1-Pyrroline-5-carboxylate dehydrogenase - Wikipedia
III Delta1-Pyrroline-5-carboxylic acid dehydrogenase". J. Biol. Chem. 235: 3218-3223. Portal: Biology (Articles with short ... L-pyrroline-5-carboxylate-NAD+ oxidoreductase, and 1-pyrroline-5-carboxylate:NAD+ oxidoreductase. This enzyme participates in ... In enzymology, a 1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) is an enzyme that catalyzes the chemical reaction (S)-1- ... pyrroline-5-carboxylate + NAD+ + 2 H2O ⇌ {\displaystyle \rightleftharpoons } L-glutamate + NADH + H+ The three substrates of ...
1-pyrroline-5-carboxylate dehydrogenase (Geobacillus sp. WCH70) | Protein Target - PubChem
ALDH4A1 gene: MedlinePlus Genetics
The ALDH4A1 gene provides instructions for producing the enzyme pyrroline-5-carboxylate dehydrogenase, which is found in ... Pyrroline-5-carboxylate dehydrogenase starts the second step in the process that breaks down the protein building block (amino ... Yoshida A, Rzhetsky A, Hsu LC, Chang C. Human aldehyde dehydrogenase gene family. Eur J Biochem. 1998 Feb 1;251(3):549-57. doi ... A lack of pyrroline-5-carboxylate dehydrogenase function leads to decreased breakdown of proline and elevated levels of proline ...
Human Metabolome Database: Showing metabocard for 1-Pyrroline-5-carboxylic acid (HMDB0001301)
6. Probable proline dehydrogenase 2. General function:. Involved in proline dehydrogenase activity. Specific function:. ... These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group ( ... Pyrroline-5-carboxylate is highly reactive and excess quantities have been shown to cause cell death and apoptosis (PMID: ... Under certain conditions, pyrroline-5-carboxylate can act as a neurotoxin and a metabotoxin. A neurotoxin causes damage to ...
Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence | ScienceDaily
... dehydrogenase), showed milder illness or no symptoms at all. Next, state-of-the-art 2-photon intravital microscopy (IVM) was ... Notably, mice infected with fungal cells unable to catabolize proline, e.g., cells lacking the Put2 enzyme (1-pyrroline-5- ... carboxylate (P5C) ...
ENZYME - 1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
... pyrroline-5-carboxylate is converted into 4-hydroxyglutamate and (R)- 1-pyrroline-5-carboxylate is converted into D-glutamate. ... S)-1-pyrroline-5-carboxylate, the product of the first enzyme of the pathway (EC 1.5.5.2) is in spontaneous equilibrium with ... All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-. All ENZYME / UniProtKB/Swiss-Prot entries corresponding to ... The enzyme can also oxidize other 1-pyrrolines, e.g. 3-hydroxy-1- ...
The significance of proline and glutamate on butanol chaotropic stress in Bacillus subtilis 168 | Biotechnology for Biofuels...
3A). Glutamate degradation occurs through the reaction catalyzed by glutamate dehydrogenase (RocG) and glutamate synthetase ( ... 5. Effect of exogenous addition of glutamate and proline on a growth-dependent butanol tolerance of B. subtilis 168. Cells were ... 1. Butanol tolerance of B. subtilis 168. Cells were inoculated in LB medium and exposed to butanol at various concentrations ( ... Additional file 1. One-dimensional SDS-PAGE for protein separation of B. subtilis 168 with and without butanol treatment. ...
DeCS
Pyrroline Carboxylate Reductases [D08.811.682.662.695] Pyrroline Carboxylate Reductases * Saccharopine Dehydrogenases [D08.811. ... Dehydrogenase, GGS Dehydrogenase, Glutamic-Gamma-Semialdehyde Dehydrogenase, Glutamyl-Gamma-Semialdehyde Delta(1)-Pyrroline-5- ... Carboxylate Dehydrogenase GGS Dehydrogenase Glutamic Gamma Semialdehyde Dehydrogenase Glutamic-Gamma-Semialdehyde Dehydrogenase ... Dehydrogenase, GGS. Dehydrogenase, Glutamic-Gamma-Semialdehyde. Dehydrogenase, Glutamyl-Gamma-Semialdehyde. Delta(1)-Pyrroline- ...
Redox Biology Center - Fingerprint - Research Nebraska
Bio2Vec
Bio2Vec
Bio2Vec
Network Portal - Gene BSU03480
L-alanine dehydrogenase (RefSeq). 90, 256. BSU33540. yvaB. azoreductase (RefSeq). 90, 353. ... POSITION A C G T 1 0.9 0.0 0.1 0.0 2 0.05 0.3 0.65 0.0 3 0.0 0.15 0.85 0.0 4 0.95 0.0 0.05 0.0 5 0.05 0.0 0.95 0.0 6 0.45 0.05 ... 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this ... 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this ...
Specific PHGKB|Rare Diseases PHGKB|PHGKB
Curated BLAST
AZOBR_RS32620: aldehyde dehydrogenase. is similar to:. PaperBLAST. putA / GB,BAA35791.1: proline dehydrogenase/delta-1- ... pyrroline-5-carboxylate dehydrogenase; EC 1.5.1.12; EC 1.5.99.8 from Escherichia coli ... AZOBR_RS29750: aldehyde dehydrogenase. is similar to:. PaperBLAST. putA / GB,BAA35791.1: proline dehydrogenase/delta-1- ... AZOBR_RS31000: aldehyde dehydrogenase. is similar to:. PaperBLAST. putA / GB,BAA35791.1: proline dehydrogenase/delta-1- ...
Genatlas sheet
aldehyde dehydrogenase 4 (glutamate gamma-semialdehyde dehydrogenase;. pyrroline-5-carboxylate dehydrogenase) * P5C ... aldehyde dehydrogenase 4 (glutamate gamma-semialdehyde dehydrogenase; pyrroline-5-carboxylate dehydrogenase). * converting ... aldehyde dehydrogenase family. CATEGORY enzyme , transport SUBCELLULAR LOCALIZATION intracellular intracellular,cytoplasm, ... 10 Kb 5 upstream gene genomic sequence study MAPPING cloned Y linked N status confirmed RNA. ...
Propagation of ArgR regulog to Bacillus thuringiensis serovar konkukian str. 97-27
ArgR: Bacillales
Gene: RBAM_034980: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12). Gene: RBAM_003450: Delta-1-pyrroline-5- ... carboxylate dehydrogenase (EC 1.5.1.12) Bacillus pumilus SAFR-032 Gene: BPUM_0301: Delta-1-pyrroline-5-carboxylate ... Gene: GK0187: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12). Gene: GK2889: Delta-1-pyrroline-5-carboxylate ... Gene: Aflv_0249: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) ...
SAOUHSC 02801 - AureoWiki
6-phosphogluconate dehydrogenase [3] (data from MRSA252). SAOUHSC_01633. glycine dehydrogenase subunit 1 [3] (data from MRSA252 ... glyceraldehyde 3-phosphate dehydrogenase 2 [3] (data from MRSA252). SAOUHSC_01801. isocitrate dehydrogenase [3] (data from ... pyruvate dehydrogenase complex, E1 component subunit alpha [3] (data from MRSA252). SAOUHSC_01041. pyruvate dehydrogenase ... 2-oxoglutarate dehydrogenase E1 component [3] (data from MRSA252). SAOUHSC_01216. (sucC). succinyl-CoA synthetase subunit beta ...
Protein Concepts Dictionary
DEHYDROGENASE, NAD+, OXIDOREDUCTASE 4fgw:B (LYS81) to (SER149) STRUCTURE OF GLYCEROL-3-PHOSPHATE DEHYDROGENASE, GPD1, FROM ... DEHYDROGENASE 1o95:C (PRO66) to (VAL145) TERNARY COMPLEX BETWEEN TRIMETHYLAMINE DEHYDROGENASE AND ELECTRON TRANSFERRING ... COLI PYRUVATE DEHYDROGENASE E1 COMPONENT E401K MUTANT WITH THIAMIN DIPHOSPHATE , PYRUVATE DEHYDROGENASE, THIAMIN DIPHOSPHATE, ... STRUCTURE OF SALMONELLA D-LACTATE DEHYDROGENASE , OXIDOREDUCTASE, D-2-HYDROXYACID DEHYDROGENASES, LDH, PYRUVATE 3oc0:B (TRP563 ...
Hyperprolinemia - WikiProjectMed
This enzyme begins the process of degrading proline by starting the reaction that converts it to pyrroline-5-carboxylate.[ ... 2-Methylbutyryl-CoA dehydrogenase deficiency. *Beta-ketothiolase deficiency. *Maple syrup urine disease ... This enzyme helps to break down the pyrroline-5-carboxylate produced in the previous reaction, converting it to the amino acid ... A deficiency of either proline oxidase or pyrroline-5-carboxylate dehydrogenase results in a buildup of proline in the body. A ...
Oxidative stress and glutamate excretion in alcoholic steatosis: Metabolic synapse between hepatocyte and stellate cell
Keywords: Aldehyde dehydrogenase; Alcoholic liver disease; Diacylglycerol lipase; Endocannabinoids; Homocysteine INTRODUCTION. ... where glutamate is converted to pyrroline-5-carboxylate (P5C) through P5C synthase and further metabolized into proline or ... Interestingly, P5C is conversely converted to glutamate by aldehyde dehydrogenase 4 family member A1 (ALDH4A1) [27]. ... which is further metabolized by acetaldehyde dehydrogenase to acetate in the mitochondria of hepatocytes [3]. In chronic ...
Genes | Free Full-Text | Impacts of the Type I Toxin-Antitoxin System, SprG1/SprF1, on Staphylococcus aureus Gene Expression
Pyruvate dehydrogenase E1 component subunit β (PdhB). P99063. 1.84 ↓. 2.23 ↓. 12. Dihydrolipoyl dehydrogenase (PdhD). P99084. ... Glyceraldehyde-3-phosphate dehydrogenase 1 (GapA1). P99136. 1.62 ↓. * the arrow denotes the direction of regulation; ↑ up- and ... Glyceraldehyde-3-phosphate dehydrogenase 1 (GapA1). P99136. 1.5 ↓. 16. 3-hexulose-6-phosphate synthase (HPS). Q7A774. 1.92 ↓. ... Pyruvate dehydrogenase E1 component subunit β (PdhB). P99063. 2.19 ↓. 1.82 ↓. 2. Succinate--CoA ligase (ADP-forming) subunit α ...
Pesquisa | Portal Regional da BVS
Some of the immunodominant antigens include charge variants of EF-Tu, glyceraldehyde-3-phosphate dehydrogenase, ... pyruvate dehydrogenase complex, and others exist as charge variants on two-dimensional gels. These charge variants have similar ... and a dihydrolipoamide dehydrogenase. Alanine racemase and neutral protease were uniquely immunogenic to B. anthracis. ... 5. Identification of human T cell leukemia virus type 1 tax amino acid signals and cellular factors involved in secretion of ...
EurekaMag PDF full texts Chapter 17898
... malate dehydrogenase and lactate dehydrogenase. Applied Microbiology and Biotechnology 40(5): 676-681 ... Baker, P.J.; Sha, J.A.; Mcbride, M.W. 1999: Expression of 3b-hydroxysteroid dehydrogenase type I and type VI isoforms in the ... Davie, J.R.; Wynn, R.Max; Meng, M. 1995: Expression and characterization of branched-chain a-ketoacid dehydrogenase kinase from ... Seong, H.H.; Shiota, K.; Noda, K. 1992: Expression of activities of two 20a-hydroxysteroid dehydrogenase isozymes in rat ...
SMPDB
carboxylate. dehydrogenase,. mitochondrial. Proline. dehydrogenase. 1,. mitochondrial. Pyrroline-5-. carboxylate. reductase 2. ... Pyrroline hydroxycarboxylic. acid. NAD. NADH. ATP. AMP. PP. i. Glycine. Ornithine. Dissipation. Guanidoacetic acid. S- ... 1-Pyrroline-2-carboxylic acid. NH. 3. H. 2. O. 2. H. 2. O. O. 2. 1-Pyrroline-4-hydroxy-2-. carboxylate. NH. 3. H. 2. O. 2. NAD ... 1-Pyrroline-5-carboxylic acid. NAD. H. 2. O. NADH. L-Proline. NAD. NADH. Oxoglutaric acid. O. 2. 4-Hydroxyproline. Succinic ...
PathBank
carboxylate. dehydrogenase,. mitochondrial. Alanine. aminotransferase. 1. Glutamate. dehydrogenase. 1,. mitochondrial. ... pyrroline-5-. ... 5-carboxylic. acid. ATP. NH. 3. ADP. P. i. L-Glutamine. H. 2. O ... dehydrogenase,. mitochondrial. Glutamine--tRNA. ligase. L-Glutamic acid. Carbamoyl phosphate. 5-Phosphoribosylamine. γ- ... 5-phosphate. Magnesium. FAD. Pyridoxal. 5-phosphate. Pyridoxal. 5-phosphate. tRNA(Glu). L-Glutamyl-. tRNA(Glu). tRNA(Gln). L ...
SMPDB
carboxylate. dehydrogenase,. mitochondrial. Proline. dehydrogenase. 1,. mitochondrial. Pyrroline-5-. carboxylate. reductase 2. ... Pyrroline hydroxycarboxylic. acid. NAD. NADH. ATP. AMP. PP. i. Glycine. Ornithine. Guanidoacetic acid. S-Adenosylmethionine. S- ... 1-Pyrroline-2-carboxylic acid. NH. 3. H. 2. O. 2. H. 2. O. O. 2. 1-Pyrroline-4-hydroxy-2-. carboxylate. NH. 3. H. 2. O. 2. NAD ... 1-Pyrroline-5-carboxylic acid. NAD. H. 2. O. NADH. L-Proline. NAD. NADH. Oxoglutaric acid. O. 2. 4-Hydroxyproline. Succinic ...
BiGG Metabolite 1pyr5c c in iAF987
MeSH Browser
Pyrroline Carboxylate Reductases [D08.811.682.662.695] * Saccharopine Dehydrogenases [D08.811.682.662.750] * Tetrahydrofolate ... Methylenetetrahydrofolate Dehydrogenase (NAD+) [D08.811.682.662.217] * Methylenetetrahydrofolate Dehydrogenase (NADP) [D08.811. ... Pyridoxine-5-Phosphate Oxidase Narrower Concept UI. M0018245. Registry Number. 0. Terms. Pyridoxine-5-Phosphate Oxidase ... Pyridoxine-5-Phosphate Oxidase Pyridoxinephosphate Oxidase Registry Number. EC 1.4.3.5. CAS Type 1 Name. Pyridoxamine 5- ...