• Papillary eccrine adenoma is a cutaneous condition characterized by an uncommon benign sweat gland neoplasm that presents as a dermal nodule located primarily on the extremities of black patients. (wikipedia.org)
  • This may be because the cutaneous appendages are relatively protected from these mutagens by their deep dermal location. (logicalimages.com)
  • A rare benign cutaneous neoplasm containing keratinized epithelium and dermal derivatives, such as hair follicles, sweat and sebaceous glands, smooth muscle or fibroadipose tissue which usually manifests as a slow-growing, painless mass in the submandibular or sublingual space. (cdc.gov)
  • 15. Clear-cell dermal duct tumour: another distinctive, previously underrecognized cutaneous adnexal neoplasm. (nih.gov)
  • The origin of cutaneous tumors can be simplistically divided into three major categories: epidermal, dermal, and adnexal (see image below). (medscape.com)
  • Keratoacanthomas (KAs) are benign cutaneous neoplasms that occur in elderly patients who are frequently exposed to the sun. (medscape.com)
  • however, they can be seen with other sweat gland tumors such as cylindromas and trichoepitheliomas as part of Brooke-Spiegler syndrome, in which lesions may have combined features of cylindromas and spiradenomas. (medscape.com)
  • [ 5 ] However, CYLD mutations are not responsible for all sweat gland tumors, since a subset of patients with Brooke-Spiegler syndrome do not have a demonstrable germline CYLD mutation. (medscape.com)
  • One patient presented only with multiple cylindromas of the scalp but no other associated adnexal tumors of Brooke-Spiegler syndrome, while the second one developed multiple malignant tumors of skin and parotid glands. (cosmoderma.org)
  • Metastatic lesions represent up to 3% of malignant tumors of the thyroid gland. (bvsalud.org)
  • Eccrine spiradenoma, which was first described in detail by Kersting and Helwig in 1956, is an uncommon benign skin adnexal tumor originating from sweat glands [ 1 ]. (biomedcentral.com)
  • Acinic Cell Carcinoma A malignant glandular epithelial neoplasm consisting of secretory cells forming acinar patterns. (nih.gov)
  • Benign adnexal neoplasm whose glandular secretion includes the release of part of the secreting cell. (nih.gov)
  • In extramammary Paget disease , the atypical cells are thought to arise from intraepidermal sweat gland cells and demonstrate glandular features, including abundant basophilic cytoplasm, which can be highlighted by periodic acid-Schiff with diastase and mucin special stains. (medscape.com)
  • The name was coined by Billroth in 1859 for a salivary gland tumor with similar histopathology. (cosmoderma.org)
  • Adenoid cystic carcinoma (ACC) is commonly known as a malignant neoplasm of salivary glands in the head and neck region [ 1 ]. (hindawi.com)
  • have demonstrated that Merkel Cell polyomavirus (MCV or MCPyV) infects and proliferates within dermal fibroblasts under certain conditions 9 . (turkjpath.org)
  • It represents a benign dermal proliferation of fibroblasts and typically presents as a solitary, firm, often hyperpigmented nodule 0.3 to 1 cm in diameter ( picture 4A-B ). The pathogenesis, clinical presentation, diagnosis, and management of dermatofibroma are discussed in detail separately. (medilib.ir)
  • When inefficient duplication of telomeres occurs in dermal fibroblasts, senescence is the end result. (plasticsurgerykey.com)
  • It commonly arises in the head, neck, trunk and extremities as a dermal or subcutaneous nodule or papule and is sometimes accompanied with pain and tenderness [ 2 ]. (biomedcentral.com)
  • 19. Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma). (nih.gov)
  • Identification of epidermal Merkel cell carcinoma should prompt reexcision for evaluation of a possible dermal component. (medscape.com)
  • EBS is distinguished from other types of epidermolysis bullosa (EB) or non-EB skin fragility syndromes by the location of the blistering in relation to the dermal-epidermal junction. (beds.ac.uk)
  • Code Preferred Term Synonyms Definition Neoplastic Status C7419 Acanthoma A benign skin neoplasm composed of epithelial cells. (nih.gov)
  • Histology revealed a partially circumscribed nonencapsulated dermal proliferation of epithelial cells. (actasdermo.org)
  • A benign adnexal neoplasm derived from cells of the terminal duct of eccrine or apocrine SWEAT GLAND lineage. (nih.gov)
  • Representative examples include the acinar cell carcinoma of the pancreas and the acinar adenocarcinoma of the prostate gland. (nih.gov)
  • Eccrine gland carcinoma encompasses a rare group of sweat gland neoplasms that can be subdivided into many different types based on a wide histological spectrum. (logicalimages.com)
  • Eccrine gland carcinoma can arise de novo in a normal sweat gland structure, or it can represent a transformation of a pre-existing benign eccrine neoplasm. (logicalimages.com)
  • 8. Axillary apocrine carcinoma associated with apocrine adenoma and apocrine gland hyperplasia. (nih.gov)
  • The actual slides of the previous excision were not retrievable, while the pathology report did state that the lesion was "a basal cell carcinoma which in some areas presents gland-like formations, adenoid cystic characteristics and focal areas of keratinization, but it predominantly is an adenoid basal cell carcinoma. (hindawi.com)
  • Toker initially described it in 1972 when he reported five cases of trabecular carcinoma of the skin with a putative origin of eccrine sweat gland 4 . (turkjpath.org)
  • Sebaceous gland diseases are caused by lack of working in glands, excessive sebum production and inflammation. (esraazman.com)
  • COVID-19 has caused a delay in diagnosis of malignant neoplasms and consequently, this has resulted in poorer prognoses. (escholarship.org)
  • They must be differentiated from neurofibromas, which are usually larger and firmer than acrochordons ( picture 2 ), and from pedunculated dermal nevus ( picture 3 ). (medilib.ir)
  • It revealed an infiltrative dermal tumor composed of basaloid cells arranged in cords, nodules, and cribriform islands embedded in a fibrous stroma, with a lack of continuity with the surface epidermis. (hindawi.com)
  • Spiradenomas arise from the hair follicle bulge rather than the eccrine sweat gland, based on an immunohistochemical study of stem cell markers and with CD200. (medscape.com)
  • [ 1 ] Cylindromas are not restricted to skin but here we will focus on dermal cylindroma only. (cosmoderma.org)
  • Two to five million eccrine glands are distributed on almost the entire skin surface, with sparing of the lips, external auditory canal, glans penis, labia minora, and clitoris. (logicalimages.com)
  • Sweat Gland Awakening on Physical Training: A Skin Capacitance Mapping Observation. (uliege.be)
  • A non-metastasizing neoplasm that arises from the skin. (nih.gov)
  • These disorders range from potentially life-threatening skin cancers to annoying but harmless benign neoplasms such as seborrheic keratoses. (plasticsurgerykey.com)
  • Finally, OPCFRs act as endocrine disrupters, that affect many functions of the body such thyroid glands and reproductive functions, and may be involved in the development of diabetes and cancer. (ommegaonline.org)
  • Multiple KAs should raise suspicion of Muir-Torre syndrome, a genodermatosis with a defect in the MSH mismatch repair gene that is associated with sebaceous neoplasms and gastrointestinal cancers. (medscape.com)
  • Condition characterized by large, rapidly extending, erythematous, tender plaques on the upper body usually accompanied by fever and dermal infiltration of neutrophilic leukocytes. (lookformedical.com)
  • In current practice, they are considered to originate from the hair follicle bulge, rather than the sweat gland. (medscape.com)
  • Appropriate methodology does not exist to develop MRLs for dermal exposure. (cdc.gov)
  • However, current studies suggest four new candidates for the cellular basis: Epithelial progenitor cells, fibroblast and dermal stem cells, hair follicle stem cells, and pre/pro B cells 1 , 7 , 8 . (turkjpath.org)
  • Eccrine gland carcinomas can be locally invasive, but most pose a low risk for metastasis. (logicalimages.com)