• An endangered woody shrub Rauwolfia serpentina L. Benth belongs to the Apocynaceae family holds the tremendous potentialities for massive propagation and isolation of indole alkaloids through in vitro culture. (scialert.net)
  • It is regarded as a rich source of pharmaceutically important indole alkaloids that are used as antitumor, hypotensive and antiarrhythmic agents. (supercriticalfluids.com)
  • Among the indole alkaloids, vinblastine and vincristine are currently used to treat a wide variety of neoplasms and is recommended for treatment of Hodgkin's disease, acute leukemia and choriocarcinoma, which is resistant to other types of therapy. (supercriticalfluids.com)
  • The unique antitumor activities of these indole alkaloids have resulted in a great demand for vinblastine and vincristine as anticancer agents. (supercriticalfluids.com)
  • The plant contains indole alkaloids. (medprep.info)
  • Mass spectral analysis gave a few characteristic m/z values suggesting the presence of a few known indole alkaloids, while HPLC profiling highlighted the complexity of the extract. (afpm.org.my)
  • The bark of both the species contains indole alkaloids. (indianmedicinalplants.info)
  • Plant yields more than 100 monoterpenoid indole alkaloids in different organs. (stuartxchange.org)
  • Extracts containing these terpene indole alkaloids (TIAs) can inhibit the formation and destabilize preformed fibrils of amyloid β protein (a pathological marker of Alzheimer's disease), and have been shown to improve the cognitive function of mice with Alzheimer-like symptoms. (biomedcentral.com)
  • Since the terpenoid indole alkaloids (TIAS) biosynthesis pathway is adjustable, modification of underlying substrate and enzymes concentration by biotic and abiotic elicitors are important approaches for overproduction of these metabolites. (jmp.ir)
  • 9. Hedhili S, Courdavault V, Giglioli-Guivarc'h N, Gantet P. Regulation of the terpene moiety biosynthesis of Catharanthus roseus terpene indole alkaloids. (jmp.ir)
  • Tabernanthe iboga contains indole alkaloids, the entire root containing around 1% total alkaloids. (ibogaineglobal.site)
  • 22] Dimeric alkaloids such as vincristine and vinblastine are produced by the coupling the smaller indole alkaloids vindoline and catharanthine. (scientificlib.com)
  • Lumusidines A-D, bisindole alkaloids of the macroline-macroline type, and one of the macroline-pleiocarpamine type, villalstonidine F, were isolated from the stem-bark extract of Alstonia macrophylla (Apocynaceae). (afpm.org.my)
  • Most TIAs are found in three dicotyledon plant families: Apocynaceae, Rubiaceae and Loganiaceae, and are thought to be part of a plants chemical defense against pests [ 10 ]. (biomedcentral.com)
  • Ibogaine is an indole alkaloid found in the roots of Tabernanthe iboga Apocynaceae family, a rain forest shrub that is native to equatorial Africa. (erowid.org)
  • Ibogaine: A Novel Anti-Addictive Compound A Comprehensive Literature Review By: Jonathan Freedlander Advisor: Carlo DiClemente, Ph.D. University of Maryland, Baltimore County Introduction and History Ibogaine is a naturally occurring indole alkaloid, found in a variety of African shrubs of the Tabernanthe genus (Obach, Pablo, and Mash, 1998). (mindvox.com)
  • Catharanthus roseus is a perennial species of flowering plant in the family Apocynaceae. (stuartxchange.org)
  • 7. Chen Q, Lu X, Guo X, Guo Q and Li D. Metabolomics characterization of two apocynaceae plants, Catharanthus roseus and Vinca minor, using GC-MS and LC-MS methods in combination. (jmp.ir)
  • Reserpine (an indole alkoloid) is the antihypertensive principle having tranguillizing property also. (sdach.ac.in)
  • Affinine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana. (wikipedia.org)
  • Ibogaine is an indole alkaloid found in the roots of Tabernanthe iboga Apocynaceae family, a rain forest shrub that is native to equatorial Africa. (erowid.org)
  • The Ibogaine we are discussing is an indole alkaloid that is extracted from the root barks of the Tabernanthe iboga. (phoenixrisingwellnesscenter.co)
  • Ibogaine: A Novel Anti-Addictive Compound A Comprehensive Literature Review By: Jonathan Freedlander Advisor: Carlo DiClemente, Ph.D. University of Maryland, Baltimore County Introduction and History Ibogaine is a naturally occurring indole alkaloid, found in a variety of African shrubs of the Tabernanthe genus (Obach, Pablo, and Mash, 1998). (mindvox.com)
  • 17. Metabolomics Characterization of Two Apocynaceae Plants, Catharanthus roseus and Vinca minor, Using GC-MS and LC-MS Methods in Combination. (nih.gov)