No I don't think it should, your plasma is just the fluid that your blood cells are in, there are some issues with plasma though such as the fact that the amount of solvent much match that of the blood cells, as if there is not enough then it will be hypotonic and cause your blood cells to take on to much water and go through hemolysis witch is basically the cell exploding, if the is to much solvent then it is hypertonic and will drain water from the cells and cause then to shrivel and become useless. However not very one needs the same so your plasma should still be use able