Necrosis of bone following radiation injury.
'Mandibular diseases' refer to various medical conditions that primarily affect the structure, function, or health of the mandible (lower jawbone), including but not limited to infections, tumors, developmental disorders, and degenerative diseases.
'Jaw diseases' is a broad term referring to various medical conditions affecting the temporomandibular joint, jawbones, or the surrounding muscles, including but not limited to dental disorders, jaw fractures, tumors, infections, and developmental abnormalities.
The therapeutic intermittent administration of oxygen in a chamber at greater than sea-level atmospheric pressures (three atmospheres). It is considered effective treatment for air and gas embolisms, smoke inhalation, acute carbon monoxide poisoning, caisson disease, clostridial gangrene, etc. (From Segen, Dictionary of Modern Medicine, 1992). The list of treatment modalities includes stroke.
Intraoral OSTEOTOMY of the lower jaw usually performed in order to correct MALOCCLUSION.
The surgical removal of a tooth. (Dorland, 28th ed)
Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.
Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES.
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.

A large maxillofacial prosthesis for total mandibular defect: a case report. (1/56)

We successfully fabricated a large maxillofacial prosthesis for replacement of a total mandibular defect resulting from surgical failure to reconstruct the mandible. Although a number of reports have described procedures for fabricating midfacial prostheses, there is little information on prostheses to compensate for total loss of the mandible. A 54-year-old woman was referred to the Dentistry and Oral Surgery Division of the National Cancer Center Hospital with total loss of the mandible and the surrounding facial soft tissue. The facial prosthesis we used to treat this patient is unique in that it is adequately retained without the use of extraoral implants and conventional adhesives. This prosthesis is retained by the bilateral auricles and the remaining upper front teeth. We present details of the design of this large silicone maxillofacial prosthesis, with which we successfully rehabilitated the patient.  (+info)

Masticator space abnormalities associated with mandibular osteoradionecrosis: MR and CT findings in five patients. (2/56)

BACKGROUND AND PURPOSE: Imaging of patients with a clinical diagnosis of mandibular osteoradionecrosis (ORN) is often performed to support that clinical suspicion, evaluate the extent of the disease, or exclude coexistent tumor recurrence. The purpose of our study was to describe the clinical, MR imaging, and CT features of five patients with mandibular ORN associated with prominent soft-tissue abnormality in the adjacent masticator muscles. METHODS: The MR and CT examinations of five patients with mandibular ORN associated with soft-tissue abnormalities in the adjacent masticator muscles were reviewed. All patients had received external beam radiotherapy for primary head and neck malignancies, with a total radiation dose range of 60 Gy to 69 Gy in 30 to 38 fractions. RESULTS: CT revealed the typical osseous findings of cortical disruption, trabecular disorganization, and fragmentation in all five patients. Abnormal diffuse enhancement of the adjacent masseter and pterygoid muscles was noted in all patients. Four patients had prominent mass-like thickening of these muscles adjacent to the osseous abnormality. Of the three patients who underwent MR imaging, all showed homogeneous abnormal T1 hypointensity, T2 hyperintensity, and intense enhancement of the bone marrow in the involved mandible. The masticator muscles adjacent to the osseous abnormality also showed abnormal T2 hyperintensity and intense diffuse enhancement on MR images. CONCLUSION: Mandibular ORN can be associated with prominent soft-tissue thickening and enhancement in the adjacent musculature. These changes can appear mass-like and are not related to tumor recurrence or metastatic disease.  (+info)

Possibilities of preventing osteoradionecrosis during complex therapy of tumors of the oral cavity. (3/56)

In recent years, there has been a dramatic increase in the number of tumors of the head and neck. Their successful treatment is one of the greatest challenges for physicians dealing with oncotherapy. An organic part of the complex therapy is preoperative or postoperative irradiation. Application of this is accompanied by a lower risk of recurrences, and by a higher proportion of cured patients. Unfortunately, irradiation also has a disadvantage: the development of osteoradionecrosis, a special form of osteomyelitis, in some patients (mainly in those cases where irradiation occurs after bone resection or after partial removal of the periosteum). Once the clinical picture of this irradiation complication has developed, its treatment is very difficult. A significant result or complete freedom from complaints can be attained only rarely. Attention must therefore be focussed primarily on prevention, and the oral surgeon, the oncoradiologist and the patient too can all do much to help prevent the occurrence of osteoradionecrosis. Through coupling of an up-to-date, functional surgical attitude with knowledge relating to modern radiology and radiation physics, the way may be opened to forestall this complication that is so difficult to cure.  (+info)

Osteoradionecrosis of the mandible. (4/56)

Osteoradionecrosis is a major complication of surgery or trauma in previously irradiated bone in the absence of tumor persistence. Radiation-induced vascular insufficiency rather than infection causes bone death. It occurs most commonly in the mandible after head and neck irradiation. Risk factors include the total radiation dose, modality of treatment, fraction size and dose rate, oral hygiene, timing of tooth extractions as well as the continued use of tobacco and alcohol. This condition is often painful, debilitating, and may result in significant bone loss. The recommended treatment guidelines are irrigation, antibiotics, hyperbaric oxygen therapy, and surgical techniques, including hemimandibulectomy and graft placements.  (+info)

Hyperbaric oxygen therapy and mandibular osteoradionecrosis: a retrospective study and analysis of treatment outcomes. (5/56)

BACKGROUND: Hyperbaric oxygen (HBO) therapy is recognized as an adjunctive treatment for osteoradionecrosis (ORN). It may also be used prophylactically in patients who require dental extractions and are at high risk for developing ORN. This article reviews the treatment outcomes of patients treated with HBO therapy at the Toronto General Hospital from 1985 to 1997. MATERIALS AND METHODS: A total of 297 charts of patients treated with HBO were reviewed. Criteria assessed included age of patient, gender, original diagnosis, radiation dose, time between radiation treatment and onset of ORN, presence or absence of fracture, orocutaneous fistula, pain, history of a precipitating event triggering ORN, medical status, HBO therapy (total oxygen time, number of dives), method of treatment of ORN and follow-up period. Minimum patient follow-up time for inclusion in the study was 6 months. RESULTS: Adequate information to meet the inclusion criteria was obtained for 75 patients. Group A (51 patients) had been treated for overt ORN with HBO alone, HBO with sequestrectomy, or HBO with sequestrectomy and reconstruction. Group B (24 patients at risk for developing ORN) had been treated with HBO prophylactically for dental extractions. In group A, only 3 patients (5.9%) failed to show improvement. In group B, only one patient (4.2%) had complications during healing. CONCLUSIONS: Encouraging results were achieved when HBO was used in the 2 groups described above. This paper supports existing literature on the potential benefit of HBO as a prophylactic agent and adjunctive treatment of ORN.  (+info)

A survey of antibiotic prescribing by maxillofacial consultants for dental extractions following radiotherapy to the oral cavity. (6/56)

OBJECTIVES: To analyse the antibiotic prescribing trends for exodontia and minor oral surgery in patients with a history of radiotherapy. Also, to evaluate the use of hyperbaric oxygen as a separate modality in the prevention of osteoradionecrosis. DESIGN: A survey of antibiotic prescribing involving the analysis of a questionnaire which included the management of three patients with a history of head and neck malignancy. METHOD: The heads of the departments in each unit in the UK were sent a closed-response questionnaire. Antibiotic prescribing was assessed in three case scenarios. Case one referred to a patient that had surgery alone as part of the management of head and neck cancer, who needed the surgical removal of second molar roots. Case two referred to a patient that had surgery and adjuvant radiotherapy as part of the management of head and neck cancer, and needed the same procedure as in case one. Case three included a patient with a history of surgery and adjuvant radiotherapy, who required the extraction of three mobile and periodontally-involved lower incisors. Consultants were also asked about the use of hyperbaric oxygen in the patients who had radiotherapy as part of their treatment strategy. RESULTS: A total of 109 questionnaires were sent to all the Maxillofacial Units in the UK. The response rate was 73%. In patients with a history of radical surgery alone for the management of head and neck cancer, 20% of the surgeons advocated pre-operative antibiotics for the surgical removal of lower posterior teeth. In contrast, in the patient with a history of adjuvant radiotherapy 86% supported pre-operative antimicrobial use for the surgical removal of the same teeth. In the extraction of mobile and periodontally involved lower incisors in the previously irradiated patient, 63% of the clinicians supported pre-extraction antibiotics. Postoperative antibiotics were advocated in 52% in the first case, 89% in the second case and 71% in the third case. 34% of the clinicians advocated hyperbaric oxygen for surgical removal of posterior teeth and 15% for the extraction of mobile anterior teeth. CONCLUSIONS: The use of peri-extraction antibiotics was favoured among oral and maxillofacial surgeons. There was little enthusiasm towards the use of hyperbaric oxygen as a prophylactic measure, alone or in conjunction with an antimicrobial regime. Control randomised trials that will measure the effectiveness of hyperbaric oxygen and the appropriate use of antibiotics for prophylaxis in pre- and post-operative regimes are necessary to evaluate the use of these modalities.  (+info)

Therapeutic use of hyperbaric oxygen for irradiated dental implant patients: a systematic review. (7/56)

The aim of this systematic review was to investigate the effectiveness of hyperbaric oxygen (HBO) therapy for irradiated patients who require dental implants using data from randomized controlled clinical trials (RCTs). The review was prepared according to Cochrane Collaboration guidelines. The Cochrane Oral Health Group Specialist Register and the Cochrane Controlled Trials Register were searched (Cochrane Library 2002, Issue 2), together with Medline from 1966 or Embase from 1974. Several journals were hand-searched, and fifty-five implant manufacturers were contacted in an attempt to identify ongoing or unpublished studies. The results were that no RCTs comparing HBO with no HBO for implant treatment in irradiated patients were identified. Our principal conclusions are that clinicians ought to be aware and make patients aware of the lack of reliable clinical evidence for or against the clinical effectiveness of HBO therapy in irradiated patients requiring dental implants. There is a need for RCTs to determine the effectiveness of HBO.  (+info)

Ultrasound stimulation of maxillofacial bone healing. (8/56)

A substantial part of the maxillofacial surgery practice deals with maxillofacial bone healing. In the past decades, low-intensity ultrasound treatment has been shown to reduce the healing time of fresh fractures of the extremities up to 38%, and to heal delayed and non-unions up to 90% and 83%, respectively. Based on the assumption that the process of bone healing in the bones of the extremities and maxillofacial skeleton is essentially the same, the potential of ultrasound to stimulate maxillofacial bone healing was investigated. Although limited evidence is available to support the susceptibility of maxillofacial bone to the ultrasound signal, ultrasound may be of value in the treatment of delayed unions, in callus maturation after distraction, and in the treatment of osteoradionecrosis.  (+info)

Osteoradionecrosis (ORN) is a serious and potentially disabling complication of radiation therapy, particularly in the head and neck region. It is defined as an area of exposed necrotic bone that fails to heal over a period of 3-6 months in a patient who has received radiation therapy. The pathophysiology of ORN involves damage to blood vessels, connective tissue, and bone, leading to hypoxia, hypocellularity, and hypovascularity.

The clinical presentation of ORN includes pain, swelling, trismus (difficulty opening the mouth), foul odor, and purulent drainage. The diagnosis is typically made based on clinical examination and imaging studies such as CT or MRI scans. Treatment options for ORN include hyperbaric oxygen therapy, surgical debridement, and antibiotic therapy. Preventive measures include good oral hygiene, dental evaluation before radiation therapy, and avoidance of tobacco and alcohol use.

Mandibular diseases refer to conditions that affect the mandible, or lower jawbone. These diseases can be classified as congenital (present at birth) or acquired (developing after birth). They can also be categorized based on the tissues involved, such as bone, muscle, or cartilage. Some examples of mandibular diseases include:

1. Mandibular fractures: These are breaks in the lower jawbone that can result from trauma or injury.
2. Osteomyelitis: This is an infection of the bone and surrounding tissues, which can affect the mandible.
3. Temporomandibular joint (TMJ) disorders: These are conditions that affect the joint that connects the jawbone to the skull, causing pain and limited movement.
4. Mandibular tumors: These are abnormal growths that can be benign or malignant, and can develop in any of the tissues of the mandible.
5. Osteonecrosis: This is a condition where the bone tissue dies due to lack of blood supply, which can affect the mandible.
6. Cleft lip and palate: This is a congenital deformity that affects the development of the face and mouth, including the lower jawbone.
7. Mandibular hypoplasia: This is a condition where the lower jawbone does not develop properly, leading to a small or recessed chin.
8. Developmental disorders: These are conditions that affect the growth and development of the mandible, such as condylar hyperplasia or hemifacial microsomia.

Jaw diseases refer to a variety of conditions that affect the temporomandibular joint (TMJ) and the surrounding muscles, as well as dental disorders that can impact the jaw. Some common examples include:

1. Temporomandibular Joint Disorders (TMD): These are problems with the TMJ and the muscles that control jaw movement. Symptoms may include pain, clicking or popping sounds, and limited movement of the jaw.

2. Osteonecrosis of the Jaw: This is a condition where bone in the jaw dies due to lack of blood supply. It can be caused by radiation therapy, chemotherapy, or certain medications.

3. Dental Cavities: These are holes in the teeth caused by bacteria. If left untreated, they can cause pain, infection, and damage to the jawbone.

4. Periodontal Disease: This is an infection of the gums and bones that support the teeth. Advanced periodontal disease can lead to loss of teeth and damage to the jawbone.

5. Jaw Fractures: These are breaks in the jawbone, often caused by trauma.

6. Oral Cancer: This is a type of cancer that starts in the mouth or throat. If not treated early, it can spread to the jaw and other parts of the body.

7. Cysts and Tumors: These are abnormal growths in the jawbone or surrounding tissues. While some are benign (non-cancerous), others can be malignant (cancerous).

8. Osteomyelitis: This is an infection of the bone, often occurring in the lower jaw. It can cause pain, swelling, and fever.

9. Oral Thrush: This is a fungal infection that causes white patches on the inside of the mouth. If left untreated, it can spread to the jaw and other parts of the body.

10. Sinusitis: Inflammation of the sinuses can sometimes cause pain in the upper jaw.

Hyperbaric oxygenation is a medical treatment in which a patient breathes pure oxygen in a pressurized chamber, typically at greater than one atmosphere absolute (ATA). This process results in increased levels of oxygen being dissolved in the blood and delivered to body tissues, thereby promoting healing, reducing inflammation, and combating infection. Hyperbaric oxygen therapy is used to treat various medical conditions, including carbon monoxide poisoning, decompression sickness, gangrene, and wounds that are slow to heal due to diabetes or radiation injury.

A mandibular osteotomy is a surgical procedure that involves making a cut in the mandible (lower jawbone). This procedure is often performed to correct various dental and maxillofacial conditions such as jaw misalignment, sleep apnea, or jaw tumors. The specific type of osteotomy performed depends on the individual patient's needs and may involve making cuts at different locations along the mandible.

During the procedure, the surgeon makes an incision in the gum tissue to expose the mandible and then uses specialized instruments to make a precise cut in the bone. The surgeon can then move the jawbone into the desired position and secure it with plates, screws, or wires. In some cases, bone grafting may also be necessary to provide additional support.

After the procedure, patients may experience swelling, bruising, and discomfort, which can be managed with pain medication and cold compresses. Patients are usually advised to follow a soft diet for several weeks while the jaw heals. The recovery period can vary depending on the individual patient's healing process, but most patients can return to their normal activities within a few weeks.

Tooth extraction is a dental procedure in which a tooth that is damaged or poses a threat to oral health is removed from its socket in the jawbone. This may be necessary due to various reasons such as severe tooth decay, gum disease, fractured teeth, crowded teeth, or for orthodontic treatment purposes. The procedure is performed by a dentist or an oral surgeon, under local anesthesia to numb the area around the tooth, ensuring minimal discomfort during the extraction process.

A surgical flap is a specialized type of surgical procedure where a section of living tissue (including skin, fat, muscle, and/or blood vessels) is lifted from its original site and moved to another location, while still maintaining a blood supply through its attached pedicle. This technique allows the surgeon to cover and reconstruct defects or wounds that cannot be closed easily with simple suturing or stapling.

Surgical flaps can be classified based on their vascularity, type of tissue involved, or method of transfer. The choice of using a specific type of surgical flap depends on the location and size of the defect, the patient's overall health, and the surgeon's expertise. Some common types of surgical flaps include:

1. Random-pattern flaps: These flaps are based on random blood vessels within the tissue and are typically used for smaller defects in areas with good vascularity, such as the face or scalp.
2. Axial pattern flaps: These flaps are designed based on a known major blood vessel and its branches, allowing them to cover larger defects or reach distant sites. Examples include the radial forearm flap and the anterolateral thigh flap.
3. Local flaps: These flaps involve tissue adjacent to the wound and can be further classified into advancement, rotation, transposition, and interpolation flaps based on their movement and orientation.
4. Distant flaps: These flaps are harvested from a distant site and then transferred to the defect after being tunneled beneath the skin or through a separate incision. Examples include the groin flap and the latissimus dorsi flap.
5. Free flaps: In these flaps, the tissue is completely detached from its original blood supply and then reattached at the new site using microvascular surgical techniques. This allows for greater flexibility in terms of reach and placement but requires specialized expertise and equipment.

Surgical flaps play a crucial role in reconstructive surgery, helping to restore form and function after trauma, tumor removal, or other conditions that result in tissue loss.

Radiation injuries refer to the damages that occur to living tissues as a result of exposure to ionizing radiation. These injuries can be acute, occurring soon after exposure to high levels of radiation, or chronic, developing over a longer period after exposure to lower levels of radiation. The severity and type of injury depend on the dose and duration of exposure, as well as the specific tissues affected.

Acute radiation syndrome (ARS), also known as radiation sickness, is the most severe form of acute radiation injury. It can cause symptoms such as nausea, vomiting, diarrhea, fatigue, fever, and skin burns. In more severe cases, it can lead to neurological damage, hemorrhage, infection, and death.

Chronic radiation injuries, on the other hand, may not appear until months or even years after exposure. They can cause a range of symptoms, including fatigue, weakness, skin changes, cataracts, reduced fertility, and an increased risk of cancer.

Radiation injuries can be treated with supportive care, such as fluids and electrolytes replacement, antibiotics, wound care, and blood transfusions. In some cases, surgery may be necessary to remove damaged tissue or control bleeding. Prevention is the best approach to radiation injuries, which includes limiting exposure through proper protective measures and monitoring radiation levels in the environment.

The mandible, also known as the lower jaw, is the largest and strongest bone in the human face. It forms the lower portion of the oral cavity and plays a crucial role in various functions such as mastication (chewing), speaking, and swallowing. The mandible is a U-shaped bone that consists of a horizontal part called the body and two vertical parts called rami.

The mandible articulates with the skull at the temporomandibular joints (TMJs) located in front of each ear, allowing for movements like opening and closing the mouth, protrusion, retraction, and side-to-side movement. The mandible contains the lower teeth sockets called alveolar processes, which hold the lower teeth in place.

In medical terminology, the term "mandible" refers specifically to this bone and its associated structures.

Risk factors for osteoradionecrosis include: Size and location of tumor; the risk of developing ORN increases with larger ... Osteoradionecrosis is difficult to prevent and treat. Current prevention strategies are aimed at avoiding excess doses of ... Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes ... The epidemiology of osteoradionecrosis has proven difficult to estimate, with previous studies reporting incidence of disease ...
In 2014, she started suffering from Osteoradionecrosis, jawbone death, because of the radiotherapy. The Swedish surgeons said ...
... accelerated atherosclerosis in patients with osteoradionecrosis by panoramic radiography". Journal of Oral and Maxillofacial ...
Radiation necrosis most commonly presents as osteoradionecrosis, vaginal radionecrosis, soft tissue radionecrosis, or laryngeal ...
Complications of radiotherapy: Osteoradionecrosis may result in pain, trismus, suppuration and occasionally a foul smelling ...
Osteoradionecrosis is the term for when such an area of irradiated bone does not heal from this damage. This usually occurs in ...
... , in combination with tocopherol and clodronate, has been found to heal refractory osteoradionecrosis of the jaw ... and to be prophylactic against osteoradionecrosis. In a Cochrane systematic review on the use of pentoxifylline for ... "Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol- ...
EUBS projects in 2013 include research into the effect of hyperbaric oxygen treatment on osteoradionecrosis and on lower limb ...
Proving Dental Malpractice in a Case of Osteoradionecrosis Following Tooth Extraction, Medical Malpractice Law & Strategy Vol. ...
... and osteoradionecrosis, which occurs when radiation causes part of the bone in the jaw or skull base to die. Proton therapy has ...
Osteoradionecrosis OM can also be typed according to the area of the skeleton in which it is present. For example, ...
... see section on Bisphosphonates Osteoradionecrosis, a term for osteonecrosis caused by radiotherapy Phossy jaw Nase JB, Suzuki ...
... osteoradionecrosis MeSH C21.866.733.720 - radiation injuries, experimental MeSH C21.866.733.762 - radiation pneumonitis MeSH ...
... an amino acid that plays a role in the urea cycle Osteoradionecrosis, a complication of radiation therapy where a section of ...
Risk factors for osteoradionecrosis include: Size and location of tumor; the risk of developing ORN increases with larger ... Osteoradionecrosis is difficult to prevent and treat. Current prevention strategies are aimed at avoiding excess doses of ... Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes ... The epidemiology of osteoradionecrosis has proven difficult to estimate, with previous studies reporting incidence of disease ...
Osteoradionecrosis (ORN) is a condition of nonvital bone in a site of radiation injury. ORN can be spontaneous, but it most ... encoded search term (Osteoradionecrosis of the Mandible) and Osteoradionecrosis of the Mandible What to Read Next on Medscape ... Osteoradionecrosis of the Mandible. Updated: Sep 22, 2023 * Author: Remy H Blanchaert, Jr, DDS, MD; Chief Editor: Arlen D ... Osteoradionecrosis (ORN) is a condition of nonvital bone in a site of radiation injury. [1] ORN can be spontaneous, but it most ...
I am concerned about what I read about bone death due to RT, called Osteoradionecrosis. ... Osteoradionecrosis. While Osteoradionecrosis is a concern, you have to think that it may not happen and if it does, it may be ... Osteoradionecrosis While Osteoradionecrosis is a concern, you have to think that it may not happen and if it does, it may be ... Then, I had osteoradionecrosis very early in 2018 in my upper jaw (maxilla) I did not have tooth extraction or anything to ...
Osteoradionecrosis is a problem with bone healing, particularly in the jawbone. It can occur after high doses of radiation have ... What If I Have Osteoradionecrosis?. Treatment for osteoradionecrosis can help control its symptoms. Salt-water rinses and light ... Osteoradionecrosis After Childhood Cancer Home » Cancer Resources » Late Effects of Treatment for Childrens Cancer » ... Osteoradionecrosis can be diagnosed by physical examination and imaging studies. In some cases, a surgeon may need to take a ...
... whether low-intensity ultrasound accelerates healing in bone tissues close to dental implants with osteoradionecrosis (ORN) of ... Low-intensity ultrasound accelerates mandibular implant bone integration in dogs with mandibular osteoradionecrosis. ... Low-intensity ultrasound can accelerate the healing of bone tissues surrounding dental implants in osteoradionecrosis of the ... whether low-intensity ultrasound accelerates healing in bone tissues close to dental implants with osteoradionecrosis (ORN) of ...
"Osteoradionecrosis" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Osteoradionecrosis" by people in this website by year, and ... Below are the most recent publications written about "Osteoradionecrosis" by people in Profiles. ... whether "Osteoradionecrosis" was a major or minor topic of these publications. To see the data from this visualization as text ...
Osteoradionecrosis. Individuals who have a history of radiation treatment directed towards the head and neck area have an ... increased risk of developing a condition known as osteoradionecrosis after having a tooth extracted. This condition is ...
Osteoradionecrosis: a new concept of its pathophysiology. J Oral Maxillofac Surg. 1983 May. 41(5):283-8. [QxMD MEDLINE Link]. ... Osteoradionecrosis. Marx demonstrated conclusively that ORN is primarily an avascular aseptic necrosis rather than the result ... A new concept in the treatment of osteoradionecrosis. J Oral Maxillofac Surg. 1983 Jun. 41(6):351-7. [QxMD MEDLINE Link]. ... What is osteoradionecrosis (ORN) and how is hyperbaric oxygen therapy (HBOT) used in its treatment? ...
Palavras-chave : osteoradionecrosis; therapy; prevention; jaws.. · resumo em Português · texto em Português · pdf em Português ... DAVID, Edielly Fernanda et al. Therapeutic and preventative management of osteoradionecrosis: integrative literature review. ...
Managing osteoradionecrosis is an integral part of complication management in head and neck cancer patients. While essentially ... as the financial pitfalls and has highlighted the potential loop holes to be addressed in the management of osteoradionecrosis ... epidemiological concerns to sparking a potential discussion on the use of mesenchymal stem cell therapy in osteoradionecrosis ... Managing osteoradionecrosis is an integral part of complication management in head and neck cancer patients. While essentially ...
An 84 year old man presents with osteoradionecrosis after radiation of scalp vertex previously covered with the skin graft. ... Treatment of osteoradionecrosis of the calvarium is interesting in that it can be done with a radical approach or a very simple ... In conclusion, calvarial osteoradionecrosis is best treated with patience, expectant management such as serial debridement, and ... Posted in Melanoma, Patient Case Studies, Radiation Therapy and tagged calvarial osteoradionecrosis, calvarial resection, ...
Conclusion Mandibular osteoradionecrosis can be effectively and reproducibly produced in an athymic rat model. This will allow ... Conclusion Mandibular osteoradionecrosis can be effectively and reproducibly produced in an athymic rat model. This will allow ... Conclusion Mandibular osteoradionecrosis can be effectively and reproducibly produced in an athymic rat model. This will allow ... Conclusion Mandibular osteoradionecrosis can be effectively and reproducibly produced in an athymic rat model. This will allow ...
Late side effect of radiation in bones (Osteoradionecrosis). Late side effect of radiation in soft tissue (Soft tissue ...
A nomogram to predict osteoradionecrosis in oral cancer after marginal mandibulectomy and radiotherapy.. Renda, Levent; Tsai, ... There is no useful tool to clinically predict the occurrence of osteoradionecrosis (ORN) of the mandible quantitatively. The ...
Maxilla or mandible, chronic osteomyelitis, osteonecrosis, or osteoradionecrosis of. 9900 Melioidosis. 6318 ...
Osteoradionecrosis Osteoradionecrosis (ORN) is a condition of nonvital bone in a site of radiation injury. ORN can be ... osteoradionecrosis, radiation therapy, sequestrum, soft tissue necrosis, Xerostomia on December 29, 2011. by chzechze. ...
Some problems of mandibular osteoradionecrosis (str. 0-0) Zum Problem der Osteoradionekrose des Unterkiefers (str. 0-0) ...
Practice-Changing Innovations in the Management of Osteoradionecrosis Related Institutes & Services. Head & Neck Institute. At ...
Hansen T, Kunkel M, Kirkpatrick CJ, Weber A. Actinomyces in infected osteoradionecrosis--underestimated?. Hum Pathol. 2006 Jan ...
Although the proposed surgery typically poses risks of osteoradionecrosis and other healing issues in patients with prior oral ... Kennedys treating physicians at Duke diagnosed her with osteoradionecrosis. Today, Kennedy continues to suffer severe post- ...
Osteoradionecrosis. *Hemorrhagic cystitis. *Proctitis/enteritis. Peripheral vascular wounds *Venous ulcers. *Arterial ulcers ...
Does intensity-modulated radiation therapy lower the risk of osteoradionecrosis of the jaw? A long-term comparative analysis ...
We have established jaw osteoradionecrosis (ORN) pre-clinical model and shown that mesenchymal stem cell-based implantation can ... Cell Transplant (2012): Mesenchymal stromal cell-based treatment of jaw osteoradionecrosis in Swine. (PubMed: 22469112) ... We have established jaw osteoradionecrosis (ORN) pre-clinical model and shown that mesenchymal stem cell-based implantation can ...
Soft tissue radionecrosis and osteoradionecrosis. *Chronic refractory osteomyelitis. *Compromised skin grafts. *Actinomycosis ...
4] described the use of a radial periosteum free flap to treat early jaw osteoradionecrosis; the bone regeneration outcome was ...
In a study to assess the effect of eight gene polymorphisms on osteoradionecrosis (ORN) post radiation therapy of head and neck ... Influence of genetic background and oxidative stress response on risk of mandibular osteoradionecrosis after radiotherapy of ... It was hypothesized that individual radiosensitivity is effective in occurrence of osteoradionecrosis (ORN) post radiotherapy. ...
Osteomyocutaneous Free Fibula Flap Prevents Osteoradionecrosis and Osteomyelitis in Head and Neck Cancer Reconstruction * Full ...
Osteoradionecrosis in patients with salivary gland malignancies. Oral Oncol 57:1-5, 2016. e-Pub 2016. PMID: 27208837. ... Normal Tissue Complication Probability (NTCP) prediction model for osteoradionecrosis of the mandible in head and neck cancer ... Computed Tomography radiomics kinetics as early imaging correlates of osteoradionecrosis in oropharyngeal cancer patients. ... Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Establish Objective Osteoradionecrosis. ...
can cause a similar disorder called osteoradionecrosis). Sometimes, a bone infection (osteomyelitis Osteomyelitis Osteomyelitis ...
  • Objective We aim to create a model of mandibular osteoradionecrosis in athymic rats. (wustl.edu)
  • Conclusion Mandibular osteoradionecrosis can be effectively and reproducibly produced in an athymic rat model. (wustl.edu)
  • Some problems of mandibular osteoradionecrosis (str. (srce.hr)
  • Etiologically, a distinction is made between osteoradionecrosis, medication related osteonecrosis and osteomyelitis. (uni-wuerzburg.de)
  • BACKGROUND: To investigate whether low-intensity ultrasound accelerates healing in bone tissues close to dental implants with osteoradionecrosis (ORN) of the mandible and is suitable for development as a therapy in patients with dental implants receiving radiotherapy. (avmi.net)
  • CONCLUSIONS: Low-intensity ultrasound can accelerate the healing of bone tissues surrounding dental implants in osteoradionecrosis of the mandible animals. (avmi.net)
  • The article intends to review the bedrock of the pathology, ranging from pathophysiological and the epidemiological concerns to sparking a potential discussion on the use of mesenchymal stem cell therapy in osteoradionecrosis of mandible in head and neck cancer surgery and thus the ensuing future of the regenerative medicine. (aku.edu)
  • There is no useful tool to clinically predict the occurrence of osteoradionecrosis (ORN) of the mandible quantitatively. (bvsalud.org)
  • What Can I Do to Prevent Osteoradionecrosis? (curesearch.org)
  • Therefore, prior to and post oral surgery, patients who have had head and neck radiation may require hyperbaric oxygen treatments and antibiotic therapy to prevent osteoradionecrosis. (1stdentist.com)
  • Osteoradionecrosis (soft tissue and bone necrosis) can be spontaneous or secondary to trauma, extractions, or dental prostheses. (1stdentist.com)
  • Osteoradionecrosis (ORN) is a serious complication of radiation therapy in cancer treatment where radiated bone becomes necrotic and exposed. (wikipedia.org)
  • Although the proposed surgery typically poses risks of osteoradionecrosis and other healing issues in patients with prior oral radiation therapy, Dr. Prettyman did not discuss these risks with Kennedy or with Dr. DeAngelo. (findlaw.com)
  • Does intensity-modulated radiation therapy lower the risk of osteoradionecrosis of the jaw? (ugent.be)
  • Both of which serve to reduce the risk of postoperative complications such as osteoradionecrosis. (bris.ac.uk)
  • The radical approach of calvarial osteoradionecrosis treatment includes full-thickness calvarial resection and reconstruction with the microvascular free tissue transfer such as radial forearm free flap or latissimus free flap. (scarscenter.com)
  • A nomogram to predict osteoradionecrosis in oral cancer after marginal mandibulectomy and radiotherapy. (bvsalud.org)
  • Survivors who received high doses of radiation to the jaw area are at risk for osteoradionecrosis after dental procedures, such as getting a tooth pulled, or surgery involving the jawbone. (curesearch.org)
  • He investigates optimising outcomes from major head & neck cancer surgery and effectively treating and curing after effects such as osteoradionecrosis. (bradford.ac.uk)
  • This patient developed osteoradionecrosis (ORN) following radical radiotherapy. (medscape.com)
  • Osteoradionecrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
  • Managing osteoradionecrosis is an integral part of complication management in head and neck cancer patients. (aku.edu)
  • Scientists have been conducting investigations into the exact mechanisms of these changes to help create treatments since osteoradionecrosis (ORN) was first described by Regaud in 1922. (wikipedia.org)
  • I was in and out of hospital with infections from the osteoradionecrosis and could always ring or email our nurse to get seen in clinic or get advice. (macmillan.org.uk)
  • Treatment of osteoradionecrosis of the calvarium is interesting in that it can be done with a radical approach or a very simple conservative approach. (scarscenter.com)
  • Pentoxifylline and tocopherol with or without clodronate is a viable and effective treatment option in osteoradionecrosis. (cancer.org)
  • Also recently on here another member had a good experience with his osteoradionecrosis (ORN) Mavish had what they call Photodynamic laser treatment for osteoradionecrosis (ORN). (cancer.org)
  • Your dentist will then obtain information about your radiation treatment before doing any procedures that could lead to osteoradionecrosis. (curesearch.org)
  • Treatment for osteoradionecrosis can help control its symptoms. (curesearch.org)
  • Individuals who have a history of radiation treatment directed towards the head and neck area have an increased risk of developing a condition known as osteoradionecrosis after having a tooth extracted. (news-medical.net)
  • Mesenchymal stem cell therapy for treatment of osteoradionecrosis of m" by Ainulakbar Mughal, Merhaba Aftab et al. (aku.edu)
  • Moreover, the article has considered the management option in a developing nation thus explaining the procedural as well as the financial pitfalls and has highlighted the potential loop holes to be addressed in the management of osteoradionecrosis with stem cell therapy. (aku.edu)
  • In conclusion, calvarial osteoradionecrosis is best treated with patience, expectant management such as serial debridement, and careful observation for any intracranial exposure or symptoms. (scarscenter.com)
  • Extraction in patients receiving such therapy results in osteochemonecrosis, which is more severe than osteoradionecrosis and is more difficult to treat. (medscape.com)
  • Athymic rats provide an immunosuppressed environment whereby human stem cells and biomaterials can be used to investigate regenerative solutions for osteoradionecrosis, bridging the gap between in vivo testing and clinical application. (wustl.edu)
  • Then, I had osteoradionecrosis very early in 2018 in my upper jaw (maxilla) I did not have tooth extraction or anything to speed up or triger the osteoradionecrosis. (cancer.org)
  • if extraction is performed in the irradiated area, osteoradionecrosis results. (medscape.com)
  • Osteoradionecrosis (ORN) is a condition of nonvital bone in a site of radiation injury. (medscape.com)
  • Osteoradionecrosis is a problem with bone healing, particularly in the jawbone. (curesearch.org)
  • Osteoradionecrosis is difficult to prevent and treat. (wikipedia.org)
  • This graph shows the total number of publications written about "Osteoradionecrosis" by people in this website by year, and whether "Osteoradionecrosis" was a major or minor topic of these publications. (sdsu.edu)
  • Osteoradionecrosis can be diagnosed by physical examination and imaging studies. (curesearch.org)
  • In this month's conference we presented a man who developed osteoradionecrosis after radiation of scalp vertex previously covered with the skin graft. (scarscenter.com)