Human 4-1BB Ligand (TNFSF9), Animal-Free Recombinant Protein, PeproTech®  at Fishersci.com ... ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5 A; tumor ... CD 137 Ligand; CD 137 L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1 BB-L; Ly63l; ... CD137 ligand (CD137L) is a type II membrane protein and part of the TNF superfamily. CD137L is a co-stimulatory molecule that ...

PE anti-mouse 4-1BB Ligand (CD137L) Antibody - 4-1BB ligand, also known as CD137L, is a 97 kD member of the TNF superfamily ... Ligand/Receptor 4-1BB (CDw137) Cell Type B cells, Dendritic cells, Macrophages, T cells Biology Area Costimulatory Molecules, ... 4-1BBL, CD137L, TNFSF9, 4-1BB Ligand Isotype Rat IgG2a, κ Ave. Rating Submit a Review Product Citations publications Mouse B ... 4. Pollok KE, et al. 1994. Eur. J. Immunol. 24:367.. 5. Goodwin RG, et al. 1993. Eur. J. Immunol. 23:2631. ...

Human 4-1BB Ligand / TNFSF9 (71-254) Protein, Fc Tag, active trimer, premium grade (41L-H5269) by ACRO Biosystems ... Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine ... Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine ... As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.. Accession:. NP_003802.1. ...

The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T ... "4-1BB Ligand" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "4-1BB Ligand" by people in this website by year, and whether " ... Below are the most recent publications written about "4-1BB Ligand" by people in Profiles. ...

Tumor expression of 4-1BB ligand sustains tumor lytic T cells. / Zhang, Hua; Merchant, Melinda S.; Chua, Kevin S. et al. In: ... Tumor expression of 4-1BB ligand sustains tumor lytic T cells. In: Cancer Biology and Therapy. 2003 ; Vol. 2, No. 5. pp. 579- ... Tumor expression of 4-1BB ligand sustains tumor lytic T cells. Hua Zhang, Melinda S. Merchant, Kevin S. Chua, Chand Khanna, Lee ... Tumor expression of 4-1BB ligand sustains tumor lytic T cells. Cancer Biology and Therapy. 2003 Sep;2(5):579-586. doi: 10.4161/ ...

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"Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell ... DeBenedette, M. A.; Shahinian, A.; Mak, T. W.; Watts, T. H. (1997). "Costimulation of CD28- T lymphocytes by 4-1BB ligand". ...

The 4B4-1 monoclonal antibody specifically binds to CD137 which is also known as 4-1BB, and ILA (induced by lymphocyte ... The 4B4-1 monoclonal antibody specifically binds to CD137 which is also known as 4-1BB, and ILA (induced by lymphocyte ... Development References (4). * Garni-Wagner BA, Lee ZH, Kim YJ, Wilde C, Kang CY, Kwon BS. 4-1BB is expressed on CD45RAhiROhi ... Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8(+) T cells. J Hematother Stem Cell Res. 2001; 10(4):441- ...

Shi Yong Neo,1 Ying Yang,1,2 Julien Record,3 Ran Ma,1 Xinsong Chen,1 Ziqing Chen,1 Nicholas P. Tobin,1 Emily Blake,4 Christina ... To inhibit STAT3, the selective small-molecule inhibitor GPB730 (N-[(4R,7R,9R,11S)-11-hydroxy-9-methyl-2-oxo-3-oxatricyclo [5.3 ... Figure 4. Tumor cells stimulate NK cells to translocate CD73 into the cell membrane and the extracellular space. (A) Maximum ... Scale bar: 10 μm (n = 4). (B) Overall mean fluorescence intensity (MFI) of CD73 staining per cell comparing CD73+ and CD73- NK ...

Regulation of Fas and Fas-ligand expression in NK cells by cytokines and the involvement of Fas-ligand in NK/LAK cell-mediated ... They can be activated rapidly via germ-line encoded receptors that recognize the presence of stress ligands or absence of self- ... Functional NK cell repertoires are maintained through IL-2Rα and Fas ligand. J Immunol (2014) 192:3889-97. doi:10.4049/jimmunol ... In parallel with the changes in CD16 expression, apoptosis-mediating receptors and ligands such as TRAIL, FAS, and FAS-L were ...

Programmed death ligand 1 (PD-L1) is expressed on the surface of tumor cells and its level is a key determinant of the ... and OX-40 ligand (OX-40L/CD252) are important regulators of effector cytotoxic T-cells activity. This study demonstrates that ... is suppressed while expression of immunosuppressive molecule programmed death ligand-1 (PD-L1/CD274) is enhanced in ... 2018; 52(4):1305-1316 [PubMed] Related Publications A-kinase anchor protein 12 (AKAP12; also known as Gravin) functions as a ...

EPH-related receptor tyrosine kinase ligand 1; Immediate early response protein B61;Epgl1; Epl1; Lerk1Gene Names:... ... 4-1BB ligand receptor;CDw137;T-cell antigen... ... EPH-Related Receptor Tyrosine Kinase Ligand 4; LERK-4; EFNA4; ...

Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary ...

The 4-1BB receptor (CDw137), a member of the tumor necrosis factor receptor superfamily, has been shown to costimulate the ... 6E9 is a rat IgG2A anti-human CD40 ligand mAb that does not react with mouse CD40 ligand and was provided by Dr. Tony Siadak ( ... ELISAs for monitoring ligand blocking of 4-1BB-Ig were performed as described previously 8. For anti-SRBC responses, mice were ... I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions ...

... lability of ligand X, and strength of plati- num-acetamide bond), the oopening complexes were later formulated as [Pt2{CH3C(O) ... 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses. Dose prediction in ...

4: Methylation analysis of CNN2 gene in ESCA (A): Waterfall plot of the methylation level of the CNN2 gene. The correlations ... 4, results of survival analysis also showed that higher DNA methylation level of CpG at cite cg22902083 correlated with better ... Immobilized MHC class I chain-related protein A synergizes with IL-15 and soluble 4-1BB ligand to expand NK cells with high ... A total of 14 methylation sites were found (Table 4). Among them, cg22902083 had a significant correlation with the prognosis ...

... trimerizes upon binding to CD137 ligand (CD137L) to induce cell stimulatory transcriptional and epigenetic changes.1 2 The ... 4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the ... Background CD137 (4-1BB) represents a costimulatory pathway that promotes T, NK, and dendritic cell effector functions ... Segal, N.H., et al., Phase I study of single-agent utomilumab (PF-05082566), a 4-1BB/CD137 agonist, in patients with advanced ...

The antibody can also be used to isolate cells that have an FITC-labeled ligand on their surface. ... F910 Tosoh R40 and R28 Protein A Mix-N-Go ELISA Kit is intended for use in quantitating the recombinant Protein A ligands used ... F965 Avantor Protein A Mix-N-Go ELISA Kit is intended for use in quantitating the recombinant Protein A ligands used in the ... 4-1BB Receptor/TNFRSF9, human, RC214-25R, Bio Basic Storage Condition : -15~-20℃ Shipping Condition : RT ...

4-1BB Receptor/TNFRSF9, human, RC214-25R, Bio Basic Storage Condition : -15~-20℃ Shipping Condition : RT ... 4-1BB Ligand/TNFSF9, human, RC214-25, Bio Basic Storage Condition : -15~-20℃ Shipping Condition : RT ...

CD137 Ligand Tumor Necrosis Factor (Ligand) Superfamily, Member 9 Tumor Necrosis Factor Ligand Superfamily Member 9 ... CD137 Ligand. Tumor Necrosis Factor (Ligand) Superfamily, Member 9. Tumor Necrosis Factor Ligand Superfamily Member 9. ... Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.644.276.374.750.656] Tumor Necrosis Factor Ligand Superfamily Member 13 ... Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.644.276.374.750.690] Tumor Necrosis Factor Ligand Superfamily Member 14 ...

Product Information Construction A DNA sequence encoding the human FLT3 Ligand（NP_001450.2）was expressed with a His tag at the ... FLT3 ligand is a growth factor that regulates the proliferation of early hematopoietic cells. FLT 3-ligand binds to cells ... Unlike SCF, FLT3 ligand has no effect on mast cells. Multiple subtypes of FLT3-ligands have been identified. ... The FLT3 ligand itself does not stimulate the proliferation of early hematopoietic cells, but rather synergistically induces ...

It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is… ... It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is ... It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is ... a CD19 Targeted 4-1BB Ligand) in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment ...

4-1BB Receptor 20. Target. Target. 4-1BB Ligand 135. 9. 0.17. -0.72. 0.45. 0.85. ...

GITR Ligand GM-CSF GPR183 GPR19 GPR56 GPR83 Granulysin Granzyme A Granzyme K H-2 H-2Db H-2Dd H-2Dk H-2Kb H-2Kb bound to ... 3C4 (mIC2/4) 3C7 3D12 3D4 3D6.112 3E12 3E7 3F3 3F9 3G7A02 3G8 3H5 41A 429 (MVCAM.A) 42D1 43A3 47 49-H4 4A6 4A9 4B12 4B2.9 4B4-1 ... HIM3-4 HIM6 HIP1 HIP2 HIP8 HIR2 HIT2 HIT3a HIT8a HK1.4 HK5.3 HLADQ1 HLy-9.1.25 HM-CCR5 HM34 HM36 HM40-3 HM47 HM48-1 HM79-12 HM? ... DJR2-4 (7-8) DJR3 DL-101 DOR7D2A4 DREG-56 DTA-1 Duha59 Duno85 DX2 DX22 DX27 DX5 DX9 E11 E11/19 E13-161.7 E18 E8N1 Eat-2 EBVCS-5 ...

4. Target. Target. Exodus-3 8. 1. 0.18. -0.81. 0.25. 0.89. CCL5 2,002. Target. Target. CCL3 1,427. 500. 0.30. -0.70. 0.35. 0.89 ... 4. Target. Target. Exodus-2 27. 1. 0.10. -0.85. 0.25. 0.84. 4-1BB Ligand 135. Target. Target. CD137 474. 33. 0.13. -0.84. 0.24 ... 4-1BB Receptor 20. Target. Target. 4-1BB Ligand 135. 9. 0.17. -0.72. 0.45. 0.85. ... BMP-4 1,255. Target. Target. BMP-2 3,889. 399. 0.18. -0.78. 0.32. 0.83. ...

Ligand ...

Evaluation of OX40 Ligand as a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL1 ... Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. Proc. Natl. Acad ... B7.1 is the classic costimulatory ligand, acting with its receptor CD28 to provide the second signal required for T cell ... The titration of influenza peptide from 2 to 0.1 μM with the different costimulatory ligands was also conducted for three ...

Residual Affinity Ligands Detection Kits. *Residual Cell Culture Materials Detection Kits. *Residual Enzyme ELISA Kit ... PD-L1x4-1BB; DuoBody-PD-L1x4-1BB; GEN1046; BNT-311. Phase 2 Clinical. Genmab A/S, Biontech Se. Solid tumours; Squamous Cell ... Immobilized Human 4-1BB Ligand, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. 41L-H5254) at 2 μg/mL (100 μL/well) can bind ... Immobilized Biotinylated Human 4-1BB, Fc,Avitag (Cat. No. 41B-H82F8) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN- ...

4-1BB-mediated immunotherapy of rheumatoid arthritis. Seo SK, Choi JH, Kim YH, Kang WJ, Park HY, Suh JH, Choi BK, Vinay DS, ... Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis. Seo SK, Park HY, Choi JH, Kim WY, Kim YH, Jung HW ... 4. The tryptophan metabolite 3-hydroxyanthranilic acid suppresses T cell responses by inhibiting dendritic cell activation. Lee ... 7. Protective role of V-set and immunoglobulin domain-containing 4 expressed on kupffer cells during immune-mediated liver ...