Rare neoplasms of mesenchymal origin, usually benign, and most commonly involving the PLEURA (see SOLITARY FIBROUS TUMOR, PLEURAL). They also are found in extrapleural sites.
A rare neoplasm, usually benign, derived from mesenchymal fibroblasts located in the submesothelial lining of the PLEURA. It spite of its various synonyms, it has no features of mesothelial cells and is not related to malignant MESOTHELIOMA or asbestos exposure.
Neoplasms composed of fibrous tissue, the ordinary connective tissue of the body, made up largely of yellow or white fibers. The concept does not refer to neoplasms located in fibrous tissue.
A tumor composed of spindle cells with a rich vascular network, which apparently arises from pericytes, cells of smooth muscle origin that lie around small vessels. Benign and malignant hemangiopericytomas exist, and the rarity of these lesions has led to considerable confusion in distinguishing between benign and malignant variants. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1364)
A benign tumor of fibrous or fully developed connective tissue.
Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms.
A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
Retroperitoneal neoplasms are a diverse group of tumors that originate in the retroperitoneal space, which is the area behind the peritoneum and includes the kidneys, adrenal glands, pancreas, and major blood vessels.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.
Surgical incision into the chest wall.
A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.
Surgical operations on the nose and nasal cavity.
Glycoproteins found on immature hematopoietic cells and endothelial cells. They are the only molecules to date whose expression within the blood system is restricted to a small number of progenitor cells in the bone marrow.
Tumors or cancer of the PAROTID GLAND.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Facial neoplasms are abnormal growths or tumors that develop in the facial region, which can be benign or malignant, originating from various cell types including epithelial, glandular, connective tissue, and neural crest cells.
A mixed mesenchymal tumor composed of two or more mesodermal cellular elements not commonly associated, not counting fibrous tissue as one of the elements. Mesenchymomas are widely distributed in the body and about 75% are malignant. (Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
The part of the face that is below the eye and to the side of the nose and mouth.
Tumors or cancer of the pelvic region.
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
Neoplasms of the bony orbit and contents except the eyeball.
An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000.
A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
Endoscopic surgery of the pleural cavity performed with visualization via video transmission.
GRAY MATTER located in the dorsomedial part of the MEDULLA OBLONGATA associated with the solitary tract. The solitary nucleus receives inputs from most organ systems including the terminations of the facial, glossopharyngeal, and vagus nerves. It is a major coordinator of AUTONOMIC NERVOUS SYSTEM regulation of cardiovascular, respiratory, gustatory, gastrointestinal, and chemoreceptive aspects of HOMEOSTASIS. The solitary nucleus is also notable for the large number of NEUROTRANSMITTERS which are found therein.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A species of FLAVIVIRUS, one of the Japanese encephalitis virus group (ENCEPHALITIS VIRUSES, JAPANESE), found in Australia and New Guinea. It causes a fulminating viremia resembling Japanese encephalitis (ENCEPHALITIS, JAPANESE).

Solitary fibrous tumor of the male breast: a case report and review of the literature. (1/74)

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Lack of a common or characteristic cytogenetic anomaly in solitary fibrous tumor. (2/74)

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Solitary fibrous tumor of the orbit: CT and MR imaging findings. (3/74)

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A dumbbell-shaped solitary fibrous tumor of the cervical spinal cord. (4/74)

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Myxoid solitary fibrous tumor of the retroperitoneum: MRI findings with the pathologic correlation. (5/74)

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Solitary fibrous tumor of the trachea: CT findings with a pathological correlation. (6/74)

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Solitary fibrous tumor of the pancreas: imaging findings. (7/74)

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Solitary fibrous tumor of the pancreas: case report with cytologic and surgical pathology correlation and review of the literature. (8/74)

CONTEXT: Solitary fibrous tumor is an uncommon spindle cell tumor which can occur in a variety of locations. Four cases of pancreatic solitary fibrous tumor have been reported in the literature. CASE REPORT: We report the fifth case of pancreatic solitary fibrous tumor in a 78-year-old woman who presented with back pain and weight loss. Imaging studies were suggestive of an endocrine tumor. Endoscopic ultrasound with fine needle aspiration was performed and revealed a benign mesenchymal tumor, which is the first successful report of cytology on a pancreatic solitary fibrous tumor. The patient underwent a distal pancreatectomy with resection of the mass which was diagnosed as solitary fibrous tumor, supported by immunohistochemical studies showing positivity for CD99, vimentin, bcl-2, and CD34. CONCLUSION: Diagnosing pancreatic solitary fibrous tumor is challenging due to its rarity, nonspecific clinical presentation, and difficulty to be radiologically distinguished from other pancreatic lesions. These issues as well as the prior four cases are discussed.  (+info)

Solitary fibrous tumors (SFTs) are rare type of slow-growing neoplasms that typically arise from the pleura, the thin layer of tissue that covers the lungs. However, they can also occur in other locations throughout the body such as the peritoneum, meninges, and deep soft tissues.

SFTs are composed of spindle-shaped cells arranged in a patternless architecture, with a variably collagenous stroma. They are usually well-circumscribed and encapsulated, although they can become invasive in some cases. The cellularity of SFTs varies from low to high, and the tumors can contain staghorn vessels, which are dilated blood vessels with a branching pattern.

The majority of SFTs are benign, but approximately 10-20% of them can be malignant or have aggressive behavior, with potential for local recurrence and distant metastasis. The diagnosis of SFT is usually made by histopathological examination of the tumor tissue, which shows characteristic features such as CD34 and Bcl-2 positivity on immunohistochemistry.

Treatment options for SFTs include surgical resection with wide margins, radiation therapy, and systemic therapy with chemotherapy or targeted agents. The choice of treatment depends on the location, size, and behavior of the tumor, as well as the patient's overall health status. Regular follow-up is necessary to monitor for recurrence or metastasis.

A Solitary Fibrous Tumor (SFT) is a rare type of soft tissue neoplasm that can occur in various locations throughout the body. When it develops in the pleura, which is the thin layer of tissue that surrounds the lungs, it is referred to as a "Solitary Fibrous Tumor, Pleural."

These tumors are typically slow-growing and can range in size from a few centimeters to over 20 cm in diameter. They are usually asymptomatic and are often discovered incidentally on chest X-rays or CT scans performed for other reasons. However, larger tumors may cause symptoms such as cough, chest pain, or shortness of breath.

SFTs, Pleural are typically well-circumscribed, encapsulated masses that can be removed surgically with curative intent. The histological features of SFTs include a patternless architecture with alternating hypocellular and hypercellular areas, along with a prominent network of thin-walled blood vessels.

Immunohistochemical staining is often used to confirm the diagnosis of SFT, with positivity for CD34 and STAT6 being characteristic features. The prognosis for patients with SFTs, Pleural is generally good, with a low risk of recurrence following surgical resection. However, some cases may exhibit more aggressive behavior, and long-term follow-up is recommended.

Neoplasms of fibrous tissue are abnormal growths or tumors that originate from fibroblasts, the cells responsible for producing connective tissue in the body. These neoplasms can be benign or malignant (cancerous). Benign fibrous neoplasms include fibromas and fibrohistiocytic tumors, while malignant fibrous neoplasms are called fibrosarcomas. Fibrosarcomas are aggressive tumors that invade surrounding tissues and can metastasize (spread) to other parts of the body.

Fibrous tissue neoplasms can occur in any part of the body, but they are most commonly found in the soft tissues such as muscles, tendons, and ligaments. They can also develop in bones, where they are called osteosarcomas. Symptoms of fibrous tissue neoplasms depend on their size and location, but may include a painless mass or swelling, limited mobility, or pain if the tumor is pressing on nerves or blood vessels.

Diagnosis of fibrous tissue neoplasms typically involves imaging tests such as X-rays, CT scans, or MRI scans, followed by a biopsy to confirm the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up care is important to monitor for recurrence or metastasis.

Hemangiopericytoma is a rare type of soft tissue sarcoma, which is a cancer that develops from the cells that surround blood vessels. It specifically arises from the pericytes, which are cells that help regulate blood flow in capillaries. Hemangiopericytomas typically form in the membranes surrounding the brain and spinal cord (meninges), but they can also occur in other parts of the body such as the lungs, abdomen, or extremities.

These tumors usually grow slowly, but they can become aggressive and spread to other parts of the body (metastasize). Symptoms depend on the location of the tumor, but may include headaches, seizures, weakness, or numbness in the arms or legs. Diagnosis typically involves imaging tests like MRI or CT scans, followed by a biopsy to confirm the presence of cancer cells. Treatment usually consists of surgical removal of the tumor, often accompanied by radiation therapy and/or chemotherapy to help prevent recurrence or spread of the disease.

A fibroma is a benign (non-cancerous) tumor that consists primarily of fibrous or connective tissue. It can occur in various parts of the body, including the skin, mouth, and internal organs. The term "fibroma" is often used to describe any benign fibrous growth, but there are specific types of fibromas such as dermatofibroma (found in the skin), oral fibroma (found in the mouth), and benign fibrous histiocytoma (found in soft tissues).

It's important to note that while fibromas are generally harmless, they can cause discomfort or problems depending on their size and location. If a fibroma is causing issues or there's concern about its growth or malignancy, it should be evaluated by a healthcare professional for potential removal or further assessment.

Pleural neoplasms refer to abnormal growths or tumors that develop in the pleura, which is the thin, double layered membrane that surrounds the lungs and lines the inside of the chest wall. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Malignant pleural neoplasms are often associated with lung cancer, mesothelioma, or metastasis from other types of cancer. They can cause symptoms such as chest pain, cough, shortness of breath, and weight loss. Diagnosis typically involves imaging tests like X-rays or CT scans, followed by biopsy to confirm the type of tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

A lipoma is a common, benign (non-cancerous) soft tissue growth. It is composed of adipose or fatty tissue and typically found just beneath the skin, but they can also occur deeper within the body. Lipomas are usually round, moveable, and painless, although they may cause discomfort if they grow large enough to put pressure on nearby nerves or if they're located in a sensitive area. They generally grow slowly over time. Surgical removal is an option if the lipoma becomes bothersome or grows significantly in size. It's important to note that while lipomas are typically harmless, any new lumps or bumps should be evaluated by a healthcare professional to confirm the diagnosis and rule out other more serious conditions.

Retroperitoneal neoplasms refer to abnormal growths or tumors that develop in the retroperitoneal space. This is the area located behind the peritoneum, which is the membrane that lines the abdominal cavity and covers the abdominal organs. The retroperitoneal space contains several vital structures such as the kidneys, adrenal glands, pancreas, aorta, and lymphatic vessels.

Retroperitoneal neoplasms can be benign or malignant (cancerous). Malignant retroperitoneal neoplasms are often aggressive and can invade surrounding tissues and organs, leading to various complications. Common types of retroperitoneal neoplasms include lymphomas, sarcomas, and metastatic tumors from other primary sites. Symptoms may vary depending on the size and location of the tumor but can include abdominal or back pain, weight loss, and swelling in the legs. Diagnosis typically involves imaging studies such as CT scans or MRI, followed by a biopsy to determine the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.

The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.

CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.

In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.

CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.

In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.

Soft tissue neoplasms refer to abnormal growths or tumors that develop in the soft tissues of the body. Soft tissues include muscles, tendons, ligaments, fascia, nerves, blood vessels, fat, and synovial membranes (the thin layer of cells that line joints and tendons). Neoplasms can be benign (non-cancerous) or malignant (cancerous), and their behavior and potential for spread depend on the specific type of neoplasm.

Benign soft tissue neoplasms are typically slow-growing, well-circumscribed, and rarely spread to other parts of the body. They can often be removed surgically with a low risk of recurrence. Examples of benign soft tissue neoplasms include lipomas (fat tumors), schwannomas (nerve sheath tumors), and hemangiomas (blood vessel tumors).

Malignant soft tissue neoplasms, on the other hand, can grow rapidly, invade surrounding tissues, and may metastasize (spread) to distant parts of the body. They are often more difficult to treat than benign neoplasms and require a multidisciplinary approach, including surgery, radiation therapy, and chemotherapy. Examples of malignant soft tissue neoplasms include sarcomas, such as rhabdomyosarcoma (arising from skeletal muscle), leiomyosarcoma (arising from smooth muscle), and angiosarcoma (arising from blood vessels).

It is important to note that soft tissue neoplasms can occur in any part of the body, and their diagnosis and treatment require a thorough evaluation by a healthcare professional with expertise in this area.

The pleura is the medical term for the double-layered serous membrane that surrounds the lungs and lines the inside of the chest cavity. The two layers of the pleura are called the parietal pleura, which lines the chest cavity, and the visceral pleura, which covers the surface of the lungs.

The space between these two layers is called the pleural cavity, which contains a small amount of lubricating fluid that allows the lungs to move smoothly within the chest during breathing. The main function of the pleura is to protect the lungs and facilitate their movement during respiration.

Thoracotomy is a surgical procedure that involves making an incision on the chest wall to gain access to the thoracic cavity, which contains the lungs, heart, esophagus, trachea, and other vital organs. The incision can be made on the side (lateral thoracotomy), back (posterolateral thoracotomy), or front (median sternotomy) of the chest wall, depending on the specific surgical indication.

Thoracotomy is performed for various indications, including lung biopsy, lung resection, esophagectomy, heart surgery, and mediastinal mass removal. The procedure allows the surgeon to directly visualize and access the organs within the thoracic cavity, perform necessary procedures, and control bleeding if needed.

After the procedure, the incision is typically closed with sutures or staples, and a chest tube may be placed to drain any accumulated fluid or air from the pleural space around the lungs. The patient will require postoperative care and monitoring in a hospital setting until their condition stabilizes.

A rare disease, also known as an orphan disease, is a health condition that affects fewer than 200,000 people in the United States or fewer than 1 in 2,000 people in Europe. There are over 7,000 rare diseases identified, and many of them are severe, chronic, and often life-threatening. The causes of rare diseases can be genetic, infectious, environmental, or degenerative. Due to their rarity, research on rare diseases is often underfunded, and treatments may not be available or well-studied. Additionally, the diagnosis of rare diseases can be challenging due to a lack of awareness and understanding among healthcare professionals.

Nasal surgical procedures, also known as nasal surgery or rhinoplasty, refer to various surgical operations performed on the nose. These procedures can be either functional (to improve breathing) or cosmetic (to change the appearance of the nose). Some common nasal surgical procedures include:

1. Septoplasty: a surgical procedure to correct a deviated septum, which is the partition between the two nostrils. This procedure helps to improve airflow through the nose and alleviate breathing difficulties.
2. Turbinate reduction: a procedure that reduces the size of the turbinates (structures inside the nasal passages that help warm, humidify, and filter the air we breathe) to improve nasal breathing.
3. Rhinoplasty: a cosmetic procedure that reshapes or resizes the nose to achieve a more desirable appearance. This can involve changing the shape of the cartilage, bone, or soft tissue in the nose.
4. Nasal polyp removal: a procedure to remove nasal polyps, which are non-cancerous growths that can obstruct the nasal passages and cause breathing difficulties.
5. Sinus surgery: a procedure to open up blocked sinuses and improve drainage. This can be done through various techniques, including endoscopic sinus surgery, balloon sinuplasty, or traditional sinus surgery.
6. Nose reconstruction: a procedure to repair or reconstruct the nose after trauma, cancer, or other medical conditions that have caused damage to the nose.

These are just a few examples of nasal surgical procedures. The specific type of procedure will depend on the individual patient's needs and goals.

CD34 is a type of antigen that is found on the surface of certain cells in the human body. Specifically, CD34 antigens are present on hematopoietic stem cells, which are immature cells that can develop into different types of blood cells. These stem cells are found in the bone marrow and are responsible for producing red blood cells, white blood cells, and platelets.

CD34 antigens are a type of cell surface marker that is used in medical research and clinical settings to identify and isolate hematopoietic stem cells. They are also used in the development of stem cell therapies and transplantation procedures. CD34 antigens can be detected using various laboratory techniques, such as flow cytometry or immunohistochemistry.

It's important to note that while CD34 is a useful marker for identifying hematopoietic stem cells, it is not exclusive to these cells and can also be found on other cell types, such as endothelial cells that line blood vessels. Therefore, additional markers are often used in combination with CD34 to more specifically identify and isolate hematopoietic stem cells.

Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.

Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.

The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.

Tumor markers are substances that can be found in the body and their presence can indicate the presence of certain types of cancer or other conditions. Biological tumor markers refer to those substances that are produced by cancer cells or by other cells in response to cancer or certain benign (non-cancerous) conditions. These markers can be found in various bodily fluids such as blood, urine, or tissue samples.

Examples of biological tumor markers include:

1. Proteins: Some tumor markers are proteins that are produced by cancer cells or by other cells in response to the presence of cancer. For example, prostate-specific antigen (PSA) is a protein produced by normal prostate cells and in higher amounts by prostate cancer cells.
2. Genetic material: Tumor markers can also include genetic material such as DNA, RNA, or microRNA that are shed by cancer cells into bodily fluids. For example, circulating tumor DNA (ctDNA) is genetic material from cancer cells that can be found in the bloodstream.
3. Metabolites: Tumor markers can also include metabolic products produced by cancer cells or by other cells in response to cancer. For example, lactate dehydrogenase (LDH) is an enzyme that is released into the bloodstream when cancer cells break down glucose for energy.

It's important to note that tumor markers are not specific to cancer and can be elevated in non-cancerous conditions as well. Therefore, they should not be used alone to diagnose cancer but rather as a tool in conjunction with other diagnostic tests and clinical evaluations.

Facial neoplasms refer to abnormal growths or tumors that develop in the tissues of the face. These growths can be benign (non-cancerous) or malignant (cancerous). Facial neoplasms can occur in any of the facial structures, including the skin, muscles, bones, nerves, and glands.

Benign facial neoplasms are typically slow-growing and do not spread to other parts of the body. Examples include papillomas, hemangiomas, and neurofibromas. While these tumors are usually harmless, they can cause cosmetic concerns or interfere with normal facial function.

Malignant facial neoplasms, on the other hand, can be aggressive and invasive. They can spread to other parts of the face, as well as to distant sites in the body. Common types of malignant facial neoplasms include basal cell carcinoma, squamous cell carcinoma, and melanoma.

Treatment for facial neoplasms depends on several factors, including the type, size, location, and stage of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. It is important to seek medical attention promptly if you notice any unusual growths or changes in the skin or tissues of your face.

Mesenchymoma is a very rare type of tumor that contains a mixture of different types of mesenchymal tissues, such as muscle, fat, bone, cartilage, or fibrous tissue. It typically occurs in children and young adults, and can be found in various parts of the body, including the head, neck, retroperitoneum (the area behind the abdominal cavity), and the limbs.

Mesenchymomas are usually slow-growing and may not cause any symptoms until they reach a large size. Treatment typically involves surgical removal of the tumor, but radiation therapy or chemotherapy may also be used in some cases. The prognosis for mesenchymoma depends on several factors, including the location and size of the tumor, the patient's age and overall health, and the specific types of tissue that are present in the tumor.

Skull base neoplasms refer to abnormal growths or tumors located in the skull base, which is the region where the skull meets the spine and where the brain connects with the blood vessels and nerves that supply the head and neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells in this area, including bone, nerve, glandular, and vascular tissue.

Skull base neoplasms can cause a range of symptoms depending on their size, location, and growth rate. Some common symptoms include headaches, vision changes, hearing loss, facial numbness or weakness, difficulty swallowing, and balance problems. Treatment options for skull base neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. The specific treatment plan will depend on the type, size, location, and stage of the tumor, as well as the patient's overall health and medical history.

Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.

A "cheek" is the fleshy, muscular area of the face that forms the side of the face below the eye and above the jaw. It contains the buccinator muscle, which helps with chewing by moving food to the back teeth for grinding and also assists in speaking and forming facial expressions. The cheek also contains several sensory receptors that allow us to perceive touch, temperature, and pain in this area of the face. Additionally, there is a mucous membrane lining inside the mouth cavity called the buccal mucosa which covers the inner surface of the cheek.

Pelvic neoplasms refer to abnormal growths or tumors located in the pelvic region. These growths can be benign (non-cancerous) or malignant (cancerous). They can originate from various tissues within the pelvis, including the reproductive organs (such as ovaries, uterus, cervix, vagina, and vulva in women; and prostate, testicles, and penis in men), the urinary system (kidneys, ureters, bladder, and urethra), the gastrointestinal tract (colon, rectum, and anus), as well as the muscles, nerves, blood vessels, and other connective tissues.

Malignant pelvic neoplasms can invade surrounding tissues and spread to distant parts of the body (metastasize). The symptoms of pelvic neoplasms may vary depending on their location, size, and type but often include abdominal or pelvic pain, bloating, changes in bowel or bladder habits, unusual vaginal bleeding or discharge, and unintentional weight loss. Early detection and prompt treatment are crucial for improving the prognosis of malignant pelvic neoplasms.

Meningeal neoplasms, also known as malignant meningitis or leptomeningeal carcinomatosis, refer to cancerous tumors that originate in the meninges, which are the membranes covering the brain and spinal cord. These tumors can arise primarily from the meningeal cells themselves, although they more commonly result from the spread (metastasis) of cancer cells from other parts of the body, such as breast, lung, or melanoma.

Meningeal neoplasms can cause a variety of symptoms, including headaches, nausea and vomiting, mental status changes, seizures, and focal neurological deficits. Diagnosis typically involves imaging studies (such as MRI) and analysis of cerebrospinal fluid obtained through a spinal tap. Treatment options may include radiation therapy, chemotherapy, or surgery, depending on the type and extent of the tumor. The prognosis for patients with meningeal neoplasms is generally poor, with a median survival time of several months to a year.

Orbital neoplasms refer to abnormal growths or tumors that develop in the orbit, which is the bony cavity that contains the eyeball, muscles, nerves, fat, and blood vessels. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells within the orbit.

Orbital neoplasms can cause a variety of symptoms depending on their size, location, and rate of growth. Common symptoms include protrusion or displacement of the eyeball, double vision, limited eye movement, pain, swelling, and numbness in the face. In some cases, orbital neoplasms may not cause any noticeable symptoms, especially if they are small and slow-growing.

There are many different types of orbital neoplasms, including:

1. Optic nerve glioma: a rare tumor that arises from the optic nerve's supportive tissue.
2. Orbital meningioma: a tumor that originates from the membranes covering the brain and extends into the orbit.
3. Lacrimal gland tumors: benign or malignant growths that develop in the lacrimal gland, which produces tears.
4. Orbital lymphangioma: a non-cancerous tumor that arises from the lymphatic vessels in the orbit.
5. Rhabdomyosarcoma: a malignant tumor that develops from the skeletal muscle cells in the orbit.
6. Metastatic tumors: cancerous growths that spread to the orbit from other parts of the body, such as the breast, lung, or prostate.

The diagnosis and treatment of orbital neoplasms depend on several factors, including the type, size, location, and extent of the tumor. Imaging tests, such as CT scans and MRI, are often used to visualize the tumor and determine its extent. A biopsy may also be performed to confirm the diagnosis and determine the tumor's type and grade. Treatment options include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

Vimentin is a type III intermediate filament protein that is expressed in various cell types, including mesenchymal cells, endothelial cells, and hematopoietic cells. It plays a crucial role in maintaining cell structure and integrity by forming part of the cytoskeleton. Vimentin is also involved in various cellular processes such as cell division, motility, and intracellular transport.

In addition to its structural functions, vimentin has been identified as a marker for epithelial-mesenchymal transition (EMT), a process that occurs during embryonic development and cancer metastasis. During EMT, epithelial cells lose their polarity and cell-cell adhesion properties and acquire mesenchymal characteristics, including increased migratory capacity and invasiveness. Vimentin expression is upregulated during EMT, making it a potential target for therapeutic intervention in cancer.

In diagnostic pathology, vimentin immunostaining is used to identify mesenchymal cells and to distinguish them from epithelial cells. It can also be used to diagnose certain types of sarcomas and carcinomas that express vimentin.

Hypoglycemia is a medical condition characterized by an abnormally low level of glucose (sugar) in the blood. Generally, hypoglycemia is defined as a blood glucose level below 70 mg/dL (3.9 mmol/L), although symptoms may not occur until the blood sugar level falls below 55 mg/dL (3.0 mmol/L).

Hypoglycemia can occur in people with diabetes who are taking insulin or medications that increase insulin production, as well as those with certain medical conditions such as hormone deficiencies, severe liver illnesses, or disorders of the adrenal glands. Symptoms of hypoglycemia include sweating, shaking, confusion, rapid heartbeat, and in severe cases, loss of consciousness or seizures.

Hypoglycemia is typically treated by consuming fast-acting carbohydrates such as fruit juice, candy, or glucose tablets to rapidly raise blood sugar levels. If left untreated, hypoglycemia can lead to serious complications, including brain damage and even death.

Thoracic surgery, video-assisted (VATS) is a minimally invasive surgical technique used to diagnose and treat various conditions related to the chest cavity, including the lungs, pleura, mediastinum, esophagus, and diaphragm. In VATS, a thoracoscope, a type of endoscope with a camera and light source, is inserted through small incisions in the chest wall to provide visualization of the internal structures. The surgeon then uses specialized instruments to perform the necessary surgical procedures, such as biopsies, lung resections, or esophageal repairs. Compared to traditional open thoracic surgery, VATS typically results in less postoperative pain, shorter hospital stays, and quicker recoveries for patients.

The solitary nucleus, also known as the nucleus solitarius, is a collection of neurons located in the medulla oblongata region of the brainstem. It plays a crucial role in the processing and integration of sensory information, particularly taste and visceral afferent fibers from internal organs. The solitary nucleus receives inputs from various cranial nerves, including the glossopharyngeal (cranial nerve IX) and vagus nerves (cranial nerve X), and is involved in reflex responses related to swallowing, vomiting, and cardiovascular regulation.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Synovial sarcoma is a rare type of cancer that typically develops in the soft tissues surrounding the joints, such as the synovial membrane, which lines the joint capsules. Despite its name, synovial sarcoma does not necessarily arise from the synovium. It is called so due to its resemblance to this tissue under a microscope.

This form of sarcoma primarily affects young adults and can be found in various parts of the body, but it most commonly occurs in the extremities, particularly near the knees. Synovial sarcoma is characterized by specific genetic changes that result in the formation of fusion proteins, which contribute to uncontrolled cell growth and tumor development.

There are two main subtypes of synovial sarcoma: monophasic and biphasic. Monophasic synovial sarcoma is composed of either spindle-shaped (spaghetti-like) cells or epithelioid (roundish) cells, while biphasic synovial sarcoma contains both types of cells. A third subtype, called poorly differentiated synovial sarcoma, has a more aggressive behavior and is composed of small round cells that do not resemble the typical spindle or epithelioid cells.

Treatment for synovial sarcoma usually involves surgical removal of the tumor, often followed by radiation therapy and/or chemotherapy to reduce the risk of recurrence and metastasis. The prognosis varies depending on factors such as the size and location of the tumor, the patient's age, and the presence of metastases at diagnosis.

Mesothelioma is a rare and aggressive form of cancer that develops in the mesothelial cells, which are the thin layers of tissue that cover many of the internal organs. The most common site for mesothelioma to occur is in the pleura, the membrane that surrounds the lungs. This type is called pleural mesothelioma. Other types include peritoneal mesothelioma (which occurs in the lining of the abdominal cavity) and pericardial mesothelioma (which occurs in the lining around the heart).

Mesothelioma is almost always caused by exposure to asbestos, a group of naturally occurring minerals that were widely used in construction, insulation, and other industries because of their heat resistance and insulating properties. When asbestos fibers are inhaled or ingested, they can become lodged in the mesothelium, leading to inflammation, scarring, and eventually cancerous changes in the cells.

The symptoms of mesothelioma can take many years to develop after exposure to asbestos, and they may include chest pain, coughing, shortness of breath, fatigue, and weight loss. Treatment options for mesothelioma depend on the stage and location of the cancer, but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Unfortunately, the prognosis for mesothelioma is often poor, with a median survival time of around 12-18 months after diagnosis.

Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.

Murray Valley Encephalitis Virus (MVEV) is a type of arbovirus (arthropod-borne virus) that is primarily transmitted to humans through the bite of an infected mosquito. The virus is named after the Murray Valley region in Australia where it was first identified.

MVEV is the causative agent of Murray Valley encephalitis, a serious illness that can affect the brain and cause inflammation (encephalitis). The virus is found primarily in Australia, Papua New Guinea, and parts of Southeast Asia.

The transmission cycle of MVEV involves mosquitoes serving as vectors that transmit the virus between birds and mammals, including humans. Infection with MVEV can cause a range of symptoms, from mild fever and headache to severe neurological complications such as seizures, coma, and permanent brain damage. There is no specific treatment for Murray Valley encephalitis, and prevention efforts focus on reducing mosquito populations and avoiding mosquito bites in areas where the virus is known to be present.

... (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura ... evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. H&E stain. Solitary fibrous tumor - ... "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor ... Giant solitary fibrous tumor of the pleura.] Cir Cir 2010;78:31-43. [Article in Spanish]. Tai, HC., Chuang, IC., Chen, TC. et ...
Gellman H. "Solitary Fibrous Tumor". Medscape. Retrieved 2 November 2011. Hammes HP, Lin J, Renner O, Shani M, Lundqvist A, ... Diagnosis of this tumor is difficult because of the inability to distinguish pericytes from other types of cells using light ... They may either be present in excess, leading to diseases such as hypertension and tumor formation, or in deficiency, leading ... Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O (December 2013). "Type-1 pericytes participate in fibrous tissue ...
... is a more aggressive tumor than dermatofibrosarcoma protuberans tumors). Solitary fibrous tumour, also fibrous termed tumor of ... Malignant FMTs Solitary fibrous tumor, malignant type, a malignant form of the solitary fibrous tumors Fibrosarcoma NOS, i.e. ... Zhang J, Liu J, Zhang Z, Tian B (2021). "Solitary Fibrous Tumors of the Chest: An Analysis of Fifty Patients". Frontiers in ... Martin-Broto J, Mondaza-Hernandez JL, Moura DS, Hindi N (June 2021). "A Comprehensive Review on Solitary Fibrous Tumor: New ...
Actual rates of hypoglycemia associated with a fibrous tumor are quite rare (a 1981 study of 360 solitary fibrous tumors of the ... Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P (July 2006). "Solitary fibrous tumor of the pleura ... Briselli M, Mark EJ, Dickersin GR (June 1981). "Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases ... Roy M, Burns MV, Overly DJ, Curd BT (November 1992). "Solitary fibrous tumor of the pleura with hypoglycemia: the Doege-Potter ...
"Orbital solitary fibrous tumor with multinucleate giant cells: case report of an unusual finding in an uncommon tumor". Indian ... Ali MJ, Honavar SG, Naik MN, Vemuganti GK (2011). "Orbital solitary fibrous tumor: A clinicopathologic correlation and review ... "Orbital solitary fibrous tumor: A rare clinicopathologic correlation and review of literature". J Res Med Sci. 18 (6): 529-31. ... Honavar SG, Manjandavida FP (2017). "Recent Advances in Orbital Tumors--A Review of Publications from 2014-2016". Asia Pac J ...
... and its tumor cells' loss of the RB1 gene. Solitary fibrous tumors differ from AFST tumors in their common location in the ... in its tumor cells. Among benign tumors, cellular angiofibroma and solitary fibrous tumor may be confused with AFST. Cellular ... AFST tumors are typically treated by total surgical resection in order to remove all tumor tissue. Uncommonly, these tumors ... AFTS tumors may also be confused with three malignant tumors, low-grade fibromyxoid sarcoma, myxofibrosarcoma, and myxoid ...
Pleural tumors may be benign (i.e. solitary fibrous tumor) or malignant in nature. Pleural mesothelioma is a type of malignant ... Pleural synovial sarcoma Pleural solitary fibrous tumor (pleural SFT, can be benign or less commonly malignant) Smooth muscle ... Mesothelial tumors: pleural malignant mesothelioma. Pleural sarcomas Pleural angiosarcoma Pleural desmoplastic small round cell ... "Pleural Tumors - Health Encyclopedia - University of Rochester Medical Center". www.urmc.rochester.edu. URMC. Retrieved 22 July ...
... is a diagnostic immunochemical marker for solitary fibrous tumour (SFT), distinguishing it from most mimics. Among other ... "GRIA2 is a Novel Diagnostic Marker for Solitary Fibrous Tumour Identified through Gene Expression Profiling". Histopathology. ... Cancer Decreased editing at the Q/R site is also found in some human brain tumors. Reduction of ADAR2 expression is thought to ...
Dong SS, Wang N, Yang CP, Zhang GC, Liang WH, Zhao J, Qi Y (2020). "Giant Cell-Rich Solitary Fibrous Tumor in the Nasopharynx: ... Furthermore, following their surgical resection GCF tumors may recur as DFSP tumors and vice versa and DFSP tumors may recur as ... DFSP tumors located in sites where these tumors are surgical inoperable primary tumors or locally inoperable recurrent tumors ... tumors. The World Health Organization (2020) classified these three tumors as different tumors in the category of fibroblastic ...
"Giant Cell-Rich Solitary Fibrous Tumor in the Nasopharynx: Case Report and Literature Review". OncoTargets and Therapy. 13: ... Giant cell tumors include giant-cell tumor of bone, giant-cell tumor of the tendon sheath, and giant cell fibroblastoma. ... Medicine portal Anaplastic large-cell lymphoma Buttock cell Massive giant-cell tumor of pelviacetabulum Nosology Giant+Cell+ ... Tumors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Dong SS, Wang N, Yang CP, Zhang GC, Liang WH, ...
Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P (Jul 2006). "Solitary fibrous tumor of the pleura ... IGF-2 is sometimes produced in excess in islet cell tumors and non-islet hypoglycemic cell tumors, causing hypoglycemia. Doege- ... is a paraneoplastic syndrome in which hypoglycemia is associated with the presence of one or more non-islet fibrous tumors in ... Loss of imprinting of IGF-2 is a common feature in tumors seen in Beckwith-Wiedemann syndrome. As IGF-2 promotes development of ...
September 2021). "Intracranial solitary fibrous tumor/hemangiopericytoma: tumor reclassification and assessment of treatment ... Tumor cells can be fibroblastic, myxoid, or pericytic. These tumors, in contrast to meningiomas, do not stain with epithelial ... When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with a special aggressive ... Hemangiopericytomas are tumors that are derived from specialized spindle shaped cells called pericytes, which line capillaries ...
Rekhi B, Bapat P, Shetty O (2019). "A Rare Case of a Vaginal Solitary Fibrous Tumor, Presenting as a Cystic Mass, Showing ... Vaginal tumors are neoplasms (tumors) found in the vagina. They can be benign or malignant. A neoplasm is an abnormal growth of ... Tumor is also not synonymous with cancer. While cancer is by definition malignant, a tumor can be benign, precancerous, or ... Some benign tumors may later progress to become malignant tumors, such as vaginal cancers. Some neoplastic growths of the ...
The fibromas are firm, smooth, and fibrous with a color usually identical to the oral mucosa but can be paler. If wounded, it ... They are usually solitary and do not develop into oral cancer. The epidermis of irritation fibromas typically exhibits ... Irritation fibromas are common benign tumors that are asymptomatic and resemble scarring. They are caused by prolonged ... "Oral cavity & oropharynx - Soft tissue tumors & proliferations - Irritation fibroma". pathology Outlines. Topic Completed: 26 ...
... have been identified in solitary fibrous tumors. GRCh38: Ensembl release 89: ENSG00000166886 - Ensembl, May 2017 GRCm38: ...
... have been identified in solitary fibrous tumors. Amplification STAT6 is amplified in a subset of dedifferentiated liposarcoma. ... Binnemars‐Postma, Karin; Bansal, Ruchi; Storm, Gert; Prakash, Jai (February 2018). "Targeting the Stat6 pathway in tumor‐ ... associated macrophages reduces tumor growth and metastatic niche formation in breast cancer". The FASEB Journal. 32 (2): 969- ... a region implicated in multiple solid tumors". Genomics. 52 (2): 192-200. doi:10.1006/geno.1998.5436. PMID 9782085. Zhu M, John ...
... solitary, deep fibrous nodule, often adherent to tendon, fascia, or periosteum, on the hands and feet. The World Health ... in 2020 reclassified aponeurotic fibroma nodules as a specific benign type of the fibroblastic and myofibroblastic tumors. Skin ...
Sweden Solitary fibrous tumor, a rare mesenchymal tumor Statens forurensningstilsyn or Norwegian Climate and Pollution Agency ...
... glomus tumor, metanephric adenoma, epithelioid angiomyolipoma, Wilms tumor, solitary fibrous tumor, and some epithelial ... Juxtaglomerular cell tumor (JCT, JGCT, also reninoma) is an extremely rare kidney tumour of the juxtaglomerular cells, with ... In most cases the tumor is encapsulated. Juxtaglomerular cell tumor was first described in 1967 in a paper by Robertson et al ... This tumor typically secretes renin, hence the former name of reninoma. It often causes severe hypertension that is difficult ...
... fibrosarcomatous Giant cell fibroblastoma Malignant solitary fibrous tumor Inflammatory myofibroblastic tumor Low-grade ... larger tumors tend to have a worse prognosis compared to smaller tumors. Spread of tumor to surrounding tissues: tumors that ... Tumor grade: higher grade tumors (grades 2 and 3) tend to have a worse prognosis compared to low grade (grade 1) tumors. ... Leiomyosarcoma Malignant peripheral nerve sheath tumor Rhabdomyosarcoma Synovial sarcoma Malignant solitary fibrous tumor. ...
... solitary fibrous tumors, and various sarcomas. Two new[when?] eribulin based products are in the research and development phase ... These non-mitotic mechanisms include vascular remodeling that leads to increased tumor perfusion and mitigation of tumor ... Eribulin is being investigated for use in a variety of other solid tumors, including breast cancer, non-small cell lung cancer ... Clinical trial number NCT03207672 for "Study of E7389 Liposomal Formulation in Subjects With Solid Tumor" at ClinicalTrials.gov ...
... meningioma 7.1 Soft tissue tumours 7.1.1 Fibroblastic and myofibroblastic tumours 7.1.1.1 Solitary fibrous tumour 7.1.2 ... tumor 1.5.6 Rosette-forming glioneuronal tumor 1.5.7 Myxoid glioneuronal tumor 1.5.8 Diffuse leptomeningeal glioneuronal tumor ... 3 malignant tumour and /1 borderline tumour), and the WHO Grade (a parameter connected with the "aggressiveness" of the tumour ... Grading of the tumors of the central nervous system See the article Grading of the tumors of the central nervous system. Louis ...
Fibrosarcomas arise from the fibrous tissues just beneath the skin. They may be present as solitary, irregular masses on the ... Skin tumors manifest as a visible lump on the skin, mostly affecting vision, smell, or eating. Benign tumors take several years ... Melanomas are not common in cats but when they are, they manifest as basal cell tumors. These tumors are benign in nature, but ... It asserts that the tumor would have been eliminated if the tumor microenvironment had not been suppressive. Rather than ...
Individuals with solitary tumors are usually treated by observation with the expectation that many of these tumors will regress ... It is nonetheless the most common tumor derived from fibrous connective tissue that occurs primarily in infants and young ... IMF tumors occur in three clinical patterns: 1) solitary IMF tumors (also called myofibromas) which often regress spontaneously ... Single tumors located in vital areas (e.g. intracranial tumors) and tumors that do not regress over suitable observation ...
Most cases presented as solitary masses but 3 cases presenting with 2 tumors and 1 case presenting with 5 tumors. Overall, the ... Fibrous hamartoma of infancy (FHI) is a rare, typically painless, benign tumor that develops in the subcutaneous tissues of the ... Fibrous hamartoma of infancy is generally a benign tumor but may be locally aggressive, locally infiltration, and in uncommon ... The tumor was first described by R.D. Reye in 1956 who termed the disorder "subdermal fibromatous tumor of infancy" and ...
However, these tumors have the potential to grow reaching a remarkable size, particularly in young individuals. The tumor is ... Clinically, fibroadenomas are usually solid breast lumps that are: Painless Firm or rubbery Mobile Solitary-round with distinct ... fibrous and fatty tissues. Fibroadenomas develop from the lobules. The glandular tissue and ducts grow over the lobule to form ... In the male breast, fibroepithelial tumors are very rare, and are mostly phyllodes tumors. Exceptionally rare case reports ...
... solitary tumors commonly occurring in the head and neck regions; multiple tumors occurring in the skin, subcutaneous tissue, ... Pachydermodactyly Knuckle pads Dermatofibroma Nodular fasciitis Elastofibroma Fibrous papule of the face Aggressive ... It is classed by the World Health Organization as an intermediate soft tissue tumor related to the sarcoma family. Arthur Purdy ... The term fibromatosis refers to a group of soft tissue tumors which have certain characteristics in common, including absence ...
... solitary fibrous tumor, and other conditions. Such conditions may therefore also be incorrectly diagnosed as desmoid tumors (29 ... Desmoid tumor D48.110: Desmoid tumor of head and neck D48.111: Desmoid tumor of chest wall D48.112: Desmoid tumor, ... Desmoid Tumor Research Foundation (Booklet). The Desmoid Tumor Working Group. 2020. "About Desmoid Tumors". Desmoid Tumor ... Desmoid tumor, intraabdominal Desmoid tumor of pelvic cavity Desmoid tumor, peritoneal, retroperitoneal D48.115: Desmoid tumor ...
... s are hard solitary slow-growing papules (rounded bumps) that appear in a variety of colours, usually brownish to ... A dermatofibroma, or benign fibrous histiocytomas, is a benign nodule in the skin, typically on the legs, elbows or chest of an ... Dermal and subcutaneous tumors". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 617- ... Other bumps such as granular cell tumor, melanoma, clear cell acanthoma and dermatofibrosis lenticularis disseminata may look ...
... solitary, asymptomatic acral nodules, characterized histologically by well-circumscribed subcutaneous tumors composed of smooth ... A sclerotic lipoma is a predominantly fibrous lesion with focal areas of fat. Neural fibrolipomas are overgrowths of fibro- ... They are the most common noncancerous soft-tissue tumor. The first use of the term "lipoma" to describe these tumors was in ... These tumors can occur at any age, but are most common in middle age, often appearing in people from 40 to 60 years old. ...
Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura ... evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. H&E stain. Solitary fibrous tumor - ... "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor ... Giant solitary fibrous tumor of the pleura.] Cir Cir 2010;78:31-43. [Article in Spanish]. Tai, HC., Chuang, IC., Chen, TC. et ...
... is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. SFT used to be called localized ... is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. SFT used to be called localized ... Solitary fibrous tumor (SFT) is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. SFT ... Benign lung tumors. In: Broaddus VC, Ernst JD, King Jr TE, et al, eds. Murray and Nadels Textbook of Respiratory Medicine. 7th ...
... of all soft-tissue tumors and was more of a characteristic histopathologic pattern t... ... encoded search term (Solitary Fibrous Tumor) and Solitary Fibrous Tumor What to Read Next on Medscape ... The Value of MRI and Clinical Features in Differentiating Between Cellular and Fibrous Solitary Fibrous Tumors. AJR Am J ... Solitary fibrous tumor in the extremity: case report and review of the literature. Clin Orthop Relat Res. 2003 Jun. 236-44. [ ...
Solitary fibrous tumors are mostly noncancerous overgrowth arising from the mesenchymal tissue. The mesenchyme is the middle ... Solitary fibrous tumors of the soft tissue may cause hypoglycemia.. Solitary fibrous tumors in the pleura can cause chest pain ... Known side effects of solitary fibrous tumors. One of the known side effects of solitary fibrous tumors is a slow-growing ... Treatments, management plans for solitary fibrous tumors. Treatment for solitary fibrous tumors often involves a surgical ...
Discover a fascinating case report of a 65-year-old womans chest wall tumor resection. Uncover the unique histological ... Histologically, the tumor was diagnosed as a cellular variant of solitary fibrous tumor of the pleura, with branching "staghorn ... Y. Zhu, K. Du, X. Ye, D. Song and D. Long, "Solitary Fibrous Tumors of Pleura and Lung: Report of Twelve Cases," Journal of ... X. Chu, L. Zhang, Z. Xue, et al., "Solitary Fibrous Tumor of the Pleura: An Analysis of Forty Patients," Journal of Thoracic ...
Core Tip: The clinical manifestations of orbital solitary fibrous tumor (SFT) are diverse and not specific. In most cases, the ... Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital ... Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital. ... Ming-Yu Ren, Yi-Xiang Wu, Rui-Miao Li, Li-Min Liu, Jing-Jing Wang, Yu Gao, Department of Orbital Disease and Ocular Tumor, ...
Lipomatous Hemangiopericytoma [Fat Forming Variant of Solitary Fibrous Tumour] - A Rare Variant of Hemangiopericytoma That Can ...
Solitary fibrous tumors are typically indolent tumors of the pleura.•Primary origin in the female reproductive organs is rare, ... "Solitary fibrous tumor of the vulva resulting in spinal metastasis: A case report." Gynecol Oncol Rep, vol. 22, Nov. 2017, pp. ... "Solitary fibrous tumor of the vulva resulting in spinal metastasis: A case report." Gynecol Oncol Rep 22 (November 2017): 97-99 ... Solitary fibrous tumor of the vulva resulting in spinal metastasis: A case report.. Publication , Journal Article ...
A) Malignant solitary fibrous tumor. A 2 kilogram pleural solitary fibrous tumor in a 36-year-old female. The collagenous area ... A) Malignant solitary fibrous tumor. A 2 kilogram pleural solitary fibrous tumor in a 36-year-old female. The collagenous area ... Malignant solitary fibrous tumor. SFTs are large round to lobulated well-circumscribed tumors that range in size from 1-40 cm ... Immunohistochemical comparison of gastrointestinal stromal tumor and solitary fibrous tumor. Arch Pathol Lab Med. 2002. 126: ...
... of all soft-tissue tumors and was more of a characteristic histopathologic pattern t... ... encoded search term (Solitary Fibrous Tumor) and Solitary Fibrous Tumor What to Read Next on Medscape ... Solitary fibrous tumor in the extremity: case report and review of the literature. Clin Orthop Relat Res. 2003 Jun. 236-44. [ ... The term solitary fibrous tumor (SFT) is favored by soft-tissue pathologists to describe a rare, heterogeneous group of benign ...
We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). The diagnosis was ... Keywords: Solitary fibrous; Orbit tumor; Mesenchymal origin tumor; CD34. Download PDF Introduction. Solitary fibrous tumour ( ... 2011) Orbital solitary fibrous tumor: encompassing terminology for hemangiopericytoma, giant cell angiofibroma, and fibrous ... Renshaw AA (1995) O13 (CD99) in spindle cell tumors. Reactivity with hemangiopericytoma, solitary fibrous tumor, synovial ...
Solitary fibrous tumor causing cardiac tamponade.. Tamenishi A, Matsumura Y, Okamoto H. Ann Thorac Surg 2013 Jul;96(1):319-21. ... Giant intrapericardial solitary fibrous tumor.. Bortolotti U, Calabrò F, Loy M, Fasoli G, Altavilla G, Marchese D. Ann Thorac ... Primary cardiac solitary fibrous tumors.. Taguchi S. Ann Thorac Cardiovasc Surg 2015;21(4):329-31. Epub 2015 Jul 7 doi: 10.5761 ... Intraorbital metastasis from solitary fibrous tumor.. Patel MM, Jakobiec FA, Zakka FR, Du R, Annino DJ, Borboli-Gerogiannis S, ...
Diagnosis: Malignant solitary fibrous tumor Week 203: Case 6. Diagnosis: Malignant solitary fibrous tumor Week 46: Case 5. ... Search by Diagnosis: "Malignant solitary fibrous tumor". Show Diagnoses. Week 271: Case 2. ...
A Case Report of Rare Sacral Solitary Fibrous Tumor ... Huge primary epidural solitary fibrous tumors in the sacrum are ... Solitary fibrous tumor (SFT), also previously known as hemangiopericytoma, is a rare mesenchymal neoplasm of fibroblastic ... July 31, 2022) A Case Report of Rare Sacral Solitary Fibrous Tumor. Cureus 14(7): e27524. doi:10.7759/cureus.27524 ... For more info please read, A Case Report of Rare Sacral Solitary Fibrous Tumor, by Cureus ...
In the current report we present three cases of solitary fibrous tumors of the orbital area that we have seen in a relatively ... are currently recognized as solitary fibrous tumors, and probably hemangiopericytomas, solitary fibrous tumors, giant cell ... Orbital Solitary Fibrous Tumor: Report of a Three Cases Series. Vilardell F1*, Huerva V2, Abó A1, Sánchez MC2 and Matias-Guiu X ... Keywords: Solitary fibrous Tumour; Orbit area; Hemangiopericytoid; CD34; CD99. Subscription required. Please login to access ...
Solitary fibrous tumor (SFT) is a neoplasm typically arising in the pleura. Yet, extrapleural cases have been described and are ... Solitary fibrous tumor is a rare mesenchymal tumor of the urinary bladder, but should always be considered in the differential ... Solitary fibrous tumor of the urinary bladder: report of a case with long-term follow-up and review of the literature ... Solitary fibrous tumor of the urinary bladder: report of a case with long-term follow-up and review of the literature. V. ...
keywords = "Doubling time, Dynamic CT, Gd-EOB-DTPA-enhanced MRI, Liver tumor, Solitary fibrous tumor", ... Solitary fibrous tumor of the liver from development to resection. In: Internal Medicine. 2015 ; Vol. 54, No. 7. pp. 765-770. ... Solitary fibrous tumor of the liver from development to resection. Internal Medicine. 2015 Apr 1;54(7):765-770. doi: 10.2169/ ... title = "Solitary fibrous tumor of the liver from development to resection",. abstract = "A 55-year-old man was annually ...
Join us for Abdominal Cases for Aces e very Tuesday at 11am PST / 2 pm EST ! Zoom ID 210-616-481 - Direct message us on Twitter for the p ...
Keywords : pleuropulmonary solitary fibrous tumor, solitary fibrous tumor of the pleura, surgical resection, stratification ... A rare cause of chest pain: pleuropulmonary solitary fibrous tumor Raúl Gonzalez Luna1,Gerardo Rea Mendoza1,Christian Ramirez ... The postoperative pathology of the patient was reported as a pleuropulmonary solitary fibrous tumor. The management of this ... At the chest tomography, a low-density mass with the presence of multiple vascularized septa, without evidence of tumor ...
Solitary fibrous tumor of the seminal vesicle. Goyal, Shikha; Madan, Renu; Mukherjee, Urmi; More ... Solitary osteochondroma of the rib: An unusual chest wall tumor in the pediatric age group. Tiwari, Charu; Borkar, Nitinkumar; ...
... non-islet cell tumor hypoglycemia,solitary fibrous tumor,thoracotomy,tumor-induced hypoglycemia ... Keywords : Hypoglycemia, non-islet cell tumor hypoglycemia, solitary fibrous tumor, thoracotomy, tumor-induced hypoglycemia ... Late-Onset Non-islet Cell Tumor Hypoglycemia Associated with a Pleural Solitary Fibrous Tumor ... Late-Onset Non-islet Cell Tumor Hypoglycemia Associated with a Pleural Solitary Fibrous Tumor. ...
"Solitary fibrous tumor of the thyroid: Cytopathologic findings and differential diagnosis",. abstract = "Solitary fibrous tumor ... Parwani, A. V., Galindo, R., Steinberg, D. M., Zeiger, M. A., Westra, W. H., & Ali, S. Z. (2003). Solitary fibrous tumor of the ... Solitary fibrous tumor of the thyroid: Cytopathologic findings and differential diagnosis. Anil V. Parwani, Rene Galindo, David ... Solitary fibrous tumor of the thyroid: Cytopathologic findings and differential diagnosis. Diagnostic cytopathology. 2003 Apr 1 ...
"Concurrent hepatic hemangioma and solitary fibrous tumor: diagnosis and management",. abstract = "Hepatic solitary fibrous ... Hepatic solitary fibrous tumor (HSFT) is a very rare benign liver tumor without well-defined findings on imaging. Even with ... N2 - Hepatic solitary fibrous tumor (HSFT) is a very rare benign liver tumor without well-defined findings on imaging. Even ... AB - Hepatic solitary fibrous tumor (HSFT) is a very rare benign liver tumor without well-defined findings on imaging. Even ...
Solitary Fibrous Tumor: An Uncommon Cause of Paraparesis and Sciatic Pain ... Solitary fibrous tumor (SFT) is a rare type of soft tissue neoplasia, usually seen in adults. They are mesenchymal neoplasias ... Long-term follow-up of these patients is required because of the risk of recurrence of these tumors and their uncertain ...
... and CD34 expression with development of malignant solitary fibrous tumour we have studied 10 cases of solitary fibrous tumour ... and CD34 expression with development of malignant solitary fibrous tumour we have studied 10 cases of solitary fibrous tumour ... and CD34 expression with development of malignant solitary fibrous tumour we have studied 10 cases of solitary fibrous tumour ... and CD34 expression with development of malignant solitary fibrous tumour we have studied 10 cases of solitary fibrous tumour ...
Classification of Tumors of the Pleura has recently been published. While the histologic classification of pleural malignant ... Another useful discovery was that the NAB2-STAT6 fusion is characteristic of solitary fibrous tumors. This led to development ... Solitary fibrous tumor; WWTR1-CAMTA1; p16; β-catenin. ... reliable immunohistochemical marker for solitary fibrous tumors ... The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification J Thorac ...
... is the extensive surgical resection that is curative for most benign lesions.We present the case of solitary fibrous tumor of ... Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have ... Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have ... Anterior mediastinal solitary fibrous tumor resection by da Vinci® Surgical System in obese patient.. Ontology highlight ...
Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. ... Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. ...
Giant Solitary Fibrous Tumor of the mesentery- A rare case. 2011-01-09 Kudva R Monappa V Rao A Journal of Cancer Research and ... Multifocal fibrous dysplasia with enchondroma like areas ( Fibrocarti-laginous dysplasia ). 2008-01-01 Monappa V Kudva R ... Pure Testicular Teratomapresenting as a Metastatic germ cell Tumour. 2014-01-03 Kudva R Kudva A IJSRP Vol.4, Issue 3, March ... Sclerosing stromal tumour of the ovary. 2000-01-01 The Journal of Obstetrics and Gynaecology of India, 2000, 50 (4)127-28. ...
A biphasic tumor consisting of pilocytic astrocytoma with an anaplastic solitary fibrous tumor component in the pineal region: ... A biphasic tumor consisting of pilocytic astrocytoma with an anaplastic solitary fibrous tumor component in the pineal region: ... A biphasic tumor consisting of pilocytic astrocytoma with an anaplastic solitary fibrous tumor component in the pineal region: ... T1 - A biphasic tumor consisting of pilocytic astrocytoma with an anaplastic solitary fibrous tumor component in the pineal ...
  • Solitary fibrous tumor (SFT), also known as fibrous tumor of the pleura, is a rare mesenchymal tumor originating in the pleura or at virtually any site in the soft tissue including seminal vesicle. (wikipedia.org)
  • Robinson LA. Solitary fibrous tumor of the pleura. (wikipedia.org)
  • Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases in the literature" Cancer 1981;47:2678-89. (wikipedia.org)
  • Solitary fibrous tumor (SFT) is a noncancerous tumor of the lining of the lung and chest cavity, an area called the pleura. (medlineplus.gov)
  • However, these tumors are commonly found in the pleura, which is the area in the lining of the lung and chest cavity. (naturalpedia.com)
  • In rare cases, solitary fibrous tumors of soft tissue may cause hypoglycemia, while the side effects of solitary fibrous tumors in the pleura include chest pain, a persistent cough, and shortness of breath. (naturalpedia.com)
  • Solitary fibrous tumors in the pleura can cause chest pain, a persistent cough, and shortness of breath. (naturalpedia.com)
  • Histologically, the tumor was diagnosed as a cellular variant of solitary fibrous tumor of the pleura, with branching "staghorn" vessels and hypervascularity. (scirp.org)
  • Solitary Fibrous Tumor of the Pleura: An Analysis of Forty Patients," Journal of Thoracic Diseases, Vol. 4, No. 2, 2012, pp. 146-154. (scirp.org)
  • Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome. (nih.gov)
  • Solitary fibrous tumor (SFT) is a neoplasm typically arising in the pleura. (europeanreview.org)
  • Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm that arises primarily from the pleura. (johnshopkins.edu)
  • Aims: To clarify the association of p53 and CD34 expression with development of malignant solitary fibrous tumour we have studied 10 cases of solitary fibrous tumour arising in the pleura, retroperitoneum and pelvic cavity with clinicopathological features of malignancy. (fujita-hu.ac.jp)
  • A new World Health Organization (WHO) Classification of Tumors of the Pleura has recently been published. (nih.gov)
  • Finally, desmoid type fibromatosis, a locally aggressive tumor that can present in the pleura, has been shown to frequently have CTNNB1 gene mutations and express β-catenin by immunohistochemistry. (nih.gov)
  • Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have been described at many extra pleural sites, such as mediastinum. (omicsdi.org)
  • Neoplasia poco frecuente, generalmente benigna, derivada de los fibroblastos mesenquimatosos localizados en la zona submesotelial de la PLEURA. (bvsalud.org)
  • SFTs are tumors of mesenchymal origin. (medscape.com)
  • Solitary fibrous tumors are mostly noncancerous overgrowth arising from the mesenchymal tissue. (naturalpedia.com)
  • SFTs are malignant tumors of mesenchymal origin that occur in the extremities. (medscape.com)
  • Solitary fibrous tumor (SFT), also previously known as hemangiopericytoma, is a rare mesenchymal neoplasm of fibroblastic origin, accounting for less than 2% of all soft tissue tumors [1] . (axisneuromonitoring.com)
  • Solitary fibrous tumor is a rare mesenchymal tumor of the urinary bladder, but should always be considered in the differential diagnosis of spindle cell neoplasms encountered in the lower genital tract. (europeanreview.org)
  • We describe areas where major inroads were initially achieved by targeting angiogenesis and by unraveling pathways in the heterogeneous tumors of mesenchymal origin-spurred by the identification of c-Kit-activating mutations in GIST and the regressions that ensued when tumors harboring these mutations were exposed to the tyrosine kinase inhibitor imatinib (Gleevec). (cancernetwork.com)
  • Here, in Part I, we describe areas where major inroads were initially achieved by targeting angiogenesis (central to the biology of renal cell carcinoma and hepatocellular cancer) and by unraveling pathways in the heterogeneous tumors of mesenchymal origin-spurred by the identification of c-Kit-activating mutations in gastrointestinal stromal tumors (GIST) and the regressions that ensued when tumors harboring these mutations were exposed to the tyrosine kinase inhibitor imatinib (Gleevec). (cancernetwork.com)
  • BACKGROUND: Solitary fibrous tumours (SFT) are mesenchymal neoplasias rarely found in the orbit. (uzh.ch)
  • Hemangiopericytoma Myopericytoma Gross pathology of an atypical solitary fibrous tumor, evidenced by some deeply yellow necrotic areas Solitary fibrous tumor - low magnification. (wikipedia.org)
  • The tumor thus resembled a chest wall hemangiopericytoma. (scirp.org)
  • Penel N, Amela EY, Decanter G, Robin YM, Marec-Berard P. Solitary fibrous tumors and so-called hemangiopericytoma. (medscape.com)
  • Fat forming solitary fibrous tumor, previously known as lipomatous hemangiopericytoma, is a rare variant of solitary fibrous tumor (SFT) ( Korean J Pathol 2014;48:69 ). (pathologyoutlines.com)
  • Another group of tumors once thought to arise from cells around blood vessels, hemangiopericytoma, is now termed solitary fibrous tumor/hemangiopericytoma, since the tumors all appear to be very similar in terms of their biology. (sarctrials.org)
  • Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry. (biocare.net)
  • However, over time, the staghorn-branching vascular pattern representative of HPC was found to be present at least focally in 15% of all soft-tissue tumors and was more of a characteristic histopathologic pattern than a specific clinicopathologic entity. (medscape.com)
  • [ 8 ] The 2020 WHO classification of soft-tissue tumors listed SFT as an intermediate (rarely metastasizing) tumor. (medscape.com)
  • Soft-tissue SFTs represent only about 1-2% of all soft-tissue tumors. (medscape.com)
  • citation needed] Over the years pleural SFTs acquired a number of synonyms, including localized fibrous tumor, benign mesothelioma, localized fibrous mesothelioma, submesothelial fibroma, and pleural fibroma. (wikipedia.org)
  • SFT used to be called localized fibrous mesothelioma. (medlineplus.gov)
  • Ren MY, Li J, Wu YX, Li RM, Zhang C, Liu LM, Wang JJ, Gao Y. Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital. (wjgnet.com)
  • Vilardell F, Huerva V, Abó A, Sánchez MC, Matias-Guiu X (2014) Orbital Solitary Fibrous Tumor: Report of a Three Cases Series. (scitechnol.com)
  • Solitary fibrous tumor (SFT) was first described in 1870 by Wagner and further established in 1931 by Klemperer and Rabin as a pleural neoplasm. (medscape.com)
  • Solitary fibrous tumour (SFT) is an uncommon neoplasm at the orbital level that behaves in benign way in most cases [ 1 ]. (scitechnol.com)
  • Prognosis of this neoplasm is obscure and long-term follow-up is required for all cases of solitary fibrous tumor. (europeanreview.org)
  • Due to this change, tumor grades more accurately reflect the cellular behavior and subsequent clinical course of each neoplasm. (medscape.com)
  • While the terminology implies a benign neoplasm, most if not all fibromas represent reactive focal fibrous hyperplasia due to trauma or local irritation. (medscape.com)
  • It is an uncommon benign fibrous neoplasm that occurs most commonly in the skin and may be solitary or multifocal. (medscape.com)
  • In the current report we present three cases of solitary fibrous tumors of the orbital area that we have seen in a relatively short lapse of time. (scitechnol.com)
  • 1,2) Nuclear expression of STAT6 is found in nearly all cases of solitary fibrous tumor (SFT) and is very limited in other soft tissue neoplasms making it a highly sensitive and specific immunohistochemical marker for SFT and may help to distinguish this tumor type from histologic mimics. (biocare.net)
  • High-resolution computed tomography scan of the thorax showed a 19.5 cm × 16.6 cm × 23.8 cm mass in the left hemithorax, and a microscopic examination of a biopsy specimen of which was consistent with the diagnosis of solitary fibrous tumor. (endocrinolrespract.org)
  • Post-operatively, histopatho- logical diagnosis of solitary fibrous tumor was confirmed. (endocrinolrespract.org)
  • Although CD34 is a useful marker in the diagnosis of solitary fibrous tumour, one should bear in mind that its expression can be lost in high-grade tumours. (fujita-hu.ac.jp)
  • On one end, a fibrous form is characterized by hyalinized, thick-walled vessels with opened lumina and strong CD34 reactivity. (medscape.com)
  • Immunohistochemical studies showed CD34 positivity in seven, but three of them showed marked diminution or complete loss of CD34 expression in high-grade loci or a recurrent tumour. (fujita-hu.ac.jp)
  • The tumor cells are CD34 and vimentin positive. (medscape.com)
  • The treatment of choice for both benign and malignant SFT is complete en bloc surgical resection. (wikipedia.org)
  • We present a case report of a 65-year-old woman who underwent resection of a chest wall tumor. (scirp.org)
  • It is diagnosed using immunohistochemical technique and the treatment of choice is surgical resection of the tumour in order to prevent recurrences. (scitechnol.com)
  • Usually, local resection of the tumour is sufficient. (scitechnol.com)
  • However, in some situations, infiltration of the tumour requires more extensive resection of adjacent tissues. (scitechnol.com)
  • As far as possible, treatment involves complete resection as the presence of remnants of intraorbital tumour tissue after the operation carries the risk of causing recurrence of the tumour and can even undergo transformation by becoming malignant [ 3 ]. (scitechnol.com)
  • Anterior mediastinal solitary fibrous tumor resection by da Vinci® Surgical System in obese patient. (omicsdi.org)
  • The treatment of choice is the extensive surgical resection that is curative for most benign lesions.We present the case of solitary fibrous tumor of the anterior mediastinum in obese patient (BMI: 34.3) undergoing complete surgical resection by robotic-assisted thoracoscopic surgery with da Vinci® Surgical System.Robotic-assisted thoracoscopic surgery with da Vinci® Surgical System is an interesting option for obese patient, at higher risk for deep sternal wound infection. (omicsdi.org)
  • To achieve negative resection margins, the width of the tumor-free margins and infiltrating depth are two essential factors to be considered for complete excision for both WLE and MMS surgical techniques. (thieme-connect.de)
  • A right nephrectomy with resection of the mass demonstrated a malignant solitary fibrous tumor. (medscape.com)
  • Definitive management of hypoglycemia associated with paraneoplastic production of IGF-2 consists of resection of the tumor responsible for IGF-2 production. (medscape.com)
  • ABSTRACT: Nerve sheath myxomas (NEUROTHEKEOMA) are uncommon tumors of nerve sheet origin. (scirp.org)
  • When hypoglycemia does occur in such individuals, an uncommon but important diagnosis to consider is non-islet cell tumor hypoglycemia (NICTH). (medscape.com)
  • Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)
  • The fibroma, also referred to as irritation fibroma, is by far the most common of the oral fibrous tumorlike growths. (medscape.com)
  • The clinical differential diagnosis of a fibroma depends on its clinical presentation and location and includes giant cell fibroma, neurofibroma , peripheral giant cell granuloma , schwannoma, granular cell tumor, mucocele , and benign and malignant salivary gland tumors (eg, see Salivary Gland Neoplasms ). (medscape.com)
  • Histologically, a fibroma is an unencapsulated, solid, nodular mass of dense and sometimes hyalinized fibrous connective tissue that is often arranged in haphazard fascicles. (medscape.com)
  • Giant cell fibroma is the oral counterpart of fibrous papule of the nose . (medscape.com)
  • The term solitary fibrous tumor (SFT) is favored by soft-tissue pathologists to describe a rare, heterogeneous group of benign and malignant neoplasms along a morphologic continuum. (medscape.com)
  • Therefore, the TNM (Tumor size, Nodal involvement, Metastases) system used for most non-CNS tumors is not commonly employed in the evaluation of CNS neoplasms. (medscape.com)
  • Because neoplasms in the CNS have widely varying features, clinical courses, and prognoses, a robust and reliable grading system is essential for the proper evaluation of CNS tumors. (medscape.com)
  • abstract = "Here we report a case of a biphasic tumor consisting of pilocytic astrocytoma with anaplastic solitary fibrous tumor component in the pineal region. (elsevierpure.com)
  • Because the identification of key histopathologic features is highly sensitive to sampling, the new guidelines recommend using molecular signatures-which tend to be more diffuse and thus less sensitive to sampling-as a component in grading certain tumors and as a potential marker of clinical course and prognosis. (medscape.com)
  • Hepatic solitary fibrous tumor (HSFT) is a very rare benign liver tumor without well-defined findings on imaging. (utmb.edu)
  • These tumors have a high risk of recurring where they start and can also travel to liver, bone, lung, and other sites. (sarctrials.org)
  • The tumor can travel not only elsewhere in the abdominal or pelvic cavity where it starts, but it can also spread to liver, lung, or the space between the lungs (mediastinum). (sarctrials.org)
  • The majority of the tumor showed typical histologic features of pilocytic astrocytoma. (elsevierpure.com)
  • Sarcomatoid renal cell carcinoma (SRCC) is currently defined in the 2004 World Health Organization (WHO) classification of renal tumors as any histologic type of renal cell carcinoma (RCC) containing foci of high-grade malignant spindle cells. (medscape.com)
  • In cases in which the histologic subtype of the RCC component is not recognizable, the tumor is designated as unclassified RCC with sarcomatoid differentiation. (medscape.com)
  • [ 13 , 14 ] MRT usually arises in children younger than 3 years, and the occasional cases previously reported as adult MRT are now considered more likely to be RRCC in which rhabdoid components have overgrown the original histologic tumor type. (medscape.com)
  • Currently, the 2004 WHO classification of renal tumors recognizes this transformation as "sarcomatoid change" or "sarcomatoid features" arising within RCC, rather than as a separate histologic entity. (medscape.com)
  • [ 3 ] Consequently, grading each tumor requires an integrated analysis of histologic features and molecular signatures specific to that tumor type. (medscape.com)
  • Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. (biocare.net)
  • Conclusions: Malignant solitary fibrous tumours may occur de novo or by transformation within benign or low-grade tumours and may be associated with p53 mutation. (fujita-hu.ac.jp)
  • Recurrent somatic fusions of the two genes, NGFI-A-binding protein 2 (NAB2) and STAT6, located at chromosomal region 12q13, have been identified in solitary fibrous tumors. (wikipedia.org)
  • NAB2-STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors. (wikipedia.org)
  • The clinicopathological significance of NAB2-STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors. (nih.gov)
  • Another useful discovery was that the NAB2-STAT6 fusion is characteristic of solitary fibrous tumors. (nih.gov)
  • This led to development of a STAT6 antibody that is a reliable immunohistochemical marker for solitary fibrous tumors. (nih.gov)
  • Recently, STAT6 has received considerable attention in the area of tumor growth and metastasis. (biocare.net)
  • Scholars@Duke publication: Solitary fibrous tumor of the vulva resulting in spinal metastasis: A case report. (duke.edu)
  • We report a case of a vulvar solitary fibrous tumor, notable for extensive spinal metastasis. (duke.edu)
  • Intraorbital metastasis from solitary fibrous tumor. (nih.gov)
  • proposed the risk assessment score for predicting the development of metastasis in SFTs, which included the patient age, tumor size, mitotic activity, and the presence of necrosis. (axisneuromonitoring.com)
  • DSRCT is composed of small cells with round hyperchromatic nuclei and a dense fibrous or spindle cell stroma. (medscape.com)
  • A minor part of the tumor showed marked proliferation of short spindle cells around vessels. (elsevierpure.com)
  • Histopathology demonstrated well-circumscribed tumor (2 × 1 × 1 cm) as spindle-shaped subepithelial cells hyperplasia, in a "whorled" focal arrangement around collagen stroma and made a storiform structure, with monomorphic nuclei and eosinophilic cytoplasm. (thieme-connect.de)
  • If benign tumors are not removed, they have the potential to become cancerous. (naturalpedia.com)
  • Approximately 63% of patients will have a recurrence of their tumor, of which more than half will succumb to disease progression within two years. (wikipedia.org)
  • Long-term follow-up of these patients is required because of the risk of recurrence of these tumors and their uncertain biological behavior. (journalmc.org)
  • Radiation is occasionally used to try and prevent tumor recurrence, and chemotherapy is largely ineffective for this diagnosis. (sarctrials.org)
  • 1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
  • Surgery and radiation of the primary tumor site provide the best chance for cure. (sarctrials.org)
  • Solitary fibrous tumors of the soft tissue may cause hypoglycemia. (naturalpedia.com)
  • Maldar AN, Chauhan PH, Lala M, Deshpande R. Late-onset non-islet cell tumor hypoglycemia associated with a pleural solitary fibrous tumor. (endocrinolrespract.org)
  • Solitary fibrous tumor associated with hypoglycemia: an example of the Doege-Potter syndrome. (ox.ac.uk)
  • Review of recent reported cases of NICTH identified widespread anatomic locations and varied pathologic diagnoses of tumors associated with paraneoplastic production of IGF-2 causing hypoglycemia. (medscape.com)
  • Some tumors contain only mature adipose tissue, whereas others contain multivacuolated lipoblasts and may have areas resembling atypical lipomatous tumor (ALT) ( Am J Surg Pathol 2011;35:1177 ). (pathologyoutlines.com)
  • Most periocular tumors formerly identified as soft tissue hemangiopericytomas, are currently recognized as solitary fibrous tumors, and probably hemangiopericytomas, solitary fibrous tumors, giant cell angiofibromas and fibrous histiocytomas are actually the same tumour, despite some morphologic and immuno labeling variations. (scitechnol.com)
  • RR CC was named for its morphologic resemblance to pediatric malignant rhabdoid tumor (MRT) of the kidney, which is a highly aggressive tumor characterized by cells that resemble rhabdomyoblasts and by genetic alterations involving chromosome 22, particularly the hSNF5/INI1 gene on 22q11.2. (medscape.com)
  • On cut sections, the tumors are tan-white and rubbery and have admixed, soft, yellow lipid rich foci ( Arch Pathol Lab Med 1999;123:941 , Am J Surg Pathol 1995;19:748 ). (pathologyoutlines.com)
  • Mature fat varies in amount but usually occupies approximately one quarter to three quarters of the area of tumor ( Am J Surg Pathol 1999;23:1201 ). (pathologyoutlines.com)
  • While some researchers have proposed that a SFT occupying at least 40% of the affected hemithorax be considered a "giant solitary fibrous tumor", no such "giant" variant has yet been recognized within the most widely used pleural tumor classification scheme. (wikipedia.org)
  • As such, CNS tumor classification heavily relies on accurate grading , which reflects the degree of abnormal behavior displayed by the tumor cells themselves. (medscape.com)
  • In 1979, the World Health Organization (WHO) codified its first set of guidelines on the classification and staging of CNS tumors. (medscape.com)
  • As an example, consider the classification of anaplastic tumors as elaborated in the WHO guidelines and Louis et al. (medscape.com)
  • Published in 2021, the fifth edition of the WHO Classification of Tumors of the CNS is the most recent version of the international standard for classifying brain and spinal cord tumors. (medscape.com)
  • Table 2 delineates the possible grades for each specific tumor type described in the 2021 WHO Classification of CNS Tumors. (medscape.com)
  • We present two clinical cases of patients aged 36 and 74 with an orbital solitary fibrous tumour (SFT). (scitechnol.com)
  • Huge primary epidural solitary fibrous tumors in the sacrum are a rare clinical entity. (axisneuromonitoring.com)
  • Giant pancreatic tumor with clinical characteristics of insulinoma but without common pathologic features. (rochester.edu)
  • [ 2 ] Grade was applied across tumor types, regardless of differences in the clinical course and molecular behavior of different anaplastic tumor entities. (medscape.com)
  • Although the term focal fibrous hyperplasia more accurately describes the clinical appearance and pathogenesis of this entity, it is not commonly used. (medscape.com)
  • Neurilemmomas arising from Schwann cells, rarely found in oral cavity, are characterized by solitary occurrence, slow growth and smooth surface with variable clinical aspects, depending on the nerve origin. (bvsalud.org)
  • At the chest tomography, a low-density mass with the presence of multiple vascularized septa, without evidence of tumor extension, without mediastinum nodes growth, neither metastatic lesions. (tgcd.org.tr)
  • These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
  • Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
  • Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
  • To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
  • Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. (allenpress.com)
  • Some SFTs are associated with the paraneoplastic Doege-Potter syndrome, which is caused by tumor production of IGF-2. (wikipedia.org)
  • SFTs have also been known as hemangiopericytomas although this term has now been discontinued from WHO tumor classifications. (wikipedia.org)
  • [ 11 ] SFTs were initially incorrectly considered to be a localized form of fibrous mesothelioma. (medscape.com)
  • The postoperative pathology of the patient was reported as a pleuropulmonary solitary fibrous tumor. (tgcd.org.tr)
  • I discuss issues pertaining to the practice of neuropathology -- including nervous system tumors, neuroanatomy, neurodegenerative disease, muscle and nerve disorders, ophthalmologic pathology, neuro trivia, neuropathology gossip, job listings and anything else that might be of interest to a blue-collar neuropathologist. (blogspot.com)
  • These rare tumors can develop in any part of the body. (naturalpedia.com)
  • Other parts of the body where these rare tumors can form include the spinal cord, dura, head and neck, arms and legs, abdominal parenchymal organs, retroperitoneum, peritoneum, and pelvic organs. (naturalpedia.com)
  • It is one of the rare tumors with features of both sarcoma and melanoma, including the ability to travel to lymph nodes (typical of melanoma) and to lung (more common for sarcomas). (sarctrials.org)
  • Why and how it is replacing past approaches in the management of solid tumors is the subject of this two-part overview. (cancernetwork.com)
  • The situation with solid tumors is considerably more complex, and the evolution of targeted therapies for these cancers is still in its infancy. (cancernetwork.com)
  • At present, and for some years to come, the treatment of most solid tumors will continue to rely on a patchwork of empirically derived and newly introduced molecularly targeted agents. (cancernetwork.com)
  • The use of names that include mesothelioma for this tumor is discouraged because of potential confusion with diffuse malignant mesothelioma, a much more serious disease. (wikipedia.org)
  • A single-center study by DeVito et al found that malignant SFT, as compared with benign SFT, was associated with larger tumors, elevated mitotic counts, the presence of metastases at diagnosis, and more extensive use of chemotherapy and RT. (medscape.com)
  • Giant solitary fibrous tumor of the diaphragm: a case report and review of literature. (nih.gov)
  • Giant intrapericardial solitary fibrous tumor. (nih.gov)
  • Initial differentials involved more common masses in the sacral area, such as chordoma, chondrosarcoma, and giant cell tumor. (axisneuromonitoring.com)
  • The World Health Organization (2020) classified SFT as a specific type of tumor in the category of malignant fibroblastic and myofibroblastic tumors. (wikipedia.org)
  • This tumor typically spreads via hematogenous dissemination, primarily to the lungs, but rarely spreads via the lymphatics. (medscape.com)
  • This tumor typically arises in the skin and must be excised by an appropriate expert, as less extensive resections often end in failure. (sarctrials.org)
  • Sarcoma is a rare type of cancer and typically produces malignant tumors derived from the connective tissue. (curesarcoma.org)
  • Solitary fibrous tumors were previously known as localized fibrous mesotheliomas. (naturalpedia.com)
  • [ 7 ] Tumors with pure sarcomatoid morphology due to overgrowth of the RCC components are classified as SRCC if evidence of epithelial differentiation can be demonstrated through immunohistochemical or ultrastructural analysis. (medscape.com)
  • For example, the term epulis fissuratum refers to epithelial and fibrous hyperplasia specifically related to, and the result of, trauma from the border of a removable denture. (medscape.com)
  • This type of tumor affects men and women equally. (medlineplus.gov)
  • About one half of the people with this type of tumor do not show any symptoms. (medlineplus.gov)
  • Many of these sarcomas have some (but not all) features in common with their bone-tumor equivalents, and each has unique characteristics that must be considered in their treatment. (sarctrials.org)
  • 4 mitoses/10 high-power fields [HPF]) lesions characterized by cytologic atypia, tumor necrosis, or infiltrative margins. (medscape.com)