Hidradenomas are often sub-classified based on subtle histologic differences, for example: Eccrine acrospiroma Clear-cell hidradenoma or acrospiroma Nodular hidradenoma or acrospiroma Solid-cystic hidradenoma Discussion of sweat gland tumors can be difficult and confusing due to the complex classification and redundant terminology used to describe the same tumors. (wikipedia.org)
For example, acrospiroma and hidradenoma are synonymous, and sometimes the term acrospiroma is used to generally describe benign sweat gland tumors. (wikipedia.org)
There has also been a change in understanding about how tumors that were previously believed to strictly derive from specific sweat gland types may, in fact, derive from both eccrine or apocrine glands. (wikipedia.org)
Tumors of the cutaneous adnexa arise from, or differentiate toward, structures in normal skin such as hair follicles, sweat ducts/glands, sebaceous glands, or a the disease and results in a specific diagnostic interpretation. (ejmjih.com)
This class of neoplasms includes benign tumors and highly aggressive carcinomas. (ejmjih.com)
Adnexal tumors often present as solitary sporadic lesions, but can herald the presence of an inherited tumor syndrome such as Muir-Torre Syndrome, Cowden Syndrome, or CYLD Cutaneous Syndrome. (ejmjih.com)
Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey. (nih.gov)
Carcinomas of the eccrine sweat gland represent a rare group of tumors with potential for local destruction and metastasis. (medscape.com)
The specific classification of eccrine carcinomas is both complex and nebulous, mostly because of the paucity of reported cases but also because many of these tumors show little histologic resemblance to mature eccrine glands. (medscape.com)
[ 1 ] who divide these tumors into those that arise de novo in normal skin and those that originate within preexisting benign sweat gland tumors. (medscape.com)
[ 2 ] examining the incidence of cytogenetic abnormalities in malignant eccrine tumors showed low incidences of loss of heterozygosity (LOH) or TP53 alterations in a mixed group of these neoplasms, in contrast to the frequent and multiple genetic abnormalities seen in tumors arising from epidermal keratinocytes. (medscape.com)
Intraepidermal Eccrine Adenocarcinomas (IEA) are rare malignant tumors derived from the eccrine sweat glands of the skin. (faoj.org)
were the first to describe tumors exhibiting features of the epidermal sweat duct. (faoj.org)
Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. (ijpmonline.org)
We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. (ijpmonline.org)
CYLD cutaneous syndrome is a genetic condition characterized by the growth of multiple noncancerous (benign) skin tumors. (medlineplus.gov)
While the skin tumors associated with CYLD cutaneous syndrome are typically benign, occasionally they may become cancerous (malignant). (medlineplus.gov)
People with CYLD cutaneous syndrome typically begin developing tumors in late childhood or in their teens. (medlineplus.gov)
For reasons that are unclear, females with CYLD cutaneous syndrome tend to develop more tumors than males with this condition. (medlineplus.gov)
The tumors in CYLD cutaneous syndrome can be disfiguring and may contribute to depression or other psychological problems. (medlineplus.gov)
A heterogenous group of disorders characterized by the abnormal increase of MAST CELLS in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA). (sdsu.edu)
Carcinoma15
We report an early case of primary cutaneous mucinous carcinoma in a male patient with chronic actinic damage. (cdlib.org)
A diagnosis of cutaneous mucinous carcinoma was made. (cdlib.org)
The final diagnosis was primary cutaneous mucinous carcinoma and definitive treatment was carried out via wide local excision. (cdlib.org)
Primary mucinous carcinoma (PMC) of the skin is a rare malignant neoplasm deriving from sweat glands [ 1 ]. (cdlib.org)
Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)
Apocrine skin carcinoma has characteristics similar to those of cutaneous breast carcinoma metastases when it presents a tubule-lobular, or cordonal differentiation. (bvsalud.org)
A rare adnexal carcinoma that is histopathologically identical to homologous lesions in the salivary gland and breast. (nih.gov)
Secretory Carcinoma of the Eyelid Arising in an Adnexal Gland. (nih.gov)
Primary cutaneous cribriform apocrine carcinoma: Case report and literature review. (nih.gov)
Exceptions to this are the malignant chondroid syringoma and primary cutaneous adenoid cystic eccrine carcinoma, both of which occur more commonly in females than in males. (medscape.com)
Research gaps in the management and prevention of cutaneous squamous cell carcinoma in organ transplant recipients. (harvard.edu)
Hidradenoma1
Hidradenoma refers to a benign adnexal tumor of the apical sweat gland. (wikipedia.org)
Acrospiroma2
Acrospiroma is a cutaneous ailment that appears mainly in women and is a kind of benign adnexal neoplasm linked to poromo, a benign skin tumor. (wordinfo.info)
It's related to acrospiroma (also called poroma), a tumor of the distal part of the sweat gland. (facmedicine.com)
Approach to tumours1
Alsaad KO, Obaidat NA, Ghazarian D. Skin adnexal neoplasms--part 1: an approach to tumours of the pilosebaceous unit. (medscape.com)
CYLD Cutaneous Syndrome5
CYLD cutaneous syndrome includes the conditions previously called Brooke-Spiegler syndrome, multiple familial trichoepithelioma, and familial cylindromatosis. (medlineplus.gov)
The prevalence of CYLD cutaneous syndrome is unknown, but the condition is estimated to affect more than 1 in 100,000 individuals. (medlineplus.gov)
CYLD cutaneous syndrome is caused by mutations in the CYLD gene . (medlineplus.gov)
People with CYLD cutaneous syndrome are born with a mutation in one of the two copies of the CYLD gene in each cell. (medlineplus.gov)
In people with CYLD cutaneous syndrome, a second CYLD gene mutation typically occurs in multiple cells over an affected person's lifetime. (medlineplus.gov)
Tumours2
Paediatric cutaneous adnexal tumours: a study of 559 cases. (medscape.com)
Tumours of the brain arise from neoplasms in the meninges and intracranial tissues. (hafsaabbas.com)
Epithelial1
Ameloblastoma is a benign epithelial odontogenic neoplasm which is common amongst the Yoruba ethinc group. (bvsalud.org)
Malignancy2
They performed comparative studies of the cutaneous malignancy and breast nodules, especially with immunohistochemical examinations. (bvsalud.org)
Neutrophilic eccrine hidradenitis (NEH) is a neutrophilic dermatosis primarily affecting the eccrine glands and occurs most commonly in patients undergoing chemotherapy for a malignancy. (annals.edu.sg)
Mycosis Fungoides1
Mycosis Fungoides (MF) is a malignant neoplasm of T-lymphoytes, particularly of T-helper (Th) cells. (acadderm.com)
Adnexal tumor1
Folliculoma, also known as trichofolliculoma , is a type of benign cutaneous adnexal tumor. (medscape.com)
Skin12
The SCARB1-mediated cholesterol-dependent metabolism occurred both in ccRCC and skin cutaneous melanoma. (bvsalud.org)
With the emergence of many immunomarkers, immunohistochemistry has become a vital ancillary diagnostic tool in dermatopathology and an essential adjunct for the correct identification of skin neoplasms. (edu.au)
Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area. (bvsalud.org)
Cutaneous examination revealed multiple grouped monomorphic skin-colored papules present over both labia majora with a mild reduction in hair density over the affected area [Figure 1] a and [Figure 1] b. (ijstd.org)
Most swollen glands or lumps under the skin are not cause for concern. (healthlinkbc.ca)
Swollen glands and other lumps under the skin can be caused by many different things, including illness, infection, or another cause. (healthlinkbc.ca)
Cytoprotective Polyphenols Against Chronological Skin Aging and Cutaneous Photodamage. (harvard.edu)
HFSR due to TKIs usually manifests as a mild to moderate cutaneous reaction on the hands with a variant pattern, including a form in which bands of erythema alternate with normal skin. (oncologynurseadvisor.com)
Metastasis1
It is often misdiagnosed clinically since it has an uncharacteristic and variable presentation, and microscopically because it resembles a cutaneous metastasis from the more frequent mucinous adenocarcinomas of the colon, mammae, lungs and ovaries. (regionh.dk)
Spiroma List of cutaneous conditions List of cutaneous neoplasms associated with systemic syndromes Laws RA, English JC, Elston DM (November 1996). (wikipedia.org)
The patient remains well and free from any cutaneous or systemic symptoms 9 months after initial consultation. (cdlib.org)
Carcinomas1
However, research shows UVR is known to suppress sweating, which disrupts body thermoregulation, and a study analyzing TP53 mutations in 16 sweat gland carcinomas identified 3 G:C → A:T transitions at dipyrimidine sequences on the antisense strand. (medscape.com)
Nevus1
The authors concluded: "Our study confirms that most of the secondary neoplasms arising in association with nevus sebaceus are benign. (aad.org)
Lymphomas1
Cutaneous Lymphomas (CL) can be primary or secondary in origin. (acadderm.com)
Differential1
This is a unique case due to the low frequency 2 , the atypical clinical history, but mainly the difficult histopathological differential diagnosis and immunohistochemical evaluation among these neoplasms. (bvsalud.org)
Pathology2
Introduction to cutaneous pathology. (markahurt.com)
Dermatopathology is a joint subspecialty of dermatology and pathology or surgical pathology that focuses on the study of cutaneous diseases at a microscopic and molecular level. (ejmjih.com)
Commonly4
In addition, prognostic markers are evaluated and emphasis placed on the pitfalls commonly encountered when evaluating these neoplasms. (edu.au)
When two distinct neoplasms are located adjacent to the same cutaneous site, the phenomenon is commonly referred to as a collision tumor [ 1 , 2 ]. (e-acfs.org)
The glands ( lymph nodes ) on either side of the neck, under the jaw, or behind the ears commonly swell when you have a cold or sore throat. (healthlinkbc.ca)
Swollen glands commonly develop when the body fights infections from colds, insect bites, or small cuts. (healthlinkbc.ca)
Abnormalities2
Genetic mosaicism for somatic mutations of oncogenes is common in genodermatoses, which can be complicated with extra-cutaneous abnormalities. (nih.gov)
Additional benign neoplasms such as trichoepithelioma (8), tubular apocrine adenomas (9), sebaceomas (1), and others have been reported within NS. (aad.org)
Thyroid gland2
An enlarged thyroid gland ( goiter ) is in the neck just below the Adam's apple. (healthlinkbc.ca)
The thyroid gland produces the thyroid hormone which regulates the metabolism of the body. (skymd.com)
It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease. (ijpmonline.org)
Scalp1
Cylindromas were previously thought to derive from sweat glands, but they are now generally believed to begin in hair follicles and often appear on the scalp. (medlineplus.gov)
Syndromes1
3 Of the cutaneous toxicities experienced by patients, hand-foot syndromes (HFS)-also known as palmar-plantar erythrodysesthesia, palmar-plantar erythema, acral erythema, and Burgdorf's reaction -are becoming among the most common. (oncologynurseadvisor.com)
Vasculitis1
Cutaneous polyarteritis nodosa (CPN) is an uncommon form of vasculitis of the small-and medium-sized arteries in the reticular dermis and subcutaneous tissue. (annals.edu.sg)
Syndrome2
Various autoimmune diseases such as discoid lupus erythematosus, chronic cutaneous lupus erythematosus, Parry Romberg syndrome, and Graham-Little syndrome also lead to loss of hair. (skymd.com)
Hand-foot syndrome is a potentially dose-limiting cutaneous toxicity. (oncologynurseadvisor.com)