• Higher vitamin D status does not play a protective role in risk of NHL or common NHL subtypes. (nih.gov)
  • Similarly, there was no increased risk for developing any of the 3 most common specific subtypes, i.e., diffuse large B-cell lymphoma, follicular lymphoma, or B-cell chronic lymphocytic leukemia. (medpagetoday.com)
  • Non-Hodgkin lymphoma is a type of blood cancer that includes a diverse grouping of around 40 different subtypes affecting cells of the immune system called lymphocytes. (edu.au)
  • The strongest and most consistent evidence is with occupational exposure like pesticides and solvents, and that has not been studied particularly well in the past, because usually all non-Hodgkin lymphoma subtypes have been assessed together. (edu.au)
  • There are more than 50 subtypes of non-Hodgkin lymphoma. (cancer.ie)
  • The familial risk of lymphoma is elevated for multiple lymphoma subtypes, suggesting a shared genetic cause. (wikipedia.org)
  • The World Health Organization (WHO) divides Hodgkin lymphoma into two main subtypes. (lls.org)
  • There are two main subtypes: anaplastic large cell lymphoma (ALCL) and diffuse large B-cell lymphoma (DLBCL). (acco.org)
  • Although the evidence is not consistent, epidemiologic studies have suggested that taller adult height may be associated with an increased risk of some non-Hodgkin lymphoma (NHL) subtypes. (ox.ac.uk)
  • We used logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI) for association between genetically determined height and the risk of four NHL subtypes in each GWAS and then used fixed-effect meta-analysis to combine subtype results across studies. (ox.ac.uk)
  • Analysis of circulating tumor DNA by targeted ultra-deep sequencing across various non-Hodgkin lymphoma subtypes. (cdc.gov)
  • Mantle cell lymphoma represents approximately six percent of all cases of non-Hodgkin's lymphoma, the most common hematological malignancy worldwide. (scitechdaily.com)
  • Only a professional will be able to accurately assess and diagnose possible cases of non-Hodgkin's lymphoma and develop a treatment plan accordingly. (pintas.com)
  • Most cancers are the result of many risk factors. (cancer.ca)
  • Risk of some cancers, such as breast and colon cancers, is lower in people who are physically active, and these researchers sought evidence of a similar association for NHL. (oncologynurseadvisor.com)
  • We investigated the risk of lymphomas, hemolymphopoietic (HLP) cancers (including lymphomas), and non-HLP cancers in first-degree relatives of non-Hodgkin's lymphoma (NHL) cases in an Italian case-control study on 225 patients (median age, 59 years) with a new diagnosis of NHL and 504 hospital controls (median age, 63 years), admitted for a wide spectrum of acute, nonneoplastic, nonimmune conditions. (aacrjournals.org)
  • The HR of relatives of NHL cases, compared with relatives of controls, was 4.5 (95% CI, 1.1-18.8) for lymphomas, 3.5 (95% CI, 1.5-7.4) for HLP cancers, 1.6 (95% CI, 1.3-2.0) for all cancers, and 1.0 (95% CI, 0.9-1.1) for all causes of deaths. (aacrjournals.org)
  • The OR was also elevated for all cancer sites (OR, 1.7 95% CI, 1.2-2.4) and the risk increased with the number of affected relatives also when HLP cancers were excluded. (aacrjournals.org)
  • For most epithelial cancers, first-degree relatives of affected individuals have a 2- to 5-fold increased risk of developing a cancer at the same site ( 1, 2 ). (aacrjournals.org)
  • Lymphomas are cancers that develop in the lymphatic system, an important part of the immune system that helps protect the body against infection and disease. (medicalnewstoday.com)
  • Lymphomas are cancers of the lymphatic system. (epnet.com)
  • These cancers are different from Hodgkin lymphoma . (epnet.com)
  • Although treatment is very effective, patients are at a high risk for late treatment effects, including cardiac and thyroid conditions, lung disease, second cancers, infertility, and psychosocial problems. (medscape.com)
  • Non-Hodgkin's lymphomas, like other cancers, are diseases of the body's cells. (digitalnaturopath.com)
  • Together with Hodgkin lymphoma, it ranks in the top 10 most common cancers in Australia. (edu.au)
  • Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. (wikipedia.org)
  • Radiation and some chemotherapy, however, increase the risk of other cancers, heart disease, or nerve problems over the subsequent decades. (wikipedia.org)
  • The Centers for Disease Control and Prevention (CDC) included certain types of non-Hodgkin lymphoma as AIDS-defining cancers in 1987. (wikipedia.org)
  • See Second Cancers After Hodgkin Lymphoma for more on this. (cancer.org)
  • Non-Hodgkin Lymphoma accounts for about 5% of all childhood cancers (Hodgkin Lymphoma accounts for around 3% of all childhood cancers). (acco.org)
  • For most children with NHL, this type of cancer is unlikely to return once a child has been "cancer free" for five years (although this does not address the risk of secondary cancers stemming from the original cancer treatment). (acco.org)
  • Burkitt lymphoma is one of the fastest-growing cancers and must be treated very aggressively. (acco.org)
  • Here are examples of study results looking at the effectiveness of pembrolizumab (Keytruda) in three different cancers: advanced melanoma, non-small cell lung cancer and Hodgkin lymphoma. (drugs.com)
  • Statins have been associated with a significantly lower risk of breast (8), colorectal (9), and lymph cancers (10-12) in several observational studies (10,13). (cdc.gov)
  • Overview of Lymphoma Lymphomas are cancers of lymphocytes, which reside in the lymphatic system and in blood-forming organs. (msdmanuals.com)
  • Lymphomas are cancers of a specific type of white blood cells known as lymphocytes. (msdmanuals.com)
  • Non-Hodgkin Lymphomas Non-Hodgkin lymphomas are a diverse group of cancers of types of white blood cell called lymphocytes. (msdmanuals.com)
  • Previous studies have found elevated risks of several types of cancers in firefighters. (cdc.gov)
  • Known causes of haematological al y have not indicated an increased In 1974, IARC concluded that studies cancers in humans are ionizing ra- risk of AML. (who.int)
  • The risk of relapse is at its highest during the first two or three years of diagnosis," says Dr Ingrid Glimelius , oncologist at Akademiska Hospital in Uppsala and a researcher affiliated to both Karolinska Institutet's Department of Medicine (Solna) and the Department of Immunology, Genetics and Pathology at Uppsala University. (ki.se)
  • Improved methods to assess higher risk at diagnosis using quantitative PET metrics, such as metabolic tumor volume and total lesion glycolysis, and incorporation of emerging biomarkers may further refine patient selection for more intensive upfront therapy. (ashpublications.org)
  • The application of antigen receptor gene rearrangement of BIOMED-2 in the pathologic diagnosis of 348 cases with non-Hodgkin lymphoma in a single institution in Southwest of China. (cdc.gov)
  • The LEAF study, which aims to recruit 2,400 Australians, is the first internationally to examine both the genetic and environmental risk factors for one of the most common forms of the disease , follicular lymphoma. (edu.au)
  • Rates of follicular lymphoma are continuing to increase in Australia and internationally, while rates of some other non-Hodgkin lymphomas have plateaued. (edu.au)
  • But because we don't know what causes follicular lymphoma, we can't implement any targeted prevention programs," Associate Professor Vajdic said. (edu.au)
  • The five-year study spans NSW and Victoria and will recruit people diagnosed with follicular lymphoma and either their sibling or partner. (edu.au)
  • So that's why we are focusing on follicular lymphoma alone and asking questions about people's occupational exposures, as well as measuring chemical levels in their blood," Associate Professor Vajdic said. (edu.au)
  • Follicular lymphoma international prognostic index. (medscape.com)
  • 0.0001), but not for follicular lymphoma. (johnshopkins.edu)
  • HHV-8: associated with primary effusion lymphoma, multicentric Castleman disease. (wikipedia.org)
  • VOR (300 or 400 mg) was given orally on days 1 to 5 with each cycle of R-EPOCH for 10 high-risk patients with diffuse large B-cell lymphoma (1 EBV + ), 1 EBV + /HHV-8 + primary effusion lymphoma, and 1 unclassifiable NHL. (wustl.edu)
  • More than 80% of patients with advanced-stage Hodgkin lymphoma are now cured with contemporary treatment approaches. (ashpublications.org)
  • Patients with advanced-stage Hodgkin lymphoma (HL) have excellent outcomes with contemporary treatment approaches. (ashpublications.org)
  • Now that there is an overall survival benefit, I think, really, the field has shifted and I would say most providers are offering brentuximab AVD for any patient with advanced-stage Hodgkin lymphoma, but especially this kind of high-risk patient. (reachmd.com)
  • And so just to summarize, I think in this patient with high-risk advanced-stage Hodgkin lymphoma, I would aim to use brentuximab vedotin [BV] combined with AVD. (reachmd.com)
  • In total, 254 of 399 (63.7%) patients with AIDS-related lymphomas reached a complete remission with their first-line chemotherapy. (uni-koeln.de)
  • Several factors were independently associated with a higher relapse rate, including an unclassifiable histology, a stage III or IV according to the Ann Arbor Staging System, no concomitant combined antiretroviral therapy during chemotherapy and R-CHOP-based compared to more intensive chemotherapy regimens in Burkitt lymphomas. (uni-koeln.de)
  • These data provide further evidence for the use of concomitant combined antiretroviral therapy during chemotherapy and a benefit from more intensive chemotherapy regimens in Burkitt lymphomas. (uni-koeln.de)
  • those with favorable risk disease typically receive two to four cycles of multi-agent chemotherapy with low-dose IFRT, whereas those with higher-risk disease receive more intensive chemotherapy before IFRT. (ices.on.ca)
  • Background: specialized studies on hepatitis B virus (HBV) infection and B-NHL (B-cell Non-Hodgkin's Lymphoma) are limited, as well as prophylactic antiviral therapy for B-NHL patients with HBV infection who are receiving anticancer chemotherapy. (scirp.org)
  • Based on results of the ECHELON-1 trial, the Food and Drug Administration approved BV in combination with adriamycin, vinblastine, and dacarbazine chemotherapy for stage III to IV Hodgkin lymphoma. (ashpublications.org)
  • According to a new, population-based analysis of the entire Netherlands population, published recently in the International Journal of Epidemiology , a history of Q fever was not associated with an increased risk of mature B-cell non-Hodgkin lymphoma (NHL). (medpagetoday.com)
  • We know that a suppressed immune system or certain inflammatory conditions increase the risk of developing Hodgkin lymphoma," says researcher Caroline Weibull, biostatistician and doctoral student at Karolinska Institutet's Department of Medical Epidemiology and Biostatistics , "and since pregnancy affects the immune system, we wanted to see if there was a statistical correlation between pregnancy and risk of relapse. (ki.se)
  • Methods: We obtained original data from nine case-control studies from the USA, UK, Sweden, and Italy in the International Lymphoma Epidemiology Consortium (InterLymph), yielding a pooled study population of 15175 individuals (6492 cases and 8683 controls). (elsevierpure.com)
  • Non-Hodgkin's Lymphoma (NHL) - Market Insights, Epidemiology and Market Size Forecast-2020, report provides an insight on the forecast of a indication over a period of time which helps an organization to better understand the business development strategies from present and futuristic point of view. (openpr.com)
  • Non-Hodgkin's Lymphoma (NHL) - Market Insights, Epidemiology and Market Size Forecast-2020, provides clients with the detailed insights into epidemiology and market forecast of the indication in these countries. (openpr.com)
  • We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph). (johnshopkins.edu)
  • If you have swollen lymph nodes or other symptoms that suggest non-Hodgkin's lymphoma, your doctor will help you find out whether they are from cancer or some other cause. (daviddarling.info)
  • What are the symptoms of non-Hodgkin lymphoma in a child? (uhhospitals.org)
  • The signs and symptoms of non-Hodgkin lymphoma vary depending upon its location within the body. (wikipedia.org)
  • Knowing if you have any B symptoms will help your doctor to stage the lymphoma and plan your treatment. (macmillan.org.uk)
  • What Are the Symptoms of Hodgkin's Lymphoma? (carle.org)
  • Treatment is dependent on many factors, most importantly the type of lymphoma diagnosed, followed by the stage of the cancer, the patient's age and health status, and how symptoms have affected the body. (rxwiki.com)
  • These possible causes and associations with at least some forms of NHL include: Infectious agents: Epstein-Barr virus: associated with Burkitt's lymphoma, follicular dendritic cell sarcoma, extranodal NK-T-cell lymphoma and diffuse large B-cell lymphoma. (wikipedia.org)
  • Bone trauma and microfractures associated with diffuse large B-cell lymphoma originating in bone marrow. (wikipedia.org)
  • Non-Hodgkin Lymphoma (NHL) is an aggressive and diffuse type of cancer that grows within a child's immune system, specifically within a type of white blood cell known as a lymphocyte. (acco.org)
  • Specifically, in patients with diffuse large B‐cell lymphoma, of whom 91.8% had received rituximab, a history of B‐cell-mediated AIDs was associated with shorter relapse‐free survival and overall survival, HRadj = 8.34 (CI, 3.01‐ 23.1) and HRadj = 3.83 (CI, 1.20‐12.3), respectively. (alquds.edu)
  • The interleukin 10 (IL10) -3575T→A polymorphism was also associated with increased risk of non-Hodgkin lymphoma (p for trend=0.02), again particularly for diffuse large B-cell lymphoma (p for trend=0.006). (johnshopkins.edu)
  • For individuals homozygous for the TNF -308A allele and carrying at least one IL10 -3575A allele, risk of diffuse large B-cell lymphoma doubled (2.13 [1.37-3.32], p=0.00083). (johnshopkins.edu)
  • Diffuse Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma: Genetic Classification and Its Implications for Prognosis and Treatment. (cdc.gov)
  • Circulating tumor DNA: clinical roles in diffuse large B cell lymphoma. (cdc.gov)
  • The EC granted Cell Therapeutics' Pixuvri® (pixantrone) conditional marketing authorization for use as monotherapy in the treatment of adult patients with multiply relapsed or refractory aggressive non-Hodgkin B-cell lymphomas (NHL). (genengnews.com)
  • Hodgkin lymphoma is an uncommon cancer that develops in the lymphatic system, which is a network of vessels and glands spread throughout your body. (checkbiotech.org)
  • Hodgkin lymphoma (HL) is an uncommon type of cancer affecting the lymphatic system. (medicalnewstoday.com)
  • Non-Hodgkin's lymphoma (also called NHL) is cancer that begins in the lymphatic system . (daviddarling.info)
  • Non-Hodgkin's lymphomas are a type of cancer of the lymphatic system . (digitalnaturopath.com)
  • Non-Hodgkin's lymphoma (NHL) is a cancer that affects the lymphatic system, an intricate part of your immune system. (pintas.com)
  • A new class of drugs that inhibits a "master switch" involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai. (scitechdaily.com)
  • Some previous studies have found an association between mature B-cell lymphoma and Q fever, but others have not. (medpagetoday.com)
  • The SOX 11 protein, which is expressed in up to 90 percent of mantle cell lymphoma patients, is an attractive target for therapy," said senior author Samir Parekh, MD, Professor of Medicine (Hematology and Medical Oncology), Icahn School of Medicine at Mount Sinai. (scitechdaily.com)
  • One in particular showed in ex vivo laboratory studies (done on human cells outside the body) anti-MCL cytotoxicity and inhibition of phosphorylation of BTK, which is part of a signaling cascade that triggers the malignant transformation of B lymphocyte cells into mantle cell lymphoma. (scitechdaily.com)
  • Human T-cell leukemia virus: associated with adult T-cell lymphoma. (wikipedia.org)
  • Serum Levels of the Chemokine CXCL13, Genetic Variation in CXCL13 and Its Receptor CXCR5, and HIV-Associated Non-Hodgkin B-Cell Lymphoma Risk. (medscape.com)
  • In children, there are three distinct types of NHL: Lymphoblastic lymphoma (LBL), Burkitt lymphoma (also called small, non-cleaved cell lymphoma), and large cell lymphomas. (acco.org)
  • Beyond confirming the well‐known association between AIDs and B‐NHL, we found that AID is an adverse prognostic factor in B‐cell lymphoma, associated with a shortened time to relapse, suggesting that there are specific therapeutic challenges in the subgroup of patients suffering from both these diseases. (alquds.edu)
  • High grade B-cell lymphoma with MYC, BCL2 and/or BCL6 rearrangements: unraveling the genetic landscape of a rare aggressive subtype of non-Hodgkin lymphoma. (cdc.gov)
  • Clinicopathological and molecular genomic features of monomorphic epitheliotropic intestinal T-cell lymphoma in the Chinese population: a study of 20 cases. (cdc.gov)
  • Doctors subdivide lymphomas into Hodgkin and non-Hodgkin types depending on the type of lymphocyte they affect. (medicalnewstoday.com)
  • Nodular lymphocyte-predominant Hodgkin lymphoma is characterized by the presence of lymphocyte-predominant cells, sometimes termed "popcorn cells," which are a variant of Reed-Sternberg cells. (lls.org)
  • Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) affects about 5 percent of Hodgkin lymphoma patients. (lls.org)
  • The Leukemia & Lymphoma Society® (LLS) is a global leader in the fight against blood cancer. (lls.org)
  • The Leukemia & Lymphoma Society is a 501(c)(3) organization, and all monetary donations are tax deductible to the fullest extent allowed by tax laws. (lls.org)
  • Adolescent and young adult (AYA) survivors of Hodgkin's lymphoma are at high risk for long-term and late effects related to their treatment. (medscape.com)
  • They identified 354 Hodgkin's lymphoma survivors, who were diagnosed between the ages of 15 and 39 years, from an integrated healthcare system and examined use of posttreatment services. (medscape.com)
  • In her discussion of the paper, Merry-Jennifer Markham, MD, an associate professor of medicine at the University of Florida, Gainesville, pointed out that survivorship care is crucial in the AYA population of Hodgkin's lymphoma survivors, because most of them have long lives ahead of them. (medscape.com)
  • Risk of second primary malignancies among cancer survivors in the United States, 1992 through 2008. (medscape.com)
  • The research uncovered a four- to seven-fold higher risk of coronary heart disease or heart failure in these Hodgkin's survivors compared to people who had never had the disease. (ehealth-news.com)
  • Family History of Breast Cancer Associated with Breast Cancer in Survivors of Hodgkin Lymphoma. (cdc.gov)
  • People who take these drugs for other conditions, such as rheumatoid arthritis, lupus or inflammatory bowel disease, also have a higher risk of developing NHL. (cancer.ca)
  • Although research to date is not sufficient to confidently state that vigorous physical activity can reduce risk for NHL, these findings indicate that vigorous physical activity is beneficial in terms of risk for this disease. (oncologynurseadvisor.com)
  • Age: Although non-Hodgkin's lymphoma can occur in young people, the chance of developing this disease goes up with age. (daviddarling.info)
  • People who work with herbicides or certain other chemicals may be at increased risk of this disease. (daviddarling.info)
  • OBJECTIVE: To assess the risk of HL associated with allergic disease (asthma, eczema and allergic rhinitis) and corticosteroid use. (ucl.ac.uk)
  • one is called Hodgkin's disease and the other is called non-Hodgkin's lymphoma. (digitalnaturopath.com)
  • These larger cells are more likely to be faster growing and signal your disease is becoming more like a high-grade lymphoma. (cancer.ie)
  • Risk of lymphoproliferative malignancy in relation to small intestinal histopathology among patients with celiac disease. (medscape.com)
  • The LLS mission: Cure leukemia, lymphoma, Hodgkin disease and myeloma, and improve the quality of life of patients and their families. (lls.org)
  • A risk factor is anything that affects your chance of getting a disease such as cancer. (cancer.org)
  • Clinical manifestations and radiologic findings in the course of disease in a 23-year-old woman with disseminated M. genavense infection preceding Hodgkin lymphoma, Germany. (cdc.gov)
  • Non-Hodgkin lymphomas (NHL) represent a varied group of diseases distinguished by the features of the cancerous cells with each disease type. (rxwiki.com)
  • One type is Hodgkin disease . (medlineplus.gov)
  • This Public Health Statement summarizes the Agency for Toxic Substances and Disease Registry's (ATSDR) findings on tetrachloroethylene, including chemical characteristics, exposure risks, possible health effects from exposure, and ways to limit exposure. (cdc.gov)
  • Burkitt lymphoma accounts for about 40% of all NHL diagnoses in the United States. (acco.org)
  • Scholars@Duke publication: Dose-intense cyclophosphamide and etoposide for patients with refractory or high-risk non-Hodgkin's lymphoma. (duke.edu)
  • A retrospective review was performed on the toxicity and response to one cycle of dose-intense cyclophosphamide/etoposide, followed by consolidation in patients with refractory or previously untreated, high-risk non-Hodgkin's lymphoma (NHL). (duke.edu)
  • Fifty-five patients with refractory NHL and 13 with untreated, high-risk NHL were administered one cycle of daily cyclophosphamide 1.5 g/m2 intravenously on days 1-4 and etoposide 300 mg/m2 intravenously every 12 hours on days 1-3. (duke.edu)
  • In responders, the 2-year event-free survival was 27% in the refractory group and 56% in high-risk group. (duke.edu)
  • The information from different databases allowed them to estimate the incidence of Q fever and mature B-cell NHL by postal code and model the adjusted relative risk of mature B-cell NHL after Q fever infection. (medpagetoday.com)
  • In the last 25 years, we have seen a 40 percent increase in the incidence of non-Hodgkin lymphoma in both men and women, with the most dramatic increases occurring in the 1980s and early 1990s," said study leader Associate Professor Claire Vajdic, from the University of New South Wales Prince of Wales Clinical School. (edu.au)
  • increased incidence of lymphoma unequivocal evidence. (who.int)
  • Data on HIV infection and lymphoma characteristics, treatment and outcome were recorded. (uni-koeln.de)
  • For some indolent lymphomas, no treatment may be needed for some time. (epnet.com)
  • Your child's treatment team may order different tests based on what type of lymphoma is found. (uhhospitals.org)
  • Treatment choices also depend on the specific type of lymphoma. (uhhospitals.org)
  • This may not seem a very big difference, but it is important because the treatment for Hodgkin's and non-Hodgkin's lymphomas can be very different. (digitalnaturopath.com)
  • Knowing the grade and stage of a lymphoma helps the doctors to know how the lymphoma is likely to develop, how it may affect you and which treatment is most appropriate. (digitalnaturopath.com)
  • Similar complication rates were noted in the previously untreated, high-risk group, but there was no treatment-related mortality. (duke.edu)
  • After treatment, low-grade lymphomas usually get smaller or even disappear altogether. (cancer.ie)
  • Some types of low-grade lymphoma can be completely controlled with treatment. (cancer.ie)
  • Information for low-grade non-Hodgkin lymphoma patients, including tests, staging, treatment and side-effects, and how to cope. (cancer.ie)
  • Treatment depends on whether the lymphoma is slow- or fast-growing and if it is in one area or many areas. (wikipedia.org)
  • Which medications in the drug class Antineoplastic Agents, mTOR Kinase Inhibitors are used in the treatment of Non-Hodgkin Lymphoma (NHL)? (medscape.com)
  • Adult Non-Hodgkin Lymphoma Treatment (PDQ®): Health Professional Version. (medscape.com)
  • Each type of treatment for Hodgkin lymphoma (HL) has side effects that could last for months or longer. (cancer.org)
  • Knowing the stage and grade of the lymphoma helps your doctor plan the right treatment for you. (macmillan.org.uk)
  • The study investigated whether women who had responded successfully to treatment and subsequently became pregnant ran a higher risk of relapse than women who did not become pregnant. (ki.se)
  • So as you described, this patient has stage 4 Hodgkin lymphoma, and this is the kind of patient who, when the ECHELON-1 data first came out, you know, it really seemed, based on subset analyses, that this was the kind of patient who might benefit from the treatment most. (reachmd.com)
  • I completely agree that this is the exact patient that I am comfortable using brentuximab plus AVD and who I believe is probably getting more benefit out of the treatment than a patient who may be lower risk. (reachmd.com)
  • A number of biologic agents have been approved or are being studied for the treatment of high-risk melanoma. (limamemorial.org)
  • This is a randomized, double-blind, placebo-controlled, multicenter phase 3 trial to evaluate the efficacy and safety of brentuximab vedotin (SGN-35) and best supportive care (BSC) compared to placebo and BSC in treatment of residual Hodgkin lymphoma (HL) following autologous stem cell transplant (ASCT). (stanford.edu)
  • Typically treatment involves a wide variety of chemotherapeutic agents given in specific doses and combinations for the specific lymphoma. (rxwiki.com)
  • Radiation is frequently used as well, and is usually the primary treatment for non-Hodgkin lymphoma. (rxwiki.com)
  • The risk was significant for cases of non-Hodgkin lymphoma but not chronic lymphocytic leukaemia. (who.int)
  • Outcome of HIV-infected patients with AIDS-related lymphomas has improved during recent years. (uni-koeln.de)
  • This prospective observational multicenter study includes HIV-infected patients with biopsy-or cytology-proven malignant lymphomas since 2005. (uni-koeln.de)
  • According to NCCN guidelines, cardiac screening is recommended in this high-risk group of patients. (medscape.com)
  • The better tolerance, high response rate, and encouraging 2-year survival of this regimen in combination with further dose-dense consolidation in patients with high-risk NHL are encouraging. (duke.edu)
  • Martí-Carvajal AJ, Cardona AF, Lawrence A. Interventions for previously untreated patients with AIDS-associated non-Hodgkin's lymphoma. (medscape.com)
  • If you are a healthcare professional, use our guide to find the right information and support for your patients affected by lymphoma. (macmillan.org.uk)
  • Current clinical trials for children with HL aim to further segregate patients into risk strata such that those who are highly curable can receive less toxic therapy, whereas high-risk patients can receive augmented therapy. (ices.on.ca)
  • TUESDAY, April 28, 2015 (HealthDay News) - Physicians and patients should be aware of the persistently increased risk of cardiovascular diseases throughout life after Hodgkin's lymphoma, according to a report published online April 27 in JAMA Internal Medicine . (ehealth-news.com)
  • Flora van Leeuwen, Ph.D., of the Netherlands Cancer Institute in Amsterdam, and colleagues examined the medical records of 2,524 Dutch patients who were treated for Hodgkin's lymphoma between 1965 and 1995, and were diagnosed before the age of 51. (ehealth-news.com)
  • The results of our study may direct guidelines for follow-up of patients with Hodgkin's lymphoma," the authors write. (ehealth-news.com)
  • Unlike other types of lymphoma, a high proportion of patients develop Hodgkin lymphoma in their 20s and 30s. (ki.se)
  • These benefits mean pixantrone can be administered to patients over the long term, without unacceptable cardiotoxicity risks. (genengnews.com)
  • The ongoing challenge is how to further improve outcomes by identifying both high-risk patients who may benefit from more intensive frontline therapy to reduce the risk of relapse as well as lower-risk patients who may do just as well with less intensive therapy. (ashpublications.org)
  • 1 , 2 When stratified by the International Prognostic Score (IPS), the 5-year PFS and OS rates were 77% and 91% for low-risk patients (IPS of 0-2) and 67% and 84% for high-risk patients (IPS ≥ 3), respectively. (ashpublications.org)
  • We think as a population of patients where the regimen might be most useful, the extra toxicities that we take on in terms of peripheral neuropathy, the need to use growth factor to abrogate the risk of neutropenia and febrile neutropenia and sepsis, really, I think are worth taking on in a high-risk patient like this where we're really trying to give them the best shot at a cure. (reachmd.com)
  • Breast cancer patients are risking their lives by failing to take the tamoxifen they are prescribed, according to a new study published in the British Journal of Cancer. (canceractive.com)
  • While each type of lymphoma has its own prognosis, it is generally a very treatable illness, with over 80% of patients diagnosed early being alive after five years. (rxwiki.com)
  • Family history of venous thromboembolism and risk of hospitalized thromboembolism in cancer patients: A nationwide family study. (cdc.gov)
  • Familial Risk in Patients With Carcinoma of Unknown Primary. (cdc.gov)
  • This risk is decreasing as drugs are developed to treat AIDS and HIV infection. (cancer.ca)
  • Having a weak immune system (from an inherited condition, HIV infection, or certain drugs) increases the risk of developing non-Hodgkin's lymphoma. (daviddarling.info)
  • People who have HIV infection are at much greater risk of some types of non-Hodgkin's lymphoma. (daviddarling.info)
  • Epstein-Barr virus (EBV): Infection with EBV has been linked to an increased risk of lymphoma. (daviddarling.info)
  • In Africa, EBV infection is linked to Burkitt's lymphoma. (daviddarling.info)
  • Human T-cell leukemia/lymphoma virus (HTLV-1): Infection with HTLV-1 increases a person's risk of lymphoma and leukemia. (daviddarling.info)
  • It has also been proposed that hepatitis B virus (HBV) may be an etiologic agent of Non-Hodgkin's Lymphoma (NHL) [15] - [17] , but relatively few studies have investigated the association between HBV infection and B-NHL. (scirp.org)
  • In conclusion, complete remission and relapse rates observed in our study are similar to those reported in HIV-negative non-Hodgkin lymphomas. (uni-koeln.de)
  • Pregnancy does not increase the risk of relapse among women successfully treated for Hodgkin lymphoma. (ki.se)
  • The results of this study therefore provide no evidence that pregnancy increases the risk of relapse in women who have been successfully treated for Hodgkin lymphoma. (ki.se)
  • However, given the results of this study, the risk of pregnancy-associated relapse does not need to be considered. (ki.se)
  • There are two types of lymphoma, they include Hodgkin's and non-Hodgkin's lymphoma. (checkbiotech.org)
  • People with HIV (human immunodeficiency virus) or AIDS (acquired immunodeficiency syndrome) have a greater risk of developing some types of NHL. (cancer.ca)
  • They also have a higher risk of developing certain types of cancer. (cancer.ca)
  • Certain infections: Having certain types of infections increases the risk of developing lymphoma. (daviddarling.info)
  • Non-Hodgkin lymphoma is a name that applies to many types of lymphomas. (epnet.com)
  • There are about 20 different types of non-Hodgkin's lymphoma. (digitalnaturopath.com)
  • As medical science has developed over the years, it has been realized that there are over 20 different types of non-Hodgkin's lymphoma , each with its own characteristics and behavior. (digitalnaturopath.com)
  • What are the types of non-Hodgkin lymphoma? (cancer.ie)
  • Within the four groups for NHL are over 60 specific types of lymphoma. (wikipedia.org)
  • People who've had HL have a higher risk for many types of cancer. (cancer.org)
  • You are at increased risk if you have a weakened immune system or have certain types of infections. (medlineplus.gov)
  • The objective of this study was to investigate the association between persistent use of statins and the risk of overall and site-specific cancer in adults, to assess dose-response relationship, and to examine the effects of varying types of statins. (cdc.gov)
  • Conclusions: These findings are compatible with previous reports, adding to the evidence that firefighters are at increased risk of a number of types of cancer. (cdc.gov)
  • NSHL is a type of lymphoma. (medicalnewstoday.com)
  • Generally speaking, this type of NHL grows more slowly than other lymphomas and is less likely to spread to the bone marrow or brain. (acco.org)
  • Background: Previous epidemiological studies of the relation between alcohol consumption and risk of non-Hodgkin lymphoma (NHL) have been inconsistent, probably because of small sample sizes of individual studies that result from stratification by NHL subtype and type of alcoholic beverage. (elsevierpure.com)
  • Non-Hodgkin lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. (medlineplus.gov)
  • The following viral and bacterial infections can increase the risk of developing NHL. (cancer.ca)
  • Inherited gene changes and some viral infections may increase a child's risk of having NHL. (uhhospitals.org)
  • Association of Germline BRCA2 Mutations With the Risk of Pediatric or Adolescent Non-Hodgkin Lymphoma. (cdc.gov)
  • People who have a weakened immune system have a higher risk of developing NHL. (cancer.ca)
  • No matter when your immune system is damaged, it doesn't change your risk for developing NHL. (cancer.ca)
  • Weakened immune system: The risk of developing lymphoma may be increased by having a weakened immune system (such as from an inherited condition or certain drugs used after an organ transplant). (rxwiki.com)
  • Lymphoma is a cancer of a part of the immune system called the lymph system. (medlineplus.gov)
  • Methods: Standardized morbidity odds ratio (SMORs) were used to evaluate the cancer risk in white, male firefighters compared to police and all other occupations in the Massachusetts Cancer Registry from 1986 to 2003. (cdc.gov)
  • The National Cancer Institute's Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J. (medscape.com)
  • Computed tomography-based tumor volume in non-Hodgkin lymphoma: clinical correlation and comparison with magnetic resonance imaging. (medscape.com)
  • Additionally, many new treatments called monoclonal antibodies have been successfully used ( rituximab ( Rituxan ) for B-cell lymphomas, ofatumumab (Arzerra) for NHL, Ocrelizumab is in clinical trials). (rxwiki.com)
  • The Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J.{Ref 1} In 1994, the Revised European-American Lymphoma (REAL) classification attempted to apply immunophenotypic and genetic features in identifying distinct clinicopathologic NHL entities. (medscape.com)
  • Zhang QY, Foucar K. Bone marrow involvement by Hodgkin and non-Hodgkin lymphomas. (medscape.com)
  • So you have a 27-year-old female patient who has an International Prognostic Score [IPS] of 5 and is diagnosed with stage 4 Hodgkin lymphoma associated with bone and liver involvement. (reachmd.com)
  • People who take immunosuppressant drugs after a solid organ transplant (such as a kidney, heart or liver transplant) have a higher risk for NHL. (cancer.ca)
  • But their risk is lower than for people who take immunosuppressant drugs after an organ transplant. (cancer.ca)
  • Time trends in risk and risk determinants of non-hodgkin lymphoma in solid organ transplant recipients. (medscape.com)