Deuterated 1-α25-Dihydroxyvitamin D3 solution. Empirical Formula (Hill Notation). : C27D3H41O3. CAS No.. : 128723-16-0. ... 3-epi-25-Hydroxyvitamin D3 (6,19,19-d3) solution. Empirical Formula (Hill Notation). : C27D3H41O2. Molecular Weight. : 403.66. ... 1,25-Dihydroxyvitamin D3-13C3 (25,26,27-13C3) solution. Empirical Formula (Hill Notation). : 13C3C24H44O3. Molecular Weight. : ... Vitamin D3(6,19,19-d3) solution. Synonym(s). : Calciol (6,19,19-d3) solution, Cholecalciferol (6,19,19-d3) solution ...
Cytochrome P450 family 24 subfamily A member 1 (abbreviated CYP24A1) is a member of the cytochrome P450 superfamily of enzymes ... 62 (4): 192-3. doi:10.1159/000133473. PMID 8440135. Chen KS, Prahl JM, DeLuca HF (May 1993). "Isolation and expression of human ... Transcription of the CYP24A1 gene is markedly inducible by 1,25-(OH)2D3 binding to the vitamin D receptor. The gene has a ... CYP24A1 was identified in the early 1970s and was first thought to be involved in vitamin D metabolism as the renal 25- ...
Simultaneous Quantification of 25-Hydroxyvitamin D3 and 24,25-Dihydroxyvitamin D3 in Rats Shows Strong Correlations between ...
2022 Apr 24;11(9):2387. doi: 10.3390/jcm11092387. J Clin Med. 2022. PMID: 35566512 Free PMC article. Review. ... 2007 Mar;320(3):1119-26. doi: 10.1124/jpet.106.115451. Epub 2006 Dec 20. J Pharmacol Exp Ther. 2007. PMID: 17182978 ... 1994;4(3):223-5. doi: 10.3233/WOR-1994-4312. Work. 1994. PMID: 24440957 No abstract available. ... 1993;3(1):76-7. doi: 10.3233/WOR-1993-3114. Work. 1993. PMID: 24441966 No abstract available. ...
Laitinen K, Lamberg-Allardt C, Tunninen R, Karonen SL, Ylikahri R, Valimaki M. Effects of 3 weeks moderate alcohol intake on ... CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss. ... Chronic ethanol consumption leads to disruption of vitamin D3 homeostasis associated with induction of renal 1,25 ... dihydroxyvitamin D3-24-hydroxylase (CYP24A1). Endocrinology. 2008;149(4):1748-56. https://doi.org/10.1210/en.2007-0903 ...
58(3):528-536.. Lowry MB, Guo C, Zhang Y, Fantacone ML, Logan IE, Campbell Y, Zhang W, Le M, Indra AK, Ganguli-Indra G et al.. ... 58(3):528-536.. Guo C, Gombart AF. 2014. The antibiotic effects of vitamin D.. Endocr Metab Immune Disord Drug Targets. 14(4): ... 24(5):754-9.. Lowry MB, Guo C, Borregaard N, Gombart AF. 2014. Regulation of the human cathelicidin antimicrobial peptide gene ... Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.. J ...
25. Mannie MD, Curtis AD,2. Tolerogenic vaccines for Multiple sclerosis. Hum Vaccin Immunother (2013) 9(5):1032-8. doi: 10.4161 ... 3. Bluestone JA. Mechanisms of tolerance. Immunol Rev (2011) 241(1):5-19. doi: 10.1111/j.1600-065X.2011.01019.x ... 24. Mannie MD, DeOca KB, Bastian AG, Moorman CD. Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3+ ... These preclinical studies led to the initiation of 3 clinical trials using CAR- or CAAR-T cells to deplete pathogenic B cells ...
In one, [3H]24,25(OH)2D3 production reached 2.9 pmol/106 cells per 30 min at 10-6 M 1,25(OH)2D3 (30% normal maximum at 10-6 M 1 ... 24-OHase induction was detectable in normal fibroblasts at ~3 x 10-10 M 1,25(OH)2D3. [3H]24,25(OH)2D3 formation after exposure ... Apparent maximal [3H]24,25(OH)2D3 production in normal cell lines was 9 pmol/106 cells per 30 min and occurred after induction ... In one, [3H]24,25(OH)2D3 production reached 2.9 pmol/106 cells per 30 min at 10-6 M 1,25(OH)2D3 (30% normal maximum at 10-6 M 1 ...
Type 3 transporters were initially identified as viral transport proteins. Almost all cells express type 3 sodium phosphate ... FGF23 production by osteoblasts is stimulated by 1,25 vitamin D. [8] Conversely, individuals with X-linked hypophosphatemic ... As levels of 1,25 vitamin D fall during the development of progressive chronic kidney disease, levels of FGF23 rise inversely. ... Excess free serum phosphate is taken up into vascular smooth muscle via a type 3 sodium-phosphate cotransporter. The increased ...
24(5):754-9.. Lowry MB, Guo C, Zhang Y, Fantacone ML, Logan IE, Campbell Y, Zhang W, Le M, Indra AK, Ganguli-Indra G et al.. ... Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.. J ...
2004 Mar;79(3):362-71.. Hypponen E, Laara E, Reunanen A, Jarvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 ... 2009 Jul;17(3):703-17.. Melamed ML, Michos ED, Post W, Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the ... 2008;25(6):539-43.. Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D(3) and calcium ... 2000;72(3):690-3.. Yin L, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis of longitudinal studies: Serum vitamin D and ...
Diurnal rhythm of plasma 1,25-dihydroxyvitamin D and vitamin D-binding protein in postmenopausal women: relationship to plasma ... Calcif Tissue Res 1977 Oct 20;23(3):241-4. Proliferation of osteoclasts in rat bone following bleeding and femoral fractures. ... Proc Soc Exp Biol Med 1986 Mar;181(3):438-42. Forskolin-induced bone resorption in neonatal mouse calvaria in vitro. ... bone) to PTH and 1,25(OH)2 vitamin D3, Under certain conditions however, magnesium can stimulate bone resorption. A more potent ...
2004 Mar;79(3):362-71.. Hypponen E, Laara E, Reunanen A, Jarvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 ... 2009 Jul;17(3):703-17.. Melamed ML, Michos ED, Post W, Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the ... 2008;25(6):539-43.. Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D(3) and calcium ... 2000;72(3):690-3.. Yin L, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis of longitudinal studies: Serum vitamin D and ...
We hypothesized that catabolism of 25(OH)D3 to 24,25(OH)2D3 would be greater in the bolus than in the daily dose group. Design ... Greater breast milk vitamin D3 values in the single dose group were inversely associated with the 24,25(OH)2D3/25(OH)D3 ratio ( ... Results: The concentration of serum 24,25(OH)2D3 was directly related to that of 25(OH)D in both groups (r2 = 0.63; p , 0.001 ... A daily dose of vitamin D may have more lasting effectiveness in increasing 25(OH)D3 with lesser diversion of 25(OH)D3 to 24,25 ...
This means that the time earlier than complete re?titration is critical due to this fact varies between 3 and 7 days, relying ... J Clin Psychopharmacol 33(3):329-335, 2013 23609380 Bitter I, Katona L, Zambori J, et al: Comparative effectiveness of depot ... Accordingly, the metabolic alterations allowing biosynthesis of p-toluate, terephthalate or (2-hydroxy-3-methyl-4-oxobutoxy) ... Function: Dorsiflexion (1); extengroup 3: (1) Pyriformis; (2) gemellus (superior or sion of toes (2); stabilization of arch (3 ...
Dihydroxyvitamin D3 to patients with Postmenopausal Osteoporosis: Short- and long-term Effects on Bone and Calcium Metabolism. ... 25dihydroxyvitamin D . Am Soc Bone Mineral Research at Austin, Texas.2022 October 2022 ... 25dihydroxyvitamin D levels in normal women. Calcif Tissue Int. 60, p. 491-495 1997 ... Supplement, p. 3-9 1994. *Bush TL, Dawood MY, Gallagher JC, Hulka BS, Lindsay R, Utian WH. Tailoring the regimen to the patient ...
1,25-(OH)2-D3 has also been found to enhance the activity of some vitamin D-receptor positive immune cells and to enhance the ... 32222-06-3. InChI Key. GMRQFYUYWCNGIN-NKMMMXOESA-N. InChI. InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23 ... 1,25-(OH)2-D3 has demonstrated beneficial effects in animal models of such autoimmune diseases as rheumatoid arthritis. Vitamin ... Ohter identified metabolites of calcitriol include 1α, 25(OH)2-24-oxo-D3; 1α, 23,25(OH)3-24-oxo-D3; 1α, 24R,25(OH)3D3; 1α, 25S, ...
"Dihydroxyvitamin D" OR "Dihidroxivitamina D" OR "Dihidroxivitaminas D" OR "Di-Hidroxivitamina D" OR "Di-Hidroxivitaminas D" OR ... "24,25-Di-Hidroxivitamina D 3" OR ((3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol) OR "25(OH)D" OR "1,25 Hydroxyvitamin" ... OR "1,25 Hidroxivitamin" OR "1-25 Hydroxyvitamin" OR "1-25 Hidroxivitamin" OR "1,25(OH)D" OR "1-25(OH)D" OR Calciol OR ... 25-Dihydroxyvitamin D 3" OR mh:"Vitamin D Deficiency" OR tw:("Vitamin D" OR "Vitamina D" OR Cholecalciferol OR Colecalciferol ...
Fri Apr 24 00:00:00 EDT 2020. Influenza NG-34 T cell conserved epitope adjuvanted with CAF01 as a possible influenza vaccine ... Wed Nov 24 00:00:00 EST 2010. 1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect ... Tue Nov 24 00:00:00 EST 2020. IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and ... Tue May 25 00:00:00 EDT 2021. M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 ...
2010;28(3):342-350.. 81 Booth SL, Dallal G, Shea MK, et al. Effect of vitamin K supplementation on bone loss in elderly men and ... 2007;22(3):286.. 27 Tucker LA, Nokes N, Adams T. Effect of a dietary supplement on hip and spine BMD: a randomized, double- ... 2001;11(1-3):23-45.. 86 Heldin, CH, Miyazono, K, ten Dijke, P. TGF-beta signalling from cell membrane to nucleus through SMAD ... 1995;53(3):71-74.. 35 Stendig-Lindberg G, Tepper R, Leichter I. Trabecular bone density in a two year controlled trial of ...
When calcipotriene was applied topically to mice for up to 24 months at dosages of 3, 10 and 30 µg/kg/day (corresponding to 9 ... The active form of the vitamin, 1,25-dihydroxy vitamin D3 (calcitriol), is known to be recycled via the liver and excreted in ... There is evidence that maternal 1,25-dihydroxy vitamin D3 (calcitriol) may enter the fetal circulation, but it is not known ... Chemically, calcipotriene is (5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19), 22-tetraene-1α,3β,24-triol-, with the ...
We found a significant fall in the level of 1,25-dihydroxyvitamin D (p less than 0.01) and a significant increase in the molar ... The authors report 3 patients affected by psoriasiform acral dermatitis, a distinctive clinical entity characterized by a ... The effects of one weeks daily treatment with dexchlorpheniramine (3 + 3 mg x 2) and loratadine (10 mg x 2) on the cutaneous ... Indomethacin and piroxicam markedly inhibited the erythema at 6 to 24 h after irradiation but erythema reappeared at 45 h. The ...
24,24-difluoro-9,10-secocholesta-5,7,10-triene-1,3,25-triol (C27H42F2O3) from the PQR. ... C27H42F2O3. IUPAC Name. (3z)-3-[(2e)-2-[(1r,3as,7ar)-1-[(1r)-4,4-difluoro-5-hydroxy-1,5-dimethyl-hexyl]-7a-methyl-2,3,3a,5,6,7- ... 1R,3S,5Z,7E)-24,24-Difluoro-9,10-Secocholesta-5,7,10-Triene-1,3,25-Triol ... 1s,3r,5z)-5-[(2e)-2-[(1r,3as,7ar)-1-[(1r)-4,4-difluoro-5-hydroxy-1,5-dimethyl-hexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden- ...
Results Higher 25-hydroxyvitamin D concentrations in mid-gestation were associated with a higher forced vital capacity (FVC), ... Furthermore, higher 25-hydroxyvitamin D concentrations in mid-gestation were associated with an increased risk of inhalant ... Objective We examined the associations of 25-hydroxyvitamin D concentrations in mid-gestation and at birth with lung function, ... Maternal venous blood samples in mid-gestation and umbilical cord blood samples at birth were used to determine 25- ...
... dihydroxyvitamin D(3) 24‐hydroxylase; CX32, gap junction connexin‐32.2 protein; CYLC1, cylicin‐1; Dio1; DSC1, desmocollin‐1; ... dihydroxyvitamin D(3) 24‐hydroxylase; CX32, gap junction connexin‐32.2 protein; CYLC1, cylicin‐1; Dio1; DSC1, desmocollin‐1; ... Gene names are as follows: "14.3.3.a, 14‐33.a protein; APOC1, apolipoprotein C‐I; APOM, apolipoprotein M; AQP‐3, aquaporin‐3; ... Gene names are as follows: "14.3.3.a, 14‐33.a protein; APOC1, apolipoprotein C‐I; APOM, apolipoprotein M; AQP‐3, aquaporin‐3; ...
Project Title: 24,25-Dihydroxyvitamin D in CRIC. UWashington PI: KESTENBAUM. Start: 4/1/2016. End: 3/31/2020. Project Title: ... End: 3/31/2028. Project Title: Development of a Kidney Biomarker Panel to Detect and Quantify NSAID Damage among Persons with ... End: 3/31/2023. Project Title: The role of iron deficiency in cardiac and diabetic complications of CKD ... End: 3/31/2016. Project Title: Validation of the Kidney Knowledge Survey (KIKS) in Hispanics with CKD ...
doi:10.1007/978-3-642-10858-7_13. *Chen P, Hu P, Xie D, Qin Y, Wang F, Wang H. Meta-analysis of vitamin D, calcium and the ... The half-life of 1,25(OH)2D is only 4 to 6 hours and 1000-fold less than the total 25(OH)D. So, serum vitamin D is usually ... He showed that 25(OH)D concentration values are only useful for short follow-up times for breast cancer as it develops rapidly ... The 25(OH)D is then transported in the circulation by the vitamin D-binding protein and further metabolized in kidneys to ...
The biological activity and structure of (22S)-1α,25-dihydroxy-17,20-dien-24-homo-21-nor-vitamin D3 bound to binding domain of ... We have designed and synthesized the first examples of 1α,25-dihydroxyvitamin D3 analogs bearing an allenic unit attached to ... Dihydroxyvitamin D 3 Analogs with Locked Mobility at C‐17. Chemistry - A European Journal, 2021, 27 (53), pp.13384-13389. ⟨ ... Dihydroxyvitamin D 3 Analogs with Locked Mobility at C‐17. ... 3 Universidade do Porto = University of Porto 4 Universidade da ...
... dihydroxy vitamin D3 on the expressions of vascular endothelial growth factor and transforming growth factor-b1 in the retinas ... Dihydroxyvitamin D3, an inducer of glial cell line-derived neurotrophic factor. NeuroReport. 1996;7(13):2171-5. v1996 ... 24. ; Intervention 56. ; Meta-analysis 38. ; Obesity 34. ; Pregnancy 43. ; T1 (child) 39. ; Omega-3 11. ; Vitamin D Receptor 23 ... 2013;44(3):235-41 CrossRefGoogle Scholar *10 Pilz S, Kienreich K, Rutters F, et al. Role of vitamin D in the development of ...
It is best not to let puppies or kittens nurse for 12-24 hours after the bitch or queen is treated for hypocalcemia. During ... After the acute crisis, elemental calcium at 25-50 mg/kg per day orally in three or four divided doses is given for the ... The dosage of 1,25-dihydroxyvitamin D3 (calcitriol) is 0.03-0.06 mcg/kg per day. Calcitriol has a rapid onset of action (1-4 ... This is a much briefer period than that observed with the use of dihydrotachysterol (1-3 weeks) or ergocalciferol (vitamin D2; ...