The spinal or vertebral column.
A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.
Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)
Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.
A set of twelve curved bones which connect to the vertebral column posteriorly, and terminate anteriorly as costal cartilage. Together, they form a protective cage around the internal thoracic organs.
Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures.
The anterior concavity in the curvature of the lumbar and cervical spine as viewed from the side. The term usually refers to abnormally increased curvature (hollow back, saddle back, swayback). It does not include lordosis as normal mating posture in certain animals ( = POSTURE + SEX BEHAVIOR, ANIMAL).
Internal devices used in osteosynthesis to hold the position of the fracture in proper alignment. By applying the principles of biomedical engineering, the surgeon uses metal plates, nails, rods, etc., for the correction of skeletal defects.
VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.
Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by dense, gliogenous tissue and may be associated with SPINAL CORD NEOPLASMS; spinal cord traumatic injuries; and vascular malformations. Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). Lower extremity spasticity and incontinence may also develop. (From Adams et al., Principles of Neurology, 6th ed, p1269)
Procedures used to treat and correct deformities, diseases, and injuries to the MUSCULOSKELETAL SYSTEM, its articulations, and associated structures.
Surgical removal of ribs, allowing the chest wall to move inward and collapse a diseased lung. (Dorland, 28th ed)
Deformities of the SPINE characterized by abnormal bending or flexure in the vertebral column. They may be bending forward (KYPHOSIS), backward (LORDOSIS), or sideway (SCOLIOSIS).
A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
The pull on a limb or a part thereof. Skin traction (indirect traction) is applied by using a bandage to pull on the skin and fascia where light traction is required. Skeletal traction (direct traction), however, uses pins or wires inserted through bone and is attached to weights, pulleys, and ropes. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed)
The space or compartment surrounded by the pelvic girdle (bony pelvis). It is subdivided into the greater pelvis and LESSER PELVIS. The pelvic girdle is formed by the PELVIC BONES and SACRUM.
A group of congenital malformations involving the brainstem, cerebellum, upper spinal cord, and surrounding bony structures. Type II is the most common, and features compression of the medulla and cerebellar tonsils into the upper cervical spinal canal and an associated MENINGOMYELOCELE. Type I features similar, but less severe malformations and is without an associated meningomyelocele. Type III has the features of type II with an additional herniation of the entire cerebellum through the bony defect involving the foramen magnum, forming an ENCEPHALOCELE. Type IV is a form a cerebellar hypoplasia. Clinical manifestations of types I-III include TORTICOLLIS; opisthotonus; HEADACHE; VERTIGO; VOCAL CORD PARALYSIS; APNEA; NYSTAGMUS, CONGENITAL; swallowing difficulties; and ATAXIA. (From Menkes, Textbook of Child Neurology, 5th ed, p261; Davis, Textbook of Neuropathology, 2nd ed, pp236-46)
A type of juvenile osteochondrosis affecting the fibrocartilaginous disc (INTERVERTEBRAL DISC) in the thoracic or thoracolumbar region of the SPINE. It is characterized by a forward concave SPINAL CURVATURE or KYPHOSIS.
The rear surface of an upright primate from the shoulders to the hip, or the dorsal surface of tetrapods.
Making measurements by the use of stereoscopic photographs.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Any of the 23 plates of fibrocartilage found between the bodies of adjacent VERTEBRAE.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The position or attitude of the body.
Examination of any part of the body for diagnostic purposes by means of X-RAYS or GAMMA RAYS, recording the image on a sensitized surface (such as photographic film).
Motion of an object in which either one or more points on a line are fixed. It is also the motion of a particle about a fixed point. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A method of three-dimensional morphometry in which contour maps are produced from the overlapping interference fringes created when an object is illuminated by beams of coherent light issuing from two different point sources.
Congenital or postnatal overgrowth syndrome most often in height and occipitofrontal circumference with variable delayed motor and cognitive development. Other associated features include advanced bone age, seizures, NEONATAL JAUNDICE; HYPOTONIA; and SCOLIOSIS. It is also associated with increased risk of developing neoplasms in adulthood. Mutations in the NSD1 protein and its HAPLOINSUFFICIENCY are associated with the syndrome.
Apparatus used to support, align, prevent, or correct deformities or to improve the function of movable parts of the body.
Bones that constitute each half of the pelvic girdle in VERTEBRATES, formed by fusion of the ILIUM; ISCHIUM; and PUBIC BONE.
A pathologic entity characterized by deossification of a weight-bearing long bone, followed by bending and pathologic fracture, with inability to form normal BONY CALLUS leading to existence of the "false joint" that gives the condition its name. (Dorland, 27th ed)
Surgical incision into the chest wall.
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.
Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240)
The upper part of the trunk between the NECK and the ABDOMEN. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)
Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Five fused VERTEBRAE forming a triangle-shaped structure at the back of the PELVIS. It articulates superiorly with the LUMBAR VERTEBRAE, inferiorly with the COCCYX, and anteriorly with the ILIUM of the PELVIS. The sacrum strengthens and stabilizes the PELVIS.
'Spinal diseases' is a broad term referring to various medical conditions that affect the structural integrity, function, or health of the spinal column, including degenerative disorders, infections, inflammatory processes, traumatic injuries, neoplasms, and congenital abnormalities.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Region of the back including the LUMBAR VERTEBRAE, SACRUM, and nearby structures.
Congenital structural abnormalities and deformities of the musculoskeletal system.
Disorders affecting the organs of the thorax.
A melatonin receptor subtype primarily found expressed in the BRAIN and RETINA.
Steel wires, often threaded through the skin, soft tissues, and bone, used to fix broken bones. Kirschner wires or apparatus also includes the application of traction to the healing bones through the wires.
Forward displacement of a superior vertebral body over the vertebral body below.
Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)
Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. (From Joynt, Clinical Neurology, 1992, Ch55, p34)
Dressings made of fiberglass, plastic, or bandage impregnated with plaster of paris used for immobilization of various parts of the body in cases of fractures, dislocations, and infected wounds. In comparison with plaster casts, casts made of fiberglass or plastic are lightweight, radiolucent, able to withstand moisture, and less rigid.
The constant checking on the state or condition of a patient during the course of a surgical operation (e.g., checking of vital signs).
A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.
X-ray visualization of the chest and organs of the thoracic cavity. It is not restricted to visualization of the lungs.
'Abnormalities, Multiple' is a broad term referring to the presence of two or more structural or functional anomalies in an individual, which may be genetic or environmental in origin, and can affect various systems and organs of the body.
Conjoined twins are a rare type of monozygotic twinning where genetically identical individuals form a single organism with varying degrees of physical connection and shared anatomy due to incomplete division during embryonic development.
A disease of bone marked by thinning of the cortex by fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC).
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
An abnormal twisting or rotation of a bodily part or member on its axis.
Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
A light-sensitive neuroendocrine organ attached to the roof of the THIRD VENTRICLE of the brain. The pineal gland secretes MELATONIN, other BIOGENIC AMINES and NEUROPEPTIDES.
A rare genetic disorder characterized by partial or complete absence of the CORPUS CALLOSUM, resulting in infantile spasms, MENTAL RETARDATION, and lesions of the RETINA or OPTIC NERVE.
The volume of air that is exhaled by a maximal expiration following a maximal inspiration.
The outer margins of the thorax containing SKIN, deep FASCIA; THORACIC VERTEBRAE; RIBS; STERNUM; and MUSCLES.
A POSTURE in which an ideal body mass distribution is achieved. Postural balance provides the body carriage stability and conditions for normal functions in stationary position or in movement, such as sitting, standing, or walking.
A surgical specialty which utilizes medical, surgical, and physical methods to treat and correct deformities, diseases, and injuries to the skeletal system, its articulations, and associated structures.
The period of care beginning when the patient is removed from surgery and aimed at meeting the patient's psychological and physical needs directly after surgery. (From Dictionary of Health Services Management, 2d ed)
The cavity within the SPINAL COLUMN through which the SPINAL CORD passes.
Deep muscles in the BACK whose function is to extend and rotate the SPINE and maintain POSTURE. It consists splenius, semispinalis, multifidus, rotatores, interspinales, intertransversarii and sacrospinalis.
An outward slant of the thigh in which the knees are wide apart and the ankles close together. Genu varum can develop due to skeletal and joint dysplasia (e.g., OSTEOARTHRITIS; Blount's disease); and malnutrition (e.g., RICKETS; FLUORIDE POISONING).
Endoscopic surgery of the pleural cavity performed with visualization via video transmission.
Excision, in part or whole, of an INTERVERTEBRAL DISC. The most common indication is disk displacement or herniation. In addition to standard surgical removal, it can be performed by percutaneous diskectomy (DISKECTOMY, PERCUTANEOUS) or by laparoscopic diskectomy, the former being the more common.
Intraoperative computer-assisted 3D navigation and guidance system generally used in neurosurgery for tracking surgical tools and localize them with respect to the patient's 3D anatomy. The pre-operative diagnostic scan is used as a reference and is transferred onto the operative field during surgery.
Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates.
Reference points located by visual inspection, palpation, or computer assistance, that are useful in localizing structures on or within the human body.
Measurements of the height, weight, length, area, etc., of the human and animal body or its parts.
Manner or style of walking.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
The distance and direction to which a bone joint can be extended. Range of motion is a function of the condition of the joints, muscles, and connective tissues involved. Joint flexibility can be improved through appropriate MUSCLE STRETCHING EXERCISES.
The medial terminal branch of the sciatic nerve. The tibial nerve fibers originate in lumbar and sacral spinal segments (L4 to S2). They supply motor and sensory innervation to parts of the calf and foot.
A characteristic symptom complex.
A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)
Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.
A developmental anomaly in which the lower sternum is posteriorly dislocated and concavely deformed, resulting in a funnel-shaped thorax.
Diagnosis of disease states by recording the spontaneous electrical activity of tissues or organs or by the response to stimulation of electrically excitable tissue.
The physical state of supporting an applied load. This often refers to the weight-bearing bones or joints that support the body's weight, especially those in the spine, hip, knee, and foot.
The continuous sequential physiological and psychological changes during ADOLESCENCE, approximately between the age of 13 and 18.
Surgery performed on the thoracic organs, most commonly the lungs and the heart.
A condition in which one of a pair of legs fails to grow as long as the other, which could result from injury or surgery.
Paralysis of one or more of the ocular muscles due to disorders of the eye muscles, neuromuscular junction, supporting soft tissue, tendons, or innervation to the muscles.
Methods of creating machines and devices.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
A condition of persistent pain and discomfort in the BACK and the LEG following lumbar surgery, often seen in patients enrolled in pain centers.
Nonexpendable items used in the performance of orthopedic surgery and related therapy. They are differentiated from ORTHOTIC DEVICES, apparatus used to prevent or correct deformities in patients.
Congenital abnormality characterized by the lack of full development of the ESOPHAGUS that commonly occurs with TRACHEOESOPHAGEAL FISTULA. Symptoms include excessive SALIVATION; GAGGING; CYANOSIS; and DYSPNEA.
The grafting of bone from a donor site to a recipient site.
Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.
The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Loss of blood during a surgical procedure.
Failure of equipment to perform to standard. The failure may be due to defects or improper use.
An INTERVERTEBRAL DISC in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.
A departure from the normal gait in animals.
Nonexpendable apparatus used during surgical procedures. They are differentiated from SURGICAL INSTRUMENTS, usually hand-held and used in the immediate operative field.
A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.
Measure of the maximum amount of air that can be breathed in and blown out over a sustained interval such as 15 or 20 seconds. Common abbreviations are MVV and MBC.
Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.
The central part of the body to which the neck and limbs are attached.
Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.
Surgery performed on the nervous system or its parts.
Graphic displays of height and weight showing development over time.
Defective bone formation involving individual bones, singly or in combination.
An abnormal response to a stimulus applied to the sensory components of the nervous system. This may take the form of increased, decreased, or absent reflexes.
Persistent flexure or contracture of a joint.
The surgical fixation of a joint by a procedure designed to accomplish fusion of the joint surfaces by promoting the proliferation of bone cells. (Dorland, 28th ed)
Contractions of the abdominal muscles upon stimulation of the skin (superficial abdominal reflex) or tapping neighboring bony structures (deep abdominal reflex). The superficial reflex may be weak or absent, for example, after a stroke, a sign of upper (suprasegmental) motor neuron lesions. (Stedman, 25th ed & Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p1073)
A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
The projecting part on each side of the body, formed by the side of the pelvis and the top portion of the femur.
An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
Control of bleeding during or after surgery.
I'm sorry for any confusion, but "Poland" is not a medical term or concept; it is a country located in Central Europe. If you have any questions about medical topics or definitions, I would be happy to help answer those!
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Abnormal passage between the ESOPHAGUS and the TRACHEA, acquired or congenital, often associated with ESOPHAGEAL ATRESIA.
COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.
A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.
Part of the body in humans and primates where the arms connect to the trunk. The shoulder has five joints; ACROMIOCLAVICULAR joint, CORACOCLAVICULAR joint, GLENOHUMERAL joint, scapulathoracic joint, and STERNOCLAVICULAR joint.
Developmental bone diseases are a category of skeletal disorders that arise from disturbances in the normal growth and development of bones, including abnormalities in size, shape, structure, or composition, which can lead to various musculoskeletal impairments and deformities.
I'm sorry for any confusion, but "Utah" is a proper noun and refers to a state in the United States, it does not have a medical definition. If you have any medical questions or need information on specific medical conditions or terms, I would be happy to help!
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
The period following a surgical operation.
Excision of part of the skull. This procedure is used to treat elevated intracranial pressure that is unresponsive to conventional treatment.
Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Preventive health services provided for students. It excludes college or university students.
Narrowing of the spinal canal.
The largest of three bones that make up each half of the pelvic girdle.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
The degree to which the individual regards the health care service or product or the manner in which it is delivered by the provider as useful, effective, or beneficial.
Spinal neoplasms are abnormal growths or tumors that develop within the spinal column, which can be benign or malignant, and originate from cells within the spinal structure or spread to the spine from other parts of the body (metastatic).
Elements of limited time intervals, contributing to particular results or situations.
Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.
The magnitude of INBREEDING in humans.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Computer systems or networks designed to provide radiographic interpretive information.
A genus of livebearing cyprinodont fish comprising the guppy and molly. Some species are virtually all female and depend on sperm from other species to stimulate egg development. Poecilia is used in carcinogenicity studies as well as neurologic and physiologic research.
The course of learning of an individual or a group. It is a measure of performance plotted over time.
Measurement of distances or movements by means of the phenomena caused by the interference of two rays of light (optical interferometry) or of sound (acoustic interferometry).
Injection of BONE CEMENTS into bone to treat bone lesions.
The period during a surgical operation.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
Benign circumscribed tumor of spongy bone occurring especially in the bones of the extremities and vertebrae, most often in young persons. (Dorland, 27th ed)
Congenital or acquired asymmetry of the face.
Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.
Two off-spring from the same PREGNANCY. They are from a single fertilized OVUM that split into two EMBRYOS. Such twins are usually genetically identical and of the same sex.
I'm sorry for any confusion, but "Kentucky" is a proper noun and not a term that has a medical definition. It is a state located in the eastern region of the United States. If you have any questions related to medical conditions or terminology, I would be happy to help answer those!
Disorders affecting TWINS, one or both, at any age.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The use of two or more chemicals simultaneously or sequentially to induce anesthesia. The drugs need not be in the same dosage form.
A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.
A family composed of spouses and their children.
Procedures used to reconstruct, restore, or improve defective, damaged, or missing structures.
A deformed foot in which the foot is plantarflexed, inverted and adducted.
The inferior part of the lower extremity between the KNEE and the ANKLE.
"Dislocation is a traumatic injury wherein the normal articulation between two bones at a joint is disrupted, resulting in the complete separation of the bone ends and associated soft tissues from their usual position."
A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.
Therapeutic modalities frequently used in PHYSICAL THERAPY SPECIALTY by PHYSICAL THERAPISTS or physiotherapists to promote, maintain, or restore the physical and physiological well-being of an individual.
External devices which hold wires or pins that are placed through one or both cortices of bone in order to hold the position of a fracture in proper alignment. These devices allow easy access to wounds, adjustment during the course of healing, and more functional use of the limbs involved.
A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is significantly below the average height.
The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
The period before a surgical operation.
Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.
Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)
Individuals' concept of their own bodies.
Malformations of organs or body parts during development in utero.
Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure).
An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.
A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.
The neck muscles consist of the platysma, splenius cervicis, sternocleidomastoid(eus), longus colli, the anterior, medius, and posterior scalenes, digastric(us), stylohyoid(eus), mylohyoid(eus), geniohyoid(eus), sternohyoid(eus), omohyoid(eus), sternothyroid(eus), and thyrohyoid(eus).
Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
Antifibrinolytic hemostatic used in severe hemorrhage.
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Reinfusion of blood or blood products derived from the patient's own circulation. (Dorland, 27th ed)
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Townes-Brocks syndrome. (1/1119)

Townes-Brocks syndrome (TBS) is an autosomal dominant disorder with multiple malformations and variable expression. Major findings include external ear anomalies, hearing loss, preaxial polydactyly and triphalangeal thumbs, imperforate anus, and renal malformations. Most patients with Townes-Brocks syndrome have normal intelligence, although mental retardation has been noted in a few.  (+info)

Hyper-IgE syndrome with recurrent infections--an autosomal dominant multisystem disorder. (2/1119)

BACKGROUND: The hyper-IgE syndrome with recurrent infections is a rare immunodeficiency characterized by recurrent skin and pulmonary abscesses and extremely elevated levels of IgE in serum. Associated facial and skeletal features have been recognized, but their frequency is unknown, and the genetic basis of the hyper-IgE syndrome is poorly understood. METHODS: We studied 30 patients with the hyper-IgE syndrome and 70 of their relatives. We took histories, reviewed records, performed physical and dental examinations, took anthropometric measurements, and conducted laboratory studies. RESULTS: Nonimmunologic features of the hyper-IgE syndrome were present in all patients older than eight years. Seventy-two percent had the previously unrecognized feature of failure or delay of shedding of the primary teeth owing to lack of root resorption. Common findings among patients were recurrent fractures (in 57 percent of patients), hyperextensible joints (in 68 percent), and scoliosis (in 76 percent of patients 16 years of age or older). The classic triad of abscesses, pneumonia, and an elevated IgE level was identified in 77 percent of all patients and in 85 percent of those older than eight. In 6 of 23 adults (26 percent), IgE levels declined over time and came closer to or fell within the normal range. Autosomal dominant transmission of the hyper-IgE syndrome was found, but with variable expressivity. Of the 27 relatives at risk for inheriting the hyper-IgE syndrome, 10 were fully affected, 11 were unaffected, and 6 had combinations of mild immunologic, dental, and skeletal features of the hyper-IgE syndrome. CONCLUSIONS: The hyper-IgE syndrome is a multisystem disorder that affects the dentition, the skeleton, connective tissue, and the immune system. It is inherited as a single-locus autosomal dominant trait with variable expressivity.  (+info)

The immediate effect of a Boston brace on lung volumes and pulmonary compliance in mild adolescent idiopathic scoliosis. (3/1119)

Idiopathic scoliosis (IS) is known to result in lung volume and pulmonary compliance reduction. Boston brace treatment of IS is an additional factor causing restrictive respiratory syndrome due to external chest wall compression. Nevertheless, the immediate effect of Boston bracing on the pulmonary compliance of scoliotic patients has not been studied systematically. Spirometric and plethysmographic lung volumes, static lung compliance (C(ST)(L)) and specific lung compliance (C(ST)(L)/functional residual capacity) of 15 scoliotic adolescents (14 females and 1 male, of mean age 14.1+/-1.67 years, with mean Cobb angle 24.1 degrees+/-7.88 degrees) were recorded twice, in a random sequence: once without the Boston brace (nBB) and once immediately after wearing the brace (BB). Our findings showed that bracing reduced vital capacity, residual volume, functional residual capacity (FRC), total lung capacity, and forced expiratory volume in 1s in a proportional and significant way (P < 0.001). C(ST)(L) was also significantly reduced (P < 0.001), but C(ST)(L)/FRC remained unaltered. All BB and nBB indices were highly correlated. We concluded that Boston bracing in IS patients results in an immediate, predictable, and uniform reduction of lung volumes and pulmonary compliance. The reduction of C(ST)(L) under bracing conditions was related to the decrease of lung volume; the C(ST)(L)/FRC remained unaltered.  (+info)

Cotrel-Dubousset instrumentation for the treatment of severe scoliosis. (4/1119)

In a multicentric study, 36 cases (40 curves) of severe scoliosis were analysed; 19 were idiopathic and 17 neurological, Cobb angles ranged from 70 degrees to 145 degrees, all had undergone three-rod Cotrel-Dubousset (CD) instrumentation. The correction on the frontal plane achieved more than 50% of the preoperative angle (53.9% for idiopathic curves and 55.6% for neurological ones). On the sagittal plane the pathological shape of the spine was reduced and distinctly ameliorated. In ten patients, the authors successfully applied a technique, alternative to the original one, which was based on the use of two or three screws in the lumbar area, one supplementary pedicle transverse claw on the cranial area and two rods connected by a domino, instead of a single rod (the longer one applied on the concave side). The main complications were: one case of infection, three of vascular compression of the duodenum, one of crank-shaft phenomenon and one laminar hook displacement. The excellent result achieved in both, idiopathic and neurological severe and stiff scoliosis shows the efficacy, reliability and versatility of CD three-rod instrumentation.  (+info)

Long-term three-dimensional changes of the spine after posterior spinal instrumentation and fusion in adolescent idiopathic scoliosis. (5/1119)

This is a prospective study comparing the short- and long-term three-dimensional (3D) changes in shape, length and balance of the spine after spinal instrumentation and fusion in a group of adolescents with idiopathic scoliosis. The objective of the study was to evaluate the stability over time of the postoperative changes of the spine after instrumentation with multi rod, hook and screw instrumentation systems. Thirty adolescents (average age: 14.5+/-1.6 years) undergoing surgery by a posterior approach had computerized 3D reconstructions of the spine done at an average of 3 days preoperatively (stage I), and 2 months (stage II) and 2,5 years (stage III) after surgery, using a digital multi-planar radiographic technique. Stages I, II and III were compared using various geometrical parameters of spinal length, curve severity, and orientation. Significant improvement of curve magnitude between stages I and II was documented in the frontal plane for thoracic and lumbar curves, as well as in the orientation of the plane of maximum deformity, which was significantly shifted towards the sagittal plane in thoracic curves. However, there was a significant loss of this correction between stages II and III. Slight changes were noted in apical vertebral rotation, in thoracic kyphosis and in lumbar lordosis. Spinal length and height were significantly increased at stage II, but at long-term follow-up spinal length continued to increase while spinal height remained similar. These results indicate that although a significant 3D correction can be obtained after posterior instrumentation and fusion, a significant loss of correction and an increase in spinal length occur in the years following surgery, suggesting that a crankshaft phenomenon may be an important factor altering the long-term 3D correction after posterior instrumentation of the spine for idiopathic scoliosis.  (+info)

Complications of scoliosis surgery in children with myelomeningocele. (6/1119)

The purpose of the present study was to evaluate whether the high incidence of complications in scoliosis surgery in myelomeningocele (MMC) could be attributed to the surgical technique and whether improvements were possible. Between 1984 and 1996, 77 patients with MMC and scoliosis were treated surgically. The clinical and radiological follow-up ranged from 1 to 10 years with a mean follow-up of 3.6 years. The mean age at time of surgery was 12 years 8 months. The average preoperative scoliosis measured 90.20 degrees and was corrected by 47%. The first four patients were stabilized with Harrington rods after anterior correction with a Zielke device (group 1). Twenty-five patients were operated only from posterior, using Cotrel-Dubousset (CD) instrumentation (group 2). In 13 patients an anterior release and discectomy was performed prior to CD posterior instrumentation (group 3). In 26 patients (group 4) this was combined with an anterior instrumentation. The 9 patients of group 5 had congenital vertebral malformations which made a special treatment necessary. Complications could be divided into hardware problems, such as implant failure, dislocation or pseudarthrosis, infections, anesthetic, and neurologic complications. Hardware problems were seen in 29% of all patients. More hardware problems were seen with the Harrington rod (75%) and after solitary posterior instrumentation (30%). The occurrence of pseudarthrosis was dependent on the surgical technique, the extent of posterior spondylodesis, and lumbosacral fusion. Patients with hardware problems had a mean loss of correction of 49% compared to 13% in the other patients. Depending on the different surgical techniques a loss of more than 30% was seen in 12-75% of the cases. Early postoperative shunt failure occurred in four cases; delayed failure - after more than 1 year - in three cases. One patient died within 1 day due to an acute hydrocephalus, another died after 2 1/2 years because of chronic shunt insufficiency with herniation. Wound problems were not dependent on the surgical technique, but on the extent of posterior spondylodesis and the lumbosacral fusion. Based on this analysis we believe our current practice of instrumented anterior and posterior fusion is justified. Further, we are very careful to check shunt function prior to acute correction of spinal deformity.  (+info)

Prenatal sonographic features of spondylocostal dysostosis and diaphragmatic hernia in the first trimester. (7/1119)

Spondylocostal dysostosis is a congenital disorder characterized by multiple malformations of the vertebrae and ribs. We describe the sonographic features of an affected fetus at 12 and 14 weeks of gestation. The fetus had thoracic scoliosis, multiple vertebral and rib malformations and a grossly dilated stomach that had herniated into the chest through a left-sided diaphragmatic hernia. The stomach spanned the whole length of the fetal trunk.  (+info)

Complement activation and increased systemic and pulmonary vascular resistance indices during infusion of postoperatively drained untreated blood. (8/1119)

In nine healthy young patients, operated on for thoracic scoliosis, a pulmonary artery catheter was inserted for the study of haemodynamic variables and blood sampling during autologous transfusion of postoperatively drained blood. At 1-3 h after wound closure, 10 ml kg/body weight of drained untreated blood from the wound was collected and recirculated over a l-h period. The concentration of the complement activation product, C3bc, increased from a mean of 5.4 (SD 1.5) AU ml-1 before infusion to 11.1 (3.9) AU ml-1 during infusion and then returned to 7.8 (2.8) AU ml-1 after infusion. The concentration of the terminal complement complex (TCC) increased from 0.5 (0.2) to 1.3 (0.5) AU ml-1 and was reduced to 0.7 (0.3) AU ml-1 after infusion. Only TCC exceeded the reference values which are 14 AU ml-1 for C3bc and 1.0 AU ml-1 for TCC. Pulmonary vascular resistance index concomitantly increased from a mean of 130 (SD 52) to 195 (88) dyn s cm-5 m-2 and was reduced to 170 (86) dyn s cm-5 m-2 after infusion. Systemic vascular resistance index increased from a mean of 1238 (SD 403) to 1349 (473) dyn s cm-5 m-2 and returned to 1196 (401) dyn s cm-5 m-2 after infusion. White blood cell count (WCC) increased from 14.4 (4.3) x 10(9) litre-1 before infusion to 17.8 (7.2) x 10(9) litre-1 during and after infusion. No change in platelet count during infusion was observed. There were no differences in WCC or platelet count between mixed venous or peripheral arterial blood. Pulmonary and systemic vascular resistance indices may be influenced by activated complement in drained untreated blood when it is recirculated.  (+info)

The spine, also known as the vertebral column, is a complex structure in the human body that is part of the axial skeleton. It is composed of 33 individual vertebrae (except in some people where there are fewer due to fusion of certain vertebrae), intervertebral discs, facet joints, ligaments, muscles, and nerves.

The spine has several important functions:

1. Protection: The spine protects the spinal cord, which is a major component of the nervous system, by enclosing it within a bony canal.
2. Support: The spine supports the head and upper body, allowing us to maintain an upright posture and facilitating movement of the trunk and head.
3. Movement: The spine enables various movements such as flexion (bending forward), extension (bending backward), lateral flexion (bending sideways), and rotation (twisting).
4. Weight-bearing: The spine helps distribute weight and pressure evenly across the body, reducing stress on individual vertebrae and other structures.
5. Blood vessel and nerve protection: The spine protects vital blood vessels and nerves that pass through it, including the aorta, vena cava, and spinal nerves.

The spine is divided into five regions: cervical (7 vertebrae), thoracic (12 vertebrae), lumbar (5 vertebrae), sacrum (5 fused vertebrae), and coccyx (4 fused vertebrae, also known as the tailbone). Each region has unique characteristics that allow for specific functions and adaptations to the body's needs.

The thoracic vertebrae are the 12 vertebrae in the thoracic region of the spine, which is the portion between the cervical and lumbar regions. These vertebrae are numbered T1 to T12, with T1 being closest to the skull and T12 connecting to the lumbar region.

The main function of the thoracic vertebrae is to provide stability and support for the chest region, including protection for the vital organs within, such as the heart and lungs. Each thoracic vertebra has costal facets on its sides, which articulate with the heads of the ribs, forming the costovertebral joints. This connection between the spine and the ribcage allows for a range of movements while maintaining stability.

The thoracic vertebrae have a unique structure compared to other regions of the spine. They are characterized by having long, narrow bodies, small bony processes, and prominent spinous processes that point downwards. This particular shape and orientation of the thoracic vertebrae contribute to their role in limiting excessive spinal movement and providing overall trunk stability.

Spinal fusion is a surgical procedure where two or more vertebrae in the spine are fused together to create a solid bone. The purpose of this procedure is to restrict movement between the fused vertebrae, which can help reduce pain and stabilize the spine. This is typically done using bone grafts or bone graft substitutes, along with hardware such as rods, screws, or cages to hold the vertebrae in place while they heal together. The procedure may be recommended for various spinal conditions, including degenerative disc disease, spinal stenosis, spondylolisthesis, scoliosis, or fractures.

Kyphosis is a medical term used to describe an excessive curvature of the spine in the sagittal plane, leading to a rounded or humped back appearance. This condition often affects the thoracic region of the spine and can result from various factors such as age-related degenerative changes, congenital disorders, Scheuermann's disease, osteoporosis, or traumatic injuries. Mild kyphosis may not cause any significant symptoms; however, severe cases can lead to pain, respiratory difficulties, and decreased quality of life. Treatment options typically include physical therapy, bracing, and, in some cases, surgical intervention.

In medical terms, ribs are the long, curved bones that make up the ribcage in the human body. They articulate with the thoracic vertebrae posteriorly and connect to the sternum anteriorly via costal cartilages. There are 12 pairs of ribs in total, and they play a crucial role in protecting the lungs and heart, allowing room for expansion and contraction during breathing. Ribs also provide attachment points for various muscles involved in respiration and posture.

Bone screws are medical devices used in orthopedic and trauma surgery to affix bone fracture fragments or to attach bones to other bones or to metal implants such as plates, rods, or artificial joints. They are typically made of stainless steel or titanium alloys and have a threaded shaft that allows for purchase in the bone when tightened. The head of the screw may have a hexagonal or star-shaped design to allow for precise tightening with a screwdriver. Bone screws come in various shapes, sizes, and designs, including fully threaded, partially threaded, cannulated (hollow), and headless types, depending on their intended use and location in the body.

Lordosis is a term used in the medical field to describe an excessive inward curvature of the spine. It most commonly occurs in the cervical (neck) and lumbar (lower back) regions. When it happens in the lower back, it's often referred to as swayback. While some degree of lordosis is normal and necessary for proper spinal alignment and movement, excessive curvature can lead to pain, discomfort, and difficulty with mobility. It can be caused by a variety of factors, including poor posture, obesity, pregnancy, and certain medical conditions such as kyphosis or spondylolisthesis.

Internal fixators are medical devices that are implanted into the body through surgery to stabilize and hold broken or fractured bones in the correct position while they heal. These devices can be made from various materials, such as metal (stainless steel or titanium) or bioabsorbable materials. Internal fixators can take many forms, including plates, screws, rods, nails, wires, or cages, depending on the type and location of the fracture.

The main goal of using internal fixators is to promote bone healing by maintaining accurate reduction and alignment of the fractured bones, allowing for early mobilization and rehabilitation. This can help reduce the risk of complications such as malunion, nonunion, or deformity. Internal fixators are typically removed once the bone has healed, although some bioabsorbable devices may not require a second surgery for removal.

It is important to note that while internal fixators provide stability and support for fractured bones, they do not replace the need for proper immobilization, protection, or rehabilitation during the healing process. Close follow-up with an orthopedic surgeon is essential to ensure appropriate healing and address any potential complications.

The lumbar vertebrae are the five largest and strongest vertebrae in the human spine, located in the lower back region. They are responsible for bearing most of the body's weight and providing stability during movement. The lumbar vertebrae have a characteristic shape, with a large body in the front, which serves as the main weight-bearing structure, and a bony ring in the back, formed by the pedicles, laminae, and processes. This ring encloses and protects the spinal cord and nerves. The lumbar vertebrae are numbered L1 to L5, starting from the uppermost one. They allow for flexion, extension, lateral bending, and rotation movements of the trunk.

Syringomyelia is a medical condition characterized by the formation of a fluid-filled cavity or cavities (syrinx) within the spinal cord. This syrinx can lead to various symptoms depending on its size and location, which may include pain, muscle weakness, numbness, and stiffness in the neck, back, shoulders, arms, or legs. In some cases, it may also affect bladder and bowel function, sexual performance, and the ability to maintain normal body temperature. Syringomyelia is often associated with Chiari malformation, a condition where the lower part of the brain extends into the spinal canal. However, other conditions such as spinal cord injuries, tumors, or infections may also cause syringomyelia.

Orthopedic procedures are surgical or nonsurgical methods used to treat musculoskeletal conditions, including injuries, deformities, or diseases of the bones, joints, muscles, ligaments, and tendons. These procedures can range from simple splinting or casting to complex surgeries such as joint replacements, spinal fusions, or osteotomies (cutting and repositioning bones). The primary goal of orthopedic procedures is to restore function, reduce pain, and improve the quality of life for patients.

Thoracoplasty is a surgical procedure that involves the removal or collapse of one or more ribs and the attached muscles from the chest wall. This procedure is typically performed to correct a deformity or to remove infected tissue in the chest cavity, such as in cases of chronic empyema (a collection of pus in the pleural space) or tuberculosis.

The removal of ribs can also help to reduce the size of an overexpanded lung, which can occur due to conditions like COPD (chronic obstructive pulmonary disease) or a bronchopleural fistula (an abnormal connection between the airways and the pleural space). Thoracoplasty can also be used for cosmetic purposes, such as in the treatment of pectus excavatum (a deformity where the breastbone is sunken into the chest).

Spinal curvatures refer to the normal or abnormal curvature patterns of the spine as viewed from the side. The human spine has four distinct curves that form an "S" shape when viewed from the side: cervical, thoracic, lumbar, and sacral. These natural curves provide strength, flexibility, and balance to the spine, allowing us to stand upright, maintain proper posture, and absorb shock during movement.

Abnormal spinal curvatures are often referred to as spinal deformities and can be classified into two main categories: hyperkyphosis (increased kyphosis) and hyperlordosis (increased lordosis). Examples of such conditions include:

1. Kyphosis: An excessive curvature in the thoracic or sacral regions, leading to a hunchback or rounded appearance. Mild kyphosis is common and usually not problematic, but severe cases can cause pain, breathing difficulties, and neurological issues.
2. Lordosis: An abnormal increase in the curvature of the lumbar or cervical spine, resulting in an exaggerated swayback posture. This can lead to lower back pain, muscle strain, and difficulty maintaining proper balance.
3. Scoliosis: A lateral (side-to-side) spinal curvature that causes the spine to twist and rotate, forming a C or S shape when viewed from behind. Most scoliosis cases are idiopathic (of unknown cause), but they can also be congenital (present at birth) or secondary to other medical conditions.

These abnormal spinal curvatures may require medical intervention, such as physical therapy, bracing, or surgery, depending on the severity and progression of the condition.

Neuromuscular diseases are a group of disorders that involve the peripheral nervous system, which includes the nerves and muscles outside of the brain and spinal cord. These conditions can affect both children and adults, and they can be inherited or acquired. Neuromuscular diseases can cause a wide range of symptoms, including muscle weakness, numbness, tingling, pain, cramping, and twitching. Some common examples of neuromuscular diseases include muscular dystrophy, amyotrophic lateral sclerosis (ALS), peripheral neuropathy, and myasthenia gravis. The specific symptoms and severity of these conditions can vary widely depending on the underlying cause and the specific muscles and nerves that are affected. Treatment for neuromuscular diseases may include medications, physical therapy, assistive devices, or surgery, depending on the individual case.

Traction, in medical terms, refers to the application of a pulling force to distract or align parts of the body, particularly bones, joints, or muscles, with the aim of immobilizing, reducing displacement, or realigning them. This is often achieved through the use of various devices such as tongs, pulleys, weights, or specialized traction tables. Traction may be applied manually or mechanically and can be continuous or intermittent, depending on the specific medical condition being treated. Common indications for traction include fractures, dislocations, spinal cord injuries, and certain neurological conditions.

The pelvis is the lower part of the trunk, located between the abdomen and the lower limbs. It is formed by the fusion of several bones: the ilium, ischium, and pubis (which together form the hip bone on each side), and the sacrum and coccyx in the back. The pelvis has several functions including supporting the weight of the upper body when sitting, protecting the lower abdominal organs, and providing attachment for muscles that enable movement of the lower limbs. In addition, it serves as a bony canal through which the reproductive and digestive tracts pass. The pelvic cavity contains several vital organs such as the bladder, parts of the large intestine, and in females, the uterus, ovaries, and fallopian tubes.

Arnold-Chiari malformation is a structural abnormality of the brain and skull base, specifically the cerebellum and brainstem. It is characterized by the descent of the cerebellar tonsils and sometimes parts of the brainstem through the foramen magnum (the opening at the base of the skull) into the upper spinal canal. This can cause pressure on the brainstem and cerebellum, potentially leading to a range of symptoms such as headaches, neck pain, unsteady gait, swallowing difficulties, hearing or balance problems, and in severe cases, neurological deficits. There are four types of Arnold-Chiari malformations, with type I being the most common and least severe form. Types II, III, and IV are progressively more severe and involve varying degrees of hindbrain herniation and associated neural tissue damage. Surgical intervention is often required to alleviate symptoms and prevent further neurological deterioration.

Scheuermann's Disease, also known as Scheuermann's Kyphosis, is a medical condition that affects the spine. It is a developmental disorder of the vertebral bodies involving anterior wedging of at least three adjacent vertebrae, leading to a progressive rounded or hunchback-like curvature of the upper (thoracic) spine. This deformity can result in a rigid, angular kyphosis and may cause back pain, breathing difficulties, or cosmetic concerns. The exact cause of Scheuermann's Disease is unknown, but it tends to run in families and is more common in males than females. Treatment typically includes physical therapy, bracing, and, in severe cases, surgery.

The term "back" is a common word used to describe the large posterior part of the body of a human or an animal, which extends from the neck to the pelvis and contains the spine, spinal cord, ribs, muscles, and other various tissues. In medical terms, the back is also known as the dorsal region. It provides support, protection, and mobility for the body, allowing us to stand upright, bend, twist, and perform various physical activities. The back is susceptible to various injuries, disorders, and conditions, such as back pain, strains, sprains, herniated discs, scoliosis, and arthritis, among others.

Photogrammetry is not typically considered a medical term, but rather it is a technique used in various fields including engineering, architecture, and geology. However, it has found some applications in the medical field, particularly in orthopedics and wound care. Here's a definition that covers its general use as well as its medical applications:

Photogrammetry is the science of making measurements from photographs, especially for recovering the exact positions of surface points on an object. It involves the use of photography to accurately measure and map three-dimensional objects or environments. In the medical field, photogrammetry can be used to create 3D models of body parts (such as bones or wounds) by capturing multiple images from different angles and then processing them using specialized software. These 3D models can help healthcare professionals plan treatments, monitor progress, and assess outcomes in a more precise manner.

Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.

An intervertebral disc is a fibrocartilaginous structure found between the vertebrae of the spinal column in humans and other animals. It functions as a shock absorber, distributes mechanical stress during weight-bearing activities, and allows for varying degrees of mobility between adjacent vertebrae.

The disc is composed of two parts: the annulus fibrosus, which forms the tough, outer layer; and the nucleus pulposus, which is a gel-like substance in the center that contains proteoglycans and water. The combination of these components provides the disc with its unique ability to distribute forces and allow for movement.

The intervertebral discs are essential for the normal functioning of the spine, providing stability, flexibility, and protection to the spinal cord and nerves. However, they can also be subject to degeneration and injury, which may result in conditions such as herniated discs or degenerative disc disease.

Retrospective studies, also known as retrospective research or looking back studies, are a type of observational study that examines data from the past to draw conclusions about possible causal relationships between risk factors and outcomes. In these studies, researchers analyze existing records, medical charts, or previously collected data to test a hypothesis or answer a specific research question.

Retrospective studies can be useful for generating hypotheses and identifying trends, but they have limitations compared to prospective studies, which follow participants forward in time from exposure to outcome. Retrospective studies are subject to biases such as recall bias, selection bias, and information bias, which can affect the validity of the results. Therefore, retrospective studies should be interpreted with caution and used primarily to generate hypotheses for further testing in prospective studies.

Posture is the position or alignment of body parts supported by the muscles, especially the spine and head in relation to the vertebral column. It can be described as static (related to a stationary position) or dynamic (related to movement). Good posture involves training your body to stand, walk, sit, and lie in positions where the least strain is placed on supporting muscles and ligaments during movement or weight-bearing activities. Poor posture can lead to various health issues such as back pain, neck pain, headaches, and respiratory problems.

Radiography is a diagnostic technique that uses X-rays, gamma rays, or similar types of radiation to produce images of the internal structures of the body. It is a non-invasive procedure that can help healthcare professionals diagnose and monitor a wide range of medical conditions, including bone fractures, tumors, infections, and foreign objects lodged in the body.

During a radiography exam, a patient is positioned between an X-ray machine and a special film or digital detector. The machine emits a beam of radiation that passes through the body and strikes the film or detector, creating a shadow image of the internal structures. Denser tissues, such as bones, block more of the radiation and appear white on the image, while less dense tissues, such as muscles and organs, allow more of the radiation to pass through and appear darker.

Radiography is a valuable tool in modern medicine, but it does involve exposure to ionizing radiation, which can carry some risks. Healthcare professionals take steps to minimize these risks by using the lowest possible dose of radiation necessary to produce a diagnostic image, and by shielding sensitive areas of the body with lead aprons or other protective devices.

In the context of medicine, particularly in anatomy and physiology, "rotation" refers to the movement of a body part around its own axis or the long axis of another structure. This type of motion is three-dimensional and can occur in various planes. A common example of rotation is the movement of the forearm bones (radius and ulna) around each other during pronation and supination, which allows the hand to be turned palm up or down. Another example is the rotation of the head during mastication (chewing), where the mandible moves in a circular motion around the temporomandibular joint.

I'm sorry for any confusion, but "Moire Topography" is not a recognized term in medical literature or anatomy. Moiré refers to a pattern created when two grids or patterns are overlaid, resulting in a new pattern of alternating light and dark lines. This phenomenon can be seen in various fields such as physics, mathematics, and graphic design. However, it is not typically used in the context of medical definitions related to anatomy or pathology. If you have any other questions or need information on a different topic, please let me know!

Sotos Syndrome is a genetic disorder characterized by excessive early growth and developmental delay. It is also known as cerebral gigantism. The symptoms typically include:

1. Large size at birth, with rapid postnatal growth leading to tall stature in early childhood.
2. Developmental delay, often becoming apparent after the first year of life. This may include delayed milestones in sitting, standing, walking, and speaking.
3. Macrocephaly (large head size).
4. Characteristic facial features such as a high forehead, prominent jaw, and wide-spaced eyes.
5. Learning difficulties or intellectual disability, ranging from mild to severe.
6. Increased risk of seizures, particularly in infancy and childhood.
7. Behavioral problems such as ADHD (Attention Deficit Hyperactivity Disorder) or autism spectrum disorders.

The syndrome is caused by mutations in the NSD1 gene, which is located on chromosome 5. This gene provides instructions for making a protein that helps regulate gene expression. In Sotos Syndrome, the mutated NSD1 gene doesn't function properly, leading to overgrowth and developmental delay. The syndrome is usually inherited in an autosomal dominant manner, meaning that only one copy of the altered gene, inherited from either parent, is sufficient to cause the disorder. However, most cases result from new (de novo) mutations in the gene and occur in people with no family history of the disorder.

Orthotic devices are custom-made or prefabricated appliances designed to align, support, prevent deformity, or improve the function of movable body parts. They are frequently used in the treatment of various musculoskeletal disorders, such as foot and ankle conditions, knee problems, spinal alignment issues, and hand or wrist ailments. These devices can be adjustable or non-adjustable and are typically made from materials like plastic, metal, leather, or fabric. They work by redistributing forces across joints, correcting alignment, preventing unwanted movements, or accommodating existing deformities. Examples of orthotic devices include ankle-foot orthoses, knee braces, back braces, wrist splints, and custom-made foot insoles.

The pelvic bones, also known as the hip bones, are a set of three irregularly shaped bones that connect to form the pelvic girdle in the lower part of the human body. They play a crucial role in supporting the spine and protecting the abdominal and pelvic organs.

The pelvic bones consist of three bones:

1. The ilium: This is the largest and uppermost bone, forming the majority of the hip bone and the broad, flaring part of the pelvis known as the wing of the ilium or the iliac crest, which can be felt on the side of the body.
2. The ischium: This is the lower and back portion of the pelvic bone that forms part of the sitting surface or the "sit bones."
3. The pubis: This is the front part of the pelvic bone, which connects to the other side at the pubic symphysis in the midline of the body.

The pelvic bones are joined together at the acetabulum, a cup-shaped socket that forms the hip joint and articulates with the head of the femur (thigh bone). The pelvic bones also have several openings for the passage of blood vessels, nerves, and reproductive and excretory organs.

The shape and size of the pelvic bones differ between males and females due to their different roles in childbirth and locomotion. Females typically have a wider and shallower pelvis than males to accommodate childbirth, while males usually have a narrower and deeper pelvis that is better suited for weight-bearing and movement.

Pseudarthrosis is a medical term that refers to a false joint or a nonunion of bones, meaning that the broken bone ends do not heal properly and continue to move at the fracture site. This condition can cause pain, instability, and deformity in the affected limb. It may require additional treatment such as surgery to promote bone healing and stabilization.

Thoracotomy is a surgical procedure that involves making an incision on the chest wall to gain access to the thoracic cavity, which contains the lungs, heart, esophagus, trachea, and other vital organs. The incision can be made on the side (lateral thoracotomy), back (posterolateral thoracotomy), or front (median sternotomy) of the chest wall, depending on the specific surgical indication.

Thoracotomy is performed for various indications, including lung biopsy, lung resection, esophagectomy, heart surgery, and mediastinal mass removal. The procedure allows the surgeon to directly visualize and access the organs within the thoracic cavity, perform necessary procedures, and control bleeding if needed.

After the procedure, the incision is typically closed with sutures or staples, and a chest tube may be placed to drain any accumulated fluid or air from the pleural space around the lungs. The patient will require postoperative care and monitoring in a hospital setting until their condition stabilizes.

Duchenne Muscular Dystrophy (DMD) is a genetic disorder characterized by progressive muscle weakness and degeneration. It is caused by the absence of dystrophin, a protein that helps keep muscle cells intact. Without dystrophin, the muscle cells break down and are replaced with scar tissue, leading to loss of muscle function over time.

DMD primarily affects boys, as it is inherited in an X-linked recessive pattern, meaning that females who carry one affected X chromosome typically do not show symptoms but can pass the gene on to their offspring. Symptoms usually begin in early childhood and include difficulty with motor skills such as walking, running, and climbing stairs. Over time, the muscle weakness progresses and can lead to loss of ambulation, respiratory and cardiac complications, and ultimately, premature death.

Currently, there is no cure for DMD, but various treatments such as corticosteroids, physical therapy, and assisted ventilation can help manage symptoms and improve quality of life. Gene therapy approaches are also being investigated as potential treatments for this disorder.

Somatosensory evoked potentials (SEPs) are electrical signals generated in the brain and spinal cord in response to the stimulation of peripheral nerves. These responses are recorded and measured to assess the functioning of the somatosensory system, which is responsible for processing sensations such as touch, temperature, vibration, and proprioception (the sense of the position and movement of body parts).

SEPs are typically elicited by applying electrical stimuli to peripheral nerves in the arms or legs. The resulting neural responses are then recorded using electrodes placed on the scalp or other locations on the body. These recordings can provide valuable information about the integrity and function of the nervous system, and are often used in clinical settings to diagnose and monitor conditions such as nerve damage, spinal cord injury, multiple sclerosis, and other neurological disorders.

SEPs can be further categorized based on the specific type of stimulus used and the location of the recording electrodes. For example, short-latency SEPs (SLSEPs) are those that occur within the first 50 milliseconds after stimulation, and are typically recorded from the scalp over the primary sensory cortex. These responses reflect the earliest stages of sensory processing and can be used to assess the integrity of the peripheral nerves and the ascending sensory pathways in the spinal cord.

In contrast, long-latency SEPs (LLSEPs) occur after 50 milliseconds and are typically recorded from more posterior regions of the scalp over the parietal cortex. These responses reflect later stages of sensory processing and can be used to assess higher-level cognitive functions such as attention, memory, and perception.

Overall, SEPs provide a valuable tool for clinicians and researchers seeking to understand the functioning of the somatosensory system and diagnose or monitor neurological disorders.

Postoperative complications refer to any unfavorable condition or event that occurs during the recovery period after a surgical procedure. These complications can vary in severity and may include, but are not limited to:

1. Infection: This can occur at the site of the incision or inside the body, such as pneumonia or urinary tract infection.
2. Bleeding: Excessive bleeding (hemorrhage) can lead to a drop in blood pressure and may require further surgical intervention.
3. Blood clots: These can form in the deep veins of the legs (deep vein thrombosis) and can potentially travel to the lungs (pulmonary embolism).
4. Wound dehiscence: This is when the surgical wound opens up, which can lead to infection and further complications.
5. Pulmonary issues: These include atelectasis (collapsed lung), pneumonia, or respiratory failure.
6. Cardiovascular problems: These include abnormal heart rhythms (arrhythmias), heart attack, or stroke.
7. Renal failure: This can occur due to various reasons such as dehydration, blood loss, or the use of certain medications.
8. Pain management issues: Inadequate pain control can lead to increased stress, anxiety, and decreased mobility.
9. Nausea and vomiting: These can be caused by anesthesia, opioid pain medication, or other factors.
10. Delirium: This is a state of confusion and disorientation that can occur in the elderly or those with certain medical conditions.

Prompt identification and management of these complications are crucial to ensure the best possible outcome for the patient.

Biomechanics is the application of mechanical laws to living structures and systems, particularly in the field of medicine and healthcare. A biomechanical phenomenon refers to a observable event or occurrence that involves the interaction of biological tissues or systems with mechanical forces. These phenomena can be studied at various levels, from the molecular and cellular level to the tissue, organ, and whole-body level.

Examples of biomechanical phenomena include:

1. The way that bones and muscles work together to produce movement (known as joint kinematics).
2. The mechanical behavior of biological tissues such as bone, cartilage, tendons, and ligaments under various loads and stresses.
3. The response of cells and tissues to mechanical stimuli, such as the way that bone tissue adapts to changes in loading conditions (known as Wolff's law).
4. The biomechanics of injury and disease processes, such as the mechanisms of joint injury or the development of osteoarthritis.
5. The use of mechanical devices and interventions to treat medical conditions, such as orthopedic implants or assistive devices for mobility impairments.

Understanding biomechanical phenomena is essential for developing effective treatments and prevention strategies for a wide range of medical conditions, from musculoskeletal injuries to neurological disorders.

Myelography is a medical imaging technique used to examine the spinal cord and surrounding structures, such as the spinal nerves, intervertebral discs, and the spinal column. This procedure involves the injection of a contrast dye into the subarachnoid space, which is the area surrounding the spinal cord filled with cerebrospinal fluid (CSF). The dye outlines the spinal structures, making them visible on X-ray or CT scan images.

The primary purpose of myelography is to diagnose various spinal conditions, including herniated discs, spinal stenosis, tumors, infection, and traumatic injuries. It can help identify any compression or irritation of the spinal cord or nerves that may be causing pain, numbness, weakness, or other neurological symptoms.

The procedure typically requires the patient to lie flat on their stomach or side while the radiologist inserts a thin needle into the subarachnoid space, usually at the lower lumbar level. Once the contrast dye is injected, the patient will be repositioned for various X-ray views or undergo a CT scan to capture detailed images of the spine. After the procedure, patients may experience headaches, nausea, or discomfort at the injection site, but these symptoms usually resolve within a few days.

Ocular motility disorders refer to a group of conditions that affect the movement of the eyes. These disorders can result from nerve damage, muscle dysfunction, or brain injuries. They can cause abnormal eye alignment, limited range of motion, and difficulty coordinating eye movements. Common symptoms include double vision, blurry vision, strabismus (crossed eyes), nystagmus (involuntary eye movement), and difficulty tracking moving objects. Ocular motility disorders can be congenital or acquired and may require medical intervention to correct or manage the condition.

The thorax is the central part of the human body, located between the neck and the abdomen. In medical terms, it refers to the portion of the body that contains the heart, lungs, and associated structures within a protective cage made up of the sternum (breastbone), ribs, and thoracic vertebrae. The thorax is enclosed by muscles and protected by the ribcage, which helps to maintain its structural integrity and protect the vital organs contained within it.

The thorax plays a crucial role in respiration, as it allows for the expansion and contraction of the lungs during breathing. This movement is facilitated by the flexible nature of the ribcage, which expands and contracts with each breath, allowing air to enter and exit the lungs. Additionally, the thorax serves as a conduit for major blood vessels, such as the aorta and vena cava, which carry blood to and from the heart and the rest of the body.

Understanding the anatomy and function of the thorax is essential for medical professionals, as many conditions and diseases can affect this region of the body. These may include respiratory disorders such as pneumonia or chronic obstructive pulmonary disease (COPD), cardiovascular conditions like heart attacks or aortic aneurysms, and musculoskeletal issues involving the ribs, spine, or surrounding muscles.

Meningomyelocele is a type of neural tube defect that affects the development of the spinal cord and the surrounding membranes known as meninges. In this condition, a portion of the spinal cord and meninges protrude through an opening in the spine, creating a sac-like structure on the back. This sac is usually covered by skin, but it may be open in some cases.

Meningomyelocele can result in various neurological deficits, including muscle weakness, paralysis, and loss of sensation below the level of the lesion. It can also cause bladder and bowel dysfunction, as well as problems with sexual function. The severity of these symptoms depends on the location and extent of the spinal cord defect.

Early diagnosis and treatment are crucial for managing meningomyelocele and preventing further complications. Treatment typically involves surgical closure of the opening in the spine to protect the spinal cord and prevent infection. Physical therapy, occupational therapy, and other supportive care measures may also be necessary to help individuals with meningomyelocele achieve their full potential for mobility and independence.

Follow-up studies are a type of longitudinal research that involve repeated observations or measurements of the same variables over a period of time, in order to understand their long-term effects or outcomes. In medical context, follow-up studies are often used to evaluate the safety and efficacy of medical treatments, interventions, or procedures.

In a typical follow-up study, a group of individuals (called a cohort) who have received a particular treatment or intervention are identified and then followed over time through periodic assessments or data collection. The data collected may include information on clinical outcomes, adverse events, changes in symptoms or functional status, and other relevant measures.

The results of follow-up studies can provide important insights into the long-term benefits and risks of medical interventions, as well as help to identify factors that may influence treatment effectiveness or patient outcomes. However, it is important to note that follow-up studies can be subject to various biases and limitations, such as loss to follow-up, recall bias, and changes in clinical practice over time, which must be carefully considered when interpreting the results.

The sacrum is a triangular-shaped bone in the lower portion of the human vertebral column, located between the lumbar spine and the coccyx (tailbone). It forms through the fusion of several vertebrae during fetal development. The sacrum's base articulates with the fifth lumbar vertebra, while its apex connects with the coccyx.

The sacrum plays an essential role in supporting the spine and transmitting weight from the upper body to the pelvis and lower limbs. It also serves as an attachment site for various muscles and ligaments. The sacral region is often a focus in medical and chiropractic treatments due to its importance in spinal stability, posture, and overall health.

Spinal diseases refer to a range of medical conditions that affect the spinal column, which is made up of vertebrae (bones), intervertebral discs, facet joints, nerves, ligaments, and muscles. These diseases can cause pain, discomfort, stiffness, numbness, weakness, or even paralysis, depending on the severity and location of the condition. Here are some examples of spinal diseases:

1. Degenerative disc disease: This is a condition where the intervertebral discs lose their elasticity and height, leading to stiffness, pain, and decreased mobility.
2. Herniated disc: This occurs when the inner material of the intervertebral disc bulges or herniates out through a tear in the outer layer, causing pressure on the spinal nerves and resulting in pain, numbness, tingling, or weakness in the affected area.
3. Spinal stenosis: This is a narrowing of the spinal canal or the neural foramen (the openings where the spinal nerves exit the spinal column), which can cause pressure on the spinal cord or nerves and result in pain, numbness, tingling, or weakness.
4. Scoliosis: This is a curvature of the spine that can occur in children or adults, leading to an abnormal posture, back pain, and decreased lung function.
5. Osteoarthritis: This is a degenerative joint disease that affects the facet joints in the spine, causing pain, stiffness, and decreased mobility.
6. Ankylosing spondylitis: This is a chronic inflammatory disease that affects the spine and sacroiliac joints, leading to pain, stiffness, and fusion of the vertebrae.
7. Spinal tumors: These are abnormal growths that can occur in the spinal column, which can be benign or malignant, causing pain, neurological symptoms, or even paralysis.
8. Infections: Bacterial or viral infections can affect the spine, leading to pain, fever, and other systemic symptoms.
9. Trauma: Fractures, dislocations, or sprains of the spine can occur due to accidents, falls, or sports injuries, causing pain, neurological deficits, or even paralysis.

Three-dimensional (3D) imaging in medicine refers to the use of technologies and techniques that generate a 3D representation of internal body structures, organs, or tissues. This is achieved by acquiring and processing data from various imaging modalities such as X-ray computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, or confocal microscopy. The resulting 3D images offer a more detailed visualization of the anatomy and pathology compared to traditional 2D imaging techniques, allowing for improved diagnostic accuracy, surgical planning, and minimally invasive interventions.

In 3D imaging, specialized software is used to reconstruct the acquired data into a volumetric model, which can be manipulated and viewed from different angles and perspectives. This enables healthcare professionals to better understand complex anatomical relationships, detect abnormalities, assess disease progression, and monitor treatment response. Common applications of 3D imaging include neuroimaging, orthopedic surgery planning, cancer staging, dental and maxillofacial reconstruction, and interventional radiology procedures.

The lumbosacral region is the lower part of the back where the lumbar spine (five vertebrae in the lower back) connects with the sacrum (a triangular bone at the base of the spine). This region is subject to various conditions such as sprains, strains, herniated discs, and degenerative disorders that can cause pain and discomfort. It's also a common site for surgical intervention when non-surgical treatments fail to provide relief.

Musculoskeletal abnormalities refer to structural and functional disorders that affect the musculoskeletal system, which includes the bones, muscles, cartilages, tendons, ligaments, joints, and other related tissues. These abnormalities can result from genetic factors, trauma, overuse, degenerative processes, infections, or tumors. They may cause pain, stiffness, limited mobility, deformity, weakness, and susceptibility to injuries. Examples of musculoskeletal abnormalities include osteoarthritis, rheumatoid arthritis, scoliosis, kyphosis, lordosis, fractures, dislocations, tendinitis, bursitis, myopathies, and various congenital conditions.

Thoracic diseases refer to a range of medical conditions that affect the thorax, which is the part of the body that includes the chest cage, lungs, pleura (lining of the lungs), mediastinum (the area between the lungs), and diaphragm. Examples of thoracic diseases include:

1. Chronic obstructive pulmonary disease (COPD): A progressive lung disease characterized by difficulty breathing, cough, and sputum production.
2. Asthma: A chronic inflammatory disorder of the airways that causes wheezing, shortness of breath, chest tightness, and coughing.
3. Lung cancer: A malignant tumor that forms in the tissues of the lungs, usually in the cells lining the air passages.
4. Pneumonia: An infection of the lung tissue that can be caused by bacteria, viruses, or fungi.
5. Tuberculosis (TB): A bacterial infection that mainly affects the lungs but can also affect other parts of the body.
6. Pleural effusion: An abnormal accumulation of fluid in the pleural space between the lungs and the chest wall.
7. Pneumothorax: A collection of air in the pleural space that causes the lung to collapse.
8. Lung fibrosis: A condition characterized by scarring and thickening of the lung tissue, leading to difficulty breathing.
9. Esophageal cancer: A malignant tumor that forms in the tissues of the esophagus, the tube that connects the throat to the stomach.
10. Thoracic aortic aneurysm: A bulging or weakened area in the wall of the thoracic aorta, the largest artery in the body.

These are just a few examples of thoracic diseases, and there are many others that can affect the chest and lungs.

A melatonin receptor is a type of G protein-coupled receptor (GPCR) that binds to the hormone melatonin, which is primarily involved in regulating sleep-wake cycles. There are two main subtypes of melatonin receptors, MT1 and MT2, which are encoded by the genes MTNR1A and MTNR1B, respectively.

MT2 receptor, also known as Mel1b or MTNR1B, is a subtype of melatonin receptor that is widely expressed in various tissues, including the retina, brain, heart, and gastrointestinal tract. MT2 receptors are involved in several physiological functions, such as circadian rhythm regulation, sleep onset and duration, and neuroprotection.

MT2 receptor activation has been shown to promote sleep onset and consolidation, reduce anxiety and depressive-like behaviors, and improve cognitive function. Additionally, MT2 receptors have been implicated in the regulation of glucose metabolism, insulin secretion, and energy homeostasis, suggesting a potential role in the treatment of metabolic disorders such as diabetes.

Overall, melatonin receptors, particularly the MT2 subtype, are important targets for developing therapies for sleep disorders, neuropsychiatric conditions, and metabolic diseases.

I'm not aware of a medical term called "bone wires." The term "wiring" is used in orthopedic surgery to describe the use of metal wire to hold bones or fractures in place during healing. However, I couldn't find any specific medical definition or term related to "bone wires." It may be a colloquialism, a term used in a specific context, or a term from science fiction. If you could provide more context about where you encountered this term, I might be able to give a more accurate answer.

Spondylolisthesis is a medical condition that affects the spine, specifically the vertebrae in the lower back (lumbar region). It occurs when one vertebra slips forward and onto the vertebra below it. This slippage can lead to narrowing of the spinal canal and compression of the nerves exiting the spine, causing pain and discomfort. The condition can be congenital, degenerative, or result from trauma or injury. Symptoms may include lower back pain, stiffness, and radiating pain down the legs. Treatment options range from physical therapy and pain management to surgical intervention in severe cases.

Preoperative care refers to the series of procedures, interventions, and preparations that are conducted before a surgical operation. The primary goal of preoperative care is to ensure the patient's well-being, optimize their physical condition, reduce potential risks, and prepare them mentally and emotionally for the upcoming surgery.

Preoperative care typically includes:

1. Preoperative assessment: A thorough evaluation of the patient's overall health status, including medical history, physical examination, laboratory tests, and diagnostic imaging, to identify any potential risk factors or comorbidities that may impact the surgical procedure and postoperative recovery.
2. Informed consent: The process of ensuring the patient understands the nature of the surgery, its purpose, associated risks, benefits, and alternative treatment options. The patient signs a consent form indicating they have been informed and voluntarily agree to undergo the surgery.
3. Preoperative instructions: Guidelines provided to the patient regarding their diet, medication use, and other activities in the days leading up to the surgery. These instructions may include fasting guidelines, discontinuing certain medications, or arranging for transportation after the procedure.
4. Anesthesia consultation: A meeting with the anesthesiologist to discuss the type of anesthesia that will be used during the surgery and address any concerns related to anesthesia risks, side effects, or postoperative pain management.
5. Preparation of the surgical site: Cleaning and shaving the area where the incision will be made, as well as administering appropriate antimicrobial agents to minimize the risk of infection.
6. Medical optimization: Addressing any underlying medical conditions or correcting abnormalities that may negatively impact the surgical outcome. This may involve adjusting medications, treating infections, or managing chronic diseases such as diabetes.
7. Emotional and psychological support: Providing counseling, reassurance, and education to help alleviate anxiety, fear, or emotional distress related to the surgery.
8. Preoperative holding area: The patient is transferred to a designated area near the operating room where they are prepared for surgery by changing into a gown, having intravenous (IV) lines inserted, and receiving monitoring equipment.

By following these preoperative care guidelines, healthcare professionals aim to ensure that patients undergo safe and successful surgical procedures with optimal outcomes.

Spinal dysraphism is a broad term used to describe a group of congenital malformations of the spine and spinal cord. These defects occur during embryonic development when the neural tube, which eventually forms the brain and spinal cord, fails to close properly. This results in an incomplete development or formation of the spinal cord and/or vertebral column.

There are two main categories of spinal dysraphism: open (also called exposed or overt) and closed (also called hidden or occult). Open spinal dysraphisms, such as myelomeningocele and myelocele, involve exposure of the spinal cord and/or its coverings through an opening in the back. Closed spinal dysraphisms, such as lipomyelomeningocele, tethered cord syndrome, and diastematomyelia, are more subtle and may not be visibly apparent at birth.

Symptoms of spinal dysraphism can vary widely depending on the type and severity of the defect. They may include motor and sensory impairments, bowel and bladder dysfunction, orthopedic deformities, and increased risk for neurological complications such as hydrocephalus (accumulation of fluid in the brain). Early diagnosis and intervention are crucial to optimize outcomes and minimize potential complications.

Surgical casts are medical devices used to immobilize and protect injured body parts, typically fractured or broken bones, during the healing process. They are usually made of plaster or fiberglass materials that harden when wet and conform to the shape of the affected area once applied. The purpose of a surgical cast is to restrict movement and provide stability to the injured site, allowing for proper alignment and healing of the bones.

The casting process involves first aligning the broken bone fragments into their correct positions, often through manual manipulation or surgical intervention. Once aligned, the cast material is applied in layers, with each layer being allowed to dry before adding the next. This creates a rigid structure that encases and supports the injured area. The cast must be kept dry during the healing process to prevent it from becoming weakened or damaged.

Surgical casts come in various shapes and sizes depending on the location and severity of the injury. They may also include additional components such as padding, Velcro straps, or window openings to allow for regular monitoring of the skin and underlying tissue. In some cases, removable splints or functional braces may be used instead of traditional casts, providing similar support while allowing for limited movement and easier adjustments.

It is essential to follow proper care instructions when wearing a surgical cast, including elevating the injured limb, avoiding excessive weight-bearing, and monitoring for signs of complications such as swelling, numbness, or infection. Regular check-ups with a healthcare provider are necessary to ensure proper healing and adjust the cast if needed.

Intraoperative monitoring (IOM) is the practice of using specialized techniques to monitor physiological functions or neural structures in real-time during surgical procedures. The primary goal of IOM is to provide continuous information about the patient's status and the effects of surgery on neurological function, allowing surgeons to make informed decisions and minimize potential risks.

IOM can involve various methods such as:

1. Electrophysiological monitoring: This includes techniques like somatosensory evoked potentials (SSEP), motor evoked potentials (MEP), and electroencephalography (EEG) to assess the integrity of neural pathways and brain function during surgery.
2. Neuromonitoring: Direct electrical stimulation of nerves or spinal cord structures can help identify critical neuroanatomical structures, evaluate their functional status, and guide surgical interventions.
3. Hemodynamic monitoring: Measuring blood pressure, heart rate, cardiac output, and oxygen saturation helps assess the patient's overall physiological status during surgery.
4. Imaging modalities: Intraoperative imaging techniques like ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) can provide real-time visualization of anatomical structures and surgical progress.

The specific IOM methods employed depend on the type of surgery, patient characteristics, and potential risks involved. Intraoperative monitoring is particularly crucial in procedures where there is a risk of neurological injury, such as spinal cord or brain surgeries, vascular interventions, or tumor resections near critical neural structures.

Cerebral palsy (CP) is a group of disorders that affect a person's ability to move and maintain balance and posture. According to the Mayo Clinic, CP is caused by abnormal brain development or damage to the developing brain that affects a child's ability to control movement.

The symptoms of cerebral palsy can vary in severity and may include:

* Spasticity (stiff or tight muscles)
* Rigidity (resistance to passive movement)
* Poor coordination and balance
* Weakness or paralysis
* Tremors or involuntary movements
* Abnormal gait or difficulty walking
* Difficulty with fine motor skills, such as writing or using utensils
* Speech and language difficulties
* Vision, hearing, or swallowing problems

It's important to note that cerebral palsy is not a progressive condition, meaning that it does not worsen over time. However, the symptoms may change over time, and some individuals with CP may experience additional medical conditions as they age.

Cerebral palsy is usually caused by brain damage that occurs before or during birth, but it can also be caused by brain injuries that occur in the first few years of life. Some possible causes of cerebral palsy include:

* Infections during pregnancy
* Lack of oxygen to the brain during delivery
* Traumatic head injury during birth
* Brain bleeding or stroke in the newborn period
* Genetic disorders
* Maternal illness or infection during pregnancy

There is no cure for cerebral palsy, but early intervention and treatment can help improve outcomes and quality of life. Treatment may include physical therapy, occupational therapy, speech therapy, medications to manage symptoms, surgery, and assistive devices such as braces or wheelchairs.

Back pain is a common symptom characterized by discomfort or soreness in the back, often occurring in the lower region of the back (lumbago). It can range from a mild ache to a sharp stabbing or shooting pain, and it may be accompanied by stiffness, restricted mobility, and difficulty performing daily activities. Back pain is typically caused by strain or sprain to the muscles, ligaments, or spinal joints, but it can also result from degenerative conditions, disc herniation, spinal stenosis, osteoarthritis, or other medical issues affecting the spine. The severity and duration of back pain can vary widely, with some cases resolving on their own within a few days or weeks, while others may require medical treatment and rehabilitation.

Thoracic radiography is a type of diagnostic imaging that involves using X-rays to produce images of the chest, including the lungs, heart, bronchi, great vessels, and the bones of the spine and chest wall. It is a commonly used tool in the diagnosis and management of various respiratory, cardiovascular, and thoracic disorders such as pneumonia, lung cancer, heart failure, and rib fractures.

During the procedure, the patient is positioned between an X-ray machine and a cassette containing a film or digital detector. The X-ray beam is directed at the chest, and the resulting image is captured on the film or detector. The images produced can help identify any abnormalities in the structure or function of the organs within the chest.

Thoracic radiography may be performed as a routine screening test for certain conditions, such as lung cancer, or it may be ordered when a patient presents with symptoms suggestive of a respiratory or cardiovascular disorder. It is a safe and non-invasive procedure that can provide valuable information to help guide clinical decision making and improve patient outcomes.

'Abnormalities, Multiple' is a broad term that refers to the presence of two or more structural or functional anomalies in an individual. These abnormalities can be present at birth (congenital) or can develop later in life (acquired). They can affect various organs and systems of the body and can vary greatly in severity and impact on a person's health and well-being.

Multiple abnormalities can occur due to genetic factors, environmental influences, or a combination of both. Chromosomal abnormalities, gene mutations, exposure to teratogens (substances that cause birth defects), and maternal infections during pregnancy are some of the common causes of multiple congenital abnormalities.

Examples of multiple congenital abnormalities include Down syndrome, Turner syndrome, and VATER/VACTERL association. Acquired multiple abnormalities can result from conditions such as trauma, infection, degenerative diseases, or cancer.

The medical evaluation and management of individuals with multiple abnormalities depend on the specific abnormalities present and their impact on the individual's health and functioning. A multidisciplinary team of healthcare professionals is often involved in the care of these individuals to address their complex needs.

Conjoined twins, also known as Siamese twins, are a rare type of monozygotic (identical) twins who are born physically connected to each other. They develop from a single fertilized egg that fails to fully separate, resulting in various degrees of fusion between their bodies. The point of connection and the extent of sharing body parts can vary greatly between sets of conjoined twins. Some may be connected at the chest, abdomen, or hips, while others may share vital organs such as the heart or brain. Treatment options depend on the type of conjunction and whether separation is possible without causing harm to either twin. Conjoined twins occur in about 1 in every 200,000 live births.

Fibrous Dysplasia of Bone is a rare, benign bone disorder that is characterized by the replacement of normal bone tissue with fibrous (scar-like) and immature bone tissue. This results in weakened bones that are prone to fractures, deformities, and pain. The condition can affect any bone in the body but most commonly involves the long bones of the legs, arms, and skull. It can occur as an isolated finding or as part of a genetic disorder called McCune-Albright syndrome. The exact cause of fibrous dysplasia is not fully understood, but it is believed to result from a genetic mutation that occurs during early bone development. There is no cure for fibrous dysplasia, and treatment typically focuses on managing symptoms and preventing complications.

Disease progression is the worsening or advancement of a medical condition over time. It refers to the natural course of a disease, including its development, the severity of symptoms and complications, and the impact on the patient's overall health and quality of life. Understanding disease progression is important for developing appropriate treatment plans, monitoring response to therapy, and predicting outcomes.

The rate of disease progression can vary widely depending on the type of medical condition, individual patient factors, and the effectiveness of treatment. Some diseases may progress rapidly over a short period of time, while others may progress more slowly over many years. In some cases, disease progression may be slowed or even halted with appropriate medical interventions, while in other cases, the progression may be inevitable and irreversible.

In clinical practice, healthcare providers closely monitor disease progression through regular assessments, imaging studies, and laboratory tests. This information is used to guide treatment decisions and adjust care plans as needed to optimize patient outcomes and improve quality of life.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

A "torsion abnormality" is not a standard medical term, but I believe you are asking about torsional deformities or abnormalities related to torsion. Torsion refers to a twisting force or movement that can cause structures to rotate around their long axis. In the context of medical definitions:

Torsional abnormality could refer to a congenital or acquired condition where anatomical structures, such as blood vessels, muscles, tendons, or bones, are twisted or rotated in an abnormal way. This can lead to various complications depending on the structure involved and the degree of torsion.

For instance, in congenital torsional deformities of long bones (like tibia or femur), the rotation of the bone axis can cause issues with gait, posture, and joint function. In some cases, this may require surgical intervention to correct the abnormality.

In the context of vascular torsion abnormalities, such as mesenteric torsion, it could lead to bowel ischemia due to the twisting of blood vessels that supply the intestines. This can be a surgical emergency and requires immediate intervention to restore blood flow and prevent further damage.

It's essential to consult with a medical professional for a precise diagnosis and treatment options if you or someone else experiences symptoms related to torsional abnormalities.

A contracture, in a medical context, refers to the abnormal shortening and hardening of muscles, tendons, or other tissue, which can result in limited mobility and deformity of joints. This condition can occur due to various reasons such as injury, prolonged immobilization, scarring, neurological disorders, or genetic conditions.

Contractures can cause significant impairment in daily activities and quality of life, making it difficult for individuals to perform routine tasks like dressing, bathing, or walking. Treatment options may include physical therapy, splinting, casting, medications, surgery, or a combination of these approaches, depending on the severity and underlying cause of the contracture.

A Severity of Illness Index is a measurement tool used in healthcare to assess the severity of a patient's condition and the risk of mortality or other adverse outcomes. These indices typically take into account various physiological and clinical variables, such as vital signs, laboratory values, and co-morbidities, to generate a score that reflects the patient's overall illness severity.

Examples of Severity of Illness Indices include the Acute Physiology and Chronic Health Evaluation (APACHE) system, the Simplified Acute Physiology Score (SAPS), and the Mortality Probability Model (MPM). These indices are often used in critical care settings to guide clinical decision-making, inform prognosis, and compare outcomes across different patient populations.

It is important to note that while these indices can provide valuable information about a patient's condition, they should not be used as the sole basis for clinical decision-making. Rather, they should be considered in conjunction with other factors, such as the patient's overall clinical presentation, treatment preferences, and goals of care.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

Rett Syndrome is a rare, progressive neurodevelopmental disorder that almost exclusively affects females. It is caused by mutations in the MECP2 gene, which provides instructions for making a protein essential for normal brain function. The symptoms of Rett Syndrome typically appear after a period of apparently normal development and can include:

1. Loss of purposeful hand skills, replaced with repetitive, stereotyped movements such as hand wringing or washing
2. Slowed growth and reduced body weight
3. Impaired speech and language skills, although many individuals can understand complex commands
4. Breathing difficulties, including hyperventilation, apnea (breath holding), and air swallowing
5. Impaired muscle tone, which can range from too loose to too rigid
6. Scoliosis or other spinal deformities
7. Seizures
8. Sleep disturbances
9. Anxiety and gastrointestinal issues

The progression of Rett Syndrome varies among individuals, but most require assistance with daily living activities. Despite the challenges associated with this disorder, many individuals with Rett Syndrome live into middle age or beyond.

The pineal gland, also known as the epiphysis cerebri, is a small endocrine gland located in the brain. It is shaped like a pinecone, hence its name, and is situated near the center of the brain, between the two hemispheres, attached to the third ventricle. The primary function of the pineal gland is to produce melatonin, a hormone that helps regulate sleep-wake cycles and circadian rhythms in response to light and darkness. Additionally, it plays a role in the onset of puberty and has been suggested to have other functions related to cognition, mood, and reproduction, although these are not as well understood.

Aicardi syndrome is a rare genetic disorder that primarily affects girls and women. It is characterized by the absence or underdevelopment of a part of the brain called the corpus callosum, which connects the two hemispheres of the brain. This results in various neurological symptoms such as seizures, developmental delays, and intellectual disabilities.

Individuals with Aicardi syndrome may also have other distinctive features, including abnormalities of the eyes (such as retinal lacunae or colobomas), agenesis of the corpus callosum, and characteristic skin abnormalities called chorioretinal lacunae. The disorder is usually sporadic, meaning that it occurs randomly and is not inherited from parents.

The exact cause of Aicardi syndrome is unknown, but it is believed to be related to genetic mutations or deletions on the X chromosome. Because the disorder primarily affects girls and women, it is thought that the absence of a second X chromosome in males may lead to more severe symptoms or early lethality.

There is no cure for Aicardi syndrome, and treatment is focused on managing the symptoms and improving quality of life. This may include anti-seizure medications, physical therapy, occupational therapy, and special education services. The prognosis for individuals with Aicardi syndrome varies widely depending on the severity of their symptoms and the effectiveness of treatment.

Vital capacity (VC) is a term used in pulmonary function tests to describe the maximum volume of air that can be exhaled after taking a deep breath. It is the sum of inspiratory reserve volume, tidal volume, and expiratory reserve volume. In other words, it's the total amount of air you can forcibly exhale after inhaling as deeply as possible. Vital capacity is an important measurement in assessing lung function and can be reduced in conditions such as chronic obstructive pulmonary disease (COPD), asthma, and other respiratory disorders.

The thoracic wall refers to the anatomical structure that surrounds and protects the chest cavity or thorax, which contains the lungs, heart, and other vital organs. It is composed of several components:

1. Skeletal framework: This includes the 12 pairs of ribs, the sternum (breastbone) in the front, and the thoracic vertebrae in the back. The upper seven pairs of ribs are directly attached to the sternum in the front through costal cartilages. The lower five pairs of ribs are not directly connected to the sternum but are joined to the ribs above them.
2. Muscles: The thoracic wall contains several muscles, including the intercostal muscles (located between the ribs), the scalene muscles (at the side and back of the neck), and the serratus anterior muscle (on the sides of the chest). These muscles help in breathing by expanding and contracting the ribcage.
3. Soft tissues: The thoracic wall also contains various soft tissues, such as fascia, nerves, blood vessels, and fat. These structures support the functioning of the thoracic organs and contribute to the overall stability and protection of the chest cavity.

The primary function of the thoracic wall is to protect the vital organs within the chest cavity while allowing for adequate movement during respiration. Additionally, it provides a stable base for the attachment of various muscles involved in upper limb movement and posture.

Postural balance is the ability to maintain, achieve, or restore a state of equilibrium during any posture or activity. It involves the integration of sensory information (visual, vestibular, and proprioceptive) to control and adjust body position in space, thereby maintaining the center of gravity within the base of support. This is crucial for performing daily activities and preventing falls, especially in older adults and individuals with neurological or orthopedic conditions.

Orthopedics is a branch of medicine that deals with the prevention, diagnosis, and treatment of disorders of the musculoskeletal system, which includes the bones, joints, muscles, ligaments, tendons, and nerves. The goal of orthopedic care is to help patients maintain or restore their mobility, function, and quality of life through a variety of treatments, including medication, physical therapy, bracing, and surgery. Orthopedic surgeons are medical doctors who have completed additional training in the diagnosis and treatment of musculoskeletal conditions, and they may specialize in specific areas such as sports medicine, spine care, joint replacement, or pediatric orthopedics.

Postoperative care refers to the comprehensive medical treatment and nursing attention provided to a patient following a surgical procedure. The goal of postoperative care is to facilitate the patient's recovery, prevent complications, manage pain, ensure proper healing of the incision site, and maintain overall health and well-being until the patient can resume their normal activities.

This type of care includes monitoring vital signs, managing pain through medication or other techniques, ensuring adequate hydration and nutrition, helping the patient with breathing exercises to prevent lung complications, encouraging mobility to prevent blood clots, monitoring for signs of infection or other complications, administering prescribed medications, providing wound care, and educating the patient about postoperative care instructions.

The duration of postoperative care can vary depending on the type and complexity of the surgical procedure, as well as the individual patient's needs and overall health status. It may be provided in a hospital setting, an outpatient surgery center, or in the patient's home, depending on the level of care required.

The spinal canal is the bony, protective channel within the vertebral column that contains and houses the spinal cord. It extends from the foramen magnum at the base of the skull to the sacrum, where the spinal cord ends and forms the cauda equina. The spinal canal is formed by a series of vertebral bodies stacked on top of each other, intervertebral discs in between them, and the laminae and spinous processes that form the posterior elements of the vertebrae. The spinal canal provides protection to the spinal cord from external trauma and contains cerebrospinal fluid (CSF) that circulates around the cord, providing nutrients and cushioning. Any narrowing or compression of the spinal canal, known as spinal stenosis, can cause various neurological symptoms due to pressure on the spinal cord or nerve roots.

Paraspinal muscles are a group of muscles that run along the vertebral column, primarily on either side of the spine. These muscles play an essential role in providing stability, support, and mobility to the spine. They assist in movements such as bending, rotating, and extending the trunk, and help maintain proper posture.

There are several layers of paraspinal muscles, including:

1. Erector spinae: A set of three columns of muscles (iliocostalis, longissimus, and spinalis) that extend from the sacrum to the skull, helping to straighten and rotate the spine.
2. Multifidus: Deep muscles that attach directly to individual vertebrae, providing stability and limiting excessive movement between them.
3. Semispinalis: A group of muscles located more superficially than the multifidus but deeper than the erector spinae, which help extend the spine.
4. Rotators: Smaller muscles that assist in rotating and stabilizing the vertebral column.

Paraspinal muscle dysfunction or injury can lead to back pain, stiffness, and decreased mobility. Proper care and conditioning of these muscles are crucial for maintaining a healthy spine and overall spinal function.

"Genu Varum" is a term used in orthopedics to describe a condition where the legs bow out at the knees, causing them to touch each other only at the ankles when standing with the feet and knees together. This is also commonly referred to as "bow-legged." It's important to note that this condition can be present from birth (congenital) or can develop later in life due to various reasons such as rickets, Blount's disease, or injuries. In some cases, it may require medical treatment to correct the alignment of the legs and prevent future complications.

Thoracic surgery, video-assisted (VATS) is a minimally invasive surgical technique used to diagnose and treat various conditions related to the chest cavity, including the lungs, pleura, mediastinum, esophagus, and diaphragm. In VATS, a thoracoscope, a type of endoscope with a camera and light source, is inserted through small incisions in the chest wall to provide visualization of the internal structures. The surgeon then uses specialized instruments to perform the necessary surgical procedures, such as biopsies, lung resections, or esophageal repairs. Compared to traditional open thoracic surgery, VATS typically results in less postoperative pain, shorter hospital stays, and quicker recoveries for patients.

Diskectomy is a surgical procedure in which all or part of an intervertebral disc (the cushion between two vertebrae) is removed. This procedure is typically performed to alleviate pressure on nerve roots or the spinal cord caused by a herniated or degenerative disc. In a diskectomy, the surgeon accesses the damaged disc through an incision in the back or neck and removes the portion of the disc that is causing the compression. This can help to relieve pain, numbness, tingling, or weakness in the affected limb. Diskectomy may be performed as an open surgery or using minimally invasive techniques, depending on the individual case.

Neuronavigation is a surgical technique that uses imaging technology, such as MRI or CT scans, to create a 3D map of the patient's brain in real-time during surgery. This allows surgeons to accurately locate and navigate to specific areas of the brain with greater precision and less invasiveness, improving surgical outcomes and reducing the risk of complications.

The neuronavigation system typically consists of a computer workstation, tracking systems, and instruments that are equipped with sensors. The system is able to track the position and orientation of these instruments relative to the patient's brain, allowing the surgeon to visualize the location of the instruments on the 3D map in real-time.

Neuronavigation has become an essential tool in many neurosurgical procedures, including tumor resection, functional neurosurgery, and deep brain stimulation. It enables surgeons to perform more complex surgeries with increased safety and efficacy, ultimately improving the quality of care for patients undergoing these procedures.

Intervertebral disc degeneration is a physiological and biochemical process that occurs in the spinal discs, which are located between each vertebra in the spine. These discs act as shock absorbers and allow for movement and flexibility of the spine.

The degenerative process involves changes in the structure and composition of the disc, including loss of water content, decreased production of proteoglycans (which help to maintain the disc's elasticity), and disorganization of the collagen fibers that make up the disc's outer layer (annulus fibrosus). These changes can lead to a decrease in the disc's height and mobility, as well as the development of tears or cracks in the annulus fibrosus.

In advanced stages of degeneration, the disc may herniate or bulge outward, causing pressure on nearby nerves and potentially leading to pain, numbness, tingling, or weakness in the affected area. It's worth noting that while intervertebral disc degeneration is a normal part of aging, certain factors such as injury, smoking, obesity, and repetitive stress can accelerate the process.

Anatomic landmarks are specific, identifiable structures or features on the body that are used as references in medicine and surgery. These landmarks can include bones, muscles, joints, or other visible or palpable features that help healthcare professionals identify specific locations, orient themselves during procedures, or measure changes in the body.

Examples of anatomic landmarks include:

* The anterior iliac spine, a bony prominence on the front of the pelvis that can be used to locate the hip joint.
* The cubital fossa, a depression at the elbow where the median nerve and brachial artery can be palpated.
* The navel (umbilicus), which serves as a reference point for measuring distances in the abdomen.
* The xiphoid process, a small piece of cartilage at the bottom of the breastbone that can be used to locate the heart and other structures in the chest.

Anatomic landmarks are important for accurate diagnosis, treatment planning, and surgical procedures, as they provide reliable and consistent reference points that can help ensure safe and effective care.

"Body weights and measures" is a general term that refers to the various methods used to quantify an individual's physical characteristics, particularly those related to health and fitness. This can include:

1. Body weight: The total amount of weight that a person's body possesses, typically measured in pounds or kilograms.
2. Height: The vertical distance from the bottom of the feet to the top of the head, usually measured in inches or centimeters.
3. Blood pressure: The force exerted by the blood on the walls of the arteries as it circulates through the body, typically measured in millimeters of mercury (mmHg).
4. Body mass index (BMI): A measure of body fat based on an individual's weight and height, calculated by dividing a person's weight in kilograms by their height in meters squared.
5. Waist circumference: The distance around the narrowest part of the waist, typically measured at the level of the belly button.
6. Hip circumference: The distance around the widest part of the hips, usually measured at the level of the greatest protrusion of the buttocks.
7. Blood glucose levels: The concentration of glucose in the blood, typically measured in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L).
8. Cholesterol levels: The amount of cholesterol present in the blood, usually measured in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L).

These and other body weights and measures are commonly used by healthcare professionals to assess an individual's health status, identify potential health risks, and guide treatment decisions.

Gait is a medical term used to describe the pattern of movement of the limbs during walking or running. It includes the manner or style of walking, including factors such as rhythm, speed, and step length. A person's gait can provide important clues about their physical health and neurological function, and abnormalities in gait may indicate the presence of underlying medical conditions, such as neuromuscular disorders, orthopedic problems, or injuries.

A typical human gait cycle involves two main phases: the stance phase, during which the foot is in contact with the ground, and the swing phase, during which the foot is lifted and moved forward in preparation for the next step. The gait cycle can be further broken down into several sub-phases, including heel strike, foot flat, midstance, heel off, and toe off.

Gait analysis is a specialized field of study that involves observing and measuring a person's gait pattern using various techniques, such as video recordings, force plates, and motion capture systems. This information can be used to diagnose and treat gait abnormalities, improve mobility and function, and prevent injuries.

The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.

The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.

The spinal cord is responsible for several vital functions, including:

1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.

Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.

Articular Range of Motion (AROM) is a term used in physiotherapy and orthopedics to describe the amount of movement available in a joint, measured in degrees of a circle. It refers to the range through which synovial joints can actively move without causing pain or injury. AROM is assessed by measuring the degree of motion achieved by active muscle contraction, as opposed to passive range of motion (PROM), where the movement is generated by an external force.

Assessment of AROM is important in evaluating a patient's functional ability and progress, planning treatment interventions, and determining return to normal activities or sports participation. It is also used to identify any restrictions in joint mobility that may be due to injury, disease, or surgery, and to monitor the effectiveness of rehabilitation programs.

The Tibial nerve is a major branch of the sciatic nerve that originates in the lower back and runs through the buttock and leg. It provides motor (nerve impulses that control muscle movement) and sensory (nerve impulses that convey information about touch, temperature, and pain) innervation to several muscles and skin regions in the lower limb.

More specifically, the Tibial nerve supplies the following structures:

1. Motor Innervation: The Tibial nerve provides motor innervation to the muscles in the back of the leg (posterior compartment), including the calf muscles (gastrocnemius and soleus) and the small muscles in the foot (intrinsic muscles). These muscles are responsible for plantarflexion (pointing the foot downward) and inversion (turning the foot inward) of the foot.
2. Sensory Innervation: The Tibial nerve provides sensory innervation to the skin on the sole of the foot, as well as the heel and some parts of the lower leg.

The Tibial nerve travels down the leg, passing behind the knee and through the calf, where it eventually joins with the common fibular (peroneal) nerve to form the tibial-fibular trunk. This trunk then divides into several smaller nerves that innervate the foot's intrinsic muscles and skin.

Damage or injury to the Tibial nerve can result in various symptoms, such as weakness or paralysis of the calf and foot muscles, numbness or tingling sensations in the sole of the foot, and difficulty walking or standing on tiptoes.

A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.

For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.

It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.

Surgical decompression is a medical procedure that involves relieving pressure on a nerve or tissue by creating additional space. This is typically accomplished through the removal of a portion of bone or other tissue that is causing the compression. The goal of surgical decompression is to alleviate symptoms such as pain, numbness, tingling, or weakness caused by the compression.

In the context of spinal disorders, surgical decompression is often used to treat conditions such as herniated discs, spinal stenosis, or bone spurs that are compressing nerves in the spine. The specific procedure used may vary depending on the location and severity of the compression, but common techniques include laminectomy, discectomy, and foraminotomy.

It's important to note that surgical decompression is a significant medical intervention that carries risks such as infection, bleeding, and injury to surrounding tissues. As with any surgery, it should be considered as a last resort after other conservative treatments have been tried and found to be ineffective. A thorough evaluation by a qualified medical professional is necessary to determine whether surgical decompression is appropriate in a given case.

Respiratory Function Tests (RFTs) are a group of medical tests that measure how well your lungs take in and exhale air, and how well they transfer oxygen and carbon dioxide into and out of your blood. They can help diagnose certain lung disorders, measure the severity of lung disease, and monitor response to treatment.

RFTs include several types of tests, such as:

1. Spirometry: This test measures how much air you can exhale and how quickly you can do it. It's often used to diagnose and monitor conditions like asthma, chronic obstructive pulmonary disease (COPD), and other lung diseases.
2. Lung volume testing: This test measures the total amount of air in your lungs. It can help diagnose restrictive lung diseases, such as pulmonary fibrosis or sarcoidosis.
3. Diffusion capacity testing: This test measures how well oxygen moves from your lungs into your bloodstream. It's often used to diagnose and monitor conditions like pulmonary fibrosis, interstitial lung disease, and other lung diseases that affect the ability of the lungs to transfer oxygen to the blood.
4. Bronchoprovocation testing: This test involves inhaling a substance that can cause your airways to narrow, such as methacholine or histamine. It's often used to diagnose and monitor asthma.
5. Exercise stress testing: This test measures how well your lungs and heart work together during exercise. It's often used to diagnose lung or heart disease.

Overall, Respiratory Function Tests are an important tool for diagnosing and managing a wide range of lung conditions.

Pectus Excavatum, commonly referred to as "Funnel Chest," is a congenital deformity of the chest wall where the sternum (breastbone) and rib cartilages grow inward, creating a sunken or caved-in appearance of the chest. This condition can vary in severity, from mild to severe, and may affect one's appearance, breathing, and overall health. In some cases, surgical intervention might be required to correct the deformity and improve related symptoms.

Electrodiagnosis, also known as electromyography (EMG), is a medical diagnostic procedure that evaluates the health and function of muscles and nerves. It measures the electrical activity of skeletal muscles at rest and during contraction, as well as the conduction of electrical signals along nerves.

The test involves inserting a thin needle electrode into the muscle to record its electrical activity. The physician will ask the patient to contract and relax the muscle while the electrical activity is recorded. The resulting data can help diagnose various neuromuscular disorders, such as nerve damage or muscle diseases, by identifying abnormalities in the electrical signals.

Electrodiagnosis can be used to diagnose conditions such as carpal tunnel syndrome, peripheral neuropathy, muscular dystrophy, and amyotrophic lateral sclerosis (ALS), among others. It is a valuable tool in the diagnosis and management of neuromuscular disorders, helping physicians to develop appropriate treatment plans for their patients.

"Weight-bearing" is a term used in the medical field to describe the ability of a body part or limb to support the weight or pressure exerted upon it, typically while standing, walking, or performing other physical activities. In a clinical setting, healthcare professionals often use the term "weight-bearing exercise" to refer to physical activities that involve supporting one's own body weight, such as walking, jogging, or climbing stairs. These exercises can help improve bone density, muscle strength, and overall physical function, particularly in individuals with conditions affecting the bones, joints, or muscles.

In addition, "weight-bearing" is also used to describe the positioning of a body part during medical imaging studies, such as X-rays or MRIs. For example, a weight-bearing X-ray of the foot or ankle involves taking an image while the patient stands on the affected limb, allowing healthcare providers to assess any alignment or stability issues that may not be apparent in a non-weight-bearing position.

Adolescent development is a phase of growth and development that occurs after childhood and before adulthood, typically between the ages of 10-24 years old. This stage is characterized by significant physical, cognitive, emotional, and social changes as an individual transitions from dependence to independence.

Physical development during adolescence includes significant growth spurts, hormonal changes, and sexual maturation, leading to puberty. Cognitive development involves the acquisition of abstract thinking, problem-solving, and decision-making skills. Emotional development is marked by increased self-awareness, self-esteem, and the ability to regulate emotions. Social development includes the formation of peer relationships, romantic relationships, and the development of a sense of identity and independence from family.

It's important to note that adolescent development can vary widely among individuals, and cultural, social, and environmental factors can significantly influence the course and outcome of this stage.

Thoracic surgical procedures refer to the operations that are performed on the thorax, which is the part of the body that lies between the neck and the abdomen and includes the chest cage, lungs, heart, great blood vessels, esophagus, diaphragm, and other organs in the chest cavity. These surgical procedures can be either open or minimally invasive (using small incisions and specialized instruments) and are performed to diagnose, treat, or manage various medical conditions affecting the thoracic organs, such as:

1. Lung cancer: Thoracic surgeons perform lung resections (lobectomy, segmentectomy, wedge resection) to remove cancerous lung tissue. They may also perform mediastinal lymph node dissection to assess the spread of the disease.
2. Esophageal surgery: Surgeries like esophagectomy are performed to treat esophageal cancer or other conditions affecting the esophagus, such as severe GERD (gastroesophageal reflux disease).
3. Chest wall surgery: This includes procedures to repair or replace damaged ribs, sternum, or chest wall muscles and treat conditions like pectus excavatum or tumors in the chest wall.
4. Heart surgery: Thoracic surgeons collaborate with cardiac surgeons to perform surgeries on the heart, such as coronary artery bypass grafting (CABG), valve repair/replacement, and procedures for treating aneurysms or dissections of the aorta.
5. Diaphragm surgery: Procedures like diaphragm plication are performed to treat paralysis or weakness of the diaphragm that can lead to respiratory insufficiency.
6. Mediastinal surgery: This involves operating on the mediastinum, the area between the lungs, to remove tumors, cysts, or other abnormal growths.
7. Pleural surgery: Procedures like pleurodesis or decortication are performed to manage conditions affecting the pleura (the membrane surrounding the lungs), such as pleural effusions, pneumothorax, or empyema.
8. Lung surgery: Thoracic surgeons perform procedures on the lungs, including lobectomy, segmentectomy, or pneumonectomy to treat lung cancer, benign tumors, or other lung diseases.
9. Tracheal surgery: This includes procedures to repair or reconstruct damaged trachea or remove tumors and growths in the airway.
10. Esophageal surgery: Collaborating with general surgeons, thoracic surgeons perform esophagectomy and other procedures to treat esophageal cancer, benign tumors, or other conditions affecting the esophagus.

'Leg length inequality' (LLIS) is a condition where there is a discrepancy in the lengths of an individual's lower extremities, specifically the bones of the thigh (femur) and/or the leg (tibia/fibula). This discrepancy can be congenital or acquired due to various causes such as fractures, infections, or surgical procedures. The inequality can lead to functional scoliosis, lower back pain, and other musculoskeletal issues. It is typically diagnosed through physical examination and imaging studies like X-rays, and may be treated with various methods including orthotics, shoe lifts, or in some cases, surgical intervention.

Ophthalmoplegia is a medical term that refers to the paralysis or weakness of the eye muscles, which can result in double vision (diplopia) or difficulty moving the eyes. It can be caused by various conditions, including nerve damage, muscle disorders, or neurological diseases such as myasthenia gravis or multiple sclerosis. Ophthalmoplegia can affect one or more eye muscles and can be partial or complete. Depending on the underlying cause, ophthalmoplegia may be treatable with medications, surgery, or other interventions.

Equipment design, in the medical context, refers to the process of creating and developing medical equipment and devices, such as surgical instruments, diagnostic machines, or assistive technologies. This process involves several stages, including:

1. Identifying user needs and requirements
2. Concept development and brainstorming
3. Prototyping and testing
4. Design for manufacturing and assembly
5. Safety and regulatory compliance
6. Verification and validation
7. Training and support

The goal of equipment design is to create safe, effective, and efficient medical devices that meet the needs of healthcare providers and patients while complying with relevant regulations and standards. The design process typically involves a multidisciplinary team of engineers, clinicians, designers, and researchers who work together to develop innovative solutions that improve patient care and outcomes.

Observer variation, also known as inter-observer variability or measurement agreement, refers to the difference in observations or measurements made by different observers or raters when evaluating the same subject or phenomenon. It is a common issue in various fields such as medicine, research, and quality control, where subjective assessments are involved.

In medical terms, observer variation can occur in various contexts, including:

1. Diagnostic tests: Different radiologists may interpret the same X-ray or MRI scan differently, leading to variations in diagnosis.
2. Clinical trials: Different researchers may have different interpretations of clinical outcomes or adverse events, affecting the consistency and reliability of trial results.
3. Medical records: Different healthcare providers may document medical histories, physical examinations, or treatment plans differently, leading to inconsistencies in patient care.
4. Pathology: Different pathologists may have varying interpretations of tissue samples or laboratory tests, affecting diagnostic accuracy.

Observer variation can be minimized through various methods, such as standardized assessment tools, training and calibration of observers, and statistical analysis of inter-rater reliability.

Failed Back Surgery Syndrome (FBSS) is not a formally recognized medical diagnosis, but rather a term that is used to describe the condition of patients who continue to experience chronic pain in the spine or legs after having undergone one or more spinal surgeries. FBSS does not necessarily mean that the surgery was performed incorrectly, but rather that it did not achieve the desired outcome of relieving the patient's pain.

The symptoms of FBSS can vary from person to person, but often include chronic pain in the back or legs, numbness or tingling sensations, muscle weakness, and decreased mobility. The exact cause of FBSS is not always clear, but it may be due to a variety of factors, such as nerve damage, scar tissue formation, or continued spinal instability.

Treatment for FBSS typically involves a multidisciplinary approach that may include medication, physical therapy, injections, and psychological support. In some cases, additional surgery may be recommended, but this is usually considered a last resort due to the risks involved and the fact that previous surgeries have not been successful.

Orthopedic equipment refers to devices or appliances used in the practice of orthopedics, which is a branch of medicine focused on the correction, support, and prevention of disorders, injuries, or deformities of the skeletal system, including bones, joints, ligaments, tendons, and muscles. These devices can be categorized into various types based on their function and application:

1. Mobility aids: Equipment that helps individuals with impaired mobility to move around more easily, such as walkers, crutches, canes, wheelchairs, and scooters.
2. Immobilization devices: Used to restrict movement of a specific body part to promote healing, prevent further injury, or provide support during rehabilitation, including casts, braces, splints, slings, and collars.
3. Prosthetics: Artificial limbs that replace missing body parts due to amputation, illness, or congenital defects, enabling individuals to perform daily activities and maintain independence.
4. Orthotics: Custom-made or off-the-shelf devices worn inside shoes or on the body to correct foot alignment issues, provide arch support, or alleviate pain in the lower extremities.
5. Rehabilitation equipment: Devices used during physical therapy sessions to improve strength, flexibility, balance, and coordination, such as resistance bands, exercise balls, balance boards, and weight training machines.
6. Surgical instruments: Specialized tools used by orthopedic surgeons during operations to repair fractures, replace joints, or correct deformities, including saws, drills, retractors, and screwdrivers.
7. Diagnostic equipment: Imaging devices that help healthcare professionals assess musculoskeletal conditions, such as X-ray machines, CT scanners, MRI machines, and ultrasound systems.

These various types of orthopedic equipment play a crucial role in the diagnosis, treatment, rehabilitation, and management of orthopedic disorders and injuries, enhancing patients' quality of life and functional abilities.

Esophageal atresia is a congenital condition in which the esophagus, the tube that connects the throat to the stomach, does not develop properly. In most cases, the upper esophagus ends in a pouch instead of connecting to the lower esophagus and stomach. This condition prevents food and liquids from reaching the stomach, leading to difficulty swallowing and feeding problems in newborn infants. Esophageal atresia often occurs together with a congenital defect called tracheoesophageal fistula, in which there is an abnormal connection between the esophagus and the windpipe (trachea).

The medical definition of 'Esophageal Atresia' is:

A congenital anomaly characterized by the absence of a normal connection between the upper esophagus and the stomach, resulting in the separation of the proximal and distal esophageal segments. The proximal segment usually ends in a blind pouch, while the distal segment may communicate with the trachea through a tracheoesophageal fistula. Esophageal atresia is often associated with other congenital anomalies and can cause serious complications if not diagnosed and treated promptly after birth.

Bone transplantation, also known as bone grafting, is a surgical procedure in which bone or bone-like material is transferred from one part of the body to another or from one person to another. The graft may be composed of cortical (hard outer portion) bone, cancellous (spongy inner portion) bone, or a combination of both. It can be taken from different sites in the same individual (autograft), from another individual of the same species (allograft), or from an animal source (xenograft). The purpose of bone transplantation is to replace missing bone, provide structural support, and stimulate new bone growth. This procedure is commonly used in orthopedic, dental, and maxillofacial surgeries to repair bone defects caused by trauma, tumors, or congenital conditions.

Intraoperative complications refer to any unforeseen problems or events that occur during the course of a surgical procedure, once it has begun and before it is completed. These complications can range from minor issues, such as bleeding or an adverse reaction to anesthesia, to major complications that can significantly impact the patient's health and prognosis.

Examples of intraoperative complications include:

1. Bleeding (hemorrhage) - This can occur due to various reasons such as injury to blood vessels or organs during surgery.
2. Infection - Surgical site infections can develop if the surgical area becomes contaminated during the procedure.
3. Anesthesia-related complications - These include adverse reactions to anesthesia, difficulty maintaining the patient's airway, or cardiovascular instability.
4. Organ injury - Accidental damage to surrounding organs can occur during surgery, leading to potential long-term consequences.
5. Equipment failure - Malfunctioning surgical equipment can lead to complications and compromise the safety of the procedure.
6. Allergic reactions - Patients may have allergies to certain medications or materials used during surgery, causing an adverse reaction.
7. Prolonged operative time - Complications may arise if a surgical procedure takes longer than expected, leading to increased risk of infection and other issues.

Intraoperative complications require prompt identification and management by the surgical team to minimize their impact on the patient's health and recovery.

Anthropometry is the scientific study of measurements and proportions of the human body. It involves the systematic measurement and analysis of various physical characteristics, such as height, weight, blood pressure, waist circumference, and other body measurements. These measurements are used in a variety of fields, including medicine, ergonomics, forensics, and fashion design, to assess health status, fitness level, or to design products and environments that fit the human body. In a medical context, anthropometry is often used to assess growth and development, health status, and disease risk factors in individuals and populations.

Prospective studies, also known as longitudinal studies, are a type of cohort study in which data is collected forward in time, following a group of individuals who share a common characteristic or exposure over a period of time. The researchers clearly define the study population and exposure of interest at the beginning of the study and follow up with the participants to determine the outcomes that develop over time. This type of study design allows for the investigation of causal relationships between exposures and outcomes, as well as the identification of risk factors and the estimation of disease incidence rates. Prospective studies are particularly useful in epidemiology and medical research when studying diseases with long latency periods or rare outcomes.

Surgical blood loss is the amount of blood that is lost during a surgical procedure. It can occur through various routes such as incisions, punctures or during the removal of organs or tissues. The amount of blood loss can vary widely depending on the type and complexity of the surgery being performed.

Surgical blood loss can be classified into three categories:

1. Insensible losses: These are small amounts of blood that are lost through the skin, respiratory tract, or gastrointestinal tract during surgery. They are not usually significant enough to cause any clinical effects.
2. Visible losses: These are larger amounts of blood that can be seen and measured directly during surgery. They may require transfusion or other interventions to prevent hypovolemia (low blood volume) and its complications.
3. Hidden losses: These are internal bleeding that cannot be easily seen or measured during surgery. They can occur in the abdominal cavity, retroperitoneal space, or other areas of the body. They may require further exploration or imaging studies to diagnose and manage.

Surgical blood loss can lead to several complications such as hypovolemia, anemia, coagulopathy (disorders of blood clotting), and organ dysfunction. Therefore, it is essential to monitor and manage surgical blood loss effectively to ensure optimal patient outcomes.

Equipment failure is a term used in the medical field to describe the malfunction or breakdown of medical equipment, devices, or systems that are essential for patient care. This can include simple devices like syringes and thermometers, as well as complex machines such as ventilators, infusion pumps, and imaging equipment.

Equipment failure can have serious consequences for patients, including delayed or inappropriate treatment, injury, or even death. It is therefore essential that medical equipment is properly maintained, tested, and repaired to ensure its safe and effective operation.

There are many potential causes of equipment failure, including:

* Wear and tear from frequent use
* Inadequate cleaning or disinfection
* Improper handling or storage
* Power supply issues
* Software glitches or bugs
* Mechanical failures or defects
* Human error or misuse

To prevent equipment failure, healthcare facilities should have established policies and procedures for the acquisition, maintenance, and disposal of medical equipment. Staff should be trained in the proper use and handling of equipment, and regular inspections and testing should be performed to identify and address any potential issues before they lead to failure.

Intervertebral disc displacement, also known as a slipped disc or herniated disc, is a medical condition where the inner, softer material (nucleus pulposus) of the intervertebral disc bulges or ruptures through its outer, tougher ring (annulus fibrosus). This can put pressure on nearby nerves and cause pain, numbness, tingling, or weakness in the affected area, often in the lower back or neck. The displacement may also lead to inflammation and irritation of the surrounding spinal structures, further exacerbating the symptoms. The condition is typically caused by age-related wear and tear (degenerative disc disease) or sudden trauma.

Lameness in animals refers to an alteration in the animal's normal gait or movement, which is often caused by pain, injury, or disease affecting the locomotor system. This can include structures such as bones, joints, muscles, tendons, and ligaments. The severity of lameness can vary from subtle to non-weight bearing, and it can affect one or more limbs.

Lameness can have various causes, including trauma, infection, degenerative diseases, congenital defects, and neurological disorders. In order to diagnose and treat lameness in animals, a veterinarian will typically perform a physical examination, observe the animal's gait and movement, and may use diagnostic imaging techniques such as X-rays or ultrasound to identify the underlying cause. Treatment for lameness can include medication, rest, physical therapy, surgery, or a combination of these approaches.

Surgical equipment refers to the specialized tools and instruments used by medical professionals during surgical procedures. These devices are designed to assist in various aspects of surgery, such as cutting, grasping, retraction, clamping, and suturing. Surgical equipment can be categorized into several types based on their function and use:

1. Cutting instruments: These include scalpels, scissors, and surgical blades designed to cut through tissues with precision and minimal trauma.

2. Grasping forceps: Forceps are used to hold, manipulate, or retrieve tissue, organs, or other surgical tools. Examples include Babcock forceps, Kelly forceps, and Allis tissue forceps.

3. Retractors: These devices help to expose deeper structures by holding open body cavities or tissues during surgery. Common retractors include Weitlaner retractors, Army-Navy retractors, and self-retaining retractors like the Bookwalter system.

4. Clamps: Used for occluding blood vessels, controlling bleeding, or approximating tissue edges before suturing. Examples of clamps are hemostats, bulldog clips, and Satinsky clamps.

5. Suction devices: These tools help remove fluids, debris, and smoke from the surgical site, improving visibility for the surgeon. Examples include Yankauer suctions and Frazier tip suctions.

6. Needle holders: Specialized forceps designed to hold suture needles securely during the process of suturing or approximating tissue edges.

7. Surgical staplers: Devices that place linear staple lines in tissues, used for quick and efficient closure of surgical incisions or anastomoses (joining two structures together).

8. Cautery devices: Electrosurgical units that use heat generated by electrical current to cut tissue and coagulate bleeding vessels.

9. Implants and prosthetics: Devices used to replace or reinforce damaged body parts, such as artificial joints, heart valves, or orthopedic implants.

10. Monitoring and navigation equipment: Advanced tools that provide real-time feedback on patient physiology, surgical site anatomy, or instrument positioning during minimally invasive procedures.

These are just a few examples of the diverse range of instruments and devices used in modern surgery. The choice of tools depends on various factors, including the type of procedure, patient characteristics, and surgeon preference.

A laminectomy is a surgical procedure that involves the removal of the lamina, which is the back part of the vertebra that covers the spinal canal. This procedure is often performed to relieve pressure on the spinal cord or nerves caused by conditions such as herniated discs, spinal stenosis, or tumors. By removing the lamina, the surgeon can access the affected area and alleviate the compression on the spinal cord or nerves, thereby reducing pain, numbness, or weakness in the back, legs, or arms.

Laminectomy may be performed as a standalone procedure or in combination with other surgical techniques such as discectomy, foraminotomy, or spinal fusion. The specific approach and extent of the surgery will depend on the patient's individual condition and symptoms.

Maximal Voluntary Ventilation (MVV) is a measure of the maximum amount of air that can be voluntarily breathed in and out of the lungs in one minute. It is often used as a clinical assessment to evaluate respiratory function and lung capacity. The test involves breathing as deeply and quickly as possible for a period of time, usually 12-15 breaths, and the total volume of air exhaled during that time is measured. This value is then extrapolated to one minute to determine the MVV. It is typically expressed in liters per minute (L/min).

MVV provides information about a person's overall respiratory muscle strength and endurance, as well as their ability to ventilate their lungs effectively. Reduced MVV values may indicate restrictive or obstructive lung diseases, such as COPD or pulmonary fibrosis, or neuromuscular disorders that affect the respiratory muscles. However, MVV should be interpreted in conjunction with other clinical data and tests to make a definitive diagnosis.

Disability Evaluation is the process of determining the nature and extent of a person's functional limitations or impairments, and assessing their ability to perform various tasks and activities in order to determine eligibility for disability benefits or accommodations. This process typically involves a medical examination and assessment by a licensed healthcare professional, such as a physician or psychologist, who evaluates the individual's symptoms, medical history, laboratory test results, and functional abilities. The evaluation may also involve input from other professionals, such as vocational experts, occupational therapists, or speech-language pathologists, who can provide additional information about the person's ability to perform specific tasks and activities in a work or daily living context. Based on this information, a determination is made about whether the individual meets the criteria for disability as defined by the relevant governing authority, such as the Social Security Administration or the Americans with Disabilities Act.

The torso refers to the central part of the human body, which is composed of the spine, ribcage, and the abdomen. It does not include the head, neck, arms, or legs. In anatomical terms, it is often used to describe the area between the neck and the pelvis.

Spinal cord neoplasms refer to abnormal growths or tumors within the spinal cord. These can be benign (non-cancerous) or malignant (cancerous). They originate from the cells within the spinal cord itself (primary tumors), or they may spread to the spinal cord from other parts of the body (metastatic tumors). Spinal cord neoplasms can cause various symptoms depending on their location and size, including back pain, neurological deficits, and even paralysis. Treatment options include surgery, radiation therapy, and chemotherapy.

Neurosurgical procedures are operations that are performed on the brain, spinal cord, and peripheral nerves. These procedures are typically carried out by neurosurgeons, who are medical doctors with specialized training in the diagnosis and treatment of disorders of the nervous system. Neurosurgical procedures can be used to treat a wide range of conditions, including traumatic injuries, tumors, aneurysms, vascular malformations, infections, degenerative diseases, and congenital abnormalities.

Some common types of neurosurgical procedures include:

* Craniotomy: A procedure in which a bone flap is temporarily removed from the skull to gain access to the brain. This type of procedure may be performed to remove a tumor, repair a blood vessel, or relieve pressure on the brain.
* Spinal fusion: A procedure in which two or more vertebrae in the spine are fused together using bone grafts and metal hardware. This is often done to stabilize the spine and alleviate pain caused by degenerative conditions or spinal deformities.
* Microvascular decompression: A procedure in which a blood vessel that is causing pressure on a nerve is repositioned or removed. This type of procedure is often used to treat trigeminal neuralgia, a condition that causes severe facial pain.
* Deep brain stimulation: A procedure in which electrodes are implanted in specific areas of the brain and connected to a battery-operated device called a neurostimulator. The neurostimulator sends electrical impulses to the brain to help alleviate symptoms of movement disorders such as Parkinson's disease or dystonia.
* Stereotactic radiosurgery: A non-invasive procedure that uses focused beams of radiation to treat tumors, vascular malformations, and other abnormalities in the brain or spine. This type of procedure is often used for patients who are not good candidates for traditional surgery due to age, health status, or location of the lesion.

Neurosurgical procedures can be complex and require a high degree of skill and expertise. Patients considering neurosurgical treatment should consult with a qualified neurosurgeon to discuss their options and determine the best course of action for their individual situation.

Growth charts are standardized tools used in pediatrics to plot and track the growth of children from birth to age 20. These charts typically plot a child's height, weight, head circumference (in infants), and body mass index (BMI) against established norms based on large population studies. The charts provide a visual representation of a child's growth pattern over time, allowing healthcare providers to assess if the child is growing properly. They are used to identify any deviations from normal growth patterns which may indicate underlying health issues. The World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) both provide standard growth charts for international and US use respectively.

Dysostosis is a term used to describe a group of genetic disorders that are characterized by abnormal development and formation of one or more bones in the body. The condition is typically present at birth (congenital) and can affect any bone, but it most commonly involves the bones of the skull, face, hands, and feet.

The term "dysostosis" comes from the Greek words "dys," meaning difficult or abnormal, and "osteon," meaning bone. Dysostoses are usually caused by mutations in specific genes that regulate bone development. These genetic changes can be inherited from one or both parents or can occur spontaneously during fetal development.

There are many different types of dysostoses, each with its own set of symptoms and characteristics. Some common examples include:

1. Cleidocranial Dysplasia: This is a rare genetic disorder that affects the development of the skull and collarbones (cleido). People with cleidocranial dysplasia may have a larger than normal head, wide-set eyes, a prominent forehead, and underdeveloped or missing collarbones.
2. Acrocephalopolysyndactyly Type II: Also known as ACPS II or Greig cephalopolysyndactyly syndrome, this disorder is characterized by a pointed skull (acrocephaly), extra fingers and toes (polydactyly), and wide-set eyes.
3. Osteogenesis Imperfecta: This is a group of genetic disorders that affect the body's production of collagen, a protein that helps to strengthen bones. People with osteogenesis imperfecta have fragile bones that break easily, often as a result of minor trauma.
4. Diastrophic Dysplasia: This is a rare genetic disorder that affects the development of the bones and cartilage in the body. People with diastrophic dysplasia may have short limbs, a deformed spine, and a characteristic "hitchhiker's thumb" appearance.
5. Thanatophoric Dysplasia: This is a severe genetic disorder that affects the development of the bones in the body. People with thanatophoric dysplasia have very short limbs, a small chest, and a deformed skull. The condition is often fatal in infancy or early childhood.

These are just a few examples of the many different types of skeletal dysplasias that exist. While some forms of these disorders can be managed with medical treatment and therapy, others may require surgery or other interventions to help improve quality of life. In some cases, genetic counseling and testing may be recommended for individuals who are considering starting a family and have a history of skeletal dysplasia in their family.

An abnormal reflex in a medical context refers to an involuntary and exaggerated response or lack of response to a stimulus that is not expected in the normal physiological range. These responses can be indicative of underlying neurological disorders or damage to the nervous system. Examples include hyperreflexia (overactive reflexes) and hyporeflexia (underactive reflexes). The assessment of reflexes is an important part of a physical examination, as it can provide valuable information about the functioning of the nervous system.

Arthrogryposis is a medical term that describes a condition characterized by the presence of multiple joint contractures at birth. A contracture occurs when the range of motion in a joint is limited, making it difficult or impossible to move the joint through its full range of motion. In arthrogryposis, these contractures are present in two or more areas of the body.

The term "arthrogryposis" comes from two Greek words: "arthro," meaning joint, and "gyros," meaning curved or bent. Therefore, arthrogryposis literally means "curving of the joints."

There are many different types of arthrogryposis, each with its own specific set of symptoms and causes. However, in general, arthrogryposis is caused by decreased fetal movement during pregnancy, which can be due to a variety of factors such as genetic mutations, nervous system abnormalities, or environmental factors that restrict fetal movement.

Treatment for arthrogryposis typically involves a combination of physical therapy, bracing, and surgery to help improve joint mobility and function. The prognosis for individuals with arthrogryposis varies depending on the severity and type of contractures present, as well as the underlying cause of the condition.

Arthrodesis is a surgical procedure to fuse together the bones of a joint, in order to restrict its movement and provide stability. This procedure is typically performed when a joint has been severely damaged by injury, arthritis, or other conditions, and non-surgical treatments have failed to relieve symptoms such as pain and instability.

During the surgery, the cartilage that normally cushions the ends of the bones is removed, and the bones are realigned and held in place with hardware such as plates, screws, or rods. Over time, the bones grow together, forming a solid fusion that restricts joint motion.

Arthrodesis can be performed on various joints throughout the body, including the spine, wrist, ankle, and knee. While this procedure can provide significant pain relief and improve function, it does limit the range of motion in the fused joint, which may impact mobility and daily activities. Therefore, arthrodesis is typically considered a last resort when other treatments have failed.

An abdominal reflex is a withdrawal response that occurs when the skin in the lower abdomen is stimulated, leading to contraction of the muscles in the same side of the abdomen. This reflex is mediated by the T10-L1 spinal cord segments and is typically tested during a physical examination to assess the integrity of the nervous system. A decreased or absent abdominal reflex may indicate damage to the peripheral nerves, spinal cord, or brain.

Titanium is not a medical term, but rather a chemical element (symbol Ti, atomic number 22) that is widely used in the medical field due to its unique properties. Medically, it is often referred to as a biocompatible material used in various medical applications such as:

1. Orthopedic implants: Titanium and its alloys are used for making joint replacements (hips, knees, shoulders), bone plates, screws, and rods due to their high strength-to-weight ratio, excellent corrosion resistance, and biocompatibility.
2. Dental implants: Titanium is also commonly used in dental applications like implants, crowns, and bridges because of its ability to osseointegrate, or fuse directly with bone tissue, providing a stable foundation for replacement teeth.
3. Cardiovascular devices: Titanium alloys are used in the construction of heart valves, pacemakers, and other cardiovascular implants due to their non-magnetic properties, which prevent interference with magnetic resonance imaging (MRI) scans.
4. Medical instruments: Due to its resistance to corrosion and high strength, titanium is used in the manufacturing of various medical instruments such as surgical tools, needles, and catheters.

In summary, Titanium is a chemical element with unique properties that make it an ideal material for various medical applications, including orthopedic and dental implants, cardiovascular devices, and medical instruments.

"Body height" is a measure of the vertical length of a person's body from the top of their head to the bottom of their feet. It is typically measured in units such as centimeters (cm) or inches (in). In medical settings, body height is often used as a basic anthropometric measurement to assess overall health status, growth and development, nutritional status, and aging-related changes.

There are different methods for measuring body height, but the most common one involves having the person stand upright against a vertical surface (such as a wall or a stadiometer) with their heels, buttocks, shoulders, and head touching the surface. The measurement is taken at the point where the top of the person's head meets the surface.

Body height can be influenced by various factors, including genetics, nutrition, health status, and environmental conditions. Changes in body height over time can provide important insights into a person's health trajectory and potential health risks. For example, a significant decrease in body height may indicate bone loss or spinal compression, while a rapid increase in height during childhood or adolescence may suggest optimal growth and development.

In medical terms, the hip is a ball-and-socket joint where the rounded head of the femur (thigh bone) fits into the cup-shaped socket, also known as the acetabulum, of the pelvis. This joint allows for a wide range of movement in the lower extremities and supports the weight of the upper body during activities such as walking, running, and jumping. The hip joint is surrounded by strong ligaments, muscles, and tendons that provide stability and enable proper functioning.

Neurofibromatosis 1 (NF1) is a genetic disorder that affects the development and growth of nerve tissue. It's also known as von Recklinghausen disease. NF1 is characterized by the growth of non-cancerous tumors on the nerves, as well as skin and bone abnormalities.

The symptoms of Neurofibromatosis 1 can vary widely, even among members of the same family. Some common features include:

* Multiple café au lait spots (flat, light brown patches on the skin)
* Freckles in the underarms and groin area
* Benign growths on or under the skin called neurofibromas
* Larger, more complex tumors called plexiform neurofibromas
* Optic gliomas (tumors that form on the optic nerve)
* Distinctive bone abnormalities, such as a curved spine (scoliosis) or an enlarged head (macrocephaly)
* Learning disabilities and behavioral problems

Neurofibromatosis 1 is caused by mutations in the NF1 gene, which provides instructions for making a protein called neurofibromin. This protein helps regulate cell growth and division. When the NF1 gene is mutated, the production of neurofibromin is reduced or absent, leading to uncontrolled cell growth and the development of tumors.

NF1 is an autosomal dominant disorder, which means that a person has a 50% chance of inheriting the mutated gene from an affected parent. However, about half of all cases are the result of new mutations in the NF1 gene, and occur in people with no family history of the disorder.

There is currently no cure for Neurofibromatosis 1, but treatments are available to manage the symptoms and complications of the disease. These may include medications to control pain or reduce the size of tumors, surgery to remove tumors or correct bone abnormalities, and physical therapy to improve mobility and strength. Regular monitoring by a healthcare team experienced in treating Neurofibromatosis 1 is also important to detect any changes in the condition and provide appropriate care.

Melatonin is a hormone that is produced by the pineal gland in the brain. It helps regulate sleep-wake cycles and is often referred to as the "hormone of darkness" because its production is stimulated by darkness and inhibited by light. Melatonin plays a key role in synchronizing the circadian rhythm, the body's internal clock that regulates various biological processes over a 24-hour period.

Melatonin is primarily released at night, and its levels in the blood can rise and fall in response to changes in light and darkness in an individual's environment. Supplementing with melatonin has been found to be helpful in treating sleep disorders such as insomnia, jet lag, and delayed sleep phase syndrome. It may also have other benefits, including antioxidant properties and potential uses in the treatment of certain neurological conditions.

It is important to note that while melatonin supplements are available over-the-counter in many countries, they should still be used under the guidance of a healthcare professional, as their use can have potential side effects and interactions with other medications.

Surgical hemostasis refers to the methods and techniques used during surgical procedures to stop bleeding or prevent hemorrhage. This can be achieved through various means, including the use of surgical instruments such as clamps, ligatures, or staples to physically compress blood vessels and stop the flow of blood. Electrosurgical tools like cautery may also be used to coagulate and seal off bleeding vessels using heat. Additionally, topical hemostatic agents can be applied to promote clotting and control bleeding in wounded tissues. Effective surgical hemostasis is crucial for ensuring a successful surgical outcome and minimizing the risk of complications such as excessive blood loss, infection, or delayed healing.

I'm sorry for any confusion, but "Poland" is not a medical term. It is a country in Central Europe. If you have any questions about medical conditions or terminology, I would be happy to help answer those!

A case-control study is an observational research design used to identify risk factors or causes of a disease or health outcome. In this type of study, individuals with the disease or condition (cases) are compared with similar individuals who do not have the disease or condition (controls). The exposure history or other characteristics of interest are then compared between the two groups to determine if there is an association between the exposure and the disease.

Case-control studies are often used when it is not feasible or ethical to conduct a randomized controlled trial, as they can provide valuable insights into potential causes of diseases or health outcomes in a relatively short period of time and at a lower cost than other study designs. However, because case-control studies rely on retrospective data collection, they are subject to biases such as recall bias and selection bias, which can affect the validity of the results. Therefore, it is important to carefully design and conduct case-control studies to minimize these potential sources of bias.

A tracheoesophageal fistula (TEF) is an abnormal connection between the trachea (windpipe) and the esophagus (tube that carries food from the mouth to the stomach). This congenital anomaly is usually present at birth and can vary in size and location. It can cause complications such as respiratory distress, feeding difficulties, and recurrent lung infections. TEF is often treated surgically to separate the trachea and esophagus and restore their normal functions.

Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It is characterized by bones that break easily, often from little or no apparent cause. This happens because the body produces an insufficient amount of collagen or poor quality collagen, which are crucial for the formation of healthy bones.

The severity of OI can vary greatly, even within the same family. Some people with OI have only a few fractures in their lifetime while others may have hundreds. Other symptoms can include blue or gray sclera (the white part of the eye), hearing loss, short stature, curved or bowed bones, loose joints, and a triangular face shape.

There are several types of OI, each caused by different genetic mutations. Most types of OI are inherited in an autosomal dominant pattern, meaning only one copy of the altered gene is needed to cause the condition. However, some types are inherited in an autosomal recessive pattern, which means that two copies of the altered gene must be present for the condition to occur.

There is no cure for OI, but treatment can help manage symptoms and prevent complications. Treatment may include medication to strengthen bones, physical therapy, bracing, and surgery.

Paralysis is a loss of muscle function in part or all of your body. It can be localized, affecting only one specific area, or generalized, impacting multiple areas or even the entire body. Paralysis often occurs when something goes wrong with the way messages pass between your brain and muscles. In most cases, paralysis is caused by damage to the nervous system, especially the spinal cord. Other causes include stroke, trauma, infections, and various neurological disorders.

It's important to note that paralysis doesn't always mean a total loss of movement or feeling. Sometimes, it may just cause weakness or numbness in the affected area. The severity and extent of paralysis depend on the underlying cause and the location of the damage in the nervous system.

A gait disorder is a disturbance in the ability to walk that can't be attributed to physical disabilities such as weakness or paralysis. Neurologic gait disorders are those specifically caused by underlying neurological conditions. These disorders can result from damage to the brain, spinal cord, or peripheral nerves that disrupts communication between the muscles and the brain.

Neurologic gait disorders can present in various ways, including:

1. **Spastic Gait:** This is a stiff, foot-dragging walk caused by increased muscle tone (hypertonia) and stiffness (spasticity). It's often seen in conditions like cerebral palsy or multiple sclerosis.

2. **Ataxic Gait:** This is a broad-based, unsteady, and irregular walk caused by damage to the cerebellum, which affects balance and coordination. Conditions such as cerebellar atrophy or stroke can cause this type of gait disorder.

3. **Parkinsonian Gait:** This is a shuffling walk with small steps, flexed knees, and difficulty turning. It's often seen in Parkinson's disease.

4. **Neuropathic Gait:** This is a high-stepping walk caused by foot drop (difficulty lifting the front part of the foot), which results from damage to the peripheral nerves. Conditions such as diabetic neuropathy or Guillain-Barre syndrome can cause this type of gait disorder.

5. **Choreic Gait:** This is an irregular, dance-like walk caused by involuntary movements (chorea) seen in conditions like Huntington's disease.

6. **Mixed Gait:** Sometimes, a person may exhibit elements of more than one type of gait disorder.

The specific type of gait disorder can provide important clues about the underlying neurological condition and help guide diagnosis and treatment.

In anatomical terms, the shoulder refers to the complex joint of the human body that connects the upper limb to the trunk. It is formed by the union of three bones: the clavicle (collarbone), scapula (shoulder blade), and humerus (upper arm bone). The shoulder joint is a ball-and-socket type of synovial joint, allowing for a wide range of movements such as flexion, extension, abduction, adduction, internal rotation, and external rotation.

The shoulder complex includes not only the glenohumeral joint but also other structures that contribute to its movement and stability, including:

1. The acromioclavicular (AC) joint: where the clavicle meets the acromion process of the scapula.
2. The coracoclavicular (CC) ligament: connects the coracoid process of the scapula to the clavicle, providing additional stability to the AC joint.
3. The rotator cuff: a group of four muscles (supraspinatus, infraspinatus, teres minor, and subscapularis) that surround and reinforce the shoulder joint, contributing to its stability and range of motion.
4. The biceps tendon: originates from the supraglenoid tubercle of the scapula and passes through the shoulder joint, helping with flexion, supination, and stability.
5. Various ligaments and capsular structures that provide additional support and limit excessive movement in the shoulder joint.

The shoulder is a remarkable joint due to its wide range of motion, but this also makes it susceptible to injuries and disorders such as dislocations, subluxations, sprains, strains, tendinitis, bursitis, and degenerative conditions like osteoarthritis. Proper care, exercise, and maintenance are essential for maintaining shoulder health and function throughout one's life.

Developmental bone diseases are a group of medical conditions that affect the growth and development of bones. These diseases are present at birth or develop during childhood and adolescence, when bones are growing rapidly. They can result from genetic mutations, hormonal imbalances, or environmental factors such as poor nutrition.

Some examples of developmental bone diseases include:

1. Osteogenesis imperfecta (OI): Also known as brittle bone disease, OI is a genetic disorder that affects the body's production of collagen, a protein necessary for healthy bones. People with OI have fragile bones that break easily and may also experience other symptoms such as blue sclerae (whites of the eyes), hearing loss, and joint laxity.
2. Achondroplasia: This is the most common form of dwarfism, caused by a genetic mutation that affects bone growth. People with achondroplasia have short limbs and a large head relative to their body size.
3. Rickets: A condition caused by vitamin D deficiency or an inability to absorb or use vitamin D properly. This leads to weak, soft bones that can bow or bend easily, particularly in children.
4. Fibrous dysplasia: A rare bone disorder where normal bone is replaced with fibrous tissue, leading to weakened bones and deformities.
5. Scoliosis: An abnormal curvature of the spine that can develop during childhood or adolescence. While not strictly a developmental bone disease, scoliosis can be caused by various underlying conditions such as cerebral palsy, muscular dystrophy, or spina bifida.

Treatment for developmental bone diseases varies depending on the specific condition and its severity. Treatment may include medication, physical therapy, bracing, or surgery to correct deformities and improve function. Regular follow-up with a healthcare provider is essential to monitor growth, manage symptoms, and prevent complications.

I'm sorry for any confusion, but "Utah" is not a medical term or concept. It is a geographical location, being the 45th state admitted to the United States of America. If you have any questions related to medical topics, I would be happy to try and help answer those for you!

Reproducibility of results in a medical context refers to the ability to obtain consistent and comparable findings when a particular experiment or study is repeated, either by the same researcher or by different researchers, following the same experimental protocol. It is an essential principle in scientific research that helps to ensure the validity and reliability of research findings.

In medical research, reproducibility of results is crucial for establishing the effectiveness and safety of new treatments, interventions, or diagnostic tools. It involves conducting well-designed studies with adequate sample sizes, appropriate statistical analyses, and transparent reporting of methods and findings to allow other researchers to replicate the study and confirm or refute the results.

The lack of reproducibility in medical research has become a significant concern in recent years, as several high-profile studies have failed to produce consistent findings when replicated by other researchers. This has led to increased scrutiny of research practices and a call for greater transparency, rigor, and standardization in the conduct and reporting of medical research.

The postoperative period is the time following a surgical procedure during which the patient's response to the surgery and anesthesia is monitored, and any complications or adverse effects are managed. This period can vary in length depending on the type of surgery and the individual patient's needs, but it typically includes the immediate recovery phase in the post-anesthesia care unit (PACU) or recovery room, as well as any additional time spent in the hospital for monitoring and management of pain, wound healing, and other aspects of postoperative care.

The goals of postoperative care are to ensure the patient's safety and comfort, promote optimal healing and rehabilitation, and minimize the risk of complications such as infection, bleeding, or other postoperative issues. The specific interventions and treatments provided during this period will depend on a variety of factors, including the type and extent of surgery performed, the patient's overall health and medical history, and any individualized care plans developed in consultation with the patient and their healthcare team.

A decompressive craniectomy is a neurosurgical procedure in which a portion of the skull is removed to allow the swollen brain to expand and reduce intracranial pressure. This surgical intervention is typically performed as a last resort in cases where other treatments for increased intracranial pressure, such as hyperosmolar therapy or drainage of cerebrospinal fluid, have been unsuccessful.

During the procedure, the surgeon creates an opening in the skull (craniectomy) and removes a piece of bone (bone flap). This exposes the brain and creates additional space for it to expand without being compressed by the rigid skull. The dura mater, the outermost protective layer surrounding the brain, may also be opened to provide further room for brain swelling.

Once the swelling has subsided, a second procedure known as cranioplasty is performed to replace the removed bone flap or use an artificial implant to restore the skull's integrity and protect the underlying brain tissue. The timing of cranioplasty can vary depending on individual patient factors and clinical conditions.

Decompressive craniectomy is most commonly used in the management of traumatic brain injuries, stroke-induced malignant cerebral edema, and intracranial hypertension due to various causes, such as infection or inflammation. While this procedure can be lifesaving in some cases, it may also lead to complications like seizures, hydrocephalus, or neurological deficits. Therefore, the decision to perform a decompressive craniectomy should be made carefully and on an individual basis, considering both the potential benefits and risks.

Respiratory insufficiency is a condition characterized by the inability of the respiratory system to maintain adequate gas exchange, resulting in an inadequate supply of oxygen and/or removal of carbon dioxide from the body. This can occur due to various causes, such as lung diseases (e.g., chronic obstructive pulmonary disease, pneumonia), neuromuscular disorders (e.g., muscular dystrophy, spinal cord injury), or other medical conditions that affect breathing mechanics and/or gas exchange.

Respiratory insufficiency can manifest as hypoxemia (low oxygen levels in the blood) and/or hypercapnia (high carbon dioxide levels in the blood). Symptoms of respiratory insufficiency may include shortness of breath, rapid breathing, fatigue, confusion, and in severe cases, loss of consciousness or even death. Treatment depends on the underlying cause and severity of the condition and may include oxygen therapy, mechanical ventilation, medications, and/or other supportive measures.

A reoperation is a surgical procedure that is performed again on a patient who has already undergone a previous operation for the same or related condition. Reoperations may be required due to various reasons, such as inadequate initial treatment, disease recurrence, infection, or complications from the first surgery. The nature and complexity of a reoperation can vary widely depending on the specific circumstances, but it often carries higher risks and potential complications compared to the original operation.

School health services refer to the health programs and services provided within schools by qualified healthcare professionals or specialists. These services aim to improve the overall well-being, academic success, and development of students by addressing both their physical and mental health needs. Examples of school health services include:

1. Health screenings: Routine vision, hearing, dental, and other health screenings to identify any potential issues early on.
2. Immunizations: Ensuring students are up-to-date with required immunizations and providing education about the importance of vaccinations.
3. Chronic disease management: Helping students manage chronic conditions such as asthma, diabetes, or epilepsy through individualized care plans and coordination with healthcare providers.
4. Mental health services: Providing counseling, therapy, and support for students dealing with emotional or behavioral challenges, including anxiety, depression, or trauma.
5. Health education: Teaching students about various health topics, such as nutrition, hygiene, sexual health, substance abuse prevention, and safety practices.
6. Case management: Coordinating care and providing resources for students with complex medical needs or social determinants of health challenges.
7. First aid and emergency care: Providing immediate medical attention in case of injuries or illnesses that occur during school hours.
8. Referrals to community resources: Connecting students and families with local healthcare providers, support services, and other resources as needed.

The goal of school health services is to create a safe, healthy, and supportive learning environment that promotes the overall well-being of all students.

Spinal stenosis is a narrowing of the spinal canal or the neural foramina (the openings through which nerves exit the spinal column), typically in the lower back (lumbar) or neck (cervical) regions. This can put pressure on the spinal cord and/or nerve roots, causing pain, numbness, tingling, or weakness in the affected areas, often in the legs, arms, or hands. It's most commonly caused by age-related wear and tear, but can also be due to degenerative changes, herniated discs, tumors, or spinal injuries.

The ilium is the largest and broadest of the three parts that make up the hip bone or coxal bone. It is the uppermost portion of the pelvis and forms the side of the waist. The ilium has a curved, fan-like shape and articulates with the sacrum at the back to form the sacroiliac joint. The large, concave surface on the top of the ilium is called the iliac crest, which can be felt as a prominent ridge extending from the front of the hip to the lower back. This region is significant in orthopedics and physical examinations for its use in assessing various medical conditions and performing certain maneuvers during the physical examination.

"Age factors" refer to the effects, changes, or differences that age can have on various aspects of health, disease, and medical care. These factors can encompass a wide range of issues, including:

1. Physiological changes: As people age, their bodies undergo numerous physical changes that can affect how they respond to medications, illnesses, and medical procedures. For example, older adults may be more sensitive to certain drugs or have weaker immune systems, making them more susceptible to infections.
2. Chronic conditions: Age is a significant risk factor for many chronic diseases, such as heart disease, diabetes, cancer, and arthritis. As a result, age-related medical issues are common and can impact treatment decisions and outcomes.
3. Cognitive decline: Aging can also lead to cognitive changes, including memory loss and decreased decision-making abilities. These changes can affect a person's ability to understand and comply with medical instructions, leading to potential complications in their care.
4. Functional limitations: Older adults may experience physical limitations that impact their mobility, strength, and balance, increasing the risk of falls and other injuries. These limitations can also make it more challenging for them to perform daily activities, such as bathing, dressing, or cooking.
5. Social determinants: Age-related factors, such as social isolation, poverty, and lack of access to transportation, can impact a person's ability to obtain necessary medical care and affect their overall health outcomes.

Understanding age factors is critical for healthcare providers to deliver high-quality, patient-centered care that addresses the unique needs and challenges of older adults. By taking these factors into account, healthcare providers can develop personalized treatment plans that consider a person's age, physical condition, cognitive abilities, and social circumstances.

Patient satisfaction is a concept in healthcare quality measurement that reflects the patient's perspective and evaluates their experience with the healthcare services they have received. It is a multidimensional construct that includes various aspects such as interpersonal mannerisms of healthcare providers, technical competence, accessibility, timeliness, comfort, and communication.

Patient satisfaction is typically measured through standardized surveys or questionnaires that ask patients to rate their experiences on various aspects of care. The results are often used to assess the quality of care provided by healthcare organizations, identify areas for improvement, and inform policy decisions. However, it's important to note that patient satisfaction is just one aspect of healthcare quality and should be considered alongside other measures such as clinical outcomes and patient safety.

Spinal neoplasms refer to abnormal growths or tumors found within the spinal column, which can be benign (non-cancerous) or malignant (cancerous). These tumors can originate in the spine itself, called primary spinal neoplasms, or they can spread to the spine from other parts of the body, known as secondary or metastatic spinal neoplasms. Spinal neoplasms can cause various symptoms, such as back pain, neurological deficits, and even paralysis, depending on their location and size. Early diagnosis and treatment are crucial to prevent or minimize long-term complications and improve the patient's prognosis.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Iatrogenic disease refers to any condition or illness that is caused, directly or indirectly, by medical treatment or intervention. This can include adverse reactions to medications, infections acquired during hospitalization, complications from surgical procedures, or injuries caused by medical equipment. It's important to note that iatrogenic diseases are unintended and often preventable with proper care and precautions.

Consanguinity is a medical and genetic term that refers to the degree of genetic relationship between two individuals who share common ancestors. Consanguineous relationships exist when people are related by blood, through a common ancestor or siblings who have children together. The closer the relationship between the two individuals, the higher the degree of consanguinity.

The degree of consanguinity is typically expressed as a percentage or fraction, with higher values indicating a closer genetic relationship. For example, first-degree relatives, such as parents and children or full siblings, share approximately 50% of their genes and have a consanguinity coefficient of 0.25 (or 25%).

Consanguinity can increase the risk of certain genetic disorders and birth defects in offspring due to the increased likelihood of sharing harmful recessive genes. The risks depend on the degree of consanguinity, with closer relationships carrying higher risks. It is important for individuals who are planning to have children and have a history of consanguinity to consider genetic counseling and testing to assess their risk of passing on genetic disorders.

A lung is a pair of spongy, elastic organs in the chest that work together to enable breathing. They are responsible for taking in oxygen and expelling carbon dioxide through the process of respiration. The left lung has two lobes, while the right lung has three lobes. The lungs are protected by the ribcage and are covered by a double-layered membrane called the pleura. The trachea divides into two bronchi, which further divide into smaller bronchioles, leading to millions of tiny air sacs called alveoli, where the exchange of gases occurs.

Computer-assisted radiographic image interpretation is the use of computer algorithms and software to assist and enhance the interpretation and analysis of medical images produced by radiography, such as X-rays, CT scans, and MRI scans. The computer-assisted system can help identify and highlight certain features or anomalies in the image, such as tumors, fractures, or other abnormalities, which may be difficult for the human eye to detect. This technology can improve the accuracy and speed of diagnosis, and may also reduce the risk of human error. It's important to note that the final interpretation and diagnosis is always made by a qualified healthcare professional, such as a radiologist, who takes into account the computer-assisted analysis in conjunction with their clinical expertise and knowledge.

"Poecilia" is not a medical term, but a biological genus name. It belongs to the family Poeciliidae and includes several species of small freshwater fish commonly known as mollies, guppies, and swordtails. These fish are often kept in aquariums as pets. They are livebearers, which means they give birth to live young rather than laying eggs.

A "learning curve" is not a medical term per se, but rather a general concept that is used in various fields including medicine. It refers to the process of acquiring new skills or knowledge in a specific task or activity, and the improvement in performance that comes with experience and practice over time.

In a medical context, a learning curve may refer to the rate at which healthcare professionals acquire proficiency in a new procedure, technique, or technology. It can also describe how quickly patients learn to manage their own health conditions or treatments. The term is often used to evaluate the effectiveness of training programs and to identify areas where additional education or practice may be necessary.

It's important to note that individuals may have different learning curves depending on factors such as prior experience, innate abilities, motivation, and access to resources. Therefore, it's essential to tailor training and support to the needs of each learner to ensure optimal outcomes.

Interferometry is not specifically a medical term, but it is used in certain medical fields such as ophthalmology and optics research. Here is a general definition:

Interferometry is a physical method that uses the interference of waves to measure the differences in phase between two or more waves. In other words, it's a technique that combines two or more light waves to create an interference pattern, which can then be analyzed to extract information about the properties of the light waves, such as their wavelength, amplitude, and phase.

In ophthalmology, interferometry is used in devices like wavefront sensors to measure the aberrations in the eye's optical system. By analyzing the interference pattern created by the light passing through the eye, these devices can provide detailed information about the shape and curvature of the cornea and lens, helping doctors to diagnose and treat various vision disorders.

In optics research, interferometry is used to study the properties of light waves and materials that interact with them. By analyzing the interference patterns created by light passing through different materials or devices, researchers can gain insights into their optical properties, such as their refractive index, thickness, and surface roughness.

Cementoplasty is a medical procedure that involves the injection of bone cement into the damaged or weakened bones to provide stability and pain relief. The cement used in this procedure is typically a type of acrylic material that hardens quickly once it is mixed and introduced into the bone. This procedure is often used to treat spinal compression fractures, vertebroplasty, and kyphoplasty being the most common types of cementoplasty performed on the spine. It can also be used in other parts of the body, such as the pelvis or long bones, to treat tumors, fractures, or joint diseases.

The intraoperative period is the phase of surgical treatment that refers to the time during which the surgery is being performed. It begins when the anesthesia is administered and the patient is prepared for the operation, and it ends when the surgery is completed, the anesthesia is discontinued, and the patient is transferred to the recovery room or intensive care unit (ICU).

During the intraoperative period, the surgical team, including surgeons, anesthesiologists, nurses, and other healthcare professionals, work together to carry out the surgical procedure safely and effectively. The anesthesiologist monitors the patient's vital signs, such as heart rate, blood pressure, oxygen saturation, and body temperature, throughout the surgery to ensure that the patient remains stable and does not experience any complications.

The surgeon performs the operation, using various surgical techniques and instruments to achieve the desired outcome. The surgical team also takes measures to prevent infection, control bleeding, and manage pain during and after the surgery.

Overall, the intraoperative period is a critical phase of surgical treatment that requires close collaboration and communication among members of the healthcare team to ensure the best possible outcomes for the patient.

Medical mass screening, also known as population screening, is a public health service that aims to identify and detect asymptomatic individuals in a given population who have or are at risk of a specific disease. The goal is to provide early treatment, reduce morbidity and mortality, and prevent the spread of diseases within the community.

A mass screening program typically involves offering a simple, quick, and non-invasive test to a large number of people in a defined population, regardless of their risk factors or symptoms. Those who test positive are then referred for further diagnostic tests and appropriate medical interventions. Examples of mass screening programs include mammography for breast cancer detection, PSA (prostate-specific antigen) testing for prostate cancer, and fecal occult blood testing for colorectal cancer.

It is important to note that mass screening programs should be evidence-based, cost-effective, and ethically sound, with clear benefits outweighing potential harms. They should also consider factors such as the prevalence of the disease in the population, the accuracy and reliability of the screening test, and the availability and effectiveness of treatment options.

Osteoma is a benign bone tumor that usually develops on the surface of the bone and is composed of mature lamellar bone. On the other hand, osteoid osteoma is a type of benign bone-forming tumor that is made up of osteoid tissue (immature bone) and is surrounded by a highly vascularized fibrous connective tissue.

Osteoid osteomas are typically smaller than osteomas and can cause significant pain, especially at night, which can be relieved with the use of nonsteroidal anti-inflammatory drugs (NSAIDs). They usually affect young people, particularly males under 30 years old, and commonly involve the long bones of the lower extremities.

While osteomas are generally asymptomatic and do not require treatment unless they cause functional or aesthetic problems, osteoid osteomas may require surgical intervention to alleviate pain and prevent potential complications such as bone deformity or fracture.

Facial asymmetry refers to a condition in which the facial features are not identical or proportionate on both sides of a vertical line drawn down the middle of the face. This can include differences in the size, shape, or positioning of facial features such as the eyes, ears, nose, cheeks, and jaw. Facial asymmetry can be mild and barely noticeable, or it can be more severe and affect a person's appearance and/or functionality of the mouth and jaw.

Facial asymmetry can be present at birth (congenital) or can develop later in life due to various factors such as injury, surgery, growth disorders, nerve damage, or tumors. In some cases, facial asymmetry may not cause any medical problems and may only be of cosmetic concern. However, in other cases, it may indicate an underlying medical condition that requires treatment.

Depending on the severity and cause of the facial asymmetry, treatment options may include cosmetic procedures such as fillers or surgery, orthodontic treatment, physical therapy, or medication to address any underlying conditions.

Electric stimulation therapy, also known as neuromuscular electrical stimulation (NMES) or electromyostimulation, is a therapeutic treatment that uses electrical impulses to stimulate muscles and nerves. The electrical signals are delivered through electrodes placed on the skin near the target muscle group or nerve.

The therapy can be used for various purposes, including:

1. Pain management: Electric stimulation can help reduce pain by stimulating the release of endorphins, which are natural painkillers produced by the body. It can also help block the transmission of pain signals to the brain.
2. Muscle rehabilitation: NMES can be used to prevent muscle atrophy and maintain muscle tone in individuals who are unable to move their muscles due to injury or illness, such as spinal cord injuries or stroke.
3. Improving circulation: Electric stimulation can help improve blood flow and reduce swelling by contracting the muscles and promoting the movement of fluids in the body.
4. Wound healing: NMES can be used to promote wound healing by increasing blood flow, reducing swelling, and improving muscle function around the wound site.
5. Muscle strengthening: Electric stimulation can be used to strengthen muscles by causing them to contract and relax repeatedly, which can help improve muscle strength and endurance.

It is important to note that electric stimulation therapy should only be administered under the guidance of a trained healthcare professional, as improper use can cause harm or discomfort.

Monozygotic twins, also known as identical twins, are derived from a single fertilized egg (ovum) that splits and develops into two separate embryos. This results in the formation of genetically identical individuals who share the same genetic material, with the exception of potential mutations that may occur after the split. Monozygotic twins have the same sex, blood type, and other genetic traits. They are a unique pair of siblings, sharing an extraordinary degree of resemblance in physical characteristics, abilities, and behaviors.

I'm sorry for any confusion, but "Kentucky" is not a medical term or condition. It is a geographical location, being the name of a state in the United States. If you have any questions related to medical conditions or terminology, I would be happy to try and help answer those for you!

'Diseases in Twins' is a field of study that focuses on the similarities and differences in the occurrence, development, and outcomes of diseases among twins. This research can provide valuable insights into the genetic and environmental factors that contribute to various medical conditions.

Twins can be classified into two types: monozygotic (identical) and dizygotic (fraternal). Monozygotic twins share 100% of their genes, while dizygotic twins share about 50%, similar to non-twin siblings. By comparing the concordance rates (the likelihood of both twins having the same disease) between monozygotic and dizygotic twins, researchers can estimate the heritability of a particular disease.

Studying diseases in twins also helps understand the role of environmental factors. When both twins develop the same disease, but they are discordant for certain risk factors (e.g., one twin smokes and the other does not), it suggests that the disease may have a stronger genetic component. On the other hand, when both twins share similar risk factors and develop the disease, it implies that environmental factors play a significant role.

Diseases in Twins research has contributed to our understanding of various medical conditions, including infectious diseases, cancer, mental health disorders, and developmental disorders. This knowledge can lead to better prevention strategies, early detection methods, and more targeted treatments for these diseases.

Animal disease models are specialized animals, typically rodents such as mice or rats, that have been genetically engineered or exposed to certain conditions to develop symptoms and physiological changes similar to those seen in human diseases. These models are used in medical research to study the pathophysiology of diseases, identify potential therapeutic targets, test drug efficacy and safety, and understand disease mechanisms.

The genetic modifications can include knockout or knock-in mutations, transgenic expression of specific genes, or RNA interference techniques. The animals may also be exposed to environmental factors such as chemicals, radiation, or infectious agents to induce the disease state.

Examples of animal disease models include:

1. Mouse models of cancer: Genetically engineered mice that develop various types of tumors, allowing researchers to study cancer initiation, progression, and metastasis.
2. Alzheimer's disease models: Transgenic mice expressing mutant human genes associated with Alzheimer's disease, which exhibit amyloid plaque formation and cognitive decline.
3. Diabetes models: Obese and diabetic mouse strains like the NOD (non-obese diabetic) or db/db mice, used to study the development of type 1 and type 2 diabetes, respectively.
4. Cardiovascular disease models: Atherosclerosis-prone mice, such as ApoE-deficient or LDLR-deficient mice, that develop plaque buildup in their arteries when fed a high-fat diet.
5. Inflammatory bowel disease models: Mice with genetic mutations affecting intestinal barrier function and immune response, such as IL-10 knockout or SAMP1/YitFc mice, which develop colitis.

Animal disease models are essential tools in preclinical research, but it is important to recognize their limitations. Differences between species can affect the translatability of results from animal studies to human patients. Therefore, researchers must carefully consider the choice of model and interpret findings cautiously when applying them to human diseases.

Combined anesthetics refer to the use of two or more types of anesthetic agents together during a medical procedure to produce a desired level of sedation, amnesia, analgesia, and muscle relaxation. This approach can allow for lower doses of individual anesthetic drugs, which may reduce the risk of adverse effects associated with each drug. Common combinations include using a general anesthetic in combination with a regional or local anesthetic technique. The specific choice of combined anesthetics depends on various factors such as the type and duration of the procedure, patient characteristics, and the desired outcomes.

Intestinal pseudo-obstruction, also known as paralytic ileus or functional obstruction, is a gastrointestinal motility disorder characterized by the absence of mechanical obstruction in the intestines, but with symptoms mimicking a mechanical small bowel obstruction. These symptoms may include abdominal distention, cramping, nausea, vomiting, and constipation or difficulty passing stools.

The condition is caused by impaired intestinal motility due to dysfunction of the nerves or muscles that control the movement of food and waste through the digestive system. It can be a chronic or acute condition and may occur as a primary disorder or secondary to other medical conditions, such as surgery, trauma, infections, metabolic disorders, neurological diseases, or certain medications.

Diagnosis of intestinal pseudo-obstruction typically involves imaging studies, such as X-rays or CT scans, to rule out mechanical obstruction and confirm the presence of dilated bowel loops. Manometry and other specialized tests may also be used to assess intestinal motility. Treatment options include medications to stimulate intestinal motility, dietary modifications, and in severe cases, surgery or intravenous nutrition.

A nuclear family, in medical and social sciences, refers to a family structure consisting of two married parents and their biological or adopted children living together in one household. It's the basic unit of a traditional family structure, typically comprising of a father (male parent), a mother (female parent) and their direct offspring. However, it's important to note that there are many different types of families and none is considered universally superior or normative. The concept of a nuclear family has evolved over time and varies across cultures and societies.

Reconstructive surgical procedures are a type of surgery aimed at restoring the form and function of body parts that are defective or damaged due to various reasons such as congenital abnormalities, trauma, infection, tumors, or disease. These procedures can involve the transfer of tissue from one part of the body to another, manipulation of bones, muscles, and tendons, or use of prosthetic materials to reconstruct the affected area. The goal is to improve both the physical appearance and functionality of the body part, thereby enhancing the patient's quality of life. Examples include breast reconstruction after mastectomy, cleft lip and palate repair, and treatment of severe burns.

Clubfoot, also known as talipes equinovarus, is a congenital foot deformity where the foot is twisted inward and downward. The affected foot appears to be turned inward and downward, resembling a club or a bowling pin. This condition usually affects one foot but can occur in both feet as well.

The cause of clubfoot is not fully understood, but it is believed to be a combination of genetic and environmental factors. Clubfoot is often diagnosed at birth or during routine prenatal ultrasound exams. Treatment for clubfoot typically involves nonsurgical methods such as stretching, casting, and bracing to gradually correct the position of the foot over time. In some cases, surgery may be required to release tight tendons and realign the bones in the foot and ankle.

If left untreated, clubfoot can lead to significant mobility issues and difficulty walking or participating in activities. However, with early intervention and consistent treatment, most children with clubfoot are able to lead active and normal lives.

In medical terms, the leg refers to the lower portion of the human body that extends from the knee down to the foot. It includes the thigh (femur), lower leg (tibia and fibula), foot, and ankle. The leg is primarily responsible for supporting the body's weight and enabling movements such as standing, walking, running, and jumping.

The leg contains several important structures, including bones, muscles, tendons, ligaments, blood vessels, nerves, and joints. These structures work together to provide stability, support, and mobility to the lower extremity. Common medical conditions that can affect the leg include fractures, sprains, strains, infections, peripheral artery disease, and neurological disorders.

A dislocation is a condition in which a bone slips out of its normal position in a joint. This can happen as a result of trauma or injury, such as a fall or direct blow to the body. Dislocations can cause pain, swelling, and limited mobility in the affected area. In some cases, a dislocation may also damage surrounding tissues, such as ligaments, tendons, and nerves.

Dislocations are typically treated by reducing the dislocation, which means putting the bone back into its normal position. This is usually done with the help of medication to relieve pain and relaxation techniques to help the person stay still during the reduction. In some cases, surgery may be necessary to repair damaged tissues or if the dislocation cannot be reduced through other methods. After the dislocation has been reduced, the joint may be immobilized with a splint or sling to allow it to heal properly.

It is important to seek medical attention promptly if you suspect that you have a dislocation. If left untreated, a dislocation can lead to further complications, such as joint instability and chronic pain.

'Alloys' is not a medical term. It is a term used in materials science and engineering to describe a mixture or solid solution composed of two or more elements, at least one of which is a metal. The components are typically present in significant amounts (>1% by weight). The properties of alloys, such as their strength, durability, and corrosion resistance, often differ from those of the constituent elements.

While not directly related to medicine, some alloys do have medical applications. For example, certain alloys are used in orthopedic implants, dental restorations, and other medical devices due to their desirable properties such as biocompatibility, strength, and resistance to corrosion.

Physical therapy modalities refer to the various forms of treatment that physical therapists use to help reduce pain, promote healing, and restore function to the body. These modalities can include:

1. Heat therapy: This includes the use of hot packs, paraffin baths, and infrared heat to increase blood flow, relax muscles, and relieve pain.
2. Cold therapy: Also known as cryotherapy, this involves the use of ice packs, cold compresses, or cooling gels to reduce inflammation, numb the area, and relieve pain.
3. Electrical stimulation: This uses electrical currents to stimulate nerves and muscles, which can help to reduce pain, promote healing, and improve muscle strength and function.
4. Ultrasound: This uses high-frequency sound waves to penetrate deep into tissues, increasing blood flow, reducing inflammation, and promoting healing.
5. Manual therapy: This includes techniques such as massage, joint mobilization, and stretching, which are used to improve range of motion, reduce pain, and promote relaxation.
6. Traction: This is a technique that uses gentle pulling on the spine or other joints to help relieve pressure and improve alignment.
7. Light therapy: Also known as phototherapy, this involves the use of low-level lasers or light-emitting diodes (LEDs) to promote healing and reduce pain and inflammation.
8. Therapeutic exercise: This includes a range of exercises that are designed to improve strength, flexibility, balance, and coordination, and help patients recover from injury or illness.

Physical therapy modalities are often used in combination with other treatments, such as manual therapy and therapeutic exercise, to provide a comprehensive approach to rehabilitation and pain management.

An external fixator is a type of orthopedic device used in the treatment of severe fractures or deformities of bones. It consists of an external frame that is attached to the bone with pins or wires that pass through the skin and into the bone. This provides stability to the injured area while allowing for alignment and adjustment of the bone during the healing process.

External fixators are typically used in cases where traditional casting or internal fixation methods are not feasible, such as when there is extensive soft tissue damage, infection, or when a limb needs to be gradually stretched or shortened. They can also be used in reconstructive surgery for bone defects or deformities.

The external frame of the fixator is made up of bars and clamps that are adjustable, allowing for precise positioning and alignment of the bones. The pins or wires that attach to the bone are carefully inserted through small incisions in the skin, and are held in place by the clamps on the frame.

External fixators can be used for a period of several weeks to several months, depending on the severity of the injury and the individual's healing process. During this time, the patient may require regular adjustments and monitoring by an orthopedic surgeon or other medical professional. Once the bone has healed sufficiently, the external fixator can be removed in a follow-up procedure.

Dwarfism is a medical condition that is characterized by short stature, typically with an adult height of 4 feet 10 inches (147 centimeters) or less. It is caused by a variety of genetic and medical conditions that affect bone growth, including skeletal dysplasias, hormonal deficiencies, and chromosomal abnormalities.

Skeletal dysplasias are the most common cause of dwarfism and are characterized by abnormalities in the development and growth of bones and cartilage. Achondroplasia is the most common form of skeletal dysplasia, accounting for about 70% of all cases of dwarfism. It is caused by a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene and results in short limbs, a large head, and a prominent forehead.

Hormonal deficiencies, such as growth hormone deficiency or hypothyroidism, can also cause dwarfism if they are not diagnosed and treated early. Chromosomal abnormalities, such as Turner syndrome (monosomy X) or Down syndrome (trisomy 21), can also result in short stature and other features of dwarfism.

It is important to note that people with dwarfism are not "dwarves" - the term "dwarf" is a medical and sociological term used to describe individuals with this condition, while "dwarves" is a term often used in fantasy literature and media to refer to mythical beings. The use of the term "dwarf" can be considered disrespectful or offensive to some people with dwarfism, so it is important to use respectful language when referring to individuals with this condition.

Immobilization is a medical term that refers to the restriction of normal mobility or motion of a body part, usually to promote healing and prevent further injury. This is often achieved through the use of devices such as casts, splints, braces, slings, or traction. The goal of immobilization is to keep the injured area in a fixed position so that it can heal properly without additional damage. It may be used for various medical conditions, including fractures, dislocations, sprains, strains, and soft tissue injuries. Immobilization helps reduce pain, minimize swelling, and protect the injured site from movement that could worsen the injury or impair healing.

Quality of Life (QOL) is a broad, multidimensional concept that usually includes an individual's physical health, psychological state, level of independence, social relationships, personal beliefs, and their relationship to salient features of their environment. It reflects the impact of disease and treatment on a patient's overall well-being and ability to function in daily life.

The World Health Organization (WHO) defines QOL as "an individual's perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns." It is a subjective concept, meaning it can vary greatly from person to person.

In healthcare, QOL is often used as an outcome measure in clinical trials and other research studies to assess the impact of interventions or treatments on overall patient well-being.

The preoperative period is the time period before a surgical procedure during which various preparations are made to ensure the best possible outcome for the surgery. This includes evaluating the patient's overall health status, identifying and managing any underlying medical conditions that could increase the risk of complications, obtaining informed consent from the patient, and providing preoperative instructions regarding medications, food and drink intake, and other aspects of preparation for the surgery.

The specific activities that occur during the preoperative period may vary depending on the type and complexity of the surgical procedure, as well as the individual needs and medical history of the patient. However, some common elements of the preoperative period include:

* A thorough medical history and physical examination to assess the patient's overall health status and identify any potential risk factors for complications
* Diagnostic tests such as blood tests, imaging studies, or electrocardiograms (ECGs) to provide additional information about the patient's health status
* Consultation with anesthesia providers to determine the appropriate type and dosage of anesthesia for the procedure
* Preoperative teaching to help the patient understand what to expect before, during, and after the surgery
* Management of any underlying medical conditions such as diabetes, heart disease, or lung disease to reduce the risk of complications
* Administration of medications such as antibiotics or anti-coagulants to prevent infection or bleeding
* Fasting instructions to ensure that the stomach is empty during the surgery and reduce the risk of aspiration (inhalation of stomach contents into the lungs)

Overall, the preoperative period is a critical time for ensuring the safety and success of surgical procedures. By taking a thorough and systematic approach to preparing patients for surgery, healthcare providers can help to minimize the risks of complications and ensure the best possible outcomes for their patients.

Lung volume measurements are clinical tests that determine the amount of air inhaled, exhaled, and present in the lungs at different times during the breathing cycle. These measurements include:

1. Tidal Volume (TV): The amount of air inhaled or exhaled during normal breathing, usually around 500 mL in resting adults.
2. Inspiratory Reserve Volume (IRV): The additional air that can be inhaled after a normal inspiration, approximately 3,000 mL in adults.
3. Expiratory Reserve Volume (ERV): The extra air that can be exhaled after a normal expiration, about 1,000-1,200 mL in adults.
4. Residual Volume (RV): The air remaining in the lungs after a maximal exhalation, approximately 1,100-1,500 mL in adults.
5. Total Lung Capacity (TLC): The total amount of air the lungs can hold at full inflation, calculated as TV + IRV + ERV + RV, around 6,000 mL in adults.
6. Functional Residual Capacity (FRC): The volume of air remaining in the lungs after a normal expiration, equal to ERV + RV, about 2,100-2,700 mL in adults.
7. Inspiratory Capacity (IC): The maximum amount of air that can be inhaled after a normal expiration, equal to TV + IRV, around 3,500 mL in adults.
8. Vital Capacity (VC): The total volume of air that can be exhaled after a maximal inspiration, calculated as IC + ERV, approximately 4,200-5,600 mL in adults.

These measurements help assess lung function and identify various respiratory disorders such as chronic obstructive pulmonary disease (COPD), asthma, and restrictive lung diseases.

Intellectual disability (ID) is a term used when there are significant limitations in both intellectual functioning and adaptive behavior, which covers many everyday social and practical skills. This disability originates before the age of 18.

Intellectual functioning, also known as intelligence, refers to general mental capacity, such as learning, reasoning, problem-solving, and other cognitive skills. Adaptive behavior includes skills needed for day-to-day life, such as communication, self-care, social skills, safety judgement, and basic academic skills.

Intellectual disability is characterized by below-average intelligence or mental ability and a lack of skills necessary for day-to-day living. It can be mild, moderate, severe, or profound, depending on the degree of limitation in intellectual functioning and adaptive behavior.

It's important to note that people with intellectual disabilities have unique strengths and limitations, just like everyone else. With appropriate support and education, they can lead fulfilling lives and contribute to their communities in many ways.

Marfan syndrome is a genetic disorder that affects the body's connective tissue. Connective tissue helps to strengthen and support various structures in the body, including the skin, ligaments, blood vessels, and heart. In Marfan syndrome, the body produces an abnormal amount of a protein called fibrillin-1, which is a key component of connective tissue. This leads to problems with the formation and function of connective tissue throughout the body.

The most serious complications of Marfan syndrome typically involve the heart and blood vessels. The aorta, which is the large artery that carries blood away from the heart, can become weakened and stretched, leading to an increased risk of aortic dissection or rupture. Other common features of Marfan syndrome include long, thin fingers and toes; tall stature; a curved spine; and eye problems such as nearsightedness and lens dislocation.

Marfan syndrome is usually inherited in an autosomal dominant pattern, which means that a child has a 50% chance of inheriting the gene mutation from a parent who has the condition. However, about 25% of cases are the result of a new mutation and occur in people with no family history of the disorder. There is no cure for Marfan syndrome, but treatment can help to manage the symptoms and reduce the risk of complications.

"Facies" is a medical term that refers to the typical appearance of a person or part of the body, particularly the face, which may provide clues about their underlying medical condition or genetic background. A specific facies is often associated with certain syndromes or disorders. For example, a "downsyndrome facies" refers to the distinctive facial features commonly found in individuals with Down syndrome, such as a flattened nasal bridge, almond-shaped eyes, and an upward slant to the eyelids.

It's important to note that while facies can provide valuable diagnostic information, it should be used in conjunction with other clinical findings and genetic testing to make a definitive diagnosis. Additionally, facies should be described objectively and without judgment, as they are simply physical characteristics associated with certain medical conditions.

Body image is a person's perception and attitude towards their own physical appearance, shape, and size. It involves how a person thinks and feels about their body, including their self-perceived strengths and flaws. Body image can be influenced by many factors, such as cultural and societal standards of beauty, personal experiences, and media messages. A positive body image is associated with higher self-esteem, confidence, and overall well-being, while a negative body image can contribute to emotional distress, anxiety, depression, and disordered eating behaviors.

Congenital abnormalities, also known as birth defects, are structural or functional anomalies that are present at birth. These abnormalities can develop at any point during fetal development, and they can affect any part of the body. They can be caused by genetic factors, environmental influences, or a combination of both.

Congenital abnormalities can range from mild to severe and may include structural defects such as heart defects, neural tube defects, and cleft lip and palate, as well as functional defects such as intellectual disabilities and sensory impairments. Some congenital abnormalities may be visible at birth, while others may not become apparent until later in life.

In some cases, congenital abnormalities may be detected through prenatal testing, such as ultrasound or amniocentesis. In other cases, they may not be diagnosed until after the baby is born. Treatment for congenital abnormalities varies depending on the type and severity of the defect, and may include surgery, therapy, medication, or a combination of these approaches.

Medical science often defines and describes "walking" as a form of locomotion or mobility where an individual repeatedly lifts and sets down each foot to move forward, usually bearing weight on both legs. It is a complex motor activity that requires the integration and coordination of various systems in the human body, including the musculoskeletal, neurological, and cardiovascular systems.

Walking involves several components such as balance, coordination, strength, and endurance. The ability to walk independently is often used as a measure of functional mobility and overall health status. However, it's important to note that the specific definition of walking may vary depending on the context and the medical or scientific field in question.

Skeletal muscle, also known as striated or voluntary muscle, is a type of muscle that is attached to bones by tendons or aponeuroses and functions to produce movements and support the posture of the body. It is composed of long, multinucleated fibers that are arranged in parallel bundles and are characterized by alternating light and dark bands, giving them a striped appearance under a microscope. Skeletal muscle is under voluntary control, meaning that it is consciously activated through signals from the nervous system. It is responsible for activities such as walking, running, jumping, and lifting objects.

Neck muscles, also known as cervical muscles, are a group of muscles that provide movement, support, and stability to the neck region. They are responsible for various functions such as flexion, extension, rotation, and lateral bending of the head and neck. The main neck muscles include:

1. Sternocleidomastoid: This muscle is located on either side of the neck and is responsible for rotating and flexing the head. It also helps in tilting the head to the same side.

2. Trapezius: This large, flat muscle covers the back of the neck, shoulders, and upper back. It is involved in movements like shrugging the shoulders, rotating and extending the head, and stabilizing the scapula (shoulder blade).

3. Scalenes: These three pairs of muscles are located on the side of the neck and assist in flexing, rotating, and laterally bending the neck. They also help with breathing by elevating the first two ribs during inspiration.

4. Suboccipitals: These four small muscles are located at the base of the skull and are responsible for fine movements of the head, such as tilting and rotating.

5. Longus Colli and Longus Capitis: These muscles are deep neck flexors that help with flexing the head and neck forward.

6. Splenius Capitis and Splenius Cervicis: These muscles are located at the back of the neck and assist in extending, rotating, and laterally bending the head and neck.

7. Levator Scapulae: This muscle is located at the side and back of the neck, connecting the cervical vertebrae to the scapula. It helps with rotation, extension, and elevation of the head and scapula.

Spinal nerve roots are the initial parts of spinal nerves that emerge from the spinal cord through the intervertebral foramen, which are small openings between each vertebra in the spine. These nerve roots carry motor, sensory, and autonomic fibers to and from specific regions of the body. There are 31 pairs of spinal nerve roots in total, with 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal pair. Each root has a dorsal (posterior) and ventral (anterior) ramus that branch off to form the peripheral nervous system. Irritation or compression of these nerve roots can result in pain, numbness, weakness, or loss of reflexes in the affected area.

A neurological examination is a series of tests used to evaluate the functioning of the nervous system, including both the central nervous system (the brain and spinal cord) and peripheral nervous system (the nerves that extend from the brain and spinal cord to the rest of the body). It is typically performed by a healthcare professional such as a neurologist or a primary care physician with specialized training in neurology.

During a neurological examination, the healthcare provider will assess various aspects of neurological function, including:

1. Mental status: This involves evaluating a person's level of consciousness, orientation, memory, and cognitive abilities.
2. Cranial nerves: There are 12 cranial nerves that control functions such as vision, hearing, smell, taste, and movement of the face and neck. The healthcare provider will test each of these nerves to ensure they are functioning properly.
3. Motor function: This involves assessing muscle strength, tone, coordination, and reflexes. The healthcare provider may ask the person to perform certain movements or tasks to evaluate these functions.
4. Sensory function: The healthcare provider will test a person's ability to feel different types of sensations, such as touch, pain, temperature, vibration, and proprioception (the sense of where your body is in space).
5. Coordination and balance: The healthcare provider may assess a person's ability to perform coordinated movements, such as touching their finger to their nose or walking heel-to-toe.
6. Reflexes: The healthcare provider will test various reflexes throughout the body using a reflex hammer.

The results of a neurological examination can help healthcare providers diagnose and monitor conditions that affect the nervous system, such as stroke, multiple sclerosis, Parkinson's disease, or peripheral neuropathy.

Tranexamic acid is an antifibrinolytic medication that is used to reduce or prevent bleeding. It works by inhibiting the activation of plasminogen to plasmin, which is a protease that degrades fibrin clots. By preventing the breakdown of blood clots, tranexamic acid helps to reduce bleeding and promote clot formation.

Tranexamic acid is available in various forms, including tablets, capsules, and injectable solutions. It is used in a variety of clinical settings, such as surgery, trauma, and heavy menstrual bleeding. The medication can be taken orally or administered intravenously, depending on the severity of the bleeding and the patient's medical condition.

Common side effects of tranexamic acid include nausea, vomiting, diarrhea, and headache. Less commonly, the medication may cause allergic reactions, visual disturbances, or seizures. It is important to follow the prescribing physician's instructions carefully when taking tranexamic acid to minimize the risk of side effects and ensure its safe and effective use.

Bone density refers to the amount of bone mineral content (usually measured in grams) in a given volume of bone (usually measured in cubic centimeters). It is often used as an indicator of bone strength and fracture risk. Bone density is typically measured using dual-energy X-ray absorptiometry (DXA) scans, which provide a T-score that compares the patient's bone density to that of a young adult reference population. A T-score of -1 or above is considered normal, while a T-score between -1 and -2.5 indicates osteopenia (low bone mass), and a T-score below -2.5 indicates osteoporosis (porous bones). Regular exercise, adequate calcium and vitamin D intake, and medication (if necessary) can help maintain or improve bone density and prevent fractures.

Medical Definition of Respiration:

Respiration, in physiology, is the process by which an organism takes in oxygen and gives out carbon dioxide. It's also known as breathing. This process is essential for most forms of life because it provides the necessary oxygen for cellular respiration, where the cells convert biochemical energy from nutrients into adenosine triphosphate (ATP), and releases waste products, primarily carbon dioxide.

In humans and other mammals, respiration is a two-stage process:

1. Breathing (or external respiration): This involves the exchange of gases with the environment. Air enters the lungs through the mouth or nose, then passes through the pharynx, larynx, trachea, and bronchi, finally reaching the alveoli where the actual gas exchange occurs. Oxygen from the inhaled air diffuses into the blood, while carbon dioxide, a waste product of metabolism, diffuses from the blood into the alveoli to be exhaled.

2. Cellular respiration (or internal respiration): This is the process by which cells convert glucose and other nutrients into ATP, water, and carbon dioxide in the presence of oxygen. The carbon dioxide produced during this process then diffuses out of the cells and into the bloodstream to be exhaled during breathing.

In summary, respiration is a vital physiological function that enables organisms to obtain the necessary oxygen for cellular metabolism while eliminating waste products like carbon dioxide.

A questionnaire in the medical context is a standardized, systematic, and structured tool used to gather information from individuals regarding their symptoms, medical history, lifestyle, or other health-related factors. It typically consists of a series of written questions that can be either self-administered or administered by an interviewer. Questionnaires are widely used in various areas of healthcare, including clinical research, epidemiological studies, patient care, and health services evaluation to collect data that can inform diagnosis, treatment planning, and population health management. They provide a consistent and organized method for obtaining information from large groups or individual patients, helping to ensure accurate and comprehensive data collection while minimizing bias and variability in the information gathered.

Prevalence, in medical terms, refers to the total number of people in a given population who have a particular disease or condition at a specific point in time, or over a specified period. It is typically expressed as a percentage or a ratio of the number of cases to the size of the population. Prevalence differs from incidence, which measures the number of new cases that develop during a certain period.

A cohort study is a type of observational study in which a group of individuals who share a common characteristic or exposure are followed up over time to determine the incidence of a specific outcome or outcomes. The cohort, or group, is defined based on the exposure status (e.g., exposed vs. unexposed) and then monitored prospectively to assess for the development of new health events or conditions.

Cohort studies can be either prospective or retrospective in design. In a prospective cohort study, participants are enrolled and followed forward in time from the beginning of the study. In contrast, in a retrospective cohort study, researchers identify a cohort that has already been assembled through medical records, insurance claims, or other sources and then look back in time to assess exposure status and health outcomes.

Cohort studies are useful for establishing causality between an exposure and an outcome because they allow researchers to observe the temporal relationship between the two. They can also provide information on the incidence of a disease or condition in different populations, which can be used to inform public health policy and interventions. However, cohort studies can be expensive and time-consuming to conduct, and they may be subject to bias if participants are not representative of the population or if there is loss to follow-up.

Autologous blood transfusion is a medical procedure in which a patient receives their own blood that has been collected and stored prior to surgery or a medical treatment that may cause significant blood loss. The blood is drawn from the patient, typically in the days or weeks leading up to the scheduled procedure, and then stored until it is needed during or after the surgery.

The primary advantage of autologous blood transfusion is that it eliminates the risk of transfusion reactions, infectious disease transmission, and immunomodulation associated with allogeneic (donor) blood transfusions. However, not all patients are candidates for this type of transfusion due to various factors such as medical conditions, low hemoglobin levels, or insufficient time to collect and store the blood before the procedure.

Autologous blood transfusion can be performed using several methods, including preoperative blood donation, acute normovolemic hemodilution, intraoperative cell salvage, and postoperative blood collection. The choice of method depends on various factors, such as the patient's medical condition, the type and extent of surgery, and the availability of resources.

In summary, autologous blood transfusion is a safe and effective way to reduce the need for allogeneic blood transfusions during or after surgical procedures, but it may not be suitable for all patients.

I must clarify that the term "pedigree" is not typically used in medical definitions. Instead, it is often employed in genetics and breeding, where it refers to the recorded ancestry of an individual or a family, tracing the inheritance of specific traits or diseases. In human genetics, a pedigree can help illustrate the pattern of genetic inheritance in families over multiple generations. However, it is not a medical term with a specific clinical definition.

Muscular diseases, also known as myopathies, refer to a group of conditions that affect the functionality and health of muscle tissue. These diseases can be inherited or acquired and may result from inflammation, infection, injury, or degenerative processes. They can cause symptoms such as weakness, stiffness, cramping, spasms, wasting, and loss of muscle function.

Examples of muscular diseases include:

1. Duchenne Muscular Dystrophy (DMD): A genetic disorder that results in progressive muscle weakness and degeneration due to a lack of dystrophin protein.
2. Myasthenia Gravis: An autoimmune disease that causes muscle weakness and fatigue, typically affecting the eyes and face, throat, and limbs.
3. Inclusion Body Myositis (IBM): A progressive muscle disorder characterized by muscle inflammation and wasting, typically affecting older adults.
4. Polymyositis: An inflammatory myopathy that causes muscle weakness and inflammation throughout the body.
5. Metabolic Myopathies: A group of inherited disorders that affect muscle metabolism, leading to exercise intolerance, muscle weakness, and other symptoms.
6. Muscular Dystonias: Involuntary muscle contractions and spasms that can cause abnormal postures or movements.

It is important to note that muscular diseases can have a significant impact on an individual's quality of life, mobility, and overall health. Proper diagnosis and treatment are crucial for managing symptoms and improving outcomes.

Vestibular function tests are a series of diagnostic assessments used to determine the functionality and health of the vestibular system, which is responsible for maintaining balance and spatial orientation. These tests typically include:

1. **Caloric Testing:** This test evaluates the response of each ear to stimulation with warm and cold water or air. The resulting responses are recorded and analyzed to assess the function of the horizontal semicircular canals and the vestibular-ocular reflex (VOR).

2. **Rotary Chair Testing:** This test measures how well the vestibular system adapts to different speeds of rotation. The patient sits in a chair that moves in a controlled, consistent manner while their eye movements are recorded.

3. **Videonystagmography (VNG):** This test uses video goggles to record eye movements in response to various stimuli, such as changes in head position, temperature, and visual environment.

4. **Electronystagmography (ENG):** Similar to VNG, this test records eye movements but uses electrodes placed near the eyes instead of video goggles.

5. **Dix-Hallpike Test:** This is a clinical maneuver used to diagnose benign paroxysmal positional vertigo (BPPV). It involves rapidly moving the patient's head from an upright position to a position where their head is hanging off the end of the examination table.

6. **Head Shaking Test:** This test involves shaking the head back and forth for 15-20 seconds and then observing the patient's eye movements for nystagmus (involuntary eye movement).

These tests help diagnose various vestibular disorders, including benign paroxysmal positional vertigo, labyrinthitis, vestibular neuritis, Meniere's disease, and other balance disorders.

Neural Tube Defects (NTDs) are a group of birth defects that affect the brain, spine, or spinal cord. They occur when the neural tube, which forms the early brain and spinal cord of the embryo, does not close properly during fetal development. This can result in various conditions such as:

1. Anencephaly: a severe defect where most of the brain and skull are missing. Infants with anencephaly are usually stillborn or die shortly after birth.
2. Spina bifida: a condition where the spine does not close properly, leaving a portion of the spinal cord and nerves exposed. This can result in various neurological problems, including paralysis, bladder and bowel dysfunction, and hydrocephalus (fluid buildup in the brain).
3. Encephalocele: a condition where the skull does not close properly, allowing the brain to protrude through an opening in the skull. This can result in various neurological problems, including developmental delays, vision and hearing impairments, and seizures.

NTDs are thought to be caused by a combination of genetic and environmental factors, such as folic acid deficiency, obesity, diabetes, and exposure to certain medications during pregnancy. Folic acid supplementation before and during early pregnancy has been shown to reduce the risk of NTDs.

Nuclear Receptor Subfamily 1, Group F, Member 1 (NR1F1) is a gene that encodes for the retinoic acid-related orphan receptor alpha (RORα) protein. RORα is a type of nuclear receptor, which are transcription factors that regulate gene expression in response to various signals, including hormones and other molecules.

RORα plays important roles in several biological processes, including the regulation of circadian rhythm, immune function, and metabolism. It does this by binding to specific DNA sequences called response elements in the promoter regions of target genes, thereby modulating their transcription.

NR1F1/RORα has been identified as a potential therapeutic target for various diseases, including cancer, inflammatory disorders, and metabolic disorders. However, more research is needed to fully understand its functions and regulatory mechanisms in these contexts.

Spinal cord injuries (SCI) refer to damage to the spinal cord that results in a loss of function, such as mobility or feeling. This injury can be caused by direct trauma to the spine or by indirect damage resulting from disease or degeneration of surrounding bones, tissues, or blood vessels. The location and severity of the injury on the spinal cord will determine which parts of the body are affected and to what extent.

The effects of SCI can range from mild sensory changes to severe paralysis, including loss of motor function, autonomic dysfunction, and possible changes in sensation, strength, and reflexes below the level of injury. These injuries are typically classified as complete or incomplete, depending on whether there is any remaining function below the level of injury.

Immediate medical attention is crucial for spinal cord injuries to prevent further damage and improve the chances of recovery. Treatment usually involves immobilization of the spine, medications to reduce swelling and pressure, surgery to stabilize the spine, and rehabilitation to help regain lost function. Despite advances in treatment, SCI can have a significant impact on a person's quality of life and ability to perform daily activities.

Methyl-CpG-Binding Protein 2 (MeCP2) is a protein that binds to methylated DNA at symmetric CpG sites and plays a crucial role in the regulation of gene expression. MeCP2 is involved in various cellular processes, including chromatin organization, transcriptional repression, and neurological development. Mutations in the MECP2 gene have been associated with several neurodevelopmental disorders, most notably Rett syndrome, a severe X-linked genetic disorder that primarily affects girls. The MeCP2 protein is highly expressed in brain cells, particularly in neurons, where it helps to maintain the balance between methylated and unmethylated DNA, thereby ensuring proper gene expression and neural function.

Intraoperative care refers to the medical care and interventions provided to a patient during a surgical procedure. This care is typically administered by a team of healthcare professionals, including anesthesiologists, surgeons, nurses, and other specialists as needed. The goal of intraoperative care is to maintain the patient's physiological stability throughout the surgery, minimize complications, and ensure the best possible outcome.

Intraoperative care may include:

1. Anesthesia management: Administering and monitoring anesthetic drugs to keep the patient unconscious and free from pain during the surgery.
2. Monitoring vital signs: Continuously tracking the patient's heart rate, blood pressure, oxygen saturation, body temperature, and other key physiological parameters to ensure they remain within normal ranges.
3. Fluid and blood product administration: Maintaining adequate intravascular volume and oxygen-carrying capacity through the infusion of fluids and blood products as needed.
4. Intraoperative imaging: Utilizing real-time imaging techniques, such as X-ray, ultrasound, or CT scans, to guide the surgical procedure and ensure accurate placement of implants or other devices.
5. Neuromonitoring: Using electrophysiological methods to monitor the functional integrity of nerves and neural structures during surgery, particularly in procedures involving the brain, spine, or peripheral nerves.
6. Intraoperative medication management: Administering various medications as needed for pain control, infection prophylaxis, or the treatment of medical conditions that may arise during the surgery.
7. Temperature management: Regulating the patient's body temperature to prevent hypothermia or hyperthermia, which can have adverse effects on surgical outcomes and overall patient health.
8. Communication and coordination: Ensuring effective communication among the members of the surgical team to optimize patient care and safety.

'Infant care' is not a medical term per se, but it generally refers to the provision of nurturing and developmentally appropriate support, supervision, and healthcare for newborns and young children, typically up to 12 months of age. This can include:

1. Meeting basic needs: Providing food (through breastfeeding or formula), changing diapers, ensuring a safe sleep environment, and maintaining hygiene.
2. Monitoring growth and development: Tracking weight gain, height, head circumference, and motor skills to ensure normal developmental progression.
3. Preventive care: Administering vaccinations according to the recommended immunization schedule, performing routine health screenings, and providing guidance on safety practices (e.g., car seat usage, safe sleep).
4. Early detection and management of medical issues: Identifying and addressing common infant health problems such as colic, reflux, or ear infections, and seeking prompt medical attention for more serious conditions.
5. Emotional bonding and attachment: Promoting parent-infant bonding through skin-to-skin contact, responsive feeding, and consistent caregiving.
6. Supporting cognitive and social development: Engaging in age-appropriate play and interaction to foster language development, problem-solving skills, and emotional regulation.
7. Providing education and guidance: Offering evidence-based information on various aspects of infant care, such as feeding, sleep, and soothing techniques, to support parents in their caregiving role.

Evoked potentials, motor, are a category of tests used in clinical neurophysiology to measure the electrical activity generated by the nervous system in response to a stimulus that specifically activates the motor pathways. These tests can help assess the integrity and function of the motor neurons, which are responsible for controlling voluntary muscle movements.

During a motor evoked potentials test, electrodes are placed on the scalp or directly on the surface of the brain or spinal cord. A stimulus is then applied to the motor cortex or peripheral nerves, causing the muscles to contract. The resulting electrical signals are recorded and analyzed to evaluate the conduction velocity, amplitude, and latency of the motor responses.

Motor evoked potentials tests can be useful in diagnosing various neurological conditions, such as multiple sclerosis, spinal cord injuries, and motor neuron diseases. They can also help monitor the progression of these conditions and assess the effectiveness of treatments.

Calcium phosphates are a group of minerals that are important components of bones and teeth. They are also found in some foods and are used in dietary supplements and medical applications. Chemically, calcium phosphates are salts of calcium and phosphoric acid, and they exist in various forms, including hydroxyapatite, which is the primary mineral component of bone tissue. Other forms of calcium phosphates include monocalcium phosphate, dicalcium phosphate, and tricalcium phosphate, which are used as food additives and dietary supplements. Calcium phosphates are important for maintaining strong bones and teeth, and they also play a role in various physiological processes, such as nerve impulse transmission and muscle contraction.

The sternum, also known as the breastbone, is a long, flat bone located in the central part of the chest. It serves as the attachment point for several muscles and tendons, including those involved in breathing. The sternum has three main parts: the manubrium at the top, the body in the middle, and the xiphoid process at the bottom. The upper seven pairs of ribs connect to the sternum via costal cartilages.

Paraplegia is a medical condition characterized by partial or complete loss of motor function and sensation in the lower extremities, typically affecting both legs. This results from damage to the spinal cord, often due to trauma such as accidents, falls, or gunshot wounds, or from diseases like spina bifida, polio, or tumors. The specific area and extent of the injury on the spinal cord determine the severity and location of paralysis. Individuals with paraplegia may require assistive devices for mobility, such as wheelchairs, and may face various health challenges, including pressure sores, urinary tract infections, and chronic pain.

A surgical wound infection, also known as a surgical site infection (SSI), is defined by the Centers for Disease Control and Prevention (CDC) as an infection that occurs within 30 days after surgery (or within one year if an implant is left in place) and involves either:

1. Purulent drainage from the incision;
2. Organisms isolated from an aseptically obtained culture of fluid or tissue from the incision;
3. At least one of the following signs or symptoms of infection: pain or tenderness, localized swelling, redness, or heat; and
4. Diagnosis of surgical site infection by the surgeon or attending physician.

SSIs can be classified as superficial incisional, deep incisional, or organ/space infections, depending on the depth and extent of tissue involvement. They are a common healthcare-associated infection and can lead to increased morbidity, mortality, and healthcare costs.

Bone substitutes are materials that are used to replace missing or damaged bone in the body. They can be made from a variety of materials, including natural bone from other parts of the body or from animals, synthetic materials, or a combination of both. The goal of using bone substitutes is to provide structural support and promote the growth of new bone tissue.

Bone substitutes are often used in dental, orthopedic, and craniofacial surgery to help repair defects caused by trauma, tumors, or congenital abnormalities. They can also be used to augment bone volume in procedures such as spinal fusion or joint replacement.

There are several types of bone substitutes available, including:

1. Autografts: Bone taken from another part of the patient's body, such as the hip or pelvis.
2. Allografts: Bone taken from a deceased donor and processed to remove any cells and infectious materials.
3. Xenografts: Bone from an animal source, typically bovine or porcine, that has been processed to remove any cells and infectious materials.
4. Synthetic bone substitutes: Materials such as calcium phosphate ceramics, bioactive glass, and polymer-based materials that are designed to mimic the properties of natural bone.

The choice of bone substitute material depends on several factors, including the size and location of the defect, the patient's medical history, and the surgeon's preference. It is important to note that while bone substitutes can provide structural support and promote new bone growth, they may not have the same strength or durability as natural bone. Therefore, they may not be suitable for all applications, particularly those that require high load-bearing capacity.

Metabolic bone diseases are a group of conditions that affect the bones and are caused by disorders in the body's metabolism. These disorders can result in changes to the bone structure, density, and strength, leading to an increased risk of fractures and other complications. Some common examples of metabolic bone diseases include:

1. Osteoporosis: a condition characterized by weak and brittle bones that are more likely to break, often as a result of age-related bone loss or hormonal changes.
2. Paget's disease of bone: a chronic disorder that causes abnormal bone growth and deformities, leading to fragile and enlarged bones.
3. Osteomalacia: a condition caused by a lack of vitamin D or problems with the body's ability to absorb it, resulting in weak and soft bones.
4. Hyperparathyroidism: a hormonal disorder that causes too much parathyroid hormone to be produced, leading to bone loss and other complications.
5. Hypoparathyroidism: a hormonal disorder that results in low levels of parathyroid hormone, causing weak and brittle bones.
6. Renal osteodystrophy: a group of bone disorders that occur as a result of chronic kidney disease, including osteomalacia, osteoporosis, and high turnover bone disease.

Treatment for metabolic bone diseases may include medications to improve bone density and strength, dietary changes, exercise, and lifestyle modifications. In some cases, surgery may be necessary to correct bone deformities or fractures.

The cervical vertebrae are the seven vertebrae that make up the upper part of the spine, also known as the neck region. They are labeled C1 to C7, with C1 being closest to the skull and C7 connecting to the thoracic vertebrae in the chest region. The cervical vertebrae have unique structures to allow for a wide range of motion in the neck while also protecting the spinal cord and providing attachment points for muscles and ligaments.

Breathing exercises are a series of deliberate breathing techniques that aim to improve respiratory function, reduce stress and anxiety, and promote relaxation. These exercises can involve various methods such as deep, slow, or rhythmic breathing, often combined with other practices like pursed-lips breathing, diaphragmatic breathing, or alternate nostril breathing. By focusing on the breath and controlling its pace and depth, individuals can experience numerous health benefits, including improved lung capacity, reduced heart rate, increased oxygenation of the blood, and a greater sense of calm and well-being. Breathing exercises are often used as a complementary therapy in various medical and holistic practices, such as yoga, meditation, and stress management programs.

Spinal cord diseases refer to a group of conditions that affect the spinal cord, which is a part of the central nervous system responsible for transmitting messages between the brain and the rest of the body. These diseases can cause damage to the spinal cord, leading to various symptoms such as muscle weakness, numbness, pain, bladder and bowel dysfunction, and difficulty with movement and coordination.

Spinal cord diseases can be congenital or acquired, and they can result from a variety of causes, including infections, injuries, tumors, degenerative conditions, autoimmune disorders, and genetic factors. Some examples of spinal cord diseases include multiple sclerosis, spina bifida, spinal cord injury, herniated discs, spinal stenosis, and motor neuron diseases such as amyotrophic lateral sclerosis (ALS).

The treatment for spinal cord diseases varies depending on the underlying cause and severity of the condition. Treatment options may include medication, physical therapy, surgery, and rehabilitation. In some cases, the damage to the spinal cord may be irreversible, leading to permanent disability or paralysis.

Postoperative hemorrhage is a medical term that refers to bleeding that occurs after a surgical procedure. This condition can range from minor oozing to severe, life-threatening bleeding. Postoperative hemorrhage can occur soon after surgery or even several days later, as the surgical site begins to heal.

The causes of postoperative hemorrhage can vary, but some common factors include:

1. Inadequate hemostasis during surgery: This means that all bleeding was not properly controlled during the procedure, leading to bleeding after surgery.
2. Blood vessel injury: During surgery, blood vessels may be accidentally cut or damaged, causing bleeding after the procedure.
3. Coagulopathy: This is a condition in which the body has difficulty forming blood clots, increasing the risk of postoperative hemorrhage.
4. Use of anticoagulant medications: Medications that prevent blood clots can increase the risk of bleeding after surgery.
5. Infection: An infection at the surgical site can cause inflammation and bleeding.

Symptoms of postoperative hemorrhage may include swelling, pain, warmth, or discoloration around the surgical site, as well as signs of shock such as rapid heartbeat, low blood pressure, and confusion. Treatment for postoperative hemorrhage depends on the severity of the bleeding and may include medications to control bleeding, transfusions of blood products, or additional surgery to stop the bleeding.

Proprioception is the unconscious perception of movement and spatial orientation arising from stimuli within the body itself. It is sometimes described as the "sixth sense" and it's all about knowing where your body parts are, how they are moving, and the effort being used to move them. This information is crucial for motor control, balance, and coordination.

The proprioceptive system includes sensory receptors called proprioreceptors located in muscles, tendons, and joints that send messages to the brain through nerves regarding body position and movement. These messages are then integrated with information from other senses, such as vision and vestibular sense (related to balance), to create a complete understanding of the body's position and motion in space.

Deficits in proprioception can lead to problems with coordination, balance, and fine motor skills.

The Predictive Value of Tests, specifically the Positive Predictive Value (PPV) and Negative Predictive Value (NPV), are measures used in diagnostic tests to determine the probability that a positive or negative test result is correct.

Positive Predictive Value (PPV) is the proportion of patients with a positive test result who actually have the disease. It is calculated as the number of true positives divided by the total number of positive results (true positives + false positives). A higher PPV indicates that a positive test result is more likely to be a true positive, and therefore the disease is more likely to be present.

Negative Predictive Value (NPV) is the proportion of patients with a negative test result who do not have the disease. It is calculated as the number of true negatives divided by the total number of negative results (true negatives + false negatives). A higher NPV indicates that a negative test result is more likely to be a true negative, and therefore the disease is less likely to be present.

The predictive value of tests depends on the prevalence of the disease in the population being tested, as well as the sensitivity and specificity of the test. A test with high sensitivity and specificity will generally have higher predictive values than a test with low sensitivity and specificity. However, even a highly sensitive and specific test can have low predictive values if the prevalence of the disease is low in the population being tested.

Prader-Willi Syndrome (PWS) is a genetic disorder that affects several parts of the body and is characterized by a range of symptoms including:

1. Developmental delays and intellectual disability.
2. Hypotonia (low muscle tone) at birth, which can lead to feeding difficulties in infancy.
3. Excessive appetite and obesity, typically beginning around age 2, due to a persistent hunger drive and decreased satiety.
4. Behavioral problems such as temper tantrums, stubbornness, and compulsive behaviors.
5. Hormonal imbalances leading to short stature, small hands and feet, incomplete sexual development, and decreased bone density.
6. Distinctive facial features including a thin upper lip, almond-shaped eyes, and a narrowed forehead.
7. Sleep disturbances such as sleep apnea or excessive daytime sleepiness.

PWS is caused by the absence of certain genetic material on chromosome 15, which results in abnormal gene function. It affects both males and females equally and has an estimated incidence of 1 in 10,000 to 30,000 live births. Early diagnosis and management can help improve outcomes for individuals with PWS.

Computer-assisted image processing is a medical term that refers to the use of computer systems and specialized software to improve, analyze, and interpret medical images obtained through various imaging techniques such as X-ray, CT (computed tomography), MRI (magnetic resonance imaging), ultrasound, and others.

The process typically involves several steps, including image acquisition, enhancement, segmentation, restoration, and analysis. Image processing algorithms can be used to enhance the quality of medical images by adjusting contrast, brightness, and sharpness, as well as removing noise and artifacts that may interfere with accurate diagnosis. Segmentation techniques can be used to isolate specific regions or structures of interest within an image, allowing for more detailed analysis.

Computer-assisted image processing has numerous applications in medical imaging, including detection and characterization of lesions, tumors, and other abnormalities; assessment of organ function and morphology; and guidance of interventional procedures such as biopsies and surgeries. By automating and standardizing image analysis tasks, computer-assisted image processing can help to improve diagnostic accuracy, efficiency, and consistency, while reducing the potential for human error.

The "age of onset" is a medical term that refers to the age at which an individual first develops or displays symptoms of a particular disease, disorder, or condition. It can be used to describe various medical conditions, including both physical and mental health disorders. The age of onset can have implications for prognosis, treatment approaches, and potential causes of the condition. In some cases, early onset may indicate a more severe or progressive course of the disease, while late-onset symptoms might be associated with different underlying factors or etiologies. It is essential to provide accurate and precise information regarding the age of onset when discussing a patient's medical history and treatment plan.

Genetic predisposition to disease refers to an increased susceptibility or vulnerability to develop a particular illness or condition due to inheriting specific genetic variations or mutations from one's parents. These genetic factors can make it more likely for an individual to develop a certain disease, but it does not guarantee that the person will definitely get the disease. Environmental factors, lifestyle choices, and interactions between genes also play crucial roles in determining if a genetically predisposed person will actually develop the disease. It is essential to understand that having a genetic predisposition only implies a higher risk, not an inevitable outcome.

Pain measurement, in a medical context, refers to the quantification or evaluation of the intensity and/or unpleasantness of a patient's subjective pain experience. This is typically accomplished through the use of standardized self-report measures such as numerical rating scales (NRS), visual analog scales (VAS), or categorical scales (mild, moderate, severe). In some cases, physiological measures like heart rate, blood pressure, and facial expressions may also be used to supplement self-reported pain ratings. The goal of pain measurement is to help healthcare providers better understand the nature and severity of a patient's pain in order to develop an effective treatment plan.

Radiographic image enhancement refers to the process of improving the quality and clarity of radiographic images, such as X-rays, CT scans, or MRI images, through various digital techniques. These techniques may include adjusting contrast, brightness, and sharpness, as well as removing noise and artifacts that can interfere with image interpretation.

The goal of radiographic image enhancement is to provide medical professionals with clearer and more detailed images, which can help in the diagnosis and treatment of medical conditions. This process may be performed using specialized software or hardware tools, and it requires a strong understanding of imaging techniques and the specific needs of medical professionals.

Anatomic models are three-dimensional representations of body structures used for educational, training, or demonstration purposes. They can be made from various materials such as plastic, wax, or rubber and may depict the entire body or specific regions, organs, or systems. These models can be used to provide a visual aid for understanding anatomy, physiology, and pathology, and can be particularly useful in situations where actual human specimens are not available or practical to use. They may also be used for surgical planning and rehearsal, as well as in medical research and product development.

Hemostatics are substances or agents that promote bleeding cessation or prevent the spread of bleeding. They can act in various ways, such as by stimulating the body's natural clotting mechanisms, constricting blood vessels to reduce blood flow, or forming a physical barrier to block the bleeding site.

Hemostatics are often used in medical settings to manage wounds, injuries, and surgical procedures. They can be applied directly to the wound as a powder, paste, or gauze, or they can be administered systemically through intravenous injection. Examples of hemostatic agents include fibrin sealants, collagen-based products, thrombin, and oxidized regenerated cellulose.

It's important to note that while hemostatics can be effective in controlling bleeding, they should be used with caution and only under the guidance of a healthcare professional. Inappropriate use or overuse of hemostatic agents can lead to complications such as excessive clotting, thrombosis, or tissue damage.

A newborn infant is a baby who is within the first 28 days of life. This period is also referred to as the neonatal period. Newborns require specialized care and attention due to their immature bodily systems and increased vulnerability to various health issues. They are closely monitored for signs of well-being, growth, and development during this critical time.

Spinal cord compression is a medical condition that refers to the narrowing of the spinal canal, which puts pressure on the spinal cord and the nerves that branch out from it. This can occur due to various reasons such as degenerative changes in the spine, herniated discs, bone spurs, tumors, or fractures. The compression can lead to a range of symptoms including pain, numbness, tingling, weakness, or loss of bladder and bowel control. In severe cases, it can cause paralysis. Treatment options depend on the underlying cause and may include physical therapy, medication, surgery, or radiation therapy.

Operative time, in medical terms, refers to the duration from when an incision is made in the surgical procedure until the closure of the incision. This period includes any additional time needed for re-exploration or reopening during the same operation. It does not include any time spent performing other procedures that may be necessary but are carried out at a later stage. Operative time is an essential metric used in surgery to assess efficiency, plan resources, and determine costs.

A growth plate, also known as an epiphyseal plate or physis, is a layer of cartilaginous tissue found near the ends of long bones in children and adolescents. This region is responsible for the longitudinal growth of bones during development. The growth plate contains actively dividing cells that differentiate into chondrocytes, which produce and deposit new matrix, leading to bone elongation. Once growth is complete, usually in late adolescence or early adulthood, the growth plates ossify (harden) and are replaced by solid bone, transforming into the epiphyseal line.

Developmental disabilities are a group of conditions that arise in childhood and are characterized by significant impairments in cognitive functioning, physical development, or both. These disabilities can affect various areas of an individual's life, including their ability to learn, communicate, socialize, and take care of themselves.

Examples of developmental disabilities include intellectual disabilities, cerebral palsy, autism spectrum disorder, Down syndrome, and fetal alcohol spectrum disorders. These conditions are typically diagnosed in childhood and can persist throughout an individual's life.

The causes of developmental disabilities are varied and can include genetic factors, environmental influences, and complications during pregnancy or childbirth. In some cases, the exact cause may be unknown.

It is important to note that individuals with developmental disabilities have unique strengths and abilities, as well as challenges. With appropriate support and services, they can lead fulfilling lives and participate actively in their communities.

I'm sorry for any confusion, but "Finite Element Analysis" (FEA) is not a medical term. It is a computational technique used in engineering and physical sciences. FEA is a computerized method for predicting how a product reacts to real-world forces, vibration, heat, fluid flow, and other physical effects. It's a way that engineers can simulate the performance of a product or system before it is built, which can help reduce costs, improve quality, and shorten the development time.

However, in a medical context, FEA might be used in the field of biomechanical engineering to analyze the mechanical behavior of biological systems, such as bones, joints, or soft tissues, under various loads and conditions. This can help researchers and clinicians better understand the mechanisms of injury, disease, or the effects of treatment, and develop more effective prevention, diagnostic, or therapeutic strategies.

Prostheses: Artificial substitutes or replacements for missing body parts, such as limbs, eyes, or teeth. They are designed to restore the function, appearance, or mobility of the lost part. Prosthetic devices can be categorized into several types, including:

1. External prostheses: Devices that are attached to the outside of the body, like artificial arms, legs, hands, and feet. These may be further classified into:
a. Cosmetic or aesthetic prostheses: Primarily designed to improve the appearance of the affected area.
b. Functional prostheses: Designed to help restore the functionality and mobility of the lost limb.
2. Internal prostheses: Implanted artificial parts that replace missing internal organs, bones, or tissues, such as heart valves, hip joints, or intraocular lenses.

Implants: Medical devices or substances that are intentionally placed inside the body to replace or support a missing or damaged biological structure, deliver medication, monitor physiological functions, or enhance bodily functions. Examples of implants include:

1. Orthopedic implants: Devices used to replace or reinforce damaged bones, joints, or cartilage, such as knee or hip replacements.
2. Cardiovascular implants: Devices that help support or regulate heart function, like pacemakers, defibrillators, and artificial heart valves.
3. Dental implants: Artificial tooth roots that are placed into the jawbone to support dental prostheses, such as crowns, bridges, or dentures.
4. Neurological implants: Devices used to stimulate nerves, brain structures, or spinal cord tissues to treat various neurological conditions, like deep brain stimulators for Parkinson's disease or cochlear implants for hearing loss.
5. Ophthalmic implants: Artificial lenses that are placed inside the eye to replace a damaged or removed natural lens, such as intraocular lenses used in cataract surgery.

Nervous system diseases, also known as neurological disorders, refer to a group of conditions that affect the nervous system, which includes the brain, spinal cord, nerves, and muscles. These diseases can affect various functions of the body, such as movement, sensation, cognition, and behavior. They can be caused by genetics, infections, injuries, degeneration, or tumors. Examples of nervous system diseases include Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, migraine, stroke, and neuroinfections like meningitis and encephalitis. The symptoms and severity of these disorders can vary widely, ranging from mild to severe and debilitating.

Turner Syndrome is a genetic disorder that affects females, caused by complete or partial absence of one X chromosome. The typical karyotype is 45,X0 instead of the normal 46,XX in women. This condition leads to distinctive physical features and medical issues in growth, development, and fertility. Characteristic features include short stature, webbed neck, low-set ears, and swelling of the hands and feet. Other potential symptoms can include heart defects, hearing and vision problems, skeletal abnormalities, kidney issues, and learning disabilities. Not all individuals with Turner Syndrome will have every symptom, but most will require medical interventions and monitoring throughout their lives to address various health concerns associated with the condition.

Analysis of Variance (ANOVA) is a statistical technique used to compare the means of two or more groups and determine whether there are any significant differences between them. It is a way to analyze the variance in a dataset to determine whether the variability between groups is greater than the variability within groups, which can indicate that the groups are significantly different from one another.

ANOVA is based on the concept of partitioning the total variance in a dataset into two components: variance due to differences between group means (also known as "between-group variance") and variance due to differences within each group (also known as "within-group variance"). By comparing these two sources of variance, ANOVA can help researchers determine whether any observed differences between groups are statistically significant, or whether they could have occurred by chance.

ANOVA is a widely used technique in many areas of research, including biology, psychology, engineering, and business. It is often used to compare the means of two or more experimental groups, such as a treatment group and a control group, to determine whether the treatment had a significant effect. ANOVA can also be used to compare the means of different populations or subgroups within a population, to identify any differences that may exist between them.

Minimally invasive surgical procedures are a type of surgery that is performed with the assistance of specialized equipment and techniques to minimize trauma to the patient's body. This approach aims to reduce blood loss, pain, and recovery time as compared to traditional open surgeries. The most common minimally invasive surgical procedure is laparoscopy, which involves making small incisions (usually 0.5-1 cm) in the abdomen or chest and inserting a thin tube with a camera (laparoscope) to visualize the internal organs.

The surgeon then uses long, slender instruments inserted through separate incisions to perform the necessary surgical procedures, such as cutting, coagulation, or suturing. Other types of minimally invasive surgical procedures include arthroscopy (for joint surgery), thoracoscopy (for chest surgery), and hysteroscopy (for uterine surgery). The benefits of minimally invasive surgical procedures include reduced postoperative pain, shorter hospital stays, quicker return to normal activities, and improved cosmetic results. However, not all surgeries can be performed using minimally invasive techniques, and the suitability of a particular procedure depends on various factors, including the patient's overall health, the nature and extent of the surgical problem, and the surgeon's expertise.

Locomotion, in a medical context, refers to the ability to move independently and change location. It involves the coordinated movement of the muscles, bones, and nervous system that enables an individual to move from one place to another. This can include walking, running, jumping, or using assistive devices such as wheelchairs or crutches. Locomotion is a fundamental aspect of human mobility and is often assessed in medical evaluations to determine overall health and functioning.

Physiological monitoring is the continuous or intermittent observation and measurement of various body functions or parameters in a patient, with the aim of evaluating their health status, identifying any abnormalities or changes, and guiding clinical decision-making and treatment. This may involve the use of specialized medical equipment, such as cardiac monitors, pulse oximeters, blood pressure monitors, and capnographs, among others. The data collected through physiological monitoring can help healthcare professionals assess the effectiveness of treatments, detect complications early, and make timely adjustments to patient care plans.

The mammary arteries are a set of blood vessels that supply oxygenated blood to the mammary glands, which are the structures in female breasts responsible for milk production during lactation. The largest mammary artery, also known as the internal thoracic or internal mammary artery, originates from the subclavian artery and descends along the inner side of the chest wall. It then branches into several smaller arteries that supply blood to the breast tissue. These include the anterior and posterior intercostal arteries, lateral thoracic artery, and pectoral branches. The mammary arteries are crucial in maintaining the health and function of the breast tissue, and any damage or blockage to these vessels can lead to various breast-related conditions or diseases.

Spinal muscular atrophy (SMA) is a genetic disorder that affects the motor neurons in the spinal cord, leading to muscle weakness and atrophy. It is caused by a mutation in the survival motor neuron 1 (SMN1) gene, which results in a deficiency of SMN protein necessary for the survival of motor neurons.

There are several types of SMA, classified based on the age of onset and severity of symptoms. The most common type is type 1, also known as Werdnig-Hoffmann disease, which presents in infancy and is characterized by severe muscle weakness, hypotonia, and feeding difficulties. Other types include type 2 (intermediate SMA), type 3 (Kugelberg-Welander disease), and type 4 (adult-onset SMA).

The symptoms of SMA may include muscle wasting, fasciculations, weakness, hypotonia, respiratory difficulties, and mobility impairment. The diagnosis of SMA typically involves genetic testing to confirm the presence of a mutation in the SMN1 gene. Treatment options for SMA may include medications, physical therapy, assistive devices, and respiratory support.

Patient selection, in the context of medical treatment or clinical research, refers to the process of identifying and choosing appropriate individuals who are most likely to benefit from a particular medical intervention or who meet specific criteria to participate in a study. This decision is based on various factors such as the patient's diagnosis, stage of disease, overall health status, potential risks, and expected benefits. The goal of patient selection is to ensure that the selected individuals will receive the most effective and safe care possible while also contributing to meaningful research outcomes.

I'm sorry for any confusion, but "pilot projects" is not a medical term per se. Instead, it is a general term used in various fields, including healthcare and medicine, to describe a small-scale initiative that is implemented on a temporary basis to evaluate its feasibility, effectiveness, or impact before deciding whether to expand or continue it.

In the context of healthcare, pilot projects might involve testing new treatment protocols, implementing innovative care models, or introducing technology solutions in a limited setting to assess their potential benefits and drawbacks. The results of these projects can help inform decisions about broader implementation and provide valuable insights for improving the quality and efficiency of healthcare services.

Bone development, also known as ossification, is the process by which bone tissue is formed and grows. This complex process involves several different types of cells, including osteoblasts, which produce new bone matrix, and osteoclasts, which break down and resorb existing bone tissue.

There are two main types of bone development: intramembranous and endochondral ossification. Intramembranous ossification occurs when bone tissue forms directly from connective tissue, while endochondral ossification involves the formation of a cartilage model that is later replaced by bone.

During fetal development, most bones develop through endochondral ossification, starting as a cartilage template that is gradually replaced by bone tissue. However, some bones, such as those in the skull and clavicles, develop through intramembranous ossification.

Bone development continues after birth, with new bone tissue being laid down and existing tissue being remodeled throughout life. This ongoing process helps to maintain the strength and integrity of the skeleton, allowing it to adapt to changing mechanical forces and repair any damage that may occur.

A phenotype is the physical or biochemical expression of an organism's genes, or the observable traits and characteristics resulting from the interaction of its genetic constitution (genotype) with environmental factors. These characteristics can include appearance, development, behavior, and resistance to disease, among others. Phenotypes can vary widely, even among individuals with identical genotypes, due to differences in environmental influences, gene expression, and genetic interactions.

Exercise therapy is a type of medical treatment that uses physical movement and exercise to improve a patient's physical functioning, mobility, and overall health. It is often used as a component of rehabilitation programs for individuals who have experienced injuries, illnesses, or surgeries that have impaired their ability to move and function normally.

Exercise therapy may involve a range of activities, including stretching, strengthening, balance training, aerobic exercise, and functional training. The specific exercises used will depend on the individual's needs, goals, and medical condition.

The benefits of exercise therapy include:

* Improved strength and flexibility
* Increased endurance and stamina
* Enhanced balance and coordination
* Reduced pain and inflammation
* Improved cardiovascular health
* Increased range of motion and joint mobility
* Better overall physical functioning and quality of life.

Exercise therapy is typically prescribed and supervised by a healthcare professional, such as a physical therapist or exercise physiologist, who has experience working with individuals with similar medical conditions. The healthcare professional will create an individualized exercise program based on the patient's needs and goals, and will provide guidance and support to ensure that the exercises are performed safely and effectively.

"Evaluation studies" is a broad term that refers to the systematic assessment or examination of a program, project, policy, intervention, or product. The goal of an evaluation study is to determine its merits, worth, and value by measuring its effects, efficiency, and impact. There are different types of evaluation studies, including formative evaluations (conducted during the development or implementation of a program to provide feedback for improvement), summative evaluations (conducted at the end of a program to determine its overall effectiveness), process evaluations (focusing on how a program is implemented and delivered), outcome evaluations (assessing the short-term and intermediate effects of a program), and impact evaluations (measuring the long-term and broad consequences of a program).

In medical contexts, evaluation studies are often used to assess the safety, efficacy, and cost-effectiveness of new treatments, interventions, or technologies. These studies can help healthcare providers make informed decisions about patient care, guide policymakers in developing evidence-based policies, and promote accountability and transparency in healthcare systems. Examples of evaluation studies in medicine include randomized controlled trials (RCTs) that compare the outcomes of a new treatment to those of a standard or placebo treatment, observational studies that examine the real-world effectiveness and safety of interventions, and economic evaluations that assess the costs and benefits of different healthcare options.

A cross-sectional study is a type of observational research design that examines the relationship between variables at one point in time. It provides a snapshot or a "cross-section" of the population at a particular moment, allowing researchers to estimate the prevalence of a disease or condition and identify potential risk factors or associations.

In a cross-sectional study, data is collected from a sample of participants at a single time point, and the variables of interest are measured simultaneously. This design can be used to investigate the association between exposure and outcome, but it cannot establish causality because it does not follow changes over time.

Cross-sectional studies can be conducted using various data collection methods, such as surveys, interviews, or medical examinations. They are often used in epidemiology to estimate the prevalence of a disease or condition in a population and to identify potential risk factors that may contribute to its development. However, because cross-sectional studies only provide a snapshot of the population at one point in time, they cannot account for changes over time or determine whether exposure preceded the outcome.

Therefore, while cross-sectional studies can be useful for generating hypotheses and identifying potential associations between variables, further research using other study designs, such as cohort or case-control studies, is necessary to establish causality and confirm any findings.

Genetic heterogeneity is a phenomenon in genetics where different genetic variations or mutations in various genes can result in the same or similar phenotypic characteristics, disorders, or diseases. This means that multiple genetic alterations can lead to the same clinical presentation, making it challenging to identify the specific genetic cause based on the observed symptoms alone.

There are two main types of genetic heterogeneity:

1. Allelic heterogeneity: Different mutations in the same gene can cause the same or similar disorders. For example, various mutations in the CFTR gene can lead to cystic fibrosis, a genetic disorder affecting the respiratory and digestive systems.
2. Locus heterogeneity: Mutations in different genes can result in the same or similar disorders. For instance, mutations in several genes, such as BRCA1, BRCA2, and PALB2, are associated with an increased risk of developing breast cancer.

Genetic heterogeneity is essential to consider when diagnosing genetic conditions, evaluating recurrence risks, and providing genetic counseling. It highlights the importance of comprehensive genetic testing and interpretation for accurate diagnosis and appropriate management of genetic disorders.

In the context of medical research, "methods" refers to the specific procedures or techniques used in conducting a study or experiment. This includes details on how data was collected, what measurements were taken, and what statistical analyses were performed. The methods section of a medical paper allows other researchers to replicate the study if they choose to do so. It is considered one of the key components of a well-written research article, as it provides transparency and helps establish the validity of the findings.

Electromyography (EMG) is a medical diagnostic procedure that measures the electrical activity of skeletal muscles during contraction and at rest. It involves inserting a thin needle electrode into the muscle to record the electrical signals generated by the muscle fibers. These signals are then displayed on an oscilloscope and may be heard through a speaker.

EMG can help diagnose various neuromuscular disorders, such as muscle weakness, numbness, or pain, and can distinguish between muscle and nerve disorders. It is often used in conjunction with other diagnostic tests, such as nerve conduction studies, to provide a comprehensive evaluation of the nervous system.

EMG is typically performed by a neurologist or a physiatrist, and the procedure may cause some discomfort or pain, although this is usually minimal. The results of an EMG can help guide treatment decisions and monitor the progression of neuromuscular conditions over time.

Physiological adaptation refers to the changes or modifications that occur in an organism's biological functions or structures as a result of environmental pressures or changes. These adaptations enable the organism to survive and reproduce more successfully in its environment. They can be short-term, such as the constriction of blood vessels in response to cold temperatures, or long-term, such as the evolution of longer limbs in animals that live in open environments.

In the context of human physiology, examples of physiological adaptation include:

1. Acclimatization: The process by which the body adjusts to changes in environmental conditions, such as altitude or temperature. For example, when a person moves to a high-altitude location, their body may produce more red blood cells to compensate for the lower oxygen levels, leading to improved oxygen delivery to tissues.

2. Exercise adaptation: Regular physical activity can lead to various physiological adaptations, such as increased muscle strength and endurance, enhanced cardiovascular function, and improved insulin sensitivity.

3. Hormonal adaptation: The body can adjust hormone levels in response to changes in the environment or internal conditions. For instance, during prolonged fasting, the body releases stress hormones like cortisol and adrenaline to help maintain energy levels and prevent muscle wasting.

4. Sensory adaptation: Our senses can adapt to different stimuli over time. For example, when we enter a dark room after being in bright sunlight, it takes some time for our eyes to adjust to the new light level. This process is known as dark adaptation.

5. Aging-related adaptations: As we age, various physiological changes occur that help us adapt to the changing environment and maintain homeostasis. These include changes in body composition, immune function, and cognitive abilities.

Trifluoperazine is an antipsychotic medication that belongs to the class of drugs called phenothiazines. It works by blocking the action of dopamine, a neurotransmitter in the brain, and helps to reduce symptoms of schizophrenia such as hallucinations, delusions, paranoia, and disordered thought. Trifluoperazine may also be used to manage anxiety or agitation in certain medical conditions. It is available in the form of tablets for oral administration. As with any medication, trifluoperazine should be taken under the supervision of a healthcare provider due to potential side effects and risks associated with its use.

Radiology is a medical specialty that uses imaging technologies to diagnose and treat diseases. These imaging technologies include X-rays, computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, positron emission tomography (PET) scans, ultrasound, and mammography. Radiologists are medical doctors who have completed specialized training in interpreting these images to diagnose medical conditions and guide treatment plans. They also perform image-guided procedures such as biopsies and tumor ablations. The goal of radiology is to provide accurate and timely information to help physicians make informed decisions about patient care.

Aprotinin is a medication that belongs to a class of drugs called serine protease inhibitors. It works by inhibiting the activity of certain enzymes in the body that can cause tissue damage and bleeding. Aprotinin is used in medical procedures such as heart bypass surgery to reduce blood loss and the need for blood transfusions. It is administered intravenously and its use is typically stopped a few days after the surgical procedure.

Aprotinin was first approved for use in the United States in 1993, but its use has been restricted or withdrawn in many countries due to concerns about its safety. In 2006, a study found an increased risk of kidney damage and death associated with the use of aprotinin during heart bypass surgery, leading to its withdrawal from the market in Europe and Canada. However, it is still available for use in the United States under a restricted access program.

It's important to note that the use of aprotinin should be carefully considered and discussed with the healthcare provider, taking into account the potential benefits and risks of the medication.

The supine position is a term used in medicine to describe a body posture where an individual is lying down on their back, with their face and torso facing upwards. This position is often adopted during various medical procedures, examinations, or when resting, as it allows for easy access to the front of the body. It is also the position automatically assumed by most people who are falling asleep.

It's important to note that in the supine position, the head can be flat on the surface or raised with the use of pillows or specialized medical equipment like a hospital bed. This can help to alleviate potential issues such as breathing difficulties or swelling in the face and head.

Recessive genes refer to the alleles (versions of a gene) that will only be expressed when an individual has two copies of that particular allele, one inherited from each parent. If an individual inherits one recessive allele and one dominant allele for a particular gene, the dominant allele will be expressed and the recessive allele will have no effect on the individual's phenotype (observable traits).

Recessive genes can still play a role in determining an individual's genetic makeup and can be passed down through generations even if they are not expressed. If two carriers of a recessive gene have children, there is a 25% chance that their offspring will inherit two copies of the recessive allele and exhibit the associated recessive trait.

Examples of genetic disorders caused by recessive genes include cystic fibrosis, sickle cell anemia, and albinism.

Longitudinal studies are a type of research design where data is collected from the same subjects repeatedly over a period of time, often years or even decades. These studies are used to establish patterns of changes and events over time, and can help researchers identify causal relationships between variables. They are particularly useful in fields such as epidemiology, psychology, and sociology, where the focus is on understanding developmental trends and the long-term effects of various factors on health and behavior.

In medical research, longitudinal studies can be used to track the progression of diseases over time, identify risk factors for certain conditions, and evaluate the effectiveness of treatments or interventions. For example, a longitudinal study might follow a group of individuals over several decades to assess their exposure to certain environmental factors and their subsequent development of chronic diseases such as cancer or heart disease. By comparing data collected at multiple time points, researchers can identify trends and correlations that may not be apparent in shorter-term studies.

Longitudinal studies have several advantages over other research designs, including their ability to establish temporal relationships between variables, track changes over time, and reduce the impact of confounding factors. However, they also have some limitations, such as the potential for attrition (loss of participants over time), which can introduce bias and affect the validity of the results. Additionally, longitudinal studies can be expensive and time-consuming to conduct, requiring significant resources and a long-term commitment from both researchers and study participants.

I apologize, but "video recording" is not a term that has a specific medical definition. It generally refers to the process of capturing and storing moving visual images on electronic media, which is used in various medical fields for different purposes such as surgical training, telemedicine consultations, or monitoring patient conditions. However, there is no unique medical meaning associated with this term.

"Essential genes" refer to a category of genes that are vital for the survival or reproduction of an organism. They encode proteins that are necessary for fundamental biological processes, such as DNA replication, transcription, translation, and cell division. Mutations in essential genes often result in lethality or infertility, making them indispensable for the organism's existence. The identification and study of essential genes can provide valuable insights into the basic mechanisms of life and disease.

I'm sorry for any confusion, but "North America" is not a medical term. It is a geographical term that refers to the third largest continent in the world, which includes countries such as the United States, Canada, and Mexico, among others. If you have any questions related to medical terminology or health topics, I'd be happy to help with those!

Muscle weakness is a condition in which muscles cannot develop the expected level of physical force or power. This results in reduced muscle function and can be caused by various factors, including nerve damage, muscle diseases, or hormonal imbalances. Muscle weakness may manifest as difficulty lifting objects, maintaining posture, or performing daily activities. It is essential to consult a healthcare professional for proper diagnosis and treatment of muscle weakness.

Osteotomy is a surgical procedure in which a bone is cut to shorten, lengthen, or change its alignment. It is often performed to correct deformities or to realign bones that have been damaged by trauma or disease. The bone may be cut straight across (transverse osteotomy) or at an angle (oblique osteotomy). After the bone is cut, it can be realigned and held in place with pins, plates, or screws until it heals. This procedure is commonly performed on bones in the leg, such as the femur or tibia, but can also be done on other bones in the body.

Prosthesis design is a specialized field in medical device technology that involves creating and developing artificial substitutes to replace a missing body part, such as a limb, tooth, eye, or internal organ. The design process typically includes several stages: assessment of the patient's needs, selection of appropriate materials, creation of a prototype, testing and refinement, and final fabrication and fitting of the prosthesis.

The goal of prosthesis design is to create a device that functions as closely as possible to the natural body part it replaces, while also being comfortable, durable, and aesthetically pleasing for the patient. The design process may involve collaboration between medical professionals, engineers, and designers, and may take into account factors such as the patient's age, lifestyle, occupation, and overall health.

Prosthesis design can be highly complex, particularly for advanced devices such as robotic limbs or implantable organs. These devices often require sophisticated sensors, actuators, and control systems to mimic the natural functions of the body part they replace. As a result, prosthesis design is an active area of research and development in the medical field, with ongoing efforts to improve the functionality, comfort, and affordability of these devices for patients.

Dizygotic twins, also known as fraternal twins, are a result of two separate sperm fertilizing two separate eggs during conception. These twins share about 50% of their genes, similar to any non-twin siblings. They may be of the same sex or different sexes and can vary in appearance, personality, and interests. Dizygotic twins typically do not share a placenta or a sac in the womb, but they may share a chorion (outer fetal membrane).

In epidemiology, the incidence of a disease is defined as the number of new cases of that disease within a specific population over a certain period of time. It is typically expressed as a rate, with the number of new cases in the numerator and the size of the population at risk in the denominator. Incidence provides information about the risk of developing a disease during a given time period and can be used to compare disease rates between different populations or to monitor trends in disease occurrence over time.

Reference values, also known as reference ranges or reference intervals, are the set of values that are considered normal or typical for a particular population or group of people. These values are often used in laboratory tests to help interpret test results and determine whether a patient's value falls within the expected range.

The process of establishing reference values typically involves measuring a particular biomarker or parameter in a large, healthy population and then calculating the mean and standard deviation of the measurements. Based on these statistics, a range is established that includes a certain percentage of the population (often 95%) and excludes extreme outliers.

It's important to note that reference values can vary depending on factors such as age, sex, race, and other demographic characteristics. Therefore, it's essential to use reference values that are specific to the relevant population when interpreting laboratory test results. Additionally, reference values may change over time due to advances in measurement technology or changes in the population being studied.

A mutation is a permanent change in the DNA sequence of an organism's genome. Mutations can occur spontaneously or be caused by environmental factors such as exposure to radiation, chemicals, or viruses. They may have various effects on the organism, ranging from benign to harmful, depending on where they occur and whether they alter the function of essential proteins. In some cases, mutations can increase an individual's susceptibility to certain diseases or disorders, while in others, they may confer a survival advantage. Mutations are the driving force behind evolution, as they introduce new genetic variability into populations, which can then be acted upon by natural selection.

Genetic association studies are a type of epidemiological research that aims to identify statistical associations between genetic variations and particular traits or diseases. These studies typically compare the frequency of specific genetic markers, such as single nucleotide polymorphisms (SNPs), in individuals with a given trait or disease to those without it.

The goal of genetic association studies is to identify genetic factors that contribute to the risk of developing common complex diseases, such as diabetes, heart disease, or cancer. By identifying these genetic associations, researchers hope to gain insights into the underlying biological mechanisms of these diseases and develop new strategies for prevention, diagnosis, and treatment.

It's important to note that while genetic association studies can identify statistical associations between genetic markers and traits or diseases, they cannot prove causality. Further research is needed to confirm and validate these findings and to understand the functional consequences of the identified genetic variants.

In medical terms, the face refers to the front part of the head that is distinguished by the presence of the eyes, nose, and mouth. It includes the bones of the skull (frontal bone, maxilla, zygoma, nasal bones, lacrimal bones, palatine bones, inferior nasal conchae, and mandible), muscles, nerves, blood vessels, skin, and other soft tissues. The face plays a crucial role in various functions such as breathing, eating, drinking, speaking, seeing, smelling, and expressing emotions. It also serves as an important identifier for individuals, allowing them to be recognized by others.

Forced Expiratory Volume (FEV) is a medical term used to describe the volume of air that can be forcefully exhaled from the lungs in one second. It is often measured during pulmonary function testing to assess lung function and diagnose conditions such as chronic obstructive pulmonary disease (COPD) or asthma.

FEV is typically expressed as a percentage of the Forced Vital Capacity (FVC), which is the total volume of air that can be exhaled from the lungs after taking a deep breath in. The ratio of FEV to FVC is used to determine whether there is obstruction in the airways, with a lower ratio indicating more severe obstruction.

There are different types of FEV measurements, including FEV1 (the volume of air exhaled in one second), FEV25-75 (the average volume of air exhaled during the middle 50% of the FVC maneuver), and FEV0.5 (the volume of air exhaled in half a second). These measurements can provide additional information about lung function and help guide treatment decisions.

"Sex factors" is a term used in medicine and epidemiology to refer to the differences in disease incidence, prevalence, or response to treatment that are observed between males and females. These differences can be attributed to biological differences such as genetics, hormones, and anatomy, as well as social and cultural factors related to gender.

For example, some conditions such as autoimmune diseases, depression, and osteoporosis are more common in women, while others such as cardiovascular disease and certain types of cancer are more prevalent in men. Additionally, sex differences have been observed in the effectiveness and side effects of various medications and treatments.

It is important to consider sex factors in medical research and clinical practice to ensure that patients receive appropriate and effective care.

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. It is a complex phenomenon that can result from various stimuli, such as thermal, mechanical, or chemical irritation, and it can be acute or chronic. The perception of pain involves the activation of specialized nerve cells called nociceptors, which transmit signals to the brain via the spinal cord. These signals are then processed in different regions of the brain, leading to the conscious experience of pain. It's important to note that pain is a highly individual and subjective experience, and its perception can vary widely among individuals.

Genetic linkage is the phenomenon where two or more genetic loci (locations on a chromosome) tend to be inherited together because they are close to each other on the same chromosome. This occurs during the process of sexual reproduction, where homologous chromosomes pair up and exchange genetic material through a process called crossing over.

The closer two loci are to each other on a chromosome, the lower the probability that they will be separated by a crossover event. As a result, they are more likely to be inherited together and are said to be linked. The degree of linkage between two loci can be measured by their recombination frequency, which is the percentage of meiotic events in which a crossover occurs between them.

Linkage analysis is an important tool in genetic research, as it allows researchers to identify and map genes that are associated with specific traits or diseases. By analyzing patterns of linkage between markers (identifiable DNA sequences) and phenotypes (observable traits), researchers can infer the location of genes that contribute to those traits or diseases on chromosomes.

Medical societies are professional organizations composed of physicians, surgeons, and other healthcare professionals who share a common purpose of promoting medical research, education, and patient care. These societies can focus on specific medical specialties, such as the American Society of Clinical Oncology (ASCO) for cancer specialists or the American College of Surgeons (ACS) for surgeons. They may also address broader issues related to healthcare policy, advocacy, and ethics. Medical societies often provide resources for continuing medical education, publish scientific journals, establish clinical practice guidelines, and offer networking opportunities for members.

In the context of public health and epidemiology, a population refers to a group of individuals who share common characteristics or are defined by specific boundaries and parameters. These parameters can include geographical location, age range, sex, race, ethnicity, exposure to certain risk factors, or shared health status.

The health status and trends of a population are often studied through surveillance and research to understand the determinants of health, disease patterns, and health disparities within the group. This information is then used to inform public health policies, interventions, and programs aimed at improving the overall health and well-being of the population.

Biological models, also known as physiological models or organismal models, are simplified representations of biological systems, processes, or mechanisms that are used to understand and explain the underlying principles and relationships. These models can be theoretical (conceptual or mathematical) or physical (such as anatomical models, cell cultures, or animal models). They are widely used in biomedical research to study various phenomena, including disease pathophysiology, drug action, and therapeutic interventions.

Examples of biological models include:

1. Mathematical models: These use mathematical equations and formulas to describe complex biological systems or processes, such as population dynamics, metabolic pathways, or gene regulation networks. They can help predict the behavior of these systems under different conditions and test hypotheses about their underlying mechanisms.
2. Cell cultures: These are collections of cells grown in a controlled environment, typically in a laboratory dish or flask. They can be used to study cellular processes, such as signal transduction, gene expression, or metabolism, and to test the effects of drugs or other treatments on these processes.
3. Animal models: These are living organisms, usually vertebrates like mice, rats, or non-human primates, that are used to study various aspects of human biology and disease. They can provide valuable insights into the pathophysiology of diseases, the mechanisms of drug action, and the safety and efficacy of new therapies.
4. Anatomical models: These are physical representations of biological structures or systems, such as plastic models of organs or tissues, that can be used for educational purposes or to plan surgical procedures. They can also serve as a basis for developing more sophisticated models, such as computer simulations or 3D-printed replicas.

Overall, biological models play a crucial role in advancing our understanding of biology and medicine, helping to identify new targets for therapeutic intervention, develop novel drugs and treatments, and improve human health.

Congenital heart defects (CHDs) are structural abnormalities in the heart that are present at birth. They can affect any part of the heart's structure, including the walls of the heart, the valves inside the heart, and the major blood vessels that lead to and from the heart.

Congenital heart defects can range from mild to severe and can cause various symptoms depending on the type and severity of the defect. Some common symptoms of CHDs include cyanosis (a bluish tint to the skin, lips, and fingernails), shortness of breath, fatigue, poor feeding, and slow growth in infants and children.

There are many different types of congenital heart defects, including:

1. Septal defects: These are holes in the walls that separate the four chambers of the heart. The two most common septal defects are atrial septal defect (ASD) and ventricular septal defect (VSD).
2. Valve abnormalities: These include narrowed or leaky valves, which can affect blood flow through the heart.
3. Obstruction defects: These occur when blood flow is blocked or restricted due to narrowing or absence of a part of the heart's structure. Examples include pulmonary stenosis and coarctation of the aorta.
4. Cyanotic heart defects: These cause a lack of oxygen in the blood, leading to cyanosis. Examples include tetralogy of Fallot and transposition of the great arteries.

The causes of congenital heart defects are not fully understood, but genetic factors and environmental influences during pregnancy may play a role. Some CHDs can be detected before birth through prenatal testing, while others may not be diagnosed until after birth or later in childhood. Treatment for CHDs may include medication, surgery, or other interventions to improve blood flow and oxygenation of the body's tissues.

Single Nucleotide Polymorphism (SNP) is a type of genetic variation that occurs when a single nucleotide (A, T, C, or G) in the DNA sequence is altered. This alteration must occur in at least 1% of the population to be considered a SNP. These variations can help explain why some people are more susceptible to certain diseases than others and can also influence how an individual responds to certain medications. SNPs can serve as biological markers, helping scientists locate genes that are associated with disease. They can also provide information about an individual's ancestry and ethnic background.

The Chi-square distribution is a continuous probability distribution that is often used in statistical hypothesis testing. It is the distribution of a sum of squares of k independent standard normal random variables. The resulting quantity follows a chi-square distribution with k degrees of freedom, denoted as χ²(k).

The probability density function (pdf) of the Chi-square distribution with k degrees of freedom is given by:

f(x; k) = (1/ (2^(k/2) * Γ(k/2))) \* x^((k/2)-1) \* e^(-x/2), for x > 0 and 0, otherwise.

Where Γ(k/2) is the gamma function evaluated at k/2. The mean and variance of a Chi-square distribution with k degrees of freedom are k and 2k, respectively.

The Chi-square distribution has various applications in statistical inference, including testing goodness-of-fit, homogeneity of variances, and independence in contingency tables.

Medical Definition:

"Risk factors" are any attribute, characteristic or exposure of an individual that increases the likelihood of developing a disease or injury. They can be divided into modifiable and non-modifiable risk factors. Modifiable risk factors are those that can be changed through lifestyle choices or medical treatment, while non-modifiable risk factors are inherent traits such as age, gender, or genetic predisposition. Examples of modifiable risk factors include smoking, alcohol consumption, physical inactivity, and unhealthy diet, while non-modifiable risk factors include age, sex, and family history. It is important to note that having a risk factor does not guarantee that a person will develop the disease, but rather indicates an increased susceptibility.

In the context of medicine and healthcare, "movement" refers to the act or process of changing physical location or position. It involves the contraction and relaxation of muscles, which allows for the joints to move and the body to be in motion. Movement can also refer to the ability of a patient to move a specific body part or limb, which is assessed during physical examinations. Additionally, "movement" can describe the progression or spread of a disease within the body.

Photon Absorptiometry is a medical technique used to measure the absorption of photons (light particles) by tissues or materials. In clinical practice, it is often used as a non-invasive method for measuring bone mineral density (BMD). This technique uses a low-energy X-ray beam or gamma ray to penetrate the tissue and then measures the amount of radiation absorbed by the bone. The amount of absorption is related to the density and thickness of the bone, allowing for an assessment of BMD. It can be used to diagnose osteoporosis and monitor treatment response in patients with bone diseases. There are two types of photon absorptiometry: single-photon absorptiometry (SPA) and dual-photon absorptiometry (DPA). SPA uses one energy level, while DPA uses two different energy levels to measure BMD, providing more precise measurements.

A muscle is a soft tissue in our body that contracts to produce force and motion. It is composed mainly of specialized cells called muscle fibers, which are bound together by connective tissue. There are three types of muscles: skeletal (voluntary), smooth (involuntary), and cardiac. Skeletal muscles attach to bones and help in movement, while smooth muscles are found within the walls of organs and blood vessels, helping with functions like digestion and circulation. Cardiac muscle is the specific type that makes up the heart, allowing it to pump blood throughout the body.

A computer simulation is a process that involves creating a model of a real-world system or phenomenon on a computer and then using that model to run experiments and make predictions about how the system will behave under different conditions. In the medical field, computer simulations are used for a variety of purposes, including:

1. Training and education: Computer simulations can be used to create realistic virtual environments where medical students and professionals can practice their skills and learn new procedures without risk to actual patients. For example, surgeons may use simulation software to practice complex surgical techniques before performing them on real patients.
2. Research and development: Computer simulations can help medical researchers study the behavior of biological systems at a level of detail that would be difficult or impossible to achieve through experimental methods alone. By creating detailed models of cells, tissues, organs, or even entire organisms, researchers can use simulation software to explore how these systems function and how they respond to different stimuli.
3. Drug discovery and development: Computer simulations are an essential tool in modern drug discovery and development. By modeling the behavior of drugs at a molecular level, researchers can predict how they will interact with their targets in the body and identify potential side effects or toxicities. This information can help guide the design of new drugs and reduce the need for expensive and time-consuming clinical trials.
4. Personalized medicine: Computer simulations can be used to create personalized models of individual patients based on their unique genetic, physiological, and environmental characteristics. These models can then be used to predict how a patient will respond to different treatments and identify the most effective therapy for their specific condition.

Overall, computer simulations are a powerful tool in modern medicine, enabling researchers and clinicians to study complex systems and make predictions about how they will behave under a wide range of conditions. By providing insights into the behavior of biological systems at a level of detail that would be difficult or impossible to achieve through experimental methods alone, computer simulations are helping to advance our understanding of human health and disease.

Functional laterality, in a medical context, refers to the preferential use or performance of one side of the body over the other for specific functions. This is often demonstrated in hand dominance, where an individual may be right-handed or left-handed, meaning they primarily use their right or left hand for tasks such as writing, eating, or throwing.

However, functional laterality can also apply to other bodily functions and structures, including the eyes (ocular dominance), ears (auditory dominance), or legs. It's important to note that functional laterality is not a strict binary concept; some individuals may exhibit mixed dominance or no strong preference for one side over the other.

In clinical settings, assessing functional laterality can be useful in diagnosing and treating various neurological conditions, such as stroke or traumatic brain injury, where understanding any resulting lateralized impairments can inform rehabilitation strategies.

Diagnostic errors refer to inaccurate or delayed diagnoses of a patient's medical condition, which can lead to improper or unnecessary treatment and potentially serious harm to the patient. These errors can occur due to various factors such as lack of clinical knowledge, failure to consider all possible diagnoses, inadequate communication between healthcare providers and patients, and problems with testing or interpretation of test results. Diagnostic errors are a significant cause of preventable harm in medical care and have been identified as a priority area for quality improvement efforts.

Peak Expiratory Flow Rate (PEFR) is a measurement of how quickly a person can exhale air from their lungs. It is often used as a quick test to assess breathing difficulties in people with respiratory conditions such as asthma or chronic obstructive pulmonary disease (COPD). PEFR is measured in liters per minute (L/min) and the highest value obtained during a forceful exhalation is recorded as the peak expiratory flow rate. Regular monitoring of PEFR can help to assess the severity of an asthma attack or the effectiveness of treatment.

Neural conduction is the process by which electrical signals, known as action potentials, are transmitted along the axon of a neuron (nerve cell) to transmit information between different parts of the nervous system. This electrical impulse is generated by the movement of ions across the neuronal membrane, and it propagates down the length of the axon until it reaches the synapse, where it can then stimulate the release of neurotransmitters to communicate with other neurons or target cells. The speed of neural conduction can vary depending on factors such as the diameter of the axon, the presence of myelin sheaths (which act as insulation and allow for faster conduction), and the temperature of the environment.

Nonparametric statistics is a branch of statistics that does not rely on assumptions about the distribution of variables in the population from which the sample is drawn. In contrast to parametric methods, nonparametric techniques make fewer assumptions about the data and are therefore more flexible in their application. Nonparametric tests are often used when the data do not meet the assumptions required for parametric tests, such as normality or equal variances.

Nonparametric statistical methods include tests such as the Wilcoxon rank-sum test (also known as the Mann-Whitney U test) for comparing two independent groups, the Wilcoxon signed-rank test for comparing two related groups, and the Kruskal-Wallis test for comparing more than two independent groups. These tests use the ranks of the data rather than the actual values to make comparisons, which allows them to be used with ordinal or continuous data that do not meet the assumptions of parametric tests.

Overall, nonparametric statistics provide a useful set of tools for analyzing data in situations where the assumptions of parametric methods are not met, and can help researchers draw valid conclusions from their data even when the data are not normally distributed or have other characteristics that violate the assumptions of parametric tests.

Intravenous anesthetics are a type of medication that is administered directly into a vein to cause a loss of consciousness and provide analgesia (pain relief) during medical procedures. They work by depressing the central nervous system, inhibiting nerve impulse transmission and ultimately preventing the patient from feeling pain or discomfort during surgery or other invasive procedures.

There are several different types of intravenous anesthetics, each with its own specific properties and uses. Some common examples include propofol, etomidate, ketamine, and barbiturates. These drugs may be used alone or in combination with other medications to provide a safe and effective level of anesthesia for the patient.

The choice of intravenous anesthetic depends on several factors, including the patient's medical history, the type and duration of the procedure, and the desired depth and duration of anesthesia. Anesthesiologists must carefully consider these factors when selecting an appropriate medication regimen for each individual patient.

While intravenous anesthetics are generally safe and effective, they can have side effects and risks, such as respiratory depression, hypotension, and allergic reactions. Anesthesia providers must closely monitor patients during and after the administration of these medications to ensure their safety and well-being.

The term "Asian Continental Ancestry Group" is a medical/ethnic classification used to describe a person's genetic background and ancestry. According to this categorization, individuals with origins in the Asian continent are grouped together. This includes populations from regions such as East Asia (e.g., China, Japan, Korea), South Asia (e.g., India, Pakistan, Bangladesh), Southeast Asia (e.g., Philippines, Indonesia, Thailand), and Central Asia (e.g., Kazakhstan, Uzbekistan, Tajikistan). It is important to note that this broad categorization may not fully capture the genetic diversity within these regions or accurately reflect an individual's specific ancestral origins.

"Bone" is the hard, dense connective tissue that makes up the skeleton of vertebrate animals. It provides support and protection for the body's internal organs, and serves as a attachment site for muscles, tendons, and ligaments. Bone is composed of cells called osteoblasts and osteoclasts, which are responsible for bone formation and resorption, respectively, and an extracellular matrix made up of collagen fibers and mineral crystals.

Bones can be classified into two main types: compact bone and spongy bone. Compact bone is dense and hard, and makes up the outer layer of all bones and the shafts of long bones. Spongy bone is less dense and contains large spaces, and makes up the ends of long bones and the interior of flat and irregular bones.

The human body has 206 bones in total. They can be further classified into five categories based on their shape: long bones, short bones, flat bones, irregular bones, and sesamoid bones.

I am not a medical doctor, but I can provide you with some information on this topic. Self-concept is more commonly discussed in psychology than in medicine, but it still has relevance to understanding individual experiences and behaviors in health and illness.

Self-concept refers to an individual's perception, beliefs, and attitudes about themselves, encompassing various dimensions such as:

1. Physical self (how one perceives their physical appearance, abilities, and health)
2. Social self (how one perceives their relationships with others, social roles, and status)
3. Psychological or personal self (how one perceives their personality traits, values, and beliefs)

Self-concept can influence how people view their own health, cope with illness, and engage in health behaviors. For example, a positive self-concept may contribute to better adherence to treatment plans and healthier lifestyle choices, while negative self-concepts might lead to poorer health outcomes due to decreased motivation or self-efficacy.

Understanding an individual's self-concept can help healthcare professionals tailor their communication style, recommendations, and interventions to better meet the patient's needs and preferences.

Low back pain is a common musculoskeletal disorder characterized by discomfort or pain in the lower part of the back, typically between the costal margin (bottom of the ribcage) and the gluteal folds (buttocks). It can be caused by several factors including strain or sprain of the muscles or ligaments, disc herniation, spinal stenosis, osteoarthritis, or other degenerative conditions affecting the spine. The pain can range from a dull ache to a sharp stabbing sensation and may be accompanied by stiffness, limited mobility, and radiating pain down the legs in some cases. Low back pain is often described as acute (lasting less than 6 weeks), subacute (lasting between 6-12 weeks), or chronic (lasting more than 12 weeks).

Genotype, in genetics, refers to the complete heritable genetic makeup of an individual organism, including all of its genes. It is the set of instructions contained in an organism's DNA for the development and function of that organism. The genotype is the basis for an individual's inherited traits, and it can be contrasted with an individual's phenotype, which refers to the observable physical or biochemical characteristics of an organism that result from the expression of its genes in combination with environmental influences.

It is important to note that an individual's genotype is not necessarily identical to their genetic sequence. Some genes have multiple forms called alleles, and an individual may inherit different alleles for a given gene from each parent. The combination of alleles that an individual inherits for a particular gene is known as their genotype for that gene.

Understanding an individual's genotype can provide important information about their susceptibility to certain diseases, their response to drugs and other treatments, and their risk of passing on inherited genetic disorders to their offspring.

Motor skills are defined as the abilities required to plan, control and execute physical movements. They involve a complex interplay between the brain, nerves, muscles, and the environment. Motor skills can be broadly categorized into two types: fine motor skills, which involve small, precise movements (such as writing or picking up small objects), and gross motor skills, which involve larger movements using the arms, legs, and torso (such as crawling, walking, or running).

Motor skills development is an essential aspect of child growth and development, and it continues to evolve throughout adulthood. Difficulties with motor skills can impact a person's ability to perform daily activities and can be associated with various neurological and musculoskeletal conditions.

Computer-assisted image interpretation is the use of computer algorithms and software to assist healthcare professionals in analyzing and interpreting medical images. These systems use various techniques such as pattern recognition, machine learning, and artificial intelligence to help identify and highlight abnormalities or patterns within imaging data, such as X-rays, CT scans, MRI, and ultrasound images. The goal is to increase the accuracy, consistency, and efficiency of image interpretation, while also reducing the potential for human error. It's important to note that these systems are intended to assist healthcare professionals in their decision making process and not to replace them.

Osteoporosis is a systemic skeletal disease characterized by low bone mass, deterioration of bone tissue, and disruption of bone architecture, leading to increased risk of fractures, particularly in the spine, wrist, and hip. It mainly affects older people, especially postmenopausal women, due to hormonal changes that reduce bone density. Osteoporosis can also be caused by certain medications, medical conditions, or lifestyle factors such as smoking, alcohol abuse, and a lack of calcium and vitamin D in the diet. The diagnosis is often made using bone mineral density testing, and treatment may include medication to slow bone loss, promote bone formation, and prevent fractures.

I'm sorry for any confusion, but "Korea" is not a medical term. It refers to a region in East Asia that is divided into two distinct sovereign states: North Korea (officially the Democratic People's Republic of Korea) and South Korea (officially the Republic of Korea).

If you're looking for medical terms, I'd be happy to help. Could you please provide more context?

Lung diseases refer to a broad category of disorders that affect the lungs and other structures within the respiratory system. These diseases can impair lung function, leading to symptoms such as coughing, shortness of breath, chest pain, and wheezing. They can be categorized into several types based on the underlying cause and nature of the disease process. Some common examples include:

1. Obstructive lung diseases: These are characterized by narrowing or blockage of the airways, making it difficult to breathe out. Examples include chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, and cystic fibrosis.
2. Restrictive lung diseases: These involve stiffening or scarring of the lungs, which reduces their ability to expand and take in air. Examples include idiopathic pulmonary fibrosis, sarcoidosis, and asbestosis.
3. Infectious lung diseases: These are caused by bacteria, viruses, fungi, or parasites that infect the lungs. Examples include pneumonia, tuberculosis, and influenza.
4. Vascular lung diseases: These affect the blood vessels in the lungs, impairing oxygen exchange. Examples include pulmonary embolism, pulmonary hypertension, and chronic thromboembolic pulmonary hypertension (CTEPH).
5. Neoplastic lung diseases: These involve abnormal growth of cells within the lungs, leading to cancer. Examples include small cell lung cancer, non-small cell lung cancer, and mesothelioma.
6. Other lung diseases: These include interstitial lung diseases, pleural effusions, and rare disorders such as pulmonary alveolar proteinosis and lymphangioleiomyomatosis (LAM).

It is important to note that this list is not exhaustive, and there are many other conditions that can affect the lungs. Proper diagnosis and treatment of lung diseases require consultation with a healthcare professional, such as a pulmonologist or respiratory therapist.

Calmodulin is a small, ubiquitous calcium-binding protein that plays a critical role in various intracellular signaling pathways. It functions as a calcium sensor, binding to and regulating the activity of numerous target proteins upon calcium ion (Ca^2+^) binding. Calmodulin is expressed in all eukaryotic cells and participates in many cellular processes, including muscle contraction, neurotransmitter release, gene expression, metabolism, and cell cycle progression.

The protein contains four EF-hand motifs that can bind Ca^2+^ ions. Upon calcium binding, conformational changes occur in the calmodulin structure, exposing hydrophobic surfaces that facilitate its interaction with target proteins. Calmodulin's targets include enzymes (such as protein kinases and phosphatases), ion channels, transporters, and cytoskeletal components. By modulating the activity of these proteins, calmodulin helps regulate essential cellular functions in response to changes in intracellular Ca^2+^ concentrations.

Calmodulin's molecular weight is approximately 17 kDa, and it consists of a single polypeptide chain with 148-150 amino acid residues. The protein can be found in both the cytoplasm and the nucleus of cells. In addition to its role as a calcium sensor, calmodulin has been implicated in various pathological conditions, including cancer, neurodegenerative diseases, and cardiovascular disorders.

Propofol is a short-acting medication that is primarily used for the induction and maintenance of general anesthesia during procedures such as surgery. It belongs to a class of drugs called hypnotics or sedatives, which work by depressing the central nervous system to produce a calming effect. Propofol can also be used for sedation in mechanically ventilated patients in intensive care units and for procedural sedation in various diagnostic and therapeutic procedures outside the operating room.

The medical definition of Propofol is:
A rapid-onset, short-duration intravenous anesthetic agent that produces a hypnotic effect and is used for induction and maintenance of general anesthesia, sedation in mechanically ventilated patients, and procedural sedation. It acts by enhancing the inhibitory effects of gamma-aminobutyric acid (GABA) in the brain, leading to a decrease in neuronal activity and a reduction in consciousness. Propofol has a rapid clearance and distribution, allowing for quick recovery after discontinuation of its administration.

I believe there may be some confusion in your question. "Rabbits" is a common name used to refer to the Lagomorpha species, particularly members of the family Leporidae. They are small mammals known for their long ears, strong legs, and quick reproduction.

However, if you're referring to "rabbits" in a medical context, there is a term called "rabbit syndrome," which is a rare movement disorder characterized by repetitive, involuntary movements of the fingers, resembling those of a rabbit chewing. It is also known as "finger-chewing chorea." This condition is usually associated with certain medications, particularly antipsychotics, and typically resolves when the medication is stopped or adjusted.

Risk assessment in the medical context refers to the process of identifying, evaluating, and prioritizing risks to patients, healthcare workers, or the community related to healthcare delivery. It involves determining the likelihood and potential impact of adverse events or hazards, such as infectious diseases, medication errors, or medical devices failures, and implementing measures to mitigate or manage those risks. The goal of risk assessment is to promote safe and high-quality care by identifying areas for improvement and taking action to minimize harm.

Piperidines are not a medical term per se, but they are a class of organic compounds that have important applications in the pharmaceutical industry. Medically relevant piperidines include various drugs such as some antihistamines, antidepressants, and muscle relaxants.

A piperidine is a heterocyclic amine with a six-membered ring containing five carbon atoms and one nitrogen atom. The structure can be described as a cyclic secondary amine. Piperidines are found in some natural alkaloids, such as those derived from the pepper plant (Piper nigrum), which gives piperidines their name.

In a medical context, it is more common to encounter specific drugs that belong to the class of piperidines rather than the term itself.

Mechanical stress, in the context of physiology and medicine, refers to any type of force that is applied to body tissues or organs, which can cause deformation or displacement of those structures. Mechanical stress can be either external, such as forces exerted on the body during physical activity or trauma, or internal, such as the pressure changes that occur within blood vessels or other hollow organs.

Mechanical stress can have a variety of effects on the body, depending on the type, duration, and magnitude of the force applied. For example, prolonged exposure to mechanical stress can lead to tissue damage, inflammation, and chronic pain. Additionally, abnormal or excessive mechanical stress can contribute to the development of various musculoskeletal disorders, such as tendinitis, osteoarthritis, and herniated discs.

In order to mitigate the negative effects of mechanical stress, the body has a number of adaptive responses that help to distribute forces more evenly across tissues and maintain structural integrity. These responses include changes in muscle tone, joint positioning, and connective tissue stiffness, as well as the remodeling of bone and other tissues over time. However, when these adaptive mechanisms are overwhelmed or impaired, mechanical stress can become a significant factor in the development of various pathological conditions.

Prognosis is a medical term that refers to the prediction of the likely outcome or course of a disease, including the chances of recovery or recurrence, based on the patient's symptoms, medical history, physical examination, and diagnostic tests. It is an important aspect of clinical decision-making and patient communication, as it helps doctors and patients make informed decisions about treatment options, set realistic expectations, and plan for future care.

Prognosis can be expressed in various ways, such as percentages, categories (e.g., good, fair, poor), or survival rates, depending on the nature of the disease and the available evidence. However, it is important to note that prognosis is not an exact science and may vary depending on individual factors, such as age, overall health status, and response to treatment. Therefore, it should be used as a guide rather than a definitive forecast.

Child development is a multidisciplinary field that examines the biological, psychological, emotional, and social growth and changes that occur in human beings between birth and the onset of adulthood. It involves a complex interaction of genetics, environment, culture, and experiences that shape a child's growth and development over time.

Child development is typically divided into several domains, including:

1. Physical Development: This refers to the growth and changes in a child's body, including their motor skills, sensory abilities, and overall health.
2. Cognitive Development: This involves the development of a child's thinking, learning, problem-solving, memory, language, and other mental processes.
3. Emotional Development: This refers to the development of a child's emotional awareness, expression, understanding, and regulation.
4. Social Development: This involves the development of a child's ability to interact with others, form relationships, communicate effectively, and understand social norms and expectations.

Child development is an ongoing process that occurs at different rates and in different ways for each child. Understanding typical patterns of child development can help parents, educators, and healthcare providers support children's growth and identify any potential delays or concerns.

In medical terms, the arm refers to the upper limb of the human body, extending from the shoulder to the wrist. It is composed of three major bones: the humerus in the upper arm, and the radius and ulna in the lower arm. The arm contains several joints, including the shoulder joint, elbow joint, and wrist joint, which allow for a wide range of motion. The arm also contains muscles, blood vessels, nerves, and other soft tissues that are essential for normal function.

Electric stimulation, also known as electrical nerve stimulation or neuromuscular electrical stimulation, is a therapeutic treatment that uses low-voltage electrical currents to stimulate nerves and muscles. It is often used to help manage pain, promote healing, and improve muscle strength and mobility. The electrical impulses can be delivered through electrodes placed on the skin or directly implanted into the body.

In a medical context, electric stimulation may be used for various purposes such as:

1. Pain management: Electric stimulation can help to block pain signals from reaching the brain and promote the release of endorphins, which are natural painkillers produced by the body.
2. Muscle rehabilitation: Electric stimulation can help to strengthen muscles that have become weak due to injury, illness, or surgery. It can also help to prevent muscle atrophy and improve range of motion.
3. Wound healing: Electric stimulation can promote tissue growth and help to speed up the healing process in wounds, ulcers, and other types of injuries.
4. Urinary incontinence: Electric stimulation can be used to strengthen the muscles that control urination and reduce symptoms of urinary incontinence.
5. Migraine prevention: Electric stimulation can be used as a preventive treatment for migraines by applying electrical impulses to specific nerves in the head and neck.

It is important to note that electric stimulation should only be administered under the guidance of a qualified healthcare professional, as improper use can cause harm or discomfort.

Aging is a complex, progressive and inevitable process of bodily changes over time, characterized by the accumulation of cellular damage and degenerative changes that eventually lead to increased vulnerability to disease and death. It involves various biological, genetic, environmental, and lifestyle factors that contribute to the decline in physical and mental functions. The medical field studies aging through the discipline of gerontology, which aims to understand the underlying mechanisms of aging and develop interventions to promote healthy aging and extend the human healthspan.

Demography is the statistical study of populations, particularly in terms of size, distribution, and characteristics such as age, race, gender, and occupation. In medical contexts, demography is often used to analyze health-related data and trends within specific populations. This can include studying the prevalence of certain diseases or conditions, identifying disparities in healthcare access and outcomes, and evaluating the effectiveness of public health interventions. Demographic data can also be used to inform policy decisions and allocate resources to address population health needs.

An exercise test, also known as a stress test or an exercise stress test, is a medical procedure used to evaluate the heart's function and response to physical exertion. It typically involves walking on a treadmill or pedaling a stationary bike while being monitored for changes in heart rate, blood pressure, electrocardiogram (ECG), and sometimes other variables such as oxygen consumption or gas exchange.

During the test, the patient's symptoms, such as chest pain or shortness of breath, are also closely monitored. The exercise test can help diagnose coronary artery disease, assess the severity of heart-related symptoms, and evaluate the effectiveness of treatments for heart conditions. It may also be used to determine a person's safe level of physical activity and fitness.

There are different types of exercise tests, including treadmill stress testing, stationary bike stress testing, nuclear stress testing, and stress echocardiography. The specific type of test used depends on the patient's medical history, symptoms, and overall health status.

Karyotyping is a medical laboratory test used to study the chromosomes in a cell. It involves obtaining a sample of cells from a patient, usually from blood or bone marrow, and then staining the chromosomes so they can be easily seen under a microscope. The chromosomes are then arranged in pairs based on their size, shape, and other features to create a karyotype. This visual representation allows for the identification and analysis of any chromosomal abnormalities, such as extra or missing chromosomes, or structural changes like translocations or inversions. These abnormalities can provide important information about genetic disorders, diseases, and developmental problems.

Logistic models, specifically logistic regression models, are a type of statistical analysis used in medical and epidemiological research to identify the relationship between the risk of a certain health outcome or disease (dependent variable) and one or more independent variables, such as demographic factors, exposure variables, or other clinical measurements.

In contrast to linear regression models, logistic regression models are used when the dependent variable is binary or dichotomous in nature, meaning it can only take on two values, such as "disease present" or "disease absent." The model uses a logistic function to estimate the probability of the outcome based on the independent variables.

Logistic regression models are useful for identifying risk factors and estimating the strength of associations between exposures and health outcomes, adjusting for potential confounders, and predicting the probability of an outcome given certain values of the independent variables. They can also be used to develop clinical prediction rules or scores that can aid in decision-making and patient care.

Muscle contraction is the physiological process in which muscle fibers shorten and generate force, leading to movement or stability of a body part. This process involves the sliding filament theory where thick and thin filaments within the sarcomeres (the functional units of muscles) slide past each other, facilitated by the interaction between myosin heads and actin filaments. The energy required for this action is provided by the hydrolysis of adenosine triphosphate (ATP). Muscle contractions can be voluntary or involuntary, and they play a crucial role in various bodily functions such as locomotion, circulation, respiration, and posture maintenance.

Diagnostic imaging is a medical specialty that uses various technologies to produce visual representations of the internal structures and functioning of the body. These images are used to diagnose injury, disease, or other abnormalities and to monitor the effectiveness of treatment. Common modalities of diagnostic imaging include:

1. Radiography (X-ray): Uses ionizing radiation to produce detailed images of bones, teeth, and some organs.
2. Computed Tomography (CT) Scan: Combines X-ray technology with computer processing to create cross-sectional images of the body.
3. Magnetic Resonance Imaging (MRI): Uses a strong magnetic field and radio waves to generate detailed images of soft tissues, organs, and bones.
4. Ultrasound: Employs high-frequency sound waves to produce real-time images of internal structures, often used for obstetrics and gynecology.
5. Nuclear Medicine: Involves the administration of radioactive tracers to assess organ function or detect abnormalities within the body.
6. Positron Emission Tomography (PET) Scan: Uses a small amount of radioactive material to produce detailed images of metabolic activity in the body, often used for cancer detection and monitoring treatment response.
7. Fluoroscopy: Utilizes continuous X-ray imaging to observe moving structures or processes within the body, such as swallowing studies or angiography.

Diagnostic imaging plays a crucial role in modern medicine, allowing healthcare providers to make informed decisions about patient care and treatment plans.

A biopsy is a medical procedure in which a small sample of tissue is taken from the body to be examined under a microscope for the presence of disease. This can help doctors diagnose and monitor various medical conditions, such as cancer, infections, or autoimmune disorders. The type of biopsy performed will depend on the location and nature of the suspected condition. Some common types of biopsies include:

1. Incisional biopsy: In this procedure, a surgeon removes a piece of tissue from an abnormal area using a scalpel or other surgical instrument. This type of biopsy is often used when the lesion is too large to be removed entirely during the initial biopsy.

2. Excisional biopsy: An excisional biopsy involves removing the entire abnormal area, along with a margin of healthy tissue surrounding it. This technique is typically employed for smaller lesions or when cancer is suspected.

3. Needle biopsy: A needle biopsy uses a thin, hollow needle to extract cells or fluid from the body. There are two main types of needle biopsies: fine-needle aspiration (FNA) and core needle biopsy. FNA extracts loose cells, while a core needle biopsy removes a small piece of tissue.

4. Punch biopsy: In a punch biopsy, a round, sharp tool is used to remove a small cylindrical sample of skin tissue. This type of biopsy is often used for evaluating rashes or other skin abnormalities.

5. Shave biopsy: During a shave biopsy, a thin slice of tissue is removed from the surface of the skin using a sharp razor-like instrument. This technique is typically used for superficial lesions or growths on the skin.

After the biopsy sample has been collected, it is sent to a laboratory where a pathologist will examine the tissue under a microscope and provide a diagnosis based on their findings. The results of the biopsy can help guide further treatment decisions and determine the best course of action for managing the patient's condition.

I'm sorry for any confusion, but "Italy" is not a medical term or concept. It is a country located in Southern Europe. If you have any questions related to medical terminology or health-related topics, I would be happy to try and help answer those for you.

I am not aware of a specific medical definition for the term "China." Generally, it is used to refer to:

1. The People's Republic of China (PRC), which is a country in East Asia. It is the most populous country in the world and the fourth largest by geographical area. Its capital city is Beijing.
2. In a historical context, "China" was used to refer to various dynasties and empires that existed in East Asia over thousands of years. The term "Middle Kingdom" or "Zhongguo" (中国) has been used by the Chinese people to refer to their country for centuries.
3. In a more general sense, "China" can also be used to describe products or goods that originate from or are associated with the People's Republic of China.

If you have a specific context in which you encountered the term "China" related to medicine, please provide it so I can give a more accurate response.

"Chickens" is a common term used to refer to the domesticated bird, Gallus gallus domesticus, which is widely raised for its eggs and meat. However, in medical terms, "chickens" is not a standard term with a specific definition. If you have any specific medical concern or question related to chickens, such as food safety or allergies, please provide more details so I can give a more accurate answer.

Immunologic receptors are specialized proteins found on the surface of immune cells that recognize and bind to specific molecules, known as antigens, on the surface of pathogens or infected cells. This binding triggers a series of intracellular signaling events that activate the immune cell and initiate an immune response.

There are several types of immunologic receptors, including:

1. T-cell receptors (TCRs): These receptors are found on the surface of T cells and recognize antigens presented in the context of major histocompatibility complex (MHC) molecules.
2. B-cell receptors (BCRs): These receptors are found on the surface of B cells and recognize free antigens in solution.
3. Pattern recognition receptors (PRRs): These receptors are found inside immune cells and recognize conserved molecular patterns associated with pathogens, such as lipopolysaccharides and flagellin.
4. Fc receptors: These receptors are found on the surface of various immune cells and bind to the constant region of antibodies, mediating effector functions such as phagocytosis and antibody-dependent cellular cytotoxicity (ADCC).

Immunologic receptors play a critical role in the recognition and elimination of pathogens and infected cells, and dysregulation of these receptors can lead to immune disorders and diseases.

I'm sorry for any confusion, but "Germany" is not a medical term or concept. It is the name of a country in central Europe. If you have any questions related to medical topics, I would be happy to try and help answer those for you!

Sensitivity and specificity are statistical measures used to describe the performance of a diagnostic test or screening tool in identifying true positive and true negative results.

* Sensitivity refers to the proportion of people who have a particular condition (true positives) who are correctly identified by the test. It is also known as the "true positive rate" or "recall." A highly sensitive test will identify most or all of the people with the condition, but may also produce more false positives.
* Specificity refers to the proportion of people who do not have a particular condition (true negatives) who are correctly identified by the test. It is also known as the "true negative rate." A highly specific test will identify most or all of the people without the condition, but may also produce more false negatives.

In medical testing, both sensitivity and specificity are important considerations when evaluating a diagnostic test. High sensitivity is desirable for screening tests that aim to identify as many cases of a condition as possible, while high specificity is desirable for confirmatory tests that aim to rule out the condition in people who do not have it.

It's worth noting that sensitivity and specificity are often influenced by factors such as the prevalence of the condition in the population being tested, the threshold used to define a positive result, and the reliability and validity of the test itself. Therefore, it's important to consider these factors when interpreting the results of a diagnostic test.

Exercise tolerance is a term used to describe the ability of an individual to perform physical activity or exercise without experiencing symptoms such as shortness of breath, chest pain, or undue fatigue. It is often used as a measure of cardiovascular fitness and can be assessed through various tests, such as a stress test or a six-minute walk test. Exercise intolerance may indicate the presence of underlying medical conditions, such as heart disease, lung disease, or deconditioning.

Evidence-Based Medicine (EBM) is a medical approach that combines the best available scientific evidence with clinical expertise and patient values to make informed decisions about diagnosis, treatment, and prevention of diseases. It emphasizes the use of systematic research, including randomized controlled trials and meta-analyses, to guide clinical decision making. EBM aims to provide the most effective and efficient care while minimizing variations in practice, reducing errors, and improving patient outcomes.

Combined modality therapy (CMT) is a medical treatment approach that utilizes more than one method or type of therapy simultaneously or in close succession, with the goal of enhancing the overall effectiveness of the treatment. In the context of cancer care, CMT often refers to the combination of two or more primary treatment modalities, such as surgery, radiation therapy, and systemic therapies (chemotherapy, immunotherapy, targeted therapy, etc.).

The rationale behind using combined modality therapy is that each treatment method can target cancer cells in different ways, potentially increasing the likelihood of eliminating all cancer cells and reducing the risk of recurrence. The specific combination and sequence of treatments will depend on various factors, including the type and stage of cancer, patient's overall health, and individual preferences.

For example, a common CMT approach for locally advanced rectal cancer may involve preoperative (neoadjuvant) chemoradiation therapy, followed by surgery to remove the tumor, and then postoperative (adjuvant) chemotherapy. This combined approach allows for the reduction of the tumor size before surgery, increases the likelihood of complete tumor removal, and targets any remaining microscopic cancer cells with systemic chemotherapy.

It is essential to consult with a multidisciplinary team of healthcare professionals to determine the most appropriate CMT plan for each individual patient, considering both the potential benefits and risks associated with each treatment method.

Comorbidity is the presence of one or more additional health conditions or diseases alongside a primary illness or condition. These co-occurring health issues can have an impact on the treatment plan, prognosis, and overall healthcare management of an individual. Comorbidities often interact with each other and the primary condition, leading to more complex clinical situations and increased healthcare needs. It is essential for healthcare professionals to consider and address comorbidities to provide comprehensive care and improve patient outcomes.

Cost-benefit analysis (CBA) is a systematic process used to compare the costs and benefits of different options to determine which one provides the greatest net benefit. In a medical context, CBA can be used to evaluate the value of medical interventions, treatments, or policies by estimating and monetizing all the relevant costs and benefits associated with each option.

The costs included in a CBA may include direct costs such as the cost of the intervention or treatment itself, as well as indirect costs such as lost productivity or time away from work. Benefits may include improved health outcomes, reduced morbidity or mortality, and increased quality of life.

Once all the relevant costs and benefits have been identified and quantified, they are typically expressed in monetary terms to allow for a direct comparison. The option with the highest net benefit (i.e., the difference between total benefits and total costs) is considered the most cost-effective.

It's important to note that CBA has some limitations and can be subject to various biases and assumptions, so it should be used in conjunction with other evaluation methods to ensure a comprehensive understanding of the value of medical interventions or policies.

A chronic disease is a long-term medical condition that often progresses slowly over a period of years and requires ongoing management and care. These diseases are typically not fully curable, but symptoms can be managed to improve quality of life. Common chronic diseases include heart disease, stroke, cancer, diabetes, arthritis, and COPD (chronic obstructive pulmonary disease). They are often associated with advanced age, although they can also affect children and younger adults. Chronic diseases can have significant impacts on individuals' physical, emotional, and social well-being, as well as on healthcare systems and society at large.

Body weight is the measure of the force exerted on a scale or balance by an object's mass, most commonly expressed in units such as pounds (lb) or kilograms (kg). In the context of medical definitions, body weight typically refers to an individual's total weight, which includes their skeletal muscle, fat, organs, and bodily fluids.

Healthcare professionals often use body weight as a basic indicator of overall health status, as it can provide insights into various aspects of a person's health, such as nutritional status, metabolic function, and risk factors for certain diseases. For example, being significantly underweight or overweight can increase the risk of developing conditions like malnutrition, diabetes, heart disease, and certain types of cancer.

It is important to note that body weight alone may not provide a complete picture of an individual's health, as it does not account for factors such as muscle mass, bone density, or body composition. Therefore, healthcare professionals often use additional measures, such as body mass index (BMI), waist circumference, and blood tests, to assess overall health status more comprehensively.

I'm sorry for any confusion, but "Linear Models" is actually a term from the field of statistics and machine learning, rather than medicine. A linear model is a type of statistical model that is used to analyze the relationship between two or more variables. In a linear model, the relationship between the dependent variable (the outcome or result) and the independent variable(s) (the factors being studied) is assumed to be linear, meaning that it can be described by a straight line on a graph.

The equation for a simple linear model with one independent variable (x) and one dependent variable (y) looks like this:

y = β0 + β1*x + ε

In this equation, β0 is the y-intercept or the value of y when x equals zero, β1 is the slope or the change in y for each unit increase in x, and ε is the error term or the difference between the actual values of y and the predicted values of y based on the linear model.

Linear models are widely used in medical research to study the relationship between various factors (such as exposure to a risk factor or treatment) and health outcomes (such as disease incidence or mortality). They can also be used to adjust for confounding variables, which are factors that may influence both the independent variable and the dependent variable, and thus affect the observed relationship between them.

Chromosome mapping, also known as physical mapping, is the process of determining the location and order of specific genes or genetic markers on a chromosome. This is typically done by using various laboratory techniques to identify landmarks along the chromosome, such as restriction enzyme cutting sites or patterns of DNA sequence repeats. The resulting map provides important information about the organization and structure of the genome, and can be used for a variety of purposes, including identifying the location of genes associated with genetic diseases, studying evolutionary relationships between organisms, and developing genetic markers for use in breeding or forensic applications.

Activities of Daily Living (ADL) are routine self-care activities that individuals usually do every day without assistance. These activities are widely used as a measure to determine the functional status and independence of a person, particularly in the elderly or those with disabilities or chronic illnesses. The basic ADLs include:

1. Personal hygiene: Bathing, washing hands and face, brushing teeth, grooming, and using the toilet.
2. Dressing: Selecting appropriate clothes and dressing oneself.
3. Eating: Preparing and consuming food, either independently or with assistive devices.
4. Mobility: Moving in and out of bed, chairs, or wheelchairs, walking independently or using mobility aids.
5. Transferring: Moving from one place to another, such as getting in and out of a car, bath, or bed.

There are also more complex Instrumental Activities of Daily Living (IADLs) that assess an individual's ability to manage their own life and live independently. These include managing finances, shopping for groceries, using the telephone, taking medications as prescribed, preparing meals, and housekeeping tasks.

"Swine" is a common term used to refer to even-toed ungulates of the family Suidae, including domestic pigs and wild boars. However, in a medical context, "swine" often appears in the phrase "swine flu," which is a strain of influenza virus that typically infects pigs but can also cause illness in humans. The 2009 H1N1 pandemic was caused by a new strain of swine-origin influenza A virus, which was commonly referred to as "swine flu." It's important to note that this virus is not transmitted through eating cooked pork products; it spreads from person to person, mainly through respiratory droplets produced when an infected person coughs or sneezes.

Regression analysis is a statistical technique used in medicine, as well as in other fields, to examine the relationship between one or more independent variables (predictors) and a dependent variable (outcome). It allows for the estimation of the average change in the outcome variable associated with a one-unit change in an independent variable, while controlling for the effects of other independent variables. This technique is often used to identify risk factors for diseases or to evaluate the effectiveness of medical interventions. In medical research, regression analysis can be used to adjust for potential confounding variables and to quantify the relationship between exposures and health outcomes. It can also be used in predictive modeling to estimate the probability of a particular outcome based on multiple predictors.

A feasibility study is a preliminary investigation or analysis conducted to determine the viability of a proposed project, program, or product. In the medical field, feasibility studies are often conducted before implementing new treatments, procedures, equipment, or facilities. These studies help to assess the practicality and effectiveness of the proposed intervention, as well as its potential benefits and risks.

Feasibility studies in healthcare typically involve several steps:

1. Problem identification: Clearly define the problem that the proposed project, program, or product aims to address.
2. Objectives setting: Establish specific, measurable, achievable, relevant, and time-bound (SMART) objectives for the study.
3. Literature review: Conduct a thorough review of existing research and best practices related to the proposed intervention.
4. Methodology development: Design a methodology for data collection and analysis that will help answer the research questions and achieve the study's objectives.
5. Resource assessment: Evaluate the availability and adequacy of resources, including personnel, time, and finances, required to carry out the proposed intervention.
6. Risk assessment: Identify potential risks and challenges associated with the implementation of the proposed intervention and develop strategies to mitigate them.
7. Cost-benefit analysis: Estimate the costs and benefits of the proposed intervention, including direct and indirect costs, as well as short-term and long-term benefits.
8. Stakeholder engagement: Engage relevant stakeholders, such as patients, healthcare providers, administrators, and policymakers, to gather their input and support for the proposed intervention.
9. Decision-making: Based on the findings of the feasibility study, make an informed decision about whether or not to proceed with the proposed project, program, or product.

Feasibility studies are essential in healthcare as they help ensure that resources are allocated efficiently and effectively, and that interventions are evidence-based, safe, and beneficial for patients.

Oxygen is a colorless, odorless, tasteless gas that constitutes about 21% of the earth's atmosphere. It is a crucial element for human and most living organisms as it is vital for respiration. Inhaled oxygen enters the lungs and binds to hemoglobin in red blood cells, which carries it to tissues throughout the body where it is used to convert nutrients into energy and carbon dioxide, a waste product that is exhaled.

Medically, supplemental oxygen therapy may be provided to patients with conditions such as chronic obstructive pulmonary disease (COPD), pneumonia, heart failure, or other medical conditions that impair the body's ability to extract sufficient oxygen from the air. Oxygen can be administered through various devices, including nasal cannulas, face masks, and ventilators.

A research design in medical or healthcare research is a systematic plan that guides the execution and reporting of research to address a specific research question or objective. It outlines the overall strategy for collecting, analyzing, and interpreting data to draw valid conclusions. The design includes details about the type of study (e.g., experimental, observational), sampling methods, data collection techniques, data analysis approaches, and any potential sources of bias or confounding that need to be controlled for. A well-defined research design helps ensure that the results are reliable, generalizable, and relevant to the research question, ultimately contributing to evidence-based practice in medicine and healthcare.

Body Mass Index (BMI) is a measure used to assess whether a person has a healthy weight for their height. It's calculated by dividing a person's weight in kilograms by the square of their height in meters. Here is the medical definition:

Body Mass Index (BMI) = weight(kg) / [height(m)]^2

According to the World Health Organization, BMI categories are defined as follows:

* Less than 18.5: Underweight
* 18.5-24.9: Normal or healthy weight
* 25.0-29.9: Overweight
* 30.0 and above: Obese

It is important to note that while BMI can be a useful tool for identifying weight issues in populations, it does have limitations when applied to individuals. For example, it may not accurately reflect body fat distribution or muscle mass, which can affect health risks associated with excess weight. Therefore, BMI should be used as one of several factors when evaluating an individual's health status and risk for chronic diseases.

Scoliosis is a medical condition characterized by an abnormal lateral curvature of the spine, which most often occurs in the thoracic or lumbar regions. The curvature can be "C" or "S" shaped and may also include rotation of the vertebrae. Mild scoliosis doesn't typically cause problems, but severe cases can interfere with breathing and other bodily functions.

The exact cause of most scoliosis is unknown, but it may be related to genetic factors. It often develops in the pre-teen or teenage years, particularly in girls, and is more commonly found in individuals with certain neuromuscular disorders such as cerebral palsy and muscular dystrophy.

Treatment for scoliosis depends on the severity of the curve, its location, and the age and expected growth of the individual. Mild cases may only require regular monitoring to ensure the curve doesn't worsen. More severe cases may require bracing or surgery to correct the curvature and prevent it from getting worse.

"Motor activity" is a general term used in the field of medicine and neuroscience to refer to any kind of physical movement or action that is generated by the body's motor system. The motor system includes the brain, spinal cord, nerves, and muscles that work together to produce movements such as walking, talking, reaching for an object, or even subtle actions like moving your eyes.

Motor activity can be voluntary, meaning it is initiated intentionally by the individual, or involuntary, meaning it is triggered automatically by the nervous system without conscious control. Examples of voluntary motor activity include deliberately lifting your arm or kicking a ball, while examples of involuntary motor activity include heartbeat, digestion, and reflex actions like jerking your hand away from a hot stove.

Abnormalities in motor activity can be a sign of neurological or muscular disorders, such as Parkinson's disease, cerebral palsy, or multiple sclerosis. Assessment of motor activity is often used in the diagnosis and treatment of these conditions.

... Research Society. (2014). Congenital Scoliosis. Scoliosis Research Society. "Congenital Scoliosis - Scoliosis ... Scoliosis associated with known syndromes is often sub-classified as "syndromic scoliosis". Scoliosis can be associated with ... Wikimedia Commons has media related to Scoliosis. Scoliosis at Curlie Early Onset Scoliosis is the abnormal, side-to-side curve ... Another form of secondary scoliosis is degenerative scoliosis, also known as de novo scoliosis, which develops later in life ...
"Adolescent Idiopathic Scoliosis". Scoliosis Research Society. Retrieved 2022-05-21. "Idiopathic Scoliosis in Children and ... "Scoliosis and breathing". Scoliosis Association. Retrieved 2022-09-30. Qiabi M, Chagnon K, Beaupré A, Hercun J, Rakovich G ( ... Adolescent idiopathic scoliosis is a rather common disorder in which the spine starts abnormally curving sideways (scoliosis) ... "Schroth Method for Scoliosis". www.hopkinsmedicine.org. 2021-08-08. Retrieved 2022-09-30. "Adolescent Idiopathic Scoliosis: ...
The Scoliosis Research Society website serves as an educational resource to patients, and a professional resource for health ... The Scoliosis Research Society (SRS) is a non-profit, professional, international organization made up of physicians and allied ... Scoliosis Research Society website (All articles with dead external links, Articles with dead external links from May 2018, ... A prospective, controlled study based on data from the Brace Study of the Scoliosis Research Society, J Bone Joint Surg Am 77: ...
The management of scoliosis is complex and is determined primarily by the type of scoliosis encountered: syndromic, congenital ... Indications for Scoliosis Bracing: Scoliosis professionals determine the proper bracing method for a patient after a complete ... Scoliosis (1.2 ed.). SeattleChildren.org: American Journal of Surgery. 2012. pp. 115-116. Scoliosis Surgery. News-medical.net. ... 5-8. "Idiopathic Scoliosis". Scoliosis Research Society (SRS). Archived from the original on 2014-01-16. Retrieved 2014-01-02. ...
... : About Scoliosis and Spinal Disorders (accessed 3 March 2016) NCBI Journals: Scoliosis and ... Published by BioMed Central, Scoliosis and Spinal Disorders is the official journal of the Society on Scoliosis Orthopaedic and ... "Scoliosis". In 2016, the journal changed its name to Scoliosis and Spinal Disorders, and extended its scope to include all ... Scoliosis and Spinal Disorders (ISSN 2397-1789) is an international, multidisciplinary open-access, peer-reviewed, online-only ...
Idiopathic scoliosis can appear at different ages. Infantile idiopathic scoliosis that appear from the birth to 3 years old, ... Juvenile idiopathic scoliosis that appear from the 4 to 10 years old, account for 10.5% of idiopathic scoliosis. Adolescent ... Scoliosis in swimmers; Becker, TJ, 1986. Why do idiopathic scoliosis patients participate more in gymnastics?; C. Meyer, E. ... The idiopathic scoliosis accounts for 80-90% of scoliosis cases. Its pathogenesis is unknown. However, changes in the ...
... is a very rare genetic disorder which is characterized by ocular/ ... "OMIM Entry - 610319 - RHIZOMELIC DYSPLASIA, SCOLIOSIS, AND RETINITIS PIGMENTOSA". www.omim.org. Retrieved 2022-06-13. "OMIM ... ". "Rhizomelic dysplasia, scoliosis, and retinitis pigmentosa , Genetic and Rare Diseases Information Center (GARD) - an NCATS ... Wide ribs Photophobia Deltoid tuberosity prominence Reduced visual acuity Limb rhizomelia Cone-rod dystrophy Scoliosis ...
... and idiopathic scoliosis". Scoliosis. 1: 21. doi:10.1186/1748-7161-1-21. PMC 1769398. PMID 17176459. Jenkins RN, Osborne- ... have been linked to idiopathic scoliosis. GRCh38: Ensembl release 89: ENSG00000162510 - Ensembl, May 2017 GRCm38: Ensembl ...
"Scoliosis". The Lecturio Medical Concept Library. Retrieved 27 August 2021. https://www.nlm.nih.gov/medlineplus/bonediseases. ... Osteoporosis Porotic hyperostosis Primary hyperparathyroidism Renal osteodystrophy Salter-Harris fracture Scoliosis Water on ...
Scoliosis is identified in more than half of these patients. In most of the symptomatic patients, the spinal cord is split into ... scoliosis; and incontinence. In adulthood, the signs and symptoms often include progressive sensory and motor problems and loss ...
"Editorial Board". Scoliosis. 2015. Retrieved 24 July 2015. "Officers of the Society". The International Research Society of ... Dangerfield is associate editor of the journal Scoliosis. He is a past secretary and honorary member of The International ...
... scoliosis; cervical hyperlordosis; thoracic hyperkyphosis; lumbar hyperlordosis; narrowing of the space available for the ...
... scoliosis). Adams Forward Bend Test "National Scoliosis Foundation". Archived from the original on 2014-11-21. Retrieved 2014- ... "Evaluation of the iPhone with an acrylic sleeve versus the Scoliometer for rib hump measurement in scoliosis". Scoliosis. 7 (14 ...
... is distinguished from scoliosis, a condition in which the spine has a sideways curve. While most cases of kyphosis are ... "Scoliosis and Spinal Curvatures". Medtronic. Nowak JE (5 December 2019). Kishner S (ed.). "Scheuermann Disease". Medscape. ... Weiss HR, Goodall D (August 2008). "Rate of complications in scoliosis surgery - a systematic review of the Pub Med literature ... Lehnert-Schroth, Christa (2007). Three-Dimensional Treatment for Scoliosis: A Physiotherapeutic Method for Deformities of the ...
2 Reduced upper segment/lower segment ratio AND increased arm/height AND no severe scoliosis = 1 Scoliosis or thoracolumbar ... "Scoliosis". The Lecturio Medical Concept Library. Archived from the original on 10 August 2021. Retrieved 10 August 2021. " ... Retinal detachment Scoliosis Sleep apnea Stretch marks not from pregnancy or obesity Teeth crowded "Narrow, thin face" ... people with Marfan syndrome may have abnormal lateral curvature of the spine scoliosis, thoracic lordosis, abnormal indentation ...
Weiss HR, Goodall D (August 2008). "Rate of complications in scoliosis surgery - a systematic review of the Pub Med literature ... Lehnert-Schroth C (2007). Three-Dimensional Treatment for Scoliosis: A Physiotherapeutic Method for Deformities of the Spine. ... Scoliosis. 4 (1): 22. doi:10.1186/1748-7161-4-22. PMC 2761858. PMID 19788753. Horn SR, Poorman GW, Tishelman JC, Bortz CA, ... Spinal fusion for kyphosis and scoliosis is an extremely invasive surgery. The risk of complications is estimated to be about ...
Although the cause of scoliosis can sometimes remain unknown (idiopathic scoliosis) there is treatment available that targets ... Symptoms of scoliosis in mild cases usually exhibit abnormal posture, back pain, tingling or numbness in the legs and in worse ... Scoliosis, is a medical condition where a person's spine has several irregular curves that are located between the neck and the ... "Scoliosis". Harvard Health Publishing. April 2019. Retrieved 16 July 2020. "atraumatic". {{cite journal}}: Cite journal ...
... in human biology and adolescent idiopathic scoliosis". Scoliosis. 2: 6. doi:10.1186/1748-7161-2-6. ISSN 1748-7161. PMC 1855314 ...
Scoliosis: Ascending the Curve. New York: M. Evans and Company, Inc., 1999. Scoliosis. Boca Raton, FL: Scoliosis Association, ... Scoliosis is a three-dimensional curvature of the spine. Spinal fusion is when the discs of the spine are removed and replaced ... Minimally invasive thoracic spinal fusion is one of the newest[when?] approaches to scoliosis surgery. Instead of a vertical ...
Scoliosis. Medline Plus. https://medlineplus.gov/scoliosis.html A New Scoliosis Treatment: Vertebral Body Tethering. https:// ... www.shrinershospitalsforchildren.org/philadelphia/scoliosis-and-spine-care1 VBT Procedure Corrects Scoliosis, Helps Wrestler ... Left untreated, severe scoliosis can worsen and eventually affect a person's lungs and heart. In the 1950s and 1960s, doctors ... Anterior vertebral body tethering (AVBT) is a relatively new surgery for the treatment of scoliosis in pediatric patients. ...
There is very weak evidence for chiropractic care for adult scoliosis (curved or rotated spine) and no scientific data for ... Everett CR, Patel RK (September 2007). "A systematic literature review of nonsurgical treatment in adult scoliosis". Spine. 32 ... Romano M, Negrini S (2008). "Manual therapy as a conservative treatment for adolescent idiopathic scoliosis: a systematic ... review". Scoliosis. 3: 2. doi:10.1186/1748-7161-3-2. PMC 2262872. PMID 18211702. Hawk C, Khorsan R, Lisi AJ, Ferrance RJ, Evans ...
Scoliosis is a common spinal disease in which the spine has a curvature usually in the shape of the letter "C" or "S". This is ... Generally, if the hips or shoulders are uneven, or if the spine curves, it is due to scoliosis and should be seen by a doctor. ... "Scoliosis". New York Times. Ishimoto, Y.; Yoshimura, N.; Muraki, S.; Yamada, H.; Nagata, K.; Hashizume, H.; Takiguchi, N.; ... scoliosis, or even unusual sensations in the legs. The primary tumor has no known cause, although there are possible answers ...
In 1992, Charles d'Amato and Barry McCoy created a board on which scoliosis patients can be positioned in a way that corrected ... The Providence brace is among the treatments prescribed to slow or stop further curvature of the spine as scoliosis patients ... Fayssoux, Reginald S.; Cho, Robert H.; Herman, Martin J. (March 2010). "A History of Bracing for Idiopathic Scoliosis in North ... The Providence brace is a nighttime spinal orthosis for the treatment of adolescent idiopathic scoliosis (AIS). The brace is ...
There is no scientific data that supports the use of spinal manipulation for idiopathic adolescent scoliosis. Spinal ... Romano M, Negrini S (2008). "Manual therapy as a conservative treatment for adolescent idiopathic scoliosis: a systematic ... "A systematic literature review of nonsurgical treatment in adult scoliosis". Spine. 32 (19 Suppl): S130-4. doi:10.1097/BRS. ... review". Scoliosis. 3 (1): 2. doi:10.1186/1748-7161-3-2. PMC 2262872. PMID 18211702. Michaleff ZA, Lin CW, Maher CG, van Tulder ...
Surgery, at some point, might be an option for scoliosis. Scoliosis, which is a sideways curve of the persons vertebrate, is ... "Scoliosis: MedlinePlus". www.nlm.nih.gov. Retrieved 2016-05-12. "OMIM Entry - # 254090 - Ullrich Congenital Muscular Dystrophy ...
ISBN 978-1-4511-7660-5. Herring, John A. (2020). "9. Scoliosis". Tachdjian's Pediatric Orthopaedics: From the Texas Scottish ...
Brissaud's scoliosis - a form of scoliosis giving "a list of the lumbar part of the spine away from the affected side in ... "Brissaud's scoliosis". Who Named It?. Retrieved 13 January 2007. Enersen, Ole Daniel. "Brissaud-Sicard syndrome". Who Named It ...
She is also a founder of the Straight UP! Scoliosis charity. Currently, she works as a Regional Developer for Hay Group. At ... In 2012, she was diagnosed with scoliosis. Her condition triggered her to advocate people on prevention and treatment of the ... After being diagnosed with scoliosis in 2012, Frimpong became a health activist and advocate on prevention and treatment of the ...
Idiopathic scoliosis The prognosis, diagnosis, and operative indications related to curve patterns and the age at onset, ... His clinical and research interests were in the surgery of the hand and the surgical treatment of scoliosis. James became ... British Volume 36-B, Issue 101 Feb 1954, 36-49 The management of infants with scoliosis. Journal of Bone and Joint Surgery. 57B ... James, J. I. P. (1954). "Idiopathic scoliosis". The Journal of Bone and Joint Surgery. British Volume. 36-B (1): 36-49. doi: ...
Sarwark is active in the Scoliosis Research Society and has served on its education committee, chaired the Fellowship C, co- ... He is recognized leader in the evaluation, management, and research of scoliosis in children. Sarwark is active in numerous ... ". "Scoliosis Research Society". "Home". www.aoassn.org. "AACPDM - American Academy for Cerebral Palsy and Developmental ...
Scoliosis Research Society. (2014). Congenital Scoliosis. Scoliosis Research Society. "Congenital Scoliosis - Scoliosis ... Scoliosis associated with known syndromes is often sub-classified as "syndromic scoliosis". Scoliosis can be associated with ... Wikimedia Commons has media related to Scoliosis. Scoliosis at Curlie Early Onset Scoliosis is the abnormal, side-to-side curve ... Another form of secondary scoliosis is degenerative scoliosis, also known as de novo scoliosis, which develops later in life ...
Scoliosis causes a sideways curve of your backbone, or spine. It is most common in late childhood and early teens. Find out ... Scoliosis causes a sideways curve of your backbone, or spine. These curves are often S- or C-shaped. Scoliosis is most common ... Scoliosis in Children and Teens (National Institute of Arthritis and Musculoskeletal and Skin Diseases) Also in Spanish ... People with mild scoliosis might only need checkups to see if the curve is getting worse. Others might need to wear a brace or ...
Health care providers treat scoliosis with back braces or surgery when needed. ... Scoliosis makes a persons spine curve from side to side. Large curves can cause health problems like pain or breathing trouble ... scoliosis. Its usually found when people begin going through puberty.. What Causes Idiopathic Scoliosis?. Idiopathic scoliosis ... Some states have school-based scoliosis screening programs.. How Is Scoliosis Diagnosed?. If you think you have scoliosis, make ...
Health care providers treat scoliosis with back braces or surgery when needed. ... Scoliosis makes a persons spine curve from side to side. Large curves can cause health problems like pain or breathing trouble ... Idiopathic scoliosis. This is the most common type of scoliosis. Kids can get it at any age, but most of the time it happens ... What Is Scoliosis?. Scoliosis is when the vertebrae (the small bones in the spine) form a curved line instead of being straight ...
The REFLECT Scoliosis Correction System is a non-fusion spinal device intended to treat idiopathic scoliosis in children and ... The REFLECT Scoliosis Correction System is a non-fusion spinal device intended to treat idiopathic scoliosis, an abnormal curve ... The REFLECT™ Scoliosis Correction System includes bone screws, staples, a cord, and locking caps. Staples and bone screws are ... The REFLECT Scoliosis Correction System is indicated for people whose bones have not stopped growing (skeletally immature) and ...
Idiopathic scoliosis is the most common type of spinal deformity confronting orthopedic surgeons. Its onset can be rather ... Idiopathic scoliosis in twins studied by DNA fingerprinting: the incidence and type of scoliosis. J Bone Joint Surg Br. 1998 ... Idiopathic scoliosis. Lonstein JE, Bradford DS, Winter RB, Ogilvie J, eds. Moes Textbook of Scoliosis and Other Spinal ... 15] is recognized as the first physician to treat scoliosis with a brace. He also recognized that once a patient with scoliosis ...
... scoliosis ). Explore symptoms, inheritance, genetics of this condition. ... Horizontal gaze palsy with progressive scoliosis (HGPPS) is a disorder that affects vision and also causes an abnormal ... Familial idiopathic scoliosis associated with congenital encephalopathy. *Familial infantile scoliosis associated with ... The cause of progressive scoliosis in HGPPS is unclear. Researchers are working to determine why the effects of ROBO3 mutations ...
Minimally invasive surgery, Spine procedure, Scoliosis, Kyphosis, Early-onset scoliosis, Spinal tumor, Juvenile scolios...is ... Cervical scoliosis surgery, Halo skull traction, Skeletal traction, Cervical laminectomy, Lumbar scoliosis surgery, ... Cervical scoliosis surgery, Lumbar spinal fusion (Deprecated), Cervical laminectomy, Lumbar scoliosis surgery, Thoracic ... Cervical scoliosis surgery, Lumbar laminectomy, Cervical diskectomy, Thoracic scoliosis surgery, Thoracic laminectomy, Thoracic ...
Information from Medtronic on the benefits and risks of scoliosis surgery. ... Surgery is an option used primarily for severe scoliosis (curves greater than 45 degrees) or for curves that do not respond to ... Additional complications that may be associated with scoliosis surgery include loss of proper spinal balance, failure, of the ... and other important medical information that pertains to scoliosis surgery. ...
He suffers from a severe form of Scoliosis, a progressive spinal deformity that requires immediate surgery, and Marfan Syndrome ...
Scoliosis is a condition of side-to-side spinal curves that measure greater than 10 degrees. Learn more about types, causes, ... What is scoliosis?. Scoliosis is a common condition that affects many children and adolescents. Simply defined, scoliosis is a ... What is Scoliosis?. Scoliosis is a condition of side-to-side spinal curves that measure greater than 10º. On an x-ray, the ... Idiopathic scoliosis is by far the most common kind of scoliosis. Idiopathic means that the cause is not known, and it ...
But people with scoliosis have a spine that curves ... Scoliosis is an abnormal curving of the spine. Your spine is ... Other types of scoliosis are:. *Congenital scoliosis: This type of scoliosis is present at birth. It occurs when the babys ... Routine scoliosis screening is now done in middle schools. Such screening has helped detect early scoliosis in many children. ... Most of the time, the cause of scoliosis is unknown. This is called idiopathic scoliosis. It is the most common type. It is ...
The Scoliosis Research Society (SRS) Annual Meeting is a forum for the realization of the Societys mission and goals, the ... This curriculum-based, interactive regional course is designed for 125-150 delegates by the Scoliosis Research Society and ...
Description: The revolutionary Peak Scoliosis Bracing System is an unloader brace specifically designed to relieve the pain ... Description: The revolutionary Peak Scoliosis Bracing System is an unloader brace specifically designed to relieve the pain ... associated with adult scoliosis. This patented, highly adjustable brace from Aspen has been shown to significantly relieve pain ... associated with adult scoliosis. This patented, highly adjustable brace from Aspen has been shown to significantly relieve pain ...
Although most youths with scoliosis will not develop clinical symptoms, scoliosis can progress to rib deformity and respiratory ... The incidence of scoliosis is about the same in males and females; however, females have up to a 10-fold greater risk of curve ... For decades, scoliosis screenings were a routine part of school physical examinations in adolescents. The U.S. Preventive ... In contrast, the Scoliosis Research Society, American Academy of Orthopaedic Surgeons, American Academy of Pediatrics, and ...
Hello ladies does anyone have experience with getting an epidural with a spinal scoliosis. I have read the epidural may not be ... Didnt realize I had scoliosis till I was giving birth to my first born in 2013, my scoliosis isnt that bad though either. ... I have scoliosis and had a spinal block and like PP it was terrible. She could not get the needle in and attempted numerous ... I have read the epidural may not be effective if you have a scoliosis? . I am very worried about pain management due to this. ...
Scoliosis is the side to side curvature of the spine. Every spine has a natural front to back curve. A side to side curve may ... What is Scoliosis?. Scoliosis is the side to side curvature of the spine. Every spine has a natural front to back curve. A side ... What is the cause of scoliosis?. 80% of scoliosis cases do not have a cause or they are "idiopathic". ... For more information on the treatment of scoliosis in children or to make an appointment call 314.454.5437 or Email Us. ...
Resource Guide for Scoliosis. by Cynthia M. Johnson, MA. Ortho Info-American Academy of Orthopaedic Surgeons. 9400 West Higgins ... This site has educational material with graphics, pictures, and x-rays to show how scoliosis affects the spine. Information on ... This website offers detailed information about scoliosis, arthritis and rheumatic diseases, and skin and muscle disorders. Also ...
Scoliosis is a sideways curvature of the spine . It can affect people of any age, but most often starts in children aged 10 to ... A Carrickfergus schoolgirl who was facing a wait of at least a year for spinal surgery to treat her scoliosis may be able to ... They say that if they exceed their target, theyve promised to pay it forward to help other children who have scoliosis. ...
This book follows a context-based approach to management of early-onset scoliosis (EOS) in countries with limited resources in ... Early Onset Scoliosis Guidelines for Management in Resource-Limited Settings Edited By Alaaeldin (Alaa) Azmi Ahmad, Aakash ... This book follows a context-based approach to management of early-onset scoliosis (EOS) in countries with limited resources in ... First book to focus on countries with limited resources for the management of early onset scoliosis. ...
Hi, my name is Andrew, and Im fundraising… Andrew Woods needs your support for Jazmyns Scoliosis (VBT) Surgery ... Not only was she born with congenital scoliosis, she was also born with bilateral cleft feet. She has had a total of seven ... She was born with congenital scoliosis, and her surgery is fast approaching. The high costs for Jazmyns surgery are ... I have included some links for more information on Scoliosis, VBT, Cleft Feet and Shriners Childrens Hospital. ...
Topics discussed include the history and classification of scoliosis; the connection between idiopathic scoliosis, orthodontics ... new physical therapy interventions for scoliosis; effects of load carriage on children with scoliosis; and the relationship of ... Scoliosis is a lateral spinal deformity often coupled with vertebral rotation with most of the cases presenting as idiopathic. ... Home / Shop / Imprints / Nova Medicine and Health / Scoliosis: Causes, Symptoms and Treatment. ...
King Type III Scoliosis. King Type III Scoliosis. (based on classification of King et al) assistance provided by Ben Allen Jr. ...
Core tip: This case report describes the first case of adolescent scoliosis associated with a large, paraspinous ... Paraspinous hemolymphangioma associated with adolescent scoliosis. World J Clin Cases 2015; 3(6): 514-518 [PMID: 26090372 DOI: ... a benign paraspinous vascular and lymphatic tumor may be responsible for scoliosis in a small number of patients. ...
CORDUS DELUXE Sciatica Pain, Herniated discs, Scoliosis, Low Back Pain and more. ... CORDUS DELUXE Sciatica Pain, Herniated discs, Scoliosis, Low Back Pain and more. ...
It is much less common than the type of scoliosis that begins in adolescence. Children with congenital scoliosis sometimes have ... Congenital scoliosis is a sideways curvature of the spine that is caused by a defect that is present at birth. ... Congenital scoliosis detected at an early age is one of the most challenging types of scoliosis to treat. The curves can be ... Types of Congenital Scoliosis. Incomplete Formation of Vertebrae. As the spine forms before birth, part of one vertebra (or ...
i have scoliosis in the lumber region of my back and i was wondering if it affects pregnancy and having sex. ... Im so glad I found this site because I have so many questions related to Scoliosis. I was diagnosed with Lumbar Scoliosis in ... Does Lumbar Scoliosis affect pregnancy and sex?. By damilola June 15, 2009 - 3:47am ... i have scoliosis in the lumber region of my back and i was wondering if it affects pregnancy and having sex. ...
Pig skin and scoliosis: how we created Frankensteins creature. Designer Ben Stones explains how he created the creature in ... The spinal cord has scoliosis, while another part has polio. Angela wanted to have his head is slightly disjointed and one leg ...
... your childs pediatrician may screen for scoliosis and recommend that your child get an X-ray to confirm a scoliosis or ... Scoliosis and Spine Program Where you take them matters.. Request an appointment with the only nationally ranked orthopedic ... If an X-ray confirms a diagnosis of scoliosis, you will then be referred to a specialist like Childrens for treatment options ... "Generally speaking, we do not see a spinal deformity like scoliosis being created by using a book bag. Even if its a heavy ...
Adolescent idiopathic scoliosis-a condition featuring curvature of the spine-affects tens of millions of children worldwide, ... The next step is to understand how BNC2 causes scoliosis and why it is so much more prevalent in women than in men. "The ... The discovery began with a genome-wide association study using more than ten thousand volunteers with and without scoliosis. ... "A functional SNP in BNC2 is associated with adolescent idiopathic scoliosis", American Journal of Human Genetics, doi: 10.1016/ ...
  • Recent longitudinal studies reveal that the most common form of the condition, late-onset idiopathic scoliosis, causes little physical impairment other than back pain and cosmetic concerns, even when untreated, with mortality rates similar to the general population. (wikipedia.org)
  • Older beliefs that untreated idiopathic scoliosis necessarily progresses into severe (cardiopulmonary) disability by old age have been refuted by later studies. (wikipedia.org)
  • An estimated 65% of scoliosis cases are idiopathic (cause unknown), about 15% are congenital, and about 10% are secondary to a neuromuscular disease. (wikipedia.org)
  • At least one gene, CHD7, has been associated with the idiopathic form of scoliosis. (wikipedia.org)
  • Several candidate gene studies have found associations between idiopathic scoliosis and genes mediating bone formation, bone metabolism, and connective tissue structure. (wikipedia.org)
  • Several genome-wide studies have identified a number of loci as significantly linked to idiopathic scoliosis. (wikipedia.org)
  • In 2006, idiopathic scoliosis was linked with three microsatellite polymorphisms in the MATN1 gene (encoding for matrilin 1, cartilage matrix protein). (wikipedia.org)
  • Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. (wikipedia.org)
  • Research suggests that Posterior Spinal Fusion (PSF) can be used to correct the more severe deformities caused by adolescent idiopathic scoliosis. (wikipedia.org)
  • What Causes Idiopathic Scoliosis? (kidshealth.org)
  • Idiopathic scoliosis is a bit of a medical mystery. (kidshealth.org)
  • Idiopathic scoliosis isn't caused by things like carrying a heavy backpack, bad posture, playing sports - or anything else you might do. (kidshealth.org)
  • The REFLECT Scoliosis Correction System is a non-fusion spinal device intended to treat idiopathic scoliosis , an abnormal curve of the spine that happens without a known cause, in children and adolescents whose bones have not fully matured. (fda.gov)
  • The REFLECT Scoliosis Correction System is indicated for people whose bones have not stopped growing (skeletally immature) and who require surgery to obtain and maintain correction of their progressive idiopathic scoliosis because use of a brace to correct their spinal curvature was not successful (failed bracing or intolerant to brace wear). (fda.gov)
  • Idiopathic scoliosis is the most common type of spinal deformity confronting orthopedic surgeons. (medscape.com)
  • Proper recognition and treatment of idiopathic scoliosis help optimize patient outcomes. (medscape.com)
  • In the past, terminology such as kyphoscoliosis was inappropriately used to describe certain patients with idiopathic scoliosis. (medscape.com)
  • Idiopathic scoliosis has a strong tendency to flatten the normal kyphosis of the thoracic spine. (medscape.com)
  • [ 5 ] Winter taught that idiopathic scoliosis is a hypokyphotic disease. (medscape.com)
  • Idiopathic scoliosis may present as a true kyphoscoliosis, but such a presentation is relatively rare. (medscape.com)
  • James is credited with classifying idiopathic scoliosis according to the age of the patient at the time of diagnosis. (medscape.com)
  • [ 8 ] In his classification system, children diagnosed when they are younger than 3 years have infantile idiopathic scoliosis, those diagnosed when they are aged 3-10 years have juvenile idiopathic scoliosis, and those diagnosed when they are older than 10 years have adolescent idiopathic scoliosis. (medscape.com)
  • For instance, Robinson and McMaster reviewed 109 patients with juvenile idiopathic scoliosis and found that nearly 90% of curves progressed and that almost 70% of these patients went on to require surgery. (medscape.com)
  • [ 9 ] These rates are much higher than the rates associated with other categories of idiopathic scoliosis. (medscape.com)
  • Adolescent idiopathic scoliosis (AIS) is 10 times more common in girls than boys! (srs.org)
  • Infantile idiopathic scoliosis is found in children ages 0 to 3. (srs.org)
  • Juvenile idiopathic scoliosis is found in in children ages 4 to 10. (srs.org)
  • Adolescent idiopathic scoliosis is found in adolescents ages 11 to 18. (srs.org)
  • Adult idiopathic scoliosis is found in patients older than 18. (srs.org)
  • Children can be screened at any age, although idiopathic scoliosis is more commonly discovered during a child's growth spurt (10 to 15 years old). (srs.org)
  • This is called idiopathic scoliosis. (medlineplus.gov)
  • Most people with idiopathic scoliosis do not need treatment. (medlineplus.gov)
  • A more recent article on adolescent idiopathic scoliosis is available. (aafp.org)
  • Adolescent idiopathic scoliosis is the most common form of scoliosis, affecting approximately 2% to 4% of adolescents. (aafp.org)
  • 1 - 3 , 6 Idiopathic scoliosis can be further classified by age of onset: infantile (birth to two years), juvenile (three to nine years), and adolescent (10 years and older). (aafp.org)
  • 1 - 3 , 6 Adolescent idiopathic scoliosis is the most common form. (aafp.org)
  • 3 , 12 If both parents have idiopathic scoliosis, their children are 50 times more likely to require scoliosis treatment compared with the general population. (aafp.org)
  • The U.S. Preventive Services Task Force (USPSTF) did not find good evidence that screening in asymptomatic adolescents detects idiopathic scoliosis at an earlier stage than no screening. (aafp.org)
  • It also found fair evidence that treating adolescent idiopathic scoliosis decreases pain and disability in only a small proportion of patients, and that treatment of adolescent idiopathic scoliosis detected through screening leads to moderate harms (e.g., unnecessary use of braces and referral). (aafp.org)
  • Scoliosis is a lateral spinal deformity often coupled with vertebral rotation with most of the cases presenting as idiopathic. (novapublishers.com)
  • Adolescent idiopathic scoliosis-a condition featuring curvature of the spine-affects tens of millions of children worldwide, but does not have a known cause. (riken.jp)
  • This review presents the state of the art according to the current evidence on nonoperative treatment for adolescent idiopathic scoliosis, focusing on bracing. (lww.com)
  • The definition of braces for the treatment of adolescent idiopathic scoliosis and a short history are provided. (lww.com)
  • In the August 2022 issue of Prosthetics and Orthotics International in the article by Grivas et al, "Nonoperative management of adolescent idiopathic scoliosis (AIS) using braces," the affiliation listed for the second author Stefano Negrini is incorrect. (lww.com)
  • Adolescent idiopathic scoliosis (AIS), for which the cause is unknown, is the most common type of scoliosis. (ibji.com)
  • However, timely treatment of adolescent idiopathic scoliosis is essential because, if the condition is left untreated, a spine curvature can develop into a significant deformity that may ultimately require surgery. (ibji.com)
  • Surgery for adolescent idiopathic scoliosis may be necessary to correct spine curvature when nonsurgical options fail or if the curve is greater than 45 to 50 degrees. (ibji.com)
  • This most common type of scoliosis is called "idiopathic" scoliosis and has no known cause and no known prevention. (youngmenshealthsite.org)
  • Scientists are studying idiopathic scoliosis, hoping to discover its cause. (youngmenshealthsite.org)
  • Children with idiopathic scoliosis are most often diagnosed between the ages of 10 and adulthood. (archildrens.org)
  • Scoliosis is usually idiopathic (cause unknown). (hss.edu)
  • Idiopathic scoliosis: The cause or origin is unknown. (hss.edu)
  • It develops most often in teenagers (known as adolescent idiopathic scoliosis). (hss.edu)
  • Adolescent idiopathic scoliosis is the type of scoliosis seen most frequently by spine surgeons, representing 80% of all spinal deformity cases. (hss.edu)
  • Join national pediatric scoliosis expert Michael Glotzbecker, MD for a virtual health talk featuring the latest information on idiopathic scoliosis including what it means to get a scoliosis diagnosis and what to do next. (uhhospitals.org)
  • The legal secretary explained that she had found out at 16 years old that she had the condition idiopathic scoliosis - which is sideways curving of the spine. (mamamia.com.au)
  • In most cases, scoliosis is idiopathic, meaning it has no known cause. (pthealth.ca)
  • The most common type of scoliosis is a condition known as adolescent idiopathic scoliosis. (epworth.org.au)
  • It largely presents when they are teenagers, and idiopathic means we actually don't have a real cause for the scoliosis," A/Prof Yang said. (epworth.org.au)
  • IMPORTANCE Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. (lu.se)
  • DESIGN, SETTING, AND PARTICIPANTS The Conservative Treatment for Adolescent Idiopathic Scoliosis (CONTRAIS) randomized clinical trial was conducted from January 10, 2013, through October 23, 2018, in 6 public hospitals across Sweden. (lu.se)
  • In contrast to the 2004 evidence review, which identified moderate harms associated with treating screen-detected adolescent idiopathic scoliosis at that time, including unnecessary bracing and referral to specialty care, the new systematic data review found adequate evidence that treatment with bracing may decrease scoliosis progression in adolescents with mild or moderate curvature severity and only limited available evidence on the harms of screening and treatment. (medscape.com)
  • Therefore, the USPSTF concludes that the current evidence is insufficient and that the balance of benefits and harms of screening for adolescent idiopathic scoliosis cannot be determined," the revised statement authors write. (medscape.com)
  • In an evaluation of the evidence "fit" with the biological understanding of scoliosis, the authors note that mild/moderate idiopathic scoliosis, defined as Cobb angle of less than 40° to 50°, is often asymptomatic in adolescence and does not progress substantially. (medscape.com)
  • Idiopathic scoliosis is lateral curvature of the spine. (msdmanuals.com)
  • Idiopathic scoliosis is the most common form of scoliosis and is present in 2 to 4% of children aged 10 to 16 years. (msdmanuals.com)
  • to accomplish this present study, a nine years old female subject with idiopathic thoracolumbar "S" scoliosis was evaluated. (bvsalud.org)
  • Scoliosis (PL: scolioses) is a condition in which a person's spine has a sideways curve. (wikipedia.org)
  • Scoliosis is typically classified as either structural in which the curve is fixed, or functional in which the underlying spine is normal. (wikipedia.org)
  • The signs of scoliosis can include: Uneven musculature on one side of the spine Rib prominence or a prominent shoulder blade, caused by rotation of the rib cage in thoracic scoliosis Uneven posture Heart and lung problems in severe cases Calcium deposits in the cartilage end-plate and sometimes in the disc itself People who have reached skeletal maturity are less likely to have a worsening case. (wikipedia.org)
  • Scoliosis causes a sideways curve of your backbone, or spine. (medlineplus.gov)
  • Scoliosis is when the vertebrae (the small bones in the spine) form a curved line instead of being straight. (kidshealth.org)
  • Kids who have had tumors or growths on their spine may also develop scoliosis. (kidshealth.org)
  • People with scoliosis have a side-to-side curve in the spine that can look like an "S" or a "C. (kidshealth.org)
  • Scoliosis (abnormal curvature of the spine) represents a disturbance of an otherwise well-organized 25-member intercalated series of spinal segments. (medscape.com)
  • Two-dimensional (2D) imaging systems (plain radiographs) remain somewhat limiting, and scoliosis is commonly defined as greater than 10° of lateral deviation of the spine from its central axis. (medscape.com)
  • Horizontal gaze palsy with progressive scoliosis (HGPPS) is a disorder that affects vision and also causes an abnormal curvature of the spine ( scoliosis ). (medlineplus.gov)
  • On an x-ray, the spine of a person with scoliosis looks more like an 'S' or a 'C' than a straight line. (srs.org)
  • If scoliosis is suspected following this simple examination, the doctor will usually order X-rays of the entire spine from the neck to the pelvis (back and side views). (srs.org)
  • Early Onset Scoliosis refers to spine curvature that is present before 10 years of age. (srs.org)
  • Simply defined, scoliosis is a sideways curve of the spine that measures greater than 10 degrees on X-ray. (srs.org)
  • Instead of a straight line down the middle of the back, a spine with scoliosis curves, sometimes looking like a letter 'C' or 'S.' Some of the bones in a scoliotic spine also may have rotated slightly, making the person's waist or shoulders appear uneven. (srs.org)
  • Scoliosis is an abnormal curving of the spine. (medlineplus.gov)
  • But people with scoliosis have a spine that curves too much. (medlineplus.gov)
  • 1 - 4 Scoliosis is defined as a lateral curve to the spine that is greater than 10 degrees with vertebral rotation. (aafp.org)
  • This site has educational material with graphics, pictures, and x-rays to show how scoliosis affects the spine. (epnet.com)
  • I'm not sure about scoliosis but my spine is pretty curved and I've never had an issue with it being effective. (babycenter.com)
  • Congenital scoliosis is a sideways curvature of the spine that is caused by a defect that was present at birth. (orthoinfo.org)
  • Even though congenital scoliosis is present at birth, it is sometimes impossible to see any spine problems until a child reaches adolescence. (orthoinfo.org)
  • In addition to scoliosis curves, a child's spine may also develop compensatory curves in order to maintain an upright posture. (orthoinfo.org)
  • This occurs when the spine tries to make up for a scoliosis curve by creating other curves in the opposite direction above, or below, the affected area. (orthoinfo.org)
  • A parent's natural instinct is to want to protect their children from developing back pain , or curves of the spine like scoliosis , and one major concern many parents have is posture. (choa.org)
  • While it is a real and relevant pain issue , the good news is that there is no evidence showing poor posture-as a result of technology use or otherwise-will lead to scoliosis or permanent curves of the spine. (choa.org)
  • While poor posture, caused by tech neck or heavy backpacks, may not directly lead to a scoliosis diagnosis, being proactive about your child's spine health is important to avoid fatigue and muscle pain. (choa.org)
  • Scoliosis, the curving of the spine from side to side, affects about 2% to 3% percent of the population, according to the American Association of Neurological Surgeons. (cnn.com)
  • John's surgeon, unable to treat him any further, recommended Dr. Lawrence Lenke, surgeon-in-chief at the Daniel and Jane Och Spine Hospital at NewYork-Presbyterian and a former president of the Scoliosis Research Society. (cnn.com)
  • Scoliosis is a condition causing the spine to curve sideways to the right or left. (ibji.com)
  • This fusion will stop the growth ini the curved part of the spine affected by scoliosis. (ibji.com)
  • Some babies are born with spinal defects that cause the spine to grow unevenly, a condition called congenital scoliosis or congenital kyphosis. (youngmenshealthsite.org)
  • This form of scoliosis makes the spine curve sideways, but what causes the condition is unknown. (archildrens.org)
  • Scoliosis is an abnormal curvature of the spine that can affect children and adults alike. (hss.edu)
  • Scoliosis is a condition of the spine in which the spine curves sideways in an "S" shape, either to the right or left side. (hss.edu)
  • Anteroposterior (front-to-back) view of the spine in standing position, demonstrating scoliosis (sideways curvature). (hss.edu)
  • The key symptom in all forms of scoliosis is a sideways curvature of the spine. (hss.edu)
  • A diagnosis for scoliosis made if a sideways curvature in the spine exceeds 10 degrees. (hss.edu)
  • Congenital scoliosis: Bones in the spine are abnormally curved sideways at birth. (hss.edu)
  • These conditions are all types of what is termed "structural scoliosis," where incorrectly formed bones create an S-curve in the spine that is fixed and cannot be straightened by adjusting body position. (hss.edu)
  • Nonstructural scoliosis" (also known as "functional scoliosis") is where the curvature is temporary and not caused by a malformed vertebrae in the spine but by a separate condition that affects posture, such as skeletal dysplasia or a leg length discrepancy . (hss.edu)
  • The curvature shown in the left image is the normal curve of the spine when it is viewed from the side (not scoliosis). (hss.edu)
  • Scoliosis comes from the Greek word skol, which means turn or twist and it's a type of condition that gives to the spine an S or C shape. (womenfitness.net)
  • Scoliosis is a condition that causes the spine to curve, resulting in an S-shaped spine. (ihanuman.com)
  • Exercise routines for scoliosis are typically low-impact and avoid exercises that put pressure on the spine. (ihanuman.com)
  • Scoliosis is the medical term for the sideways or side-to-side curvature of the spine in either an "s" or "c" shape. (pthealth.ca)
  • In nonstructural or functional scoliosis, the spine itself is normal and works properly but looks curved. (pthealth.ca)
  • When the curve of the spine is fixed and rigid and cannot be corrected, it's called structural scoliosis. (pthealth.ca)
  • Paula learned that her two oldest daughters, Daniela and Elisa, were both displaying signs of scoliosis, in which the spine curves, sometimes to a dangerous degree. (choa.org)
  • An Epworth spinal surgeon is concerned cases of curvature of the spine known as scoliosis may have been missed in teenagers throughout the pandemic. (epworth.org.au)
  • Participants were excluded from the spine scan if they reported a Harrington Rod in the spine for scoliosis. (cdc.gov)
  • The main reasons for completed, but invalid, spine scans were an insufficient scan area or partial scan, degenerative disease/severe scoliosis, and sclerotic spine/spinal fusion/laminectomy. (cdc.gov)
  • Symptoms associated with scoliosis can include: Pain in the back at the site of the curve, which may radiate to the legs Respiratory or cardiac problems in severe cases Constipation due to curvature causing "tightening" of the stomach, intestines, etc. (wikipedia.org)
  • Scoliosis is not painful, so if the curvature is not detected at birth, it can go undetected until there are obvious signs - which could be as late as adolescence. (orthoinfo.org)
  • Neuromuscular scoliosis: The curvature is a symptom of a separate, systemic condition affecting the nervous system and/or muscular system, such as cerebral palsy , neurofibromatosis , muscular dystrophy, paralysis. (hss.edu)
  • Your doctor will be able to provide recommendations based on his knowledge about which types of excercises would be best suited for you personally given unique circumstances surrounding your scoliosis diagnosis such as severity level (mild vs moderate), spinal curvature type (for example one shoulder higher than other shoulder), age group (adolescent vs adult) among other factors such as lifestyle habits such as smoking status etcetera. (ihanuman.com)
  • scoliosis is characterized by tridimensional modifications consisting of lateral curvature on the frontal plane, lateral rotation on the transverse plane, and rectification on the sagittal plane. (bvsalud.org)
  • Conditions known to cause scoliosis are congenital spinal column abnormalities (abnormally formed vertebrae present at birth), neurological disorders, muscular diseases, genetic conditions (e.g. (srs.org)
  • Congenital scoliosis: This type of scoliosis is present at birth. (medlineplus.gov)
  • Braces do not work for those with congenital or neuromuscular scoliosis. (medlineplus.gov)
  • Outlook for those with neuromuscular or congenital scoliosis varies. (medlineplus.gov)
  • Congenital scoliosis is difficult to treat and usually requires many surgeries. (medlineplus.gov)
  • She was born with congenital scoliosis, and her surgery is fast approaching. (gofundme.com)
  • Not only was she born with congenital scoliosis, she was also born with bilateral cleft feet. (gofundme.com)
  • Children with congenital scoliosis sometimes have other health issues, such as kidney or bladder problems. (orthoinfo.org)
  • Congenital scoliosis is often detected during the pediatrician's examination at birth because of a slight abnormality of the back. (orthoinfo.org)
  • Although the forward bending test can detect scoliosis, it cannot detect the presence of congenital abnormalities. (orthoinfo.org)
  • Once your doctor makes the diagnosis of congenital scoliosis, your child will be referred to a pediatric orthopaedic surgeon for specialized care and further tests. (orthoinfo.org)
  • Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway. (bvsalud.org)
  • Congenital scoliosis (CS) is a complex spinal malformation of unknown etiology with abnormal bone metabolism . (bvsalud.org)
  • Neuromuscular scoliosis: This type is caused by a nervous system problem that affects the muscles. (medlineplus.gov)
  • All were operated for neuromuscular scoliosis using posterior approach with pedicle screw fixation. (nih.gov)
  • Learn more about neuromuscular scoliosis . (hss.edu)
  • Most mild scoliosis curves don't need treatment. (kidshealth.org)
  • Surgery is an option used primarily for severe scoliosis (curves greater than 45 degrees) or for curves that do not respond to bracing. (medtronic.com)
  • Scoliosis is a condition of side-to-side spinal curves that measure greater than 10º. (srs.org)
  • If scoliosis is present, the doctor will measure the spine's curves and provide you with a number, in degrees, to help describe the scoliosis. (srs.org)
  • In many cases, scoliosis curves are small and do not require treatment. (ibji.com)
  • Early detection of abnormal spinal curves by school screening programs and pediatricians is intended to find scoliosis early enough to begin brace treatment and avoid surgery. (youngmenshealthsite.org)
  • If a doctor has defined a clear cause of the scoliosis, the curves will then be defined as either structural or nonstructural. (pthealth.ca)
  • Knowing the type of scoliosis helps health care providers treat it. (kidshealth.org)
  • This is the most common type of scoliosis. (kidshealth.org)
  • Experts don't know exactly why this type of scoliosis develops, but it runs in some families. (kidshealth.org)
  • This type of scoliosis happens when something goes wrong with the way some vertebrae developed before a baby was born. (kidshealth.org)
  • The treatment used depends on the type of scoliosis and how much more a child will grow. (kidshealth.org)
  • It occurs in only 1 in 10,000 newborns and is much less common than the type of scoliosis that begins in adolescence. (orthoinfo.org)
  • This type of scoliosis often creates complex curvatures, such as an overlapping kyphosis condition. (hss.edu)
  • Degenerative scoliosis: Affecting older adults, this type of scoliosis is caused by wear and tear on spinal joints or discs. (hss.edu)
  • This book follows a context-based approach to management of early-onset scoliosis (EOS) in countries with limited resources in education, finance, and research. (routledge.com)
  • First book to focus on countries with limited resources for the management of early onset scoliosis. (routledge.com)
  • He suffers from a severe form of Scoliosis, a progressive spinal deformity that requires immediate surgery, and Marfan Syndrome, a connective tiss. (niacouncil.org)
  • Although most youths with scoliosis will not develop clinical symptoms, scoliosis can progress to rib deformity and respiratory compromise, and can cause significant cosmetic problems and emotional distress for some patients. (aafp.org)
  • 1 - 3 , 6 , 7 Scoliosis usually does not cause problems, but sometimes leads to visible deformity, emotional distress, and respiratory impairment from rib deformity. (aafp.org)
  • Given the relationship between tumors and spinal deformity, a benign paraspinous vascular and lymphatic tumor may be responsible for scoliosis in a small number of patients. (wjgnet.com)
  • Generally speaking, we do not see a spinal deformity like scoliosis being created by using a book bag. (choa.org)
  • LOC is reaching out to those of you who have planned corrective spinal surgery for a scoliosis deformity and are facing the understandable postponement of this surgery. (londonorthotics.co.uk)
  • If your child is experiencing pain and stiffness, your child's pediatrician may screen for scoliosis and recommend that your child get an X-ray to confirm a scoliosis or kyphosis diagnosis. (choa.org)
  • If an X-ray confirms a diagnosis of scoliosis, you will then be referred to a specialist like Children's for treatment options . (choa.org)
  • Learn more about adult scoliosis by reading Scoliosis In Adults: Symptoms, Diagnosis and Treatments . (hss.edu)
  • The Schirmer sisters are awesome and a prime example of what good education and timely treatment can do to help a scoliosis diagnosis," says Dr. Flanagan. (choa.org)
  • Given teenagers were going out less due to the pandemic, the early signs of scoliosis may have been missed. (epworth.org.au)
  • In children age 11 through 18, it is called adolescent scoliosis. (medlineplus.gov)
  • This case report describes the first case of adolescent scoliosis associated with a large, paraspinous hemolymphangioma. (wjgnet.com)
  • What Are the Types of Scoliosis? (kidshealth.org)
  • There are several different types of scoliosis that affect infantile, children, juvenile and adolescents. (ibji.com)
  • The best way to prevent scoliosis from getting worse is through exercise and prevention. (ihanuman.com)
  • Some kids develop scoliosis because they have a long-term medical problem that affects the muscles or skeletal system. (kidshealth.org)
  • Back pain is common in people who develop scoliosis as an adult, but rare among children and adolescents. (hss.edu)
  • The revolutionary Peak Scoliosis Bracing System is an unloader brace specifically designed to relieve the pain associated with adult scoliosis. (chiroeco.com)
  • My scoliosis overcorrected by 10 degrees and I was able to reduce my scoliosis brace wear to 16 hours a day within 6 weeks. (londonorthotics.co.uk)
  • Health care providers treat scoliosis (sko-lee-OH-sis) with back braces or surgery when needed. (kidshealth.org)
  • People with severe scoliosis might need surgery. (kidshealth.org)
  • Some teens with severe scoliosis need a type of surgery called a spinal fusion . (kidshealth.org)
  • Previous surgery at the spinal levels where the scoliosis curve is located. (fda.gov)
  • Complications such as infection, nerve damage, blood loss, and bowel and bladder problems are some of the potential risks of any type of spinal surgery, including spinal fusion for the treatment of scoliosis. (medtronic.com)
  • Additional complications that may be associated with scoliosis surgery include loss of proper spinal balance, failure, of the bones to properly heal and fuse (pseudoarthrosis), instrumentation failure and vertebral degeneration in the levels adjacent to the fused section. (medtronic.com)
  • Please consult your doctor for a complete list of indications, warnings, precautions, adverse effects, clinical results, and other important medical information that pertains to scoliosis surgery. (medtronic.com)
  • Case series of 5 patients who developed resistant wound infection after scoliosis surgery. (nih.gov)
  • However, till date no reports have been found in the literature describing its use for the treatment of wound infection after scoliosis surgery, which has relatively longer and deeper wound. (nih.gov)
  • A total of 5 patients (2 females and 3 males) who developed wound infection after scoliosis correction surgery were included in this study. (nih.gov)
  • We would propose to use MDT for the treatment of wound infection after scoliosis surgery as an effective alternative to conventional treatment. (nih.gov)
  • Cox regression and generalized estimating equation models were used to estimate the effects of spinal surgery on survival and severe respiratory infection respectively in 140 females who developed severe scoliosis (Cobb angle ≥45°) before adulthood. (nih.gov)
  • In a series of Instagram snaps of x-ray images and her recovery, the former contestant (whose last name is Bennet) revealed that she underwent spinal fusion surgery to treat her scoliosis . (mamamia.com.au)
  • Surgery is a last resort, getting a spinal surgery is not the first route that people take when they have scoliosis, it's literally the last option. (mamamia.com.au)
  • Scoliosis is often the result of a growth spurt and many cases resolve themselves without the need for bracing or surgery. (pthealth.ca)
  • If surgery is not an option in the immediate future, and you are looking to prevent further progression of a scoliosis curve during a growth spurt, LOC can help. (londonorthotics.co.uk)
  • Only a very small percentage of scoliosis patients will need surgery. (epworth.org.au)
  • Ella's good friend Scarlett had undergone surgery to correct her Scoliosis 12 months before Ella was operated on. (epworth.org.au)
  • Over the last few years, Epworth has developed a program to help scoliosis patients recover quickly from surgery. (epworth.org.au)
  • 20 years ago, scoliosis patients were hospitalised for many weeks after surgery. (epworth.org.au)
  • In contrast, the Scoliosis Research Society, American Academy of Orthopaedic Surgeons, American Academy of Pediatrics, and Pediatric Orthopaedic Society of North America suggest that the potential benefit of detecting scoliosis early justifies screening programs, but greater care should be used in deciding which patients with positive screening results need further evaluation. (aafp.org)
  • Some severe cases of scoliosis can lead to diminishing lung capacity, pressure exerted on the heart, and restricted physical activities. (wikipedia.org)
  • Scoliosis is a common condition that affects many children and adolescents. (srs.org)
  • For decades, scoliosis screenings were a routine part of school physical examinations in adolescents. (aafp.org)
  • The U.S. Preventive Services Task Force and American Academy of Family Physicians recommend against routine scoliosis screening in asymptomatic adolescents, concluding that harm from screening outweighs the benefit because screenings expose many low-risk adolescents to unnecessary radiographs and referrals. (aafp.org)
  • Scoliosis is a condition commonly encountered in the primary care setting, affecting roughly 2% to 4% of adolescents. (aafp.org)
  • The U.S. Preventive Services Task Force and the American Academy of Family Physicians recommend against routine scoliosis screening in asymptomatic adolescents. (aafp.org)
  • Scoliosis is primarily diagnosed in children and adolescents. (hss.edu)
  • Children with scoliosis tend to go from being normally healthy, fit adolescents to facing a (significant) operation in a short space of time. (epworth.org.au)
  • In a revised recommendation statement on routine screening of adolescents for asymptomatic scoliosis, the US Preventive Services Task Force (USPSTF) no longer discourages screening but states there is insufficient evidence to determine the balance of benefits and harms. (medscape.com)
  • Mild scoliosis does not typically cause problems, but more severe cases can affect breathing and movement. (wikipedia.org)
  • People with mild scoliosis might only need checkups to see if the curve is getting worse. (medlineplus.gov)
  • People with mild scoliosis do well with braces. (medlineplus.gov)
  • Many people have mild scoliosis but are unaware of it and need no treatment for it. (youngmenshealthsite.org)
  • The following exercises are designed for people with mild scoliosis to begin an exercise program. (ihanuman.com)
  • Scoliosis can range from mild to severe, and is most common in growing children. (pthealth.ca)
  • How well a person with scoliosis does depends on the type, cause, and severity of the curve. (medlineplus.gov)
  • The clinical data suggests the REFLECT Scoliosis Correction System provides probable benefit to prevent spinal curve progression and avoid spinal fusion , the current standard-of-care treatment. (fda.gov)
  • A genetic factor has been implicated in the development and progression of scoliosis. (aafp.org)
  • 12 Saliva-based genetic markers could be a useful adjunct in predicting which patients are at risk of scoliosis progression. (aafp.org)
  • How scoliosis is treated varies depending on the cause, severity, and likelihood of progression. (pthealth.ca)
  • OBJECTIVE To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activity alone (PA) in preventing Cobb angle progression in moderate-grade AIS. (lu.se)
  • Measurement of the scoliotic curve is utilized to follow its evolving character and its muscular behavior, and the assessment performed through the electromyography can be an important indicative of predisposition regarding scoliosis progression. (bvsalud.org)
  • Find out more about what scoliosis is, who gets it, and what to expect during treatment. (kidshealth.org)
  • They see lots of teens with scoliosis and can decide if you need treatment. (kidshealth.org)
  • Nevertheless, the history of the recognition and treatment of scoliosis is rich with important lessons for the modern practitioner. (medscape.com)
  • Hippocrates' methods of scoliosis treatment focused primarily on spinal manipulation and traction. (medscape.com)
  • Once the presence of scoliosis is confirmed, your doctor will discuss treatment options with you or refer you to a specialist. (srs.org)
  • Males and females are about equally likely to have minor scoliosis of approximately 10 degrees, but females are five to 10 times more likely to progress to more severe disease, possibly needing treatment. (aafp.org)
  • In this book, the authors present topical research in the study of the causes, symptoms and treatment of scoliosis. (novapublishers.com)
  • To present maggot debridement therapy (MDT) as an effective alternative to the conventional treatment in postsurgical infection in scoliosis. (nih.gov)
  • Below you will find various relationships to , and potential clinical treatment approaches for scoliosis. (yinyanghouse.com)
  • It is critical to appreciate that in Chinese Medicine, treatment for "scoliosis" is rarely focused on the symptoms exclusively. (yinyanghouse.com)
  • The latest market analysis report published by Reports and Data, titled 'Global Scoliosis Treatment Market - Forecast to 2030,' thoroughly examines the Scoliosis Treatment industry to provide essential data & information for the targeted readers. (biospace.com)
  • The Scoliosis Treatment industry report emphasizes the current and upcoming market revenue growth opportunities and trends. (biospace.com)
  • The global Scoliosis Treatment market has significantly grown over the recent past and is expected to register rapid growth over the forecast period of 2021 to 2030. (biospace.com)
  • Revenue growth of the global Scoliosis Treatment market is significantly driven by factors such as the increasing prevalence of chronic diseases, rapid advancements in the healthcare and medical sector, high adoption of the latest tools and techniques and growing funds by several public and private sectors. (biospace.com)
  • Scoliosis and its treatment often interfere with an adolescent's self-image and self-esteem. (msdmanuals.com)
  • John, now 19, had been diagnosed at age 5 with what would become an extreme case of scoliosis and kyphosis. (cnn.com)
  • In children age 3 and younger, it is called infantile scoliosis. (medlineplus.gov)
  • Because of all the possible combinations of curvatures, scoliosis can be very different in different people. (youngmenshealthsite.org)
  • Learn more about Pediatric Scoliosis . (uhhospitals.org)
  • Meet the Pediatric Scoliosis Specialists . (uhhospitals.org)
  • Auctus Surgical's vertebral body-tethering system to treat pediatric scoliosis with a nonfusion, dynamic approach has been designated a breakthrough device by the FDA. (fdanews.com)
  • The Scoliosis Research Society (SRS) Annual Meeting is a forum for the realization of the Society's mission and goals, the improvement of patient care for those with spinal deformities. (srs.org)
  • Scoliosis most often affects girls. (medlineplus.gov)
  • i have scoliosis in the lumber region of my back and i was wondering if it affects pregnancy and having sex. (empowher.com)
  • Scoliosis affects girls much more than boys, by a ratio of about 8 to 1. (hss.edu)
  • Scoliosis mainly affects teenage girls, and often runs in families. (epworth.org.au)
  • Typically, scoliosis is first noticed by a child's pediatrician, family member or school nurse. (hss.edu)
  • If your child has scoliosis then there is a risk this can progress as your child grows, particularly during an adolescent growth spurt. (londonorthotics.co.uk)
  • Orthopedic specialists (doctors and other providers who treat bone and muscle problems) group scoliosis into types. (kidshealth.org)
  • The goal for primary care physicians is to identify patients who are at risk of developing problems from scoliosis, without overtesting or overreferring patients who are unlikely to have further problems. (aafp.org)
  • Epworth Richmond is one of the largest private hospitals taking care of scoliosis patients, with a specialist team of doctors, surgeons, nurses and allied health staff working together to care for children with scoliosis. (epworth.org.au)
  • A group of 51 patients diagnosed with interstitial lung diseases, bronchiectasis, asthma and scoliosis were studied. (who.int)
  • Une étude rétrospective a été menée à Riyad (Arabie saoudite) pour connaître l'impact de la rééducation pulmonaire d'une part sur les paramètres respiratoires d'un groupe de patients en consultation externe pour des affections pulmonaires chroniques autres que la bronchopneumopathie chronique obstructive (BPCO) et d'autre part sur leur utilisation des soins de santé. (who.int)
  • of pulmonary rehabilitation in to the asthma, interstitial lung diseases (ILD) Specific exercises for the upper and management of patients with CLD or scoliosis. (who.int)
  • In children age 4 through 10, it is called juvenile scoliosis. (medlineplus.gov)
  • This video provides an animated illustration of on adult and juvenile scoliosis. (hss.edu)