• Carcinomas of the eccrine sweat gland represent a rare group of tumors with potential for local destruction and metastasis. (medscape.com)
  • The specific classification of eccrine carcinomas is both complex and nebulous, mostly because of the paucity of reported cases but also because many of these tumors show little histologic resemblance to mature eccrine glands. (medscape.com)
  • [ 1 ] who divide these tumors into those that arise de novo in normal skin and those that originate within preexisting benign sweat gland tumors. (medscape.com)
  • [ 2 ] examining the incidence of cytogenetic abnormalities in malignant eccrine tumors showed low incidences of loss of heterozygosity (LOH) or TP53 alterations in a mixed group of these neoplasms, in contrast to the frequent and multiple genetic abnormalities seen in tumors arising from epidermal keratinocytes. (medscape.com)
  • Moreover, the antibody is particularly reactive in tumors of glandular origin (e.g. sweat glands). (histoprime.com)
  • Squamous cell carcinoma of varying degrees of differentiation is observed in 90% of patients with malignant tumors of the vulva. (med-blog.com)
  • The primary source of metastatic tumors is more oftentotal is squamous cell carcinoma of the cervix, then - cancer of the endometrium, bladder and urethra. (med-blog.com)
  • The etiological classification of squamous cell carcinoma of the vulva includes at least two groups: the smaller - basaloid and warty tumors induced by human papillomaviruses (HPV), and the larger - squamous cell carcinoma, the etiology of which is unknown. (med-blog.com)
  • Even though eccrine carcinomas would appear to be rare, when dealing with recurrent skin tumors or recurrent perianal fistulas, the possibility of eccrine carcinoma should be considered by consulting clinicians. (biomedcentral.com)
  • Thus, appropriate classification of such sweat glands, and associated tumors, enables us to devise a specific and appropriate sweat gland tumor therapeutical plan, and also an associated precise prognosis, i.e. apocrine carcinomas are able to metastasize to regional lymph nodes and do so frequently, whereas eccrine carcinomas are typically not able to metastasize [ 4 ]. (biomedcentral.com)
  • Retrospective evaluation of ceruminous gland tumors confined to the external ear canal of dogs and cats treated with biopsy and CO(2) laser ablation. (nih.gov)
  • In the 4th edition of WHO classification of tumors of female reproductive organs, primary villoglandular mucinous adenocarcinoma is defined as a primary invasive glandular epithelial tumor of intestinal type and the synonyms are cloacogenic carcinoma or cloacogenic adenocarcinoma [ 1 ]. (hindawi.com)
  • Tumors of the cutaneous adnexa arise from, or differentiate toward, structures in normal skin such as hair follicles, sweat ducts/glands, sebaceous glands, or a the disease and results in a specific diagnostic interpretation. (ejmjih.com)
  • This class of neoplasms includes benign tumors and highly aggressive carcinomas. (ejmjih.com)
  • 3 Histologically, the absence of keratinizing cysts and squamous differentiation (ie, islands with parakeratotic keratinization) distinguish SC from other sclerosing adnexal tumors such as microcystic adnexal carcinoma (MAC) and squamoid eccrine ductal carcinoma (SEDC), respectively. (appliedradiationoncology.com)
  • Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey. (nih.gov)
  • Malignant Sweat Gland Tumors. (nih.gov)
  • Multiple familial trichoepithelioma is a condition involving multiple skin tumors that develop from structures associated with the skin (skin appendages), such as hair follicles and sweat glands. (medlineplus.gov)
  • Affected individuals are also at increased risk of developing tumors in tissues other than skin appendages, particularly benign or malignant tumors of the salivary glands. (medlineplus.gov)
  • Intraepidermal Eccrine Adenocarcinomas (IEA) are rare malignant tumors derived from the eccrine sweat glands of the skin. (faoj.org)
  • were the first to describe tumors exhibiting features of the epidermal sweat duct. (faoj.org)
  • Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. (ijpmonline.org)
  • We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. (ijpmonline.org)
  • Objective: Laryngeal verrucous carcinoma (LVC) comprises 1% to 4% of all laryngeal tumors. (researchgate.net)
  • For many people with parotid gland tumors, surgery performed by a head and neck surgeon is the main treatment. (promisekit.org)
  • Oncocytic neoplasms are tumors composed of cells characterized by an aberrant amount of mitochondria that is responsible for their "swollen" (i.e. oncocytic) appearance [1]. (promisekit.org)
  • It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (lookformedical.com)
  • Tumors or cancer of the THYROID GLAND. (lookformedical.com)
  • Individuals in the United States can also be exposed to radioiodine, primarily 123I and 131I, as a result of clinical procedures in which radioiodine compounds are administered to detect abnormalities of the thyroid gland or to destroy the thyroid gland to treat thyrotoxicosis or thyroid gland tumors. (cdc.gov)
  • EPO-secreting tumors EPO-secreting tumors Polycythemia Vera , such as renal cell carcinoma Renal cell carcinoma Renal cell carcinoma (RCC) is a tumor that arises from the lining of the renal tubular system within the renal cortex. (lecturio.com)
  • Immunosuppression has been known to increase the risk of nonmelanoma skin cancers, particularly squamous cell carcinomas. (medscape.com)
  • Differential diagnosis initially included basosquamous carcinoma, acanthoytic squamous cell carcinoma, and adnexal tumor. (cdlib.org)
  • The antigen can also be detected in squamous cell carcinomas, even if the epithelium of origin (e.g. epidermis) itself is not reactive. (histoprime.com)
  • Common non melanoma skin cancers, such as basal and squamous cell carcinomas, show a UV-induced pathogenesis. (ejmjih.com)
  • In contrast to squamous cell carcinoma and basal cell carcinoma, molecular changes in adnexal neoplasia have been poorly characterized, and there are few published reviews on the current state of knowledge. (ejmjih.com)
  • Biopsy of the area confirmed squamous cell carcinoma (SCC), stage 1. (appliedradiationoncology.com)
  • 9 The documented link between previous radiation and developing MAC suggests that mutagenesis caused by radiation treatment for this patient's squamous cell carcinoma likely contributed to the development of syringomatous carcinoma. (appliedradiationoncology.com)
  • This report presents a unique case of likely radiation-induced syringomatous carcinoma in a patient previously treated with radiation for a left intranasal squamous cell carcinoma. (appliedradiationoncology.com)
  • On this review, all of us searched for to look into their term user profile in cervical squamous cell carcinoma (SCC) and also preneoplastic lesions on the skin to find out whether or not APR3 is actually involved in the malignant advancement of SCC. (pdesignaling.com)
  • In addition, a comparison with squamous cell carcinoma has not been reported previously. (dadospdf.com)
  • We found that the majority of microcystic adnexal carcinoma (92%) and desmoplastic trichoepithelioma (100%) cases expressed CK15 while the infiltrative basal cell carcinoma and squamous cell carcinoma cases were all negative. (dadospdf.com)
  • while only two microcystic adnexal carcinoma cases (15%) and one squamous cell carcinoma with ductal differentiation (12%) expressed CK7 in the remaining three tumor categories. (dadospdf.com)
  • While the neoplastic cells were negative, luminal staining of ductal structures was noted for CK7, CD15 and CEA in some of the microcystic adnexal carcinoma, desmoplastic trichoepithelioma and squamous cell carcinoma with ductal differentiation cases. (dadospdf.com)
  • Sixty percent of infiltrative basal cell carcinoma, 31% of microcystic adnexal carcinoma, and 25% of squamous cell carcinoma express CD10. (dadospdf.com)
  • BerEP4 expression was noted in 38% of microcystic adnexal carcinoma, 57% of desmoplastic trichoepithelioma, 100% of infiltrative basal cell carcinoma, and 38% of squamous cell carcinoma. (dadospdf.com)
  • In conclusion, we found CK15 to be a useful marker in distinguishing microcystic adnexal carcinoma from infiltrative basal cell carcinoma and squamous cell carcinoma with ductal differentiation. (dadospdf.com)
  • In addition, we noticed misdiagnosis of a few cases of microcystic adnexal carcinoma as squamous cell carcinoma at our institution-most likely a consequence of the biopsy technique (superficial shave). (dadospdf.com)
  • described a case of squamous cell carcinoma in situ occurring within a clear cell acanthoma. (statpearls.com)
  • Nasopharyngeal carcinomas (NPC) are non-keratinizing squamous cell carcinomas of the nasopharynx associated with Epstein-Barr virus (EBV). (researchgate.net)
  • Squamous cell carcinomas (SCCs) at high risk for local recurrence or metastasis are best treated with Mohs surgery. (medscape.com)
  • A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. (nih.gov)
  • On dermoscopy (Figure 2), the lesion appeared to be non-pigmented, cyst-like, and contained a network of fine serpiginous vessels, resembling micro-arborization typical of basal cell carcinoma (BCC). (cdlib.org)
  • After an incisional biopsy, her sample was firstly sent for anatomopathological study in a first pathology laboratory, chosen by the dermatologist, with the diagnostic hypothesis of basal cell carcinoma. (bvsalud.org)
  • As a dermatology resident in the early 1980s, the risk of developing a basal cell carcinoma (BCC) was considered considerable (I vaguely recall learning that it was in the 30% range). (aad.org)
  • Basal cell carcinomas are characterized by molecular alterations of the Hedgehog pathway, affecting patched and smoothened genes. (ejmjih.com)
  • Trichoepitheliomas are generally noncancerous (benign) but occasionally develop into a type of skin cancer called basal cell carcinoma . (medlineplus.gov)
  • Porocarcinoma (PC) and basal cell carcinoma (BCC) are distinct skin cancers. (e-acfs.org)
  • Basal cell carcinoma (BCC), which arises from the basal cells in the epidermis, is the most common form of skin cancer. (e-acfs.org)
  • Even though immunohistochemical comparisons of microcystic adnexal carcinoma vs infiltrative basal cell carcinoma and desmoplastic trichoepithelioma exist, they are mostly restricted to the use of a single stain. (dadospdf.com)
  • published online 7 December 2007 histopathologic perspective, the main differential diagnosis for microcystic adnexal carcinoma, a stratified, infiltrating neoplasm characterized by a superficial component of keratinous cysts and a deeper component of smaller nests and strands of cells embedded in a markedly hyalinized stroma, is sclerosing/infiltrative basal cell carcinoma and desmoplastic trichoepithelioma. (dadospdf.com)
  • The less common subtypes include eccrine mucinous carcinoma, malignant eccrine spiradenoma, malignant mixed tumor, malignant cylindroma, and papillary eccrine adenoma. (medscape.com)
  • We report an early case of primary cutaneous mucinous carcinoma in a male patient with chronic actinic damage. (cdlib.org)
  • A diagnosis of cutaneous mucinous carcinoma was made. (cdlib.org)
  • The final diagnosis was primary cutaneous mucinous carcinoma and definitive treatment was carried out via wide local excision. (cdlib.org)
  • Primary mucinous carcinoma (PMC) of the skin is a rare malignant neoplasm deriving from sweat glands [ 1 ]. (cdlib.org)
  • Fibroepitheliomatous Paget's phenomenon: fibroepithelioma-like changes associated with anogenital epidermotropic mucinous carcinoma. (markahurt.com)
  • An adenoma or carcinoma that arises from the ceruminous glands in the external auditory canal. (nih.gov)
  • The high proportion of mitotic cells and resemblance to well-differentiated adenocarcinoma of the large intestine suggested that this neoplasm was adenocarcinoma rather than adenoma. (hindawi.com)
  • sebaceous adenoma is a more benign [[neoplasm]] of the sebaceous glands. (wikidoc.org)
  • Carcinoma arising with a background of pleomorphic adenoma is well documented. (ijpmonline.org)
  • [ 4 ] suggest that genetics may play a role in the development of microcystic adnexal carcinoma (MAC). (medscape.com)
  • Rarely, other malignancies such as sebaceous carcinoma, microcystic adnexal carcinoma, and melanoma may complicate NS. (aad.org)
  • First reported in 1982 by Goldstein et al,1 microcystic adnexal carcinoma has been referred to by a variety of names-all of which allude to the clinical behavior and histopathologic features of this lesion. (dadospdf.com)
  • The differentiation of microcystic adnexal carcinoma from any of these other entities is not merely semantic but extremely relevant to clinical management. (dadospdf.com)
  • Microcystic adnexal carcinoma MP Hoang et al 179 believed to account for its high recurrence rate. (dadospdf.com)
  • While local recurrence is reported in 50% of cases of microcystic adnexal carcinoma with positive margins, 40-60% of patients experience one or more local recurrences anywhere from 6 months to 30 years after standard wide local excision.4,6,7,9-11 Thus, while the standard of care for microcystic adnexal carcinoma is wide local excision, no further management is mandated for a desmoplastic trichoepithelioma. (dadospdf.com)
  • Anatomopathological and immunohistochemical study revealed a preliminary diagnosis of breast carcinoma metastasis. (bvsalud.org)
  • New anatomopathological and immunohistochemical exams confirmed the diagnosis of breast carcinoma metastasis. (bvsalud.org)
  • This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
  • The anatomopathological report indicated breast carcinoma metastasis and the pathologist recommended a further immunohistochemical investigation to determine the neoplastic site of origin. (bvsalud.org)
  • Lymph node involvement is typically rare for eccrine carcinoma but distal metastasis is not uncommon [ 4 ]. (biomedcentral.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • The thyroid gland weighs, on average, 15 g, and is composed of two lateral lobes that extend to the sides of the larynx to very close to the midline of the thyroid cartilage, and that are joined by an isthmus that pass in front of the trachea. (teknon.es)
  • Multinodular goiter (MNG) is the most common disorder of the thyroid gland. (intechopen.com)
  • It starts as a diffuse enlargement of the thyroid gland and ends in a nodular enlarged thyroid. (intechopen.com)
  • Goiter is the enlargement of the thyroid gland which can be due to a variety of conditions. (intechopen.com)
  • Nodular goiter is one of the most common endocrine disorders affecting the thyroid gland. (intechopen.com)
  • Parotid gland oncocytoma is an uncommon, benign salivary neoplasm composed of mitochondria-rich epithelial cells called oncocytes. (promisekit.org)
  • Ameloblastoma is a benign epithelial odontogenic neoplasm which is common amongst the Yoruba ethinc group. (bvsalud.org)
  • Primary eccrine carcinomas are exceedingly rare, accounting for roughly 1 of 13,000 specimens submitted to a dermatopathology laboratory. (medscape.com)
  • Exceptions to this are the malignant chondroid syringoma and primary cutaneous adenoid cystic eccrine carcinoma, both of which occur more commonly in females than in males. (medscape.com)
  • The tumour-bearing tissue area and absolute carcinoma cell count per case were determined by image analysis and compared with a reference primary surgical specimen. (bvsalud.org)
  • Although the patient had no medical history of breast cancer, due to this result, she was referred to a mastologist, who investigated her breast nodules for the possible primary focus of the carcinoma. (bvsalud.org)
  • Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
  • The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)
  • Primary malignant neoplasms of the sweat glands are rare, constituting less than 1% of all primary malignant skin lesions 1 . (bvsalud.org)
  • Primary cutaneous cribriform apocrine carcinoma: Case report and literature review. (nih.gov)
  • Mister photo is the best photo paediatric primary immunodeficiency technique to gauge salivary sweat gland cancers. (hdac-inhibitors.com)
  • In some countries, maxillofacial surgeons are also involved in the primary treatment of neoplasm involving the salivary glands. (medscape.com)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • Renal cell carcinoma is responsible for 80%-85% of all primary renal neoplasms. (lecturio.com)
  • This is a unique case due to the low frequency 2 , the atypical clinical history, but mainly the difficult histopathological differential diagnosis and immunohistochemical evaluation among these neoplasms. (bvsalud.org)
  • Data on the Brazilian reality of anal sac carcinoma cases' diagnosis and treatment are also scarce. (pvb.com.br)
  • The purpose of this study was to retrospectively evaluate cases of canine anal sac carcinoma and assess the profile of involvement, tumor size, and lymphatic invasion at the time of diagnosis. (pvb.com.br)
  • Fourteen years after the diagnosis of syringomatous carcinoma, the patient presented for surgery to improve cosmesis and relieve breathing obstruction. (appliedradiationoncology.com)
  • It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease. (ijpmonline.org)
  • [ 1 ] This article reviews basic salivary anatomy and physiology, several important diseases affecting the glands, salivary constituents as measures of health, trends in diagnosis, and the management of xerostomia and drooling. (medscape.com)
  • A rare adnexal carcinoma that is histopathologically identical to homologous lesions in the salivary gland and breast. (nih.gov)
  • Many carcinomas are solid, while several cystic or mixed lesions are benign. (teknon.es)
  • the conspicuity of these lesions can be reduced due to a combination of the high density of the parotid gland and weak enhancement of the lesion. (promisekit.org)
  • Eccrine carcinoma is a quite rare malignant tumor that typically arises from a normal sweat gland and that features a rather high recurrence rate subsequent to simple excision. (biomedcentral.com)
  • Eccrine carcinoma is a rare, malignant sweat gland tumor, generally featuring a slow growth rate and a rather high local recurrence rate [ 2 ]. (biomedcentral.com)
  • For those that consider this entity to be a tumor, there is further disagreement whether this is a tumor of epidermal, pilar, or sweat gland origin. (statpearls.com)
  • Multiple pulmonary metastases from adenoid cystic carcinoma of ceruminous glands of external auditory canal. (nih.gov)
  • The purpose of this study was to investigate the correlation between cholesterol metabolic genes and the prognosis of clear cell renal cell carcinoma (ccRCC). (bvsalud.org)
  • En este estudio, examinamos si la intoxicación por TAA puede inducir la infiltración de leucocitos renales (medida como antígeno leucocitario común CD45) asociada con el aumento de las especies reactivas de oxígeno (ROS)/factor de necrosis tumoral-alfa (TNF-α), así como biomarcadores de daño renal con y sin tratamiento con metformina. (bvsalud.org)
  • Usando tinción histológica básica, métodos de inmunohistoquímica y análisis químico de la sangre, observamos una lesión profunda del tejido renal, como daño glomerular y tubular en el grupo experimental, que mejoraron sustancialmente con la metformina. (bvsalud.org)
  • La metformina también inhibió significativamente (p0,05) en la expresión renal de células de inmunotinción positivas para CD45. (bvsalud.org)
  • En conclusión, encontramos que el TAA induce la lesión renal en asociación con el aumento del eje ROS/TNF-α, independientemente de la infiltración de leucocitos, que está protegida por metformina. (bvsalud.org)
  • Additional benign neoplasms such as trichoepithelioma (8), tubular apocrine adenomas (9), sebaceomas (1), and others have been reported within NS. (aad.org)
  • An excision was performed and the histopathology revealed a carcinoma comprising strands, nests, and occasional glandular structures. (cdlib.org)
  • Apocrine skin carcinoma has characteristics similar to those of cutaneous breast carcinoma metastases when it presents a tubule-lobular, or cordonal differentiation. (bvsalud.org)
  • No specific data are available regarding United States versus international incidence of eccrine carcinoma. (medscape.com)
  • Sex incidence appears to be equal for eccrine carcinoma. (medscape.com)
  • In Russia, in the structure of the incidence of malignant neoplasms of the female genital organs, vulvar cancer is from 3 to 8% and takes fourth place. (med-blog.com)
  • The incidence of secondary neoplasms was statistically related to age and anatomic site (P (aad.org)
  • More generally, skin adnexal carcinomas have an incidence rate of 5.1 per 1 million person-years. (appliedradiationoncology.com)
  • The incidence of malignancy in MNG is 4-14%, and risk factors are family history of thyroid carcinoma, history of neck radiation, prior surgery, and presence of cervical lymphadenopathies. (intechopen.com)
  • High recurrence rates have been reported following conventional surgical excision of eccrine carcinomas. (medscape.com)
  • Eccrine carcinomas most commonly are diagnosed in patients in their sixth through eighth decades of life. (medscape.com)
  • A malignant acrospiroma is a sweat gland carcinoma of the hand, which may recur locally in 50% of patients after excision, with distant metastases occurring in 60% of patients. (wikipedia.org)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • Advanced photo tactics are reviewed, having a focus on diffusion-weighted and also dynamic compare image along with their chance to aid characterize gentle muscle growths Hydroxyurea molecular weight and help with unique cancer from civilized malignancies.Neoplasms from the salivary glands are seen as a Oral medicine their designated histologic variety definitely nonspecific imaging findings. (hdac-inhibitors.com)
  • The highest soft muscle resolution offered by magnet resonance photo is very useful in the monitoring associated with cancers with high propensities with regard to intraorbital, intracranial, as well as perineural condition propagate, which in turn normally include these because of the actual sinonasal tooth decay, nasopharynx, orbits, salivary glands, and also the pores and skin. (hdac-inhibitors.com)
  • Dentists are involved with aspects of salivary gland function in several ways, such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with salivary problems, in the treatment of caries and periodontal disease resulting from decreased salivary flow, and in controlling salivation during restorative procedures. (medscape.com)
  • Significant abnormality or disease of the salivary glands, such as that associated with Sjögren syndrome or neoplasm, necessitates additional evaluation by an otolaryngologist or an otolaryngologist/head and neck surgeon for comprehensive treatment of the gland pathology itself. (medscape.com)
  • Autonomic innervation of the salivary glands involves both parasympathetic and sympathetic input. (medscape.com)
  • Clinically, the most significant histological forms are malignant neoplasms developing from the integumentary squamous epithelium of the external genital organs. (med-blog.com)
  • Unfortunately, as far as we are aware, sweat gland carcinomas are often under diagnosed or misdiagnosed due to their clinical rarity [ 8 ]. (biomedcentral.com)
  • External auditory canal carcinoma: clinical characteristics and long-term treatment outcomes. (nih.gov)
  • Given its rather poor response to adjuvant therapy, wide excision of the lesion with tumor-free margins may offer a reasonable chance for long-term control of this neoplasm. (biomedcentral.com)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • It is unclear whether clear cell acanthoma represents a benign neoplasm or a reactive inflammatory dermatosis. (statpearls.com)
  • Treatment and survival outcomes of ceruminous carcinomas of the external auditory canal: a SEER database analysis and literature review. (nih.gov)
  • Ceruminous gland carcinomas: a clinicopathologic and immunophenotypic study of 17 cases. (nih.gov)
  • Ceruminous Neoplasms of the Ear. (nih.gov)
  • O objetivo do presente trabalho foi avaliar, de forma retrospectiva, os casos de carcinoma de saco anal canino, avaliando o perfil de acometimento, o tamanho tumoral e a invasão linfática no momento do diagnóstico. (pvb.com.br)
  • Such sweat glands are distributed over the entire body skin surface, with the greatest density being found on the palms of the hands and soles of the feet [ 1 ]. (biomedcentral.com)
  • To the best of our knowledge, this is the first systematic study describing the relationships between endoscopic tissue fragment number, actual infiltrated tumour area and carcinoma cell number. (bvsalud.org)