Adipose. Medical search. Frequent questions

In this study, we have investigated the protective effect of adipose-derived mesenchymal stem cells (ADSCs) and the role of epigallocatechin gallate (EGCG) in enhancing this effect in aging cerebral cortex of rats. (medsci.org)
Adipose tissue-derived mesenchymal stem cells (AD-MSC) show great potential to treat inflammatory and degradative processes in OA and have demonstrated paracrine effects in chondrocytes. (karger.com)
We designed a study to find theoretical evidence for the induction, movement, fusion, proliferation, and safety of human adipose mesenchymal stem cells (hADSCs) in intraocular application. (molvis.org)
Therefore, in this study, we assessed the ability of human adipose mesenchymal stem cells (hADSCs) to express the characteristics of ECs after induction in vitro to evaluate the theoretical feasibility of maintaining or restoring the function of ECs after intraocular application. (molvis.org)
Immortalized C57BL/6 Mouse Adipose-Derived Mesenchymal Stem Cells - 1 kit is backordered and will ship as soon as it is back in stock. (dnamethsoc.com)
The aim of this study was to compare the osteogenic potential of mesenchymal stem cells obtained from bone marrow (BM-MSC) with those extracted from adipose tissue (AT-MSC) of adult dogs. (scielo.br)

In obesity, adipose tissue is also implicated in the chronic release of pro-inflammatory markers known as adipokines, which are responsible for the development of metabolic syndrome, a constellation of diseases, including type 2 diabetes, cardiovascular disease and atherosclerosis. (wikipedia.org)
In obesity the inherent capacity of adipose tissue to store and sense nutrients is compromised, causing spillover of the intermediate lipid metabolites into circulation and resulting in their ectopic deposition in tissues not suitable for lipid storage, a phenomenon known as lipotoxicity. (frontiersin.org)
Upregulation of early and downregulation of terminal pathway complement genes in subcutaneous adipose tissue and adipocytes in acquired obesity. (nature.com)
Critical role of matrix metalloproteinase 14 in adipose tissue remodeling during obesity. (nature.com)
The aim of this study was to determine whether the mean size of fat cells in either visceral or subcutaneous adipose tissue has an impact on the metabolic and inflammatory profiles in morbid obesity. (nih.gov)
Hyperplasia (many small adipocytes) in both adipose regions may be protective against lipid as well as glucose/insulin abnormalities in obesity. (nih.gov)
Adipose tissue in obesity becomes refractory to suppression of fat mobilization by insulin, and also to the normal acute stimulatory effect of insulin on activation of lipoprotein lipase (involved in fat storage). (cambridge.org)
Here, we summarise the mechanisms contributing to adipose tissue (AT) plasticity and function including characteristics and cellular complexity of the various adipose depots and we discuss recent insights into AT origins, identification of adipose precursors, pathophysiological regulation of adipogenesis and its relation to WAT/BAT expandability in obesity and its associated comorbidities. (springer.com)
The 'adipose tissue expandability model' identifies the limited capacity and dysfunctionality of WAT, preventing its expansion and accommodation of surplus of energy, as key determinants for the onset and progression of obesity-associated metabolopathologies as a result of ectopic deposition of toxic lipid species in metabolic organs (i.e. muscle or liver [also known as lipotoxic insult]) [ 7 ]. (springer.com)
Remarkably, dietary selenium supplementation elevated facultative incorporation into UCP1, elevated energy expenditure through thermogenic adipose tissue, and protected against obesity. (nih.gov)
Excess adipose tissue, resulting in obesity, is currently one of the most serious threats to human health on a global level. (europa.eu)
For the present proposal we will test the hypothesis, that adipose tissue is one of the links between systemic inflammation causing insulin resistance in critically ill patients and low-grade inflammation causing insulin resistance in obesity. (europa.eu)
To test this obesity we will characterize adipose tissue as a secretory organ using interstitial fluid sampling techniques and advanced peptide analysis in critically ill patients and healthy controls. (europa.eu)
The circadian clock component NR1D1 (REVERBα) is considered a dominant regulator of lipid metabolism, with global Nr1d1 deletion driving dysregulation of white adipose tissue (WAT) lipogenesis and obesity. (elifesciences.org)
18 F -fluorodeoxyglucose positron emission tomography combined with computed tomography (FDG-PET/CT) is widely used as a standard method for evaluating human brown adipose tissue (BAT), a recognized therapeutic target of obesity. (spiedigitallibrary.org)
Inhibition of COX activity attenuated diet-induced UCP1 expression and increased energy efficiency and adipose tissue mass in obesity-resistant mice kept at thermoneutrality. (ku.dk)
Our results indicate that cyclooxygenase-dependent induction of UCP1 expression in white adipose tissues is important for diet-induced thermogenesis providing support for a surprising role of COX activity in the control of energy balance and obesity development. (ku.dk)
In this study, we observed the overexpression of SUMO-speci﫿c protease 2 (Senp2) in adipose tissues during obesity. (deepdyve.com)
Vitamin D accumulates in adipose tissue (AT), and vitamin D deficiency is frequent in obesity. (medscape.com)
The high prevalence of vitamin D deficiency in obese subjects [ 3 ] suggests that adipose tissue (AT) has a major role in the body distribution of vitamin D, but the causal relationship between obesity and low levels of circulating 25(OH)D has not been completely elucidated yet. (medscape.com)
Rare adipose disorders (RADs) masquerading as obesity. (medlineplus.gov)

In humans, adipose tissue is located: beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow), intermuscular (Muscular system) and in the breast (breast tissue). (wikipedia.org)
Adipose cell size (lipid per cell) was determined in three different subcutaneous and deep fat depots in each patient and the total number of adipose cells in the body estimated by division of total body fat by various combinations of the adipose cell sizes at six different sites. (jci.org)
A transcriptomic research revealed a rise in LOX manifestation in subcutaneous white adipose cells from obese topics, but its pathophysiological relevance continues to be unclear (Henegar et al. (exposed-skin-care.net)
Visceral Adipose Tissue (VAT) and subcutaneous Adipose Tissue (SAT) were defined by the Hologic APEX software used in the scan analysis. (cdc.gov)

Adipocytes, the key components of the adipose tissue, have unique ability to store excess energy in the form of triglycerides, sense systemic energy demands, and secrete factors (lipids, peptides, cytokines, and adipokines) to regulate other metabolic tissues. (frontiersin.org)
Notably, recent studies suggest that the accumulation of sphingolipids, namely ceramides and it's metabolites, play essential roles in the development of insulin resistance in tissues such as skeletal muscle, liver and, adipose tissue in obese rodents, and humans ( 6 - 20 ). (frontiersin.org)
In lipodystrophy there is insufficient adipose tissue to absorb the postprandial influx of fatty acids, so these fatty acids will again be directed to other tissues. (cambridge.org)
This view of the link between adipose tissue and insulin resistance emphasises the important role of adipose tissue in 'buffering' the daily influx of dietary fat entering the circulation and preventing excessive exposure of other tissues to this influx. (cambridge.org)
Oxidation of cysteine thiols by physiological reactive oxygen species (ROS) initiates thermogenesis in brown and beige adipose tissues. (nih.gov)
It is our goal to establish an ARC focused on understanding the relationship between metabolic disorders and Adipose Tissue Biology by studying adipose tissues from insulin sensitive and insulin resistant patients obtained during and after Bariatric Surgery. (bu.edu)
The levels of organochlorine residues in 40 samples of milk and 20 human adipose tissues from two locations in the northern of Côte d Ivoire were determined. (scialert.net)
Human breast milk samples (40 samples) and adipose tissues (20 samples) were collected from mothers (17 to 56 years old, average age 30) living in two different locations in the north of Côte d Ivoire (Korhogo and Sinématiali) from 2004 to 2007. (scialert.net)
Excess or insuf﫿cient lipid storage in generation of the intermediate species of diacylglycerol (DAG) adipose tissues would impair nutrient homeostasis, which is and monoacylglycerol (MAG) (Young and Zechner, 2013). (deepdyve.com)
Although less fat stor- adqcKO pose lipid storage in adipocyte-speci﫿c Senp2 knockout mice fed age was shown in Senp2 adipose tissues, the increased with high-fat diets (HFD). (deepdyve.com)
Therefore, adipocyte-speci﫿c remain in adipose tissues. (deepdyve.com)
The emergence of single- cell transcriptomics has rapidly transformed our understanding of the diverse array of cell types and cell states residing in adipose tissues and has provided insight into how transcriptional changes in individual cell types contribute to tissue plasticity. (bvsalud.org)
Here, we present a comprehensive overview of the cellular atlas of adipose tissues focusing on the biological insight gained from single- cell and single-nuclei transcriptomics of murine and human adipose tissues . (bvsalud.org)

A crucial role is played by inflammatory mediators, especially those deriving from the adipose tissue and the liver, which are involved in the cascade of inflammation, fibrosis and eventually tumorigenesis. (wjgnet.com)

Adipose tissue (also known as body fat, or simply fat) is a loose connective tissue composed mostly of adipocytes. (wikipedia.org)
In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages. (wikipedia.org)
Apart from adipocytes, which comprise the highest percentage of cells within adipose tissue, other cell types are present, collectively termed stromal vascular fraction (SVF) of cells. (wikipedia.org)
In humans the generation of fat cells (adipocytes) is a major factor behind the growth of adipose tissue during childhood. (europa.eu)
Adipose tissue-derived stem cells (ADSCs) have been characterized as having the ability to self-renew and differentiate into different connective tissue cells, including osteoblasts, adipocytes, chondrocytes and myocytes, under specific inductive stimuli ( 4 ). (spandidos-publications.com)

Besides, a role could be ascribed to molecules secreted by the visceral adipose tissue that can impact on barrier functions. (hindawi.com)
Visceral adipose tissue area, mass and volume of fat inside abdominal cavity were measured at the approximate interspace location of L4 and L5 vertebra. (cdc.gov)

The two types of adipose tissue are white adipose tissue (WAT), which stores energy, and brown adipose tissue (BAT), which generates body heat. (wikipedia.org)
In mammals, two types of adipose tissue have been observed: White Adipose Tissue, (WAT), which stores excess energy as triglycerides, and Brown Adipose Tissue (BAT), which dissipates stored energy as heat. (news-medical.net)

However, its main function is to be a reserve of lipids, which can be oxidised to meet the energy needs of the body and to protect it from excess glucose by storing triglycerides produced by the liver from sugars, although some evidence suggests that most lipid synthesis from carbohydrates occurs in the adipose tissue itself. (wikipedia.org)
Thus, in the postprandial period especially, there is an excess flux of circulating lipid metabolites that would normally have been 'absorbed' by adipose tissue. (cambridge.org)
Conversely, brown adipose tissue (BAT) and browning of WAT represent potential therapeutic approaches, since dysfunctional white adipocyte-induced lipid overspill can be halted by BAT/browning-mediated oxidative anti-lipotoxic effects. (springer.com)
There is also evidence that the deleterious effects mediated by dysfunctional white adipocyte-induced lipid overspill can be halted by the pro-oxidative anti-lipotoxic effects mediated by brown adipose tissue (BAT) activation. (springer.com)
Insuf﫿cient adipose lipid storage is asso- ciated with many pathological conditions including hyperlipidemia, insulin resistance, and type 2 diabetes. (deepdyve.com)
Adipocyte Senp2 de﫿ciency resulted in less adipose lipid storage accompanied by an ectopic fat accumulation and insulin resistance under high-fat diet feed- ing. (deepdyve.com)
These results revealed the crucial role of Senp2-Setdb1 axis in controlling adipose lipid storage. (deepdyve.com)
Under physiological conditions, the main- PPARγ mutation has been shown to link to familial partial lipody- tenance of normal adipose tissue mass is mainly the result of a strophy, a clinical disorder characterized by the loss of adipose balance of lipid storage and lipolysis (Bouchard et al. (deepdyve.com)
2010). Senp2 also regulates fatty acid metabolism in skeletal Downloaded from https://academic.oup.com/jmcb/article-abstract/10/3/258/4763638 by Ed 'DeepDyve' Gillespie user on 26 June 2018 Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1 j 259 muscle (Koo et al. (deepdyve.com)
Sample preparation steps for adipose tissue vary but, in general, involve a lipid extraction step followed by a clean-up procedure involving gel permeation chromatography (GPC) and/or Florisil column clean-up. (cdc.gov)

In morbidly obese women region-specific variations in mean adipocyte size are associated with metabolic complications but not systemic or adipose inflammation. (nih.gov)
Because adipose inflammation was linked to impaired arterial endothelial function, Dr. Gokce pointed out, "that may identify obese individuals at increased cardiovascular risk. (massagemag.com)
Adipose tissue inflammation appears to be a risk factor for the progression of chronic kidney disease (CKD), but the effect of CKD on adipose tissue inflammation is poorly understood. (mdpi.com)
The purpose of this study was to clarify the involvement of uremic toxins (indoxyl sulfate (IS), 3-indoleacetic acid, p-cresyl sulfate and kynurenic acid) on CKD-induced adipose tissue inflammation. (mdpi.com)
More recent studies suggest that inflammation in adipose tissue could be a key factor leading to these illnesses. (bu.edu)
In the present study, the potential of using exosomes isolated from adipose‑derived stem cells (ADSCs) as a therapeutic tool for reducing chronic inflammation and promoting chondrogenesis was investigated using patient‑derived primary cells. (spandidos-publications.com)

Adipose tissue is a key nutrient-sensing depot that regulates excess energy storage and consumption. (frontiersin.org)
Perivascular adipose tissue surrounds blood vessels and regulates cardiovascular physiology. (jove.com)

In this review, we intend to provide a perspective on ceramides and ceramide metabolites in the maintenance of adipose tissue homeostasis and how adipose tissue ceramides contribute to the development of metabolic diseases. (frontiersin.org)
White adipose tissue (WAT) has key metabolic and endocrine functions and plays a role in regulating energy homeostasis and insulin sensitivity. (springer.com)
However, the metabolic role and possible consequences of adipose tissue as a secretory organ in critically ill patients has not been investigated to date. (europa.eu)
BAPN also ameliorated the upsurge in collagen content material that was seen in adipose cells from obese pets and improved many metabolic guidelines C it ameliorated blood sugar and insulin amounts, reduced homeostasis model evaluation (HOMA) index and decreased plasma triglyceride amounts. (exposed-skin-care.net)
Consequently, our data offer proof that LOX takes on a pathologically relevant part in the metabolic dysfunction induced by weight problems and emphasise the eye of book pharmacological interventions that focus on adipose cells fibrosis and LOX activity for the medical management of the disease. (exposed-skin-care.net)
2008). Consequently, the purpose of this research was to explore the part of LOX activity in adipose cells remodelling and in the metabolic disruptions associated with weight problems. (exposed-skin-care.net)

This thesis focuses on assessing cell-material interactions between degradable 3D polymer scaffolds with different designs and adipose tissue-derived stem cells. (kth.se)
Adipose tissue (AT) represents a commonly used source of mesenchymal stem/stromal cells (MSCs) whose proregenerative potential has been widely investigated in multiple clinical trials worldwide. (mdpi.com)
According to our " Coherent Market Insights " newest study, the Adipose Derived Stem Cell Therapy Market is anticipated to grow at a promising CAGR by 2030. (digitaljournal.com)
Adipose Derived Stem Cell Therapy Market study focuses on key market players and investigates all important areas of the competitive landscape. (digitaljournal.com)
It also includes a growth forecast for the coming years, as well as a critical evaluation of 𝐦𝐚𝐫𝐤𝐞𝐭 𝐝𝐲𝐧𝐚𝐦𝐢𝐜𝐬, 𝐦𝐚𝐫𝐤𝐞𝐭 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐟𝐚𝐜𝐭𝐨𝐫𝐬, 𝐜𝐮𝐫𝐫𝐞𝐧𝐭 𝐭𝐫𝐞𝐧𝐝𝐬 in the Adipose Derived Stem Cell Therapy Market, constraints and obstacles. (digitaljournal.com)
The Adipose Derived Stem Cell Therapy Market research study focuses on worldwide values from the previous year as well as a possible projection for 2030. (digitaljournal.com)
Both primary and secondary data sources have been used in the Adipose Derived Stem Cell Therapy Market research report. (digitaljournal.com)
In total, 1-10% of nucleated cells in adipose tissue are ADSCs, whereas only 0.0001-0.01% of nucleated cells in bone marrow are stem cells ( 5 ). (spandidos-publications.com)
The adipose tissue is an important reservoir of adult stem cells which have capacity of differentiating in osteoblasts with potential implication in reaching bone regeneration. (bvsalud.org)

In an obese person, excess adipose tissue hanging downward from the abdomen is referred to as a panniculus. (wikipedia.org)
Any plausible explanation for the link between excess adipose tissue and insulin resistance needs to be able to account for this observation. (cambridge.org)

Marrow Adipose Tissue: is a unique fat depot in the bone marrow and has a close relationship with hematopoiesis and bone homeostasis. (labroots.com)

Relative abundance of organochlorine pesticides and polychlorinated biphenyls in adipose tissue and serum of women in Long Island, New York. (aacrjournals.org)
It is important to know whether adipose tissue used by some investigators and serum assays used by others can provide comparable information on body burden. (aacrjournals.org)
Concentrations of seven OCPs or their breakdown products as well as 14 PCB congeners were measured in the adipose tissue and serum of 293 women enrolled as controls in a case-control study of environmental factors for breast cancer in Long Island, New York, a high-risk region. (aacrjournals.org)
1,1-Dichloro-2,2-di(4-chlorophenyl)ethylene comprised 77% of total pesticide residues in adipose and 71% in serum. (aacrjournals.org)
All adipose-serum correlations for pesticides and most PCBs were statistically significant. (aacrjournals.org)
Either serum or adipose OCP/PCB levels of a variety of environmental organochlorine compounds may serve as useful biomarkers of body burden. (aacrjournals.org)
[ 5 , 6 ] An alternative hypothesis considers low serum 25(OH)D in obese as a result of volumetric dilution of vitamin D in the large adipose stores. (medscape.com)

Measurements were made of the activities of enzymes of glycerolipid synthesis in homogenates of interscapular brown adipose tissue. (bl.uk)
CONCLUSIONS/SIGNIFICANCE: Our findings provide evidence that induction of UCP1 expression in white adipose tissue, but not in classic interscapular brown adipose tissue is dependent on cyclooxygenase activity. (ku.dk)

Marrow adipose tissue exhibits a considerable adaptive plasticity and secretes a broad spectrum of hormones. (labroots.com)
Adipose tissue exhibits remarkable plasticity with capacity to change in size and cellular composition under physiological and pathophysiological conditions. (bvsalud.org)

which produces hormones), or changes in the deposition and breakdown of fat (adipose tissue metabolism). (medlineplus.gov)

The researchers found that 50 of the subjects had an inflamed adipose phenotype characterized by tissue macrophage accumulation in crown-like structures. (massagemag.com)
Loss of the LD-associated Adipose Triglyceride Lipase (ATGL) disrupts both actin bundle formation and cortical actin integrity, an unusual phenotype also seen when Pxt, the enzyme responsible for prostaglandin (PG) synthesis, is missing. (biorxiv.org)

Regarding adipose tissue, this trend was also observed, except for DDT and its metabolites whose values were far below the MRL. (scialert.net)

In order to characterize the chicken HSL enzyme, it was purified 3500 fold from a chicken adipose tissue homogenate using pH 5.2 precipitation and anion-exchange chromatography. (lu.se)

Lipodystrophy, lack of adipose tissue, is also associated with insulin resistance. (cambridge.org)
Initial studies of bariatric surgery patients by the Ruderman laboratory established (1) that they could be subdivided into insulin resistant (75%) and insulin sensitive (25%) subgroups and (2) that these subgroups were distinguished by differences in AMPK activity, oxidative stress and the expression of inflammatory, mitochondrial and other genes in their adipose tissue. (bu.edu)
Also, in these pets, BAPN ameliorates the disruptions in the adipose cells manifestation of adiponectin, blood sugar transporter 4 (GLUT4), buy 76584-70-8 suppressor of cytokine signaling 3 (SOCS3) and dipeptidyl peptidase 4, all protein mixed up in control of insulin level of sensitivity. (exposed-skin-care.net)

Adipose tissue samples revealed the presence of polychlorinated biphenyl (PCB), Hexachlorobiphenyl (HCB) in addition to pesticides which are found in the milk Average concentrations of organochlorine pesticides in milk matrix were above the Maximum Residue Limits (MRL) of WHO. (scialert.net)

The cellular character of the adipose tissue of 21 nonobese and 78 obese patients has been examined. (jci.org)

Adipose tissue contains many small blood vessels. (wikipedia.org)

Brown adipose tissue (BAT) is known to play a critical role in cold-induced nonshivering thermogenesis (CIT) to maintain body temperature. (spiedigitallibrary.org)

The current proposal aims to determine the dynamics of human adipose tissue maintenance and investigate any differences in regulation of the fat mass in lean and obese individuals. (europa.eu)
The goal of this protocol is to test the ability of progenitor cells derived from human perivascular adipose tissue to differentiate into multiple cell lineages. (jove.com)
This protocol is used to answer key questions related to the function of human adipose progenitors in the vascular microenvironment. (jove.com)
Obtain a 500 milligram piece of Human Perivascular Adipose Tissue or PVAT from the operating room as described in the text protocol. (jove.com)
Biopsy of adipose tissue identified human adenovirus 36 (Adv 36) DNA. (cdc.gov)
HSL from chicken adipose tissue exhibits remarkable activation upon phosphorylation with cAMP-dependent protein kinase (cAMP-PK) compared to HSL from rat and human adipose tissue. (lu.se)
The writers demonstrate that LOX may be the primary lysyl oxidase isoenzyme indicated in Rabbit polyclonal to ZFP161 human being adipose cells and that it's upregulated in examples from both obese people and rats given a high-fat diet plan. (exposed-skin-care.net)

Viral DNA was isolated from brain, lung, liver, muscle, and adipose tissue of monkeys 7 months after initial infection, long after the active virus has disappeared from blood and feces ( 3 ). (cdc.gov)
The immune system participates in this process with disturbances of the cells constituting both the innate and the adaptive immune systems that have been reported in different organs, such as in the liver and in the adipose tissue, in clinical and preclinical studies. (wjgnet.com)

Linda Evangelista Says She Has 'Paradoxical Adipose Hyperplasia' from CoolSculpting: a Doctor. (yahoo.com)
Linda Evangelista is opening up, to shed her shame, about her paradoxical adipose hyperplasia , a. (yahoo.com)

This knowledge can be used to engineer 3D scaffolds with adequate physio-chemical and mechanical properties along with an appropriate design that augments adipose tissue regeneration. (kth.se)

NEW YORK (Reuters Health) - Certain obese people demonstrate potentially harmful proinflammatory changes in their adipose tissue, researchers report in the September issue of Arteriosclerosis, Thrombosis, and Vascular Biology. (massagemag.com)
Outcomes This research analyses the part of LOX in adipose cells remodelling through the use of three experimental systems: adipose cells examples from obese people that had been known for bariatric medical procedures (weight loss operation), an pet style of diet-induced weight problems and cell-based research. (exposed-skin-care.net)

Adipose tissue is found in specific locations, which are referred to as adipose depots. (wikipedia.org)
Adipose depots in different parts of the body have different biochemical profiles. (wikipedia.org)
Mice have eight major adipose depots, four of which are within the abdominal cavity. (wikipedia.org)
The two superficial depots are the paired inguinal depots, which are found anterior to the upper segment of the hind limbs (underneath the skin) and the subscapular depots, paired medial mixtures of brown adipose tissue adjacent to regions of white adipose tissue, which are found under the skin between the dorsal crests of the scapulae. (wikipedia.org)

Steers were fed a red clover silage-based diet with or without flaxseed to evaluate over time the effects of flaxseed supplementation on erythrocytes (ERC) trans(t) 18:1 isomers composition and their relationships to adipose tissue and muscle t 18:1 profiles at slaughter. (bioone.org)
Indeed, while the average of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT), predominant specie and its isomers in adipose tissue was 10.02 mg kg -1 in countryside and 6.93 mg kg -1 in the city, it was respectively 0.013 and 0.019 mg kg -1 in milk. (scialert.net)

Recent studies have indicated that adipose tissue plays a major role in the secretion of inflammatory factors, which have been called adipo-cytokines or adipokines. (europa.eu)
Objectives (1) To compare spontaneous and stimuli-induced adipocytokine secretion by articular adipose tissue (AAT) and synovial membrane (SM) explants obtained from patients with rheumatoid arthritis (RA). (bmj.com)

A pericellular collagenase directs the 3-dimensional development of white adipose tissue. (nature.com)
AD-MSC were isolated by collagenase treatment from adipose tissue from healthy individuals subjected to abdominal lipectomy surgery. (karger.com)

Bioaccumulation - accumulation in adipose tissue of aquatic organisms. (janusinfo.se)

To evaluate the immunoexpression of BMP-2 protein on the bone repairing of critical size defects (CSD) surgically created in rat calvaria and treated by autogenous macerated adipose tissue. (bvsalud.org)

Lately, fibrosis continues to be recognised as an essential participant in adipose cells dysfunction in weight problems. (exposed-skin-care.net)
In obese rats, the inhibition of LOX activity through -aminopropionitrile (BAPN, a particular inhibitor of LOX activity) decreases adipose cells fibrosis, partly corrects the adipocyte-size distribution design (moving it toward smaller sized sizes) and attenuates the upsurge in bodyweight and extra fat mass. (exposed-skin-care.net)
In group AT, both at 7 and 90 post-operative days, the main healing type was the presence of dense conjunctive tissue exhibiting bundles of collagen fibers disposed in beams permeating the remaining adipose tissue with rare heterotopic bone formation associated to fibrosis and different types of tissue necrosis. (bvsalud.org)

The use of PGE(2) receptor antagonists implicated EP(4) as a main PGE(2) receptor, and injection of the stable PGE(2) analog (EP(3/4) agonist) 16,16 dm PGE(2) induced UCP1 expression in inguinal white adipose tissue. (ku.dk)

Recently, adipose tissue has been shown to synthesise and release highly bioactive substances: classical adipokines (eg, leptin, adiponectin) and various proinflammatory factors such as cytokines, chemokines, growth factors and complement components. (bmj.com)

One tissue of great interest and significant clinical relevance is adipose tissue. (europa.eu)

It is widely accepted that members of the complement pathway are expressed at high levels in white adipose tissue (WAT). (nature.com)

Adipose tissue - more specifically brown adipose tissue - was first identified by the Swiss naturalist Conrad Gessner in 1551. (wikipedia.org)
These findings are relevant to signals that drive early events in mitochondriogenesis and cell proliferation in brown adipose tissue on exposure to cold. (bl.uk)

In soft tissue defects that arise due to trauma, tumor resections and complex burns, a significant loss in adipose tissue remains a considerable challenge due to the insufficient regenerative capacity of the tissue. (kth.se)

White adipose tissue (WAT) plays a key homeostatic role, not only by ensuring efficient energy storage but also by its quick mobilisation (lipids) to ensure peripheral demands. (springer.com)
Furthermore, in white adipose cells from obese pets, BAPN avoided the downregulation of adiponectin and blood sugar transporter 4 (GLUT4), aswell as the upsurge in suppressor of cytokine signaling 3 (SOCS3) and dipeptidyl peptidase 4 (DPP4) amounts, triggered from the HFD. (exposed-skin-care.net)

Nevertheless, its contribution to adipose cells dysfunction in weight problems is not clearly established. (exposed-skin-care.net)

Far from being hormonally inert, adipose tissue has, in recent years, been recognized as a major endocrine organ, as it produces hormones such as leptin, estrogen, resistin, and cytokines (especially TNFα). (wikipedia.org)
4 5 Adipose tissue is an active endocrine organ, heterogeneous with respect to embryonic origin, body distribution and function. (bmj.com)

Anatomy31

Organisms12

Diseases27

Chemicals and Drugs91

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Psychiatry and Psychology2

Phenomena and Processes51

Disciplines and Occupations1

Technology, Industry, Agriculture5

Information Science2

Health Care4

Geographicals1

Mesenchymal stem6

Obesity21

Subcutaneous4

Tissues13

Deriving from the adipose tissue1

Adipocytes5

Visceral2

Types of adipose tissue2

Lipid10

Inflammation6

Regulates2

Metabolic6

Stem9

Excess2

Homeostasis1

Serum7

Interscapular brown2

Plasticity2

Metabolism1

Phenotype2

Metabolites1

Characterize1

Insulin3

Organochlorine Pesticides1

Cellular1

Blood vessels1

Thermogenesis1

Human7

Liver2

Hyperplasia2

Regeneration1

Obese people2

Depots4

Isomers2

Secretion2

Collagenase2

Accumulation1

Protein1

Fibrosis3

UCP11

Proinflammatory1

Clinical1

Pathway1

Brown2

Insufficient1

White2

Dysfunction1

Endocrine2