Adrenocortical tumors adrenocortical carcinoma. Medical search. Frequent questions

However, three additional histologies (thyroid carcinoma, melanoma, and testicular cancer) with incidences of more than 2 cases per 1 million people were also included in the very rare group because there is a lack of knowledge and expertise in the management of these tumors. (cancer.gov)
Among the cancers we treat are germ cell tumors of the brain , melanoma , and nasopharyngeal, adrenocortical, and thyroid carcinomas. (childrenshospital.org)
Preclinical studies show that mebendazole notably impedes the growth of malignant and metastatic tumors such as osteosarcoma and soft tissue sarcoma, melanoma, carcinoma (lung, colorectal, breast, ovarian, hepatocellular and adrenocortical), acute myeloid leukaemia, glioblastoma multiforme and meduloblastoma. (biomedical.pl)
gland carcinomas, paranasal sinus cancers and melanoma of miology and prevention. (who.int)
Other common sources of cardiac metastases include breast and kidney carcinoma, melanoma, and lymphoma. (msdmanuals.com)

Hereditary paraganglioma-pheochromocytoma - an inherited condition causing different types of tumors that make adrenaline and other hormones. (medlineplus.gov)
Difficulties encountered were overhanging nature of tumor, close proximity to renal vessels, desmoplastic reaction in pheochromocytoma and intact specimen retrieval. (sages.org)
The diagnosis confirmed on histopathology was pheochromocytoma (n=26), paraganglioma (n=4), adenomyolipoma (n=7), Cushing's disease (n=4), schwannoma (n=1), tuberculosis (n=1), carcinoma (n=2) and adrenocortical sarcoma (n=1). (sages.org)
Because of its nonenhanced CT attenuation of less than or equal to 10 HU, a lipid-rich adrenal adenoma may be mimicked by a benign adrenal cyst, or it may be mimicked by a tumor with central cystic and/or necrotic change such as ACC, pheochromocytoma, or metastasis. (ctisus.com)
Pheochromocytoma is a rare neuroendocrine tumor of the adrenal medulla. (ctisus.com)
More recent data have shown that these values are not as specific for adenoma as previously believed, since other adrenal tumors such as pheochromocytoma, hypervascular metastases, and ACC also can meet these washout thresholds. (ctisus.com)
Herein we selected a Mendelian genetics form of familial cancer such as hereditary tumor syndromic endocrine neoplasias caused by highly penetrant germline mutations leading to pheochromocytoma-paraganglioma syndromes. (intechopen.com)
The common major pathologic entities of the adrenal gland that require surgical intervention are primary hyperaldosteronism (ie, Conn syndrome , see the second image below), Cushing syndrome , pheochromocytoma , neuroblastoma , and adrenocortical carcinoma . (medscape.com)
While pheochromocytoma follows the "rule of 10s," with only 10% of cases involving malignant tumors, 50% of cases of paraganglionomas have reported malignancies. (medscape.com)

This is a neuroendocrine tumor that affects the medulla. (medicalnewstoday.com)
We provide a specialized, team approach to treating neuroendocrine tumors, also known as NETs. (uchicagomedicine.org)
Pheochromocytomas are a type of neuroendocrine tumor . (uchicagomedicine.org)
These neuroendocrine tumors can be similar to pheochromocytomas but form elsewhere in the body. (uchicagomedicine.org)
A single-institution retrospective review identified 45 cases of neuroendocrine (carcinoid) tumors in children and adolescents between 2003 and 2016. (oncolink.org)
Most neuroendocrine tumors of the appendix are discovered incidentally at the time of appendectomy, and are small, low-grade, localized tumors. (oncolink.org)
In adults, it has been accepted practice to remove the entire right colon in patients with large neuroendocrine tumors of the appendix (>2 cm in diameter) or with tumors that have spread to the lymph nodes. (oncolink.org)
Study results suggest that appendectomy alone is sufficient treatment for pediatric appendiceal neuroendocrine tumors regardless of size, position, histology, or nodal or mesenteric involvement and that right hemicolectomy is unnecessary in children. (oncolink.org)
The Italian Tumori Rari in Etá Pediatrica project performed a prospective registry study that evaluated 113 patients with appendiceal neuroendocrine tumors. (oncolink.org)
The study concluded that appendectomy alone should be considered curative for most cases of appendiceal neuroendocrine tumors. (oncolink.org)
A French multicenter study of children younger than 18 years with neuroendocrine tumors of the appendix was carried out by surveying pediatric surgeons from 1988 to 2012. (oncolink.org)
The investigator's recommendation was that appendectomy alone is sufficient treatment for neuroendocrine tumors of the appendix. (oncolink.org)
A systematic review and meta-analysis of 38 studies of appendiceal neuroendocrine tumors identified 958 cases with a mean age at presentation of 11.6 years. (oncolink.org)
Cardio-Metabolic Indices and Metabolic Syndrome as Predictors of Clinical Severity of Gastroenteropancreatic Neuroendocrine Tumors. (ukw.de)
Pancreatic neuroendocrine tumor (PNET) (formerly named: Endocrine carcinoma of pancreas and digestive tract. (sncrf.org)
Neuroendocrine carcinoma including carcinoid of the lung (closed to accrual 12/19/2017) 24. (sncrf.org)

Adrenocortical carcinoma (ACC) has a poor prognosis with significant unmet clinical need due to late diagnosis, high rates of recurrence/metastasis and poor response to conventional treatment. (oncotarget.com)
Adrenocortical carcinoma (ACC) (also known as adrenal cortical carcinoma) is a rare malignancy with a poor prognosis, affecting 1-2 people per million per year year. (medscape.com)
Background: Molecular classification is important for diagnosis and prognosis of adrenocortical tumors (ACT). (endocrine-abstracts.org)
Transcriptome profiles separate benign ACT ( C2 cluster) from carcinomas (ACC) and identify two groups of ACC, C1A ( steroid and proliferation signatures) and C1B ( immune signature), of poor and better prognosis respectively. (endocrine-abstracts.org)
Background: Adrenocortical cancer (ACC) is an aggressive tumor with heterogeneous prognosis. (endocrine-abstracts.org)
Adrenocortical carcinoma (ACC) is a rare disease associated with a poor prognosis. (cancerindex.org)
Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor, with a poor prognosis and median survival of 3-4 years. (endocrine-abstracts.org)
Tumors with anaplastic histology usually have somatic mutation of TP53 and inferior prognosis compared to tumors with favorable histology [ Ooms et al 2016 , Daw et al 2020 ]. (nih.gov)
The establishment of diagnostic criteria is of great significance for prognosis of tumors. (bvsalud.org)
Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone-producing tumor with variable prognosis. (bvsalud.org)

Solid tumors account for approximately 40 percent of pediatric cancers and 68 percent of adolescent and young adult cancers. (cookchildrens.org)
The treatment of solid tumors may require a range of therapies, including surgery, radiation therapy, chemotherapy, stem cell therapy, biologic or targeted therapies, or a combination of these treatment modalities. (cookchildrens.org)
In treating pediatric Solid Tumors, our goal is to provide family-centered care utilizing the most advanced treatment, superior research and family preference to obtain the best chances for cures. (cookchildrens.org)
Even though developed for AML patients, our pan-cancer analyses demonstrate a wider application of the IPRP signature for prognostic prediction and analysis of tumor-immune interplay also in multiple solid tumors. (nature.com)
The goal if this clinical research study is to determine the maximum tolerated dose (MTD) and/or recommended dose and schedule for the daily oral administration of cabozantinib in subjects with solid tumors when taken in combination with Atezolizumab. (mdanderson.org)

Epithelial tumors of nasal cavity, sinuses, nasopharynx: A) Squamous cell carcinoma with variants of nasal cavity, sinuses, and nasopharynx and trachea (excluding laryngeal, nasopharyngeal cancer [NPC], and squamous cell carcinoma of the head and neck [SCCHN]) B) Adenocarcinoma and variants of nasal cavity, sinuses, and nasopharynx (closed to accrual 07/27/2018) 2. (sncrf.org)

Hepatocellular adenoma (HCA), also called hepatic adenoma, is an uncommon benign solid liver tumor. (medscape.com)
The top 14 hub genes were subsequently confirmed by reverse transcription‑quantitative polymerase chain reaction in ACC and adrenocortical adenoma samples. (cancerindex.org)
Adrenal adenoma is the most common benign adrenal tumor that arises from the cortex, whereas adrenocortical carcinoma (ACC) is a rare malignant tumor of the cortex. (ctisus.com)
A "tumour trifecta:" myelolipomata arising within an adrenocortical adenoma ipsilateral to a synchronous clear cell renal cell carcinoma. (mcmaster.ca)
Tumors of the adrenal cortex are reported in 2% of all autopsies, with the most common lesion being a benign adenoma (see the first image below). (medscape.com)

The National Comprehensive Cancer Network (NCCN) Soft Tissue Sarcoma Panel specifically identifies Li-Fraumeni syndrome and familial adenomatous polyposis (FAP) as genetic cancer syndromes with a predisposition for the development of STS, along with Carney-Stratakis syndrome, which is associated with gastrointestinal stromal tumors (GISTs) and paragangliomas. (medscape.com)

A Phase II Study to Evaluate the Effects of Cabozantinib in Patients with Unresectable/Metastatic Adrenocortical Carcinoma. (mdanderson.org)

Treatment for adrenal tumors will vary depending on the type of tumor and other factors. (uchicagomedicine.org)

Treatments for rare tumors are based on the type of tumor, the child's age, overall health, and medical history, location and size of the tumor, the extent of disease, and the doctor's expectations for how the tumor will behave. (childrenshospital.org)
There may be several other symptoms depending on factors, such as the type of tumor and the rate of its growth. (medicinenet.com)

The prevalence of bilateral involvement is higher in individuals with a predisposition to Wilms tumor than in those without a genetic predisposition (see Mechanisms of Predisposition to Wilms Tumor ), but unilateral, unifocal Wilms tumor does not preclude an underlying germline or epigenetic cause. (nih.gov)
In 10%-15% of individuals with Wilms tumor, the cause is considered to be a germline pathogenic variant or an epigenetic alteration occurring early during embryogenesis [ Mahamdallie et al 2019 ]. (nih.gov)
Multiple endocrine neoplasia syndrome type 1 (MEN-1), loss-of-function germline mutations in the tumor suppressor gene MEN1 increase the risk of developing pituitary, parathyroid and pancreatic islet tumors, and less commonly thymic carcinoids, lipomas and benign adrenocortical tumors. (intechopen.com)
In the case of multiple endocrine neoplasia type 2 (MEN 2), gain-of-function germline mutations clustered in specific codons of the RET proto-oncogene increase the risk of developing medullary thyroid carcinoma (MTC), phaeochromocytoma and parathyroid tumors. (intechopen.com)
Adrenocortical carcinoma (ACC): When and why should we consider germline testing? (cdc.gov)

Squamous cell carcinoma with variants of GI tract (stomach small intestine, colon, rectum, pancreas) (closed to accrual 10/17/2018) 7. (sncrf.org)
Squamous cell carcinoma variants of the genitourinary (GU) system 19. (sncrf.org)
This guideline covers diagnosing and managing bladder cancer in people 18 and above referred from primary care with suspected bladder cancer, and those with newly diagnosed or recurrent bladder (urothelial carcinoma, adenocarcinoma, squamous-cell carcinoma or small-cell carcinoma) or urethral cancer. (bvsalud.org)

Children who are treated through our Rare Tumors Program benefit from the work of our basic and clinical researchers, who are striving to understand the scientific causes of rare cancers, which results in the introduction of new treatment options. (childrenshospital.org)
Clinical trials have shown that patients with prostate, lung, and basal cell carcinoma have benefited from treatment with itraconazole, and there are additional reports of activity in leukaemia, ovarian, breast, and pancreatic cancers. (biomedical.pl)

Most tumors, or growths, on the adrenal glands are not cancerous. (uchicagomedicine.org)
These rare tumors begin in the medulla section of the adrenal glands. (uchicagomedicine.org)
Metastases to the adrenal glands are the most common malignant adrenal tumors. (ctisus.com)
However, many adrenal glands are removed en bloc as part of a radical nephrectomy for renal cell carcinoma . (medscape.com)

Replacing tumor suppressor microRNAs (miRNAs) offer a novel therapy, however systemic delivery remains challenging. (oncotarget.com)
This gene, often called a tumor suppressor gene, cannot protect cells from becoming cancerous when it isn't working properly. (choa.org)
The genetic changes that cause this syndrome are found in the DICER1 gene, a tumor suppressor gene. (choa.org)

One patient (adrenocortical sarcoma) died of metastasis 3 months after surgery. (sages.org)

This may include the use of new biologic agents that target specific mutations in these tumors. (childrenshospital.org)
Cancer is a complex genetic disease caused by abnormal alteration (mutations) in DNA sequences that leads to dyregulation of normal cellular processes thereby driving tumor growth. (intechopen.com)
Somatic mutations in adrenocortical carcinoma with hyperaldosteronism. (cdc.gov)

The incidence of primary malignant bone tumors is low, and clinical cognition is insufficient. (bvsalud.org)

Some tumors may become cancerous. (medlineplus.gov)
When a tumor is cancerous, our world-class cancer experts, including medical oncologists and radiation oncologists, are brought onto the team. (uchicagomedicine.org)
This is the most common type of cancerous adrenal tumor and it can be aggressive. (uchicagomedicine.org)
A small percentage of these tumors are cancerous. (uchicagomedicine.org)
The Rare Tumors Program at Dana-Farber/Boston Children's Cancer and Blood Disorders Center provides care for uncommon cancerous conditions. (childrenshospital.org)
These tumors may be noncancerous/benign or cancerous/ malignant . (medicinenet.com)

Introduction: Primary bilateral macronodular adrenal hyperplasia (PBMAH) are benign adrenocortical disease responsible for benign tumors and cortisol autonomous secretion. (endocrine-abstracts.org)
Adenohypophyseal proliferation was classified as hyperplasia (n = 40) if ≤2 mm diameter with intact reticulin network, as microadenoma (n = 22) for 1-5 mm homogeneous nodules with lost reticulin network, or as macroadenoma (n = 17) for larger tumors. (unboundmedicine.com)
Both HAC and adrenocortical hyperplasia showed a positive trend with the degree of adenohypophyseal proliferation. (unboundmedicine.com)
The association of adrenocortical hyperplasia with HAC was not significant (P = .077). (unboundmedicine.com)
Overview of Multiple Endocrine Neoplasias (MEN) The multiple endocrine neoplasia (MEN) syndromes comprise 4 genetically distinct familial diseases involving adenomatous hyperplasia and malignant tumors in several endocrine glands. (msdmanuals.com)

Not all individuals with a diagnosis of DICER1 syndrome will develop tumors or cancer. (choa.org)
Their conclusion confirmed the first hospital's diagnosis of stage IV adrenocortical carcinoma. (burzynskipatientgroup.org)
001) and adrenocortical histologic diagnosis (P = .025). (unboundmedicine.com)
A definitive diagnosis of Wilms tumor can be made only on histologic assessment of the tumor. (nih.gov)
Pitfalls and progress in adrenocortical carcinoma diagnosis: the utility of a multidisciplinary approach, immunohistochemistry and genomics. (cdc.gov)

Some types of adrenal tumors cause high blood pressure, diabetes, Cushing's syndrome and other conditions. (uchicagomedicine.org)
We also specialize in diagnosing and treating rare types of adrenal tumors, including those linked to inherited disorders. (uchicagomedicine.org)

This research is a continuation of the work I led in Sydney which identified tumour and blood markers and resulted in a phase I clinical trial of microRNA replacement therapy (NCT 02369198). (otago.ac.nz)
Children with progressive or recurrent tumors may be eligible for a number of experimental therapies through this group or through one of our independent clinical trials. (childrenshospital.org)
In each case, the clinical presentation, location of the tumour, and the outcome for the patient were studied. (bmj.com)
Compared with solid tumor sampling, the bone marrow or peripheral blood of leukemia patients is easier to access, and therefore an accurate and practical prognostic signature for leukemia patients has potential for more direct clinical application. (nature.com)
Briefly describe the clinical characteristics of Wilms tumor. (nih.gov)
Clinical features of Wilms tumor predisposition syndromes (See Table 1 and Table 2 . (nih.gov)
ENSAT registry-based randomized clinical trials for adrenocortical carcinoma. (ukw.de)
The goal of this clinical research study is to learn if mitotane alone or in combination with cisplatin and etoposide can help to control adrenocortical carcinoma (ACC) in patients who are at a high risk of having the disease return after surgery. (mdanderson.org)
The goal of this clinical research study is to learn if cabozantinib can help to control unresectable (cannot be removed with surgery) or metastatic (has spread) adrenocortical carcinomas. (mdanderson.org)
National Comprehensive Cancer Network (NCCN) regularly publishes "Clinical Practice Guidelines for Bone Tumors" to summ. (bvsalud.org)

Adrenal carcinomas arise from the adrenal cortex and are bilateral in up to 10% of patients. (medscape.com)
42 patients underwent LA (n = 46) for large adrenal tumors (bilateral - 4 patients). (sages.org)
Approximately 5%-10% of individuals with Wilms tumor have bilateral or multicentric tumors. (nih.gov)

Genomic and sequence variants of protein kinase A regulatory subunit type 1beta (PRKAR1B) in patients with adrenocortical disease and Cushing syndrome. (ukw.de)

Rare pancreatic tumors including acinar cell carcinoma, mucinous cystadenocarcinoma or serous cystadenocarcinoma. (sncrf.org)

Also known as adrenal cortex tumors, these growths are usually benign but can cause an overproduction of cortisol, aldosterone or other hormones. (uchicagomedicine.org)

Approximately 50-80% are functional tumors, with most causing Cushing syndrome . (medscape.com)

Not Otherwise Categorized (NOC) Rare Tumors [To obtain permission to enroll in the NOC cohort, contact: [email protected]] (closed to accrual 03/15/2019) 34. (sncrf.org)

If a benign tumor is painful or interferes with hearing, surgical removal of the tumor may be necessary. (health32.com)
At the University of Chicago Medicine, our nationally respected endocrinologists and endocrine surgeons collaborate to identify the best way to treat benign adrenal tumors, using the most advanced medical and surgical approaches. (uchicagomedicine.org)
Research is essential to identify new markers that could better distinguish patients at higher risk of disease recurrence after surgical removal of the primary tumour. (amend.org.uk)

Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular sex cord cancer B) Non seminomatous tumor C) Teratoma with malignant transformation (closed to accrual) 17. (sncrf.org)

Literature seems markedly silent on retrieval of larger tumors. (sages.org)

Ports were standard but modified in some cases due to large size of the tumor. (sages.org)

After surgery, pathology tests confirmed that the abdominal mass was adrenocortical carcinoma and the lesions were metastasis from the original tumor. (burzynskipatientgroup.org)
In general, neoplastic lesions of the adrenal gland may be classified with the tumor, node, metastases (TNM) staging system. (medscape.com)

What Is the Optimal Duration of Adjuvant Mitotane Therapy in Adrenocortical Carcinoma? (ukw.de)

Adrenocortical carcinoma can be seen in familial syndromes such as multiple endocrine neoplasia type 1 (MEN-1), Li-Fraumeni syndrome , Beckwith-Wiedemann syndrome , and Carney complex . (medscape.com)
DICER1 syndrome, also known as DICER1-pleuropulmonary blastoma familial tumor predisposition syndrome, is a condition in which an individual is born with genetic changes that predispose him or her to develop benign and malignant tumors during childhood, through adolescence and, rarely, as an adult. (choa.org)

A higher risk of death was associated with increasing age, poorly differentiated tumors, involved margins, and nodal or distant metastases. (medscape.com)

Comparative Genomic Landscape of Urothelial Carcinoma of the Bladder Among Patients of East and South Asian Genomic Ancestry. (moffitt.org)

Tumors with invasion of adjacent organs were excluded. (sages.org)

The World Health Organization classification system for tumors of the soft tissue and bone incorporates detailed cytogenetic and molecular data into the classifications. (medscape.com)
Targeted molecular analysis in adrenocortical carcinomas: a strategy towards improved personalized prognostication. (cdc.gov)

Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03/30/2018) 14. (sncrf.org)

Adenoid cystic carcinoma (closed to accrual 02/06/2018) 35. (sncrf.org)

A detailed hormonal workup is also recommended to identify potential autonomous excess of glucocorticoids, sex hormones, mineralocorticoids, and adrenocortical steroid hormone precursors. (medscape.com)
But even benign tumors may cause the over-production of catecholamine hormones (epinephrine and norepinephrine), which can raise blood pressure and cause other problems. (uchicagomedicine.org)
Additionally, the outward side effects (weight gain and additional dark colored hair) were the result of excess hormones being produced by the tumor. (burzynskipatientgroup.org)
In most cases, these tumors make too much of certain hormones. (epnet.com)

Our team includes oncologists, pediatric surgeons, radiation oncologists, pathologists, interventional radiologists and psychosocial support staff with extensive experience with all tumor types. (cookchildrens.org)
The designation of a rare tumor is not uniform among pediatric and adult groups. (cancer.gov)
The Rare Tumors Program features treatment teams led by pediatric oncologists with special expertise in treating many rare forms of cancer. (childrenshospital.org)
Our pediatric oncologists may order a number of different tests to determine the type and location of the tumor. (childrenshospital.org)

Metastatic and recurrent adrenocortical cancer is not defined by its genomic landscape. (cdc.gov)

Expression profiles analysis identifies the values of carcinogenesis and the prognostic prediction of three genes in adrenocortical carcinoma. (cancerindex.org)

Carcinomas of pituitary gland, thyroid gland parathyroid gland and adrenal cortex (closed to accrual) 27. (sncrf.org)

The FNCLCC is based on tumor differentiation, tumor necrosis, and mitotic activity, while the NCI system bases the evaluation on histology, location, and tumor necrosis. (medscape.com)

[ 2 ] Tumors are further classified as benign, intermediate, or malignant, and intermediate tumors are designated as either locally aggressive or rarely metastasizing. (medscape.com)
Adrenocortical carcinoma is a rare, aggressive endocrine cancer with several unmet needs. (amend.org.uk)

Wilms tumor (nephroblastoma), an embryonal malignancy of the kidney, is the most common renal tumor of childhood [ Fernandez et al 2021 ]. (nih.gov)
Additional pathogenic variants transform nephrogenic rests into a Wilms tumor [ Fernandez et al 2021 ]. (nih.gov)

Most tumors that affect the adrenal cortex are adenomas. (medicalnewstoday.com)
The European Society of Endocrinology and the European Network for the Study of Adrenal Tumors has taken a simpler approach and recommend no further follow-up imaging for nodules less than 4 cm with a nonenhanced attenuation of less than 10 HU (ie, those that can be diagnosed as lipid-rich adenomas). (ctisus.com)

Review the mechanisms of predisposition to Wilms tumor. (nih.gov)
Provide an evaluation strategy to determine if a proband with Wilms tumor has a predisposition to Wilms tumor, identify the genetic or epigenetic mechanism for Wilms tumor, and determine risks for additional medical complications. (nih.gov)
Review management (e.g., tumor screening) recommendations for individuals with a genetic predisposition to Wilms tumor. (nih.gov)

In a large patient-population study in the United States, 3982 patients diagnosed with ACC were identified from the National Cancer Data Base (NCDB), and tumor, treatment, and hospital factors associated with survival after resection were examined. (medscape.com)
Radiation therapy is sometimes a treatment for tumors. (medlineplus.gov)
If the cyst or tumor is not painful and does not interfere with hearing, treatment is not necessary. (health32.com)
Treatment depends on the stage of the tumor. (epnet.com)
In most cases, this is the first treatment if the tumor is causing problems. (epnet.com)
Available at: https://www.cancer.gov/types/adrenocortical/patient/adrenocortical-treatment-pdq. (epnet.com)
These studies indicate the importance of the pyroptosis process in tumor development and treatment responses. (nature.com)

They are rare, benign tumors of epithelial origin and occur in less than 0.007-0.012% of the population. (medscape.com)
IntroductionParathyroid carcinoma (CaPa) is an extremely rare cause of primary hyperparathyroidism. (endocrine-abstracts.org)
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. (sncrf.org)

Anatomy5

Diseases24

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment10

Phenomena and Processes5

Disciplines and Occupations1

Health Care1

Melanoma5

Pheochromocytoma9

Neuroendocrine16

Prognosis10

Solid tumors5

Nasopharyngeal1

Adenoma5

Stromal tumors1

Metastatic adrenocortical carcinoma1

Depending on the type of tumor1

Type of tumor2

Germline5

Squamous Cell Carc3

Cancers2

Adrenal glands4

Suppressor3

Sarcoma1

Mutations3

Malignant bone tumors1

Cancerous6

Hyperplasia5

Diagnosis5

Types of adrenal2

Clinical10

Bilateral3

Patients with adrenocortical1

Pancreatic1

Known as adrenal1

Cushing1

20191

Surgical3

Testicular1

Larger tumors1

Size of the tumor1

Lesions2

Mitotane therapy1

Familial2

Metastases1

Urothelial Carcinoma1

Invasion of adjacent organs1

Molecular2

Germ1

Cystic1

Hormones4

Pediatric4

Recurrent1

Prognostic1

Parathyroid1

Histology1

Aggressive2

20212

Adenomas2

Predisposition3

Treatment7

Rare3