• Examples of epithelial dysplasia include cervical intraepithelial neoplasia - a disorder commonly detected by an abnormal pap smear) consisting of an increased population of immature (basal-like) cells which are restricted to the mucosal surface, and have not invaded through the basement membrane to the deeper soft tissues. (wikipedia.org)
  • In this state, epithelial cells have lost their tissue identity and have reverted to a primitive cell form that grows rapidly and with abnormal regulation for the tissue type. (wikipedia.org)
  • The most widely used classification system is the World Health Organization (WHO) classification, based on the morphology of the epithelial cells and ratio of the lymphocytes to epithelial cells. (medscape.com)
  • One of the first lines of defense in the GI tract is the physical barrier provided by a single layer of intestinal epithelial cells. (sciencedaily.com)
  • However, in previous studies, NIAID scientists had observed that some Salmonella replicate rapidly in the cytosol -- the fluid portion -- of intestinal epithelial cells. (sciencedaily.com)
  • To address this question, the scientists genetically engineered Salmonella bacteria that self-destruct when exposed to the cytosol of epithelial cells but grow normally in other environments, including the lumen of the intestine. (sciencedaily.com)
  • Then they infected laboratory mice with the self-destructing Salmonella bacteria and found that replication in the cytosol of mouse intestinal epithelial cells is important for colonization of the GI tract and fuels fecal shedding. (sciencedaily.com)
  • The scientists hypothesize that, by hijacking the epithelial cell response, Salmonella amplify their ability to invade neighboring cells and seed the intestine for fecal shedding. (sciencedaily.com)
  • What is an Epithelial Cells in Urine Test? (medlineplus.gov)
  • Epithelial cells are a type of cell that covers the inside and outside of the surfaces of your body. (medlineplus.gov)
  • An epithelial cells in urine test looks at a sample of your urine (pee) under a microscope to count the number of epithelial cells in your urine. (medlineplus.gov)
  • It's normal to have a small number of certain types of epithelial cells in urine. (medlineplus.gov)
  • An epithelial cells in urine test is a part of a urinalysis , a test that measures different substances in your urine. (medlineplus.gov)
  • An epithelial cells in urine test is part of a microscopic exam of urine. (medlineplus.gov)
  • Why do I need an epithelial cells in urine test? (medlineplus.gov)
  • Your provider may have ordered an epithelial cells in urine test as part of your regular checkup or if the results of your visual or chemical urine tests weren't normal. (medlineplus.gov)
  • Is there anything else I need to know about an epithelial cells in urine test? (medlineplus.gov)
  • There are three types of epithelial cells that line the urinary tract. (medlineplus.gov)
  • If there are squamous epithelial cells in your urine, it may mean your sample was contaminated. (medlineplus.gov)
  • In response to damage, epithelial wounds repair by a series of events that integrate epithelial responses with those of resident and infiltrating immune cells including neutrophils and monocytes/macrophages. (jci.org)
  • Improved understanding of crosstalk between epithelial and immune cells during wound repair is necessary for development of better pro-resolving strategies to treat debilitating complications of disorders ranging from inflammatory bowel disease to diabetes. (jci.org)
  • The colonic epithelial turnover is driven by crypt-base stem cells that express the R-spondin receptor Lgr5. (nature.com)
  • Chemical injury induced by DSS leads to a loss of both Lgr5 + cells and Axin2 + cells and epithelial regeneration is driven by Axin2 − cells, including differentiated Krt20 + surface enterocytes. (nature.com)
  • We demonstrate that Rspo3 is essential for epithelial repair via induction of Wnt signaling in differentiated cells. (nature.com)
  • The majority of epithelial cells are therefore short-lived, in contrast to a limited number of long-lived stem cells in the base of the crypts. (nature.com)
  • While Lgr5 + cells are long-lived and act as stem cells during homeostatic conditions, experimental models have demonstrated that Lgr5 + stem cells per se are not essential for maintaining epithelial integrity 3 . (nature.com)
  • Thus, we find that endogenous Rspo3 signaling is a critical determinant of cellular fate within the crypt and stimulates rapid recruitment of differentiated cells for epithelial wound healing and crypt regeneration through induction of Wnt signaling. (nature.com)
  • Using RNA-Seq, we identified a total of 163 and 568 differentially expressed genes in primary normal human bronchial epithelial (NHBE) cells that were exposed to diacetyl and 2,3-pentanedione, respectively. (nature.com)
  • In this study, we utilized primary normal human bronchial epithelial (NHBE) cells that are cultured at an air-liquid interface (ALI) to mimic the in vivo airway characteristics 30 . (nature.com)
  • Extensive research on thymic epithelial cells (TEC) within the cortex and medulla has defined their essential roles during T-cell development. (frontiersin.org)
  • Significantly, there are additional non-epithelial stromal cells (NES) that exist alongside TEC within thymic microenvironments, including multiple subsets of mesenchymal and endothelial cells. (frontiersin.org)
  • Arguably, the most recognized and well-studied stromal populations in thymus biology are thymic epithelial cells (TEC) within the cortical and medullary areas, which are defined by their anatomical separation and function. (frontiersin.org)
  • Cortical epithelial cells (cTEC) support the earliest thymocyte progenitor populations, guiding them through the cortex, directing them to a T-cell lineage fate and ensuring their functional qualities as self-MHC restricted cells through the process of positive selection ( 2 ). (frontiersin.org)
  • Medullary epithelial cells (mTEC), in conjunction with dendritic cells, then take over control of developing thymocytes. (frontiersin.org)
  • Broadly separated into mesenchymal and endothelial cells, NES have been implicated in thymus organogenesis, thymocyte development, tolerance induction and development/maintenance of epithelial stroma. (frontiersin.org)
  • Our project goals are to define the factors involved in choroid plexus epithelial (CPe) cell development in mice, then apply this information to generate CPe cells from mouse and human embryonic stem cells (ESCs) for clinical applications. (ca.gov)
  • Unlike the invasive carcinomas, borderline ovarian tumors are characterized by cytoplasmic and nuclear atypia, (element of differential diagnosis with benign tumors), absence of stromal invasion, (element of differential diagnosis with malignant tumors), unusual degree of proliferation of the epithelial cells with cellular stratification including remarkable architectural atypia and the formation of papillary protuberances. (intechopen.com)
  • The primary barriers for invading respiratory pathogens are the airway epithelial cells of the respiratory tract and antimicrobial peptides produced by these cells. (cdc.gov)
  • Significant downregulation of β-defensin1 gene ( DEFB1 ) expression was observed when human bronchial epithelial cells (HBEpCs) were exposed to IAV. (cdc.gov)
  • Primary human bronchial epithelial cells HBEp cells. (cdc.gov)
  • Carbohydrate antigen 125 (CA-125) is a high molecular-weight glycoprotein expressed by epithelial ovarian tumors as well as on the surface of cells of mesothelial origin [ 10 ]. (hindawi.com)
  • Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts. (jci.org)
  • These studies demonstrate differential regulation of Na/H antiporter activity and mRNA abundance in renal epithelial cells and fibroblasts in response to an acidotic environment. (jci.org)
  • Upon division, the slow cycling limbal epithelial stem cells give rise to daughter cells known as transient amplifying (TA) cells. (molvis.org)
  • The EasySep™ Mouse Epithelial Cell Enrichment Kit II is designed to isolate epithelial cells from freshly dissociated mouse mammary tissues by immunomagnetic negative selection. (stemcell.com)
  • The EasySep™ procedure involves labeling unwanted non-epithelial cells with biotinylated antibodies and magnetic particles. (stemcell.com)
  • We determined the effect of vapour on oxidative stress-induced, PAFR-dependent pneumococcal adhesion to airway epithelial cells in vitro , and on pneumococcal colonisation in the mouse nasopharynx. (ersjournals.com)
  • Since invasive pneumococcal strains adhere to, and translocate across, respiratory tract epithelial cells, adhesion is a prerequisite for establishing pneumococcal disease [ 4 ]. (ersjournals.com)
  • Enteroids are three dimensional organoids derived from intestinal epithelial cells. (jove.com)
  • We introduce a class of Active Vertex Models (AVMs) for cell-resolution studies of the mechanics of confluent epithelial tissues consisting of tens of thousands of cells, with a level of detail inaccessible to similar methods. (cam.ac.uk)
  • By virtue of expressions of glial and neural surface markers and capability of neurotransmitter metabolism, amniotic epithelial cells are considered as candidate cell type for transplantation strategies to treat neurological disorders. (scielo.org.ar)
  • Previously, we have reported neurotrophism exhibited by human amniotic epithelial cells when transplanted after spinal cord injury in bonnet monkeys. (scielo.org.ar)
  • Amniotic epithelial cells were believed to secrete an 'Epidermal Growth Factor (EGF) - like' factor and exact identification was not made. (scielo.org.ar)
  • At this juncture, through the present study it was found that, chicken neural retinal cells when grown alone failed to survive and contrarily when either co-cultured with chicken amniotic epithelial cells / cultured in amniotic epithelial cell conditioned medium not only survived but also showed extensive differentiation. (scielo.org.ar)
  • It is interesting to note that while factor secreted by amniotic epithelial cells resembles EGF and/or FGF-2 in its biological action, known isoforms of them were not detected. (scielo.org.ar)
  • Considering the biological closeness between EGF and FGF-2, results indicate the possibility of a novel isoform of these growth factors secreted by amniotic epithelial cells. (scielo.org.ar)
  • Amniotic epithelial cells were known to express some of neuronal and glial cell markers (Sakuragawa et al. (scielo.org.ar)
  • Transplantation of amniotic epithelial cells in various regions of central nervous system such as caudate nucleus (Bankiewicz et al. (scielo.org.ar)
  • Amniotic epithelial cells transplantation in Parkinson model of rats was found to reverse the condition and prevent death in neurons (Kakishita et al. (scielo.org.ar)
  • 2001). In our previous report, we concluded the usefulness of amniotic epithelial cells transplantation in spinal cord injury repair research. (scielo.org.ar)
  • We had also outlined various biological and social advantages by which, amniotic epithelial cells transplantation excels its precedent viz. (scielo.org.ar)
  • Recently, our conclusion of usefulness of amniotic epithelial cells transplantation to treat spinal cord injuries has been confirmed in rodent models of spinal cord injury (Zhi-yuan et al. (scielo.org.ar)
  • Based on the neurotropism exerted by amniotic epithelial cells conditioned medium, a diffusible neurotrophic factor produced by them had been suggested as a possible cause apart from direct cell-to-cell effects (Uchida et al. (scielo.org.ar)
  • 2001) had found amniotic epithelial cells conditioned medium showed neurotrophic effect on rat embryonic day 18 (E18) cortical neurons. (scielo.org.ar)
  • However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. (lu.se)
  • NRG1α was detected in serous cells within normal submucosal glands and in epithelial cells lining honeycombing areas in IPF, and was not detected in other patients. (bmj.com)
  • Conclusion Expression of SOX2 and MUC5B and lack of SPDEF in atypically differentiated cells of bronchiolised distal airspaces are consistent with abnormal programming of airway epithelial cells in IPF. (bmj.com)
  • These fluorescently tagged nanoparticles were both filtered and internalized by renal tubular epithelial cells in a dose- and time-dependent fashion. (harvard.edu)
  • Because the lens is constantly exposed to UV irradiation, we studied its effects on ferritin synthesis and Fe metabolism in cultured lens epithelial cells with and without ascorbic acid (Asc). (bioone.org)
  • J. Harned , A. M. Grimes , and M. C. McGahan "The Effect of UVB Irradiation on Ferritin Subunit Synthesis, Ferritin Assembly and Fe Metabolism in Cultured Canine Lens Epithelial Cells," Photochemistry and Photobiology 77(4), 440-445, (1 April 2003). (bioone.org)
  • Here, we use primary nasal epithelial cells (NECs) from children and adults, differentiated at an air-liquid interface to show that the ancestral SARS-CoV-2 replicates to significantly lower titers in the NECs of children compared to those of adults. (plos.org)
  • As malignant cells have a tendency to round up in body fluids these non-epithelial neoplasms can therefore mimic reactive mesothelial cells and metastatic adenocarcinoma. (cytojournal.com)
  • Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells. (uni-muenchen.de)
  • In this study, we analysed the intracellular carbon metabolism of enteroinvasive Escherichia coli (EIEC HN280 and EIEC 4608-58) and Salmonella enterica Serovar Typhimurium (Stm 14028) replicating in epithelial colorectal adenocarcinoma cells (Caco-2). (uni-muenchen.de)
  • Enhanced mucosal CK2 protein expression and activity were observed in animal models of chronic colitis, particularly within intestinal epithelial cells (IECs). (diva-portal.org)
  • A number of COX inhibitors in cultured human airway cells were compared which exclusively express either COX 1 (primary degree cultured human airway smooth muscle (HASM) cells) or COX 2 (A549 pulmonary epithelial cell-line) as measured by Western blotting. (ersjournals.com)
  • Using real-time, quantitative PCR, laser capture microdissection, and immunohistochemistry, distinctive patterns of expression of the hedgehog pathway members patched 1 (PTCH1), smoothened, GLI1, GLI2 and the 3 hedgehog ligands were identified for epithelial cells and stromal fibroblasts in benign breast and breast cancer. (rti.org)
  • Hedgehog ligands were expressed at higher levels in some cancer epithelial cell lines compared to noncancerous epithelial cells. (rti.org)
  • Hedgehog-mediated transcription, as indicated by a reporter of GLI-dependent promoter activity and by expression of GLI1 transcripts, was reduced by the hedgehog pathway inhibitor cyclopamine in both MDA-MB-435 cancer epithelial cells and MCF10AT epithelial cells, a cell line derived from benign breast. (rti.org)
  • However, cyclopamine reduced viability of cancer epithelial cell lines, including MDA-MB-435, but did not specifically affect fibroblasts or epithelial cells from benign breast, including MCF10AT. (rti.org)
  • These results demonstrate modulation of GLI-mediated transcription in both cancer and benign-derived epithelial cells by cyclopamine and sonic hedgehog, and further suggest that hedgehog signaling contributes to the survival of only the cancer epithelial cells. (rti.org)
  • In the current study, we collected high-throughput gene expression data related to human lung epithelial cells infected with SARS-CoV-2 or other respiratory viruses (SARS, H1N1, rhinovirus, avian influenza, and Dhori) and compared the effect of these viruses on the human transcriptome. (biorxiv.org)
  • Title : Tissue cultures of KB epithelial cells for poliomyelitis virus tests Personal Author(s) : Luoto, Lauri;Pickens, Edgar G. (cdc.gov)
  • Interestingly, a subpopulation of cells overexpressing SIRT7 exhibited an intermediate stage between mesenchymal and epithelial characters . (bvsalud.org)
  • Transformed epithelial cells showed a loss of heterochromatisation as evidenced by a loss of HP1α and H3K9 dimethylation staining . (bvsalud.org)
  • Alveolar epithelial cells (AEC) have been implicated in pathological remodelling. (lu.se)
  • Finally, ODE-induced Muc5ac levels were enhanced in MyD88-deficient airway epithelial cells in vitro. (cdc.gov)
  • A graphical representation of variants found in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stock P1 and P2, as well as the apical washes from SARS-CoV-2-infected monkey and cat airway epithelial cell cultures with either P1 or P2 stock 96 hpi at 33°C or 37°C. SARS-CoV-2/Wuhan-Hu-1 (GenBank accession no. (cdc.gov)
  • Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. (lu.se)
  • Results In IPF, the bronchiolised and enlarged distal airspaces stained for SOX2 are consistent with epithelial differentiation characteristic of conducting airway epithelium. (bmj.com)
  • MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultur al organic dust exposure. (cdc.gov)
  • Thymic epithelial neoplasms or tumors, also known as thymoma and thymic carcinoma, are the most common primary neoplasms of the anterior mediastinum. (medscape.com)
  • The eighth edition of the TNM classification of malignant tumors includes an official staging system for thymic epithelial tumors recognized by the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC). (medscape.com)
  • Thymic epithelial tumors with clearly invasive or metastatic features seen on CT are associated with having higher AJCC/UICC pathologic TNM stage. (medscape.com)
  • Borderline epithelial tumors are also known as atypical proliferating tumors and used to be called low malignant potential tumors . (cancer.org)
  • These tumors look the same as invasive epithelial ovarian cancers when seen on an ultrasound or CT scan. (cancer.org)
  • Borderline ovarian tumors represent 10-20% of epithelial ovarian neoplasm's [ 5 ] with an incidence of 1.8-4.8 out of 100.000 women per year [ 6 ] and typically have an excellent prognosis. (intechopen.com)
  • Ovary surface epithelial tumor tissue array (1.5mm), 48 cases of benign and malignant tumors. (delos.info)
  • Designed for IHC or ISH based protein or RNA tissue profiling in benign and malignant ovary surface epithelial tumors. (delos.info)
  • Epithelial cystic tumors account for about 60% of all true ovarian neoplasms. (medscape.com)
  • Mucinous epithelial tumors account for approximately 10-15% of all epithelial ovarian neoplasms. (medscape.com)
  • While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
  • Most tumors metastatic to the serous membranes are of epithelial origin. (cytojournal.com)
  • Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
  • Other rare non-epithelial malignancies that may be encountered in effusion cytology include neuroblastoma, Wilms tumor, and metastatic brain tumors. (cytojournal.com)
  • Solid epithelial ovarian tumors are almost invariably malignant. (medscape.com)
  • Skin and intestinal epithelial barriers play a pivotal role in protecting underlying tissues from harsh external environments. (jci.org)
  • The molecular mechanisms that restore intestinal epithelial homeostasis during colitis are incompletely understood. (diva-portal.org)
  • The in vitro treatment of intestinal epithelial cell lines with cytokines resulted in increased CK2 expression and nuclear translocation of its catalytic alpha subunit. (diva-portal.org)
  • Epithelial dysplasia, a term becoming increasingly referred to as intraepithelial neoplasia, is the sum of various disturbances of epithelial proliferation and differentiation as seen microscopically. (wikipedia.org)
  • The inverse correlation between Notch signaling and the proliferative status of the corneal epithelium is consistent with the idea that Notch plays a role in corneal epithelial differentiation. (molvis.org)
  • Activation of abnormal respiratory epithelial differentiation programs may contribute to the expression of MUC5B and bronchiolisation of the distal lung, a salient feature of IPF. (bmj.com)
  • The hedgehog pathway regulates epithelial-mesenchymal interactions, differentiation, proliferation and survival during development. (rti.org)
  • Cytokines, growth factors, Wnt ligands, SPMs, and MMPs released in the wound microenvironment in response to injury support epithelial cell proliferation as well as migration. (jci.org)
  • Focal Epithelial Hyperplasia (FEH) or Heck's disease is a rare and benign condition characterized by cell proliferation in the squamous epithelium, which is manifested clinically as verrucous projections. (bvsalud.org)
  • Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
  • 4 Malignant effusions caused by non-epithelial neoplasms are more frequently encountered in children than in adults. (cytojournal.com)
  • Other changes that occur in epithelial dysplasia include: Drop-shaped rete processes Basal cell hyperplasia Irregular epithelial stratification Increased nuclear-cytoplasmic ratio Increased normal and abnormal mitosis Enlarged nucleoli Individual cell keratinization Loss or reduction of cellular cohesion Cellular pleomorphism Loss of basal cell polarity Koilocytosis Epithelial cell dysplasia is divided into three categories of severity: mild, moderate, and severe. (wikipedia.org)
  • Focal epithelial hyperplasia (FEH) or Heck's disease is a rare, benign, oral condition that is associated with infection by human papillomavirus type 13, 32 or both. (nih.gov)
  • multifocal epithelial hyperplasia. (nih.gov)
  • Lesions underwent incisional biopsy, and the microscopic analysis revealed epithelial changes such as epithelium hyperplasia and prominent acanthosis. (bvsalud.org)
  • The focal epithelial hyperplasia (FEH) or Heck's disease is a benign and relatively rare condition associated with human papillomavirus (HPV) subtype 13 or 32 1-7 . (bvsalud.org)
  • Nasal epithelial PAFR was assessed in non-vaping controls, and in adults before and after 5 min of vaping. (ersjournals.com)
  • There was no difference in baseline nasal epithelial PAFR expression between vapers (n=11) and controls (n=6). (ersjournals.com)
  • The Masaoka-Koga classification describes the extent and spread of thymic epithelial malignancies. (medscape.com)
  • Corneal epithelial-stromal and stromal dystrophies are a group of inherited disorders of the cornea that are caused by progressive accumulation of deposits within the layers of the cornea. (uiowa.edu)
  • Lattice corneal dystrophy (LCD) is the most common of the corneal epithelial-stromal dystrophies. (uiowa.edu)
  • In early experiments, physical separation of mesenchymal and epithelial stroma from embryonic murine thymus resulted in defective thymus development when epithelium was cultured in vitro in the absence of mesenchyme ( 7 ). (frontiersin.org)
  • Epithelial dysplasia becomes microinvasive squamous cell carcinoma once the tumor begins to invade nearby tissue. (wikipedia.org)
  • The micro changes will gradually be seen in oesophagus lining, as the smooth surface of the squamous epithelial layer begins to form a fingerlike cellular pattern, also known as villiform. (techscience.com)
  • SIRT7 overexpression in immortalized mouse fibroblasts (NIH3T3) induced epithelial transition. (bvsalud.org)
  • Sirtuin 7 Promotes Mesenchymal to Epithelial Transition by ß-Catenin Redistribution and Stabilization. (bvsalud.org)
  • The aim of this study was to evaluate the efficacy and safety of GTS compared to hook knife plus coagrasper (HKC) for ESD of gastric epithelial neoplasia. (wjgnet.com)
  • GTS is a safe and effective device for ESD of gastric epithelial neoplasia compared with HKC. (wjgnet.com)
  • BACKGROUND Use of the conventional Western and Japanese classification systems of gastrointestinal epithelial neoplasia results in large differences among pathologists in the diagnosis of oesophageal, gastric, and colorectal neoplastic lesions. (bmj.com)
  • AIM To develop common worldwide terminology for gastrointestinal epithelial neoplasia. (bmj.com)
  • Can CA-125 Predict Lymph Node Metastasis in Epithelial Ovarian Cancers in Turkish Population? (hindawi.com)
  • Although CA-125 in epithelial ovarian cancers, which varies extensively depending on racial and genetic differences, has been studied extensively, the effect of preoperative CA-125 levels in predicting lymph node metastases is controversial. (hindawi.com)
  • Background: The neural transcription factor SOX11 has been described as a prognostic marker in epithelial ovarian cancers (EOC), however its role in individual histological subtypes and tumour grade requires further clarification. (lu.se)
  • CIL:24526, Rattus norvegicus, epithelial cell. (ucsd.edu)
  • CONCLUSION The differences between Western and Japanese pathologists in the diagnostic classification of gastrointestinal epithelial neoplastic lesions can be resolved largely by adopting the proposed terminology, which is based on cytological and architectural severity and invasion status. (bmj.com)
  • 1 , 3 These discrepancies therefore called for a united effort to reach a consensus on the nomenclature of gastrointestinal epithelial neoplastic lesions. (bmj.com)
  • Different pathologists have their own interpretations and opinions of the histopathological definitions of dysplastic epithelial lesions. (techscience.com)
  • Epithelial ovarian cancer (EOC) is the sixth most frequent cause of cancer death in women and is the leading cause of mortality resulting from overall gynecologic malignancies in the United States and Europe [ 1 ]. (hindawi.com)
  • In this Review we focus on epithelial and innate immune cell interactions that mediate wound healing and restoration of tissue homeostasis in the skin and intestine. (jci.org)
  • The epithelial layer's depth is estimated from the tissue edges and the connected nucleolus only. (techscience.com)
  • The improved results demonstrate that curvatures have been effective in reducing the boundary effects on the epithelial layer of tissue. (techscience.com)
  • The textural and spatial features on the detected epithelial layer can capture the changes in tissue. (techscience.com)
  • Individual cellular features of dysplasia are called epithelial atypia. (wikipedia.org)
  • Although the conclusions mentioned above were reached 16 and 12 years back respectively, the recent research on dysplasia grading agreements in 2014 and 2016 show that the findings are still valid as the agreement on colon and oral epithelial indefinite dysplasia score less than 0.3 kappa (fair agreement) [ 9 , 10 ]. (techscience.com)
  • The 2015 International Committee for Classification of Corneal Dystrophies (IC3D) classification system has divided corneal dystrophies into 4 categories: epithelial and subepithelial dystrophies, epithelial-stromal dystrophies, stromal dystrophies, and endothelial dystrophies. (uiowa.edu)
  • According to GlobalData, Phase I drugs for Epithelial Ovarian Cancer have an 85% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. (pharmaceutical-technology.com)
  • This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. (lu.se)
  • Further in vitro studies revealed that CK2 activity promotes epithelial restitution, and protects normal IECs from cytokine-induced apoptosis. (diva-portal.org)
  • What cellular mechanisms govern early morphogenesis of epithelial appendages? (helsinki.fi)
  • We strive to understand the molecular and cellular regulation of epithelial appendage (hair, mammary gland, tooth) development and how they are perturbed in diseases such as congenital disorders or tumorigenesis. (helsinki.fi)
  • What cellular mechanisms drive mammary epithelial invasion and branching? (helsinki.fi)
  • The AVMs combine the Vertex Model for confluent epithelial tissues with active matter dynamics. (cam.ac.uk)
  • While many studies have demonstrated the importance of cTEC and mTEC during T-cell development, thymic stromal microenvironments also contain heterogenous non-epithelial stromal (NES) populations in a similar manner to that seen in peripheral lymphoid tissues. (frontiersin.org)
  • Dynamic remodeling of focal adhesion complexes and actin promotes interactions with the ECM that facilitate the epithelial sheet's migration. (jci.org)
  • Following initial epithelial cell migration, keratinocytes peripheral to the leading edge proliferate and mature to restore epithelial barrier homeostasis and function. (jci.org)
  • In this review, we cover how the non-epithelial compartment of thymic stroma represent essential cell populations in regulating thymus function. (frontiersin.org)
  • Micrograph is of a thin section cut from an epithelial cell in the developing thymus of a newborn rat. (cellimagelibrary.org)
  • The role of single preoperative serum CA-125 levels in predicting pelvic or paraaortic lymph node metastasis in patients operated for epithelial ovarian cancer has been investigated. (hindawi.com)
  • We also include cell alignment, cell-specific mechanical properties, cell growth, division and apoptosis as well as a flexible, dynamically changing boundary of the epithelial sheet. (cam.ac.uk)
  • Therefore, this work proposed a curvature detection to reduce the boundary effects and estimates the epithelial layer. (techscience.com)