Parsons SJ, Burns RO (February 1969). "Purification and Properties of β-Isopropylmalate Dehydrogenase". J. Biol. Chem. 244 (3 ... is an enzyme that is a part of the isopropylmalate dehydrogenase family, which catalyzes the chemical reactions: (2R,3S)-3- ... isopropylmalate + NAD+ ⇌ {\displaystyle \rightleftharpoons } 4-methyl-2-oxopentanoate + CO2 + NADH (2R,3S)-3-isopropylmalate + ... Calvo JM, Stevens CM, Kalyanpur MG, Umbarger HE (December 1964). "The Absolute Configuration of α-carboxyisocaproic Acid (3- ...
... (isopropylmalate) is an intermediate in the biosynthesis of leucine, synthesized from oxoisovalerate by 2- ... isopropylmalate synthase and converted into isopropyl-3-oxosuccinate by 3-isopropylmalate dehydrogenase. Two isomers are ... and these are interconverted by isopropylmalate dehydratase. Strassman, Murray; Ceci, Louis N. (1963). "Enzymatic Formation of ... doi:10.1016/S0021-9258(19)67991-3. PMID 13978769. (Chemical articles with multiple compound IDs, Chemicals using indexlabels, ...
Isocitrate/isopropylmalate dehydrogenase family The isocitrate dehydrogenase 3 isozyme is a heterotetramer that is composed of ... Eukaryotic isocitrate dehydrogenase enzymes on the other hand, have not been fully discovered yet. Each dimer of IDH has two ... Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of ... Isocitrate dehydrogenase: RCSB PDB Molecule of the Month Archived 2013-12-24 at the Wayback Machine Overview of all the ...
... malate dehydrogenase MeSH D08.811.682.047.748 - malate dehydrogenase (nadp+) MeSH D08.811.682.047.892 - xanthine dehydrogenase ... 2-isopropylmalate synthase MeSH D08.811.913.050.618 - malate synthase MeSH D08.811.913.050.622 - 3-oxoacyl-(acyl-carrier- ... acetoin dehydrogenase MeSH D08.811.682.047.070 - alcohol dehydrogenase MeSH D08.811.682.047.150 - carbohydrate dehydrogenases ... acyl-coa dehydrogenase MeSH D08.811.682.660.150.150 - acyl-coa dehydrogenase, long-chain MeSH D08.811.682.660.150.200 - acyl- ...
112 (3): 417-429. doi:10.1111/j.1365-2672.2011.05204.x. ISSN 1364-5072. PMID 22121830. La Duc, Myron T; Satomi, Masataka; Agata ... 56 (3): 383-394. doi:10.1016/j.mimet.2003.11.004. ISSN 0167-7012. PMID 14967230. Patel, Sudip; Gupta, Radhey S. (2020-01-01). " ... 49 (3): 1083-1090. doi:10.1099/00207713-49-3-1083. ISSN 1466-5026. PMID 10425765. Shida, O.; Takagi, H.; Kadowaki, K.; Komagata ... 3-oxoacid CoA-transferase subunit B, LTA synthase family protein, sulphate ABC transporter permease subunit CysW, class I SAM- ...
A series of four more enzymes - isopropylmalate synthase, isopropylmalate isomerase, isopropylmalate dehydrogenase, and ... dihydroxyacid dehydrogenase and aminotransferase. Threonine dehydrogenase catalyzes the deamination and dehydration of ... Dihydroxyacid dehydrogenase converts the dihyroxyacids in the next step. The final step in the parallel pathway is conducted by ... BCAAs are broken down effectively by dehydrogenase and decarboxylase enzymes expressed by immune cells, and are required for ...
The third step is the NAD+-dependent oxidation of β-isopropylmalate catalyzed by a dehydrogenase. The final step is the ... α-Isopropylmalate synthase catalyzes this condensation with acetyl CoA to produce α-isopropylmalate. An isomerase converts α- ... PheA uses a simple dehydrogenase to convert prephenate to phenylpyruvate, while TyrA uses a NAD-dependent dehydrogenase to make ... Relevant enzymes include aspartokinase, aspartate-semialdehyde dehydrogenase, homoserine dehydrogenase, homoserine O- ...
EC 1.1.1.1: alcohol dehydrogenase EC 1.1.1.2: alcohol dehydrogenase (NADP+) EC 1.1.1.3: homoserine dehydrogenase EC 1.1.1.4: (R ... L-arabinitol 4-dehydrogenase EC 1.1.1.13: L-arabinitol 2-dehydrogenase EC 1.1.1.14: L-iditol 2-dehydrogenase EC 1.1.1.15: D- ... L-rhamnose 1-dehydrogenase [NAD(P)+] EC 1.1.1.379: (R)-mandelate dehydrogenase EC 1.1.1.380: L-gulonate 5-dehydrogenase EC 1.1. ... uronate dehydrogenase EC 1.2.1.36: retinal dehydrogenase EC 1.2.1.37: Now EC 1.17.1.4, xanthine dehydrogenase EC 1.2.1.38: N- ...
Acetolactate synthase Acetohydroxy acid isomeroreductase Dihydroxyacid dehydratase α-Isopropylmalate synthase α-Isopropylmalate ... Isovaleryl-CoA is subsequently metabolized by isovaleryl-CoA dehydrogenase and converted to MC-CoA, which is used in the ... whereas the dehydrogenase enzyme is found exclusively in the mitochondrion (Sabourin and Bieber 1981, 1983). Importantly, this ... whereas the dehydrogenase enzyme is found exclusively in the mitochondrion (Sabourin and Bieber 1981, 1983). Importantly, this ...
... isocitrate dehydrogenase (NADP+)] kinase EC 2.7.1.117: Now EC 2.7.11.18, myosin-light-chain kinase EC 2.7.1.118: ADP-thymidine ... 2-isopropylmalate synthase EC 2.3.3.14: homocitrate synthase EC 2.3.3.15: sulfoacetaldehyde acetyltransferase EC 2.3.3.16: ... pyruvate dehydrogenase (acetyl-transferring)] kinase EC 2.7.1.100: S-methyl-5-thioribose kinase EC 2.7.1.101: tagatose kinase ... isocitrate dehydrogenase (NADP+)] kinase EC 2.7.11.6: [tyrosine 3-monooxygenase] kinase EC 2.7.11.7: myosin-heavy-chain kinase ...