Hemic and Lymphatic Diseases
Endothelium, Lymphatic
Ki-1 (CD30)-positive anaplastic large cell lymphoma, sarcomatoid variant accompanied by spontaneously regressing lymphadenopathy. (1/851)
Although it has been reported that primary Ki-1 (CD30)-positive anaplastic large cell lymphoma (ALCL) of the skin may undergo spontaneous regression, it is rare for ALCL without cutaneous involvement to have spontaneously regressing lymphadenopathy. We report a case of sarcomatoid variant of ALCL accompanied by spontaneously regressing lymphadenopathy. The patient had gastric and pulmonary involvement of ALCL in addition to systemic lymphadenopathy, but with no cutaneous involvement. The lymphadenopathy spontaneously improved gradually during a period of one month without any treatment. At the same time, multiple small nodules in both lung fields decreased on chest computed tomography and multiple elevated gastric tumors with dimples were endoscopically recognized to have improved. He has since been treated with combination chemotherapy because of recurrence of the lymphadenopathy. (+info)Angiogenesis extent and macrophage density increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas. (2/851)
Node biopsies of 30 benign lymphadenopathies and 71 B-cell non-Hodgkin's lymphomas (B-NHLs) were investigated for microvessel and macrophage counts using immunohistochemistry and morphometric analysis. Both counts were significantly higher in B-NHL. Moreover, when these were grouped into low-grade and high-grade lymphomas, according to the Kiel classification and Working Formulation (WF), statistically significant higher counts were found in the high-grade tumours. Immunohistochemistry and electron microscopy revealed a close spatial association between microvessels and macrophages. Overall, the results suggest that, in analogy to what has already been shown in solid tumours, angiogenesis occurring in B-NHLs increases with tumour progression, and that macrophages promote the induction of angiogenesis via the release of their angiogenic factors. (+info)Adrenergic innervation in reactive human lymph nodes. (3/851)
Several experimental models have demonstrated that the central nervous system is functionally linked to the immune system by means of the autonomic nervous system. Samples of 36 lymph nodes of patients whose ages ranged from 16 to 69 y were studied. In order to demonstrate the existence and distribution of sympathetic nerve fibres, a polyclonal antibody antityrosine hydroxylase (TH), with the streptavidin-biotin system of detection, was used. TH-positive nerve fibres appeared in all reactive patterns of the lymph nodes studied. Thin nerve fascicles ramified at the hilar region and also in the connective tissue septae. Adventitial adrenergic nerve fibres were found following afferent, and to a lesser extent, efferent blood vessels. Another source of incoming nerve fibres was found at capsular level, accompanying blood vessels. On the arterial side, the innervation ceased before reaching the follicular arterioles. Our demonstration of innervation in postcapillary venules could support a regulatory role of adrenergic neurotransmitters in lymphocyte traffic. Occasional nerve fibres were also seen in T areas among parenchymatous cells. These findings confirm the existence of sympathetic innervation in human lymph nodes, and provide indirect evidence that the psychoneuroimmune axis could also exist in humans. (+info)The prevalence and CT appearance of the levator claviculae muscle: a normal variant not to be mistaken for an abnormality. (4/851)
BACKGROUND AND PURPOSE: The levator claviculae muscle is an infrequently recognized variant in humans, occurring in 2% to 3% of the population, and has rarely been reported in the radiologic or anatomic literature. The importance of this muscle to radiologists is in distinguishing it from an abnormality; most commonly, cervical adenopathy. After discovering this muscle on the CT scans of two patients during routine clinical examinations, we conducted a study to determine the prevalence and appearance of the muscle on CT studies. METHODS: We evaluated 300 CT scans that adequately depicted the expected location of the muscle. The most superior level in which the muscle could be identified and the apparent location of insertion on the clavicle were recorded for all subjects in whom the muscle was detected. RESULTS: Seven levator claviculae muscles were identified in six subjects (2%). It was bilateral in one, on the left in four, and on the right in one. It was identified up to the level of the transverse process of C3 in all cases. The insertion was the middle third of the clavicle for two muscles and the lateral third of the clavicle for the remaining five muscles. CONCLUSION: Because the levator claviculae muscle will most likely be encountered during a radiologist's career, it is important to recognize this muscle as a variant and not as an abnormality. (+info)Primary Sjogren's syndrome in the North East of England: a long-term follow-up study. (5/851)
OBJECTIVE: Although primary Sjogren's syndrome is often a benign condition, characterized by lymphocytic infiltration of salivary and lacrimal glands, some patients develop systemic features. We have previously found that anti-Ro antibodies identified patients with more systemic disease, with increased incidence of parotid swelling, lymphadenopathy and lymphoma. METHODS: We have followed up a cohort of 100 patients over 10 yr, to establish whether the phenotypic expression of disease changed, and whether the different autoantibody patterns expressed at presentation could be used to predict outcome. RESULTS: While seronegative patients (ANA, RF, Ro and La negative) remained polysymptomatic, they did not develop systemic complications or serological changes. Thirty-nine per cent of ANA- or RF-positive patients who were negative for Ro and La were given revised diagnoses over the follow-up period, including rheumatoid arthritis, systemic lupus erythematosus, mixed connective tissue disease and scleroderma. Parotid swelling and lymphadenopathy were more common in Ro/La-positive patients, where the relative risk of developing non-Hodgkin's lymphoma was 49.7. CONCLUSION: Both HLA B8 and DR3 were present in 79% of Ro/La-positive patients, but were found together in only 4% of seronegative patients, supporting the view that these clinical subgroups of primary Sjogren's syndrome are both serologically and immunogenetically distinct. Patients who are initially autoantibody (including Ro and La) negative do not evolve into 'systemic' Sjogren's syndrome or other connective tissue diseases. (+info)A central role for alpha beta T cells in the pathogenesis of murine lupus. (6/851)
We have previously shown that female transgenic mice expressing IFN-gamma in the epidermis, under the control of the involucrin promoter, develop inflammatory skin disease and a form of murine lupus. To investigate the pathogenesis of this syndrome, we generated female IFN-gamma transgenic mice congenitally deficient in either alpha beta or gamma delta T cells. TCR delta-/- transgenics continued to produce antinuclear autoantibodies and to develop severe kidney lesions. In contrast, TCR beta-/- IFN-gamma transgenic mice failed to produce antinucleosome, anti-dsDNA, or antihistone autoantibodies, and kidney disease was abolished. Both alpha beta- and gamma delta-deficient transgenics continued to develop IFN-gamma-associated skin disease, lymphadenopathy, and splenomegaly. The data show that the autoantibody-mediated pathology of murine lupus in IFN-gamma transgenic mice is completely alpha beta T cell dependent and that gamma delta T cells cannot drive autoantibody production. These results imply that production of antinuclear autoantibodies in IFN-gamma transgenic animals is Ag driven, and we identified clusters of apoptotic cells in the epidermis of the mice as a possible source of self Ags. Our findings emphasize the relevance of this murine lupus model to the human disease. (+info)Cladribine activity in adult langerhans-cell histiocytosis. (7/851)
Langerhans-cell histiocytosis (LCH) results from the accumulation of tissue histiocytes derived from the same progenitor cells as monocytes. Because cladribine is potently toxic to monocytes, we conducted a phase II trial of cladribine. Cladribine was administered to 13 LCH patients at 0.14 mg/kg per day by 2-hour intravenous infusion for 5 consecutive days, every 4 weeks for a maximum of six courses. Median age was 42 years (range, 19 to 72) and median pretreatment disease duration was 99 months (range, 6 to 252). One patient was untreated, one had received prior prednisone only, one prior radiation only, six prior radiation and chemotherapy, and four prior surgery, radiation, and chemotherapy. Seven patients had cutaneous involvement, six multifocal osseous, six pulmonary, two each with soft tissue and nodal involvement, and four had diabetes insipidus. Of 13 patients, 12 were evaluable for response and all for toxicity. After a median of three courses (range, 1 to 6), seven (58%) patients achieved complete responses (two pathologic and five clinical) and two (17%) patients achieved partial responses; overall response rate, 75%. Median response follow-up duration was 33 months (range, 1 to 65). Seven patients experienced grade 3 to 4 neutropenia. Only one patient had a documented infection, dermatomal herpes zoster. At a median follow-up of 42 months (range, 5 to 76), 12 patients remain alive and one patient has died. Thus, cladribine has major activity in adult LCH and warrants further investigation in both pediatric and adult LCH as a single agent and in combination with other drugs. (+info)Lymphatic and haematopoietic cancer mortality in a population attending school adjacent to styrene-butadiene facilities, 1963-1993. (8/851)
STUDY OBJECTIVE: To evaluate the risk of mortality from lymphatic and haematopoietic cancers and other causes among students. DESIGN: The study used school records, yearbooks, and Texas Department of Health records for the school years 1963-64 to 1992-93 to construct a cohort of 15,403 students. Three mortality databases were searched to identify deaths, and mortality rates in the cohort were compared with mortality rates from the United States and Texas. Computed standardised mortality ratios and 95% confidence intervals were used. SETTING: Eastern Texas high school adjacent to facilities that have been producing synthetic styrene-butadiene since 1943. MAIN RESULTS: 338 deaths were identified. The all causes standardised mortality ratio was 0.84 (95% confidence intervals 0.74, 0.95) for men and 0.89 (0.73, 1.09) for women. The standardised mortality ratio for all lymphatic and haematopoietic cancers was 1.64 (95% confidence intervals 0.85, 2.87) for men and 0.47 (0.06, 1.70) for women. The slight male excess in lymphatic and haematopoietic cancers was stronger among men who attended school for two years or less. CONCLUSIONS: The overall mortality from lymphatic and haematopoietic cancer among the students was little different from that of the United States as a whole. A moderate excess for men, predominantly among the shorter-term students, was offset by a deficit among women. These variations are compatible with random fluctuations; the overall pattern is not indicative of an effect of environmental exposure sustained while attending the high school. (+info)Hemic diseases typically refer to conditions that affect the blood, bone marrow, or lymphatic system. Here are some examples:
1. Hematologic disorders: These are diseases related to the blood and include anemia (deficiency of red blood cells), leukemia (cancer of white blood cells), hemophilia (a genetic disorder that affects the blood's ability to clot), and thalassemia (a genetic disorder affecting red blood cell production).
2. Bone marrow disorders: These are conditions that affect the bone marrow, which is the spongy tissue inside bones where blood cells are produced. Examples include aplastic anemia (where the bone marrow doesn't produce enough new cells), myelodysplastic syndromes (conditions where the bone marrow produces abnormal cells), and leukemia.
3. Lymphatic disorders: These are conditions that affect the lymphatic system, which is a network of tissues and organs that help rid the body of waste and toxins. Examples include lymphoma (cancer of the lymphatic system), Hodgkin's disease, and non-Hodgkin's lymphoma.
It's important to note that this is not an exhaustive list, and there are many other hemic and lymphatic diseases. If you have concerns about any symptoms or conditions, it's best to consult with a healthcare professional for accurate information and treatment options.
Lymphatic diseases refer to a group of conditions that affect the lymphatic system, which is an important part of the immune and circulatory systems. The lymphatic system consists of a network of vessels, organs, and tissues that help to transport lymph fluid throughout the body, fight infection, and remove waste products.
Lymphatic diseases can be caused by various factors, including genetics, infections, cancer, and autoimmune disorders. Some common types of lymphatic diseases include:
1. Lymphedema: A condition that causes swelling in the arms or legs due to a blockage or damage in the lymphatic vessels.
2. Lymphoma: A type of cancer that affects the lymphatic system, including Hodgkin's and non-Hodgkin's lymphoma.
3. Infections: Certain bacterial and viral infections can affect the lymphatic system, such as tuberculosis, cat-scratch disease, and HIV/AIDS.
4. Autoimmune disorders: Conditions such as rheumatoid arthritis, lupus, and scleroderma can cause inflammation and damage to the lymphatic system.
5. Congenital abnormalities: Some people are born with abnormalities in their lymphatic system, such as malformations or missing lymph nodes.
Symptoms of lymphatic diseases may vary depending on the specific condition and its severity. Treatment options may include medication, physical therapy, surgery, or radiation therapy. It is important to seek medical attention if you experience symptoms of a lymphatic disease, as early diagnosis and treatment can improve outcomes.
Lymphatic vessels are thin-walled, valved structures that collect and transport lymph, a fluid derived from the interstitial fluid surrounding the cells, throughout the lymphatic system. They play a crucial role in immune function and maintaining fluid balance in the body. The primary function of lymphatic vessels is to return excess interstitial fluid, proteins, waste products, and immune cells to the bloodstream via the subclavian veins near the heart.
There are two types of lymphatic vessels:
1. Lymphatic capillaries: These are the smallest lymphatic vessels, found in most body tissues except for the central nervous system (CNS). They have blind ends and are highly permeable to allow the entry of interstitial fluid, proteins, and other large molecules.
2. Larger lymphatic vessels: These include precollecting vessels, collecting vessels, and lymphatic trunks. Precollecting vessels have valves that prevent backflow of lymph and merge to form larger collecting vessels. Collecting vessels contain smooth muscle in their walls, which helps to propel the lymph forward. They also have valves at regular intervals to ensure unidirectional flow towards the heart. Lymphatic trunks are large vessels that collect lymph from various regions of the body and eventually drain into the two main lymphatic ducts: the thoracic duct and the right lymphatic duct.
Overall, lymphatic vessels play a vital role in maintaining fluid balance, immune surveillance, and waste removal in the human body.
The lymphatic system is a complex network of organs, tissues, vessels, and cells that work together to defend the body against infectious diseases and also play a crucial role in the immune system. It is made up of:
1. Lymphoid Organs: These include the spleen, thymus, lymph nodes, tonsils, adenoids, and Peyer's patches (in the intestines). They produce and mature immune cells.
2. Lymphatic Vessels: These are thin tubes that carry clear fluid called lymph towards the heart.
3. Lymph: This is a clear-to-white fluid that contains white blood cells, mainly lymphocytes, which help fight infections.
4. Other tissues and cells: These include bone marrow where immune cells are produced, and lymphocytes (T cells and B cells) which are types of white blood cells that help protect the body from infection and disease.
The primary function of the lymphatic system is to transport lymph throughout the body, collecting waste products, bacteria, viruses, and other foreign substances from the tissues, and filtering them out through the lymph nodes. The lymphatic system also helps in the absorption of fats and fat-soluble vitamins from food in the digestive tract.
The endothelium is a thin layer of cells that lines the interior surface of blood vessels and lymphatic vessels. The lymphatic endothelium, specifically, is the type of endothelial cell that forms the walls of lymphatic vessels. These vessels are an important part of the immune system and play a crucial role in transporting fluid, waste products, and immune cells throughout the body.
The lymphatic endothelium helps to regulate the movement of fluids and cells between the tissues and the bloodstream. It also contains specialized structures called valves that help to ensure the unidirectional flow of lymph fluid towards the heart. Dysfunction of the lymphatic endothelium has been implicated in a variety of diseases, including lymphedema, inflammation, and cancer metastasis.
Lymphangiogenesis is the formation of new lymphatic vessels from pre-existing ones. It is a complex biological process that involves the growth, differentiation, and remodeling of lymphatic endothelial cells, which line the interior surface of lymphatic vessels. Lymphangiogenesis plays crucial roles in various physiological processes, including tissue drainage, immune surveillance, and lipid absorption. However, it can also contribute to pathological conditions such as cancer metastasis, inflammation, and fibrosis when it is dysregulated.
The process of lymphangiogenesis is regulated by a variety of growth factors, receptors, and signaling molecules, including vascular endothelial growth factor (VEGF)-C, VEGF-D, and their receptor VEGFR-3, as well as other factors such as angiopoietins, integrins, and matrix metalloproteinases. Understanding the mechanisms of lymphangiogenesis has important implications for developing novel therapies for a range of diseases associated with abnormal lymphatic vessel growth and function.
Lymphatic disease
Lymphatic filariasis in India
Global Programme to Eliminate Lymphatic Filariasis
Eradication of lymphatic filariasis
Lymphatic malformation 6 syndrome
Lymphatic vessel
Right lymphatic duct
Lymphatic system
Wuchereria bancrofti
List of infectious diseases
Bone marrow
Brugia timori
Vascular malformation
Lymphohemangioma
Bancroft's sign
Lymphedema
Thalidomide
Neglected tropical diseases in India
Human body
Filariasis
Chronic progressive lymphedema
Health in Bangladesh
Meningeal lymphatic vessels
Helminthiasis
Milroy's disease
Kigali Declaration on Neglected Tropical Diseases
Gorham's disease
Interstitium
Tropical pulmonary eosinophilia
Loa loa filariasis
Lymphatic disease - Wikipedia
Lymphatic Diseases | Lymph Nodes | Swollen Glands | MedlinePlus
Review of Malpractice Litigation in the Diagnosis and Treatment of Venous & Lymphatic Disease
Template:Lymphatic disease - wikidoc
Endpoints for Lymphatic Filariasis Programs - Volume 13, Number 4-April 2007 - Emerging Infectious Diseases journal - CDC
NIH VideoCast - Yet to Be Charted: Lymphatic System in Health and Disease (Day 2)
The Lymphatics in Kidney Disease (Discoveries & Impact August 2023) | Internal Medicine
Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson's disease | Lund University Publications
RFA-DK-18-021: Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed)
What kind of disease is lymphatic filariasis - The Medical Questions
WHO EMRO | Twelfth meeting of the Regional Programme Review Group (RPRG) on lymphatic filariasis elimination and other...
WHO EMRO | Training in monitoring and epidemiological assessment of mass drug administration for eliminating lymphatic...
Cystic Hygroma (Macrocystic Lymphatic Malformation) Imaging and Diagnosis: Practice Essentials, Magnetic Resonance Imaging,...
The Role of Hyperactive KRAS Signaling in Complex Lymphatic Anomalies : 2023 CLA Conference : Videos : Researchers & Clinicians...
Elimination of lymphatic filariasis in South East Asia | The BMJ
Modulating Vascular Lymphatic Growth in Disease: Current and Potential Pharmacological Approaches for Prevention and Treatment
CDC - Lymphatic Filariasis
Significant improvement in quality of life following surgery for hydrocoele caused by lymphatic filariasis in Malawi: A...
Cardiovascular, Lymphatic and Metabolic Disease
EISAI RECEIVES PREQUALIFICATION FROM WORLD HEALTH ORGANIZATION FOR LYMPHATIC FILARIASIS MEDICINE DIETHYLCARBAMAZINE | News...
Structure and Function of the Lymphatic System in Dogs
Cardiovascular & Lymphatic Systems | Carolina Biological Supply
LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C | Nature...
Infectious Diseases Affecting the Cardiovascular and Lymphatic Systems
2020-2021 BCSC Basic and Clinical Science Course™
Clinical Experts Meeting on Lymphatic Filariasis | DNDi
Bancroftian and Brugian Lymphatic Filariasis - Infectious Diseases - MSD Manual Professional Edition
Targeted Lymphatic and Microvessel Treatments in metabolic-DISease HFpEF - Science Teams
Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era? ...
Developing a community-led SMS reporting tool for the rapid assessment of lymphatic filariasis morbidity burden: case studies...
Lymph nodes11
- The lymphatic system occurs throughout the body and is made up of small glands called lymph nodes, which are connected to each other by a series of vessels called lymphatics. (petplace.com)
- The lymph nodes are connected to each other by a series of vessels called lymphatics, which carry lymph from place to place. (petplace.com)
- The lymphatic system is composed of a network of lymph vessels referred to as lymphatics, as well as certain organs and tissues, including the lymph nodes, bone marrow, spleen, thymus and GALT. (petplace.com)
- The lymph moves through the lymphatic vessels toward the lymph nodes. (petplace.com)
- The lymph nodes lie at varying points along the course of the lymphatic chain and can form clusters in some areas of the body. (petplace.com)
- Lymph nodes are usually small, bean-shaped structures that filter harmful substances and waste from the lymphatic fluid. (remedypost.com)
- Conditions that cause swollen lymph nodes, such as autoimmune diseases and hormonal imbalances, may indirectly contribute to acne. (remedypost.com)
- Lymphatic drainage facials and massages stimulate the lymphatic system and promote waste removal, potentially reducing the risk of swollen lymph nodes. (remedypost.com)
- Kikuchi Fujimoto disease (KFD) is a rare condition that affects a person's lymph nodes. (medicalnewstoday.com)
- KFD is a very rare disease that can cause a person to have swollen lymph nodes. (medicalnewstoday.com)
- The adult filarial worms primarily reside in the lymphatic vessels and lymph nodes. (who.int)
Eliminating lymphatic filariasis1
- The World Health Organization (WHO) and other global health bodies have initiated programs aimed at eliminating lymphatic filariasis as a public health problem. (who.int)
Lymphedema13
- Examples include Castleman's disease and lymphedema. (wikipedia.org)
- Globally, more than 1 billion persons are at risk for lymphatic filariasis (LF), a mosquito-transmitted parasitic infection that causes lymphedema and hydrocele. (cdc.gov)
- People with lymphedema, lipedema, and other lymphatic diseases will share their personal experiences. (nih.gov)
- Featured topics include lymphedema and the role of lymphatics in obesity. (nih.gov)
- However, morphological or functional changes in lymphatic vessels can contribute to disorders such as lymphedema, tumor metastasis, inflammation and other pathological conditions (Oliver et al. (uma.es)
- and review articles that highlight and discuss the latest pharmacological approaches to treat lymphedema and mechanisms to target obesity and metabolic diseases through modulating lymphatic contraction. (uma.es)
- People with the disease can suffer from lymphedema and elephantiasis and in men, swelling of the scrotum, called hydrocele. (cdc.gov)
- In most patients, asymptomatic lymphatic dilation occurs, but chronic inflammatory responses to adult worms and secondary bacterial infections may result in chronic lymphedema of the affected body area. (msdmanuals.com)
- Chronic pitting lymphedema of a lower extremity can progress to elephantiasis (chronic lymphatic obstruction). (msdmanuals.com)
- Although lymphedema may not be a classic symptom of tick-borne diseases, Lyme patients can potentially develop it. (rawlsmd.com)
- This lecture explains the disease of veins namely Varicose veins, Thrombophlebitis and Phlebothrombosis, Syndrome of Superior Vena Cava and Syndrome of Inferior Vena Cava, diseases of lymphatics i.e Lymphangitis and Lymphedema. (howmed.net)
- LE&RN, in partnership with Stanford University, has established the International Lymphatic Disease and Lymphedema Patient Registry and Biorepository to collect information about individuals diagnosed with a lymphatic disease. (lymphnotes.com)
- Most notably, it can cause lymphedema (swelling) of limbs and genital disease, including hydrocele (swelling of the scrotum), chylocele, and swelling of the penis. (who.int)
Components of the lymphatic system1
- Lymphatic disease is a class of disorders which directly affect the components of the lymphatic system. (wikipedia.org)
Function of the Lymphatic System1
- The function of the lymphatic system is that of a waste management center for the body. (rawlsmd.com)
Functions of the lymphatic system3
- A new article in Kidney360 provides a comprehensive overview of the functions of the lymphatic system in several kidney disease states. (yale.edu)
- What Are the Functions of the Lymphatic System in Dogs? (petplace.com)
- Similar to the action of the cardiovascular system , many of the functions of the lymphatic system happen without much awareness on your part. (rawlsmd.com)
Onchocerciasis2
- As a result, the scope of the current WHO Regional Office-RPRG meeting is being broadened to involve discussions on three major neglected tropical diseeases (lymphatic filariasis, schistosomiasis and onchocerciasis) amenable to preventive chemotherapy. (who.int)
- Lymphatic filariasis and schistosomiasis are present in Egypt, Sudan and Yemen, whereas onchocerciasis is transmitted in Sudan and Yemen only. (who.int)
Filariasis elimination1
- Participants of the Twelfth meeting of the Regional Programme Review Group (RPRG) on lymphatic filariasis elimination and other preventive chemotherapy programmes The twelfth meeting of the Regional Programme Review Group (RPRG) on lymphatic filariasis elimination and other preventive chemotherapy programmes took place in Sharm El Sheikh, Egypt, from 21 to 23 October 2013. (who.int)
Elephantiasis2
- One of them is Lymphatic Filariasis, also known as Elephantiasis. (haitiinnovation.org)
- Lymphatic filariasis (LF), commonly known as elephantiasis, is a painful and profoundly disfiguring disease. (who.int)
Endothelial cell3
- Dive into the intriguing discoveries made by researchers, including the impact of mutant KRAS on lymphatic vessels in newborn animals versus young adults, and the expansion of specific lymphatic endothelial cell populations. (lgdalliance.org)
- Explore the next steps in this research journey, including validating single-cell RNA sequencing data, characterizing newly identified lymphatic endothelial cell populations, and studying the potential molecular mechanisms behind lymphatic valve loss. (lgdalliance.org)
- Thereafter, a distinct subpopulation of endothelial cells lining the cardinal vein starts differentiating by expressing the TF PROX1, the master regulator of lymphatic endothelial cell (LEC) identity, via the TFs SOX18 and COUPTFII. (nature.com)
Aspects of lymphatic vessel2
- The purpose of this FOA is to invite applications that investigate aspects of lymphatic vessel physiology, development and pathophysiology related to health and diseases of the digestive system. (nih.gov)
- The 2020 Gordon Research Conference on Lymphatics will bring together leading international scientists and clinicians working across all aspects of lymphatic vessel biology to discuss the latest advances in this exciting and dynamic field. (grc.org)
Organs8
- The lymphatic system is a network of tissues and organs. (medlineplus.gov)
- Studies to understand the factors that control local lymphatic vessel functional anatomy and physiology and development during health or disease in this system and its organs, and the mechanisms by which alterations of lymphatic vessel function affect organ function, are of interest. (nih.gov)
- However, studies with the major focus on immune mechanisms, role of lymphatics in cancer metastasis and study of lymphatic vessels in organs other than those from the digestive system will not be considered responsive. (nih.gov)
- Lymphatic vessels within different organs and in different physiological and pathological processes show a remarkable plasticity and heterogeneity, reflecting their functional specialization. (nih.gov)
- In addition, lymphatic endothelial cells of different organs have been recently shown to have alternative developmental origins, which may contribute to the development of the diverse lymphatic vessel and endothelial functions seen in the adult. (nih.gov)
- Other important organs in this system include the bone marrow, spleen, thymus and gut-associated lymphoid tissue (GALT), which is the lymphatic tissue associated with the gastrointestinal (GI) tract. (petplace.com)
- The lymphatic vessels and secondary lymphoid organs (SLOs) are arranged in a manner that optimizes interactions among antigens, APCs, and innate and adaptive effector cells. (jci.org)
- Shira Shafir] We know that people with compromised or suppressed immune systems are more likely to get severe disease because their immune systems are not able to control the infection and this allows the fungus to spread from the lungs to other organs. (cdc.gov)
Endothelium2
- Lee Y, Chakraborty S, Meininger CJ, Muthuchamy M. Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium . (tamu.edu)
- Chakraborty S, Zawieja DC, Davis MJ, Muthuchamy M. MicroRNA signature of inflamed lymphatic endothelium and role of miR-9 in lymphangiogenesis and inflammation [published correction appears in Am J Physiol Cell Physiol. (tamu.edu)
Causes lymphatic dysfunction2
Infection9
- The lymphatic system clears away infection and keeps your body fluids in balance. (medlineplus.gov)
- While infection is usually acquired during childhood, symptoms often gradually appear over several years, with the most serious manifestations of the disease occurring in adulthood. (eisai.com)
- Lymphatic filariasis is infection with any of 3 species of Filarioidea . (msdmanuals.com)
- We used mathematical modelling to estimate the impact of delaying or cancelling treatment rounds and explore possible mitigation strategies.MethodsWe used three established lymphatic filariasis transmission models to simulate infection trends in settings with annual treatment rounds and programme delays in 2020 of 6, 12, 18 or 24 months. (ox.ac.uk)
- Infection over long periods leads to damage of the lymphatic system, which can manifest as lymphoedema and hydrocele (scrotal swelling). (kit.nl)
- [ 1 ] Although the prevalence of MAI infection has increased following the epidemic of acquired immunodeficiency syndrome (AIDS), MAI infection remains a rare cause of skin disease. (medscape.com)
- In the United States, Mycobacterium avium-intracellulare (MAI, or MAC) infection is considered a nonreportable infectious disease. (medscape.com)
- This coincidence concords with the fact that DMAI infection often occurs in association with HIV disease. (medscape.com)
- A review of 8 cases of cutaneous MAI infection occurring secondary to disseminated disease found a median patient age of 22.2 years, with a range of 2-28 years. (medscape.com)
Dysfunction3
- Animal studies implicate meningeal lymphatic dysfunction in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease (PD). (lu.se)
- These results suggest that meningeal lymphatic drainage dysfunction aggravates α-syn pathology and contributes to the progression of PD. (lu.se)
- 2020). Therefore, there is an urgent need to further understand the mechanisms driving lymphatic dysfunction in these conditions and to develop novel lymph-targeted therapies. (uma.es)
Pathology2
- In mice injected with α-synuclein (α-syn) preformed fibrils, we showed that the emergence of α-syn pathology was followed by delayed meningeal lymphatic drainage, loss of tight junctions among meningeal lymphatic endothelial cells and increased inflammation of the meninges. (lu.se)
- In optimal settings, MRI can provide exquisite anatomic detail, and it can be especially helpful in identifying additional pathology, as well as in determining the extent of the disease. (medscape.com)
Roles of lymphatic1
- Many of these functions include key roles of lymphatic vessels, yet the roles of lymphatics, the character of the vessels in the intestinal environment and key regulators of lymphatic function in intestinal health and disease remain understudied. (nih.gov)
Cardiovascular4
- This chapter discusses the impact of infectious diseases on the cardiovascular and lymphatic systems, including the structure and function of the cardiovascular system and its defense mechanisms. (presentica.com)
- Cardiovascular disease causes one-third of deaths worldwide and represents an urgent threat to global health. (nature.com)
- The scientific, clinical, pharmacological and public health communities have coordinated efforts to prevent, diagnose, treat and cure cardiovascular disease. (nature.com)
- Rather than supporting specific research projects, the Merit Awards support scientists - those who propose novel approaches to major research challenges in cardiovascular disease and stroke that have the potential to produce an unusually high impact. (constantcontact.com)
Meningeal lymphatic4
- In this study, we used dynamic contrast-enhanced magnetic resonance imaging to assess meningeal lymphatic flow in cognitively normal controls and patients with idiopathic PD (iPD) or atypical Parkinsonian (AP) disorders. (lu.se)
- We found that patients with iPD exhibited significantly reduced flow through the meningeal lymphatic vessels (mLVs) along the superior sagittal sinus and sigmoid sinus, as well as a notable delay in deep cervical lymph node perfusion, compared to patients with AP. (lu.se)
- Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era? (northwestern.edu)
- Dive into the research topics of 'Correction: APOE4-mediated Alzheimer disease and "Vascular"-"Meningeal Lymphatic" components: towards a novel therapeutic era? (northwestern.edu)
20208
- The third sustainable development goal calls for elimination of neglected tropical diseases, including filariasis, by 2020. (bmj.com)
- In 1997, WHO and its Member States made a commitment to eliminate Lymphatic Filariasis (LF) as public health problem by 2020 through World Health Assembly Resolution WHA 50.29. (mohfw.gov.in)
- In 1997, The World Health Assembly adopted resolution WHA 50.29, for Elimination of Lymphatic Filariasis as a global public health problem by 2020. (mohfw.gov.in)
- Building on the success of previous years, the 2020 Gordon Research Conference on Lymphatics will be preceded by a Gordon Research Seminar on Lymphatics, themed "Interdisciplinary Perspectives on Lymphatic Function in Neglected Diseases" and organized by Elizabeth Haining and Rene Haegerling. (grc.org)
- We invite you to join us in Ventura, CA, in March 2020 for the preeminent lymphatic vessel meeting of the year! (grc.org)
- There are growing demands for predicting the prospects of achieving the global elimination of neglected tropical diseases as a result of the institution of large-scale nation-wide intervention programs by the WHO-set target year of 2020. (biomedcentral.com)
- We describe a modeling platform that addresses this problem of upscaling from local settings to facilitate predictions at regional levels by the discovery and use of locality-specific transmission models, and we illustrate the utility of using this approach to evaluate the prospects for eliminating the vector-borne disease, lymphatic filariasis (LF), in sub-Saharan Africa by the WHO target year of 2020 using currently applied or newly proposed intervention strategies. (biomedcentral.com)
- Partly, this is in response to the urgent policy demands for more accurate scientific information for determining if the roadmap set by the World Health Organization (WHO), based on sustaining and expanding drug access programs, will accomplish the elimination or control of these neglected tropical diseases (NTDs) by the target year of 2020 [ 6 ]. (biomedcentral.com)
Drainage1
- Lymphatic malformations are rare malformations of segregated lymphatic tissues that have not developed into lymphatic tissues with normal connections of regional lymphatic drainage and have resulted in dilatation of abnormal channels. (medscape.com)
Disorders1
- The workshop aims to improve how we manage and treat lymphatic disorders. (nih.gov)
Elimination11
- The prequalification is a crucial milestone that will see Eisai deliver "Eisai-original," high-quality DEC tablets to 250 million people living in at-risk communities in countries where lymphatic filariasis is endemic, thereby contributing to successful elimination of the disease. (eisai.com)
- The National Health Policy (2002) has set the goal of Elimination of Lymphatic Filariasis in India by 2015. (mohfw.gov.in)
- Twin pillar strategies of Mass Drug Administration (MDA) for interruption of transmission i.e. no new case and Morbidity Management and Disability Prevention (MMDP) for catering the disease afflicted patients were adopted for elimination. (mohfw.gov.in)
- Accelerated Plan which include Triple Drug Therapy (IDA) was launched in the Global Alliance Elimination of Lymphatic Filariasis (GAELF) meeting held during 13th to 15th June 2018 by Hon'ble Union Health Minister and Hon'ble Minister of State. (mohfw.gov.in)
- Meeting for Dissemination of the Accelerated Plan for Elimination of Lymphatic Filariasis and Program Progress Review held at New Delhi. (mohfw.gov.in)
- In 2004, Elimination of Lymphatic Filariasis (ELF) programme was launched covering 202 endemic districts in 20 States/UTs. (mohfw.gov.in)
- The policy decision to implement global strategy of co-administration of DEC with Albendazole during MDA was approved by National Task Force on Elimination of Lymphatic Filariasis under the Chairmanship of DGHS in 2006. (mohfw.gov.in)
- Fostering continual innovation in diagnostics, treatment, and prevention is critical to meet the changing demands of disease elimination programmes. (bmj.com)
- Expanding treatment options alongside ensuring high coverage of mass drug administration can accelerate progress in elimination of lymphatic filarisis, say Sabine Specht and colleagues. (bmj.com)
- Zakir Thomas and colleagues call for a comprehensive policy for neglected diseases research in India to foster innovation in drugs, diagnostics, and vaccines, critical for evolving needs of elimination programmes. (bmj.com)
- Monitoring and epidemiological assessment of mass drug administration in the global programme to eliminate lymphatic filariasis : a manual for national elimination programmes. (who.int)
Inflammation2
- In autoimmune connective tissue diseases, the immune system attacks healthy connective tissue, causing inflammation and damage. (medicalnewstoday.com)
- Chronic inflammation caused by the immune response can lead to the thickening of the walls of the lymphatic vessels and reduced lymphatic flow. (who.int)
Vasculature1
- The lymphatic vasculature has garnered immense attention over the last decade, fueled by advances in our ability to recognize and manipulate lymphatic vessels, together with discoveries that have illuminated key roles for the lymphatic vasculature in human health and disease. (grc.org)
Infectious5
- Is lymphatic filariasis an emerging infectious disease? (themedicalquestions.com)
- Given that infectious diseases do not respect borders, this initiative seems an excellent opportunity for collaboration between Haiti and the Dominican Republic. (haitiinnovation.org)
- Neglected tropical diseases (NTDs) are a group of infectious diseases that thrive in poor and rural settings, affecting 1.6 billion of the world's poorest and most vulnerable people, including 850 million children. (kit.nl)
- Neglected tropical diseases mainly comprise infectious diseases seen in subtropical and tropical regions. (bmj.com)
- Communicable, or infectious diseases, are caused by microorganisms such as bacteria, viruses, parasites and fungi that can be spread, directly or indirectly, from one person to another. (who.int)
Tissue13
- In cystic hygroma (shown in the ultrasonograms below), cavernous lymphatic spaces communicate and grow to form large cysts that can infiltrate the surrounding tissue. (medscape.com)
- Get a clear understanding of how the lymphatic system functions, from lymphatic capillaries to collecting lymphatic vessels, and their crucial role in maintaining tissue balance. (lgdalliance.org)
- Diagnosis is by detection of microfilariae in blood or lymphatic tissue biopsy specimens, ultrasound visualization of adult worms in lymphatics, or serologic testing. (msdmanuals.com)
- The _____ is the largest mass of lymphatic tissue in the body and is found in the left hypochondriac region between the fundus of the stomach and the diaphram. (easynotecards.com)
- Diseases that affect the function or structure of connective tissue are known as connective tissue diseases. (medicalnewstoday.com)
- Continue reading to learn more about the different types of connective tissue diseases and their symptoms. (medicalnewstoday.com)
- What are connective tissue diseases? (medicalnewstoday.com)
- Connective tissue diseases are diseases that affect the function or structure of connective tissue. (medicalnewstoday.com)
- Many diseases can cause problems with this type of tissue. (medicalnewstoday.com)
- Inherited connective tissue diseases occur as a result of genetics. (medicalnewstoday.com)
- If a person inherits a gene that tells their body to make these proteins in an atypical way, the person may have a connective tissue disease from birth. (medicalnewstoday.com)
- Sometimes, a gene may change during or after pregnancy, resulting in a child having a sporadic genetic connective tissue disease when no family history of the condition exists. (medicalnewstoday.com)
- If a person has symptoms of more than one of these conditions, they may have mixed connective tissue disease. (medicalnewstoday.com)
Parasitic disease3
- Lymphatic filariasis is a parasitic disease caused by microscopic, thread-like worms. (themedicalquestions.com)
- Lymphatic filariasis is a parasitic disease that is transmitted to humans by the bite of a mosquito. (eisai.com)
- We show how a computational platform that couples site-specific data discovery with model fitting and calibration can allow both learning of local LF transmission models and simulations of the impact of interventions that take a fuller account of the fine-scale heterogeneous transmission of this parasitic disease within endemic countries. (biomedcentral.com)
NTDs3
- In May 2013, the World Health Assembly passed resolution WHA66.12 reinforcing progress towards coordination among programmes directed against different neglected tropical diseases (NTDs). (who.int)
- Please refer to the following notes for further information on NTDs, lymphatic filariasis, the London Declaration on NTDs, and the WHO Prequalification of Medicines Programme. (eisai.com)
- There are 149 countries and territories where NTDs are endemic, at least 100 of which are endemic for 2 or more of these diseases, and 30 countries and territories that are endemic for 6 or more. (eisai.com)
India3
- India alone harbours 40% of the world's burden of disease. (bmj.com)
- Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito, "Eisai") announced today that it has received prequalification from the World Health Organization (WHO) for diethylcarbamazine citrate (DEC) 100 mg tablets manufactured at its Vizag Plant in India for the treatment of lymphatic filariasis, a neglected tropical disease (NTD). (eisai.com)
- Can India lead the way in neglected diseases innovation? (bmj.com)
Interstitial fluid2
- In physiological conditions, the main functions assigned to the lymphatic system are the maintenance of the interstitial fluid homeostasis, immune surveillance and the absorption of dietary fat in the intestine (Alitalo, 2011). (uma.es)
- Interstitial fluid drains into lymphatic capillaries, thus forming lymph. (easynotecards.com)
Filarial2
- Chronic filarial disease develops insidiously after many years. (msdmanuals.com)
- Globally, approximately 40 million people are affected by the clinical manifestations of lymphatic filariasis (LF), which ranges from acute attacks of filarial fever (acute dermatolymphangioadenitis or ADLAs) to chronic manifestations of lymphoedema and hydrocoele [ 1 ]. (biomedcentral.com)
Eliminate6
- This manual is designed to teach personnel of national programmes to eliminate lymphatic filariasis (LF), including regional and district health personnel, the essential elements of monitoring and evaluating national programmes to eliminate LF. (who.int)
- The World Health Organization launched the global programme to eliminate lymphatic filariasis in 2000. (bmj.com)
- Subsequent to that Global Alliance to Eliminate Lymphatic Filariasis (GAELF) has been formed in 2000. (mohfw.gov.in)
- For high level advocay - United to Eliminate Lymphatic National Symposium Filariasis held on 30th October 2019 at Pravasi Bharatiya Kendra, New Delhi inaugurated by Hon'ble Union Health Minister. (mohfw.gov.in)
- Managing morbidity and preventing disability amongst those already affected by LF is one of the main components of the Global Programme to Eliminate Lymphatic Filariasis (GPELF), and as such effective morbidity management strategies are vital for public health improvement. (biomedcentral.com)
- The New York Times recently carried an article on the Carter Center's joint Haiti/Dominican Republic initiative to eliminate malaria and lymphatic filariasis from the island of Hispaniola, which both countries share. (haitiinnovation.org)
Fluid7
- In the kidneys, the lymphatics help remove excess fluid and macromolecules to maintain proper kidney function, and to contribute to kidney immunity and responses after injuries. (yale.edu)
- The lymphatic system is a crucial component of nutrient and hormone absorption, fluid homeostasis and immunity. (nih.gov)
- The lymphatic system provides another route by which fluid can flow from distant tissues back into the blood stream, one that is separate from capillaries and veins. (petplace.com)
- The blood and lymphatic vascular systems are essential for the efficient transport of oxygen, nutrients, signaling molecules, and leukocytes to and from peripheral tissues, the removal of waste products, and the preservation of fluid homeostasis. (nature.com)
- Traditionally, microcirculatory physiologists studied the essential transport functions of lymphatic vessels in removing fluid, molecules, and cells after leaking from blood vessels in the periphery and before returning them to the blood circulation. (jci.org)
- The lymphatic system runs parallel to the circulatory system, and lymphatic vessels carry fluid throughout the body. (remedypost.com)
- The lymphatic system is a crucial part of the immune system, helping to maintain overall health by removing waste and regulating fluid balance. (remedypost.com)
Diagnosis4
- Information concerning the extent of the disease at the time of diagnosis was available in 75 cases. (nih.gov)
- Historically, the American Thoracic Society (ATS) and the Centers for Disease Control (CDC) have provided guidance on the diagnosis, treatment, prevention, and control of tuberculosis in the United States and Canada. (cdc.gov)
- This revision has been made primarily to update the information on tuberculin skin testing and laboratory services for the diagnosis of tuberculosis, and to remove material pertaining to nontuberculous mycobacterial diseases, which will henceforth be dealt with separately. (cdc.gov)
- In some populations, we suspect that possibility of death increases because poor access to health care services might delay diagnosis, resulting in more severe disease. (cdc.gov)
Endemic countries1
- In endemic countries, lymphatic filariasis has a major social and economic impact. (who.int)
Symptoms2
- Other individuals have a multitude of the most severe symptoms of end-stage liver disease and a limited chance for survival. (medscape.com)
- Specific medical therapies may be applied to many liver diseases in an effort to diminish symptoms and to prevent or forestall the development of cirrhosis. (medscape.com)
Chronic4
- Increasing evidence suggests that excessive lymphangiogenesis could be harmful in acute kidney injury, chronic kidney disease, and kidney transplant rejection, thus making it an area of active research. (yale.edu)
- Adenolymphangitis episodes usually precede onset of chronic disease by ≥ 2 decades. (msdmanuals.com)
- Because it is a chronic disease people can go years without treatment, so it is important to monitor the disease for any changes. (cancercare.org)
- CT thorax scan of a 77-year-old woman who presented with chronic cough and sputum production, without a history of underlying preexisting lung disease. (medscape.com)
Lymphangiogenesis2
Malformation1
- Cystic hygroma belongs to a group of diseases recognized as lymphatic malformations and is also known as macrocystic lymphatic malformation or cystic lymphangioma . (medscape.com)
Spleen1
- The spleen is the largest body of lymphatic system. (petplace.com)
Mosquito2
- Infective larvae from the mosquito migrate to the lymphatics, where they develop into threadlike adult worms within 6 to 12 months. (msdmanuals.com)
- Efforts to control lymphatic filariasis include mosquito control, mass drug administration to reduce transmission and treatment of individual cases. (who.int)
Mass drug administration2
- Annual Mass Drug Administration (MDA) of single dose of DEC (Diethylcarbamazine citrate) and Albendazole for 5 years or more to the eligible population (except pregnant women, children below 2 years of age and seriously ill persons) to interrupt transmission of the disease. (mohfw.gov.in)
- AbstractBackgroundIn view of the current global COVID-19 pandemic, mass drug administration interventions for neglected tropical diseases, including lymphatic filariasis, have been halted. (ox.ac.uk)
Tissues1
- The lymphatic system plays an important role in uptake of dietary fat and clearance of cholesterol from peripheral tissues and has been implicated in several disease states such as obesity, metabolic syndrome and inflammatory bowel disease (IBD). (nih.gov)
Programmes2
- The status of the disease control programmes in Egypt, Sudan and Yemen was discussed during the meeting. (who.int)
- This collection of articles highlights successes of public health programmes for these and other neglected diseases in South Asia and explores outstanding issues requiring supportive policy and research. (bmj.com)
Person's2
- A person's lymphatic system is part of their immune system . (medicalnewstoday.com)
- Because tuberculosis, even after it has been treated adequately, remains a pertinent and lifelong part of a person's medical history, previous as well as current disease is included in the classification. (cdc.gov)
Cancer3
- Diseases and disorder Hodgkin's Disease/Hodgkin's Lymphoma Hodgkin lymphoma This is a type of cancer of the lymphatic system. (wikipedia.org)
- Other lymphatic system problems can include infections, blockage, and cancer . (medlineplus.gov)
- Many cancer cells are spread by way of the lymphatic system, producing cluster of tumor cells where they lodge. (easynotecards.com)
Blood8
- Similar to the blood circulatory system, the lymphatic system is comprised of fine channels that lie adjacent to the blood vessels. (petplace.com)
- We determine a comprehensive map of lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs), combining RNA-Seq and CAGE-Seq. (nature.com)
- In contrast, lymphatic vasculogenesis starts after the establishment of the blood circulatory system. (nature.com)
- Therefore, this complex regulatory network requires precise control of gene expression patterns at both transcriptional and post-transcriptional levels in order to ensure proper maturation, differentiation, and formation of blood and lymphatic vessels. (nature.com)
- The presence of lymphatic and blood vessels in oral squamous cell carcinoma (OSCC) should play a key role in progression and dissemination. (bvsalud.org)
- This study aimed to evaluate the correlation between the lymphatic and blood vessel densities with prognostic outcomes in advanced stage OSCC. (bvsalud.org)
- The lymphatic vascular density (LVD), blood vascular density (BVD), and neoformed vascular density (NVD) were assessed by counting positive reactions in 4 hotspot areas, both intratumoral (IT) and peritumoral (PT), at high magnification (× 40). (bvsalud.org)
- The penile shaft is composed of 3 erectile columns, the 2 corpora cavernosa and the corpus spongiosum, as well as the columns' enveloping fascial layers, nerves, lymphatics, and blood vessels, all covered by skin (see the following images). (medscape.com)
Manifestations1
- Lymphoedema and hydrocoele are the two most common clinical manifestations of lymphatic filariasis (LF). (biomedcentral.com)
20001
- In 2000, annual mass administration of diethlycarbamazine and albendazole began in Leogane Commune, Haiti, to interrupt transmission of lymphatic filariasis (LF). (cdc.gov)
Called the1
- These lymphatic vessels eventually merge into a rather large vessel called the thoracic duct. (petplace.com)
Immune functions3
- In the digestive system, lymphatic vessel function is interwoven with organ function, both anatomically and physiologically and these vessels lie at the nexus of critical hormonal, digestive and immune functions. (nih.gov)
- A dog's lymphatic system is a complex and vital system primarily responsible for the transportation of lymph and for participating in many immune functions of the body. (petplace.com)
- These new ideas, in turn, reveal a paradigm whereby the transport and immune functions of lymphatic vessels, which were previously considered separately, are in fact intimately coupled. (jci.org)
Centers7
- Centers for Disease Control and Prevention. (cdc.gov)
- Protocols for collecting data from sentinel sites were approved by the Centers for Disease Control and Prevention Institutional Review Board and the Ethics Committee at Hopital Ste. Croix. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- This is a joint statement of the American Thoracic Society and the Centers for Disease Control. (cdc.gov)
- The US Centers for Disease Control and Prevention (CDC) surveillance data from Houston and Atlanta suggest an incidence of 1 case per 100,000 persons per year. (medscape.com)
- Announcer] This program is presented by the Centers for Disease Control and Prevention. (cdc.gov)
- Kapil and I come to you from the Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry in Atlanta, Georgia. (cdc.gov)
Circulatory system1
- The lymphatic system is part of the circulatory system and it is indispensable for life. (uma.es)
Humans1
- LF is a disease that is transmitted by mosquitoes that bite infected humans and pick up microfilariae - thread like parasitic worms. (haitiinnovation.org)