Pulmonary injury following the breathing in of toxic smoke from burning materials such as plastics, synthetics, building materials, etc. This injury is the most frequent cause of death in burn patients.
Burns of the respiratory tract caused by heat or inhaled chemicals.
Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
A species of sheep, Ovis aries, descended from Near Eastern wild forms, especially mouflon.
Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
'Smoke' is a complex mixture of gases, fine particles, and volatile compounds, generally produced by combustion of organic substances, which can contain harmful chemicals known to have adverse health effects.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
The circulation of the BLOOD through the LUNGS.
The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER.
'Fires' is not a recognized medical term for a symptom, diagnosis, or condition in patients.
Specialized hospital facilities which provide intensive care for burn patients.
Carboxyhemoglobin is a form of hemoglobin in which the heme group is chemically bonded to carbon monoxide, reducing its ability to transport oxygen and leading to toxic effects when present in high concentrations.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Toxic asphyxiation due to the displacement of oxygen from oxyhemoglobin by carbon monoxide.
The exposure to potentially harmful chemical, physical, or biological agents by inhaling them.
The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.

Role of L-selectin in physiological manifestations after burn and smoke inhalation injury in sheep. (1/134)

The effects of a monoclonal antibody against L-selectin [leukocyte adhesion molecule (LAM)1-3] on microvascular fluid flux were determined in conscious sheep subjected to a combined injury of 40% third-degree burn and smoke inhalation. This combined injury induced a rapid increase in systemic prefemoral lymph flow (sQlymph) from the burned area and a delayed-onset increase in lung lymph flow. The initial increase in sQlymph was associated with an elevation of the lymph-to-plasma oncotic pressure ratio; consequently, it leads to a predominant increase in the systemic soft tissue permeability index (sPI). In an untreated control group, the increased sPI was sustained beyond 24 h after injury. Pretreatment with LAM1-3 resulted in earlier recovery from the increased sPI, although the initial responses in sQlymph and sPI were identical to those in the nontreatment group. The delayed-onset lung permeability changes were significantly attenuated by pretreatment with LAM1-3. These findings indicate that both leukocyte-dependent and -independent mechanisms are involved in the pathogenesis that occurs after combined injury with burn and smoke inhalation.  (+info)

Early alterations of lung injury following acute smoke exposure and 21-aminosteroid treatment. (2/134)

In a simulated fire-related smoke exposure protocol, New Zealand white rabbits were utilized to investigate the potential effects of the 21-aminosteroid (lazaroid) analog U75412E on the early events of acute lung injury. Inhalation of a total of 1.6 mg/kg U75412E aerosolized at a rate of 1.53 mg/min at 0.5 hr after smoke exposure significantly attenuated the extent of lung injury at 1 hr, as evidenced by decreased bronchoalveolar lavage (BAL) concentration of total protein, 6-keto-prostaglandin F1-alpha, and blood gas defect. Histopathologic examination demonstrated that the lazaroid significantly attenuated smoke-induced lung injury as evidenced by a decrease in wet lung/body weight ratio, necrosis, and sloughing of airway epithelial cells. Electron microscopy showed that the lazaroid decreased smoke-induced interstitial edema and the vacuolization of alveolar type II epithelium (21.6 +/- 9.7 vs 8.5 +/- 3.6 vacuoled blebs/cell, smoke only vs smoke + lazaroid). However, U75412E did not attenuate smoke-induced changes in BAL concentration of tumor necrosis factor-alpha, total cell count, and granulocyte percentage. These observations suggest that U75412E may exert its action through cooperative mechanisms, such as the modulation of arachidonic acid metabolism, in addition to its characterized antioxidative effects.  (+info)

Increased group IV cytosolic phospholipase A2 activity in lungs of sheep after smoke inhalation injury. (3/134)

Increased phospholipase A2 (PLA2) activity was measured in cytosolic fractions of lungs from sheep exposed to smoke from burning cotton or to synthetic smoke consisting of carbon and acrolein, a cotton smoke toxin. Three peaks of PLA2 activity were identified by heparin-Sepharose chromatography. The heparin-nonbinding PLA2 activity was twofold higher in the extracts from lungs exposed to smoke than in normal lungs. This activity was identified as the group IV 85-kDa cytosolic PLA2 (cPLA2). The activities of the forms of PLA2 that bound to heparin did not change after smoke exposure. Those activities showed a pH optimum of 9.0, required a millimolar Ca2+ concentration for full activity, and were inhibited by 5 mM dithiothreitol. One activity eluted at an NaCl concentration typical for group Ib and V PLA2 and had the expected substrate specificity. The other form of lung PLA2 that bound heparin was a group II PLA2. Lung myeloperoxidase activity increased progressively with increased exposure to smoke. cPLA2 was identified in sheep neutrophils. With 30 breaths of smoke exposure, there was an increase in cPLA2 activity without a difference in immunoreactivity on Western blot, indicating that the increased activity was not due to increased amounts of protein. In conclusion, smoke induces increases in resident lung cell cPLA2 activity that is likely responsible for eicosanoid production, leading to lung inflammation and bronchoconstriction.  (+info)

The "Let's Get Alarmed!" initiative: a smoke alarm giveaway programme. (4/134)

OBJECTIVES: To reduce fires and fire related injuries by increasing the prevalence of functioning smoke alarms in high risk households. SETTING: The programme was delivered in an inner London area with above average material deprivation and below average smoke alarm ownership. The target population included low income and rental households and households with elderly persons or young children. METHODS: Forty wards, averaging 4000 households each, were randomised to intervention or control status. Free smoke alarms and fire safety information were distributed in intervention wards by community groups and workers as part of routine activities and by paid workers who visited target neighbourhoods. Recipients provided data on household age distribution and housing tenure. Programme costs were documented from a societal perspective. Data are being collected on smoke alarm ownership and function, and on fires and related injuries and their costs. RESULTS: Community and paid workers distributed 20,050 smoke alarms, potentially sufficient to increase smoke alarm ownership by 50% in intervention wards. Compared with the total study population, recipients included greater proportions of low income and rental households and households including children under 5 years or adults aged 65 and older. Total programme costs were 145,087 Pounds. CONCLUSIONS: It is possible to implement a large scale smoke alarm giveaway programme targeted to high risk households in a densely populated, multicultural, materially deprived community. The programme's effects on the prevalence of installed and functioning alarms and the incidence of fires and fire related injuries, and its cost effectiveness, are being evaluated as a randomized controlled trial.  (+info)

House fire injury prevention update. Part II. A review of the effectiveness of preventive interventions. (5/134)

OBJECTIVE: To evaluate and summarize the house fire injury prevention literature. METHODS: MEDLINE (1983 to March 1997) was searched by keyword: fire, burn, etiology, cause, prevention, epidemiology, and smoke detector/alarm. ERIC (1966 to March 1997) and PSYCLIT (1974 to June 1997) were searched by keyword: as above, and safety, skills, education, and training. Other sources included references of retrieved publications, review articles, and books; Injury Prevention hand search; government documents; and internet sources. Sources relevant to residential fire injury prevention were selected, evaluated, and summarized. RESULTS: Forty three publications were selected for review, including seven randomized controlled trials, nine quasiexperiments, two natural experiments, 21 prospective cohort studies, two cross sectional surveys, one case report, and one program evaluation. These studies examined the following types of interventions: school (9), preschool (1), and community based educational programs (5); fire response training programs for children (7), blind adolescents (2), and mentally retarded adults (5) and children (1); office based counseling (4); home inspection programs (3); smoke detector giveaway campaigns (5); and smoke detector legislation (1). CONCLUSIONS: This review of house fire prevention interventions underscores the importance of program evaluation. There is a need for more rigorous evaluation of educational programs, particularly those targeted at schools. An evidence based, coordinated approach to house fire injury prevention is critical, given current financial constraints and the potential for program overload for communities and schools.  (+info)

Systematic review of controlled trials of interventions to promote smoke alarms. (6/134)

AIMS: To evaluate the effects of promotion of residential smoke alarms. METHODS: Electronic databases, conference proceedings, and bibliographies were systematically searched, and investigators and organisations were contacted, in order to identify controlled trials evaluating interventions designed to promote residential smoke alarms. The following were assessed: smoke alarm acquisition, ownership, and function; fires; burns; and fire related injuries. Odds ratios (OR) were estimated by meta analysis of randomised trials. RESULTS: A total of 26 trials were identified, of which 13 were randomised. Overall, counselling and educational interventions had only a modest effect on the likelihood of owning an alarm (OR = 1.26; 95% confidence interval (CI): 0.87 to 1.81) or having a functional alarm (OR = 1.19; 95% CI: 0.85 to 1.66). Counselling as part of primary care child health surveillance had greater effects on ownership (OR = 1.93; 95% CI: 1.04 to 3.58) and function (OR = 1. 72; 95% CI: 0.78 to 3.78). Results were sensitive to trial quality, however, and effects on fire related injuries were not reported. In two non-randomised trials, direct provision of free alarms significantly increased functioning alarms and reduced fire related injuries. Media and community education showed little benefit in non-randomised trials. CONCLUSION: Counselling as part of child health surveillance may increase smoke alarm ownership and function, but its effects on injuries are unevaluated. Community smoke alarm give away programmes apparently reduce fire related injuries, but these trials were not randomised and results must be interpreted cautiously. Further efforts to promote smoke alarms in primary care or through give away programmes should be evaluated by adequately designed randomised controlled trials measuring injury outcomes.  (+info)

Profile of the pediatric burn patient at the Schneider Children's Medical Center of Israel. (7/134)

BACKGROUND: Burn trauma occurs mostly in young children. Burn injury in the pediatric age group has multiple-aspect sequelae. OBJECTIVES: To characterize the profile of the injured pediatric burn patient, thus targeting the most vulnerable pediatric group. METHODS: Between 1 January and 31 December 1996, a total of 9,235 pediatric patients were admitted for various traumatic injuries (burns, lacerations, fractures, etc.) to the Emergency Medicine Department of Schneider Children's Medical Center. We conducted a retrospective study of the patients' charts, including demographic data, which were stored in a computerized database, for statistical evaluation. The characteristics of pediatric burn patients were examined and compared with other pediatric trauma patients. RESULTS: Of the total patient population, 282 (3.1%) suffered from burns (37% females, 63% males). The most frequent burn injury was scald burn (58%). The pediatric group that was most exposed to burns was 13-18 month old males. CONCLUSIONS: Having identified the high risk group among the pediatric burn patients, we suggest that prevention programs be directed towards this group in order to reduce further risk of burn injury.  (+info)

Prior exposure to aged and diluted sidestream cigarette smoke impairs bronchiolar injury and repair. (8/134)

The bronchiolar injury/repair response to naphthalene (NA) in mice includes acute distal airway epithelial injury that is followed by epithelial proliferation and redifferentiation, which result in repair of the epithelium within 14 days. To test whether prior exposure to aged and diluted sidestream cigarette smoke (TS) would alter the injury/repair response of the airway epithelium, adult mice were exposed to either filtered air (FA) or smoke for 5 days before injection with either corn oil carrier (CO) or naphthalene. Mice were killed 1 and 14 days after naphthalene injury. Lung and lobar bronchus were examined and measured using high-resolution epoxyresin sections. The control group (FACOFA) that was exposed to filtered air/corn oil/filtered air contained airway epithelium similar to untreated controls at all airway levels. The group exposed to tobacco smoke/corn oil/filtered air (TSCOFA) contained some rounded cells in the small airways and some expansion of the lateral intercellular space in the larger airways. Necrotic or vacuolated cells were not observed. As expected, the epithelium in the group exposed to filtered air/naphthalene/filtered air (FANAFA) contained many light-staining vacuolated Clara cells and squamated ciliated cells within distal bronchioles during the acute injury phase. Repair (including redifferentiation of epithelial cells and restoration of epithelial thickness) was nearly complete 14 days after injury. The extent of Clara cell injury, as assessed in lobar bronchi, was not different between the four groups. Although the FANAFA group contained greater initial injury in the distal airways at 1 day, the group exposed to tobacco smoke/naphthalene/filtered air (TSNAFA) had the least amount of epithelial repair at 14 days after naphthalene treatment; many terminal bronchioles contained abundant squamated undifferentiated epithelium. We conclude that tobacco smoke exposure prior to injury (1) does not change the target site or target cell type of naphthalene injury, since Clara cells in terminal bronchioles are still selectively injured; (2) results in slightly diminished acute injury from naphthalene in distal bronchioles; and (3) delays bronchiolar epithelial repair.  (+info)

Smoke inhalation injury is a type of damage that occurs to the respiratory system when an individual breathes in smoke, most commonly during a fire. This injury can affect both the upper and lower airways and can cause a range of symptoms, including coughing, wheezing, shortness of breath, and chest pain.

Smoke inhalation injury can also lead to more severe complications, such as chemical irritation of the airways, swelling of the throat and lungs, and respiratory failure. In some cases, it can even be fatal. The severity of the injury depends on several factors, including the duration and intensity of the exposure, the individual's underlying health status, and the presence of any pre-existing lung conditions.

Smoke inhalation injury is caused by a combination of thermal injury (heat damage) and chemical injury (damage from toxic substances present in the smoke). The heat from the smoke can cause direct damage to the airways, leading to inflammation and swelling. At the same time, the chemicals in the smoke can irritate and corrode the lining of the airways, causing further damage.

Some of the toxic substances found in smoke include carbon monoxide, cyanide, and various other chemicals released by burning materials. These substances can interfere with the body's ability to transport oxygen and can cause metabolic acidosis, a condition characterized by an excessively acidic environment in the body.

Treatment for smoke inhalation injury typically involves providing supportive care to help the individual breathe more easily, such as administering oxygen or using mechanical ventilation. In some cases, medications may be used to reduce inflammation and swelling in the airways. Severe cases of smoke inhalation injury may require hospitalization and intensive care.

Inhalation burns, also known as respiratory or pulmonary burns, refer to damage to the airways and lungs caused by inhaling hot gases, smoke, steam, or toxic fumes. This type of injury can occur during a fire or other thermal incidents and can result in significant morbidity and mortality.

Inhalation burns are classified into three categories based on the location and severity of the injury:

1. Upper airway burns: These involve the nose, throat, and voice box (larynx) and are usually caused by inhaling hot gases or steam. Symptoms may include singed nasal hairs, soot in the nose or mouth, coughing, wheezing, and difficulty speaking or swallowing.
2. Lower airway burns: These involve the trachea, bronchi, and bronchioles and are usually caused by inhaling smoke or toxic fumes. Symptoms may include coughing, chest pain, shortness of breath, and wheezing.
3. Systemic burns: These occur when toxic substances are absorbed into the bloodstream and can affect multiple organs. Symptoms may include nausea, vomiting, confusion, and organ failure.

Inhalation burns can lead to complications such as pneumonia, respiratory failure, and acute respiratory distress syndrome (ARDS). Treatment typically involves providing oxygen therapy, removing secretions from the airways, and administering bronchodilators and corticosteroids to reduce inflammation. Severe cases may require intubation and mechanical ventilation.

Prevention of inhalation burns includes avoiding smoke-filled areas during a fire, staying close to the ground where the air is cooler and cleaner, and using appropriate respiratory protection devices when exposed to toxic fumes or gases.

Burns are injuries to tissues caused by heat, electricity, chemicals, friction, or radiation. They are classified based on their severity:

1. First-degree burns (superficial burns) affect only the outer layer of skin (epidermis), causing redness, pain, and swelling.
2. Second-degree burns (partial-thickness burns) damage both the epidermis and the underlying layer of skin (dermis). They result in redness, pain, swelling, and blistering.
3. Third-degree burns (full-thickness burns) destroy the entire depth of the skin and can also damage underlying muscles, tendons, and bones. These burns appear white or blackened and charred, and they may be painless due to destroyed nerve endings.

Immediate medical attention is required for second-degree and third-degree burns, as well as for large area first-degree burns, to prevent infection, manage pain, and ensure proper healing. Treatment options include wound care, antibiotics, pain management, and possibly skin grafting or surgery in severe cases.

A domestic sheep (Ovis aries) is not a medical term, but it is an animal species that humans keep and breed for a variety of purposes, including meat, wool, and milk production. While the term "sheep" may appear in medical contexts, such as in discussions of zoonotic diseases (diseases transmissible between animals and humans), the specific definition you are looking for is not medical in nature. Domestic sheep are social herbivores that prefer to eat short grasses and can be found in various parts of the world. They have been domesticated for thousands of years, making them one of the earliest animals to be domesticated by humans.

Hydrogen Cyanide (HCN) is a chemical compound with the formula H-C≡N. It is a colorless, extremely poisonous and flammable liquid that has a bitter almond-like odor in its pure form. However, not everyone can detect its odor, as some people lack the ability to smell it, which makes it even more dangerous. It is soluble in water and alcohol, and its aqueous solution is called hydrocyanic acid or prussic acid.

Hydrogen Cyanide is rapidly absorbed by inhalation, ingestion, or skin contact, and it inhibits the enzyme cytochrome c oxidase, which is essential for cellular respiration. This leads to rapid death due to hypoxia (lack of oxygen) at the cellular level. It is used industrially in large quantities as a pesticide, fumigant, and chemical intermediate, but it also has significant potential for use as a chemical weapon.

In the medical field, Hydrogen Cyanide poisoning can be treated with high-concentration oxygen, sodium nitrite, and sodium thiosulfate, which help to restore the function of cytochrome c oxidase and enhance the elimination of cyanide from the body.

'Smoke' is not typically defined in a medical context, but it can be described as a mixture of small particles and gases that are released when something burns. Smoke can be composed of various components including carbon monoxide, particulate matter, volatile organic compounds (VOCs), benzene, toluene, styrene, and polycyclic aromatic hydrocarbons (PAHs). Exposure to smoke can cause a range of health problems, including respiratory symptoms, cardiovascular disease, and cancer.

In the medical field, exposure to smoke is often referred to as "secondhand smoke" or "passive smoking" when someone breathes in smoke from another person's cigarette, cigar, or pipe. This type of exposure can be just as harmful as smoking itself and has been linked to a range of health problems, including respiratory infections, asthma, lung cancer, and heart disease.

I apologize, but "sheep" is not a term that has a medical definition. It is a common animal with the scientific name Ovis aries. If you have any medical or health-related questions, I would be happy to try and help answer those for you.

Pulmonary circulation refers to the process of blood flow through the lungs, where blood picks up oxygen and releases carbon dioxide. This is a vital part of the overall circulatory system, which delivers nutrients and oxygen to the body's cells while removing waste products like carbon dioxide.

In pulmonary circulation, deoxygenated blood from the systemic circulation returns to the right atrium of the heart via the superior and inferior vena cava. The blood then moves into the right ventricle through the tricuspid valve and gets pumped into the pulmonary artery when the right ventricle contracts.

The pulmonary artery divides into smaller vessels called arterioles, which further branch into a vast network of tiny capillaries in the lungs. Here, oxygen from the alveoli diffuses into the blood, binding to hemoglobin in red blood cells, while carbon dioxide leaves the blood and is exhaled through the nose or mouth.

The now oxygenated blood collects in venules, which merge to form pulmonary veins. These veins transport the oxygen-rich blood back to the left atrium of the heart, where it enters the systemic circulation once again. This continuous cycle enables the body's cells to receive the necessary oxygen and nutrients for proper functioning while disposing of waste products.

Pulmonary gas exchange is the process by which oxygen (O2) from inhaled air is transferred to the blood, and carbon dioxide (CO2), a waste product of metabolism, is removed from the blood and exhaled. This process occurs in the lungs, primarily in the alveoli, where the thin walls of the alveoli and capillaries allow for the rapid diffusion of gases between them. The partial pressure gradient between the alveolar air and the blood in the pulmonary capillaries drives this diffusion process. Oxygen-rich blood is then transported to the body's tissues, while CO2-rich blood returns to the lungs to be exhaled.

I believe there may be some confusion in your question. "Fires" is not a medical term that I am aware of. In a general context, a fire refers to the rapid oxidation of a material in the chemical process of combustion, releasing heat, light, and various reaction products. If you are asking about a specific medical term or condition, could you please provide more context or clarify your question? I'm here to help!

Burn units are specialized sections of hospitals that provide comprehensive care to patients with significant burn injuries. These units are staffed with a multidisciplinary team of healthcare professionals who have expertise in treating burn injuries, including plastic surgeons, critical care specialists, nurses, therapists, and psychologists. The team provides various services such as wound care, infection prevention, pain management, physical therapy, occupational therapy, and psychological support to help patients recover from their injuries. Burn units may also conduct research and engage in education and training related to burn care.

Carboxyhemoglobin (COHb) is a form of hemoglobin that has bonded with carbon monoxide (CO), a colorless, odorless gas. Normally, hemoglobin in red blood cells binds with oxygen (O2) to carry it throughout the body. However, when exposed to CO, hemoglobin preferentially binds with it, forming carboxyhemoglobin, which reduces the amount of oxygen that can be carried by the blood. This can lead to hypoxia (lack of oxygen in tissues) and potentially serious medical consequences, including death. Carbon monoxide exposure can occur from sources such as smoke inhalation, vehicle exhaust, or faulty heating systems.

A lung is a pair of spongy, elastic organs in the chest that work together to enable breathing. They are responsible for taking in oxygen and expelling carbon dioxide through the process of respiration. The left lung has two lobes, while the right lung has three lobes. The lungs are protected by the ribcage and are covered by a double-layered membrane called the pleura. The trachea divides into two bronchi, which further divide into smaller bronchioles, leading to millions of tiny air sacs called alveoli, where the exchange of gases occurs.

Hemodynamics is the study of how blood flows through the cardiovascular system, including the heart and the vascular network. It examines various factors that affect blood flow, such as blood volume, viscosity, vessel length and diameter, and pressure differences between different parts of the circulatory system. Hemodynamics also considers the impact of various physiological and pathological conditions on these variables, and how they in turn influence the function of vital organs and systems in the body. It is a critical area of study in fields such as cardiology, anesthesiology, and critical care medicine.

Carbon monoxide (CO) poisoning is a medical condition that occurs when carbon monoxide gas is inhaled, leading to the accumulation of this toxic gas in the bloodstream. Carbon monoxide is a colorless, odorless, and tasteless gas produced by the incomplete combustion of fossil fuels such as natural gas, propane, oil, wood, or coal.

When carbon monoxide is inhaled, it binds to hemoglobin, the protein in red blood cells responsible for carrying oxygen throughout the body. This binding forms carboxyhemoglobin (COHb), which reduces the oxygen-carrying capacity of the blood and leads to hypoxia, or insufficient oxygen supply to the body's tissues and organs.

The symptoms of carbon monoxide poisoning can vary depending on the level of exposure and the duration of exposure. Mild to moderate CO poisoning may cause symptoms such as headache, dizziness, weakness, nausea, vomiting, chest pain, and confusion. Severe CO poisoning can lead to loss of consciousness, seizures, heart failure, respiratory failure, and even death.

Carbon monoxide poisoning is a medical emergency that requires immediate treatment. Treatment typically involves administering high-flow oxygen therapy to help eliminate carbon monoxide from the body and prevent further damage to tissues and organs. In some cases, hyperbaric oxygen therapy may be used to accelerate the elimination of CO from the body.

Prevention is key in avoiding carbon monoxide poisoning. It is essential to ensure that all fuel-burning appliances are properly maintained and ventilated, and that carbon monoxide detectors are installed and functioning correctly in homes and other enclosed spaces.

Inhalation exposure is a term used in occupational and environmental health to describe the situation where an individual breathes in substances present in the air, which could be gases, vapors, fumes, mist, or particulate matter. These substances can originate from various sources, such as industrial processes, chemical reactions, or natural phenomena.

The extent of inhalation exposure is determined by several factors, including:

1. Concentration of the substance in the air
2. Duration of exposure
3. Frequency of exposure
4. The individual's breathing rate
5. The efficiency of the individual's respiratory protection, if any

Inhalation exposure can lead to adverse health effects, depending on the toxicity and concentration of the inhaled substances. Short-term or acute health effects may include irritation of the eyes, nose, throat, or lungs, while long-term or chronic exposure can result in more severe health issues, such as respiratory diseases, neurological disorders, or cancer.

It is essential to monitor and control inhalation exposures in occupational settings to protect workers' health and ensure compliance with regulatory standards. Various methods are employed for exposure assessment, including personal air sampling, area monitoring, and biological monitoring. Based on the results of these assessments, appropriate control measures can be implemented to reduce or eliminate the risks associated with inhalation exposure.

"Inhalation administration" is a medical term that refers to the method of delivering medications or therapeutic agents directly into the lungs by inhaling them through the airways. This route of administration is commonly used for treating respiratory conditions such as asthma, COPD (chronic obstructive pulmonary disease), and cystic fibrosis.

Inhalation administration can be achieved using various devices, including metered-dose inhalers (MDIs), dry powder inhalers (DPIs), nebulizers, and soft-mist inhalers. Each device has its unique mechanism of delivering the medication into the lungs, but they all aim to provide a high concentration of the drug directly to the site of action while minimizing systemic exposure and side effects.

The advantages of inhalation administration include rapid onset of action, increased local drug concentration, reduced systemic side effects, and improved patient compliance due to the ease of use and non-invasive nature of the delivery method. However, proper technique and device usage are crucial for effective therapy, as incorrect usage may result in suboptimal drug deposition and therapeutic outcomes.

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Points and Pearls Digest for the journal Emergency Department Management of Smoke Inhalation Injury in Adults ... Emergency Department Management of Smoke Inhalation Injury in Adults. .fas.fa-lock { color: #154fa5 !important; } Below is a ... Pathophysiology, research challenges, and clinical management of smoke inhalation injury. Lancet. 2016;388(10052):1437-1446. ( ... Home , All Topics , Emergency Department Management of Smoke Inhalation Injury in Adults ...
Background: Smoke inhalation injury refers to airway and lung parenchyma injury and general chemical damage caused by inhaling ... The aim of this study was to explore the oxidative stress mechanism of cotton smoke inhalation-induced pulmonary injury in a ... Conclusion: In rats with cotton smoke inhalation-induced pulmonary injury, the increased iNOS mRNA transcription can cause ... Oxidative stress in a rat model of cotton smoke inhalation-induced pulmonary injury ...
Smoke Inhalation - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version. ... To assess the extent of injury due to smoke inhalation in people with significant symptoms, doctors may pass a flexible viewing ... Symptoms of Smoke Inhalation Symptoms of carbon monoxide poisoning include headache, nausea, drowsiness, confusion, and coma. ... However, if the smoke contains certain poisonous chemicals or is unusually dense or if inhalation is prolonged, serious ...
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... of smoke inhalation injury prolongs the length of hospital stay 2.5-fold compared to those without smoke inhalation injury (24 ... Enkhbaatar P. Enkhbaatar P Enkhbaatar, Perenlei. "Thermal Lung Injury and Acute Smoke Inhalation." Fishmans Pulmonary Diseases ... Enkhbaatar P. Enkhbaatar P Enkhbaatar, Perenlei.Thermal Lung Injury and Acute Smoke Inhalation. In: Grippi MA, Elias JA, ... Enkhbaatar P. Enkhbaatar P Enkhbaatar, Perenlei. (2015). Thermal lung injury and acute smoke inhalation. Grippi MA, Elias JA, ...
"Smoke inhalation injury". BJA Education. 15 (3): 143-148. doi:10.1093/bjaceaccp/mku017. Smoke Inhalation Injury. Elsevier ... This can cause smoke inhalation injury (subtype of acute inhalation injury) which is damage to the respiratory tract caused by ... Smoke inhalation injury is the most common cause of death in fire victims. Fire victims with both burns to their body and smoke ... Victims of smoke inhalation injury can present with cough, difficulty breathing, low oxygen saturation, smoke debris and/or ...
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SMOKE INHALATION INJURY CAUSES MYOCARDIAL DEPRESSION IN SHEEP K. Sugi, M.D.; K. Sugi, M.D. ... K. Sugi, J. Newald, L. D. Traber, J. P. Maguire, D. N. Herndon, G. Schlag, D. L. Traber; SMOKE INHALATION INJURY CAUSES ... Thromboxane A 2 Synthase Inhibition by OKY-046 Prevents Cardiopulmonary Dysfunction after Ovine Smoke Inhalation Injury ... fluorodeoxyglucose Uptake and Ventilation-Perfusion Mismatch in the Early Stage of Experimental Acute Smoke Inhalation ...
Smoke Inhalation see Inhalation Injuries * Smokeless Tobacco * Smoking * Smoking and Youth * Smoking Cessation see Quitting ...
Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep. In: American Journal of ... Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep. American Journal of Physiology- ... Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep. / Shimoda, K.; Murakami, K.; ... title = "Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep", ...
Posted in: Having a Burn Injury Lawyer, Smoke Inhalation Injury and Third Degree Burns ... Recall of Mini Coopers for Fire Hazard Reminds Us That Cars Can Cause Severe Burns and Smoke Inhalation Injury. By Larry Kramer ... If you or someone you know suffers an injury such as third degree burns or smoke inhalation, you should call Kramer & Pollack ... SEARCH BURN INJURY RESOURCE CENTER. Search on Burn Injury Resource Center Search. ...
... the Fire Smoke Coalition launched the first Smoke Inhalation Treatment Database for use by EMTs, first responders and medical ... If you or someone you know suffers a burn injury or a smoke inhalation injury, you should call Kramer & Pollack LLP in Mineola ... On October 6, 2011, the Fire Smoke Coalition launched the first Smoke Inhalation Treatment Database for use by EMTs, first ... to establish a national database of smoke inhalation injuries, medical complications and deaths linked to HCN. ...
... injury from smoke inhalation to the upper airway, lower airway, or lungs. ... On the nonfatal injury report request page, you can request the number of injuries from a specific cause and intent of injury ... Reporting nonfatal injury data by the underlying cause of injury is consistent with how fatal injury data are reported. This ... 5.2.2 Data Element: Intent of Injury. Intent of Injury: Whether an injury was caused by an act carried out on purpose by ...
Many more people suffered burns, smoke inhalation and other injuries.. It was so hot all around me, I felt like my shirt was ... In western Canada, a series of unusually severe fires sent clouds of smoke over vast swaths of the U.S., polluting the air. ... Fantasy Football Waiver Wire Pickups, Week 13: Looking for help with 6 teams on bye and more injuries. ...
Smoke-inhalation; Injuries; Injury-prevention; Traumatic-injuries; Toxic-gases; Poison-gases; Accident-prevention; Accident- ... educate homeowners on the importance of installing and maintaining smoke detectors on every level of their home and keeping ...
Doctors see minor fractures, crush injuries and smoke inhalation. Extreme heat is also linked with aggression and violence, and ... More intense wildfires spew dangerous smoke into the air, as documented in the western US this year. And hotter days make more ... Extreme weather events, including hurricanes, floods and wildfires, often cause physical injuries. ...
Three consumers have reported injuries due to smoke inhalation.. Sold At: Best Buy, Costco, The Home Depot, Lowes and other ... Incidents/Injuries: Samsung has received 51 reports of smoking, melting, overheating or fire involving the washers; 10 of which ... Deaths, injuries, and property damage from consumer product-related incidents cost the nation more than $1 trillion annually. ... CPSCs work to ensure the safety of consumer products has contributed to a decline in the rate of injuries associated with ...
Five crew members suffered minor injuries, including smoke inhalation and heat exhaustion. They were treated by the ships ... Crew members spotted smoke around 5 p.m. local time and discovered a fire in the exhaust stack and adjacent spaces, according ... The USS Carney wasnt damaged in the attack and no injuries were reported on board. ... The USS Carney wasnt damaged in the attack and no injuries were reported on board. ...
One firefighter suffered a minor smoke-inhalation injury, authorities said.. The fire erupted Monday about a mile from the area ... as sunny skies gave way to smoke-fueled gloom. The South Coast Air Quality Management District issued a smoke advisory for a ... Smoke from the blaze could be seen for miles in all directions, prompting warnings from health officials for people to remain ... Eastbound lanes of the Riverside Freeway were closed at 11:50 a.m. at Imperial Highway because of the smoke and reduced ...
Aspergillosis in Amazon Parrots After Corticosteroid Therapy for Smoke-inhalation Injury Frank A. L M. Verstappen, Gerry M. ... KEYWORDS: aspergillosis, Aspergillus fumigatus, smoke inhalation, Avian, Amazon parrots, Amazona aestiva aestiva. ... were presented within 8 hours of exposure to fire and smoke. The parrots exhibited variable degrees of dyspnea that developed ... followed by bony fixation that provides sufficient stability to allow unimpeded healing with minimal soft-tissue injury. We ...
The other injuries included smoke inhalation and heat stroke. This story was originally reported on wxyz.com. ...
Lung injury from smoke inhalation. Paediatr Respir Rev 2006;7(2):123-8. ... Acute inhalation injury. Clin Chest Med 2002;23(4):707-15.. *Borak J, Diller WF. Phosgene exposure: mechanisms of injury and ... www.uptodate.com/contents/inhalation-injury-from-heat-smoke-or-chemical-irritants?search=chlorine%20gas&source=search_result& ... Respiratory management of inhalation injury. Burns 2007;33(1):2-13.. *Lee AS, Mellins RB, Lee AS, Mellins RB. ...
Another person was also taken to SGH for smoke inhalation injuries, said SCDF. ... Another person was assessed by an ambulance crew and was conveyed to SGH for smoke inhalation injuries. Neighbours and ... "Firefighters donned breathing apparatus sets and proceeded cautiously into the smoke-logged unit. The fire, which involved ... Fire breaks out at industrial building near Pioneer Road; no injuries reported ...
However, Mdm Goh died of her injuries and complications that arose from the smoke inhalation on Dec 9, 2019. ... She died in hospital more than a month later of smoke inhalation injuries. ... Mdm Gohs son, Mr Maverick Chia Yat Hwee, who was 30 at the time, also smoked. However, he said he smoked inside or outside the ... They also said that they smoked within their homes and did not throw their cigarette butts over the corridor ledges. ...
... eight more died of injuries; and 24 others suffered non-fatal injuries, primarily from smoke inhalation. The battleship flew ... The enemy planes retired without penetrating the smoke screen, and the vessels ceased making smoke and stood down their watches ... Twice during the 2d dog watch, South Dakota made smoke and opened fire to starboard with her 5-inch guns against unidentified ... A thick yellow-orange cloud of ether smoke poured from the trunk descending to sick bay, choking and blinding men in its path. ...
Firefighters are susceptive to burns, smoke inhalation, and injuries from disintegrating structures. They may suffer heat ... They are also eligible to receive disability payments in case of injury on the job. Firefighters also have job security and ...
Effects of rolling inhibition on smoke inhalation injury. Burns. 2003 Jun;29(4):307-14. Cetin C, Ozyilmaz M, Bayçu C, Köse AA, ...

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