Flanking SNPs are Single nucleotide polymorphisms (SNP) that appear in the flanking region. Polymorphisms in this region can ... flanking region is a region of DNA that is adjacent to the 5′ end of the gene. The 5flanking region contains the promoter, ... flanking region of eukaryotic genomes. A specific transcription factor called CAAT-binding protein binds to this region and ... untranslated region, this region is not transcribed into RNA or translated into a functional protein. These regions primarily ...
... flanking region". Journal of Biological Chemistry. 260 (8): 5055-60. doi:10.1016/S0021-9258(18)89178-5. PMID 2580830. Ruoslahti ... 7 (5): 267-9. doi:10.1055/s-2008-1071168. PMID 9402482. Lee PI, Chang MH, Chen DS, Lee CY (January 1989). "Serum alpha- ... The normal range of AFP for adults and children is variously reported as under 50, under 10, or under 5 ng/mL. At birth, normal ... 26 (5): 1332-43. doi:10.1021/bi00379a020. PMID 2436661. Sakai M, Morinaga T, Urano Y, et al. (1985). "The human alpha- ...
... flanking region of human MRP3". Biochem. Biophys. Res. Commun. 270 (3): 728-32. doi:10.1006/bbrc.2000.2507. PMID 10772892. Nies ... flanking region, genomic organization and alternative splice variants". Biochim. Biophys. Acta. 1415 (2): 369-74. doi:10.1016/ ... 5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMC 395752. PMID 14759258. Lang T, Hitzl M, Burk O, Mornhinweg E, Keil A, Kerb R, Klein ... 290 (5): 1427-33. doi:10.1006/bbrc.2002.6367. PMID 11820781. Scheffer GL, Kool M, de Haas M, de Vree JM, Pijnenborg AC, Bosman ...
... flanking region and active promoter". The Journal of Biological Chemistry. 263 (32): 16992-8. doi:10.1016/S0021-9258(18)37488-X ... "Two regions in human DNA polymerase beta mRNA suppress translation in Escherichia coli". Nucleic Acids Research. 20 (18): 4859- ... 93 (5): 507-12. doi:10.1007/bf00202813. PMID 8168825. S2CID 34824853. Chyan YJ, Strauss PR, Wood TG, Wilson SH (August 1996). " ... 243 (5408): 441-5. Bibcode:1973Natur.243..441O. doi:10.1038/243441a0. PMID 4591306. S2CID 4153800. Cabelof DC, Raffoul JJ, ...
... flanking region by deletion/substitution". J. Biol. Chem. 263 (24): 12020-7. doi:10.1016/S0021-9258(18)37887-6. PMID 3042787. ... untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common ... "Complex arrangement of genes within a 220-kb region of double-duplicated DNA on human 2q37.1". Genomics. 73 (1): 50-5. doi: ... 261 (7): 3112-5. doi:10.1016/S0021-9258(17)35755-1. PMID 3512548. Ezra E, Blacher R, Udenfriend S (1984). "Purification and ...
... flanking region element responsible for the low level constitutive expression of the human cytosolic phospholipase A2 gene". ... flanking region surrounding a human cytosolic phospholipase A2 gene". Biochemical and Biophysical Research Communications. 205 ... 19 (4-5): 683-688. PMID 9745929. Hirabayashi T, Murayama T, Shimizu T (2005). "Regulatory mechanism and physiological role of ... 58 (5-6): 328-333. doi:10.1080/15216540600702289. PMID 16754327. S2CID 36287675. Sharp JD, White DL, Chiou XG, et al. (1991). " ...
... flanking region". J. Biol. Chem. 269 (7): 5279-87. doi:10.1016/S0021-9258(17)37685-8. PMID 8106512. Harada H, Kitagawa M, ... 40 (5): 976-82. PMID 10102295. Whitney LW, Becker KG, Tresser NJ, Caballero-Ramos CI, Munson PJ, Prabhu VV, Trent JM, McFarland ... 35 (5-6): 507-11. doi:10.1080/10428199909169615. PMID 10609788. Staal A, Enserink JM, Stein JL, Stein GS, van Wijnen AJ (2000 ... Intron-exon organization and functional analysis of 5'- ...
... flanking region of the human PTK6 gene". Biochim. Biophys. Acta. 1574 (3): 365-9. doi:10.1016/s0167-4781(02)00234-8. PMID ... 5 (7): 1767-77. PMID 10430081. Derry JJ, Richard S, Valderrama Carvajal H, et al. (2000). "Sik (BRK) Phosphorylates Sam68 in ... Kang KN, Kim M, Pae KM, Lee ST (2002). "Characterization of the 5'- ...
... flanking region of human aggrecanase-1 (ADAMTS4) gene". Molecular Biology Reports. 27 (3): 167-73. doi:10.1023/A:1007253930568 ... Adjacent to the C-terminal TSR is a disintegrin-like domain, a cysteine-rich region that stacks against the active-site of the ... Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a ... 5 (3): 169-76. doi:10.1093/dnares/5.3.169. PMID 9734811. Tortorella MD, Burn TC, Pratta MA, Abbaszade I, Hollis JM, Liu R, ...
... flanking region". The Journal of Biological Chemistry. 262 (28): 13662-13673. doi:10.1016/S0021-9258(19)76478-3. PMID 2888762. ... flanking region". The Journal of Biological Chemistry. 262 (28): 13662-13673. doi:10.1016/S0021-9258(19)76478-3. PMID 2888762. ... and a proline-rich region, and its light chain contains the protease domain. The structure of the FnI-EGF-like tandem domain of ... 2 (5): 549-558. doi:10.1182/bloodadvances.2018016337. PMC 5851424. PMID 29519898. Pathak M, Wilmann P, Awford J, Li C, Hamad BK ...
... flanking regulatory region". Gene. 294 (1-2): 259-68. doi:10.1016/S0378-1119(02)00798-9. PMID 12234688. Tiffin N, Williams RD, ... "The genomic organization and the full coding region of the human PAX7 gene". Genomics. 45 (1): 168-74. doi:10.1006/geno. ... 5 (1): 15-21. doi:10.1093/hmg/5.1.15. PMID 8789435. Vorobyov E, Mertsalov I, Dockhorn-Dworniczak B, Dworniczak B, Horst J ( ... "Structural and functional characterization of the human PAX7 5'- ...
... flanking region of the human beta-glucuronidase gene". Genomics. 10 (4): 1009-18. doi:10.1016/0888-7543(91)90192-H. PMID ... Marathe SV, McEwen JE (February 1995). "Vectors with the gus reporter gene for identifying and quantitating promoter regions in ... 274 (33): 23451-5. doi:10.1074/jbc.274.33.23451. PMID 10438523. Wong AW, He S, Grubb JH, Sly WS, Withers SG (December 1998). " ... 2 (6): 443-5. doi:10.1002/humu.1380020604. PMID 8111412. S2CID 46432543. Wu BM, Sly WS (1994). "Mutational studies in a patient ...
... flanking regulatory region of the murine serotonin transporter". Brain Research. Molecular Brain Research. 44 (2): 286-92. doi: ... 4 (5): 645. doi:10.1021/cn4001044. PMC 3656756. PMID 23862750. Alivisatos AP, Andrews AM, Boyden ES, Chun M, Church GM, ... Bengel D, Heils A, Petri S, Seemann M, Glatz K, Andrews A, Murphy DL, Lesch KP (March 1997). "Gene structure and 5'- ...
... flanking region of human genomic ETA gene". Biochemical and Biophysical Research Communications. 190 (2): 332-9. doi:10.1006/ ... 56 Suppl 5: 1303-7. doi:10.1253/jcj.56.supplementv_1303. PMID 1291713. Hosoda K, Nakao K, Tamura N, Arai H, Ogawa Y, Suga S, ... Yang H, Tabuchi H, Furuichi Y, Miyamoto C (January 1993). "Molecular characterization of the 5'- ...
... flanking region, and chromosomal localization of the human RGS3 gene". Genomics. 45 (2): 429-33. doi:10.1006/geno.1997.4929. ... 2002). "RGS3 interacts with 14-3-3 via the N-terminal region distinct from the RGS (regulator of G-protein signalling) domain ... 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of ... 2002). "Additional 5' exons in the RGS3 locus generate multiple mRNA transcripts, one of which accounts for the origin of human ...
... flanking region of the human estrogen receptor gene". DNA Sequence. 2 (6): 347-358. doi:10.3109/10425179209020816. PMID 1476547 ... genomic organization of the human ERalpha gene promoter region". Molecular Endocrinology. 15 (12): 2057-2063. doi:10.1210/mend. ... 70 (5-7): 361-363. doi:10.1016/j.steroids.2005.02.015. PMID 15862818. S2CID 54297122. Wang CL, Tang XY, Chen WQ, Su YX, Zhang ... 6 (5): 773-785. doi:10.1210/mend.6.5.1603086. PMID 1603086. S2CID 25208340. Keaveney M, Klug J, Dawson MT, Nestor PV, Neilan JG ...
... flanking region of the Pigr gene contains a response element to glucocorticoids. This class of hormones increases the steady ... Cleavage occurs at the junction of the transmembrane region of the receptor and domain 5. pIgRs are capable of capturing IgA ... The quite long intracellular domain of the receptor, along with the transmembrane region, is responsible for the transduction ... Evidence for the involvement of multiple complementarity determining region (CDR)-like loops in receptor domain I". The Journal ...
... flanking region and structural organization". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1395 (1): 62 ... 42 (Database issue): D490-5. doi:10.1093/nar/gkt1178. PMC 3965031. PMID 24270786. "Glycoside Hydrolase Family 59". CAZypedia. ...
... flanking region of the gene". Genomics. 19 (1): 91-6. doi:10.1006/geno.1994.1017. PMID 8188248. Byrne JA, Smith PJ (1993). "The ... This gene may play a role in malignancies and disease that involve this region. This gene is oriented in a head-to-tail ... It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. ... Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, ...
... flanking region". Genomics. 19 (2): 369-72. doi:10.1006/geno.1994.1072. PMID 8188267. Sparkes RS, Lee RH, Shinohara T, et al. ( ... 2000). "A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region". ... doi:10.1016/S0021-9258(18)43955-5. PMID 7961975. Abe T, Kikuchi T, Shinohara T (1994). "The sequence of the human phosducin ...
... flanking region of the coagulation factor VII gene". J. Thromb. Haemost. 1 (6): 1220-7. doi:10.1046/j.1538-7836.2003.00227.x. ... 113 (5): 877-86. doi:10.1242/jcs.113.5.877. PMID 10671377. Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro ... 5 (12): 1301-10. doi:10.1091/mbc.5.12.1301. PMC 301159. PMID 7696711. Faulkner NE, Vig B, Echeverri CJ, et al. (1998). " ... U.S.A. 92 (5): 1634-8. Bibcode:1995PNAS...92.1634W. doi:10.1073/pnas.92.5.1634. PMC 42574. PMID 7878030. Garces JA, Clark IB, ...
... flanking region of the human corticotropin releasing hormone gene". DNA Sequence. 4 (3): 197-206. doi:10.3109/10425179309015632 ... "Structural analysis of the regulatory region of the human corticotropin releasing hormone gene". FEBS Letters. 267 (1): 1-5. ... 2 (5): 775-779. doi:10.1002/j.1460-2075.1983.tb01499.x. PMC 555184. PMID 6605851. Behan DP, Heinrichs SC, Troncoso JC, Liu XJ, ... 5 (2): 137-141. doi:10.1038/sj.mp.4000720. PMID 10822340. Saeed B, Fawcett M, Self C (February 2001). "Corticotropin-releasing ...
... flanking region and structural organization". Biochim. Biophys. Acta. 1395 (1): 62-67. doi:10.1016/S0167-4781(97)00140-1. PMID ... region". Hum. Mutat. 28 (7): 742. doi:10.1002/humu.9500. PMID 17579360. S2CID 1705020. Beier UH; Görögh T (2005). "Implications ... 5 (9): e12862. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624. GeneReviews/NCBI/NIH/UW entry on Krabbe disease ... 1998). "Human galactocerebrosidase gene: promoter analysis of the 5'- ...
... flanking region of the human follicle-stimulating hormone receptor gene". Molecular and Cellular Endocrinology. 102 (1-2): 93- ... Upon initial binding to the LRR region of FSHR, FSH reshapes its conformation to form a new pocket. FSHR then inserts its ... "Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor ... 8 (5): 413-21. doi:10.1093/humupd/8.5.413. PMID 12398222. Delbaere A, Smits G, Olatunbosun O, Pierson R, Vassart G, Costagliola ...
... flanking region for the human topoisomerase III gene". The Journal of Biological Chemistry. 273 (40): 26130-7. doi:10.1074/jbc. ... "Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse ... "Gene for topoisomerase III maps within the Smith-Magenis syndrome critical region: analysis of cell-cycle distribution and ... 12 (5): 713-28. doi:10.1101/gr.73702. PMC 186594. PMID 11997338. Wang Y, Lyu YL, Wang JC (Sep 2002). "Dual localization of ...
... flanking region of CYP3A5: comparative analysis with CYP3A4 and CYP3A7". Biochemical and Biophysical Research Communications. ... 4 (5): 247-59. doi:10.1097/00008571-199410000-00003. PMID 7894497. Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, ... 6 (5): 379-85. doi:10.1097/00008571-199610000-00001. PMID 8946469. Anttila S, Hukkanen J, Hakkola J, Stjernvall T, Beaune P, ... doi:10.1016/S0021-9258(18)81632-5. PMID 2732228. Schuetz JD, Molowa DT, Guzelian PS (November 1989). "Characterization of a ...
... flanking region of the human GIP receptor (GIPR) gene". Endocr. Res. 28 (4): 577. doi:10.1081/ERC-120016843. PMID 12530665. ... 2003). "Analysis of the putative promoter region of the GIP receptor gene (GIPR) in GIP-dependent Cushing's syndrome (CS)". ... 53 (5): 1326-1335. doi:10.2337/diabetes.53.5.1326. PMID 15111503. Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status ... doi:10.1016/0167-0115(96)00019-5. PMID 8795084. S2CID 42462407. N'Diaye N, Tremblay J, Hamet P, et al. (1998). "Adrenocortical ...
... flanking region of the transforming growth factor alpha gene". Mol. Endocrinol. 5 (12): 1955-63. doi:10.1210/mend-5-12-1955. ... 2 (5): 355-358. doi:10.1038/sj.mp.4000307. PMID 9322223. Ferrer, I.; Alcantara, S.; Ballabriga, J.; Olive, M.; Blanco, R.; ... 33 (5): 628-31. doi:10.1136/gut.33.5.628. PMC 1379291. PMID 1612477. Bean MF, Carr SA (1992). "Characterization of disulfide ... TGF-α has also been observed to be highly expressed in the suprachiasmatic nucleus (SCN) (5). This finding suggests a role for ...
... flanking region gene contains a "CAAT" consensus promoter sequence but no "TATA" sequence. The transcription start site is an ... 85 (1): 41-5. Bibcode:1988PNAS...85...41K. doi:10.1073/pnas.85.1.41. PMC 279477. PMID 3422424. Koike K, Urata Y, Koike M (Aug ... 284 (5): E855-62. doi:10.1152/ajpendo.00526.2002. PMID 12676647. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S ... There was an Alu family found in introns 2 and 8. The 5' ... and characterization of a full length-enriched and a 5'-end- ...
... flanking region". Mol. Endocrinol. 3 (9): 1448-54. doi:10.1210/mend-3-9-1448. PMID 2608068. Loric S, Egloff M, Domingo M, et al ... The gene localizes to a chromosomal region containing several closely related serine protease inhibitors (serpins). Transcortin ... 97 (1): E151-5. doi:10.1210/jc.2011-2022. PMID 22013108. Rosen MI, Shnider SM, Levinson G, Hughes (2002). Shnider and ... 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1-2): 149- ...