III Delta1-Pyrroline-5-carboxylic acid dehydrogenase". J. Biol. Chem. 235: 3218-3223. Portal: Biology (Articles with short ... L-pyrroline-5-carboxylate-NAD+ oxidoreductase, and 1-pyrroline-5-carboxylate:NAD+ oxidoreductase. This enzyme participates in ... In enzymology, a 1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) is an enzyme that catalyzes the chemical reaction (S)-1- ... pyrroline-5-carboxylate + NAD+ + 2 H2O ⇌ {\displaystyle \rightleftharpoons } L-glutamate + NADH + H+ The three substrates of ...
Protein target information for 1-pyrroline-5-carboxylate dehydrogenase (Geobacillus sp. WCH70). Find diseases associated with ...
The ALDH4A1 gene provides instructions for producing the enzyme pyrroline-5-carboxylate dehydrogenase, which is found in ... Pyrroline-5-carboxylate dehydrogenase starts the second step in the process that breaks down the protein building block (amino ... Yoshida A, Rzhetsky A, Hsu LC, Chang C. Human aldehyde dehydrogenase gene family. Eur J Biochem. 1998 Feb 1;251(3):549-57. doi ... A lack of pyrroline-5-carboxylate dehydrogenase function leads to decreased breakdown of proline and elevated levels of proline ...
6. Probable proline dehydrogenase 2. General function:. Involved in proline dehydrogenase activity. Specific function:. ... These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group ( ... Pyrroline-5-carboxylate is highly reactive and excess quantities have been shown to cause cell death and apoptosis (PMID: ... Under certain conditions, pyrroline-5-carboxylate can act as a neurotoxin and a metabotoxin. A neurotoxin causes damage to ...
... dehydrogenase), showed milder illness or no symptoms at all. Next, state-of-the-art 2-photon intravital microscopy (IVM) was ... Notably, mice infected with fungal cells unable to catabolize proline, e.g., cells lacking the Put2 enzyme (1-pyrroline-5- ... carboxylate (P5C) ...
... pyrroline-5-carboxylate is converted into 4-hydroxyglutamate and (R)- 1-pyrroline-5-carboxylate is converted into D-glutamate. ... S)-1-pyrroline-5-carboxylate, the product of the first enzyme of the pathway (EC 1.5.5.2) is in spontaneous equilibrium with ... All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-. All ENZYME / UniProtKB/Swiss-Prot entries corresponding to ... The enzyme can also oxidize other 1-pyrrolines, e.g. 3-hydroxy-1- ...
3A). Glutamate degradation occurs through the reaction catalyzed by glutamate dehydrogenase (RocG) and glutamate synthetase ( ... 5. Effect of exogenous addition of glutamate and proline on a growth-dependent butanol tolerance of B. subtilis 168. Cells were ... 1. Butanol tolerance of B. subtilis 168. Cells were inoculated in LB medium and exposed to butanol at various concentrations ( ... Additional file 1. One-dimensional SDS-PAGE for protein separation of B. subtilis 168 with and without butanol treatment. ...
Pyrroline Carboxylate Reductases [D08.811.682.662.695] Pyrroline Carboxylate Reductases * Saccharopine Dehydrogenases [D08.811. ... Dehydrogenase, GGS Dehydrogenase, Glutamic-Gamma-Semialdehyde Dehydrogenase, Glutamyl-Gamma-Semialdehyde Delta(1)-Pyrroline-5- ... Carboxylate Dehydrogenase GGS Dehydrogenase Glutamic Gamma Semialdehyde Dehydrogenase Glutamic-Gamma-Semialdehyde Dehydrogenase ... Dehydrogenase, GGS. Dehydrogenase, Glutamic-Gamma-Semialdehyde. Dehydrogenase, Glutamyl-Gamma-Semialdehyde. Delta(1)-Pyrroline- ...
Pyrroline Carboxylate Reductases 9% * Metabolome 9% * Lipids 9% * Biomarkers 9% * Thiazolidines 9% ... Uridine Diphosphate Glucose Dehydrogenase 7% * In Vitro Techniques 7% * X-Rays 7% ...
citronellyl-CoA dehydrogenase activity GO:0034824 * positive regulation by symbiont of defense-related host calcium ion flux ...
malate dehydrogenase (menaquinone) activity GO:0052589 * tumor necrosis factor-activated receptor activity ...
L-threonate 3-dehydrogenase activity GO:0050036 * negative regulation of lipoprotein lipase activity ...
L-alanine dehydrogenase (RefSeq). 90, 256. BSU33540. yvaB. azoreductase (RefSeq). 90, 353. ... POSITION A C G T 1 0.9 0.0 0.1 0.0 2 0.05 0.3 0.65 0.0 3 0.0 0.15 0.85 0.0 4 0.95 0.0 0.05 0.0 5 0.05 0.0 0.95 0.0 6 0.45 0.05 ... 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this ... 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this ...
Delta-1-pyrroline-5-carboxylate dehydrogenase deficiency From NCATS Genetic and Rare Diseases Information Center ...
AZOBR_RS32620: aldehyde dehydrogenase. is similar to:. PaperBLAST. putA / GB,BAA35791.1: proline dehydrogenase/delta-1- ... pyrroline-5-carboxylate dehydrogenase; EC 1.5.1.12; EC 1.5.99.8 from Escherichia coli ... AZOBR_RS29750: aldehyde dehydrogenase. is similar to:. PaperBLAST. putA / GB,BAA35791.1: proline dehydrogenase/delta-1- ... AZOBR_RS31000: aldehyde dehydrogenase. is similar to:. PaperBLAST. putA / GB,BAA35791.1: proline dehydrogenase/delta-1- ...
aldehyde dehydrogenase 4 (glutamate gamma-semialdehyde dehydrogenase;. pyrroline-5-carboxylate dehydrogenase) * P5C ... aldehyde dehydrogenase 4 (glutamate gamma-semialdehyde dehydrogenase; pyrroline-5-carboxylate dehydrogenase). * converting ... aldehyde dehydrogenase family. CATEGORY enzyme , transport SUBCELLULAR LOCALIZATION intracellular intracellular,cytoplasm, ... 10 Kb 5 upstream gene genomic sequence study MAPPING cloned Y linked N status confirmed RNA. ...
Ortholog function: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) Oceanobacillus iheyensis HTE831 OB1349 -29. 4.2 ... Ortholog function: Acetyltransferase, GNAT family (EC 2.3.1.-) Anoxybacillus flavithermus WK1 Aflv_0223 -64. 4.6. ...
Gene: RBAM_034980: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12). Gene: RBAM_003450: Delta-1-pyrroline-5- ... carboxylate dehydrogenase (EC 1.5.1.12) Bacillus pumilus SAFR-032 Gene: BPUM_0301: Delta-1-pyrroline-5-carboxylate ... Gene: GK0187: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12). Gene: GK2889: Delta-1-pyrroline-5-carboxylate ... Gene: Aflv_0249: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) ...
6-phosphogluconate dehydrogenase [3] (data from MRSA252). SAOUHSC_01633. glycine dehydrogenase subunit 1 [3] (data from MRSA252 ... glyceraldehyde 3-phosphate dehydrogenase 2 [3] (data from MRSA252). SAOUHSC_01801. isocitrate dehydrogenase [3] (data from ... pyruvate dehydrogenase complex, E1 component subunit alpha [3] (data from MRSA252). SAOUHSC_01041. pyruvate dehydrogenase ... 2-oxoglutarate dehydrogenase E1 component [3] (data from MRSA252). SAOUHSC_01216. (sucC). succinyl-CoA synthetase subunit beta ...
DEHYDROGENASE, NAD+, OXIDOREDUCTASE 4fgw:B (LYS81) to (SER149) STRUCTURE OF GLYCEROL-3-PHOSPHATE DEHYDROGENASE, GPD1, FROM ... DEHYDROGENASE 1o95:C (PRO66) to (VAL145) TERNARY COMPLEX BETWEEN TRIMETHYLAMINE DEHYDROGENASE AND ELECTRON TRANSFERRING ... COLI PYRUVATE DEHYDROGENASE E1 COMPONENT E401K MUTANT WITH THIAMIN DIPHOSPHATE , PYRUVATE DEHYDROGENASE, THIAMIN DIPHOSPHATE, ... STRUCTURE OF SALMONELLA D-LACTATE DEHYDROGENASE , OXIDOREDUCTASE, D-2-HYDROXYACID DEHYDROGENASES, LDH, PYRUVATE 3oc0:B (TRP563 ...
This enzyme begins the process of degrading proline by starting the reaction that converts it to pyrroline-5-carboxylate.[ ... 2-Methylbutyryl-CoA dehydrogenase deficiency. *Beta-ketothiolase deficiency. *Maple syrup urine disease ... This enzyme helps to break down the pyrroline-5-carboxylate produced in the previous reaction, converting it to the amino acid ... A deficiency of either proline oxidase or pyrroline-5-carboxylate dehydrogenase results in a buildup of proline in the body. A ...
Keywords: Aldehyde dehydrogenase; Alcoholic liver disease; Diacylglycerol lipase; Endocannabinoids; Homocysteine INTRODUCTION. ... where glutamate is converted to pyrroline-5-carboxylate (P5C) through P5C synthase and further metabolized into proline or ... Interestingly, P5C is conversely converted to glutamate by aldehyde dehydrogenase 4 family member A1 (ALDH4A1) [27]. ... which is further metabolized by acetaldehyde dehydrogenase to acetate in the mitochondria of hepatocytes [3]. In chronic ...
Pyruvate dehydrogenase E1 component subunit β (PdhB). P99063. 1.84 ↓. 2.23 ↓. 12. Dihydrolipoyl dehydrogenase (PdhD). P99084. ... Glyceraldehyde-3-phosphate dehydrogenase 1 (GapA1). P99136. 1.62 ↓. * the arrow denotes the direction of regulation; ↑ up- and ... Glyceraldehyde-3-phosphate dehydrogenase 1 (GapA1). P99136. 1.5 ↓. 16. 3-hexulose-6-phosphate synthase (HPS). Q7A774. 1.92 ↓. ... Pyruvate dehydrogenase E1 component subunit β (PdhB). P99063. 2.19 ↓. 1.82 ↓. 2. Succinate--CoA ligase (ADP-forming) subunit α ...
Some of the immunodominant antigens include charge variants of EF-Tu, glyceraldehyde-3-phosphate dehydrogenase, ... pyruvate dehydrogenase complex, and others exist as charge variants on two-dimensional gels. These charge variants have similar ... and a dihydrolipoamide dehydrogenase. Alanine racemase and neutral protease were uniquely immunogenic to B. anthracis. ... 5. Identification of human T cell leukemia virus type 1 tax amino acid signals and cellular factors involved in secretion of ...
... malate dehydrogenase and lactate dehydrogenase. Applied Microbiology and Biotechnology 40(5): 676-681 ... Baker, P.J.; Sha, J.A.; Mcbride, M.W. 1999: Expression of 3b-hydroxysteroid dehydrogenase type I and type VI isoforms in the ... Davie, J.R.; Wynn, R.Max; Meng, M. 1995: Expression and characterization of branched-chain a-ketoacid dehydrogenase kinase from ... Seong, H.H.; Shiota, K.; Noda, K. 1992: Expression of activities of two 20a-hydroxysteroid dehydrogenase isozymes in rat ...
carboxylate. dehydrogenase,. mitochondrial. Proline. dehydrogenase. 1,. mitochondrial. Pyrroline-5-. carboxylate. reductase 2. ... Pyrroline hydroxycarboxylic. acid. NAD. NADH. ATP. AMP. PP. i. Glycine. Ornithine. Dissipation. Guanidoacetic acid. S- ... 1-Pyrroline-2-carboxylic acid. NH. 3. H. 2. O. 2. H. 2. O. O. 2. 1-Pyrroline-4-hydroxy-2-. carboxylate. NH. 3. H. 2. O. 2. NAD ... 1-Pyrroline-5-carboxylic acid. NAD. H. 2. O. NADH. L-Proline. NAD. NADH. Oxoglutaric acid. O. 2. 4-Hydroxyproline. Succinic ...
carboxylate. dehydrogenase,. mitochondrial. Alanine. aminotransferase. 1. Glutamate. dehydrogenase. 1,. mitochondrial. ... pyrroline-5-. ... 5-carboxylic. acid. ATP. NH. 3. ADP. P. i. L-Glutamine. H. 2. O ... dehydrogenase,. mitochondrial. Glutamine--tRNA. ligase. L-Glutamic acid. Carbamoyl phosphate. 5-Phosphoribosylamine. γ- ... 5-phosphate. Magnesium. FAD. Pyridoxal. 5-phosphate. Pyridoxal. 5-phosphate. tRNA(Glu). L-Glutamyl-. tRNA(Glu). tRNA(Gln). L ...
carboxylate. dehydrogenase,. mitochondrial. Proline. dehydrogenase. 1,. mitochondrial. Pyrroline-5-. carboxylate. reductase 2. ... Pyrroline hydroxycarboxylic. acid. NAD. NADH. ATP. AMP. PP. i. Glycine. Ornithine. Guanidoacetic acid. S-Adenosylmethionine. S- ... 1-Pyrroline-2-carboxylic acid. NH. 3. H. 2. O. 2. H. 2. O. O. 2. 1-Pyrroline-4-hydroxy-2-. carboxylate. NH. 3. H. 2. O. 2. NAD ... 1-Pyrroline-5-carboxylic acid. NAD. H. 2. O. NADH. L-Proline. NAD. NADH. Oxoglutaric acid. O. 2. 4-Hydroxyproline. Succinic ...
BioCyc: META:L-DELTA1-PYRROLINE_5-CARBOXYLATE Provided by MetaNetX (CC BY 4.0) ...
Pyrroline Carboxylate Reductases [D08.811.682.662.695] * Saccharopine Dehydrogenases [D08.811.682.662.750] * Tetrahydrofolate ... Methylenetetrahydrofolate Dehydrogenase (NAD+) [D08.811.682.662.217] * Methylenetetrahydrofolate Dehydrogenase (NADP) [D08.811. ... Pyridoxine-5-Phosphate Oxidase Narrower Concept UI. M0018245. Registry Number. 0. Terms. Pyridoxine-5-Phosphate Oxidase ... Pyridoxine-5-Phosphate Oxidase Pyridoxinephosphate Oxidase Registry Number. EC 1.4.3.5. CAS Type 1 Name. Pyridoxamine 5- ...