• Primary mucinous carcinoma (PMC) of the skin is a rare malignant neoplasm deriving from sweat glands [ 1 ]. (cdlib.org)
  • In order of decreasing incidence, squamous cell carcinoma (SCC), basal cell carcinoma (BCC), basosquamous cell carcinoma, and melanoma account for 90% of primary malignant tumors of the hand. (medscape.com)
  • Other malignant skin lesions include dermatofibrosarcoma protuberans, Kaposi sarcoma, sweat gland tumors, and Merkel cell carcinoma. (medscape.com)
  • The malignant osseous tumors consisted of two primary lesions (an osteosarcoma and a chondrosarcoma) and two that had metastasized to the hand (one from a lung carcinoma and the other from a chondrosarcoma). (medscape.com)
  • Given these results, the authors discuss the difficulty in diagnosing differentiation from a primary or metastatic neoplasm of the scalp, with the resources currently available, until the conclusion that it was a primary carcinoma of the sweat gland. (bvsalud.org)
  • breast carcinoma, sweat gland carcinoma, skin cancer. (bvsalud.org)
  • This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
  • The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)
  • Squamous cell carcinoma of varying degrees of differentiation is observed in 90% of patients with malignant tumors of the vulva. (med-blog.com)
  • The most common malignant neoplasm arising in this disorder is basal cell carcinoma. (medscape.com)
  • Studies indicate that the development of basal cell carcinoma or any other malignant neoplasm is very rare. (medscape.com)
  • Other benign and malignant tumors include syringocystadenoma papilliferum arising from the apocrine sweat glands, keratoacanthoma , apocrine cystadenoma , leiomyoma , and sebaceous cell carcinoma. (medscape.com)
  • This was due to misdiagnosis of basal cell carcinomas that were in fact trichoblastomas (benign form of neoplasm that look like basal cell carcinoma histologically). (medscape.com)
  • Eccrine carcinoma is a quite rare malignant tumor that typically arises from a normal sweat gland and that features a rather high recurrence rate subsequent to simple excision. (biomedcentral.com)
  • Eccrine carcinoma is a rare, malignant sweat gland tumor, generally featuring a slow growth rate and a rather high local recurrence rate [ 2 ]. (biomedcentral.com)
  • Sweat gland carcinomas were first reported by Stout and Cooley in 1951 with the observation that, "sweat gland carcinoma often developed at the site of pre-existing nodules of longstanding and they have a propensity to metastasize" [ 2 ]. (biomedcentral.com)
  • Appropriate sweat gland carcinoma classification is clearly important since each of the specific sweat gland carcinomas features its own characteristic biological behavior [ 4 ]. (biomedcentral.com)
  • We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. (ijpmonline.org)
  • Such features are seen in eosinophilic chromophobe carcinoma, a malignant tumor that can mimic oncocytoma. (promisekit.org)
  • A rare adnexal carcinoma that is histopathologically identical to homologous lesions in the salivary gland and breast. (nih.gov)
  • Secretory Carcinoma of the Eyelid Arising in an Adnexal Gland. (nih.gov)
  • however, a high index of suspicion is always imperative to avoid the misdiagnosis of a malignant tumor (see image below). (medscape.com)
  • We report a case of 68-year-old woman who developed this very uncommon malignant tumor. (hindawi.com)
  • Given its rather poor response to adjuvant therapy, wide excision of the lesion with tumor-free margins may offer a reasonable chance for long-term control of this neoplasm. (biomedcentral.com)
  • Thus, appropriate classification of such sweat glands, and associated tumors, enables us to devise a specific and appropriate sweat gland tumor therapeutical plan, and also an associated precise prognosis, i.e. apocrine carcinomas are able to metastasize to regional lymph nodes and do so frequently, whereas eccrine carcinomas are typically not able to metastasize [ 4 ]. (biomedcentral.com)
  • When two distinct neoplasms are located adjacent to the same cutaneous site, the phenomenon is commonly referred to as a collision tumor [ 1 , 2 ]. (e-acfs.org)
  • 1 First described in 1956, poroma was originally identified as a tumor originating from the eccrine sweat gland. (clinicaladvisor.com)
  • Nonfunctioning neuroendocrine neoplasms can still cause symptoms relating to tumor size and location such as obstruction or internal bleeding. (rarediseases.org)
  • For those that consider this entity to be a tumor, there is further disagreement whether this is a tumor of epidermal, pilar, or sweat gland origin. (statpearls.com)
  • 4] Intraepidermal Eccrine Adenocarcinoma (IEA) is classified with several other lesions that share similar pathological form, including: eccrine acrospiroma, eccrine porocarcinoma, malignant eccrine poroma and malignant hidroacanthoma simplex, among others. (faoj.org)
  • The high proportion of mitotic cells and resemblance to well-differentiated adenocarcinoma of the large intestine suggested that this neoplasm was adenocarcinoma rather than adenoma. (hindawi.com)
  • Pancreatic cancer as a general term usually refers to pancreatic adenocarcinoma, an aggressive malignant cancer with a poor prognosis. (rarediseases.org)
  • Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. (ijpmonline.org)
  • Dentists are involved with aspects of salivary gland function in several ways, such as diagnosing problems involving the major and minor salivary glands, in the management of oral dryness associated with salivary problems, in the treatment of caries and periodontal disease resulting from decreased salivary flow, and in controlling salivation during restorative procedures. (medscape.com)
  • Intraepidermal Eccrine Adenocarcinomas (IEA) are rare malignant tumors derived from the eccrine sweat glands of the skin. (faoj.org)
  • Primary malignant neoplasms of the sweat glands are rare, constituting less than 1% of all primary malignant skin lesions 1 . (bvsalud.org)
  • A benign form of IEA is eccrine acrospiroma, which can transform to a malignant form, especially in inveterate lesions. (faoj.org)
  • Malignant transformation occurs in 10-15% of lesions in some series, although others suggest that this rate may be much lower. (medscape.com)
  • the conspicuity of these lesions can be reduced due to a combination of the high density of the parotid gland and weak enhancement of the lesion. (promisekit.org)
  • [7] [8] Although malignant features developed in these lesions, there are no reports of recurrence or metastasis. (statpearls.com)
  • Parotid gland oncocytoma is an uncommon, benign salivary neoplasm composed of mitochondria-rich epithelial cells called oncocytes. (promisekit.org)
  • Ameloblastoma is a benign epithelial odontogenic neoplasm which is common amongst the Yoruba ethinc group. (bvsalud.org)
  • Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis. (wikipedia.org)
  • Poroma is a benign adnexal neoplasm of the intraepidermal portion of the sweat gland duct, called the acrosyringium . (clinicaladvisor.com)
  • Affected individuals are also at increased risk of developing tumors in tissues other than skin appendages, particularly benign or malignant tumors of the salivary glands. (medlineplus.gov)
  • Malignant melanoma microstaging: pitfalls and perspectives. (markahurt.com)
  • Malignant melanoma microstaging. (markahurt.com)
  • Malignant melanoma microstaging: historical perspective, practical applications, and potential pitfalls. (markahurt.com)
  • Clinical tumors are characterized by an extremely malignant course in cases where the phasing of lymphogenous metastasis is impaired. (med-blog.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • Malignant prostatic mass with extracapsular extension on right side with pelvic lymphadenopathy and extensive bony metastasis. (hpathy.com)
  • In 1895, Jadassohn first described nevus sebaceous (see the image below), a circumscribed hamartomatous lesion predominantly composed of sebaceous glands. (medscape.com)
  • Porocarcinoma (PC) is a rare type of skin cancer that typically arises from sweat glands. (e-acfs.org)
  • Rapid enlargement, ulceration, spontaneous bleeding, and pain are signs that the lesion may be developing into its malignant counterpart, porocarcinoma. (clinicaladvisor.com)
  • The thyroid gland weighs, on average, 15 g, and is composed of two lateral lobes that extend to the sides of the larynx to very close to the midline of the thyroid cartilage, and that are joined by an isthmus that pass in front of the trachea. (teknon.es)
  • Multinodular goiter (MNG) is the most common disorder of the thyroid gland. (intechopen.com)
  • It starts as a diffuse enlargement of the thyroid gland and ends in a nodular enlarged thyroid. (intechopen.com)
  • Goiter is the enlargement of the thyroid gland which can be due to a variety of conditions. (intechopen.com)
  • Nodular goiter is one of the most common endocrine disorders affecting the thyroid gland. (intechopen.com)
  • It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (lookformedical.com)
  • Tumors or cancer of the THYROID GLAND. (lookformedical.com)
  • The pituitary gland produces thyroid stimulating hormone (TSH) that goes into the blood stream to activate thyroid cells, which then secrete T3 and T4 into the peripheral tissues. (cdc.gov)
  • The thyroid gland secretes about 8 micrograms of T3/day, but 40 micrograms of T3 is made overall. (cdc.gov)
  • The incidence of secondary neoplasms was statistically related to age and anatomic site (P (aad.org)
  • While malignant hand tumors are relatively uncommon, the incidence of metastatic tumors is exceedingly rare. (medscape.com)
  • In Russia, in the structure of the incidence of malignant neoplasms of the female genital organs, vulvar cancer is from 3 to 8% and takes fourth place. (med-blog.com)
  • An increased incidence of glioma in the brain and malignant schwannoma in the heart was found in the US National Toxicology Program (NTP) study on rats and mice. (spandidos-publications.com)
  • Adrenocortical adenoma  encapsulated, expansile, yellow tumors, lipid-rich cells, adjacent adrenal cortex and contralateral adrenal glands are atrophic b/c of suppression of endogenous ACTH by high cortisol levels. (docsbay.net)
  • aldosterone secreting adenoma in one adrenal gland. (docsbay.net)
  • were the first to describe tumors exhibiting features of the epidermal sweat duct. (faoj.org)
  • A statistically significant increased risk for ipsilateral use of mobile phones, the same side of the brain as the phone was used, was published for malignant brain tumors ( 4 ) and vestibular schwannoma ( 5 ). (spandidos-publications.com)
  • Rarely, malignant eccrine poromas and apocrine carcinomas have been reported to result in widespread metastases and death. (medscape.com)
  • The first large study pertaining to the classification of sweat gland carcinomas was published in 1968 by Berg and McDivitt [ 3 ]. (biomedcentral.com)
  • Unfortunately, as far as we are aware, sweat gland carcinomas are often under diagnosed or misdiagnosed due to their clinical rarity [ 8 ]. (biomedcentral.com)
  • Metastases associated with adrenal gland are more prominent in the determination of preexisting neoplasms and underlying adrenal insufficiency. (targetwoman.com)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • The sublingual glands, under the tongue, produce about 5% of the total oral saliva. (medscape.com)
  • [ 7 ] age-related decline in saliva output was found to occur in the stimulated parotid, unstimulated submandibular/sublingual, and stimulated submandibular/sublingual glands. (medscape.com)
  • Additional research suggests that changes may occur in the viscoelasticity of saliva with aging, particularly in saliva produced by the submandibular and sublingual glands. (medscape.com)
  • Sublingual fossa: for sublingual glands 4. (slideshare.net)
  • Bone and soft tissue malignancies of the hand are much less common than cutaneous malignant tumors. (medscape.com)
  • Malignant bone tumors that occur in the hand include chondrosarcomas, osteogenic sarcomas, and Ewing sarcoma. (medscape.com)
  • There are three types of sweat glands that occur over the skin surface: eccrine, apocrine and apoeccrine. (biomedcentral.com)
  • These tumors occur predominantly on one adrenal gland as an unilateral condition. (targetwoman.com)
  • Various malignant skin tumors have been reported to co-occur with BCC at one site [ 3 ]. (e-acfs.org)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • In the parotid gland, oncocytomas most commonly occur in adults in their sixth to eighth decades, with no sex predilection. (promisekit.org)
  • Given the low risk of malignant transformation in children, clinical follow-up is considered to be a safe alternative to prophylactic surgical excision. (medscape.com)
  • They have some different differentiation (G1-3), but all of them have the potential for malignant transformation. (rarediseases.org)
  • It begins in blood cells that have undergone a malignant transformation. (mediflam.com)
  • Adrenocortical tumors may be benign or malignant. (docsbay.net)
  • The authors concluded: "Our study confirms that most of the secondary neoplasms arising in association with nevus sebaceus are benign. (aad.org)
  • The medical importance of a solitary nevus sebaceus relates to the description of both benign change and, in some cases, malignant neoplastic change. (medscape.com)
  • The development of secondary malignant neoplasms within the nevus sebaceus is rare and occurs almost exclusively in adults. (medscape.com)
  • Jaqueti G, Requena L, Sanchez Yus E. Trichoblastoma is the most common neoplasm developed in nevus sebaceus of Jadassohn: a clinicopathologic study of a series of 155 cases. (medscape.com)
  • This is a unique case due to the low frequency 2 , the atypical clinical history, but mainly the difficult histopathological differential diagnosis and immunohistochemical evaluation among these neoplasms. (bvsalud.org)
  • METHODS: Gene expression profiles and clinical information of individuals diagnosed with prevalent malignant tumors were obtained from the TCGA database. (bvsalud.org)
  • A complete history and physical examination with special attention to the affected limb, supplemented by radiologic studies and biopsies, are fundamental to obtaining the correct diagnosis of and and administering the proper treatment for malignant hand tumors. (medscape.com)
  • It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease. (ijpmonline.org)
  • [ 1 ] This article reviews basic salivary anatomy and physiology, several important diseases affecting the glands, salivary constituents as measures of health, trends in diagnosis, and the management of xerostomia and drooling. (medscape.com)
  • Neutrophilic eccrine hidradenitis (NEH) is a neutrophilic dermatosis primarily affecting the eccrine glands and occurs most commonly in patients undergoing chemotherapy for a malignancy. (annals.edu.sg)
  • Additional benign neoplasms such as trichoepithelioma (8), tubular apocrine adenomas (9), sebaceomas (1), and others have been reported within NS. (aad.org)
  • Primary malignant tumors are subdivided further into skin tumors, musculoskeletal tumors, and soft tissue tumors. (medscape.com)
  • The adrenal gland is located on the superior portion of the kidney. (targetwoman.com)
  • Many metabolic pathways depend upon the adrenal gland functionality through its hormone production. (targetwoman.com)
  • Some of the significant hormones produced by the adrenal gland include aldosterone, cortisol, sex hormones and adrenaline. (targetwoman.com)
  • The adrenal gland comprises two distinctive regions cortex and medulla respectively. (targetwoman.com)
  • Each region of the adrenal gland produces different kinds of hormones. (targetwoman.com)
  • Adrenal Pheochromocytoma is a condition in which tumors are formed on the adrenal gland. (targetwoman.com)
  • Tumors associated with the adrenal cortex fall into the functional category whereas the remaining part of the adrenal gland secreting mixed hormones such as sex hormones and aldosterone fall under the nonfunctional category. (targetwoman.com)
  • There was evidence of perineural invasion and the synaptophysin (marker protein for neuroendocrine cells and neoplasms) was focally positive. (hpathy.com)
  • Pancreatic neuroendocrine neoplasms (pNENs) are an increasingly common group of malignancies that arise within the endocrine tissue of the pancreas. (rarediseases.org)
  • The parotids produce the most fluid saliva, as they are composed of serous acini, with the sublingual gland producing mucus from mucous acini. (medscape.com)
  • The minor glands are primarily mucous producing, except those under the tongue, which produce serous fluid. (medscape.com)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • In some countries, maxillofacial surgeons are also involved in the primary treatment of neoplasm involving the salivary glands. (medscape.com)