg refers to the lower portion of the human body that extends from the knee down to the foot. It includes the thigh (femur), lower leg (tibia and fibula), foot, and ankle. The leg is primarily responsible for supporting the body's weight and enabling movements such as standing, walking, running, and jumping.

The leg contains several important structures, including bones, muscles, tendons, ligaments, blood vessels, nerves, and joints. These structures work together to provide stability, support, and mobility to the lower extremity. Common medical conditions that can affect the leg include fractures, sprains, strains, infections, peripheral artery disease, and neurological disorders.

Neural pathways, also known as nerve tracts or fasciculi, refer to the highly organized and specialized routes through which nerve impulses travel within the nervous system. These pathways are formed by groups of neurons (nerve cells) that are connected in a series, creating a continuous communication network for electrical signals to transmit information between different regions of the brain, spinal cord, and peripheral nerves.

Neural pathways can be classified into two main types: sensory (afferent) and motor (efferent). Sensory neural pathways carry sensory information from various receptors in the body (such as those for touch, temperature, pain, and vision) to the brain for processing. Motor neural pathways, on the other hand, transmit signals from the brain to the muscles and glands, controlling movements and other effector functions.

The formation of these neural pathways is crucial for normal nervous system function, as it enables efficient communication between different parts of the body and allows for complex behaviors, cognitive processes, and adaptive responses to internal and external stimuli.

Medical definition: "Milk ejection," also known as the "let-down reflex," is the release of milk from the alveoli (milk-producing sacs) of the breast during breastfeeding or pumping. It occurs when the hormone oxytocin is released into the bloodstream, causing the smooth muscles surrounding the alveoli to contract and push out the milk. This reflex is an essential part of lactation and helps ensure that the baby receives enough milk during feeding. The milk ejection can be triggered by various stimuli such as suckling, thinking about or hearing the baby, or physical touch.

In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.

The cardiovascular system, also known as the circulatory system, is a biological system responsible for pumping and transporting blood throughout the body in animals and humans. It consists of the heart, blood vessels (comprising arteries, veins, and capillaries), and blood. The main function of this system is to transport oxygen, nutrients, hormones, and cellular waste products throughout the body to maintain homeostasis and support organ function.

The heart acts as a muscular pump that contracts and relaxes to circulate blood. It has four chambers: two atria on the top and two ventricles on the bottom. The right side of the heart receives deoxygenated blood from the body, pumps it through the lungs for oxygenation, and then sends it back to the left side of the heart. The left side of the heart then pumps the oxygenated blood through the aorta and into the systemic circulation, reaching all parts of the body via a network of arteries and capillaries. Deoxygenated blood is collected by veins and returned to the right atrium, completing the cycle.

The cardiovascular system plays a crucial role in regulating temperature, pH balance, and fluid balance throughout the body. It also contributes to the immune response and wound healing processes. Dysfunctions or diseases of the cardiovascular system can lead to severe health complications, such as hypertension, coronary artery disease, heart failure, stroke, and peripheral artery disease.

A pupil, in medical terms, refers to the circular opening in the center of the iris (the colored part of the eye) that allows light to enter and reach the retina. The size of the pupil can change involuntarily in response to light intensity and emotional state, as well as voluntarily through certain eye exercises or with the use of eye drops. Pupillary reactions are important in clinical examinations as they can provide valuable information about the nervous system's functioning, particularly the brainstem and cranial nerves II and III.

In medical terms, the jaw is referred to as the mandible (in humans and some other animals), which is the lower part of the face that holds the lower teeth in place. It's a large, horseshoe-shaped bone that forms the lower jaw and serves as a attachment point for several muscles that are involved in chewing and moving the lower jaw.

In addition to the mandible, the upper jaw is composed of two bones known as the maxillae, which fuse together at the midline of the face to form the upper jaw. The upper jaw holds the upper teeth in place and forms the roof of the mouth, as well as a portion of the eye sockets and nasal cavity.

Together, the mandible and maxillae allow for various functions such as speaking, eating, and breathing.

The vestibular nuclei are clusters of neurons located in the brainstem that receive and process information from the vestibular system, which is responsible for maintaining balance and spatial orientation. The vestibular nuclei help to coordinate movements of the eyes, head, and body in response to changes in position or movement. They also play a role in reflexes that help to maintain posture and stabilize vision during head movement. There are four main vestibular nuclei: the medial, lateral, superior, and inferior vestibular nuclei.

Nerve fibers are specialized structures that constitute the long, slender processes (axons) of neurons (nerve cells). They are responsible for conducting electrical impulses, known as action potentials, away from the cell body and transmitting them to other neurons or effector organs such as muscles and glands. Nerve fibers are often surrounded by supportive cells called glial cells and are grouped together to form nerve bundles or nerves. These fibers can be myelinated (covered with a fatty insulating sheath called myelin) or unmyelinated, which influences the speed of impulse transmission.

The Autonomic Nervous System (ANS) is a part of the peripheral nervous system that operates largely below the level of consciousness and controls visceral functions. It is divided into two main subdivisions: the sympathetic and parasympathetic nervous systems, which generally have opposing effects and maintain homeostasis in the body.

The Sympathetic Nervous System (SNS) prepares the body for stressful or emergency situations, often referred to as the "fight or flight" response. It increases heart rate, blood pressure, respiratory rate, and metabolic rate, while also decreasing digestive activity. This response helps the body respond quickly to perceived threats.

The Parasympathetic Nervous System (PNS), on the other hand, promotes the "rest and digest" state, allowing the body to conserve energy and restore itself after the stress response has subsided. It decreases heart rate, blood pressure, and respiratory rate, while increasing digestive activity and promoting relaxation.

These two systems work together to maintain balance in the body by adjusting various functions based on internal and external demands. Disorders of the Autonomic Nervous System can lead to a variety of symptoms, such as orthostatic hypotension, gastroparesis, and cardiac arrhythmias, among others.

"Skin physiological phenomena" is not a standard medical term with a specific definition. However, I can provide some information about the general concepts that might be encompassed by this term.

Physiological phenomena refer to the functions and processes that occur in living organisms. When it comes to the skin, there are many different physiological phenomena that take place, including:

1. Barrier function: The skin acts as a barrier to protect the body from external elements such as bacteria, viruses, chemicals, and UV radiation.
2. Temperature regulation: The skin helps regulate body temperature through sweat production and blood flow.
3. Sensation: The skin contains nerve endings that allow us to feel touch, pressure, pain, and temperature.
4. Vitamin D synthesis: The skin can produce vitamin D when exposed to sunlight.
5. Moisture regulation: The skin helps maintain the body's moisture balance by producing sweat and preventing water loss.
6. Immunological function: The skin plays a role in the immune system by providing a physical barrier and containing immune cells that help fight off infections.
7. Excretion: The skin eliminates waste products through sweat.
8. Wound healing: The skin has the ability to repair itself after injury, through a complex process involving inflammation, tissue regeneration, and remodeling.

Therefore, "skin physiological phenomena" could refer to any or all of these functions and processes that take place in the skin.

Locomotion, in a medical context, refers to the ability to move independently and change location. It involves the coordinated movement of the muscles, bones, and nervous system that enables an individual to move from one place to another. This can include walking, running, jumping, or using assistive devices such as wheelchairs or crutches. Locomotion is a fundamental aspect of human mobility and is often assessed in medical evaluations to determine overall health and functioning.

The ankle, also known as the talocrural region, is the joint between the leg and the foot. It is a synovial hinge joint that allows for dorsiflexion and plantarflexion movements. The ankle is composed of three bones: the tibia and fibula of the lower leg, and the talus of the foot. The bottom portion of the tibia and fibula, called the malleoli, form a mortise that surrounds and articulates with the talus.

The ankle joint is strengthened by several ligaments, including the medial (deltoid) ligament and lateral ligament complex. The ankle also contains important nerves and blood vessels that provide sensation and circulation to the foot.

Damage to the ankle joint, such as sprains or fractures, can result in pain, swelling, and difficulty walking. Proper care and rehabilitation are essential for maintaining the health and function of the ankle joint.

Respiratory physiological phenomena refer to the various mechanical, chemical, and biological processes and functions that occur in the respiratory system during breathing and gas exchange. These phenomena include:

1. Ventilation: The movement of air into and out of the lungs, which is achieved through the contraction and relaxation of the diaphragm and intercostal muscles.
2. Gas Exchange: The diffusion of oxygen (O2) from the alveoli into the bloodstream and carbon dioxide (CO2) from the bloodstream into the alveoli.
3. Respiratory Mechanics: The physical properties and forces that affect the movement of air in and out of the lungs, such as lung compliance, airway resistance, and chest wall elasticity.
4. Control of Breathing: The regulation of ventilation by the central nervous system through the integration of sensory information from chemoreceptors and mechanoreceptors in the respiratory system.
5. Acid-Base Balance: The maintenance of a stable pH level in the blood through the regulation of CO2 elimination and bicarbonate balance by the respiratory and renal systems.
6. Oxygen Transport: The binding of O2 to hemoglobin in the red blood cells and its delivery to the tissues for metabolic processes.
7. Defense Mechanisms: The various protective mechanisms that prevent the entry and colonization of pathogens and foreign particles into the respiratory system, such as mucociliary clearance, cough reflex, and immune responses.

The vasomotor system is a part of the autonomic nervous system that controls the diameter of blood vessels, particularly the smooth muscle in the walls of arterioles and precapillary sphincters. It regulates blood flow to different parts of the body by constricting or dilating these vessels. The vasomotor center located in the medulla oblongata of the brainstem controls the system, receiving input from various sensory receptors and modulating the sympathetic and parasympathetic nervous systems' activity. Vasoconstriction decreases blood flow, while vasodilation increases it.

The ankle joint, also known as the talocrural joint, is the articulation between the bones of the lower leg (tibia and fibula) and the talus bone in the foot. It is a synovial hinge joint that allows for dorsiflexion and plantarflexion movements, which are essential for walking, running, and jumping. The ankle joint is reinforced by strong ligaments on both sides to provide stability during these movements.

The autonomic nervous system (ANS) is a component of the peripheral nervous system that regulates involuntary physiological functions, such as heart rate, digestion, respiratory rate, pupillary response, urination, and sexual arousal. The autonomic pathways refer to the neural connections and signaling processes that allow the ANS to carry out these functions.

The autonomic pathways consist of two main subdivisions: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS). These systems have opposing effects on many organs, with the SNS generally stimulating activity and the PNS inhibiting it. The enteric nervous system, which controls gut function, is sometimes considered a third subdivision of the ANS.

The sympathetic pathway originates in the thoracic and lumbar regions of the spinal cord, with preganglionic neurons synapsing on postganglionic neurons in paravertebral ganglia or prevertebral ganglia. The parasympathetic pathway originates in the brainstem (cranial nerves III, VII, IX, and X) and the sacral region of the spinal cord (S2-S4), with preganglionic neurons synapsing on postganglionic neurons near or within the target organ.

Acetylcholine is the primary neurotransmitter used in both the sympathetic and parasympathetic pathways, although norepinephrine (noradrenaline) is also released by some postganglionic sympathetic neurons. The specific pattern of neural activation and inhibition within the autonomic pathways helps maintain homeostasis and allows for adaptive responses to changes in the internal and external environment.

In medical terms, the arm refers to the upper limb of the human body, extending from the shoulder to the wrist. It is composed of three major bones: the humerus in the upper arm, and the radius and ulna in the lower arm. The arm contains several joints, including the shoulder joint, elbow joint, and wrist joint, which allow for a wide range of motion. The arm also contains muscles, blood vessels, nerves, and other soft tissues that are essential for normal function.

The trigeminocardiac reflex (TCR) is a rare but well-documented phenomenon characterized by the sudden onset of various cardiovascular responses, such as bradycardia, asystole, or hypotension, following stimulation of any of the branches of the trigeminal nerve. The afferent limb of this reflex arc involves the sensory fibers of the trigeminal nerve, while the efferent limb consists of parasympathetic fibers originating from the vagus nerve and sympathetic fibers from the spinal cord.

TCR can be elicited by various surgical and non-surgical procedures, such as facial or dental manipulations, endonasal surgeries, or even spontaneously during migraine attacks. The clinical significance of TCR depends on the severity and duration of the cardiovascular response. In some cases, it may lead to severe hemodynamic instability, requiring prompt intervention, such as administering atropine or other medications to counteract the reflex.

Healthcare professionals should be aware of this reflex and its potential consequences, particularly in patients undergoing procedures involving the trigeminal nerve. Monitoring cardiovascular parameters during these procedures can help detect and manage TCR promptly, reducing the risk of adverse outcomes.

The pharyngeal muscles, also known as the musculature of the pharynx, are a group of skeletal muscles that make up the walls of the pharynx, which is the part of the throat located just above the esophagus and behind the nasal and oral cavities. These muscles play a crucial role in several vital functions, including:

1. Swallowing (deglutition): The pharyngeal muscles contract in a coordinated sequence to propel food or liquids from the mouth through the pharynx and into the esophagus during swallowing.
2. Speech: The contraction and relaxation of these muscles help shape the sounds produced by the vocal cords, contributing to the production of speech.
3. Respiration: The pharyngeal muscles assist in maintaining an open airway during breathing, especially during sleep and when the upper airways are obstructed.

The pharyngeal muscles consist of three layers: the outer circular muscle layer, the middle longitudinal muscle layer, and the inner inferior constrictor muscle layer. The specific muscles that make up these layers include:

1. Superior constrictor muscle (outer circular layer)
2. Middle constrictor muscle (middle longitudinal layer)
3. Inferior constrictor muscle (inner inferior constrictor layer)
4. Stylopharyngeus muscle
5. Salpingopharyngeus muscle
6. Palatopharyngeus muscle
7. Buccinator muscle (partially contributes to the middle longitudinal layer)

These muscles work together to perform their various functions, and any dysfunction in these muscles can lead to problems like swallowing difficulties (dysphagia), speech impairments, or respiratory issues.

Myoclonus is a medical term that describes a quick, involuntary jerking muscle spasm. These spasms can happen once or repeat in a series, and they can range from mild to severe in nature. Myoclonus can affect any muscle in the body and can be caused by several different conditions, including certain neurological disorders, injuries, or diseases. In some cases, myoclonus may occur without an identifiable cause.

There are various types of myoclonus, classified based on their underlying causes, patterns of occurrence, and associated symptoms. Some common forms include:

1. Action myoclonus: Occurs during voluntary muscle movements
2. Stimulus-sensitive myoclonus: Triggered by external or internal stimuli, such as touch, sound, or light
3. Physiological myoclonus: Normal muscle jerks that occur during sleep onset (hypnic jerks) or during sleep (nocturnal myoclonus)
4. Reflex myoclonus: Result of a reflex arc activation due to a peripheral nerve stimulation
5. Epileptic myoclonus: Part of an epilepsy syndrome, often involving the brainstem or cortex
6. Symptomatic myoclonus: Occurs as a result of an underlying medical condition, such as metabolic disorders, infections, or neurodegenerative diseases

Treatment for myoclonus depends on the specific type and underlying cause. Medications, physical therapy, or lifestyle modifications may be recommended to help manage symptoms and improve quality of life.

Hexamethonium is defined as a ganglionic blocker, which is a type of medication that blocks the activity at the junction between two nerve cells (neurons) called the neurotransmitter receptor site. It is a non-depolarizing neuromuscular blocking agent, which means it works by binding to and inhibiting the action of the nicotinic acetylcholine receptors at the motor endplate, where the nerve meets the muscle.

Hexamethonium was historically used in anesthesia practice as a adjunct to provide muscle relaxation during surgical procedures. However, its use has largely been replaced by other neuromuscular blocking agents that have a faster onset and shorter duration of action. It is still used in research settings to study the autonomic nervous system and for the treatment of hypertensive emergencies in some cases.

It's important to note that the use of Hexamethonium requires careful monitoring and management, as it can have significant effects on cardiovascular function and other body systems.

"Torque" is not a term that has a specific medical definition. It is a physical concept used in the fields of physics and engineering, referring to a twisting force that causes rotation around an axis. However, in certain medical contexts, such as in discussions of spinal or joint biomechanics, the term "torque" may be used to describe a rotational force applied to a body part. But generally speaking, "torque" is not a term commonly used in medical terminology.

In medical terms, the "head" is the uppermost part of the human body that contains the brain, skull, face, eyes, nose, mouth, and ears. It is connected to the rest of the body by the neck and is responsible for many vital functions such as sight, hearing, smell, taste, touch, and thought processing. The head also plays a crucial role in maintaining balance, speech, and eating.

Unmyelinated nerve fibers, also known as unmyelinated axons or non-myelinated fibers, are nerve cells that lack a myelin sheath. Myelin is a fatty, insulating substance that surrounds the axon of many nerve cells and helps to increase the speed of electrical impulses traveling along the nerve fiber.

In unmyelinated nerve fibers, the axons are surrounded by a thin layer of Schwann cell processes called the endoneurium, but there is no continuous myelin sheath. Instead, the axons are packed closely together in bundles, with several axons lying within the same Schwann cell.

Unmyelinated nerve fibers tend to be smaller in diameter than myelinated fibers and conduct electrical impulses more slowly. They are commonly found in the autonomic nervous system, which controls involuntary functions such as heart rate, blood pressure, and digestion, as well as in sensory nerves that transmit pain and temperature signals.

Sneezing is an involuntary, forceful expulsion of air through the nose and mouth, often triggered by irritation or inflammation in the nasal passages. It is a protective reflex that helps to clear the upper respiratory tract of irritants such as dust, pollen, or foreign particles. The sneeze begins with a deep inspiration of air, followed by closure of the glottis (the opening between the vocal cords) and contraction of the chest and abdominal muscles. This builds up pressure in the lungs, which is then suddenly released through the nose and mouth as the glottis opens and the velum (the soft tissue at the back of the roof of the mouth) rises to block the nasal passage. The result is a powerful burst of air that can travel at speeds of up to 100 miles per hour, expelling mucus and any trapped irritants along with it.

Spinal injections, also known as epidural injections or intrathecal injections, are medical procedures involving the injection of medications directly into the spinal canal. The medication is usually delivered into the space surrounding the spinal cord (the epidural space) or into the cerebrospinal fluid that surrounds and protects the spinal cord (the subarachnoid space).

The medications used in spinal injections can include local anesthetics, steroids, opioids, or a combination of these. The purpose of spinal injections is to provide diagnostic information, therapeutic relief, or both. They are commonly used to treat various conditions affecting the spine, such as radicular pain (pain that radiates down the arms or legs), disc herniation, spinal stenosis, and degenerative disc disease.

Spinal injections can be administered using different techniques, including fluoroscopy-guided injections, computed tomography (CT) scan-guided injections, or with the help of a nerve stimulator. These techniques ensure accurate placement of the medication and minimize the risk of complications.

It is essential to consult a healthcare professional for specific information regarding spinal injections and their potential benefits and risks.

"Neonatal reflexes". Retrieved 24 May 2017. "Medline plus: Babinski reflex". Retrieved 24 May 2017. Neelon, Francis A; Harvey, ... The plantar reflex is a reflex elicited when the sole of the foot is stimulated with a blunt instrument. The reflex can take ... of the hallux is known as the Babinski response or Babinski sign, named after the neurologist Joseph Babinski. The presence of ... The Hoffmann's reflex is sometimes described as the upper limb equivalent of the Babinski sign because both indicate upper ...
It is the reflex hammer of choice of the UK neurologist. The Babinski reflex hammer was designed by Joseph Babiński in 1912 and ... The Babinski reflex hammer. Neurology. 1999 Aug 11;53(3):655 PMID 10449145 Marshall GL, Little JW. Deep tendon reflexes: a ... A reflex hammer is a medical instrument used by practitioners to test deep tendon reflexes. Testing for reflexes is an ... Reflex hammers can also be used for chest percussion. Prior to the development of specialized reflex hammers, hammers specific ...
... often combined with the Babinski reflex test. Jaw jerk reflex Knee jerk or patellar reflex - a kick caused by striking the ... stimulating the C5 and C6 reflex arcs. Brain's reflex Bulbocavernosus reflex Cervico-collic reflex Cervico-ocular reflex - ... Diving reflex Enterogastric reflex Galant reflex - a primitive reflex in infants up to four months of age, a rotation of the ... Glabellar reflex Golgi tendon reflex Hering-Breuer reflex - is a reflex triggered to prevent over-inflation of the lung ...
Rossolimo's reflex at Who Named It? v t e (Articles with short description, Short description matches Wikidata, Symptoms and ... It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. The sign is named ... Kumar SP, Ramasubramanian D (December 2000). "The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-8. PMID 11146592. ... signs: Nervous system, Reflexes, All stub articles, Medical sign stubs). ...
"The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-8. PMID 11146592. Retrieved 2009-04-13. Schäffer's reflex at Who ... It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. The sign takes its ... Schaeffer's sign is a clinical sign in which squeezing the Achilles tendon elicits an extensor plantar reflex. ... Reflexes, All stub articles, Medical sign stubs). ...
Another significant difference between Hoffmann's reflex and the Babinski sign is their mechanism of reflex. Hoffmann's reflex ... Hoffmann's reflex is often erroneously confused with Babinski's. However the two reflexes are quite different, and should not ... On the other hand, the plantar reflex is more complicated and not a deep tendon reflex, and its pathway is both more ... Usually considered a pathological reflex in a clinical setting, the Hoffmann's reflex has also been used as a measure of spinal ...
"Hypertonus Spasticity, Rigidity" and "Babinski's Reflex, Sign of". Encyclopedia of Neuroscience. Edited by George Adelman, ...
The Babinski reflex is a sign of neurological abnormality (e.g., upper motor neuron lesion) in adults. The Galant reflex, also ... An abnormal plantar reflex (Babinski sign) occurs when upper motor neuron control over the flexion reflex circuit is ... In addition to the reflexes previously mentioned, they include the palmomental reflex, snout reflex, glabellar reflex or "tap" ... Reflexes vary in utility. Some reflexes hold a survival value (e.g., the rooting reflex, which helps a breastfed infant find ...
Joseph Babinski: neurologist, discoverer of the Babinski reflex. Stefan Banach: considered one of the world's most important ... "Joseph Babinski: a biography". thelancet.com. Archived from the original on 30 April 2023. Retrieved 5 May 2023. Lewandowski, ... Jerzy Konorski: neurophysiologist, discoverer of secondary conditioned reflexes and operant conditioning. He also proposed the ...
The Chaddock reflex is a diagnostic reflex similar to the Babinski reflex. Chaddock's sign is present when stroking of the ... v t e (Articles with short description, Short description is different from Wikidata, Diagnostic neurology, Reflexes, All stub ... Goetz CG (2002). "History of the extensor plantar response: Babinski and Chaddock signs". Seminars in Neurology. 22 (4): 391-8 ...
Wartenberg, Robert (June 1951). "Babinski Reflex and Marie-foix Flexor Withdrawal Reflex: Historical Notes". AMA Archives of ...
Gordon's paradoxical flexor reflex at Who Named It? v t e (Articles with short description, Short description is different from ... It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. The sign is named ... Gordon's sign is a clinical sign in which squeezing the calf muscle elicits an extensor plantar reflex. ... Kumar SP, Ramasubramanian D (December 2000). "The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-8. PMID 11146592. ...
The presence of the Babinski sign is an abnormal response in adulthood. Normally, during the plantar reflex, it causes plantar ... Increased deep tendon reflex (DTR) Pronator drift These are the neural tracts which descend in the ventral horn of the spinal ... In Babinski's sign, there is dorsiflexion of the big toe and abduction of the other toes. Physiologically, it is normally ... The presence of the Babinski sign after 12 months is the sign of a non-specific upper motor neuron lesion. ...
Hoffman's sign and Babinski reflex may be present and indicative of upper motor neuron damage.[citation needed] Treatment for ... Hyperreflexia is another key feature of PLS as seen in patients presenting with the Babinski's sign. Some people present with ...
Translation of J Babinski: tendon reflexes and bone reflexes: an authorized translation. Interstate Med J 1914;21:75-84, 178- ... later publishing a translation of Babinski's work. Chaddock introduced his eponymous reflex in 1911, calling it the External ... A new reflex phenomenon in the hand: the wrist-sign. Interstate Med J 1912;19:127-131 "Untitled". Allegan Gazette. 1936-07-23. ... Baddock returned to Europe in 1897, spending most of the time as assistant to Joseph Babinski. On his return to the United ...
In the motor system examination, the left upper and lower extremity muscle power were 3/5 level and her Babinski reflex was ... "Babinski-Nageotte syndrome". Who Named It?. Retrieved 2010-12-30. GmbH, Symptoma. "Babinski-Nageotte Syndrome (Babinski ... Acharya, Aninda B.; Jamil, Radia T.; Dewey, Jeffrey J. (2020), "Babinski Reflex", StatPearls, Treasure Island (FL): StatPearls ... Damage anywhere on the CST can determine the presence of the Babinski sign. [citation needed] The Babinski sign can be the ...
Pupillary reaction to light may be sluggish, but the corneal reflexes are preserved. Paresis and Babinski sign may be present. ... Examination will reveal decreased muscle tone of the extremities and depression of tendon reflexes. ...
He is best known for his 1896 description of the Babinski sign, a pathological plantar reflex indicative of corticospinal tract ... Babinski lived with his younger brother, Henri Babinski, a distinguished engineer and famous cook who, as "Ali Baba," published ... Biography of Joseph Babinski, from whonamedit.com Joseph Jules François Félix Babinski (1857-1932) - short biography by Janusz ... Babinski-Jarkowski rule: For localization of a medullary lesion. Named with neurologist Jean Jarkowski. Babinski-Nageotte ...
This can occur when there is no movement of the toes, and is part of the extensor plantar response (Babinski's sign). The sign ... Brissaud's reflex at Who Named It? v t e (Medical signs, Reflexes, All stub articles, Medical sign stubs). ... Brissaud's reflex is a clinical sign in which stroking the sole of the foot elicits contraction of tensor fasciae latae. ...
It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. It is named after the ... Gonda's sign is a clinical sign in which flexing and then suddenly releasing the fourth toe elicits an extensor plantar reflex ... "The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-8. PMID 11146592. Retrieved 2009-04-13. v t e (Articles with short ... Reflexes, All stub articles, Medical sign stubs). ...
It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. The sign is named ... sign is a clinical sign in which the patient's attempt to flex the knee against resistance elicits an extensor plantar reflex. ... Kumar SP, Ramasubramanian D (December 2000). "The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-8. PMID 11146592. ... Reflexes, All stub articles, Medical sign stubs). ...
Botticelli's Madonna may be the earliest known depiction of the neurological Babinski reflex. Botticelli is also known for his ... ISBN 978-3-8228-5992-6. Massey, E. W.; Sanders, L. (1 January 1989). "Babinski's Sign in Medieval, Renaissance, and Baroque Art ...
Joseph Babinski, a neurologist best known for his 1896 description of the Babinski sign, a pathological plantar reflex ... "Joseph Babinski: a biography". thelancet.com. Retrieved 30 April 2023. Iłowiecki, Maciej (1981). Dzieje nauki polskiej. ... Jerzy Konorski, Polish neurophysiologist; he discovered secondary conditioned reflexes and operant conditioning and proposed ...
... and the plantar reflex may be abnormal, namely extending rather than flexing (Babinski's sign) in severe encephalopathy. A ... are at risk of obstructing their airway due to decreased protective reflexes such as the gag reflex. This can lead to ... In the third stage, neurological examination may reveal clonus and positive Babinski sign. Coma and seizures represent the most ...
The extensor plantar reflex (Babinski sign) is usually absent. Muscle paresis/paralysis, hypotonia/atonia, and hyporeflexia/ ... Hyporeflexia - Along with deep reflexes even cutaneous reflexes are also decreased or absent. Strength - weakness is limited to ...
It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. Kumar SP, ... sign in which scratching along the inner side of the extensor hallucis longus tendon elicits an extensor plantar reflex. ... Ramasubramanian D (December 2000). "The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-18. PMID 11146592. Retrieved ... Reflexes, All stub articles, Medical sign stubs). ...
It is found in patients with pyramidal tract lesions, and is one of a number of Babinski-like responses. The sign is named ... a clinical sign in which vigorous abduction followed by the sudden release of the little toe causes an extensor plantar reflex ... "The Babinski sign--a reappraisal". Neurol India. 48 (4): 314-8. PMID 11146592. Retrieved 2009-04-13. v t e (Articles with short ... Reflexes, All stub articles, Medical sign stubs). ...
... or Bing's reflex is a clinical sign in which pricking the dorsum of the foot or toe with a pin causes extension of ... It is one of a number of Babinski-like responses.[citation needed] This sign is named after Paul Robert Bing.[citation needed] ... ISBN 978-1-85070-333-4. Bing's reflex or sign at Who Named It? v t e (Articles with short description, Short description is ...
The occurrence of upper motor neuron symptoms such as brisk reflexes, spasticity, or a Babinski sign would indicate a ... brisk reflexes spasticity Babinski's sign emotional lability The importance of correctly recognizing progressive muscular ...
Other abnormal reflexes such as Hoffmann's reflex, upward response of plantar reflex (Babinski response), and Wartenberg's sign ... or weakness or absent tendon reflex of the muscle supplied by the nerve. This symptom can be provoked by neck extension. ...
The Babinski reflex occurs after the sole of the foot has been firmly stroked. The big toe then moves upward or toward the top ... The Babinski reflex occurs after the sole of the foot has been firmly stroked. The big toe then moves upward or toward the top ... Reflexes are responses that occur when the body receives a certain stimulus. ... Reflexes are responses that occur when the body receives a certain stimulus. ...
Babinski" by people in this website by year, and whether "Reflex, Babinski" was a major or minor topic of these publications. ... "Reflex, Babinski" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Reflex, Babinski" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Reflex, Babinski". ...
Order your Reflex Hammer Babinski Telescoping ✓ in-house name and logo print ✓ all items in stock ✓ your partner for healthcare ... "Reflex Hammer Babinski Telescoping" Quality Babinski hammer for use by physicians to test reflexes. This Babinski hammer is ... Quality Babinski hammer for use by physicians to test reflexes. This Babinski hammer is telescoping for compact storage.Feat… ...
... reflex hammer. Intelligently designed. Ergonomic handle. Removable rubber tip. ... Subscribe to receive 10% off your first order, updates, access to exclusive deals on stethoscopes, sphygmomanometers, reflex ... MDF® Instruments has been crafting stethoscopes, sphygmomanometers, and reflex hammers since 1971. With our passion, innovation ...
Reflex Hammer ✓Free shipping ✓Lifetime warranty ✓90-Day guarantee ✓Free stethoscope parts for life. Best gifts ideas for nurses ... Quality is our reflex. All MDF reflex hammers qualify for a lifetime warranty after registration of the unit. MDF® reflex ... Quality is our reflex. All MDF reflex hammers qualify for a lifetime warranty after registration of the unit. MDF® reflex ... The reflex hammer has a good weight to it where it doesnt require a lot of force to elicit a reflex, even when the hammer ...
... are reflex actions originating in the central nervous system that are exhibited by normal ... Babinski reflex. Often confused with the plantar reflex, the Babinski reflex is also present at birth and fades around the ... The reflex is caused by a lack of myelination in the corticospinal tract in young children. The Babinski reflex is a sign of ... Moro reflex. Main article: Moro reflex. This is sometimes referred to as the startle reaction, startle response, startle reflex ...
"Neonatal reflexes". Retrieved 24 May 2017. "Medline plus: Babinski reflex". Retrieved 24 May 2017. Neelon, Francis A; Harvey, ... The plantar reflex is a reflex elicited when the sole of the foot is stimulated with a blunt instrument. The reflex can take ... of the hallux is known as the Babinski response or Babinski sign, named after the neurologist Joseph Babinski. The presence of ... The Hoffmanns reflex is sometimes described as the upper limb equivalent of the Babinski sign because both indicate upper ...
Positive Babinski reflex. *Separated sutures of the skull bones. Older children with brain tumors may have the following ...
This reflex helps your baby reduce their risk of choking, and so your baby wont be very successful at eating solids until this ... Most babies have extrusion reflex at birth, and it usually disappears between 4 and 6 months of age. ... Babinski. Babys big toe bends backward and toes splay when the sole of their foot is stroked. Seen in most term and premature ... This reflex works together with the sucking reflex, which develops between 32 and 36 weeks of gestation. The sucking reflex ...
Babinski reflex. As the infants foot is stroked, the toes will extend upward. ... In newborns and infants, reflexes called infant reflexes (or primitive reflexes) are evaluated. Each of these reflexes ... Reflexes in the older child and adult. These are usually examined with the use of a reflex hammer. The reflex hammer is used at ... Moros reflex (or startle reflex). A quick change in the infants position will cause the infant to throw the arms outward, ...
Meningoencephalitis: nuchal rigidity; drowsiness; desorientation; bilateral Babinski reflex and seizure. 1,890. 12. 1.10. Serum ...
... in whom rapid muscle stretch does not elicit reflex muscle activity beyond the normal short-latency tendon reflex, patients ... The effect of operant-conditioning balance training on the down-regulation of spinal H-reflexes in a spastic patient. Neurosci ... The H reflex in rigid, spastic and normal subjects. Arch Neurol. 1983. 8:591-596. ... Spasticity usually is accompanied by paresis and other signs, such as increased stretch reflexes, which collectively are called ...
... and deep tendon reflexes. Babinski reflexes are downgoing bilaterally. Vision screening is normal (20/20 bilaterally). ...
The voiding reflexes of the lower urinary tract-the primitive voiding reflex-remain intact. Affected individuals show signs of ... Affected patients will demonstrate extensor plantar response and a positive Babinski sign. ... While conscious control of this reflex develops after infancy, the primitive voiding reflex may reappear with spinal cord ... which by default attempts to trigger the voiding reflex. This voiding reflex causes the urethral sphincters to open while ...
The voiding reflexes of the lower urinary tract-the primitive voiding reflex-remain intact. Affected individuals show signs of ... Affected patients will demonstrate extensor plantar response and a positive Babinski sign. ... While conscious control of this reflex develops after infancy, the primitive voiding reflex may reappear with spinal cord ... which by default attempts to trigger the voiding reflex. This voiding reflex causes the urethral sphincters to open while ...
Babinski J., Froment J. (1918). Hysteria or pithiatism and reflex nervous disorders in the neurology of war. London: University ...
Look no further than ScripHessco for low prices on Reflex Hammers, Monofilament, Wartenburg Pinwheels and more! ... Sensory Testers & Reflex Hammers ScripHessco offers a large selection of sensory testers to add to your diagnostic tools. The ...
... oculovestibular reflex abnormalities, mild hyperreflexia (no spasticity or Babinski signs) ... and exaggerated deep tendon reflexes; one patient had optic atrophy; seizures common [30] ...
Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensorplantar reflexes (Babinski reflex). ...
Ankle reflexes were absent, and vibration sensation was reduced at the toes. Babinski and Chaddock signs were absent. From 39 ... His reflexes became brisk at patellar and biceps brachii tendons despite the prominent weakness in the subserved muscles. At ...
No Babinski sign and no clonus, my reflexes.... *Tavoh. *Thread. *. Nov 7, 2017. ... back bfs bulbar bulbar als bulbar onset clinical confusing death diagnosis dysphagia early emg fatigue fingers mnd onset reflex ...
Babinski reflex.The Babinski can reoccur in people if this group of nerves gets damaged and is not able to block this reflex ... This reflex is usually present in babies for the first 6 or so months of their life and goes away once a certain group of ... Strokes, aneurysms, and tumors are some things that can cause this.Bilateral just means that the reflex is present in both feet ... The Babinski sign is a reflex that happens when the bottom of a persons foot is stroked and the big toe curls up in response. ...
FALSE- THE BABINSKI REFLEX IS A NORMAL REFLEX IN INFANTS, BUT DISAPPEARS AROUND AGE 2. ... WHEN ASSESSING REFLEXES, WHAT WOULD A FINDING OF CLONUS MEAN?. Definition. PT IS EXHIBITING A SHORT, JERKING CONTRACTION OF THE ... WHAT TENDONS CAN BE/ARE USED WHEN ASSESSING DEEP REFLEXES?. Definition. BICEPS, BRACHIAL RADIALIS, TRICEPS, PATELLAR, ACHILLES ... WHAT IS IT CALLED WHEN A PERSON HAS A REFLEX SCORE OF 1+ OR 0?. ... WHAT IS THE PURPOSE OF A REFLEX?. Definition. SERVES AS A ...
... from a peripheral neuropathy on examination by eliciting hyperactive deep tendon reflexes and a positive Babinski sign. The ...
Bilateral Babinskis reflex was present, the abdominal reflexes were absent, the tendon and periosteal reflexes were ...
Neurological examination revealed spastic paraplegia, exaggerated patellar tendon reflexes, and positive Babinski and Chaddock ... His upper limbs appeared normal except for symmetrically brisk tendon reflexes. Blood cholesterol level was normal, but the ... and bilateral hyperactive deep tendon reflexes. The volume of residual urine in the patients bladder was 140 mL. Anal ...
Six taps were administered with a Babinski/Rabiner reflex hammer and the resulting reflex was classified into one of four ... Scapulohumeral reflex was present in 35 of our 40 subjects (878.5%). In the 70-79 year old age group, scapulohumeral reflex was ... Clinically, the scapulohumeral reflex may be reliable, along with the biceps, brachioradialis, and triceps reflex, as an ... The occurrence rate of the scaulohumeral reflex was greater than that of the triceps reflex, which is used in standard clinical ...
4. Reflex Hammer. The humble reflex hammer can be used to diagnose joint reflexes as well as bone fractures in the joint. Go ... with the classic triangle-head Taylor hammer, or choose from several other designs, such as the Buck and Babinski hammers. Most ...
  • Bilateral Babinski's reflex was present, the abdominal reflexes were absent, the tendon and periosteal reflexes were hyperactive. (who.int)
  • Deep tendon reflexes are 1-2+, with absent bilateral ankle clonus. (medscape.com)
  • If the tumor is at the level of the cauda equina, muscle flaccidity, muscle wasting, weakness, and progressive diminution in tendon reflexes are characteristic. (health-care-clinic.org)
  • Neurological examination showed cerebellar ataxia and dysmetria of four limbs, tetrapyramidal syndrome with brisk deep tendon reflexes of four limbs, and bilateral Babinski's signs. (bmj.com)
  • He was not able to tetraplegia, loss of sensation and sphincter move any limbs, muscle tone was decreased disturbance, and in rare cases it can cause and deep tendon reflexes were absent in his respiratory insufficiency. (who.int)
  • He has brisk tendon reflexes and positive Babinski's sign. (bvsalud.org)
  • MDF® Instruments has been crafting stethoscopes, sphygmomanometers, and reflex hammers since 1971. (mdfinstruments.com)
  • All MDF reflex hammers qualify for a lifetime warranty after registration of the unit. (mdfinstruments.ca)
  • MDF® reflex hammers with defects in material or craftsmanship will be replaced or repaired without charge for the life of the instrument. (mdfinstruments.ca)
  • It may be done with instruments, such as lights and reflex hammers. (rochester.edu)
  • Go with the classic triangle-head Taylor hammer, or choose from several other designs, such as the Buck and Babinski hammers. (minoritynurse.com)
  • Quality Babinski hammer for use by physicians to test reflexes. (nursesdna.com)
  • This Babinski hammer is telescoping for compact storage. (nursesdna.com)
  • What is a Babinski Reflex Hammer? (mdfinstruments.com)
  • I bought this reflex hammer because I wanted one that could fit into my pocket without half of it sticking out all the time. (mdfinstruments.ca)
  • The reflex hammer has a good weight to it where it doesn't require a lot of force to elicit a reflex, even when the hammer isn't extended. (mdfinstruments.ca)
  • MDF® has re-invented the original Babinski hammer by adding a patented Spring-loaded Locking System (SLS) to securely lock the articulating head into place while in use. (mdfinstruments.ca)
  • The MDF® Babinski Telescoping 2.0® Hammer is meticulously handcrafted with attention to detail and extreme quality standards, and it also comes with a lifetime warranty. (mdfinstruments.ca)
  • The articulating Babinski Hammer head is surmounted with a chrome-plated brass disc grooved to house the silicone bumper and is weighted for more controlled striking. (mdfinstruments.ca)
  • These are usually examined with the use of a reflex hammer. (rochester.edu)
  • The reflex hammer is used at different points on the body to test numerous reflexes, which are noted by the movement that the hammer causes. (rochester.edu)
  • The humble reflex hammer can be used to diagnose joint reflexes as well as bone fractures in the joint. (minoritynurse.com)
  • MDF Tromner Hammer - Light (AKA Troemner) is a versatile 4-in-1 multifuntional dual-mallet type reflex hammer. (giftespot.com)
  • In addtion to the myotatic reflex function of the tradtional Tromner, MDF re-designed the Tromner Hammer - Light to also elicit plantar and cutaneous reflexes on adult and pediatric patients with less effort and greater patient comfort. (giftespot.com)
  • Learn more about our engraving service and individualise selected medical products, such as the Tromner reflex hammer, with a personal laser engraving. (praxisdienst.com)
  • His reflexes became brisk at patellar and biceps brachii tendons despite the prominent weakness in the subserved muscles. (bmj.com)
  • Interruption of the lateral corticospinal tracts, the lateral spinal thalamic tract, and at times the posterior columns produces a picture of a spastic, weak leg with brisk reflexes and a strong leg with loss of pain and temperature sensation. (medscape.com)
  • The phrase "negative Babinski sign" is sometimes used for the normal flexor plantar response. (wikipedia.org)
  • The final arcing movement is absent in the original Babinski plantar response test. (medicinehack.com)
  • The built-in brush at the base of the handle can be easily removed to elicit cutaneous reflexes. (mdfinstruments.ca)
  • Ankle reflexes were absent, and vibration sensation was reduced at the toes. (bmj.com)
  • Babinski and Chaddock signs were absent. (bmj.com)
  • Babinski pathophysiological mechanisms and trigger sign was absent. (who.int)
  • The Hoffmann's reflex is sometimes described as the upper limb equivalent of the Babinski sign because both indicate upper motor neuron dysfunction. (wikipedia.org)
  • Upper motor neuron dysfunction disinhibits lower motor neurons, resulting in increased muscle tone (spasticity) and increased muscle stretch reflexes (hyperreflexia). (msdmanuals.com)
  • However, upper motor neuron dysfunction can decrease tone and reflexes if motor paralysis is sudden and severe (eg, in spinal cord transection, in which tone first decreases, then increases gradually over days to weeks) or if the lesion damages the motor cortex of the precentral gyrus and not nearby motor association areas. (msdmanuals.com)
  • Primitive reflexes are reflex actions originating in the central nervous system that are exhibited by normal infants but not neurologically in tact adults, in response to particular stimuli. (bionity.com)
  • Reflexes are involuntary actions that arise in response to certain stimuli. (healthline.com)
  • Any of the reflexes initiated by several stimuli originating in widely separated receptors whose impulses follow the final common path to the effector organ and reinforce one another. (unboundmedicine.com)
  • Reflexes are automatic responses to stimuli that protect your baby. (nestedbean.com)
  • The startle reflex is a baby's natural response to new (and loud) stimuli as they adjust to life outside of the womb. (nestedbean.com)
  • In one study of 256 healthy infants, the response to testing was extensor in 73.8%, flexor in 8.9%, and equivocal in 17.3% This extensor response occurs because the corticospinal pathways that run from the brain down the spinal cord are not fully myelinated at this age, so the reflex is not inhibited by the cerebral cortex. (wikipedia.org)
  • Loss of normal adult descending pyramidal control of the reflex arc to suppress extensor withdrawal results in the upgoing toes in the plantar reflex known as Babinski's sign. (wikipedia.org)
  • An extensor plantar (Babinski) reflex is specific for corticospinal tract dysfunction. (msdmanuals.com)
  • The lightweight ergonomic HDP handle is designed for increased control of force in percussions to elicit myotatic reflexes. (giftespot.com)
  • Babinski reflex is one of the normal reflexes in infants and in children up to 2 years old. (medlineplus.gov)
  • A reflex found in normal infants consisting of dorsiflexion of the HALLUX and abduction of the other TOES in response to cutaneous stimulation of the plantar surface of the FOOT. (ouhsc.edu)
  • The presence of the Babinski sign can identify disease of the spinal cord and brain in adults, and also exists as a primitive reflex in infants. (wikipedia.org)
  • If elicited in an adult, it indicates damage to the central nervous system, but it is a normal reflex in infants (see below). (wikipedia.org)
  • In newborns and infants, reflexes called infant reflexes (or primitive reflexes) are evaluated. (rochester.edu)
  • Swimming reflex - Laid horizontally on stomachs, infants stretch out their arms and legs. (freezingblue.com)
  • Palmar grasping reflex - When something touches the palms, infants grip it tightly. (freezingblue.com)
  • Moro reflex - When startled, infants fling their arms outward, then bring back to chest as if to hold on to something, while crying and wide-open eyes. (freezingblue.com)
  • [1] These primitive reflexes are also called infantile , infant or newborn reflexes . (bionity.com)
  • Older children and adults with atypical neurology (for instance, people with cerebral palsy ) may retain these reflexes and primitive reflexes may re-appear in adults due to certain neurological conditions including, but not limited to, dementia , traumatic lesions , and strokes . (bionity.com)
  • Primitive reflexes are also tested with suspected brain injury to test the functioning of the frontal lobe. (bionity.com)
  • Atypical primitive reflexes are also being researched as potential early warning signs of autistic spectrum disorders . (bionity.com)
  • although this reflex is based in our body's primitive walking motion, it disappears by about 2 months of age. (thoughtfulparent.com)
  • While sucking is a primitive motor reflex, not all babies get the hang of it at first. (nestedbean.com)
  • In response to stimulus, primitive reflexes are automatically triggered. (kidsrush.com)
  • [7] Bilateral absence of the reflex may mean damage to the infant's central nervous system while a unilateral absence could mean an injury due to birth trauma such as a fractured clavicle or injury to the brachial plexus . (bionity.com)
  • Bilateral just means that the reflex is present in both feet. (answers.com)
  • One patient who referred disease duration of more than 16 years, showed diminished deep reflexes, bilateral Babinski's sign, diminished sensation of vibration, abnormal bladder function and back pain. (scielo.br)
  • Um paciente que referiu a duração da doença por mais de 16 anos, mostrou hiporreflexia, sinal de Babinski bilateral, uma sensibilidade vibratória diminuída, disfunção urinária e dor lombar. (scielo.br)
  • An upward response (extension) of the hallux is known as the Babinski response or Babinski sign, named after the neurologist Joseph Babinski. (wikipedia.org)
  • This is what Joseph Babinski did in the year 1896. (medicinehack.com)
  • Motor symptoms include asymmetrical spastic muscle weakness, decreased muscle tone, exaggerated reflexes, and a positive Babinski's sign. (health-care-clinic.org)
  • It is more commonly known as the Moro response or Moro reflex after its discoverer, pediatrician Ernst Moro. (bionity.com)
  • The Moro reflex is present at birth, peaks in the first month of life and begins to disappear around 2 months of age. (bionity.com)
  • When the Moro reflex is triggered (usually by a loud noise or sudden movement), the baby will throw their arms and legs out and quickly bring them back in towards their chest. (nestedbean.com)
  • He said the best instrument to elicit the Babinski reflex (toes curl down when the sole is stroked) was a Bentley key. (coinbooks.org)
  • The Babinski sign can indicate upper motor neuron lesion constituting damage to the corticospinal tract. (wikipedia.org)
  • Reflexes are responses that occur when the body receives a certain stimulus. (medlineplus.gov)
  • Note that spasticity and hyperactive reflexes may not be present with an acute lesion. (medscape.com)
  • The Rooting reflex is present at birth and assists in breastfeeding, disappearing at around four months of age as it gradually comes under voluntary control. (bionity.com)
  • It is linked with the rooting reflex and breastfeeding, and causes the child to instinctively suck at anything that touches the roof of their mouth. (bionity.com)
  • The rooting reflex is an essential motor reflex that is present at birth. (nestedbean.com)
  • The rooting reflex develops around 28 weeks gestation and lasts about 4 to 6 months. (nestedbean.com)
  • The suck reflex works with the rooting reflex to help your newborn get nutrition. (nestedbean.com)
  • While the rooting reflex is stimulated by a touch on the outside of the cheek, the suck reflex takes over once that something touches the roof of the baby's mouth. (nestedbean.com)
  • [2] [3] An individual with cerebral palsy and typical intelligence can learn to suppress these reflexes, but the reflex might resurface under certain conditions such as during an extreme startle reaction. (bionity.com)
  • This is sometimes referred to as the startle reaction, startle response, startle reflex or embrace reflex. (bionity.com)
  • Moro's reflex (or startle reflex). (rochester.edu)
  • Once this reflex disappears, babies typically don't startle themselves awake when sleeping as easily. (thoughtfulparent.com)
  • Swaddling helps to reduce the startle reflex because it restricts your baby's movements creating a womb-like environment. (nestedbean.com)
  • The other two patients (with one and six years of disease duration) complained of weakness in one leg, increased deep reflexes and back pain. (scielo.br)
  • Occasionally, a pathological plantar reflex is the first and only indication of a serious disease process and a clearly abnormal plantar reflex often prompts detailed neurological investigations, including CT scanning of the brain or MRI of the spine, as well as lumbar puncture for the study of cerebrospinal fluid. (wikipedia.org)
  • She checked my reflexes and didn't really note anything abnormal (only did the patellar reflexes for some reason). (alsforums.com)
  • When the Babinski reflex is present in a child older than 2 years or in an adult, it is often a sign of a central nervous system disorder. (medlineplus.gov)
  • It is also known as the Babinski Sign. (wikipedia.org)
  • As the lesion responsible for the sign expands, so does the area from which the afferent Babinski response may be elicited. (wikipedia.org)
  • The Babinski sign is a reflex that happens when the bottom of a persons foot is stroked and the big toe curls up in response. (answers.com)
  • It's important to note that the presence of this reflex in individuals over 2 years of age can be the sign of a nervous system problem . (thoughtfulparent.com)
  • You might have heard of the plantar reflex or "Babinski sign. (nestedbean.com)
  • The Babinski sign is considered normal up to 24 months of age. (nestedbean.com)
  • The pons relays afferent information from the bladder to higher brain centers, which in turn communicate with the periaqueductal gray matter, a relay station that collects higher brain center intput and processes this in order to signal the PMC to trigger or suppress the voiding reflex. (medscape.com)
  • In a simple reflex this includes a sensory receptor, afferent or sensory neuron, reflex center in the brain or spinal cord, one or more efferent neurons, and an effector organ. (unboundmedicine.com)
  • Most reflexes, however, are more complicated and include internuncial or associative neurons intercalated between afferent and efferent neurons. (unboundmedicine.com)
  • even tho my neurologist said 'your exam was fine' during our 3rd appointment I remember my legs jerked out a bit during the reflexes (patellar and ankle). (alsforums.com)
  • Hyperactive reflexes in the legs with less active arm reflexes suggest thoracic myelopathy (although a cervical lesion is also possible). (emcrit.org)
  • Why do babies have an extrusion reflex? (healthline.com)
  • Babies are born with different reflexes that help them survive the first months of life. (healthline.com)
  • The extrusion or tongue-thrust reflex helps protect babies from choking or aspirating food and other foreign objects and helps them to latch onto a nipple. (healthline.com)
  • While it's not exactly clear when the extrusion reflex first develops in the womb, it's present in most newborn babies. (healthline.com)
  • The disappearance of the extrusion reflex helps babies start to wean from the breast or bottle, and learn to eat purees, cereals, or softened table foods. (healthline.com)
  • Babies born prematurely may need to wait longer than the standard 4 to 6 months to start solids, whether or not the extrusion reflex is still present. (healthline.com)
  • This reflex is usually present in babies for the first 6 or so months of their life and goes away once a certain group of nerves running from the brain to muscles in the lower limbs is fully developed and functions to block the Babinski reflex. (answers.com)
  • [5] The reflex normally disappears by three to four months of age, [6] though it may last up to six months. (bionity.com)
  • This reflex disappears as an automatic response and reappears as a voluntary behavior at around a year old. (bionity.com)
  • Each of these reflexes disappears at a certain age as the infant grows. (rochester.edu)
  • this reflex that occurs when a baby is moved abruptly usually disappears by around 6 months old. (thoughtfulparent.com)
  • although the origin of this reflex is unknown, it usually disappears by about 2 years of age. (thoughtfulparent.com)
  • In adults, this reflex is not normal and often indicates a problem with the brain or spinal cord. (medlineplus.gov)
  • Babinski reflexes are downgoing bilaterally. (cdc.gov)
  • Cognitive control of micturition is achieved by communication from a number of brain structures to the periaqueductal gray matter, which then exerts control over the pontine micturition center to suppress or trigger a voiding reflex. (medscape.com)
  • Higher brain centers then determine whether it is socially acceptable to void and trigger downstream structures to permit or suppress the voiding reflex. (medscape.com)
  • Subjects with urine mercury levels above 0.6 milligrams/liter demonstrated slightly poorer performance than the remaining subjects including decreased strength, decreased coordination, increased tremor, decreased sensation, and increased prevalence of Babinski and snout reflexes which were consistent with small, subclinical central and peripheral nervous system adverse effects. (cdc.gov)
  • While first described in the medical literature by Babinski in 1896, the reflex has been identified in art at least as early as Botticelli's Virgin and Child with an Angel, painted in the mid-15th century. (wikipedia.org)
  • There are several other reflexes you may notice in a newborn baby. (healthline.com)
  • If a baby's mouth opens and accepts the spoon, the reflex may be fading or is already gone. (healthline.com)
  • To test this reflex, stroke the corner of your baby's mouth or cheek. (nestedbean.com)
  • While we are looking down at our sweet bundle with love hearts popping all over our heads, the baby is displaying their palmar grasp or grasp reflex. (nestedbean.com)
  • Since these newborn reflexes are innate and involuntary, they gradually disappear as the baby matures. (thoughtfulparent.com)
  • This reflex works together with the sucking reflex , which develops between 32 and 36 weeks of gestation. (healthline.com)
  • The Babinski reflex occurs after the sole of the foot has been firmly stroked. (medlineplus.gov)
  • Absence of this reflex occurs in blindness and in injuries to cranial nerves III, V, and VII. (unboundmedicine.com)
  • This reflex occurs when the baby is held upright with their feet touching a hard surface. (nestedbean.com)
  • Stepping reflex - When feet touching flat surface and infant help upright, they move legs as if to walk. (freezingblue.com)
  • When, in fact, the baby is just showing off her stepping reflex. (nestedbean.com)
  • the finger flexor reflex is a simple monosynaptic spinal reflex involving the flexor digitorum profundus that is normally fully inhibited by upper motor neurons. (wikipedia.org)
  • Normal voiding is essentially a spinal reflex modulated by the central nervous system (brain and spinal cord), which coordinates function of the bladder and urethra. (medscape.com)
  • In healthy adults, the plantar reflex causes a downward response of the hallux (flexion). (wikipedia.org)
  • The Babinski response is also normal while asleep and after a long period of walking. (wikipedia.org)
  • He has an equivocal left Babinski response with downgoing toes on the right. (medscape.com)
  • Any reflex involving the response of a visceral effector (cardiac muscle, smooth muscle, or gland). (unboundmedicine.com)
  • One of your baby's first reflexes develops is tonic neck or more commonly known as the fencing reflex. (nestedbean.com)
  • While adjustments do impact the nervous system, it is due to the stretch reflex (Clark). (crabbychiropractic.com)
  • A reflex elicited by quick, vigorous dorsiflexion of the foot while the knee is held in a flexed position, resulting in repeated clonic movement of the foot as long as it is maintained in dorsiflexion. (unboundmedicine.com)
  • These reflexes disappear or are inhibited by the frontal lobes as a child moves through normal child development. (bionity.com)
  • Reflexes may also be limited to those areas affected by the atypical neurology, such as individuals whose cerebral palsy affects only their legs retaining the Babinski reflex but having normal speech. (bionity.com)
  • As a result of dependence upon higher brain centers, certain lesions or diseases of the brain (eg, stroke, cancer, dementia) can result in a loss of voluntary control of the normal micturition reflex as well as symptoms such as urinary urgency. (medscape.com)