• There are three types of sweat glands that occur over the skin surface: eccrine, apocrine and apoeccrine. (biomedcentral.com)
  • Thus, appropriate classification of such sweat glands, and associated tumors, enables us to devise a specific and appropriate sweat gland tumor therapeutical plan, and also an associated precise prognosis, i.e. apocrine carcinomas are able to metastasize to regional lymph nodes and do so frequently, whereas eccrine carcinomas are typically not able to metastasize [ 4 ]. (biomedcentral.com)
  • Lymph node involvement is typically rare for eccrine carcinoma but distal metastasis is not uncommon [ 4 ]. (biomedcentral.com)
  • This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
  • Eccrine carcinoma is a quite rare malignant tumor that typically arises from a normal sweat gland and that features a rather high recurrence rate subsequent to simple excision. (biomedcentral.com)
  • Herein, we report on an unusual case of perianal eccrine carcinoma, initially presenting as a perianal abscess. (biomedcentral.com)
  • Even though eccrine carcinomas would appear to be rare, when dealing with recurrent skin tumors or recurrent perianal fistulas, the possibility of eccrine carcinoma should be considered by consulting clinicians. (biomedcentral.com)
  • Eccrine carcinoma is a rare, malignant sweat gland tumor, generally featuring a slow growth rate and a rather high local recurrence rate [ 2 ]. (biomedcentral.com)
  • Sweat gland carcinomas were first reported by Stout and Cooley in 1951 with the observation that, "sweat gland carcinoma often developed at the site of pre-existing nodules of longstanding and they have a propensity to metastasize" [ 2 ]. (biomedcentral.com)
  • Appropriate sweat gland carcinoma classification is clearly important since each of the specific sweat gland carcinomas features its own characteristic biological behavior [ 4 ]. (biomedcentral.com)
  • Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
  • breast carcinoma, sweat gland carcinoma, skin cancer. (bvsalud.org)
  • The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)
  • Given its rather poor response to adjuvant therapy, wide excision of the lesion with tumor-free margins may offer a reasonable chance for long-term control of this neoplasm. (biomedcentral.com)
  • Such sweat glands are distributed over the entire body skin surface, with the greatest density being found on the palms of the hands and soles of the feet [ 1 ]. (biomedcentral.com)
  • This is a unique case due to the low frequency 2 , the atypical clinical history, but mainly the difficult histopathological differential diagnosis and immunohistochemical evaluation among these neoplasms. (bvsalud.org)
  • The first large study pertaining to the classification of sweat gland carcinomas was published in 1968 by Berg and McDivitt [ 3 ]. (biomedcentral.com)
  • Malignant C27273 Poroma Eccrine Poroma A benign, well circumscribed sweat gland neoplasm with eccrine or apocrine differentiation. (nih.gov)
  • It most often develops as a form of degenerative progression from a benign ECCRINE POROMA . (nih.gov)
  • Endocervical Carcinoma An adenocarcinoma characterized by the presence of malignant glandular epithelium resembling the endocervical epithelium. (nih.gov)
  • Eccrine gland carcinoma encompasses a rare group of sweat gland neoplasms that can be subdivided into many different types based on a wide histological spectrum. (logicalimages.com)
  • Eccrine gland carcinoma can arise de novo in a normal sweat gland structure, or it can represent a transformation of a pre-existing benign eccrine neoplasm. (logicalimages.com)
  • Unlike squamous cell carcinoma and basal cell carcinoma, there is not a firmly established role for ultraviolet (UV) radiation and environmental toxins in eccrine carcinoma. (logicalimages.com)
  • However, some studies have entertained a causal role for both UV radiation and genetics in microcystic adnexal carcinoma, one type of eccrine carcinoma. (logicalimages.com)
  • Some of the other adnexal carcinomas with presumed eccrine derivation include adenoid cystic carcinoma, mucinous carcinoma , digital papillary adenocarcinoma, and microcystic adnexal carcinoma (MAC). (logicalimages.com)
  • Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
  • breast carcinoma, sweat gland carcinoma, skin cancer. (bvsalud.org)
  • Immunosuppressed patients may be more susceptible to developing both benign and malignant eccrine neoplasms. (logicalimages.com)
  • The differential diagnosis for these lesions is broad and includes a variety of benign and malignant lesions. (logicalimages.com)
  • Associated with a presumed malignant melanoma of the choroid. (nih.gov)
  • Keratoacanthomas (KAs) are benign cutaneous neoplasms that occur in elderly patients who are frequently exposed to the sun. (medscape.com)
  • Multiple KAs should raise suspicion of Muir-Torre syndrome, a genodermatosis with a defect in the MSH mismatch repair gene that is associated with sebaceous neoplasms and gastrointestinal cancers. (medscape.com)
  • Malignant C4258 Pleomorphic Rhabdomyosarcoma An aggressive malignant mesenchymal neoplasm with skeletal muscle differentiation, occurring in adults and rarely in children. (nih.gov)
  • Patients with the inherited form appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma. (nih.gov)
  • Viruses have been frequently identified in several human neoplasms, but the etiological role of these viruses in some tumors is still a matter of controversy. (bvsalud.org)
  • As with all tumors, whether benign or malignant, identification of the cell or cell layer of origin is of the utmost importance. (medscape.com)
  • Neutrophilic eccrine hidradenitis (NEH) is a neutrophilic dermatosis primarily affecting the eccrine glands and occurs most commonly in patients undergoing chemotherapy for a malignancy. (annals.edu.sg)