Torovirus Infections

Torovirus

Mamastrovirus

Cattle Diseases

CORONAVIRIDAE4

• The information from immunofluorescence studies and morphology of the bovine Toroviruses (BToV) intestinal cells has shown similarities among the EToVs and BToVs.Torovirus share some common characteristics with members of the related family Coronaviridae as they are round, pleomorphic, enveloped viruses about 120 to 140 nm in diameter. (wikipedia.org)
• Infections with viruses of the genus TOROVIRUS , family CORONAVIRIDAE . (nih.gov)
• Infecciones producidas por virus del género TOROVIRUS, familia CORONAVIRIDAE. (bvsalud.org)
• The replication-transcription complex includes enzyme functions commonly found in positive-strand RNA viruses, like an RNAdependent RNA polymerase (nsp12 [13]), proteases (nsp3 and The family Coronaviridae, comprising the genera Coronavirus and Torovirus, belongs to the order Nidovirales, a lineage of positive-strand RNA viruses that also includes the Arteriviridae and Roniviridae families (for a review, see reference 28). (dadospdf.com)

Punta Toro Virus2

• Punta Toro virus (Bunyaviridae, Phlebovirus) infection in mice: strain" by M Mendenhall, M H. Wong et al. (usu.edu)
• 10. TLR3 is essential for the induction of protective immunity against Punta Toro Virus infection by the double-stranded RNA (dsRNA), poly(I:C12U), but not Poly(I:C): differential recognition of synthetic dsRNA molecules. (nih.gov)

Positive-strand RNA viruses1

• Torovirus is a genus of enveloped, positive-strand RNA viruses in the order Nidovirales and family Tobaniviridae. (wikipedia.org)

Viruses3

• Toroviruses (ToV) are single-stranded RNA viruses that have a peplomer-bearing envelope that is often correlated with the enteric infections in cattle and possibly humans. (wikipedia.org)
• These viruses, primarily transmitted by mosquitoes and ticks, are responsible for hundreds of millions of human infections worldwide each year. (nih.gov)
• Antibiotics have no effect on viruses, but antiviral drugs have been developed to treat life-threatening infections. (wikidoc.org)

Genus1

• Torovirus is the only genus in the monotypic subfamily Torovirinae. (wikipedia.org)

Diseases1

• Our goal is to develop new strategies and antimicrobial therapies to eliminate infection diseases. (csic.es)

Viral infections3

• The ability of these complexes to elicit protective immunity against viral infections has not been fully explored. (usu.edu)
• Viral infections in human and animal hosts usually result in an immune response and disease . (wikidoc.org)
• Vaccines that produce lifelong immunity can prevent viral infections. (wikidoc.org)

Immunity1

• Protective Immunity against Acute Phleboviral Infection Elicited throu" by Brian B. Gowen, J. Fairman et al. (usu.edu)

Gastroenteritis2

• In 1984, torovirus-like particles were detected with electron microscope (EM) technique in the human patients with gastroenteritis. (wikipedia.org)
• Control measures for outbreaks of viral gastroenteritis should focus on the removal of an ongoing common source of infection (e.g., an ill food handler or the contamination of a water supply) and on the interruption of person-to-person transmission that can perpetuate an outbreak in a population after the common source has been removed. (cdc.gov)

Specimens1

• Many diagnostic techniques for torovirus infection in clinical specimens are now available such as hemagglutination (HA), enzyme-linked immunosorbent assay (ELISA), immune electron microscopy, hemagglutination-inhibition tests (HA/HI), and nucleic acid hybridization. (wikipedia.org)

Pathogens3

• This interactive and multidisciplinary environment provides to my laboratory a means to open new areas to study new mechanisms of bacterial infections and to discover new antimicrobial strategies to fight antibiotic resistance and multi-drug resistance pathogens, with special emphasis on those associated with hospital infections. (csic.es)
• Airborne pathogens present a unique challenge in infectious disease and infection control, for a small percentage of infectious individuals appear to be responsible for disseminating the majority of infectious particles. (datexis.com)
• Building on the basics of aerobiology, we then explore the common origins of droplet and airborne infections, as these are factors critical to understanding the epidemiology of diverse airborne pathogens. (datexis.com)

Species3

• Distribution of confirmed Punta Toro species complex infections, Panama, 2009. (nih.gov)
• Among various species of the Toroviruses, only equine torovirus (EToV) can be grown in the cell culture medium due to which EToVs have been most extensively studied. (wikipedia.org)
• The clinical significance of some species in causing animal infections to include allergic (hypersensitivity) pneumonitis. (stemcelldaily.com)

Humans2

• Mostly torovirus infecting humans are probably closely related to BRV or BEV and relate to any previous history of some enteric disease or infection. (wikipedia.org)
• They can also cause allergic reactions, respiratory infections, skin infections, eye infections, and systemic infections in animals and humans. (stemcelldaily.com)

Hemorrhagic3

• Infections by pathogenic New World mammarenaviruses (NWM)s, including Junín virus (JUNV), can result in a severe life-threatening viral hemorrhagic fever syndrome. (bvsalud.org)
• Our findings support the continued development of ARN-75039 as an attractive therapeutic candidate for treating mammarenaviral hemorrhagic fevers, including those associated with NWM infection. (bvsalud.org)
• African swine fever virus (ASFV) infections in Africa cause hemorrhagic disease in domestic pigs and is maintained by a sylvatic cycle in warthogs. (biomedcentral.com)

Calves1

• 2016). It has been found that in beef calves, BCoV infection was more frequent among calves up to 30 days of age (Quinn et al. (ac.ir)

Inhibits2

• 7. Activation of Toll-like receptors inhibits herpes simplex virus-1 infection of human neuronal cells. (nih.gov)
• Here, we demonstrate that an antibody (ch128.1/IgG1) which binds the apical domain of hTfR1, potently inhibits infection of attenuated and pathogenic NWMs in vitro. (bvsalud.org)

Typically1

• Torovirus particles typically possess a helical and symmetrical nucleocapsid that is coiled into a hollow cylindrical shape. (wikipedia.org)

Diarrhea2

• Equine torovirus (EToV) was accidentally found in the rectal sample from a horse who was experiencing severe diarrhea. (wikipedia.org)
• It can occur in conjunction with gastrointestinal disease, especially tapeworms and possibly other GI parasites, and has been linked to a torovirus by some researchers (Papasouliotis 1996) due to finding this virus in cats with chronic diarrhea and elevation of the third eyelids. (vetinfo.com)

Herpes1

• Chlamydiosis and herpes virus infection are sometimes associated with bilateral elevation of the third eyelids but they usually have obvious ocular signs associated with them, as well. (vetinfo.com)

Common2

• Infection with FCoV is very common in cats and kittens. (dadospdf.com)
• Common infection on cruise ships. (wikidoc.org)

Mice1

• ARN-75039 is a potent fusion inhibitor of a broad spectrum of pseudotyped and native mammarenaviruses in cell culture and Tacaribe virus infection in mice. (bvsalud.org)

Virus1

• [10] Dimitri Ivanovski used this filter to study an infection of tobacco plants, now known as tobacco mosaic virus . (wikidoc.org)

Structural2

• The Torovirus genome encodes for various structural proteins like spikes (S), membrane proteins (M), haemagglutinin‐esterase (HE) and nucleocapsid (N) which provides them the structural characterization necessary for infection and completing their life cycle. (wikipedia.org)
• To do this, we work in the interface of molecular and cellular biology with other scientific disciplines, such as structural, infection, synthetic and systems biology. (csic.es)

Study1

• In the present study, we evaluated ARN-75039 against pathogenic JUNV in the rigorous guinea pig infection model. (bvsalud.org)

Human1

• NIAID preclinical services have capabilities for testing candidates in a wide range of viral infection models in rodents and non-human primates (NHP). (nih.gov)

Animal1

• NIAID can engage contractors to develop and standardize reproducible animal infection models. (nih.gov)

Include1

• There are some principles to decrease the risk of acquiring infection which include, using safe water and foods, avoid unsafe foods during traveling and hand washing. (wikidoc.org)

Found2

• The 'Breda' bovine torovirus was later found in 1979 while investigation in a dairy farm in Breda. (wikipedia.org)
• Genome length of porcine Torovirus was found to be 28301 bp and possess 79% sequence identity with the bovine Torovirus genome. (wikipedia.org)

Produce1

• Microorganisms may produce toxins that facilitate infection. (medscape.com)

Factors3

• In addition to the ingestion of pathogenic organisms or toxins, other intrinsic factors can lead to infection. (medscape.com)
• Potential risk factors for herd-level Salmonella infection were identified. (avma.org)
• however, no other factors were associated with Salmonella infection after adjustment for herd size. (avma.org)

Model1

• My laboratory is a key laboratory in the field of functional membrane microdomain bacterial compartmentalization and its role during infections, using MRSA (Methicillin-resistance Staphylococcus aureus ) as model organisms. (csic.es)