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*  Centella 70 Toning Swab | Free People UK
Shop our Centella 70 Toning Swab at FreePeople.com. Share style pics with FP Me, and read & post reviews. Free shipping ... Made with 70% pure centella extract, a plant powerhouse known for its calming and anti-redness properties, this toning swab ... Made with 70% pure centella extract, a plant powerhouse known for its calming and anti-redness properties, this toning swab ... Ingredients: Centella Asiatica Extract, Alcohol, Lactic Acid, Tromethamine, Dipropylene Glycol, 1,2-Hexanediol, Water, Glycerin ...
https://www.freepeople.com/uk/shop/centella-70-toning-swab/
*  Hepatotoxicidad asociada al consumo de Centella asiática
The herb Centella asiatica (Centella asiatica Linn Urban) comes from the Eastern world, especially India and Sri Lanka. For ... Centella asiatica (Centella asiatica Linn Urban) is commercialized for multiple conditions. Its active principles are ... Centella asiatica. Apoptosis. Ursodeoxycholic acid.. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of ... At present Centella asiatica is used for dementias and cognitive disorders (22,23), in the treatment of chronic venous ...
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082005000200006&lng=ye&nrm=iso
*  Arthritis D.C. (before Centella) by Alan Russell Maslen | Waterstones
... before Centella) by Alan Russell Maslen from Waterstones today! Click and Collect from your local Waterstones or get FREE UK ... Publisher: Kenneth V.Jackson.Centella Probe (UK) ISBN: 9780954795603 Dimensions: 210 x 148 mm Edition: 3rd Revised edition ... Arthritis D.C. (before Centella): Or: The Paradoxical Pennywort (Aus) (Paperback). Alan Russell Maslen (author) Sign in to ...
https://www.waterstones.com/book/arthritis-d-c-before-centella/alan-russell-maslen/9780954795603
*  Asiatic acid ≥98% (HPLC), from Centella asiatica | Sigma-Aldrich
98% (HPLC), from Centella asiatica Synonym: 2α,23-Dihydroxyursolic acid, Dammarolic acid, NSC 166063 ...
https://www.sigmaaldrich.com/catalog/product/sigma/a2612?lang=en®ion=US
*  Centella Asiatica Manufacturers, Suppliers & Exporters in India
Contact to Centella Asiatica Exporters in India, Centella Asiatica Wholesalers, Centella Asiatica Distributors and Traders from ... Search Indian Centella Asiatica Manufacturers and Suppliers Details - ... Deals in centella asiatica, Mustard Oil, Neem Oil, Essential Oils, Rosemary Oil, pepper oil, Herbal Extract, Nutmeg Mace Oil, ... Deals in Centella Asiatica, Ginger, junglee haldi, Stevia Powder, kalimusli, Stevia Cultivation, kali haldi, Lemongrass, dry ...
http://www.indianyellowpages.com/india/manufacturers/c/centella-asiatica.htm
*  Browse Products Containing: CENTELLA ASIATICA (GOTU KOLA) EXTRACT || Skin Deep® Cosmetics Database | EWG
Products containing CENTELLA ASIATICA (GOTU KOLA) EXTRACT made by company: WWBE There are no products in the database that ...
http://www.ewg.org/skindeep/browse.php?comp_id=3927&ingred06=701197
*  Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models
... Yun Zhao,1,2 Ping Shu,1 ... Yun Zhao, Ping Shu, Youzhi Zhang, et al., "Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in ...
https://www.hindawi.com/journals/omcl/2014/154295/cta/
*  Centella asiatica Attenuates D-Galactose-Induced Cognitive Impairment, Oxidative and Mitochondrial Dysfunction in Mice
Centella Asiatica (CA) Improved on Behavioral Alteration in D-Galactose-Treated Mice. (I) Morris Water Maze. D-galactose- ... Table 1: Effect of Centella asiatica (CA; 150 and 300 mg/kg, p.o.) on memory performance in Morris water maze in D-galactose- ... Table 2: Effect of Centella asiatica (CA; 150 and 300 mg/kg, p.o.) on memory performance in elevated plus maze paradigm in D- ... Table 3: Effect of Centella asiatica (CA; 150 and 300 mg/kg, p.o.) on D-gal-induced oxidative stress parameters in rat brain. ...
https://www.hindawi.com/journals/ijad/2011/347569/
*  Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models
... Yun Zhao,1,2 Ping Shu,1 ... R. Gupta and S. J. S. Flora, "Effect of Centella asiatica on arsenic induced oxidative stress and metal distribution in rats," ... Y. H. Siddique, G. Ara, T. Beg, M. Faisal, M. Ahmad, and M. Afzal, "Protective role of Centella asiatica L. extract against ... M. H. V. Kumar and Y. K. Gupta, "Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress ...
https://www.hindawi.com/journals/omcl/2014/154295/ref/
*  Gotu Kola Centella asiatica Indian Pennywort -Mr Supplement Austra
Its scientific name is Centella asiatica. It is generally used to flavour curries or other dishes, blended to make cold drinks ...
https://www.mrsupplement.com.au/gotu-kola
*  Centella asiatica is discussed in the July 2009 Ageless newsletter.
Centella is also included in our very popular Healing Cream that has helped thousands of people with skin problems and skin ... Centella asiatica a herb with amazing properties is discussed in this newsletter. ... Centella asiatica (Gotu kola). Summing up the benefits of Centella asiatica is difficult; as there are so many, but in short it ... Centella asiatica extract is an extract of the leaves and roots of the Hydrocotyle Centella asiatica. It is classed as a ...
http://ageless.co.za/200907-centella-asiatica.htm
*  Centella - Wikipedia
E.van Wyk Centella laevis Adamson Centella lanata Compton Centella lasiophylla Adamson Centella linifolia (L.f.) Drude Centella ... Adamson Centella scabra Adamson Centella sessilis Adamson Centella stenophylla Adamson Centella stipitata Adamson Centella ... Centella brachycarpa M.Schub. & B.-E.van Wyk Centella caespitosa Adamson Centella calcaria M.Schub. & B.-E.van Wyk Centella ... Centella abbreviata (A. Rich.) Nannf. Centella affinis (Eckl. & Zeyh.) Adamson Centella annua M.Schub. & B.-E.van Wyk Centella ...
https://en.wikipedia.org/wiki/Centella
*  Centella Asiatica Extract - Lotioncrafter LLC
Centella Asiatica (also known as gotu kola and Indian pennywort) is a perennial creeping plant which grows around the Indian ... Centella Asiatica (also known as gotu kola and Indian pennywort) is a perennial creeping plant which grows around the Indian ... INCI: Glycerin (and) Water (and) Hydrocotyl (Centella Asiatica) Extract. This product should be added to a formulation at the ... Studies have shown that the main constituents of Centella asiatica (Asiatic acid, madecassic acid, and asiaticoside) increase ...
http://www.lotioncrafter.com/centella-asiatica-extract.html
*  Centella asiatica Improves Physical Performance and Health-Related Quality of Life in Healthy Elderly Volunteer
... Lugkana Mato,1 ... Y. Chen, T. Han, L. Qin, Y. Rui, and H. Zheng, "Effect of total triterpenes from Centella asiatica on the depression behavior ... L. Suguna, P. Sivakumar, and G. Chandrakasan, "Effects of Centella asiatica extract on dermal wound healing in rats," Indian ... L. Incandela, G. Belcaro, M. T. De Sanctis et al., "Total triterpenic fraction of Centella asiatica in the treatment of venous ...
https://www.hindawi.com/journals/ecam/2011/579467/ref/
*  Ayurveda health benefits of Manduka Parni (Centella Asiatica)-gotu kola by Savitha Suri
Centella Asiatica) or gotu kola also known as Indian pennywort is a small herb which grows in tropical swampy areas. This herb ... The herb Manduka Parni (Centella Asiatica) or gotu kola also known as Indian pennywort is a small herb which grows in tropical ... Scientists are able to determine chemical composition of Centella asiatica or gotukola contains various alkaloids, triterpenes ...
https://www.boloji.com/articles/14269/ayurveda-health-benefits-of-manduka-parni
*  Centella asiatica - Wikipedia
Centella asiatica, commonly known as centella, Asiatic pennywort or Gotu kola, is a herbaceous, frost-tender perennial plant in ... Centella asiatica in West African plants - A Photo Guide. "Pharmacological Review on Centella asiatica: A Potential Herbal Cure ... "Plant Profile for Centella asiatica". Retrieved 15 July 2012. Floridata. "Centella asiatica". Retrieved 15 July 2012. Meschino ... "Centella asiatica". Alabama Plant Atlas. Retrieved 17 August 2015. "Centella asiatica". Atlas of Florida Vascular Plants. ...
https://en.wikipedia.org/wiki/Centella_asiatica
*  Roca Centella - Wikipedia
Roca Centella is a mountain of Catalonia, Spain. It has an elevation of 1,000 metres above sea level. This mountain is part of ...
https://en.wikipedia.org/wiki/Roca_Centella
*  Donation & The Many Benefits Of Gotu Kola (Centella asiatica) - Infinite Unknown
Centella asiatica has been used as a medicine in the Ayurvedic tradition of India (for thousands of years) and is listed in the ... Categories Announcements, HealthTags Alzheimer, Announcement, Brain, Centella asiatica, Dementia, Gotu Kola, Herbs, Insomnia, ... Gotu kola (Centella asiatica) has been used to treat many conditions for thousands of years in India, China, and Indonesia. ... Gotu kola (Centella asiatica) is a perennial groundcover that's a member of the same plant family as parsley and carrots. ...
https://infiniteunknown.net/2016/05/17/donation-49/
*  Centella asiatica ( Linn . ) Urban óA Review - Semantic Scholar
Centella asiatica (Linn.) Urban is valued in Indian systems of medicine for improving memory and for the treatment of nervine ... Centella asiatica ( Linn . ) Urban óA Review. @inproceedings{Jamil2010CentellaA, title={Centella asiatica ( Linn . ) Urban {\'o ... Centella asiatica treatment during postnatal period enhances learning and memory in mice.. *Sulochana B Rao, Mattu Chetana, ... Effect of Centella asiatica on arsenic induced oxidative stress and metal distribution in rats.. *Richa Gupta, Swaran J. S. ...
https://www.semanticscholar.org/paper/Centella-asiatica-%28-Linn-.-%29-Urban-%C3%B3A-Review-Jamil-Nizami/8f315982a6024ac49eb5640a3ab17c33339c9701
*  Centella Asiatica: Herb of the Crown Chakra - Naturopathic Doctor News and Review
Centella asiatica. Centella asiatica is a plant in the Apiaceae family that grows in moist areas and thrives in and around ... The Centella-only group experienced 82% relief of symptoms and disappearance of inflammation, whereas the surgery-plus-Centella ... 1 group receiving Centella alone and the other group receiving surgical scar revision plus Centella; both groups were dosed at ... Centella asiatica is an important herb in the fast-paced world in which we all live. Restoring the sattva in our lives is ...
https://ndnr.com/botanical-medicine/centella-asiatica-herb-of-the-crown-chakra/
*  Determination of Triterpenes in Centella asiatica (Gotu Kola) by HPLC-CAD | SelectScience
... and the assay of triterpene content in a Centella asiatica extract sample using the Corona CAD detector is shown. ... Application Note: Determination of Triterpenes in Centella asiatica (Gotu Kola) by HPLC-CAD. 3 May 2012 ... and the assay of triterpene content in a Centella asiatica extract sample using the Corona CAD detector is shown. ...
http://www.selectscience.net/application-notes/determination-of-triterpenes-in-centella-asiatica-
*  Antiproliferative Constituents from Umbelliferae Plants VII. Active Triterpenes and Rosmarinic Acid from <i>Centella...
The antiproliferative constituents in the MeOH extract from the aerial parts of Centella asiatica were investigated. Activity- ...
https://www.jstage.jst.go.jp/article/bpb/28/1/28_1_173/_article
*  Hibiscus Sabdariffa and Centella Asiatica in the Treatment of Anemia by Iron Deficiency - Full Text View - ClinicalTrials.gov
Hibiscus Sabdariffa and Centella Asiatica in the Treatment of Anemia by Iron Deficiency. This study has been completed. ... Patients will receive a combination of Hibiscus sabdariffa (powdered dry plant), 200 mg, BID, and Centella asiatica tincture, ... Hibiscus sabdariffa plus Centella asiatica). The main outcome will be hemoglobin, measured before and after 6 weeks. ...
https://clinicaltrials.gov/ct2/show/NCT01414374?term=herbal+medicine&recr=Open&rank=7
*  In vitro antibacterial and cytotoxic activity of leaf extracts of Centella asiatica (L.) Urb , Warburgia salutaris (Bertol. F.)...
Antioxidant and cytotoxic activities of Centella asiatica (L) Urb. Int J Mol Sci. 2009;10(9):3713-21.CrossRefGoogle Scholar ... In vitro antibacterial and cytotoxic activity of leaf extracts of Centella asiatica (L.) Urb, Warburgia salutaris (Bertol. F.) ... The MIC (mg/ml) values of Centella asiatica, Curtisia dentate and Warbugia salutaris extracts against bacteria ... The MBC (mg/ml) values of Centella asiatica, Curtisia dentate and Warbugia salutaris extracts against bacteria ...
https://link.springer.com/article/10.1186%2Fs12906-018-2378-3
*  China Total Triterpene 10%-80% ( Centella Asiatica L. ) Products, China Total Triterpene 10%-80% ( Centella Asiatica L. )...
Centella Asiatica L. ) Products Products at centella asiatica ,centella asiatica pure powder hplc ,centella asiatica extract ... Centella Asiatica L. ) Products Suppliers and Manufacturers Directory - Source a Large Selection of Total Triterpene 10%-80% ( ... centella asiatica centella asiatica pure powder hplc centella asiatica extract centella asiatica pure powder ... Centella Asiatica Extract Herba Centellae Powder for cosmetic products Hunan Greenland Plant Resource Development Co., Ltd. ...
http://www.alibaba.com/countrysearch/CN/total-triterpene-10%2525--80%2525-%2528-centella-asiatica-l.-%2529-products.html

*  Centella
E.van Wyk Centella laevis Adamson Centella lanata Compton Centella lasiophylla Adamson Centella linifolia (L.f.) Drude Centella ... Adamson Centella scabra Adamson Centella sessilis Adamson Centella stenophylla Adamson Centella stipitata Adamson Centella ... Centella brachycarpa M.Schub. & B.-E.van Wyk Centella caespitosa Adamson Centella calcaria M.Schub. & B.-E.van Wyk Centella ... Centella abbreviata (A. Rich.) Nannf. Centella affinis (Eckl. & Zeyh.) Adamson Centella annua M.Schub. & B.-E.van Wyk Centella ...
*  Centella asiatica
... , commonly known as centella, Asiatic pennywort or Gotu kola, is a herbaceous, frost-tender perennial plant in ... Centella asiatica in West African plants - A Photo Guide. "Pharmacological Review on Centella asiatica: A Potential Herbal Cure ... "Plant Profile for Centella asiatica". Retrieved 15 July 2012. Floridata. "Centella asiatica". Retrieved 15 July 2012. Meschino ... "Centella asiatica". Alabama Plant Atlas. Retrieved 17 August 2015. "Centella asiatica". Atlas of Florida Vascular Plants. ...
*  Roca Centella
... is a mountain of Catalonia, Spain. It has an elevation of 1,000 metres above sea level. This mountain is part of ...
*  Lynx Central Station
Centella Consulting. "LYNX Central Station". Sunrail.com. Retrieved 2010-06-06. "LYNX About Us". Golynx.com. Retrieved 2010-06- ...
*  Bromo Tengger Semeru National Park
and Centella asiatica. The Tengger Sand Sea in Tengger Caldera is a special ecosystem. The area is covered in volcanic ...
*  List of plants of Burkina Faso
Centella asiatica (L.) Urb. Centrosema pubescens Benth. Centrostachys aquatica (R.Br.) Wall. Ceratophyllum demersum L. ...
*  El Texano
Centella, Teddy (June 6, 2015). "En un día como hoy… 1981: Promociones Mora llega a la Arena México, Los Misioneros, pelones… ...
*  Princesa Sugehit
Centella, Teddy (April 2, 2015). "En un día como hoy… 1943: Se inaugura la Arena Coliseo - 2004: Dark Angel pierde la máscara ...
*  Prudencia Ayala
"Prudencia Ayala, 'hija de la centella'". Retrieved April 27, 2007. Lycos. "Prudencia Ayala". Retrieved April 27, 2007. "Central ...
*  Gran Hamada
Tomo I. Centella, Teddy (June 6, 2015). "En un día como hoy… 1981: Promociones Mora llega a la Arena México, Los Misioneros, ...
*  List of Apiaceae genera
Centella L. Chlaenosciadium C. Norman Mackinlaya F. Muell. Micropleura Lag. Pentapeltis (Endl.) Bunge Platysace Bunge ...
*  Henry Georges Fourcade
asema M.B.Bayer Apiaceae: Centella verticillata (Thunb.) Fourc. Apocynaceae: Carissa cordata (Mill.) Fourc. Asclepiadaceae: ... Amphithalea fourcadei Compton Aspalathus fourcadei L.Bolus Babiana fourcadei G.J.Lewis Centella fourcadei Adamson Corymbium ...
*  List of MeSH codes (B06)
... centella (wd , gwp gwe g , in it p) MeSH B06.388.100.075.199 --- cnidium (wd , gwp gwe g , in it p) MeSH B06.388.100.075.211 ...
*  Chrysoritis uranus
The larvae feed on Centella, Aspalathus, and Zygophyllum species. They are attended to by Crematogaster liengmei ants. ...
*  Per Karl Hjalmar Dusén
Apiaceae) Azorella dusenii H.Wolff (Apiaceae) Centella dusenii Nannf. (Apiaceae) Trachymene dusenii (Domin) B.L.Burtt ( ...
*  Communist Party of Spain
Since 2009, the general secretary is José Luis Centella. Notably, PSUC, the Catalan referent of PCE, did not reverse its ...
*  List of wort plants
Also Gotu Kola (Centella asiatica) and species from genus Hydrocotyle. Pepperwort - Lepidium latifolium; Lepidium campestre; ...
*  Myrtillin
... and Centella asiatica plant.[citation needed] It is also present in yeast and oatmeal.[citation needed] The sumac fruits ...
*  Magnolia jardinensis
Common names include Gallinazo blanco, copachí and centello. This tree can reach a height of up to 25 m and up to 60 cm in ...
*  Stretch marks
The safety in pregnancy of one ingredient, Centella asiatica, has been questioned. Evidence on treatments for reducing the ...
*  Human enhancement
Gohil, Kashmira J.; Patel, Jagruti A.; Gajjar, Anuradha K. "Pharmacological Review on Centella asiatica: A Potential Herbal ...
*  Leaf vegetable
Gotukola (Centella asiatica) Swiss chard water spinach Sabzi Khordan, an Iranian salad-like dish. List of leaf vegetables Leaf ...
*  Sasanka Chandra Bhattacharyya
Later, his work with B. Lythgoe at Cambridge University focused on the anti-leprosy properties of Centella asiatica where they ... Terpenoids Vetiver Oil Musk Centella asiatica India portal Chemistry portal Please see Selected bibliography section "Directors ... working on Centella asiatica, a plant used for treating leprosy. He started his career as a research chemist with Herts ...
*  Wildlife of South Korea
Centella asiatica. Reynoutria elliptica, Hydrangea serrata, Eleutherococcus senticosus, Aconitum napiforme, Schisandra repanda ...
*  CYP3A4
"Investigation of CYP3A4 and CYP2D6 Interactions of Withania somnifera and Centella asiatica in Human Liver Microsomes". ...

(1/25) Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, from Centella asiatica cultivated in Sri Lanka.

Ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, were isolated from the aerial parts of Centella asiatica (L.) Urban cultivated in Sri Lanka together with madecassoside, asiaticoside, asiaticoside B, and sceffoleoside A. The chemical structures of centellasaponins B, C, and D were determined on the basis of chemical and physicochemical evidence to be madecassic acid 28-O-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyranoside, madasiatic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyra noside, and 3beta,6beta,23-trihydroxyolean-12-en-28-oic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta-D-glucopyra noside, respectively.  (+info)

(2/25) Antiproliferative constituents from Umbelliferae plants VII. Active triterpenes and rosmarinic acid from Centella asiatica.

The antiproliferative constituents in the MeOH extract from the aerial parts of Centella asiatica were investigated. Activity-guided fractionation of MeOH extract resulted in the isolation of ursolic acid lactone, ursolic acid, pomolic acid, 2alpha,3alpha-dihydroxyurs-12-en-28-oic acid, 3-epimaslinic acid, asiatic acid, corosolic acid, and rosmarinic acid. Antiproliferative activity of the isolated compounds against human gastric adenocarcinoma (MK-1), human uterine carcinoma (HeLa), and murine melanoma (B16F10) cells was estimated.  (+info)

(3/25) Hepatotoxicity associated with the ingestion of Centella asiatica.

BACKGROUND: Hepatotoxicity due to herbal remedies is being increasingly recognized. Centella asiatica (Centella asiatica Linn Urban) is commercialized for multiple conditions. Its active principles are pentacyclic triterpenic saponosides (asiaticoside, madecassoside). CLINICAL CASE STUDIES: We present three women (61, 52 and 49 years old) who developed jaundice after taking Centella asiatica for 30, 20 and 60 days. Respective laboratory tests: ALT: 1193, 1694 and 324 U/L; ALP: 503, 472 and 484 U/L; bilirubin: 4.23, 19.89 and 3.9 mg/dl. The first patient also had ASMA 1/160 and AMA 1/320. Respective pathological diagnoses: granulomatous hepatitis with marked necrosis and apoptosis; chronic hepatitis with cirrhotic transformation and intense necroinflammatory activity, and granulomatous hepatitis. All patients improved with Centella asiatica discontinuation, and ursodeoxycholic acid 10 mg/kg/day. The first patient took Centella asiatica again, with recurrence of the damage. The second one had taken this herb a year before. CONCLUSIONS: Many plants synthesize hepatotoxic compounds. Germander, Skullcap and Glycyrrhizin contain di- or triterpenic active principles, which can produce hepatic injury by promoting apoptosis and altering cell membranes. We hypothesize that these mechanisms may have resulted in injuries associated with Centella asiatica. The presence of autoantibodies and granulomas also favors an immune-mediated mechanism. Ursodeoxycholic acid has anti-apoptotic properties, but we cannot rule out that Centella asiatica discontinuation alone may have resulted in patient improvement.  (+info)

(4/25) Cloning and expression of a farnesyl diphosphate synthase in Centella asiatica (L.) Urban.

A cDNA encoding farnesyl diphosphate synthase (FPS; EC2.5.1.1/EC2.5.1.10) was isolated from Centella asiacita (L.) Urban, using degenerate primers based on two highly conserved domains. A full-length cDNA clone was subsequently isolated by rapid amplification of cDNA ends (RACE) PCR. The sequence of the CaFPS (C. asiatica farnesyl diphosphate synthase) cDNA contains an open reading frame of 1029 nucleotides encoding 343 amino acids with a molecular mass of 39.6 kDa. The deduced CaFPS amino acid sequence exhibits 84, 79, and 72%, identity to the FPSs of Artemisia annua, Arabidopsis thaliana, and Oryza sativa, respectively. Southern blot analysis suggested that the C. asiatica genome contains only one FPS gene. An artificially expressed soluble form of the CaFPS was identified by SDS-PAGE. It had high specific activity and produced farnesyl diphosphate as the major isoprenoid.  (+info)

(5/25) Immunomodulatory activities of Centella asiatica and Rhinacanthus nasutus extracts.

Centella asiatica (CA) and Rhinacanthus nasutus (RN )have been used for treatment of various illnesses, but the mechanisms of action remain largely unknown. This study focused on the influence of CA and RN extracts on cell-mediated and humoral immune responses. In human peripheral blood mononuclear cells (PBMCs), CA (water extract) and RN (water and ethanol extracts) significantly increased proliferation and the production of IL-2 and TNF-alpha. In contrast, an ethanol extract of CA inhibited human PBMC mitogenesis and the production of IL-2 and TNF-alpha. BALB/c mice treated with CA extracts (100 mg/kg bw) showed higher responses to both primary and secondary antibodies against BSA when compared with non-treated group. Only the secondary antibody response was increased in RN extract-treated mice. The present study revealed immunomodulating activity of CA and RN extracts with regard to both non-specific cellular and humoral immune responses. The data available to date suggest that they may have chemopreventive or anticancer potential.  (+info)

(6/25) In vitro screening of five local medicinal plants for antibacterial activity using disc diffusion method.

Medicinal plants have many traditional claims including the treatment of ailments of infectious origin. In the evaluation of traditional claims, scientific research is important. The objective of the study was to determine the presence of antibacterial activity in the crude extracts of some of the commonly used medicinal plants in Malaysia, Andrographis paniculata, Vitex negundo, Morinda citrifolia, Piper sarmentosum, and Centella asiatica. In this preliminary investigation, the leaves were used and the crude extracts were subjected to screening against five strains of bacteria species, Methicillin Resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli, using standard protocol of Disc Diffusion Method (DDM). The antibacterial activities were assessed by the presence or absence of inhibition zones and MIC values. M. citrifolia, P. sarmentosum and C. asiatica methanol extract and A. paniculata (water extract) have potential antibacterial activities to both gram positive S. aureus and Methicillin Resistant S. aureus (MRSA). None of the five plant extracts tested showed antibacterial activities to gram negative E. coli and K. pneumoniae, except for A. paniculata and P. sarmentosum which showed activity towards P. aeruginosa. A. paniculata being the most potent at MIC of 2 g/disc. This finding forms a basis for further studies on screening of local medicinal plant extracts for antibacteria properties.  (+info)

(7/25) The anti-thrombotic active constituents from Centella asiatica.

The in vitro effects of a methanol extract from the aerial parts of Centella asiatica on shear-induced platelet activation and coagulation were assessed after oral administration to rats, by subjecting non-anticoagulated blood to haemostatometry. 3,5-Di-O-caffeoyl quinic acid, 1,5-di-O-caffeoyl quinic acid, 3,4-di-O-caffeoyl quinic acid, 4,5-di-O-caffeoyl quinic acid, and chlorogenic acid, together with asiaticoside, kaempferol, quercetine, kaempferol-3-O-beta-D-glucoside and quercetin-3-O-beta-D-glucoside were all isolated from the methanol extract. Amongst these, only 3,5-di-O-caffeoylquinic acid showed significant inhibition of shear-induced platelet activation and dynamic coagulation. The reactive curve of the inhibitory effect on the platelet reaction and the dynamic coagulation showed a bell-shape.  (+info)

(8/25) Dechlorophyllation by electrocoagulation.

Electrocoagulation was used for dechlorophyllation of alcoholic extracts from five plants. The results showed that for every plant extract studied, electrocoagulation was more efficient than the classical solvent extraction method in removing plant pigments, while not affecting the important secondary metabolites in those extracts.  (+info)


  • Extract
  • Made with 70% pure centella extract, a plant powerhouse known for its calming and anti-redness properties, this toning swab dissolves dead skin and excess dirt and oils with the power of lactic acid. (freepeople.com)
  • J. S. Guo, C. L. Cheng, and M. W. Koo, "Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats," Planta Medica , vol. 70, no. 12, pp. 1150-1154, 2004. (hindawi.com)
  • T. K. Chatterjee, A. Chakraborty, M. Pathak, and G. C. Sengupta, "Effects of plant extract Centella asiatica (Linn. (hindawi.com)
  • K. G. Mohandas Rao, S. Muddanna Rao, and S. Gurumadhva Rao, " Centella asiatica (L.) leaf extract treatment during the growth spurt period enhances hippocampal CA3 neuronal dendritic arborization in rats," Evidence-Based Complementary and Alternative Medicine , vol. 3, no. 3, pp. 349-357, 2006. (hindawi.com)
  • The antiproliferative constituents in the MeOH extract from the aerial parts of Centella asiatica were investigated. (go.jp)
  • herbal
  • The study aims to investigate the prevalence of genetic polymorphisms in adults with iron deficiency and anemia, and the responses to two different treatments: iron sulphate and a composite herbal medicine (Hibiscus sabdariffa plus Centella asiatica). (clinicaltrials.gov)
  • cognitive
  • At present Centella asiatica is used for dementias and cognitive disorders (22,23), in the treatment of chronic venous insufficiency, diabetic microangiopathy and atherosclerotic plaques (24,25), and in dermatological pathologies such as wound healing and scars (26), prevention of striae gravidarum (27), and psoriasis (28). (isciii.es)
  • Therefore, present study has been conducted in order to explore the possible role of Centella asiatica against D-galactose induced cognitive impairment, oxidative and mitochondrial dysfunction in mice. (hindawi.com)
  • treatment
  • Six weeks Centella asiatica (150 and 300 mg/kg, p.o) treatment significantly improved behavioral alterations, oxidative damage and mitochondrial enzyme complex activities as compared to contro l (D-galactose). (hindawi.com)
  • Research has shown that asiaticoside can also help provide treatment for leprosy and skin tuberculosis, as the bacteria are coated in a wax-like substance that the body's immune system cannot penetrate, but this waxy coating is dissolved by centella, thereby allowing the body's immune system to destroy the bacteria. (ageless.co.za)
  • Centella asiatica treatment during postnatal period enhances learning and memory in mice. (semanticscholar.org)
  • Effect
  • Present study highlights the protective effect of Centella asiatica against D-galactose induced behavioral, biochemical and mitochondrial dysfunction in mice. (hindawi.com)
  • medicine
  • K. G. Mohandas Rao, S. Muddanna Rao, and S. Gurumadhva Rao, "Enhancement of amygdaloid neuronal dendritic arborization by fresh leaf juice of Centella asiatica (Linn) during growth spurt period in rats," Evidence-Based Complementary and Alternative Medicine , vol. 6, no. 2, pp. 203-210, 2009. (hindawi.com)
  • Review
  • The present review is an up-to-date and comprehensive literature analysis of the chemistry, pharmacology and clinical trials on Centella drug. (semanticscholar.org)
  • Beauty
  • Apart from the beauty use of Centella asiatica, it is also of great help when used on post-operation and trauma scars , as it promotes healing , yet helps to prevent the formation of excess scar tissue . (ageless.co.za)