AnatomyDiseasesChemicals and DrugsPhenomena and ProcessesInformation Science
Adenoma, Sweat GlandSweat Gland NeoplasmsSweat GlandsSweatSalivary Gland NeoplasmsSebaceous Gland NeoplasmsAnal Gland NeoplasmsEccrine GlandsPerianal GlandsSublingual Gland NeoplasmsAdenoma, PleomorphicParotid NeoplasmsCarcinoma, MucoepidermoidSweatingPalatal NeoplasmsChloropreneCarcinoma, Adenoid CysticMyoepitheliomaAdenolymphomaSweat Gland DiseasesApocrine GlandsSubmandibular Gland NeoplasmsSalivary Glands, MinorEctodysplasinsSalivary GlandsEndocrine Gland NeoplasmsExocrine GlandsAcrospiromaEncyclopedias as TopicPoroma
Nodular hidradenomaAdnexal neoplasmsTumorsTumorCutaneousBenign sweat glandDuctHidradenocarcinomaCarcinomasAcanthomaPoromasSkinFactRoleClear Cell HidradenomaAdenomaNodularPapilliferumSebaceousCarcinomaMalignant eccrineEpithelialEccrine glandsEyelidPapillary structuresSecretoryCarcinomasDermisOccurPituitaryConditionsBreast
Nodular hidradenoma3
  • Hidradenomas are often sub-classified based on subtle histologic differences, for example: Eccrine acrospiroma Clear-cell hidradenoma or acrospiroma Nodular hidradenoma or acrospiroma Solid-cystic hidradenoma Discussion of sweat gland tumors can be difficult and confusing due to the complex classification and redundant terminology used to describe the same tumors. (wikipedia.org)
  • Gross pathology of a cystic nodular hidradenoma Dermal duct tumor Acrospiroma, solid type Acrospiroma, clear cell type Wikimedia Commons has media related to Hidradenoma. (wikipedia.org)
  • Nodular hidradenoma and hidradenocarcinoma. (wikipedia.org)
Adnexal neoplasms1
  • We aimed to review the clinical, morphological and molecular features of this category of adnexal neoplasms with a special focus upon emerging differential diagnoses, and discuss how their systematic molecular characterisation may contribute to a standardisation of diagnosis, more accurate classification and, ultimately, refinement of their prognosis and therapeutic modalities. (bvsalud.org)
Tumors9
  • For example, acrospiroma and hidradenoma are synonymous, and sometimes the term acrospiroma is used to generally describe benign sweat gland tumors. (wikipedia.org)
  • There has also been a change in understanding about how tumors that were previously believed to strictly derive from specific sweat gland types may, in fact, derive from both eccrine or apocrine glands. (wikipedia.org)
  • Carcinomas of the eccrine sweat gland represent a rare group of tumors with potential for local destruction and metastasis. (medscape.com)
  • The specific classification of eccrine carcinomas is both complex and nebulous, mostly because of the paucity of reported cases but also because many of these tumors show little histologic resemblance to mature eccrine glands. (medscape.com)
  • [ 1 ] who divide these tumors into those that arise de novo in normal skin and those that originate within preexisting benign sweat gland tumors. (medscape.com)
  • [ 2 ] examining the incidence of cytogenetic abnormalities in malignant eccrine tumors showed low incidences of loss of heterozygosity (LOH) or TP53 alterations in a mixed group of these neoplasms, in contrast to the frequent and multiple genetic abnormalities seen in tumors arising from epidermal keratinocytes. (medscape.com)
  • Recurrent oncogenic drivers have been identified in a variety of sweat gland tumors. (bvsalud.org)
  • The main objectives of the present study were (i) to provide an overview of the prevalence of previously identified oncogenic drivers in acral sweat gland tumors and (ii) to genetically characterize tumors in which no recurrent genetic alteration has been identified yet. (bvsalud.org)
  • Cases of acral sweat gland tumors were identified from the database of the French network CARADERM. (bvsalud.org)
Tumor3
Cutaneous3
  • Spiroma List of cutaneous conditions List of cutaneous neoplasms associated with systemic syndromes Laws RA, English JC, Elston DM (November 1996). (wikipedia.org)
  • The fusion genes frequently involve MAML2 and NUTM1, which are also rearranged in other cutaneous and extracutaneous neoplasms. (bvsalud.org)
  • We report the clinical and histologic presentation of 51 cutaneous melanocytic neoplasms with a PKC fusion gene (involving PRKCA in 35 cases, PRKCB in 15 cases, and PRKCG in a single case). (bvsalud.org)
Benign sweat gland1
  • Poroma is a benign sweat gland tumour showing morphological features recapitulating the superficial portion of the eccrine sweat coil. (bvsalud.org)
Duct1
  • Poroma is a benign adnexal neoplasm of the intraepidermal portion of the sweat gland duct, called the acrosyringium . (clinicaladvisor.com)
Hidradenocarcinoma1
  • MAML2 fusion was identified in cases of hidradenoma and hidradenocarcinoma (n=9/12 and n=9/12). (bvsalud.org)
Carcinomas1
  • However, research shows UVR is known to suppress sweating, which disrupts body thermoregulation, and a study analyzing TP53 mutations in 16 sweat gland carcinomas identified 3 G:C → A:T transitions at dipyrimidine sequences on the antisense strand. (medscape.com)
Acanthoma1
  • In fact, clear cell acanthoma possesses a similar staining pattern to inflammatory dermatoses such as psoriasis vulgaris, lichen planus, and discoid lupus erythematosus and might be a localized form of inflammatory eruption rather than a neoplasm. (medscape.com)
Poromas1
  • 2 With time, it became evident that poromas of an eccrine lineage also exist, but the historic view of poromas as neoplasms of eccrine lineage has persisted such that many poromas are assumed to be eccrine poromas. (clinicaladvisor.com)
Skin2
  • With the emergence of many immunomarkers, immunohistochemistry has become a vital ancillary diagnostic tool in dermatopathology and an essential adjunct for the correct identification of skin neoplasms. (edu.au)
  • The complexity of some skin neoplasms makes it imperative that the role of immunohistochemistry in subtyping these conditions is clearly understood. (edu.au)
Fact1
  • The authors hypothesize that this difference may be partly explained by the fact that the bulk of eccrine sweat glands lie deep in the dermis, an environment relatively protected from the sun and environmental mutagens. (medscape.com)
Role1
Clear Cell Hidradenoma4
  • Hidradenomas are often sub-classified based on subtle histologic differences, for example: Eccrine acrospiroma Clear-cell hidradenoma or acrospiroma Nodular hidradenoma or acrospiroma Solid-cystic hidradenoma Discussion of sweat gland tumors can be difficult and confusing due to the complex classification and redundant terminology used to describe the same tumors. (wikipedia.org)
  • 14. Giant clear cell hidradenoma of the knee. (nih.gov)
  • 19. Perineal Clear Cell Hidradenoma: A GATA3-positive Neoplasm With Potential for Misdiagnosis. (nih.gov)
  • 20. MRI of clear cell hidradenoma. (nih.gov)
Adenoma2
  • WHO, 2001) Malignant C45929 Acidophil Stem Cell Pituitary Gland Adenoma Acidophil Stem Cell Adenoma An infrequent pituitary gland adenoma composed of cells showing immunoreactivity for prolactin and less often growth hormone. (nih.gov)
  • A cystic form of sweat gland adenoma (ADENOMA, SWEAT GLAND). (bvsalud.org)
Nodular3
  • Gross pathology of a cystic nodular hidradenoma Dermal duct tumor Acrospiroma, solid type Acrospiroma, clear cell type Wikimedia Commons has media related to Hidradenoma. (wikipedia.org)
  • Nodular hidradenoma and hidradenocarcinoma. (wikipedia.org)
  • 8. Nodular hidradenoma in a 19-year-old woman. (nih.gov)
Papilliferum5
  • Hidradenoma papilliferum (HP) is a benign epithelial tumor most commonly seen in the vulva. (nih.gov)
  • Hidradenoma papilliferum is a sweat gland neoplasm that presents almost exclusively in the vulva or perianal area of women. (surgpath4u.com)
  • This is in contrast to syringocystadenoma papilliferum, another sweat gland neoplasm with similar histology, but which does connect to the epidermis, is usually located in the head or neck and has prominent plasma cells. (surgpath4u.com)
  • 7. Hidradenoma papilliferum of nasal skin. (nih.gov)
  • 11. Hidradenoma papilliferum of the vulva: case report and review of literature. (nih.gov)
Sebaceous3
  • Hidradenoma is a relatively rare benign tumor of sweat gland origin that can rarely arise within a nevus sebaceous. (cdlib.org)
  • We present an interesting case of a hidradenoma and sebaceoma arising within a nevus sebaceous and present a literature review of the 2 conditions. (cdlib.org)
  • Multiple KAs should raise suspicion of Muir-Torre syndrome, a genodermatosis with a defect in the MSH mismatch repair gene that is associated with sebaceous neoplasms and gastrointestinal cancers. (medscape.com)
Carcinoma4
  • Acinic Cell Carcinoma A malignant glandular epithelial neoplasm consisting of secretory cells forming acinar patterns. (nih.gov)
  • Representative examples include the acinar cell carcinoma of the pancreas and the acinar adenocarcinoma of the prostate gland. (nih.gov)
  • Eccrine gland carcinoma encompasses a rare group of sweat gland neoplasms that can be subdivided into many different types based on a wide histological spectrum. (logicalimages.com)
  • Eccrine gland carcinoma can arise de novo in a normal sweat gland structure, or it can represent a transformation of a pre-existing benign eccrine neoplasm. (logicalimages.com)
Malignant eccrine2
  • Immunosuppressed patients may be more susceptible to developing both benign and malignant eccrine neoplasms. (logicalimages.com)
  • 13. Malignant eccrine hidradenoma. (nih.gov)
Epithelial1
  • Code Preferred Term Synonyms Definition Neoplastic Status C7419 Acanthoma A benign skin neoplasm composed of epithelial cells. (nih.gov)
Eccrine glands1
  • Two to five million eccrine glands are distributed on almost the entire skin surface, with sparing of the lips, external auditory canal, glans penis, labia minora, and clitoris. (logicalimages.com)
Eyelid2
  • 4. Rapidly Enlarging Hidradenoma of the Eyelid. (nih.gov)
  • 5. Papillary hidradenoma of the eyelid margin: clinical and immunohistochemical observations further supporting an apocrine rather than an eccrine origin. (nih.gov)
Papillary structures2
  • Microscopically, the well-demarcated nodule is seen in the dermis, consisting of complex papillary structures and 'maze-like' glands. (surgpath4u.com)
  • 1. Value of Immunohistochemistry to Differentiate Digital Papillary Adenocarcinoma From Acral Hidradenoma With Papillary Structures. (nih.gov)
Secretory1
  • It is produced by the cystic proliferation of apocrine secretory glands. (bvsalud.org)
Carcinomas2
  • Eccrine gland carcinomas can be locally invasive, but most pose a low risk for metastasis. (logicalimages.com)
  • However, research shows UVR is known to suppress sweating, which disrupts body thermoregulation, and a study analyzing TP53 mutations in 16 sweat gland carcinomas identified 3 G:C → A:T transitions at dipyrimidine sequences on the antisense strand. (medscape.com)
Dermis1
  • The authors hypothesize that this difference may be partly explained by the fact that the bulk of eccrine sweat glands lie deep in the dermis, an environment relatively protected from the sun and environmental mutagens. (medscape.com)
Occur1
  • Keratoacanthomas (KAs) are benign cutaneous neoplasms that occur in elderly patients who are frequently exposed to the sun. (medscape.com)
Pituitary1
  • Electron microscopic studies reveal giant mitochondria, a finding not present in any other type of pituitary gland adenomas. (nih.gov)
Conditions1
  • Spiroma List of cutaneous conditions List of cutaneous neoplasms associated with systemic syndromes Laws RA, English JC, Elston DM (November 1996). (wikipedia.org)
Breast1
  • 12. Giant apocrine hidradenoma of the breast. (nih.gov)